In April 2020, almost six out of 10 people around the world were in lockdown due to the COVID-19 pandemic. Being locked down usually has a deleterious effect on the confined individual's mental health. In this exceptionally challenging context, finding ways to minimize negative mood about the pandemic is essential. Pandemic-related negative states (“negative mood”) and recovery experiences were investigated in a sample of 264 individuals who completed daily surveys four times per day over 7 consecutive days. MSEMs analyses revealed (...) that negative mood persisted from moment-to-moment through the day, thus showing a response lag effect. Further analyses revealed that when someone experienced pandemic-related psychological detachment, relaxation, mastery, control, pleasure, or relatedness at specific periods of the day, mood had improved at the next measured time period, suggesting a protective effect. However, the pattern displayed by singles with dependents suggests that some recovery experiences at specific periods during the day seem to have a backfiring effect and worsen subsequent mood. These findings bring new insight into the role of recovery experiences during lockdowns and suggest that many could benefit from such experiences throughout the day when self-isolating. However, for individuals with multiple risk factors such as being single with dependents, some recovery experiences, at specific periods during the day, might not bring the desired outcome and future research is needed to examine if guilt or domestic burden may explain this finding. Results contribute to our understanding of how to take care of one's mental health during the current pandemic, and concrete recommendations adapted to individual contexts are provided. (shrink)

Aworkshop was held August 26–28, 2015, by the Earth- Life Science Institute (ELSI) Origins Network (EON, see Appendix I) at the Tokyo Institute of Technology. This meeting gathered a diverse group of around 40 scholars researching the origins of life (OoL) from various perspectives with the intent to find common ground, identify key questions and investigations for progress, and guide EON by suggesting a roadmap of activities. Specific challenges that the attendees were encouraged to address included the following: What key (...) questions, ideas, and investigations should the OoL research community address in the near and long term? How can this community better organize itself and prioritize its efforts? What roles can particular subfields play, and what can ELSI and EON do to facilitate research progress? (See also Appendix II.) The present document is a product of that workshop; a white paper that serves as a record of the discussion that took place and a guide and stimulus to the solution of the most urgent and important issues in the study of the OoL. This paper is not intended to be comprehensive or a balanced representation of the opinions of the entire OoL research community. It is intended to present a number of important position statements that contain many aspirational goals and suggestions as to how progress can be made in understanding the OoL. The key role played in the field by current societies and recurring meetings over the past many decades is fully acknowledged, including the International Society for the Study of the Origin of Life (ISSOL) and its official journal Origins of Life and Evolution of Biospheres, as well as the International Society for Artificial Life (ISAL). (shrink)

Non-epistemic values pervade climate modelling, as is now well documented and widely discussed in the philosophy of climate science. Recently, Parker and Winsberg have drawn attention to what can be termed “epistemic inequality”: this is the risk that climate models might more accurately represent the future climates of the geographical regions prioritised by the values of the modellers. In this paper, we promote value management as a way of overcoming epistemic inequality. We argue that value management can be seriously considered (...) as soon as the value-free ideal and inductive risk arguments commonly used to frame the discussions of value influence in climate science are replaced by alternative social accounts of objectivity. We consider objectivity in Longino's sense as well as strong objectivity in Harding's sense to be relevant options here, because they offer concrete proposals that can guide scientific practice in evaluating and designing so-called multi-model ensembles and, in fine, improve their capacity to quantify and express uncertainty in climate projections. (shrink)

Philosophers of mind and language who advance causal theories face a sort of conjunction problem. When we say that the thing had in mind or the thing referred to is a matter of what causally impacted the thinker or speaker, we must somehow narrow down the long conjunction of items in a causal chain, all of which contributed to the having in mind, but only one of which becomes the object of thought or the linguistic referent. Here, I sketch a (...) notion of cognitive focus intended to do this narrowing. The notion borrows three key aspects from visual focus and some technological aides—causation, amplification, and suppression. I suggest a broader application of this framework to address the conjunction problem not only in ordinary contexts of perceptual focus but also in evidence cases involving non-perceptual cognitive focus. I further suggest cognitive focus is helpful in distinguishing referential vs. attributive thought. (shrink)

Convergence of model projections is often considered by climate scientists to be an important objective in so far as it may indicate the robustness of the models’ core hypotheses. Consequently, the range of climate projections from a multi-model ensemble, called “model spread”, is often expected to reduce as climate research moves forward. However, the successive Assessment Reports of the Intergovernmental Panel on Climate Change indicate no reduction in model spread, whereas it is indisputable that climate science has made improvements in (...) its modelling. In this paper, after providing a detailed explanation of the situation, we describe an epistemological setting in which a steady model spread is not doomed to be seen as negative, and is indeed compatible with a desirable evolution of climate models taken individually. We further argue that, from the perspective of collective progress, as far as the improvement of the products of a multi-model ensemble is concerned, reduction of model spread is of lower priority than model independence. (shrink)

Individuals often face administrative hurdles in attempting to access health care, public programmes, and other legal statuses and entitlements. These ordeals are the products, directly or indirectly, of institutional and policy design choices. I argue that evaluating whether such ordeals are justifiable or desirable instruments of social policy depends on assessing, beyond their targeting effects, the process-related burdens they impose on those attempting to navigate them and these burdens’ distributive effects. I here examine specifically how ordeals that levy time costs (...) reduce and constrain individuals’ free time, and how such time-cost ordeals may thereby create, deepen and compound disadvantages. (shrink)

This paper is the first of two in a series. In this paper, we identify mental health needs and challenges in the age of COVID-19 among Nepali-speaking, Bhutanese resettled refugees in the USA. We argue for a public health justice framework that looks critically at social determinants impacting mental health (SDIMH) barriers, which negatively impact our Bhutanese population, and serves as a theoretical foundation toward public policy and law that will inform healthcare decisions and fair treatment of resettled refugees at (...) the clinical bedside and in the community. We first describe our Bhutanese refugee population and the critical mental health issues that, for many, originated during political persecution and violent ethnic cleansing initiatives, or while living in refugee camps prior to resettlement to the USA. We present a social justice framework emerging from an extensive literature review and incorporating core social determinants specific to mental health in the age of COVID-19, which are guided by the social determinants of economic stability; neighborhoods and physical environment; education; nutrition and exercise; community and social context; healthcare system; and legal system. We illustrate specific SDIMH of our resettled Bhutanese refugees during the pandemic, followed by a second paper that details recommendations for applying the SDIMH in a collective effort to address specific barriers to mental healthcare and support. (shrink)

AbstractmRNA stability is increasingly recognized as being essential for controlling the expression of a wide variety of transcripts during neuronal development and synaptic plasticity. In this context, the role of AU‐rich elements (ARE) contained within the 3′ untranslated region (UTR) of transcripts has now emerged as key because of their high incidence in a large number of cellular mRNAs. This important regulatory element is known to significantly modulate the longevity of mRNAs by interacting with available stabilizing or destabilizing RNA‐binding proteins (...) (RBP). Thus, in parallel with the emergence of ARE, RBP are also gaining recognition for their pivotal role in regulating expression of a variety of mRNAs. In the nervous system, the member of the Hu family of ARE‐binding proteins known as HuD, has recently been implicated in multiple aspects of neuronal function including the commitment and differentiation of neuronal precursors as well as synaptic remodeling in mature neurons. Through its ability to interact with ARE and stabilize multiple transcripts, HuD has now emerged as an important regulator of mRNA expression in neurons. The present review is designed to provide a comprehensive and updated view of HuD as an RBP in the nervous system. Additionally, we highlight the role of HuD in multiple aspects of a neuron's life from early differentiation to changes in mature neurons during learning paradigms and in response to injury and regeneration. Finally, we describe the current state of knowledge concerning the molecular and cellular events regulating the expression and activity of HuD in neurons. BioEssays 28: 822–833, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

In this article I examine the view, common amongst several contemporary legal positivists, that rules of recognition are to be understood as conventional rules of some kind. The article opens with a discussion of H.L.A. Hart's original account of the rule of recognition in the 1st edn of The Concept of Law and argues that Hart did not view the rule of recognition as a conventional rule in that account. I then discuss Hart's apparent turn towards a conventionalist understanding of (...) the rule of recognition in the ‘Postscript’ to the 2nd edn of The Concept of Law, and attempt to cast doubt on the strength of Hart's commitment to such a turn, and on the reasons prompting him to make it. Finally, I consider one of the most interesting contemporary conventionalist accounts of rules of recognition, namely Andrei Marmor's view that such rules should be understood as the constitutive conventions of partly autonomous social practices. My aim in this part of the article is to compare Marmor's account with my earlier interpretation of Hart's views, and to consider whether Marmor's account truly is conventionalist in character and whether it provides us with a persuasive conventionalist understanding of rules of recognition. (shrink)

Background: Research Ethics Committees (RECs) or their equivalent review applications for prospective research with human participants. Reviewers use universally agreed principles i to make decisions about whether prospective health and social care research is ethical. Close attention to understanding how reviewers go about their decision-making work and consider principles in practice is limited. Objective: The study aimed to understand how reviewers made decisions in the contexts of meetings and to understand more about how reviewers approach their work. The purpose of (...) this article is to draw on data and findings and to show how reflective equilibrium as a theoretical frame can (1) deepen understanding of ethics review and (2) permit a reflexive examination of the habitual processes of review. Design and participants: Methods captured the day-to-day work of the RECs. Seventeen applications were heard during eight observations. There were 12 formal interviews with reviewers (n = 12) and with researchers (n = 8) which are not reported on in this article. Ethical considerations: Organisational permission for the study was given by the National Research Ethics Service (NRES) whose functions became part of the Health Research Authority (HRA) during the study. The study was given favourable opinion by the University of Salford's REC (Reference HSCR11/17). Findings: Data were analysed using constructed grounded theory resulting in eight themes which revealed attention to procedure and engagement with applications. Reflective equilibrium was used as a qualitative frame to interpret themes distilling them into three processes at work in review: emotion and intuition; imagination and creative thinking; and intuition and trust. Discussion: Reviewers went back and forth between universal principles and considered these in the contexts of each application using the above processes. Conclusions: Reflective equilibrium offers a coherent and grounded account of review work. Reflexivity in training for reviewers is essential for improving practices. The challenges reflexivity presents can be assisted by using reflective equilibrium as a tool to illuminate tacit review processes. (shrink)

Comment et en quoi les études sur le genre permettent de retravailler les disciplines scientifiques? Comment la pré-valence de l'androcentrisme des sciences crée des apories au sein des connaissances scientifiques? En quoi le prisme du genre peut-il requestionner les pratiques scientifiques, particulièrement au sein des sciences dites 'dures' et expérimentales? En quoi le genre permet aussi de renouveler ler l'appréhension des pratiques militantes et professionnelles? et ouvrage s'intéresse aux apports du genre, un concept u des sciences humaines et sociales qui (...) tend à s'appliqu r à la réflexion scientifique menée au sein d'autres mondes de la recherche. Cette inclusion permet de pointer les écueils, dans des domaines scientifiques longtemps restés hermétiques aux enjeux du genre. Il rend compte de travaux récents questionnant les enjeux épistémologiques de la critique féministe des sciences, mais aussi portant sur les questions d'identité de genre ainsi que de santé et de contrôle de la sexualité. II réunit des recherches inédites émanant de diverses disciplines scientifiques : pharmacologie, physiologie, biologie, toxicologie, mais aussi sociologie, anthropologie, histoire, droit et philosophie, présentées par des spécialistes des sciences sociales et des études de genre comme par des Fornnières et pionniers ayant relevé le challenge de croiser s enjeux de genre à des objets de recherche nouveaux. Son originalité tient également à l'apport de réflexions croisées sur les enjeux contemporains du genre émanant des pratiques ancrées sur les terrains militants et professionnels."--Page 4 of cover. (shrink)

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This paper is the second of two in a series. In our first paper, we presented a social justice framework emerging from an extensive literature review and incorporating core social determinants specific to mental health in the age of COVID-19 and illustrated specific social determinants impacting mental health (SDIMH) of our resettled Bhutanese refugee population during the pandemic. This second paper details specific barriers to the SDIMH detrimental to the basic human rights and social justice of this population during this (...) pandemic. The SDIMH, as described, further informs the need for social justice measures and cultural humility in mental healthcare, public health, law, and community engagement. This work concludes with a proposed call to action toward mental health improvement and fair treatment for refugee populations in three core areas: communication and education, social stigma and discrimination, and accessibility and availability of resources. (shrink)

A presence for decades in individuals’ everyday life practices and identity formation, the Walt Disney Company has more recently also become an influential element within the "big" curriculum of public and private spaces outside of yet in proximity to formal educational institutions. _Disney, Culture, and Curriculum_ explores the myriad ways that Disney’s curricula and pedagogies manifest in public consciousness, cultural discourses, and the education system. Examining Disney’s historical development and contemporary manifestations, this book critiques and deconstructs its products and perspectives (...) while providing insight into Disney’s operations within popular culture and everyday life in the United States and beyond. The contributors engage with Disney’s curricula and pedagogies in a variety of ways, through critical analysis of Disney films, theme parks, and planned communities, how Disney has been taught and resisted both in and beyond schools, ways in which fans and consumers develop and negotiate their identities with their engagement with Disney, and how race, class, gender, sexuality, and consumerism are constructed through Disney content. Incisive, comprehensive, and highly interdisciplinary, _Disney, Culture, and Curriculum_ extends the discussion of popular culture as curriculum and pedagogy into new avenues by focusing on the affective and ontological aspects of identity development as well as the commodification of social and cultural identities, experiences, and subjectivities. (shrink)

Axel Honneth distinguishes between recognitive practices according to the social domain in which they occur and this allows him to theorise the relationship between power and recognition. 'Love-based recognition', which suggests the centrality of recognition to the relationships that nurture us in the first instance, is located in the family. Honneth argues that relationships encompassed by this category are pre-political, thereby repeating the distinction between the public and the private common to much political theory. This article explores the structure of (...) this delineation in his thinking. I argue that Honneth's analysis marginalises feminist concerns with how power functions through recognition in the private sphere. Honneth also robs himself of a rejoinder to recognition sceptics, who suggest that the desire for recognition is a condition of subordination. The article argues for an alternative approach to the analysis of 'love' within recognitive theory. © 2010 Macmillan Publishers Ltd. (shrink)

This article proposes that the French performance artist Orlan, has, by undertaking a series of surgical interventions on her face and body, radically challenged current standards of beauty. By engaging with Judeo-Christian iconography, Greek mythology and French literature in her operations/performances, she has established an oeuvre that aligns her not only with corporeality and the abject body through images of the sacrificial, but also with aberrant body forms associated with the carnival. Although seduced by the rhetoric that surrounds the body (...) in technology, she has turned to excess as a strategy against the benign and controlled nature of the screen, and the media's homogenization of body images. Her new identity, although not extreme, is a site of resistance in a society bent on eliminating forms that threaten the status quo. (shrink)

The rediscovery of Aristotle’s works on syllogisms in the Latin world, especially the Sophistici Elenchi and then the Prior Analytics, gave rise to sophisticated views on the nature of syllogistic form and syllogistic matter in the thirteenth century. It led to debates on the ontology of the syllogism as studied in the Prior Analytics, i.e. the syllogism made of letters and the four logical constants a/e/i/o, with deep consequences on the definition of logic as a universal method for all sciences (...) and as a science itself. (shrink)

BackgroundThe present study examined the efficacy of the Michigan Model of Infant Mental Health-Home Visiting infant mental health treatment to promote the socioemotional wellbeing of infants and young children. Science illuminates the role of parental “co-regulation” of infant emotion as a pathway to young children’s capacity for self-regulation. The synchrony of parent–infant interaction begins to shape the infant’s own nascent regulatory capacities. Parents with a history of childhood adversity, such as maltreatment or witnessing family violence, and who struggle with symptoms (...) of post-traumatic stress may have greater challenges in co-regulating their infant, thus increasing the risk of their children exhibiting social and emotional problems such as anxiety, aggression, and depression. Early intervention that targets the infant–parent relationship may help buffer the effect of parental risk on child outcomes.MethodsParticipants were 58 mother–infant/toddler dyads enrolled in a longitudinal randomized control trial testing the efficacy of the relationship-based IMH-HV treatment model. Families were eligible based on child age and endorsement of at least two of four socio-demographic factors commonly endorsed in community mental health settings: elevated depression symptoms, three or more Adverse Childhood Experiences parenting stress, and/or child behavior or development concerns. This study included dyads whose children were born at the time of study enrollment and completed 12-month post-baseline follow-up visits. Parents reported on their own history of ACEs and current posttraumatic stress disorder symptoms, as well as their toddler’s socioemotional development.ResultsMaternal ACEs predicted more toddler emotional problems through their effect on maternal PTSD symptoms. Parents who received IMH-HV treatment reported more positive toddler socioemotional wellbeing at follow-up relative to the control condition. The most positive socioemotional outcomes were for toddlers of mothers with low to moderate PTSD symptoms who received IMH-HV treatment.ConclusionResults indicate the efficacy of IMH-HV services in promoting more optimal child socioemotional wellbeing even when mothers reported mild to moderate PTSD symptoms. Results also highlight the need to assess parental trauma when infants and young children present with socioemotional difficulties. (shrink)

The Ethics of Joy offers reconstructive argument, careful engagement with select literature, and a big-picture presentation of Spinoza’s view of the well-lived human life. Not “convinced that Kantians in ethics are Kantians because of an argument that Kant or Korsgaard makes,” Andrew Youpa urges us to consider Spinoza’s view as “an alternative way of thinking about our lives—an alternative that is illuminating and insightful”. Since “the presentation of an illuminating alternative is arguably the best a philosopher can do”, this is (...) no small task. Youpa argues that Spinozan virtue—human excellence—is defined by our power to care for ourselves and others, not by our accountability. On his reading, power, and... (shrink)

In recent years, Early Modern Philosophy has seen frequent and urgent calls for more diverse, equitable, and inclusive teaching and research. These are calls fo.

Shared decision making has become the standard of care, yet there remains no consensus about how it should be conducted. Most accounts are concerned with threats to patient autonomy, and they address the dangers of a power imbalance by foregrounding the patient as a person whose complex preferences it is the practitioner's task to support. Other corrective models fear that this level of mutuality risks abdicating the practitioner's responsibilities as an expert, and they address that concern by recovering a nuanced (...) but genuinely directive clinical role. Cribb and Entwistle helpfully categorize models of shared decision making as ‘narrower’ and ‘broader’ and praise the latter's ‘open‐ended and fully dialogical ways of relating’. However, they stop short of providing a philosophical account of how that dialogue works. In this paper, a nurse–midwife and a philosopher collaborate to argue that the Socratic model of dialogue offers a solution to the practitioner–patient dilemma. In the Theaetetus, Socrates compares dialogical reasoning to ‘midwifery with all its standard features’. By means of a three‐way analogy, elements of midwifery practice are used to illuminate features of Socrates' claim that his dialogue is like midwifery; those features are then translated into an approach to shared decision making as the ‘midwifery of good thinking’ which both midwives and physicians would do well to adopt. A key concept that emerges is the need for practitioners to make a risk‐confidence assessment of the particular content of any decision to appropriately modulate their role in the practice of shared decision making. (shrink)

Through a rhetorical analysis of fragments of language used by United States public health experts, victims, and advocates during the early periods of polio, HIV and COVID-19, this project shows how constitutive rhetoric within infectious disease discourse articulates the subject position of potential victim for different publics. The author finds that the analyzed discourse simultaneously calls forth a negative identity that asks people to not become something and also asks for actions to prevent disease spread – and, in doing so, (...) the awakening of potential victim reveals hegemonic assumptions about whose bodies are valued and whose are not. (shrink)

At the time of its publication in 2016, Edward K. Chan's The Racial Horizon of Utopia entered a field that included relatively few full-length studies of race in speculative fiction or science fiction, and even fewer of race in utopian literature. Ground-breaking in that respect and offering a compelling examination of race within utopian novels of the 1970s through 1990s, Chan's book makes a vital contribution to the field of utopian studies.Chan notes a shift in focus in post-1970s utopian fiction (...) away from delineating the workings of an imagined utopian society and toward shaping what he refers to as "the Subject of Utopia". In conjunction with this, he identifies this period as characterized by "the... (shrink)

When the Cynic philosopher, Diogenes of Sinope, coins the term ‘cosmopolitan,’ he invites an expansive understanding of the ethical and political commitments one should endeavor to challenge and uphold. Whereas the politics of the day privileged one’s status and role in the polis as foundational for rights, entitlements, duties, and allegiances, the cosmopolitan perspective highlights the arbitrary nature of political boundaries and benefits. This permits virtue, nature, and reason to supplant law and custom as the standards for judgment. After grounding (...) the invention of cosmopolitanism in its political and ethical context, this paper explores what is salient in the notion by attending to it in its own right and as a foil for a different kind of ethically driven political structure, here represented by Plato’s kallipolis. (shrink)

President Trump’s decision to move his official state of residence from high-tax New York to no (income)-tax Florida has brought public attention to an issue that has long troubled scholars, designers and administrators of income tax systems: how the interaction of tax rules deferring the taxation of income and tax rules based on residency allows taxpayers to reduce and even avoid taxation of their deferred income. These discontinuities in tax treatment may lead to excessive migration, as well as reductions in (...) state income tax revenues and distortions in the design of state taxing mechanisms. This Article explains what states would have to do to eliminate these avoidance opportunities. However, it also points out that many of these policy changes would create other tax discontinuities. Ultimately, it leaves open the question whether making any of these changes would lead to fewer financial and behavioral distortions. (shrink)

Is abortion a question of personal morality? Liberals and feminists often embrace this idea, but so also do those who are personally opposed to abortion. Someone may claim to believe personally that abortion is wrong without holding the corresponding public belief. I am interested in what exactly one means when one says that abortion is a question of personal morality. In Sec. II, I consider three influential interpretations of the claim that abortion is a question of personal morality. After showing (...) that each of these interpretations is inadequate, I develop a fourth that avoids some of the problems with the first three (in Sec. III). But even on this interpretation, the claim that abortion is a question of personal morality is difficult to defend. This is because we cannot show that abortion is a question of personal morality without first knowing something about the moral status of the fetus. I conclude the paper with some pessimistic remarks concerning our ability to arrive at a compromise position on abortion. (shrink)

Autobiographical memory is intimately linked to the self. However, the relation between the self and involuntary recall has been understudied. Theoretically, the more relevant an event is to the self the more accessible the memory should be. In line with this prediction, the present study tested the hypothesis that self-relevance of a stressor modulates involuntary recall. Healthy student participants viewed distressing film clips and were presented with information that defined the main characters as more or less similar to them, or (...) without any information about the characters. In line with predictions, participants in the high self-relevance condition reported more involuntary memories of the film clips after one week compared to participants in the low self-relevance and control conditions. The findings support the theoretical relation between the self and memory accessibility and extend findings from previous research to the domain of involuntary recall. (shrink)

This paper explores how knowledge is exchanged between agricultural advisors and farmers in the context of sustainable farming practices in England. Specifically the paper examines the nature of the knowledge exchange at the encounters between one group of advisors, agronomists, and farmers. The promotion of best management practices, which are central to the implementation of sustainable agricultural policies in England, provide the empirical context for this study. The paper uses the notion of expert and facilitative approaches as a conceptual framework (...) for analyzing knowledge exchange encounters between agronomists and farmers. Data were derived from semi-structured interviews with 31 agronomists and 17 farmers, in the context of three initiatives promoting a range of best management practices including (a) targeted use of nitrogen (N), (b) use of nutrients within manure, and (c) management practices to improve soil structure. The interviews revealed that, although many agronomist–farmer knowledge exchange encounters are characterized by an imbalance of power, distrust, and the divergence of knowledge, other encounters provide a platform for the facilitation of farmer learning in their transition to more sustainable practices. (shrink)

Je distingue successivement trois modes d’incertitude en psychanalyse. L’incertitude caractérise d’abord la progressive connaissance d’un cas qui se présente au connaître comme une énigme et qu’il s’agit de construire comme singulier. L’incertitude de la connaissance tient ensuite à l’alliance très particulière du savoir et du non savoir dans la pratique et la théorie de la psychanalyse. Elle tient enfin à la mise au point d’une nouvelle définition du champ même auquel la psychanalyse a affaire : un certain régime des actes (...) dans l’existence humaine qui s’annonce dans le phénomène clinique de la répétition et qui caractérise le pulsionnel comme un « morceau d’activité » à l’œuvre dans la transposition des impasses de la vie pulsionnelle, c’est-à-dire des symptômes par transposition dans le site construit par la cure. (shrink)