This essay explores a theory of panoramas put forward by the experimental postwar German novelist and translator Arno Schmidt. Schmidt claims that panoramas were so pervasive in the visual culture of the nineteenth century that they unconsciously influenced writers of the period, so that when they wanted to describe vast landscapes they unthinkingly framed their descriptions by drawing on experience with specific panoramas. He primarily expounds the theory in his longest work of fiction, Zettel’s Traum (1970), translated as Bottom’s Dream (...) (2016), where he supports it with evidence from Edgar Allan Poe and Jules Verne. He also promoted the theory in later interviews, and regarded it not just as part of his fiction but as a significant discovery in its own right. This essay extracts Schmidt’s theory from its fictional context and illustrates how he thought it could be used hermeneutically to uncover submerged panoramas in the works of nineteenth century authors. We conclude by locating the theory as part of the contemporary reception history of panoramas. (shrink)

AbstractmRNA stability is increasingly recognized as being essential for controlling the expression of a wide variety of transcripts during neuronal development and synaptic plasticity. In this context, the role of AU‐rich elements (ARE) contained within the 3′ untranslated region (UTR) of transcripts has now emerged as key because of their high incidence in a large number of cellular mRNAs. This important regulatory element is known to significantly modulate the longevity of mRNAs by interacting with available stabilizing or destabilizing RNA‐binding proteins (...) (RBP). Thus, in parallel with the emergence of ARE, RBP are also gaining recognition for their pivotal role in regulating expression of a variety of mRNAs. In the nervous system, the member of the Hu family of ARE‐binding proteins known as HuD, has recently been implicated in multiple aspects of neuronal function including the commitment and differentiation of neuronal precursors as well as synaptic remodeling in mature neurons. Through its ability to interact with ARE and stabilize multiple transcripts, HuD has now emerged as an important regulator of mRNA expression in neurons. The present review is designed to provide a comprehensive and updated view of HuD as an RBP in the nervous system. Additionally, we highlight the role of HuD in multiple aspects of a neuron's life from early differentiation to changes in mature neurons during learning paradigms and in response to injury and regeneration. Finally, we describe the current state of knowledge concerning the molecular and cellular events regulating the expression and activity of HuD in neurons. BioEssays 28: 822–833, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

Philosophers of mind and language who advance causal theories face a sort of conjunction problem. When we say that the thing had in mind or the thing referred to is a matter of what causally impacted the thinker or speaker, we must somehow narrow down the long conjunction of items in a causal chain, all of which contributed to the having in mind, but only one of which becomes the object of thought or the linguistic referent. Here, I sketch a (...) notion of cognitive focus intended to do this narrowing. The notion borrows three key aspects from visual focus and some technological aides—causation, amplification, and suppression. I suggest a broader application of this framework to address the conjunction problem not only in ordinary contexts of perceptual focus but also in evidence cases involving non-perceptual cognitive focus. I further suggest cognitive focus is helpful in distinguishing referential vs. attributive thought. (shrink)

Comment et en quoi les études sur le genre permettent de retravailler les disciplines scientifiques? Comment la pré-valence de l'androcentrisme des sciences crée des apories au sein des connaissances scientifiques? En quoi le prisme du genre peut-il requestionner les pratiques scientifiques, particulièrement au sein des sciences dites 'dures' et expérimentales? En quoi le genre permet aussi de renouveler ler l'appréhension des pratiques militantes et professionnelles? et ouvrage s'intéresse aux apports du genre, un concept u des sciences humaines et sociales qui (...) tend à s'appliqu r à la réflexion scientifique menée au sein d'autres mondes de la recherche. Cette inclusion permet de pointer les écueils, dans des domaines scientifiques longtemps restés hermétiques aux enjeux du genre. Il rend compte de travaux récents questionnant les enjeux épistémologiques de la critique féministe des sciences, mais aussi portant sur les questions d'identité de genre ainsi que de santé et de contrôle de la sexualité. II réunit des recherches inédites émanant de diverses disciplines scientifiques : pharmacologie, physiologie, biologie, toxicologie, mais aussi sociologie, anthropologie, histoire, droit et philosophie, présentées par des spécialistes des sciences sociales et des études de genre comme par des Fornnières et pionniers ayant relevé le challenge de croiser s enjeux de genre à des objets de recherche nouveaux. Son originalité tient également à l'apport de réflexions croisées sur les enjeux contemporains du genre émanant des pratiques ancrées sur les terrains militants et professionnels."--Page 4 of cover. (shrink)

A presence for decades in individuals’ everyday life practices and identity formation, the Walt Disney Company has more recently also become an influential element within the "big" curriculum of public and private spaces outside of yet in proximity to formal educational institutions. _Disney, Culture, and Curriculum_ explores the myriad ways that Disney’s curricula and pedagogies manifest in public consciousness, cultural discourses, and the education system. Examining Disney’s historical development and contemporary manifestations, this book critiques and deconstructs its products and perspectives (...) while providing insight into Disney’s operations within popular culture and everyday life in the United States and beyond. The contributors engage with Disney’s curricula and pedagogies in a variety of ways, through critical analysis of Disney films, theme parks, and planned communities, how Disney has been taught and resisted both in and beyond schools, ways in which fans and consumers develop and negotiate their identities with their engagement with Disney, and how race, class, gender, sexuality, and consumerism are constructed through Disney content. Incisive, comprehensive, and highly interdisciplinary, _Disney, Culture, and Curriculum_ extends the discussion of popular culture as curriculum and pedagogy into new avenues by focusing on the affective and ontological aspects of identity development as well as the commodification of social and cultural identities, experiences, and subjectivities. (shrink)

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An important milestone was crossed recently in the discipline of philosophy, but hardly anyone seems to have noticed. In 2004, for the first time since statistics have been gathered on such things, women earned more than 30 percent of the doctorates in philosophy in this country, 33.3 percent, up from 27.1 percent the year before. The highest percentage women had achieved previously in philosophy was 29.4 percent, in..

In Anti‐Oedipus, Deleuze and Guattari aim to describe schizophrenia in a positive manner. According to them, the schizophrenic lives on the intensive order. To fully comprehend what this means, it is key to address some of Deleuze's insights regarding the notion of intensity in relation to experience and cognition. This is why I will combine ideas from Anti‐Oedipus with theory from Difference and Repetition, in order to explain Deleuze and Guattari's conception of intensity in its relation to common sense and (...) to schizophrenia. According to this conception (a), intensity is the condition of possibility and limit for the sensible; (b) it becomes covered over by the organizing principles of common sense, which make our affects more workable and recognizable; and (c) this process of organization must hang together with the codification of desire through Oedipus, the main organizational principle of the socius. On the back of these theoretical considerations, I will explain what it means to say that the schizophrenic lives amongst intensities: (a) this involves a lack of codification of desire and thus of common sense, meaning an absence of organizational principles; and (b) this perspective leads to a different understanding of the schizophrenic's experience and expression, with very concrete implications for a clinical approach to schizophrenia. (shrink)

I take it as given that we manage to linguistically refer to objects we can neither perceive nor uniquely describe. Kripke accounts for this fact by appeal to causal-historical chains of communication. But Evans famously presented what has seemed to many a devastating counterexample to Kripke’s view: the phenomenon of reference-shifting. Here, I’ll agree with critics that Kripke’s view is insufficient to handle cases of reference shift, but I’ll argue for an alternative version of the causal-historical account that is immune (...) to Evans’ counterexample. The key move will be at the foundations; it will require a change in what it is we’re giving a causal-historical account of. Critically, I’ll argue that we should reject two claims associated with the causal-historical picture. First, we should reject the claim that names are used to think of their referents. Second, we should reject the claim that later speakers defer to earlier ones. (shrink)

This experiment uses quantitative and qualitative measures to address the effect of two syllabus statements on academic misconduct: one based on prohibitions and one on academic integrity. Students expressed favorable attitudes toward the statements, showed an increase in guilt compared to a control group, but showed no decrease in intentions to cheat. Including only a standard academic misconduct statement in one's syllabus is not sufficient to alter behavior, which should be acknowledged by faculty.

The rediscovery of Aristotle’s works on syllogisms in the Latin world, especially the Sophistici Elenchi and then the Prior Analytics, gave rise to sophisticated views on the nature of syllogistic form and syllogistic matter in the thirteenth century. It led to debates on the ontology of the syllogism as studied in the Prior Analytics, i.e. the syllogism made of letters and the four logical constants a/e/i/o, with deep consequences on the definition of logic as a universal method for all sciences (...) and as a science itself. (shrink)

Les théories contractualistes de l’âge classique se fondent sur la conception d’un état de nature qui devient, à cause de ses contradictions internes, un état de guerre auquel il faut remédier par un artifice rationnel, le pacte. Alors même que ces contradictions sont issues des passions humaines, celles-ci semblent impensables dans le cadre purement juridique de ces théories, où ne sont analysés ni les mécanismes passionnels d’adhésion au politique, ni la menace de dissolution de l’État. Nous nous attachons à comparer (...) le rôle que Hobbes et Spinoza font jouer aux passions dans l’élaboration de leurs doctrines politiques : tandis que Hobbes témoigne d’un souci constant des passions, tout en les mettant à l’écart lorsqu’il s’agit de penser la construction et le fonctionnement de l’édifice politique, Spinoza permet de penser deux groupes de passions – celles qui résistent nécessairement au corps politique et celles qui lui font obstacle ponctuellement. Ces dernières constituent tout à la fois des facteurs de décomposition et de recomposition du corps collectif. Cette approche du politique à partir des causes de sa dissolution permet d’apporter un éclairage à la signification du droit naturel moderne tel qu’il se construit chez Hobbes et chez Spinoza. (shrink)

IntroductionMilitary personnel and Veterans are at increased risk of mental and physical health conditions, which can impact their families. Spouses often perform a vital role in caring for service members and Veterans facing illness or injury, which can lead to caregiver burden. In turn, this may contribute to relationship issues. Research suggests that ensuring that spouses are well supported can alleviate some of these negative effects. The current study examined whether social support received by spouses of newly released Veterans buffers (...) the impact of Veterans’ health on caregiver burden, subsequently impacting spouses’ relationship satisfaction.MethodsData were collected as part of the Canadian Armed Forces Transition and Well-being Survey. The sample included N = 595 spouses of Regular Force Veterans who released in 2016 with at least 2 years of service. We examined Veterans’ mental and physical health and spouses’ caregiver burden, social support, and relationship satisfaction. A moderated mediation model was tested using structural equation modeling.ResultsThere was a significant indirect association between Veterans’ health and spouses’ relationship satisfaction through caregiver burden. Furthermore, social support moderated the association, as evidenced by a weaker association between Veterans’ health and caregiver burden at low levels of social support compared to high levels.ImplicationsFindings suggest additional efforts should be made to ensure sufficient support is provided to spouses, especially when they are caring for a service member or Veteran facing illness or injury, to strengthen their families’ well-being. (shrink)

Antoine Arnauld is well known as a passionate defender of Jansenism, specifically Jansen’s view on the relation between freedom and grace. Jansen and, early in his career Arnauld, advance compatibilist views of human freedom. The heart of their theories is that salvation depends on both the irresistible grace of God and the free acts of created things. Yet, in Arnauld’s mature writings, his position on freedom seems to undergo a significant shift. And, by 1689, his account of freedom no longer (...) seems Jansenist. In this paper, we offer an interpretation of Arnauld’s mature view on freedom, with a focus on his claim that freedom requires a “power to the opposite.” In order to see what he means by this, we look to several under-examined texts in his corpus for clues about how he understands the related topics of “infallible determination,” habit, and primo-primi motus. We argue that Arnauld’s mature view on freedom should be understood as libertarian. (shrink)

Although I am not supposed to have a favorite patient, she is one. Arissa is a three‐year‐old girl. Her parents, natives of Comoros, had illegally immigrated to the French department of Mayotte. When I first began treating her, I saw her as a time bomb. But we built a relationship, and when she deteriorated on my watch, I wanted to say, “Fight to the end!—she is my favorite patient!” But I thought that I did not have the necessary distance to (...) answer the question. (shrink)

We expand on the article “Ethical Challenges Arising in the COVID-19 Pandemic: An Overview from the Association of Bioethics Program Directors (ABPD) Task Force” to consider the ways in which rural...

_Expanding Curriculum Theory, Second Edition_ carries through the major focus of the original volume—to reflect on the influence of Deleuze and Guattari’s concept of "lines of flight" and its application to curriculum theorizing. What is different is that the lines of flight have since shifted and produced expanded understandings of this concept for curriculum theory and for education in general. This edition reflects the impact of events that have contributed to this shift, in particular the logic of school policy changes (...) and reforms in the past decade, and the continued explosion of social media and its effect on the collective understanding of how both "knowledge" and "education" work as forms of repression. The introduction updates the text and puts it into current debates in the field and in the larger socio-economic milieu. New dis/positions are presented that explore central questions circulating within and outside curriculum studies. Exciting scholarship on a range of topics includes notions of desire and commodities, youth culture and violence, new directions in curriculum theory, Eco-Ethical consciousness, new Deleuzian views of normality, the diffusion of technology and lines of flight in transnational curriculum inquiry. (shrink)

Qu'entendre par modernité? Résulte-t-elle d'une transposition des schèmes théologiques et des dispositifs théologico-politiques propres au christianisme médiéval, ou bien s'est-elle affirmée contre son propre passé théologique, en rupture avec les formes héritées du passé? Et comment situer, dans ce processus, les philosophies de Hobbes et de Spinoza, comprises tantôt comme héritières des théologies de la toute-puissance divine, de l'augustinisme ou de la Réforme, tantôt comme inaugurant le.

This article discusses the discourses of disability through a parallel `disabling' of its own text. It draws on literary as well as sociological sources in order to interrogate the nature and relations of the `tragic', the `heroic' and the `comic'. The authors offer the conclusion that the comic is never quite absent from the discourse of tragedy (after Kundera), and turn that insight back on their own text, in an attempt to refuse the solemnities and closures of their own narrative.

Surprise – these much-publicized rules are not the least bit reassuring to people who specialize in the study of ethics. While attention to ethics is certainly welcome, these ethical codes provide a too-easy cop-out, a way to neatly dispose of attention to nagging and pervasive problems. The typical professional code is little more than a checklist of rules that enables professionals of any stripe to give lip service to ethical behavior without engaging in continuing dialogue on ethical dilemmas. Neatly packaged (...) commandments short-circuit development of the reasoning tools to work through ethical challenges meaningfully and with long-lasting impact on the actual behavior in any field. (shrink)

The U.S. Supreme Court recently held that a parody by the rap group 2 Live Crew of Ray Orbison's song "Oh, Pretty Woman" was "fair use" and thus did not infringe the copyright. Although the court insisted that it was not evaluating the quality of the parody, I argue that it does in fact make several aesthetic evaluations and sometimes even seems to praise the content of the parody. I first consider the stated reasons for the claimed refusal of the (...) court to evaluate aesthetic quality. Second, I examine the evaluations which the court in fact does make, at least some of which are clearly aesthetic evaluations. I then argue that aesthetic value judgments are both necessary and possible for determinations of "fair use" for such works as the "Pretty Woman" parody. (shrink)

The most popular form of reversible contraception in the United States is the female-controlled hormonal birth control pill. Consequently, scholars and lay people have typically assumed that women take primary responsibility for contraceptive decision making in relationships. Although many studies have shown that men exert strong influence in couple’s contraceptive decisions in developing countries, very few studies have considered the gendered dynamic of contraceptive decision making in developed societies. This study uses in-depth interviews with 30 American opposite-sex couples to show (...) that contraceptive responsibility in long-term relationships in the United States often conforms to a gendered division of labor, with women primarily in charge. A substantial minority of men in this study were highly committed contraceptors. However, the social framing of contraception as being primarily in women’s “sphere,” and the technological constraints on their participation, made even these men reluctant to discuss contraception with their women partners. (shrink)

Past research finds that after menopause some women experience negative changes such as vaginal dryness, decreased libido, and decreased orgasm quality; very little research inquires about positive changes. In contrast, this study shifts the research focus from whether women experience menopausal changes to how women view any changes in sex life. Based on 30 in-depth interviews with heterosexual and lesbian women, the author finds that most women emphasize cultural and social issues, such as relationship status and quality, health, and sexual (...) history, rather than menopausal changes when they describe sex after menopause. However, she finds a difference by sexual orientation in how women handle problems in sex. The author concludes by discussing the implication of this research for future menopause and sex research; most important, she emphasizes studying sex in the context of women's lives rather than as a result of the biological changes of menopause. (shrink)

Jeremy Horder, Excusing Crime Oxford: Oxford University Press, 2004, xx + 295 pp.

Synthetic biology can be understood as expanding the abilities and aspirations of genetic engineering. Nonetheless, whereas genetic engineering has been subject to criticism due to its endangering biodiversity, synthetic biology may actually appear to prove advantageous for biodiversity. After all, one might claim, synthesizing novel forms of life increases the numbers of species present in nature and thus ought to be ethically recommended. Two perspectives on how to spell out the conception of intrinsic value of biodiversity are examined in order (...) to assess this line of thought. At the cost of introducing two separate capacities of human knowledge acquisition, the ‘admiration stance’ turns out to reject outright the assumption of a synthetic species' intrinsic value and of an imperative to create novel species. The ‘kinship stance’ by contrast does ascribe value to both synthetic and natural species and organisms. Nonetheless, while from this perspective creating novel species may become an ethical demand under certain conditions, it favours changing organisms by getting in contact with them rather than synthesizing them. It is concluded that neither the admiration nor the kinship stance warrants a supposed general moral obligation to create novel species to increase biodiversity. (shrink)

His is a journey marked by the questioning of experience itself, until what is reached is sovereign laughter, non-knowledge, and a Presence in no way distinct from Absence, where "The mind moves in a strange world where anguish and ecstasy ...

While Specific Informed Consent has been the established standard for obtaining consent for medical research for many years, it does not appear suitable for large-scale biobank and health data research. Thus, alternative forms of consent have been suggested, based on a variety of ethical background assumptions. This article identifies five main ethical perspectives at stake. Even though Tiered Consent, Dynamic Consent and Meta Consent are designed to the demands of the self-determination perspective as well as the perspective of research as (...) a public good, they are still also criticized from both perspectives. In addition, criticisms based on concerns of justice, participation and democratic deliberation, and relational concerns have been levelled at each of the models. As all of these perspectives have valid points to make, the task at hand lies in balancing these ethical perspectives. What constitutes an adequate balancing depends on contextual factors. These factors include digital infrastructure and digital literacy, data safety regulation, good scientific and clinical practice, transparent debates on ethically relevant features of research, social inequalities, anti-discrimination laws and practices, trust in health care institutions and recognition of patient preferences, and consensus on unethical research. We argue that the role of context in determining acceptable models of consent puts the ethical importance of models of consent into perspective. Since altering contextual factors can help to live up to the ethical concerns at stake in debates about models of consent, opting for such a shift of focus comes without ethical loss. (shrink)