Between-subject variability in cognitive performance has been related to inter-individual differences in functional brain networks. Targeting the dorsal attention network we questioned whether resting-state functional connectivity within the DAN can predict individual performance in spatial attention tasks and whether there is short-term adaptation of DAN-FC in response to task engagement. Twenty-seven participants first underwent resting-state fMRI, they subsequently performed different tasks of spatial attention [including visual search ] and immediately afterwards received another rs-fMRI. Intra- and inter-hemispheric FC between core hubs (...) of the DAN, bilateral intraparietal sulcus and frontal eye field, was analyzed and compared between PRE and POST. Furthermore, we investigated rs-fMRI-behavior correlations between the DAN-FC in PRE/POST and task performance parameters. The absolute DAN-FC did not change from PRE to POST. However, different significant rs-fMRI-behavior correlations were revealed for intra-/inter-hemispheric connections in the PRE and POST run. The stronger the FC between left FEF and IPS before task engagement, the better was the learning effect in VS. And the faster the VS, the stronger was the FC between right FEF and IPS after task engagement. To conclude, DAN-FC relates to the individual performance in spatial attention tasks supporting the view of functional brain networks as priors for cognitive ability. Despite a high inter- and intra-individual stability of DAN-FC, the change of FC-behavior correlations after task performance possibly indicates task-related adaptation of the DAN, underlining that behavioral experiences may shape intrinsic brain activity. However, spontaneous state fluctuations of the DAN-FC over time cannot be fully ruled out as an alternative explanation. (shrink)

When is it morally permissible to engage in self-defense or the defense of others? Jonathan Quong gives an original philosophical account of the central moral principles that should regulate the use of defensive force. The morality of defensive force needs to be understood in the context of a more general account of justice and moral rights.

Introduction : ethical economics? -- The sovereign consumer -- Two myths about economic growth -- The politics of pay -- Happiness -- Pricing life and nature -- New worlds of money : public services and beyond -- Conclusion.

This paper explores Emmanuel Levinas' Jewish writings, and in particular, his Talmudic commentaries and essays on Judaism. The aim is to elicit some salient features of his methodological approach to the Jewish sacred texts. In general, Levinas' specific reflections on method (in terms of reading the Jewish Scriptures) are confined to sporadic, fragmentary comments interspersed throughout his writings. In extracting these reflections, a specifically Levinasian approach emerges. In particular, his approach shows how one may ethically encounter the Other(s) in these (...) sacred texts. (shrink)

In this 2001 book Jonathan Price attempts to demonstrate that Thucydides consciously viewed and presented the Peloponnesian War in terms of a condition of civil strife - stasis, in Greek. Thucydides defines stasis as a set of symptoms indicating an internal disturbance in both individuals and states. This diagnostic method, in contrast to all other approaches in antiquity, allows an observer to identify stasis even when the combatants do not or cannot openly acknowledge the nature of their conflict. The (...) words and actions which Thucydides chooses for his narrative meet his criteria for stasis: the speeches in the History represent the breakdown of language and communication characteristic of internal conflict, and the zeal for victory led to acts of unusual brutality and cruelty, and overall disregard for genuinely Hellenic customs, codes of morality and civic loyalty. Viewing the Peloponnesian War as a destructive internal war had profound consequences for Thucydides' historical vision. (shrink)

This volume collects all of Firth’s major published writings, two sets of unpublished lectures, and three essays from his unfinished book on epistemology. John Troyer provides a very helpful overview of the essays, as well as a short biography of a person of deep convictions and a devoted teacher and colleague. : 109-18, should also be consulted.).

My critical comments focus mainly on premises,, and. However, in treating these I will address other of James’s assumptions—particularly, the presupposition of his argument that it is possible to will to believe. Later I will try to accommodate existential aspects of James’s argument that retain value, even if my objections to his argument stand.

This book provides the first systematic, book-length defence of natural law ideas in ethics, politics and jurisprudence since John Finnis's influential Natural Law and Natural Rights. Incorporating insights from recent work in ethical, legal and social theory, it presents a robust and original account of the natural law tradition, challenging common perceptions of natural law as a set of timeless standards imposed on humans from above. Natural law, Jonathan Crowe argues, is objective and normative, but nonetheless historically extended, socially (...) embodied and dependent on contingent facts about human nature. It reflects the ongoing human quest to work out how best to live flourishing lives, given the natures we have and the social environments we inhabit. The nature and purpose of law can only be adequately understood within this wider context of value. Timely, wide-ranging and clearly written, this volume will appeal to those working in law, philosophy and religious studies. (shrink)

An epistemic account of fallacies is one which takes it as a necessary condition for a fallacy that it has a tendency to produce false or unwarranted beliefs. The most sophisticated form of this account occurs in an article by Robert J. Fogelin and Timothy J. Duggan (“Fallacies,”Argumentation 1, 1987, pp. 255–262). I criticize the Fogelin and Duggan proposal, in particular, and epistemic accounts, more generally. Though an epistemic approach is attractive, it enlarges the class of fallacies, beyond what would (...) be permitted by traditional accounts. I also question thenecessity of fallacies leading to unwarranted beliefs. Some fallacies are fallacious due to their expected harm to argument practices. This position touches on a theme in the work of Van Eemeren and Grootendorst, though I criticize their notion of rules of argument as too broad. (shrink)

In this book, nine thought-leaders engage with some of the hottest moral issues in science and ethics. Based on talks originally given at the annual "Purdue Lectures in Ethics, Policy, and Science," the chapters explore interconnections between the three areas in an engaging and accessible way. Addressing a mixed public audience, the authors go beyond dry theory to explore some of the difficult moral questions that face scientists and policy-makers every day. The introduction presents a theoretical framework for the book, (...) defining the term "bioethics" as extending well beyond human well-being to wider relations between humans, nonhuman animals, the environment, and biotechnologies. Three sections then explore the complex relationship between moral value, scientific knowledge, and policy making. The first section starts with thoughts on nonhuman animal pain and moves to a discussion of animal understanding. The second section explores climate change and the impact of "green" nanotechnology on environmental concerns. The final section begins with dialog about ethical issues in nanotechnology, moves to an exploration of bio-banks (a technology with broad potential medical and environmental impact), and ends with a survey of the impact of biotechnologies on (synthetic) life itself. (shrink)

A much disputed conceptual argument aims to show the impossibility of direct believing at will. Regardless of the success of this argument, it has been held to be impotent against indirect forms of belief-control, such as by developing oneself to be more careful or fair-minded in evaluating evidence. However, the shift to indirect forms inherits difficulties connected to the conceptual argument.

The present argument assumes that teaching through modeling attempts to teach the intellectual virtues not primarily as an independent goal of education as, for example, a way to build good character, but for its value to inquiry. I argue that intellectual vices (such as being gullible, dogmatic, pigheaded, or prejudiced)—while harmful to inquiry in certain ways—are essential to its well functioning. Furthermore, to the extent that teaching models critical inquiry, there are educational lessons for which some students ought to take (...) a dogmatic or narrow minded commitment to certain hypotheses or positions; and then, insofar as this modeling works, it will promote these intellectual vices. In Part I of what follows, I develop my argument; in Part II, I respond to the objection that diversity of ideas and attitudes need not—and ought not—call upon the promotion of intellectual vices. (shrink)

This paper explores the implications of the epistemic distinction between the grounds that are relevant for justification in normal knowledge-claim contexts and those that are relevant in philosophical knowledge-claim contexts for inductive logics.

Whereas conventional analyses characterize environmental problems as examples of market failure, proponents of free-market environmentalism (FME) consider the problem to be a lack of markets and, in particular, a lack of enforceable and exchangeable property rights. Enforcing property rights alleviates disputes about, as well as the overuse of, most natural resources. FME diagnoses of pollution are much weaker, however. Most FME proponents suggest that common-law tort suits can adequately protect private property and ecological resources from pollution. Yet such claims have (...) not been substantiated. Further research is needed before the common law, or regulatory reforms grounded in common-law principles, can be seen as a viable alternative to traditional environmental regulation. (shrink)

James’ The Will to Believe is the most influential writing in the ethics of belief. In it, James defends the right and rationality to believe on non-evidential grounds. James’ argument is directed against Clifford’s “Evidentialism” presented in The Ethics of Belief in which Clifford concludes that “[i]t is wrong always, everywhere, and for anyone, to believe anything upon insufficient evidence”. After an overview of the James-Clifford exchange and James’ argument, I reconstruct his argument in detail. Subsequently, I examine four steps (...) in James’ argument, and try to show that these amount to fallacies – enticing to reason, but not cogent. (shrink)

The first part of this paper contextualizes the debate on the ethical regulation of Artificial Intelligence, and then reviews the main Anglo-Eurocentric elements of public initiatives about the ‘Ethics of AI’ that have recently emerged. All this with the ultimate purpose of analyzing the basis of principlism of the Ethics of AI. We refer to this with the specific purpose of presenting it in terms of a paradigmatic case of ‘colonized’ ethics that hides the different moral judgments and the alternative (...) cultural axiologies. We begin with the hypothesis that there is a possibility of questioning the real purpose and contribution of this applied ethics, using a dilemmatic perspective specific to human and legal sciences. In order to execute this type of analysis, which is highly required to understand what the future of these proposals is and how it can affect the regulation of AI, an analysis related to the contemporary literature from the Decoloniality field will be performed. (shrink)

The extreme length of chromosomal DNA requires organizing mechanisms to both promote functional genetic interactions and ensure faithful chromosome segregation when cells divide. Microscopy and genome‐wide contact frequency analyses indicate that intra‐chromosomal looping of DNA is a primary pathway of chromosomal organization during all stages of the cell cycle. DNA loop extrusion has emerged as a unifying model for how chromosome loops are formed in cis in different genomic contexts and cell cycle stages. The highly conserved family of SMC complexes (...) have been found to be required for DNA cis‐looping and have been suggested to be the enzymatic core of loop extruding machines. Here, the current body of evidence available for the in vivo and in vitro action of SMC complexes is discussed and compared to the predictions made by the loop extrusion model. How SMC complexes may differentially act on chromatin to generate DNA loops and how they could work to generate the dynamic and functionally appropriate organization of DNA in cells is explored. -/- . (shrink)

A case is made for focusing less on acts than on facts about behaviour. This fits with the use of fact‐causation, which is conceptually superior to event causation; it fits with the ‘by’‐locution, on the only viable analysis of that given so far, and it avoids needless difficulties that arise when one tries to make the act concept do work for which it is not fitted.

The making/allowing distinction tends to be accompanied by three other considerations that do have moral significance: ease of avoidance, motive, and knowability of consequences. Much discussion of making/allowing is based on intuitions about contrasted pairs of cases—a procedure that has dangers against which this chapter warns. Any thesis to the effect that making/allowing sometimes makes a moral difference is a sign of uncompleted work; the result is not interesting until we know the differentia.

_An ambitious new history of philosophy in English that broadens the canon to include many lesser-known figures__ “[This] lively chronicle of philosophy in English is a splendid accomplishment sufficient unto itself. Highly intelligent, always even-handed, quietly but consistently witty, _Witcraft _is an excellent guide along the twisted and tricky path of human thought.”—___Wall Street Journal__ Ludwig Wittgenstein once wrote that “philosophy should be written like poetry.” But philosophy has often been presented more prosaically as a long trudge through canonical authors (...) and great works. But what, Jonathan Rée asks, if we instead saw the history of philosophy as a haphazard series of unmapped forest paths, a mass of individual stories showing endurance, inventiveness, bewilderment, anxiety, impatience, and good humor? Here, Jonathan Rée brilliantly retells this history, covering such figures as Descartes, Locke, Kant, Hegel, Marx, Nietzsche, Mill, James, Frege, Wittgenstein, and Sartre. But he also includes authors not usually associated with philosophy, such as William Hazlitt, George Eliot, Darwin, and W. H. Auden. Above all, he uncovers dozens of unremembered figures—puritans, revolutionaries, pantheists, feminists, nihilists, socialists, and scientists—who were passionate and active readers of philosophy, and often authors themselves. Breaking away from high-altitude narratives, he shows how philosophy finds its way into ordinary lives, enriching and transforming them in unexpected ways. (shrink)

The English Civil War brought an end to government censorship of nonconformist texts. The resulting exegetical and hermeneutical battles waged over baptism among paedobaptists and Baptists continued well into the Restoration period. A survey of the post-Restoration polemical literature reveals the following themes: 1) the polemical ‘slippery slope’ is a major feature of these tracts. Dissenting paedobaptists believed that Baptists would inevitably become Quakers, despising baptism altogether, and that the resulting social instability would allow the tyranny of Roman Catholicism to (...) reemerge in England. Baptists for their part compared the tyranny of paedobaptist argumentation to the tyranny exercised by Roman Catholics. Anti- Quakeriana and Anti-Popery were both central ‘devil terms’ in this polemical warfare; 2) the exegesis of biblical texts underlying infant baptism revealed contrary understandings of how the bible fit together as a whole. Baptists tended to read Old and New Testaments disjunctively, whereas paedobaptists saw continuity absent explicit abrogation; 3) scholastic theology continued to undergird the arguments of all parties. Especially relevant to this discussion was debate over the proper ‘matter’ and ‘form’ of baptism. Here exegetical and hermeneutical disputes were also relevant. This study reveals that patterns of reading Scripture in each community were informed by traditions and practices, and that the search for the objective ‘literal’ sense of the text was bound to be unavailing. (shrink)

Elqayam & Evans (E&E) argue that we should avoid evaluative normativity in our psychological theorizing. But there are two crucial issues lacking clarity in their presentation of evaluative normativity. One of them can be resolved through disambiguation, but the other points to a deeper problem: Evaluative normativity is too tightly-woven in our theorizing to be easily disentangled and discarded.