Autism is a group of complex neurodevelopmental disorders characterized by impaired social interaction and restricted/repetitive behavior. We performed a large-scale retrospective analysis of 1,996 clinical neurological structural magnetic resonance imaging (MRI) examinations of 781 autistic and 988 control subjects (aged 0 to 32 years), and extracted regionally distributed cortical thickness measurements, including average measurements as well as standard deviations which supports the assessment of intra-regional cortical thickness variability. The youngest autistic participants (< 2.5 years) were diagnosed after imaging and were (...) identified retrospectively. The largest effect sizes and the most common findings not previously published in the scientific literature involve abnormal intra-regional variability in cortical thickness affecting many (but not all) regions of the autistic brain, suggesting irregular gray matter development in autism that can be detected with MRI. Atypical developmental patterns have been detected as early as 0 years old in individuals who would later be diagnosed with autism. (shrink)

The phenomenon of disagreement has recently been brought into focus by the debate between contextualists and relativist invariantists about epistemic expressions such as ‘might’, ‘probably’, indicative conditionals, and the deontic ‘ought’. Against the orthodox contextualist view, it has been argued that an invariantist account can better explain apparent disagreements across contexts by appeal to the incompatibility of the propositions expressed in those contexts. This paper introduces an important and underappreciated phenomenon associated with epistemic expressions — a phenomenon that we call (...) reversibility. We argue that the invariantist account of disagreement is incompatible with reversibility, and we go on to show that reversible sentences cast doubt on the putative data about disagreement, even without assuming invariantism. Our argument therefore undermines much of the motivation for invariantism, and provides a new source for constraints on the proper explanation of purported data about disagreement. (shrink)

Objective interpretations of probability are usually discussed in two varieties: frequency and propensity accounts. But there is a third, neglected possibility, namely, probabilities as deriving from ranges in suitably structured initial state spaces. Roughly, the probability of an event is the proportion of initial states that lead to this event in the space of all possible initial states, provided that this proportion is approximately the same in any not too small interval of the initial state space. This idea can also (...) be expressed by saying that in the types of situations that give rise to probabilistic phenomena we may expect to find an initial state space such that any "reasonable" density function over this space leads to the same probabilities for the possible outcomes. This "method of arbitrary functions" was introduced by Poincaré, studied and extended by Hopf and more recently by Eduardo Engel, Jan von Plato and Michael Strevens. The natural-range, or method-of-arbitrary-functions approach to probabilities is usually treated as an explanation for the occurrence of probabilistic patterns, whereas I examine its prospects for an objective interpretation of probability, in the sense of providing truth conditions for probability statements that do not depend on our state of mind or information. The main objection to such a proposal is that it is circular, i.e. presupposes the concept of probability, because a measure on the initial state has to be introduced, and density functions over the space are considered. I try to argue that this objection can be successfully met. (shrink)

Ego sum moribundus, or Heidegger's call -- I am the dead person I see in the mirror, or Lacan's subject -- Return to Descartes -- the equivocations of phenomenology -- The field of immanence -- The carnal synthesis, the chiasm -- How touching touches itself touching : the (im)possibility of the chiasm -- In contact with the untouchable : the remainder -- This is (not) my body : the remainder of incorporation -- Beyond the other -- The crisis of the (...) chiasm -- From hatred to love -- From archi-agony to resurrection -- Toward deliverance (instasy). (shrink)

Business ethics, corporate social responsibility, corporate citizenship, values-driven management, corporate governance, and ethical leadership are necessary ...

Recent proposals for human-centered AI (HCAI) help avoid the challenging task of specifying an objective for AI systems, since HCAI is designed to learn the objectives of the humans it is trying to assist. We think the move to HCAI is an important innovation but are concerned with how an instrumental, economic model of human rational agency has dominated research into HCAI. This paper brings the philosophical debate about human rational agency into the HCAI context, showing how more substantive ways (...) to understand human objectives may improve HCAI. We contrast the economic approach with two more substantive modern alternatives: the realist and constructivist approaches to human rational agency. The realist approach holds that rational agents pursue what is good, while the constructivist approach holds that rational agents make autonomous choices. We illustrate each by considering its implications for fine-tuning large language models for chatbots such as ChatGPT. (shrink)

Objective: Deep brain stimulation targeted to the ventral intermediate nucleus of the thalamus is effective for motor symptoms in essential tremor, but there is limited data on cognitive outcomes. We examined cognitive outcomes in a large cohort of ET DBS patients.Methods: In a retrospective analysis, we used repeated-measures ANOVA testing to examine whether the age of tremor onset, age at DBS surgery, hemisphere side implanted with lead, unilateral vs. bilateral implantations, and presence of surgical complications influenced the cognitive outcomes. Neuropsychological (...) outcomes of interest were verbal memory, executive functioning, working memory, language functioning, visuospatial functioning, and general cognitive function.Results: We identified 50 ET DBS patients; 29 males; the mean age of tremor onset was 35.84 years with a median age of 38 years. The mean age at DBS was 68.18 years. There were 37 unilateral 30 left, seven right, and 13 bilateral brain implantations. In the subgroup analysis, there was a significant interaction between assessment and age of tremor onset ; F = 4.47; p = 0.043 for working memory. The post hoc testing found improvements for younger onset ET. Similarly, there was a significant interaction between assessment and complications vs. no complications subgroups; F = 4.34; p = 0.043 for verbal memory with worsening scores seen for ET patients with complications. The remaining tests were not significant.Conclusion: In this large cohort of ET patients with, DBS was not accompanied by a significant decline in many cognitive domains. These outcomes were possibly related to the selection of patients with normal cognitive functioning before surgery, unilateral DBS implantations for the majority, and selection of patients with optimal response to DBS. (shrink)

Two basic theses underlie this work. The first, the specificity theorem, signifies that logic is essentially concerned with specific events and not with universal and transcendent systems. The second, the interbehavioral theorem, implies that no matter how logic is defined, it entails a psychological dimension that must be taken into account.

Traditional scholarly attention to human tragedy has been confined mainly within the artificial world of drama and literature. It has neglected to recognize the significant recurrence of tragedy throughout the entire realm of nature. This book attempts to place tragedy within the larger context of natural events, and to view it against a background of scientific philosophy and psychology.

Kant's political philosophy draws a distinction between 'passive' citizens who are merely protected by the law and 'active' citizens who may also contribute to it. Although the distinction between passive and active citizens is often dismissed by scholars as an 'illiberal and undemocratic' relic of eighteenth century prejudice, the distinction is found in every democracy that distinguishes between mere inhabitants -- such as tourists and guestworkers -- and enfranchised citizens. The purpose of this essay is both interpretive and suggestive. First, (...) I will argue that Kant's mature distinction between active and passive citizens follows from an institutional deficiency in the the developing state rather than the natural deficiency of passive citizens, as Kant's critics have alleged. Second, I will draw on systematic features of Kant's political thought in order to claim that the state has a duty to create the institutional conditions of universal active citizenship. (shrink)

"In this book, the second edition of the author's Principles of Psychology, he continues his attempt to forge naturalistic constructs (descriptions, interpretations) for psychological events. Despite the enormous development of psychology in the interval, the author still stresses the fact that psychological events are in all respects as natural as chemical reactions, electromagnetic radiation, or gravitational attraction. The attempt to transform psychology into a natural science is doubly motivated. First, there is the need to develop valid constructs for an important (...) series of happenings. Second, such results smooth the way for workers in other sciences such as physics, physiology, and anthropology in their inevitable encounter with psychological issues"--Preface. (PsycINFO Database Record (c) 2010 APA, all rights reserved). (shrink)

If Kant’s theory of justice is known for one thing, it is for offering a vision of a perfectly just society that is utterly disconnected from the imperfect societies that we occupy. The purity of Kant’s account has attracted criticism from those who claim that if a theory of justice is to be practical, it must offer more than a vision of a perfectly just society. It must also explain how existing societies mired in injustice are to be brought into (...) ever-closer conformity with the ideal that justice prescribes. In this essay, I will argue that this is exactly what Kant’s mature legal and political theory offers. To discern this feature of Kant’s theory, a neglected component must be integrated into his broader framework. This component is what Kant refers to in Toward Perpetual Peace as a permissive law of public right. (shrink)

One hundred and ninety‐six Israeli middle‐school students participated in a study that explored the effects of moral orientation (moral versus conventional)and of three situational variables on attitudes toward two types of cheating in school exams—copying from others (‘active’)and letting others copy (‘passive’). Several vignettes that were comprised of different combinations of the three situational variables—exam importance, supervision level and peers' norms—were used as the main instrument. It was found that a‐morally oriented students approved significantly more of cheating than morally oriented (...) students. Importance of exam had marginally significant effects on active copying. Level of supervision during exam and classmates' norms had significant effects on both active and passive cheating attitudes. (shrink)

The ‘expropriation of the expropriators’ is a delicious turn of phrase, one that Marx even compares to Hegel’s infamous ‘negation of the negation’. But what does it mean, and is it still relevant today? Before I analyse the content of Marx’s expression, I briefly consider contemporary legal understandings of expropriation, as well as some examples of it. In the remainder of the essay, I spell out different kinds of expropriation in Marx and focus on an ambiguity at the core of (...) the notion of ‘expropriating the expropriators’, namely, whether it describes an immanent and objective tendency within the development of the capitalist mode of production or else actively prescribes a form of revolutionary political praxis for the working class. My answer is that it does both, though not without tension. Finally, I develop some implications of these reflections by showing how the concept of expropriation can be put to use today, in struggles around housing, climate and work. (shrink)

The title of this dissertation is a question: Is there a future to Marxist humanism? The work itself is an affirmative answer. The motive behind asking this question is the perennial debate surrounding the relevance of Marxism as a school of social and political thought. There are aspects of Marxism that are, arguably, no longer tenable, yet there are others that are more relevant today than ever. It is the argument of the following dissertation that Marxist humanism is of continued (...) relevance as both an analytical tool as well as a fertile ground for a political project of emancipation. However, the notion of a uniquely "Marxist humanism" is problematic. The fact that it is "Marxist" might lead to the confusion that it is thus based solely on the teachings of Karl Marx. Although his works provide the groundwork to the present project, it is the spirit and not necessarily the letter of Marxism that motivates the following discussion. That is, Marx's humanist project can continue without necessarily relying on his more questionable doctrines. The spirit of Marxist humanism lies in its demand for human well-being through mutual recognition achieved within an appropriately amenable social space wherein economic relations form the foundation to other equally as important intersubjective relationships. Marxist humanism is concerned primarily with the promotion of human values, namely, the alleviation of suffering and the promotion of human flourishing through a systemic change in the structure of society, beginning with economics but encompassing all areas of interpersonality... (shrink)

Introduction 1 P. D. Magnus and Jacob Busch 1. Form-driven vs. Content-driven Arguments for Realism 8 Juha Saatsi 2. Optimism about the Pessimistic Induction 29 Sherrilyn Roush 3. Metaphysics between the Sciences and Philosophies of Science 59 Anjan Chakravartty 4. Nominalism and Inductive Generalizations 78 Jessica Pfeifer 5. Models and Scientific Representations 94 Otávio Bueno 6. The Identical Rivals Response to Underdetermination 112 Gregory Frost-Arnold and P. D. Magnus 7. Scientific Representation and the Semiotics of Pictures 131 Laura Perini (...) 8. Philosophy of the Environmental Sciences 155 Jay Odenbaugh 9. Value Judgements and the Estimation of Uncertainty in Climate Modeling 172 Justin Biddle and Eric Winsberg 10. Feminist Standpoint Empiricism: Rethinking the Terrain in Feminist Philosophy of Science 198 Kristen Intemann 11. Naturalism and the Enlightenment Ideal: Rethinking a Central Debate in the Philosophy of Social Science 226 Daniel Steel 12. New Approaches to the Division of Cognitive Labor 250 Michael Weisberg. (shrink)

I discuss a proposal by Jim Higginbotham for distinguishing mastery of a concept and knowing a conception.

In legal orders around the world, commitments to democracy, liberalism and constitutionalism are increasingly eroding. Although political and constitutional theorists often lament this trend, they invariably adopt frameworks that are indifferent to these commitments. My aims in this article are both critical and constructive. As a critical matter, I will expose the indifference of the leading political and constitutional theories to the emergence, maintenance and refinement of liberal democratic constitutional orders. As a constructive matter, I will draw on Immanuel Kant’s (...) constitutional theory to explain why realizing such a form of governance is a public duty and why receding from it is a public wrong. (shrink)

James Bond 007 strode into the human imagination in the novel Casino Royale in 1953 and hit the movie screens with Dr. No in 1962. He has become one of the best-known personalities, real or imagined, in global history. One out of every four people in the entire world has now seen a Bond movie, and every month thousands of new readers become addicted to Ian Fleming’s original Bond stories. In James Bond and Philosophy, seventeen scholars examine hidden philosophical issues (...) in the hazardous, deceptive, glamorous world of Double-0 Seven. Is Bond a Nietzschean hero who graduates "beyond good and evil"? Does Bond paradoxically break the law in order, ultimately, to uphold it like any "stupid policeman"? What can Bond’s razor-sharp reasoning powers tell us about the scientific pursuit of truth? Does 007’s license to kill help us understand the ethics of counterterrorism? What motivates all those despicable Bond villains—could it be a Hegelian quest for recognition? (shrink)

Religion scheint auf den ersten Blick eine besondere Anfälligkeit für Dogmatismus zu besitzen. Religiöse Überzeugungen sind häufig tief im Leben der Menschen verankert und religiöse Hingabe scheint in Spannung zu jedem Zweifel an dem Inhalt der jeweiligen Religion zu stehen. Auf der Basis von Ernst Cassirers Überlegungen kann im Gegensatz zu diesem Anschein eine Konzeption von Religion entwickelt werden, wonach sich diese gerade durch eine kritische Reflexion auf die eigenen Inhalte auszeichnet und im Gegensatz zu Aberglauben, Irrglaube und Wahnglaube, zu (...) immer größerer Entfaltung von Freiheit führt. (shrink)

Like Aristophanes’ Frogs, Plato’s Symposium stages a contest between literary genres. The quarrel between Socrates and Aristophanes constitutes the primary axis of this contest, and the speech of Alcibiades echoes and extends that of Aristophanes. Alcibiades’ comparison of Socrates with a satyr, however, contains the key to understanding Socrates’ implication, at the very end of the dialogue, that philosophy alone understands the inner connectedness, and hence the proper nature, of both tragedy and comedy. I argue that Plato reflects in the (...) character of Socrates the primordial wisdom embodied in satyric drama. I conclude with a brief consideration of Nietzsche’s challenge to Plato’s Dionysian wisdom. (shrink)

Jerry Fodor argued for an account of belief attribution very close to the theory of direct reference. I argue that his account conflicts with constraints on psychological explanation which he ought to accept.

This dissertation studies how Aristotle understands and justifies his Rhetorical Art. It proceeds by explicating the Art in its intellectual context. Rhetoric emerges as a dynamic investigation of human affairs working through the "given" in speech and thought to a plausible account, while giving consideration to the opinions and characters of both speaker and audience within the horizon of a particular occasion. The basic dynamic determines a structure which is comparable to Socrates' requirements in the Phaedrus. That this is the (...) structure and dynamic is supported by considering the fundamentally contingent nature of human experience, understanding the inference types , common sense principles and starting points by which such experience is explicated, and placing such experience in three mutually exclusive genres. Aristotle's art is essentially the resulting plausible account while actual composition is supplementary. ;Aristotle limits the art by reference to dialectic and ethical life. When it is seen that Aristotle's Organon is not a science of logic and the Posterior Analytics is a rarely applicable mode of presentation, the point of dialectic becomes accessible. It too involves strenuous grappling with speech and thought, but its highest purpose lies in peirastic. Peirastic and sophistry are uses of dialectic which have a contrasting moral color. Peirastic aims at the discovery of ignorance and, at the same time, the difference between accident and essence and knowledge and opinion: Being educated is essentially knowing what one does not know. ;What Socrates only alludes to as political art, Aristotle attempts to expound as praxis perfected into phronesis. Even Aristotle does no more than suggest the nature of phronesis negatively as simultaneously a seeking, a finding and an act which is both self-determination and self-knowledge, and none of these separately; it is profoundly disruptive of existing opinion and most clearly to be seen in the rejection of the laws and rules upon which, as deliberation, it is dependent. The Art differs from Gorgias' rhetoric in its emphasis on the plausible and in its subordination to an ethical self-determination that gains the weight of experience appropriated by intelligence and virtue. (shrink)

The complexities of Henry More's eclectic Neoplatonism and his recklessly energetic poetic style have hitherto deterred scholars from undertaking a complete study of his long philosophical poem, A Platonick Song of the Soul . The aim of my dissertation is to study the Platonick Song in its entirety. I attempt to unravel the different strands of thought that it is woven of and reveal the consistency of thought and architectonic scheme of the work. ;The major themes of the Platonick Song (...) are the immateriality of the soul, its immortality, and its unfailing consciousness. I begin my study with an appraisal of More's work as an answer to Lucretius's De Rerum Natura, which had proclaimed the corporeality and mortality of the soul. The first poem of the Platonick Soul, "Psychozoia" is studied as an allegorical prelude to the work, and the Plotinian and Chaldean origins of More's systems are examined. The five poems after "Psychozoia" are divided into three sections dealing with the immortality of the soul , the macrocosmic manifestation of the soul and the alert soul "Antipsychophannychia," "The Praeexistency of the Soul" and "Antimonopsychia"). In the course of these three chapters, I have occasion to demonstrate More's reliance on the arguments of Ficino and Galileo. In the final chapter of my study, I reveal the importance of the Platonick Song for an understanding of the metaphysics, psychology and ethics of More's mature philosophy. In addition, I analyze the ways in which More's concepts of spirit, matter, space and the Deity resembled and differed from those of his Cambridge friend, Isaac Newton. (shrink)

I examine two views of Professor Von Wright's: in the philosophy of action and in the philosophy of perception. I partly agree and partly disagree with him.

In his ‘On a Supposed Right to Lie from Philanthropy’ Kant makes the astonishing claim that one is not entitled to lie even to save a friend from a murderer. This claim has been an embarrassment for Kant's defenders and an indication of Kant's excessive rigour for his detractors. Responses to SRL fall into three main groups. The first of these groups, that of Kant's critics, claim that SRL demonstrates that Kant's ethical views are so rigorous that they become abhorrent (...) in practice. The second group, Kant's defenders, argues that Kant's conclusions in SRL do not follow from his own ethical principles. The third group, made up of scholars who are generally sympathetic to Kant's position, attempts to explain why a liar is responsible for all the bad consequences that follow from his act by providing an account of Kant's theory of imputation. (shrink)

Can we describe certain sonic experiences as “homely,” even when they take place outside of a traditional home-space? While phenomenological accounts of home abound, with writers detailing a rich spectrum of the felt characteristics of the homely including safety, familiarity, and affective “warmth,” there is a scarcity of research into sonic experience that engages with such literatures. With specific interest in the experience of embodied space, I account here for what might be termed feelings of “sonic homeliness” as they emerge (...) during headphone listening. After forming a conceptual model of homeliness that draws from phenomenological philosophy, I investigate its applicability to experiences of headphone listening. Through analysis of primary interview data, I consider how headphones may be said to territorialize space for listeners, analyzing how sonic “boundaries” are experienced in relation to the body, as well as how some listeners describe their experiences as interiorized, comforting, and “wombic.”. (shrink)

After offering a definition of “conspiracy theory” and highlighting some interesting interconnections between conspiracy theories and religious worldviews, we turn to epistemologically relevant analogies. Proponents of conspiracy theories and religions have often been accused of the same biases and epistemic vices, e.g., gullibility, hypersensitive proneness to personal explanations, or overemphasis on holistic thinking. So-called Generalism is best understood as the thesis that conspiracy theories are guilty until proven innocent because they share certain “bunkum-making properties.” However, we argue for the particularist (...) position, i.e. the position that a general epistemic presumption against conspiracy theories is not tenable. Building a negative valence into the very notion of conspiracy theory is not convincing either. Given the analogies, our analysis supports similar verdicts with respect to religious worldviews: Like conspiracy theories, they should be evaluated on a case-by-case basis rather than being dismissed simply for being religious. Finally, we reject Bezazel’s view that both conspiracy theories and religious worldviews constitute a-rational frames or “bliks” that, besides other things, ground what counts as an explanation. Such a proposal squares badly with epistemic misgivings about particularly preposterous examples of conspiracy theories and religious worldviews. (shrink)