In April 2020, almost six out of 10 people around the world were in lockdown due to the COVID-19 pandemic. Being locked down usually has a deleterious effect on the confined individual's mental health. In this exceptionally challenging context, finding ways to minimize negative mood about the pandemic is essential. Pandemic-related negative states (“negative mood”) and recovery experiences were investigated in a sample of 264 individuals who completed daily surveys four times per day over 7 consecutive days. MSEMs analyses revealed (...) that negative mood persisted from moment-to-moment through the day, thus showing a response lag effect. Further analyses revealed that when someone experienced pandemic-related psychological detachment, relaxation, mastery, control, pleasure, or relatedness at specific periods of the day, mood had improved at the next measured time period, suggesting a protective effect. However, the pattern displayed by singles with dependents suggests that some recovery experiences at specific periods during the day seem to have a backfiring effect and worsen subsequent mood. These findings bring new insight into the role of recovery experiences during lockdowns and suggest that many could benefit from such experiences throughout the day when self-isolating. However, for individuals with multiple risk factors such as being single with dependents, some recovery experiences, at specific periods during the day, might not bring the desired outcome and future research is needed to examine if guilt or domestic burden may explain this finding. Results contribute to our understanding of how to take care of one's mental health during the current pandemic, and concrete recommendations adapted to individual contexts are provided. (shrink)

Aworkshop was held August 26–28, 2015, by the Earth- Life Science Institute (ELSI) Origins Network (EON, see Appendix I) at the Tokyo Institute of Technology. This meeting gathered a diverse group of around 40 scholars researching the origins of life (OoL) from various perspectives with the intent to find common ground, identify key questions and investigations for progress, and guide EON by suggesting a roadmap of activities. Specific challenges that the attendees were encouraged to address included the following: What key (...) questions, ideas, and investigations should the OoL research community address in the near and long term? How can this community better organize itself and prioritize its efforts? What roles can particular subfields play, and what can ELSI and EON do to facilitate research progress? (See also Appendix II.) The present document is a product of that workshop; a white paper that serves as a record of the discussion that took place and a guide and stimulus to the solution of the most urgent and important issues in the study of the OoL. This paper is not intended to be comprehensive or a balanced representation of the opinions of the entire OoL research community. It is intended to present a number of important position statements that contain many aspirational goals and suggestions as to how progress can be made in understanding the OoL. The key role played in the field by current societies and recurring meetings over the past many decades is fully acknowledged, including the International Society for the Study of the Origin of Life (ISSOL) and its official journal Origins of Life and Evolution of Biospheres, as well as the International Society for Artificial Life (ISAL). (shrink)

AbstractmRNA stability is increasingly recognized as being essential for controlling the expression of a wide variety of transcripts during neuronal development and synaptic plasticity. In this context, the role of AU‐rich elements (ARE) contained within the 3′ untranslated region (UTR) of transcripts has now emerged as key because of their high incidence in a large number of cellular mRNAs. This important regulatory element is known to significantly modulate the longevity of mRNAs by interacting with available stabilizing or destabilizing RNA‐binding proteins (...) (RBP). Thus, in parallel with the emergence of ARE, RBP are also gaining recognition for their pivotal role in regulating expression of a variety of mRNAs. In the nervous system, the member of the Hu family of ARE‐binding proteins known as HuD, has recently been implicated in multiple aspects of neuronal function including the commitment and differentiation of neuronal precursors as well as synaptic remodeling in mature neurons. Through its ability to interact with ARE and stabilize multiple transcripts, HuD has now emerged as an important regulator of mRNA expression in neurons. The present review is designed to provide a comprehensive and updated view of HuD as an RBP in the nervous system. Additionally, we highlight the role of HuD in multiple aspects of a neuron's life from early differentiation to changes in mature neurons during learning paradigms and in response to injury and regeneration. Finally, we describe the current state of knowledge concerning the molecular and cellular events regulating the expression and activity of HuD in neurons. BioEssays 28: 822–833, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

Philosophers of mind and language who advance causal theories face a sort of conjunction problem. When we say that the thing had in mind or the thing referred to is a matter of what causally impacted the thinker or speaker, we must somehow narrow down the long conjunction of items in a causal chain, all of which contributed to the having in mind, but only one of which becomes the object of thought or the linguistic referent. Here, I sketch a (...) notion of cognitive focus intended to do this narrowing. The notion borrows three key aspects from visual focus and some technological aides—causation, amplification, and suppression. I suggest a broader application of this framework to address the conjunction problem not only in ordinary contexts of perceptual focus but also in evidence cases involving non-perceptual cognitive focus. I further suggest cognitive focus is helpful in distinguishing referential vs. attributive thought. (shrink)

Comment et en quoi les études sur le genre permettent de retravailler les disciplines scientifiques? Comment la pré-valence de l'androcentrisme des sciences crée des apories au sein des connaissances scientifiques? En quoi le prisme du genre peut-il requestionner les pratiques scientifiques, particulièrement au sein des sciences dites 'dures' et expérimentales? En quoi le genre permet aussi de renouveler ler l'appréhension des pratiques militantes et professionnelles? et ouvrage s'intéresse aux apports du genre, un concept u des sciences humaines et sociales qui (...) tend à s'appliqu r à la réflexion scientifique menée au sein d'autres mondes de la recherche. Cette inclusion permet de pointer les écueils, dans des domaines scientifiques longtemps restés hermétiques aux enjeux du genre. Il rend compte de travaux récents questionnant les enjeux épistémologiques de la critique féministe des sciences, mais aussi portant sur les questions d'identité de genre ainsi que de santé et de contrôle de la sexualité. II réunit des recherches inédites émanant de diverses disciplines scientifiques : pharmacologie, physiologie, biologie, toxicologie, mais aussi sociologie, anthropologie, histoire, droit et philosophie, présentées par des spécialistes des sciences sociales et des études de genre comme par des Fornnières et pionniers ayant relevé le challenge de croiser s enjeux de genre à des objets de recherche nouveaux. Son originalité tient également à l'apport de réflexions croisées sur les enjeux contemporains du genre émanant des pratiques ancrées sur les terrains militants et professionnels."--Page 4 of cover. (shrink)

A presence for decades in individuals’ everyday life practices and identity formation, the Walt Disney Company has more recently also become an influential element within the "big" curriculum of public and private spaces outside of yet in proximity to formal educational institutions. _Disney, Culture, and Curriculum_ explores the myriad ways that Disney’s curricula and pedagogies manifest in public consciousness, cultural discourses, and the education system. Examining Disney’s historical development and contemporary manifestations, this book critiques and deconstructs its products and perspectives (...) while providing insight into Disney’s operations within popular culture and everyday life in the United States and beyond. The contributors engage with Disney’s curricula and pedagogies in a variety of ways, through critical analysis of Disney films, theme parks, and planned communities, how Disney has been taught and resisted both in and beyond schools, ways in which fans and consumers develop and negotiate their identities with their engagement with Disney, and how race, class, gender, sexuality, and consumerism are constructed through Disney content. Incisive, comprehensive, and highly interdisciplinary, _Disney, Culture, and Curriculum_ extends the discussion of popular culture as curriculum and pedagogy into new avenues by focusing on the affective and ontological aspects of identity development as well as the commodification of social and cultural identities, experiences, and subjectivities. (shrink)

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An important milestone was crossed recently in the discipline of philosophy, but hardly anyone seems to have noticed. In 2004, for the first time since statistics have been gathered on such things, women earned more than 30 percent of the doctorates in philosophy in this country, 33.3 percent, up from 27.1 percent the year before. The highest percentage women had achieved previously in philosophy was 29.4 percent, in..

In Anti‐Oedipus, Deleuze and Guattari aim to describe schizophrenia in a positive manner. According to them, the schizophrenic lives on the intensive order. To fully comprehend what this means, it is key to address some of Deleuze's insights regarding the notion of intensity in relation to experience and cognition. This is why I will combine ideas from Anti‐Oedipus with theory from Difference and Repetition, in order to explain Deleuze and Guattari's conception of intensity in its relation to common sense and (...) to schizophrenia. According to this conception (a), intensity is the condition of possibility and limit for the sensible; (b) it becomes covered over by the organizing principles of common sense, which make our affects more workable and recognizable; and (c) this process of organization must hang together with the codification of desire through Oedipus, the main organizational principle of the socius. On the back of these theoretical considerations, I will explain what it means to say that the schizophrenic lives amongst intensities: (a) this involves a lack of codification of desire and thus of common sense, meaning an absence of organizational principles; and (b) this perspective leads to a different understanding of the schizophrenic's experience and expression, with very concrete implications for a clinical approach to schizophrenia. (shrink)

I take it as given that we manage to linguistically refer to objects we can neither perceive nor uniquely describe. Kripke accounts for this fact by appeal to causal-historical chains of communication. But Evans famously presented what has seemed to many a devastating counterexample to Kripke’s view: the phenomenon of reference-shifting. Here, I’ll agree with critics that Kripke’s view is insufficient to handle cases of reference shift, but I’ll argue for an alternative version of the causal-historical account that is immune (...) to Evans’ counterexample. The key move will be at the foundations; it will require a change in what it is we’re giving a causal-historical account of. Critically, I’ll argue that we should reject two claims associated with the causal-historical picture. First, we should reject the claim that names are used to think of their referents. Second, we should reject the claim that later speakers defer to earlier ones. (shrink)

This experiment uses quantitative and qualitative measures to address the effect of two syllabus statements on academic misconduct: one based on prohibitions and one on academic integrity. Students expressed favorable attitudes toward the statements, showed an increase in guilt compared to a control group, but showed no decrease in intentions to cheat. Including only a standard academic misconduct statement in one's syllabus is not sufficient to alter behavior, which should be acknowledged by faculty.

The rediscovery of Aristotle’s works on syllogisms in the Latin world, especially the Sophistici Elenchi and then the Prior Analytics, gave rise to sophisticated views on the nature of syllogistic form and syllogistic matter in the thirteenth century. It led to debates on the ontology of the syllogism as studied in the Prior Analytics, i.e. the syllogism made of letters and the four logical constants a/e/i/o, with deep consequences on the definition of logic as a universal method for all sciences (...) and as a science itself. (shrink)

Les théories contractualistes de l’âge classique se fondent sur la conception d’un état de nature qui devient, à cause de ses contradictions internes, un état de guerre auquel il faut remédier par un artifice rationnel, le pacte. Alors même que ces contradictions sont issues des passions humaines, celles-ci semblent impensables dans le cadre purement juridique de ces théories, où ne sont analysés ni les mécanismes passionnels d’adhésion au politique, ni la menace de dissolution de l’État. Nous nous attachons à comparer (...) le rôle que Hobbes et Spinoza font jouer aux passions dans l’élaboration de leurs doctrines politiques : tandis que Hobbes témoigne d’un souci constant des passions, tout en les mettant à l’écart lorsqu’il s’agit de penser la construction et le fonctionnement de l’édifice politique, Spinoza permet de penser deux groupes de passions – celles qui résistent nécessairement au corps politique et celles qui lui font obstacle ponctuellement. Ces dernières constituent tout à la fois des facteurs de décomposition et de recomposition du corps collectif. Cette approche du politique à partir des causes de sa dissolution permet d’apporter un éclairage à la signification du droit naturel moderne tel qu’il se construit chez Hobbes et chez Spinoza. (shrink)

IntroductionMilitary personnel and Veterans are at increased risk of mental and physical health conditions, which can impact their families. Spouses often perform a vital role in caring for service members and Veterans facing illness or injury, which can lead to caregiver burden. In turn, this may contribute to relationship issues. Research suggests that ensuring that spouses are well supported can alleviate some of these negative effects. The current study examined whether social support received by spouses of newly released Veterans buffers (...) the impact of Veterans’ health on caregiver burden, subsequently impacting spouses’ relationship satisfaction.MethodsData were collected as part of the Canadian Armed Forces Transition and Well-being Survey. The sample included N = 595 spouses of Regular Force Veterans who released in 2016 with at least 2 years of service. We examined Veterans’ mental and physical health and spouses’ caregiver burden, social support, and relationship satisfaction. A moderated mediation model was tested using structural equation modeling.ResultsThere was a significant indirect association between Veterans’ health and spouses’ relationship satisfaction through caregiver burden. Furthermore, social support moderated the association, as evidenced by a weaker association between Veterans’ health and caregiver burden at low levels of social support compared to high levels.ImplicationsFindings suggest additional efforts should be made to ensure sufficient support is provided to spouses, especially when they are caring for a service member or Veteran facing illness or injury, to strengthen their families’ well-being. (shrink)

Although I am not supposed to have a favorite patient, she is one. Arissa is a three‐year‐old girl. Her parents, natives of Comoros, had illegally immigrated to the French department of Mayotte. When I first began treating her, I saw her as a time bomb. But we built a relationship, and when she deteriorated on my watch, I wanted to say, “Fight to the end!—she is my favorite patient!” But I thought that I did not have the necessary distance to (...) answer the question. (shrink)

We expand on the article “Ethical Challenges Arising in the COVID-19 Pandemic: An Overview from the Association of Bioethics Program Directors (ABPD) Task Force” to consider the ways in which rural...

_Expanding Curriculum Theory, Second Edition_ carries through the major focus of the original volume—to reflect on the influence of Deleuze and Guattari’s concept of "lines of flight" and its application to curriculum theorizing. What is different is that the lines of flight have since shifted and produced expanded understandings of this concept for curriculum theory and for education in general. This edition reflects the impact of events that have contributed to this shift, in particular the logic of school policy changes (...) and reforms in the past decade, and the continued explosion of social media and its effect on the collective understanding of how both "knowledge" and "education" work as forms of repression. The introduction updates the text and puts it into current debates in the field and in the larger socio-economic milieu. New dis/positions are presented that explore central questions circulating within and outside curriculum studies. Exciting scholarship on a range of topics includes notions of desire and commodities, youth culture and violence, new directions in curriculum theory, Eco-Ethical consciousness, new Deleuzian views of normality, the diffusion of technology and lines of flight in transnational curriculum inquiry. (shrink)

Qu'entendre par modernité? Résulte-t-elle d'une transposition des schèmes théologiques et des dispositifs théologico-politiques propres au christianisme médiéval, ou bien s'est-elle affirmée contre son propre passé théologique, en rupture avec les formes héritées du passé? Et comment situer, dans ce processus, les philosophies de Hobbes et de Spinoza, comprises tantôt comme héritières des théologies de la toute-puissance divine, de l'augustinisme ou de la Réforme, tantôt comme inaugurant le.

This article discusses the discourses of disability through a parallel `disabling' of its own text. It draws on literary as well as sociological sources in order to interrogate the nature and relations of the `tragic', the `heroic' and the `comic'. The authors offer the conclusion that the comic is never quite absent from the discourse of tragedy (after Kundera), and turn that insight back on their own text, in an attempt to refuse the solemnities and closures of their own narrative.

Surprise – these much-publicized rules are not the least bit reassuring to people who specialize in the study of ethics. While attention to ethics is certainly welcome, these ethical codes provide a too-easy cop-out, a way to neatly dispose of attention to nagging and pervasive problems. The typical professional code is little more than a checklist of rules that enables professionals of any stripe to give lip service to ethical behavior without engaging in continuing dialogue on ethical dilemmas. Neatly packaged (...) commandments short-circuit development of the reasoning tools to work through ethical challenges meaningfully and with long-lasting impact on the actual behavior in any field. (shrink)

The U.S. Supreme Court recently held that a parody by the rap group 2 Live Crew of Ray Orbison's song "Oh, Pretty Woman" was "fair use" and thus did not infringe the copyright. Although the court insisted that it was not evaluating the quality of the parody, I argue that it does in fact make several aesthetic evaluations and sometimes even seems to praise the content of the parody. I first consider the stated reasons for the claimed refusal of the (...) court to evaluate aesthetic quality. Second, I examine the evaluations which the court in fact does make, at least some of which are clearly aesthetic evaluations. I then argue that aesthetic value judgments are both necessary and possible for determinations of "fair use" for such works as the "Pretty Woman" parody. (shrink)

The most popular form of reversible contraception in the United States is the female-controlled hormonal birth control pill. Consequently, scholars and lay people have typically assumed that women take primary responsibility for contraceptive decision making in relationships. Although many studies have shown that men exert strong influence in couple’s contraceptive decisions in developing countries, very few studies have considered the gendered dynamic of contraceptive decision making in developed societies. This study uses in-depth interviews with 30 American opposite-sex couples to show (...) that contraceptive responsibility in long-term relationships in the United States often conforms to a gendered division of labor, with women primarily in charge. A substantial minority of men in this study were highly committed contraceptors. However, the social framing of contraception as being primarily in women’s “sphere,” and the technological constraints on their participation, made even these men reluctant to discuss contraception with their women partners. (shrink)

Past research finds that after menopause some women experience negative changes such as vaginal dryness, decreased libido, and decreased orgasm quality; very little research inquires about positive changes. In contrast, this study shifts the research focus from whether women experience menopausal changes to how women view any changes in sex life. Based on 30 in-depth interviews with heterosexual and lesbian women, the author finds that most women emphasize cultural and social issues, such as relationship status and quality, health, and sexual (...) history, rather than menopausal changes when they describe sex after menopause. However, she finds a difference by sexual orientation in how women handle problems in sex. The author concludes by discussing the implication of this research for future menopause and sex research; most important, she emphasizes studying sex in the context of women's lives rather than as a result of the biological changes of menopause. (shrink)

Je distingue successivement trois modes d’incertitude en psychanalyse. L’incertitude caractérise d’abord la progressive connaissance d’un cas qui se présente au connaître comme une énigme et qu’il s’agit de construire comme singulier. L’incertitude de la connaissance tient ensuite à l’alliance très particulière du savoir et du non savoir dans la pratique et la théorie de la psychanalyse. Elle tient enfin à la mise au point d’une nouvelle définition du champ même auquel la psychanalyse a affaire : un certain régime des actes (...) dans l’existence humaine qui s’annonce dans le phénomène clinique de la répétition et qui caractérise le pulsionnel comme un « morceau d’activité » à l’œuvre dans la transposition des impasses de la vie pulsionnelle, c’est-à-dire des symptômes par transposition dans le site construit par la cure. (shrink)

David-Ménard examines the problem of the genesis of Kant's moral philosophy. The separation between Kantian practical reason and the inclinations of sense which it regulates is shown by the author to originate in Kant's attempt to regulate his own tendency to hypochondria. Her argument links the themes from two of Kant's precritical works which attest to this tendency-"An Essay on the Maladies of the Mind" and Observations on the Feeling of the Beautiful and the Sublime-to the final form of (...) the critical philosophy. (shrink)