Rhodopsins are one of the most studied photoreceptor protein families, and ion‐translocating rhodopsins, both pumps and channels, have recently attracted broad attention because of the development of optogenetics. Recently, a new functional class of ion‐pumping rhodopsins, an outward Na+ pump, was discovered, and following structural and functional studies enable us to compare three functionally different ion‐pumping rhodopsins: outward proton pump, inward Cl− pump, and outward Na+ pump. Here, we review the current knowledge on structure‐function relationships in these three light‐driven pumps, (...) mainly focusing on Na+ pumps. A structural and functional comparison reveals both unique and conserved features of these ion pumps, and enhances our understanding about how the structurally similar microbial rhodopsins acquired such diverse functions. We also discuss some unresolved questions and future perspectives in research of ion‐pumping rhodopsins, including optogenetics application and engineering of novel rhodopsins. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Ōmori Shōzō and Kotodama Theory: How Can We Overcome the Need for Bodily Encounters?Maki SatoIntroductionŌmori Shōzō is known for his theory of tachi-araware monism. Tachiaraware monism is his attempted counter-argument to the Cartesian dualism of the object–subject divide, or in his words, a divide between physical (butsuri, mono, science, object) and non-physical consciousness (ishiki, koto, perception, incident), perception (chikaku, 知覚) and conception (shikō, 思考). His concept of Kasane-egaki is (...) also often cited as a core concept of his theory of time.1 The main aim of this paper is to first overview the works of Ōmori since there is only a limited amount of his translated work so far.2 Consecutively, the paper focuses on Ōmori’s theory of kotodama and its related arguments with an intention to expand his concept of Kowaburi into the ethics of online encounters during the pandemic.The world in 2020 was suddenly forced to face the pandemic caused by COVID-19. What COVID-19 alerted us to is tremendous, and there are countless problems that the invisible virus has revealed. Among those are the hidden problems of contemporary society, not limited to the discrimination among races, gender, and jobs (white-collars versus essential workers), the problem of zoonosis, and the related environmental problems (climate change and intrusion into wild nature) caused by over-exploitation of nature. In developed countries, most students and those serving as intellectual workers face their daily lives being overly occupied with online lectures and meetings. COVID-19 worked to normalize remote work, which further normalized and forced our everyday life to shift to cyberspace. [End Page 101]In introducing and overviewing Ōmori’s philosophy, this paper attempts to see the current situation through Ōmori’s philosophy to draw out some ethical implications related to non-physical online encounters and how we can perceive human interactions and relationships under such conditions. Under the constraints caused by COVID-19, humans’ limitless desires to interact with others are expanding more so to the sphere of cyberspace, leading to technological development, such as VR. In short, first, the paper overviews Ōmori’s philosophy. Second, through the overview of Ōmori’s philosophy, the paper seeks adaptable philosophy of his that may work as soft binding grounding ethics for cyberspace encounters where substantial bodily encounters are void. In doing so, the paper intends to draw out weak binding ethics implied in Ōmori’s philosophy that may work to empathetically engage with others in cyberspace where embodied encounters with others are dissolved.Ōmori Shōzō and His Philosophy: A Short Introduction and OverviewIn his short essay introducing the Japanese philosophy of the 1970s, Yasuo Kobayashi coined the term “Komaba quartet” by selecting four active eminent philosophers based on the Komaba campus at the University of Tokyo.3 Among them is Ōmori Shōzō (1921–97), aligning with Hiromatsu Wataru (1933–94), Sakabe Megumi (1936–2009), and Inoue Tadashi (1926–2014). Ōmori is the oldest of the Komaba quartet and received higher education before World War II. He served at the Naval Technology Institute Mitaka Laboratory during the war with his physics degree from the Tokyo Imperial University.4 After the war, he studied philosophy at the University of Tokyo with an interest in phenomenology, leading him to study at Harvard and Stanford in the United States.During his professorship at the University of Tokyo, he inspired countless students who are now leading the philosophy academy in Japan, such as Noe Keiichi (1949–) and Noya Shigeki (1954–). In the round-table discussion titled “Explanatory Round-Table on the Charm of Ōmori’s Philosophy,” four of his former students—Iida Takashi and Tanji Nobuharu, in addition to Noe and Noya—worked on selecting his works. It is impressive to read that all four [End Page 102] of them recall how exciting and inspiring it was to take his classes.5 Iida recalls that Ōmori’s classes were exceptional since philosophy courses were all about reading, with might and main, the texts written in a language other than Japanese at the University of Tokyo. However, Ōmori, with his postwar American education, welcomed discussion with the students and was keen on questioning... (shrink)

Originally published as 「明治の哲学界：有機体の哲学とその系譜」in 井上克人編『豊饒なる明治』, Kansai Daigaku Shuppannbu, 2012, 3–22. Translated by Morisato Takeshi. German Idealism was introduced to Japanese intellectuals in the middle of Meiji era and was mainly received from a mystical or religious perspective, as we see in Inoue Tetsujirō’s “harmonious existence,” Inoue Enryō’s “unity of mind and body,” and Kiyozawa Manshi’s “existentialism.” Since these theories envisioned true reality as a unified and living whole, I group them under the label “philosophy of organism” and from (...) there argue that their conviction that “all is truth and truth is all” was shaped in large part by the Awakening of Faith in the Mahayana. The understanding of Buddhist concepts by Meiji philosophers was philosophical in its content, and those who devoted themselves to the study of Western philosophy were encouraged to describe Eastern thought in Western philosophical terms. As a result, the philosophical world of the Meiji era developed an original standpoint that unified Eastern and Western perspectives by means of a logic of “phenomena-in-reality.”. (shrink)

Study of Vaiśeṣika philosophy with special reference to Vaiśeṣikadaśapadārthaśāstra.

To explain why students learn effectively by teaching, explaining to others in particular, Koh and colleagues advanced the retrieval practice hypothesis, which attributes the learning benefits entirely to the effect of practicing retrieval, that is, effortfully recalling to-be-taught information for the provision of instructional explanations. After delineating the rationale behind the retrieval practice hypothesis, the current situation of research, and the limitations of the existing approach, this paper proposes three tests for the evaluation of the hypothesis that address whether explaining (...) to others after initial studying surpasses restudying in learning performance, whether the amount of effort to retrieve to-be-taught information from memory moderates the learning effects of explaining to others, and whether the degree of elaboration during retrieval practice positively predicts the outcomes of learning by merely recalling to-be-taught information. Evidence is examined regarding whether each test is passed, and future directions for research on the retrieval practice hypothesis are discussed. (shrink)

『哲学探究』以後、最晩期に独立した地位を与える。ウィトゲンシュタインの知識の哲学。.

In lieu of an abstract, here is a brief excerpt of the content:Hume Studies Volume 29, Number 2, November 2003, pp. 205-221 The Origin of the Indirect Passions in the Treatise: An Analogy between Books 1 and 2 HARUKOINOUE 1. The Analogy Between Book 1 and Book 2 If the central design of the Treatise is to demonstrate that "the subjects of the Understanding and Passions make a complete chain of reasoning by themselves" (T 2; SBN xii), as Hume advertises, (...) it seems unquestionable that his intention lies in the illustration of the human mind as an integrated system dependent upon the cooperation of the understanding and the passions, which are discussed separately in Book 1 and Book 2, respectively.1 What is yet to be determined is whether any internal or systematic connection between these two books was originally intended by the author. Is it too fanciful to agree with John Passmore, and to suggest that some dynamic system of the human mind would emerge when we open the door which stands between the first two books?2 The key for this door seems to be found in Hume's account of personal identity. We may well remember how he distinguished two aspects of our identity, one regarding the understanding and another regarding the passions, and claimed that the latter "serves to corroborate" the former "by the making our distant perceptions influence each other, and by giving us a present concern for our past or future pains or pleasures" (T 1.4.6.19; SBN Haruko Inoue is Professor of Philosophy, Sapporo University 3-7-3-1 Toyohira-ku, Sapporo 062-8520, Japan. e-mail: [email protected] 206 Haruko Inoue 261). It seems reasonable to agree with Jane Mclntyre, who suggests that "Hume recognized questions about personal identity not addressed in Book 1, and that Book 2 makes an important contribution to our understanding of Hume's account of the self and its identity."3 And once we get a good understanding of this integrated mechanism of the human mind operating with both wheels, as it were, of the imagination and the passions, all we have to do is to accept his invitation and enjoy the efficiency of this two-wheeled car, driving through the fields of "Morals, Politics, and Criticism." For, if we take his words in his Advertisement seriously,4 it seems quite likely that the Treatise was published first as a set of Book 1 and Book 2, as Passmore suggests,5 and that Book 3 was written as the demonstration of the consistency of his system through the application of the hypothesis established in the first two books. This paper is a modest attempt to illustrate the intimate connection between Book 1 and Book 2: the latter, planned as a proof and reinforcement of the system Hume had established in Book 1, depends on the former. His basic strategy in the Treatise is to explain both systems of the mind by means of the easy transition of the imagination, which connects different perceptions with each other according to two kinds of principles or "properties of human nature " (T 2.1.4.2; SBN 283), viz. "the association both of impressions and ideas, and the mutual assistance they lend each other" (T 2.1.5.5; SBN 284). In Book 1 Hume establishes the system of the understanding in terms of the first association, viz. the association of ideas, and in Book 2 he proceeds to illustrate the system of passions by involving not only the second association but also the concurrence of both kinds of association which he calls "a double relation of impressions and ideas." His basic strategy is thus to apply the same method of reasoning to the illustration of both systems, assuming that "there is an attraction or association among impressions, as well as among ideas" (T 2.1.4.3; SBN 283). The intimate connection between the two systems of the understanding and the passions is illustrated through the demonstration of the "influence of the imagination upon the passions" (T 2.3.6.1; SBN 424), or in terms of the dependence of the latter on the former. It is owing to the dependence of the association of... (shrink)

descent represents a progression in this relationship whereby the Chorus, in finally abandoning their chariot and agreeing to approach Prometheus and listen to him, jeopardize their detachment from him and his fate, offer tentative support, and give him scope to develop his storytelling abilities and apply his persuasive powers. Although this progression does not represent an unequivocal commitment to Prometheus–for the Chorus fluctuate throughout the play between sympathy and reproach for him–it is none the less a crucial step as signalled (...) by the intensity of Prometheus' insistence that they descend and hear his story through to the end. (shrink)

The March 11, 2011, Great East Japan Earthquake caused extensive damage to the Tōhoku district of Japan and gave rise to many arguments concerning the meaning of “disaster” as well as the road to recovery. In particular, the severe accident of the Fukushima-Daiichi nuclear power plant reminded us of the overconfidence of science and technology. In this article, I will discuss concepts such as “disaster of civilization,” “impermanence,” “betweenness,” and the double structure of the Japanese view of nature.

It has been suggested that preparing to teach and teaching are conditionally effective in enhancing one’s own learning. This paper focuses on interactivity—the level of teacher-student interaction in expected or actual teaching—as the potential key to understanding and controlling the variability in the effectiveness of learning by preparing to teach and teaching. By summarizing and reanalyzing the results of previous studies, I suggest that the learning benefits of studying with the expectation of direct teaching (i.e., teaching a student face-to-face) are (...) greater than those of studying with the expectation of indirect teaching (i.e., teaching a student indirectly by creating a lecture video, providing written explanations, or using other means) and that learning by direct teaching surpasses learning by explaining to oneself or indirect teaching at least after preparing to do so. Next, three candidate explanations for the impact of interactivity are discussed: the advantages of asking and answering questions, obtaining additional information about and from one’s student, and enhancing one’s motivation to process learning material deeply while preparing to teach and teaching. Finally, I conclude with the remaining questions and directions for future research. (shrink)

明治の世には、西欧的近代化の流れの中にあっても「日本人としての矜持と風格」といったものがあった。それはいわば凜乎とした倫理意識と、土着的な共同体意識である。それらは漢籍の教養に裏打ちされた至高なる精神 性であったと言ってよい。明治は、思想・文化の面において、日本の精神史上、「豊饒の時代」であった。.

Journal of Political Philosophy, Volume 30, Issue 3, Page 370-394, September 2022.

In this article, I argue that Powers and Faden’s non-ideal, comprehensive theory of justice cannot keep in line with the proposed moderateness of their essentialist approach. My argument is as follows: Powers and Faden’s comprehensive theory of justice contravenes the thrust of moderate essentialism, in claiming that their theory values health for its own sake. Why do they define their conception of justice as valuing health for its own sake when it is likely to be incongruous with their essentialist approach? (...) To understand this, we should examine their sufficientarian proposal. There are two requirements for plausible sufficientarianism. The first requirement is to specify the threshold below which people are seriously deprived and must be urgently benefited in a non-arbitrary manner. The second requirement is that sufficientarianism should be sensitive to certain inequalities above the threshold. Powers and Faden’s approach convincingly meets the first requirement. However, the non-ideal aspect of their approach, which is key to meeting the second requirement, makes it explicit that at least one of the listed dimensions of well-being must be valued for their own sake. This is not reconcilable with their own characterization of moderate essentialism. For this reason, we should conclude that Powers and Faden fail to argue for moderate essentialism. (shrink)

The harshness objection is the most important challenge to luck egalitarianism. Very recently, Andreas Albertsen and Lasse Nielsen provided a scrupulous analysis of the harshness objection and claim that only the inconsistency objection—the objection that luck egalitarianism is incompatible with the ideal of basic moral equality—has real bite. I argue that the relevantly construed incoherence objection is not as strong as Albertsen and Nielsen believe. In doing so, first, I show that the deontological luck egalitarian conception of equal treatment does (...) not endorse harsh policies such as excessive responsibility-sensitive healthcare that would be disrespectful to the imprudent. Second, I demonstrate that deontological luck egalitarianism is not troubled by the case that involves a lack of respect for the prudent, which vexes Anderson’s relational egalitarianism that Kasper Lippert-Rasmussen’s argument highlights. I thus claim that the harshness objection is not a truly decisive objection against the luck egalitarian project. (shrink)

descent represents a progression in this relationship whereby the Chorus, in finally abandoning their chariot and agreeing to approach Prometheus and listen to him, jeopardize their detachment from him and his fate, offer tentative support, and give him scope to develop his storytelling abilities and apply his persuasive powers. Although this progression does not represent an unequivocal commitment to Prometheus–for the Chorus fluctuate throughout the play between sympathy and reproach for him–it is none the less a crucial step as signalled (...) by the intensity of Prometheus' insistence that they descend and hear his story through to the end. (shrink)

In this paper, we shall give another proof of the faithfulness of Blass translation of the propositional fragment \ of Leśniewski’s ontology in the modal logic \ by means of Hintikka formula. And we extend the result to von Wright-type deontic logics, i.e., ten Smiley-Hanson systems of monadic deontic logic. As a result of observing the proofs we shall give general theorems on the faithfulness of B-translation with respect to normal modal logics complete to certain sets of well-known accessibility relations (...) with a restriction that transitivity and symmetry are not set at the same time. As an application of the theorems, for example, B-translation is faithful for the provability logic \ ), that is, \ \ \ \supset \Box \phi \). The faithfulness also holds for normal modal logics, e.g., \, \, \, \. We shall conclude this paper with the section of some open problems and conjectures. (shrink)

The question of the existence of cultural universals immediately leads us to the problem of intercultural communication and of so-called incommensurability. Over the last few decades, these topics have been the subject of controversy in the philosophy of science, and the stock of universalism has been falling as a result of the rise of Kuhn’s paradigm theory and Quine’s thesis of the indeterminacy of translation. Nowadays cultural pluralism or relativism is rather dominant among philosophers and has begun to appear plausible, (...) too, from an anthropological or sociological point of view. But philosophically, as is well known, relativism harbors many difficulties and paradoxes. As philosophers, therefore, we cannot accept imprudent relativism just as it is. (shrink)