Advance directives are written documents that give patients the opportunity to communicate their preferences regarding treatments they do or do not want to receive in case they become unable to make decisions. Commonly used pre-printed forms have different formats. Some offer space for patients to appoint a surrogate decision maker, and/or to determine future medical treatments and/or give a statement of personal values. So far it is unknown which forms GPs preferably use and why they decide to do so. 23 (...) semi-structured interviews with GPs were analysed using content analysis. Interviewees mainly use short templates and medium length templates with checkboxes to indicate patients’ preferences in regards to life prolonging measures. Especially when patients faced the progression of a disease, participants use the latter version. Only then, the interviewees remarked, patients are capable to rate concrete situations reliably. GPs also realize the importance of the verbal assessment of patients’ preferences; however they rarely keep a written form of the conversation. Some GPs hand out one or more templates and ask their patients to read and think about them at home with the option to talk to them about it later on, while others prefer their patients to fill them out alone at home. Regardless of template usage, most GPs emphasize that ADs require regular updates. GPs tend to see standardized advance directives mainly as a tool to start a conversation with their patients and to identify their real preferences and values. When the patient is still not facing the progression of an already existing disease it could be sufficient to only appoint a surrogate decision maker instead of creating a full AD. However, in all other situations, appointing a surrogate decision maker should be backed up by a written statement of a patient’s general values. Patients and their relatives should always have the opportunity to ask their GP for medical advice when drafting an AD. It is crucial to regularly verify and update existing ADs within the course of a disease. (shrink)

Unintended negative outcomes on child behavior due to lockdown and home confinement following the corona virus disease pandemic needs highlighting to effectively address these issues in the current and future health crises. In this sub-study of the ODIN-study, the objectives were to determine whether the Danish lockdown and home confinement following the COVID-19 pandemic affected changes in emotional-behavioral functioning of pre-school-aged children using the validated Strength and Difficulties Questionnaire answered by parents shortly before lockdown and 3 weeks into lockdown, and (...) moreover, to examine whether baseline family and social characteristics could predict change in child emotional-behavioral functioning during lockdown. Parents of 40 children with a mean age of 5.0 completed the baseline questionnaire and the lockdown follow-up questionnaire. The SDQ-Total difficulties score and Prosocial Behavioral score changed significantly from pre- to lockdown [SDQ-TD mean: 6.0 and 7.9; P = 0.02, respectively and PSB mean: 8.5 and 7.9; P = 0.03, respectively]. Attending leisure time activities before lockdown was a predicting factor of changes to the worse in the children’s SDQ-TD scores, with a mean difference in SDQ-TD between those with and without activities of 3.16 ; P = 0.03. In conclusion, the study showed a modest decrease in child-emotional behavioral functioning during the COVID-19 lockdown, potentially due to parental stress. Although these results might not be generalizable due to small sample size and selected population, the results point to a need of a greater awareness of child mental wellbeing during a lockdown situation. (shrink)

Verse treatises on Advaita Jaina, and Nyaya philosophy.

Absolute and relative outcome measures measure a treatment’s effect size, purporting to inform treatment choices. I argue that absolute measures are at least as good as, if not better than, relative ones for informing rational decisions across choice scenarios. Specifically, this dominance of absolute measures holds for choices between a treatment and a control group treatment from a trial and for ones between treatments tested in different trials. This distinction has hitherto been neglected, just like the role of absolute and (...) baseline risks in rational decision-making that my analysis reveals. Recognizing both aspects advances the discussion on reporting outcome measures. (shrink)

The essay collection "Kant on Proofs for God's Existence" provides a highly needed, comprehensive analysis of the radical turns of Kant's views on proofs for God's existence.— In the "Theory of Heavens" (1755), Kant intends to harmonize the Newtonian laws of motion with a physico-theological argument for the existence of God. But only a few years later, in the "Ground of Proof" essay (1763), Kant defends an ontological ('possibility' or 'modal') argument on the basis of its logical exactitude while he (...) praises the physico-theological argument for its beauty and appeal to the common sense. In the first "Critique" (1781/7), Kant replaces traditional constitutive ontological, cosmological, and physico-theological proofs with his own regulative theoretical and moral-practical religious arguments. He continues to defend a moral argument in the second "Critique" (1788). But in the third "Critique" (1790), Kant reintroduces a physico-theological besides an ethicotheological argument in order to unify the critical system of philosophy. Kant develops further moral arguments and arguments from evil in the "Theodicy" essay (1791) and the "Religion" (1793/4), and still searches for the right kind of proof for God's existence in the "Opus postumum" (1796–1804).—Part one of this volume is dedicated to an analysis of Kant's proofs for God's existence in their historical order that explains which proofs Kant favors or rejects in various periods of his thought. Part two contains a systematic classification of main kinds of proof for God's existence in Kant that outlines the argumentative structure of particular kinds of proof and discusses Kant's potential reasons for their variations and modifications. The essay collection speaks to Kant specialists, philosophers, and theologians, but introduces the topic to non-academic readers also. -/- Contributers: Uygar Abaci (Pennsylvania State University), Craig Bacon (University of South Carolina), Andrew Chignell (Princeton University), Eckart Förster (Humboldt University, Johns Hopkins University), Ina Goy (Beijing Normal University) Paul Guyer (Brown University), Graham Oppy (Monash University), Lara Ostaric (Temple University), Stephen Palmquist (Independent Scholar), Lawrence Pasternack (Oklahoma State University), Konstantin Pollok (University of Mainz), Oliver Sensen (University of Tulane), Allen Wood (Bloomington University, Stanford University). (shrink)

This chapter examines Kant's account of the nature of nonhuman and human animals in the "Critique of the Power of Judgement". It discusses how Kant thought that a complete account of the forms of explanation commit one to belief in God. It concludes, firstly, that Kant's account implies an unhealthy anthropocentrism and an Enlightenment prejudice in the form of the overestimation of reason, and secondly, that the Kantian model of God lacks one of the main characteristics of the Christian conception (...) of God: the universal divine love, a power that unifies and embraces all beings, including nonhuman and human animals and their orders. (shrink)

Food security is becoming an increasingly relevant topic in the Global North, especially in urban areas. Because such areas do not always have good access to nutritionally adequate food, the question of how to supply them is an urgent priority in order to maintain a healthy population. Urban and peri-urban agriculture, as sources of local fresh food, could play an important role. Whereas some scholars do not differentiate between peri-urban and urban agriculture, seeing them as a single entity, our hypothesis (...) is that they are distinct, and that this has important consequences for food security and other issues. This has knock-on effects for food system planning and has not yet been appropriately analysed. The objectives of this study are to provide a systematic understanding of urban and peri-urban agriculture in the Global North, showing their similarities and differences, and to analyse their impact on urban food security. To this end, an extensive literature review was conducted, resulting in the identification and comparison of their spatial, ecological and socio-economic characteristics. The findings are discussed in terms of their impact on food security in relation to the four levels of the food system: food production, processing, distribution and consumption. The results show that urban and peri-urban agriculture in the Global North indeed differ in most of their characteristics and consequently also in their ability to meet the food needs of urban inhabitants. While urban agriculture still meets food needs mainly at the household level, peri-urban agriculture can provide larger quantities and has broader distribution pathways, giving it a separate status in terms of food security. Nevertheless, both possess (unused) potential, making them valuable for urban food planning, and both face similar threats regarding urbanisation pressures, necessitating adequate planning measures. (shrink)

Based on field research on Andean medicine men and West Tibetan (Ladakhi) shamans, this paper delineates some research problems which arise from the lies told and amnesia experienced by indigenous informants. It is shown that the problem of amnesia leads to the paradox that "one can only do research on shamans by ceasing to do research." In discussing four hypotheses for understanding shaman's amnesia, as a "lie," as a professional ideology, or as an artifact of Western research, a solution is (...) sought for this paradox. The best solution is seen in an approach called "recycling the waste" in which lies, inventions, contradictory and fragmentary information (usually considered as the "waste" of research) are being "recycled" as valuable data in their own right. (shrink)

GPs usually care for their patients for an extended period of time, therefore, requests to not only discontinue a patient’s treatment but to assist a patient in a suicide are likely to create intensely stressful situations for physicians. However, in order to ensure the best patient care possible, the competent communication about the option of physician assisted suicide as well as the assessment of the origin and sincerity of the request are very important. This is especially true, since patients’ requests (...) for PAS can also be an indicator for unmet needs or concerns. Twenty-three qualitative semi-structured interviews were conducted to in-depth explore this multifaceted, complex topic while enabling GPs to express possible difficulties when being asked for assistance. The analysis of the gathered data shows three main themes why GPs may find it difficult to professionally communicate about PAS: concerns for their own psychological well-being, conflicting personal values or their understanding of their professional role. In the discussion part of this paper we re-assess these different themes in order to ethically discuss and analyse how potential barriers to professional communication concerning PAS could be overcome. (shrink)

In this contribution, Andrew Arato and Jean Cohen’s Populism and Civil Society is confronted with current gender studies research on populism. This research mainly focuses on right-wing populism and highlights strong links between right-wing populists and the religious right, which are to a large degree organized by “anti-gender,” a stance both against social constructivist notions of gender and against basic gender rights, especially in the fields of reproduction and of LGBTIQ concerns. Against the backdrop of this literature, I argue that (...) in Populism and Civil Society, right-wing populist anti-gender politics are not addressed in a way that takes account of their full complexity; and that these politics furthermore suggest to treat right-wing populism and left-wing populism as phenomena that do not only differ in content, but also in form. (shrink)

In Arthur Danto’s The Seat of the Soul: Three Chairs, the chair is a source of power and authority. This paper explores the aesthetic importance of chairs and their designers and determines why people from various cultures create different designs that all perform the same function: seating. Here, the chair is examined as an artwork and design phenomenon from historical, cultural, stylistic, and aesthetic perspectives. Data were gathered through a comprehensive literature review, reports, archival materials, and museum visits. Descriptive, historical, (...) and analytical methods were used to explore the religious, symbolic, spiritual, artistic, competitive, and academic legacies of the chair. Despite the similarity in function, the chair is more important than a sofa, bed, or bench. It displays one’s status, education, knowledge, and artistic taste. However, practicality, low-cost materials, and money have trumped aesthetics in recent years. The findings may help young chair designers highlight their competitiveness and inventiveness. (shrink)

This article considers the sexual politics of animal evidence in the context of German sexology around 1920. In the 1910s, the German-Jewish geneticist Richard B. Goldschmidt conducted experiments on the moth Lymantria dispar, and discovered individuals that were no longer clearly identifiable as male or female. When he published an article tentatively arguing that his research on ‘intersex butterflies’ could be used to inform concurrent debates about human homosexuality, he triggered a flurry of responses from Berlin-based sexologists. In this article, (...) I examine how a number of well-known sexologists affiliated with Magnus Hirschfeld, his Scientific-Humanitarian Committee, and later his Institute of Sexology attempted to incorporate Goldschmidt’s experiments into their sexological work between 1917 and 1923. Intersex butterflies were used to discuss issues at the heart of German sexology: the legal debate about the criminalisation of homosexuality under paragraph 175; the scientific methodology of sexology, caught between psychiatric, biological, and sociological approaches to the study of sexual and gender diversity; and the status of sexology as natural science, able to contribute knowledge about the sexual Konstitution of the organism. This article thus shows that butterfly experiments function as important and politically charged evidence for a discussion at the heart of the sexological project of those involved in the founding of the Institute of Sexology: the question of the nature and naturalness of homosexuality (and sexual intermediacy more broadly) and its political consequences. In doing so, this article makes a case for paying attention to non-human actors in the history of sexology. (shrink)

In this paper, I will argue against Ginsborg's (2014) rejection of divine design in Kant's account of organisms that Kant develops a variety of physico-theological arguments throughout his career whereby he changes the premises of the physico-theological argument in accordance with his changing concepts of the order of nature. In the first part of the paper, I will reconstruct Kant’s ealier attempts to develop a valid physico-theological argument. While Kant recognizes marks of divine design in the unity of the major (...) mechanical orders of the macrocosmos in his early "Theory of the Heavens", in the "Ground of Proof" essay, Kant claims that marks of divine design appear in the unity of the highly complex minor mechanisms in the microcosmos also, in what he later calls ‘organized’ beings. But although the inclusion of organic orders as marks of divine design improves the strength of the physico-theological argument, Kant, as Hume before him, at the same time realizes its syllogistic defectiveness. Its main logical failure consists in the derivation of a non-empirical conclusion, the idea of God, from empirical premises, the observable beauty and order of nature. Consequently, Kant follows a destructive path in the first "Critique", now claiming that the physico-theological argument relies on the ontological argument, whereby the latter is false, and finally avoids the physico-theological argument in the second "Critique". But in the third "Critique", Kant reintroduces a new variant of the physico-theological argument beside the ethicotheological argument. Why so? I will argue in the second part of the paper, that Kant’s new attitude towards the physico-theological argument in the third "Critique" relies, again, on a new insight into the order of nature: Kant’s detection of teleological laws of nature and of the necessary unity of a natural purpose. Both allow Kant to no longer ground the physico-theological argument on a posteriori, empirical premises related to the mechanical macrocosmic or microcosmic orders of nature alone, but on a priori premises instead related to the teleological order of nature and the necessary unity of a natural purpose. The concept of the necessary unity of a natural purpose, though a posteriori and empirical, implies the non-empirical, a priori necessary unity of all properties that can be subordinate to the idea of a natural purpose. Moving the premise of the physico-theological argument from the empirical a posteriori into the non-empirical a priori realm enables Kant to close the logical gap in the earlier versions of his physico-theological argument and to validly derive a conclusion from the a priori moment in the notion of the designed to the a priori notion of its designer. But this argument is not without flaws either. (shrink)

ZusammenfassungDer Artikel skizziert die Grundlagen einer neuen Subdisziplin innerhalb der Religionswissenschaft, der Religionsethologie. Religionsethologie lässt sich letztlich auf Charles Darwin selbst zurückführen, der bereits in seinem Buch The expression of the emotions in man and animals belegen konnte, dass jede Form von Verhalten für das Überleben der Art genau so wichtig ist wie die Adaptation des Phänotypus. In den Geisteswissenschaften wurde der Darwinsche Ansatz sofort aufgegriffen und von bedeutenden Forschern wie Karl Meuli, Aby Warburg und in jüngerer Zeit von Roy (...) Rappaport, Marvin Harris und anderen aufgegriffen und fruchtbar gemacht, indem sie einerseits religiöse Universalien herausarbeiten, andererseits aber auch die Grundzüge einer religiösen Evolution darstellen konnten. Religion ist demnach tief in der Biologie des Menschen verwurzelt und kann demzufolge auch unter biologischen Gesichtspunkten erforscht werden. (shrink)

Animal, protist and viral messenger RNAs (mRNAs) are most prominently modified at the beginning by methylation of cap‐adjacent nucleotides at the 2′‐O‐position of the ribose (cOMe) by dedicated cap methyltransferases (CMTrs). If the first nucleotide of an mRNA is an adenosine, PCIF1 can methylate at the N6‐position (m6A), while internally the Mettl3/14 writer complex can methylate. These modifications are introduced co‐transcriptionally to affect many aspects of gene expression including localisation to synapses and local translation. Of particular interest, transcription start sites (...) of many genes are heterogeneous leading to sequence diversity at the beginning of mRNAs, which together with cOMe and m6Am could constitute an extensive novel layer of gene expression control. Given the role of cOMe and m6A in local gene expression at synapses and higher brain functions including learning and memory, such code could be implemented at the transcriptional level for lasting memories through local gene expression at synapses. (shrink)

The permanent preservation of objects in global custodianship is a captivating ideal that informs countless museums’ corporate identities and governs collection guidelines as well as politics. Recent research has challenged the alleged perpetuity of collections and collected items, revealing their coherence as fragile and dependent on historically, politically and culturally specific conditions. Duplicates offer an instructive point of entry to explore the idea of collection permanence, museum politics, and the mobility of museum objects. The history of duplicates, moreover, comprises a (...) constellation of practises, concepts and debates that can be found in various forms throughout the intertwined histories of natural-scientific, ethnographic and artistic collections. This history, however, has rarely been questioned or explored. By introducing the issue of duplicates, this paper opens up a discussion that not only connects different forms of collections, but also situates the history of collecting institutions across the disciplinary spectrum within broader political, economic and epistemic frameworks. (shrink)

Ein textnaher, fortlaufender Kommentar zu Kants Lehre von organisierten Wesen in der „Kritik der Urteilskraft“ ist ein Desiderat sowohl der Kantforschung als auch der Philosophie und Geschichte der Lebenswissenschaften. Auch gibt es bisher nur wenige Lesarten, die Kants Philosophie der Biologie im Ganzen erschließen und versuchen, sie in die vielschichtigen historischen Kontexte der frühneuzeitlichen Naturforschung einzuordnen. Das vorliegende Buch schließt diese Lücken. Es verteidigt die Thesen, dass Kant organisierte Wesen durch drei Arten von Kräften und Gesetzen charakterisiert – durch mechanische, (...) physisch teleologische und moralteleologische Krätfe und Gesetze – deren Vereinbarkeit im Bewusstsein des Menschen, und in der Erfahrungswelt, so, wie sie dem Menschen erscheint, auf der regulativen Idee ihrer Einheit im schöpferischen, theoretisch praktischen Bewusstsein Gottes beruht. Kants Lehre von organisierten Wesen kann als Verbindung einer gemäßigten, weder animalkulistisch noch ovistisch vereinseitigten, Präformationslehre mit einer vitalistischen Spielart der Epigenesislehre verstanden werden. – Weiterführende und provokative Einsichten für eine der bewegtesten Debatten der gegenwärtigen Kantforschung. (shrink)

Quando Brecht escreveu que o teatro épico pressupõe a posse dos meios de produção teatral pelo movimento operário, além de indicar as raízes históricas de suas opções estéticas, estava expondo um critério de añálise para o conjunto da produção teatral moderna. Já a tardia importação do teatro moderno pelos brasileiro foi patrocinada por uma burguesia desenvolvimentista geralmente ciosa da necessidade de cortar ou obscurecer os vínculos das obras passíveis de consumo local. Mas no final dos anos cinquenta vamos observar o (...) encontro entre forma importada e adaptada e demandas culturais que ultrapassavam os estreitos limites impostos ao nosso mercado teatral modernzado. (shrink)