Continuous and patient inflow of new human and financial resources by the government or by private industry based on the strong will of top management backed by the concensus of constituents of the organisation is the main factor which contributes to the prosperity of any technology.

The mitogenic action of cytokines such as epidermal growth factor (EGF)d̊ or platelet dericed growth factor (PDGF) involves the stimulation of a signal cascade controlled by a small G protein called Ras. Mutations of Ras can cause its constitutive activation and, as a consequence, bypass the regulation of cell growth by cytokines. Both growth factor‐induced and oncogenic activation of Ras involve the conversion of Ras from the GDP‐bound (D‐Ras) to the GTP‐bound (T‐Ras) forms. T‐Ras activates a network of protein kinases (...) including c‐Mos, c‐Raf‐1 and MAP kinase. Eventually the activation of MAP kinase leads to the activation of the elongation factor 4E and several transcription factors such as c‐Jun, c‐Myc and c‐Fos. There are several modulators of Ras activity, such as the GTPase activating proteins (GAP1 and NF1), which stimulate the coversion of T‐Ras to D‐Ras. A series of small NF1 fragments, which bind T‐Ras, as well as truncated forms or derivatives of c‐Raf‐1, c‐Jun and c‐Myc, are capable of blocking the T‐Ras‐activated mitogenesis in a competitive manner. These agents offer a unique opportunity to control the proliferation of T‐Ras‐associated tumors, which represent more than 30% of total human carcinomas. (shrink)

dai 1-kan. Ningen, kyōiku ga umarekawaru tame -- dai 2-kan. Ningen to no deai, kyōiku to no deai -- dai 3 kan. Ningenrashiku naru tedate -- dai 4-kan. Jinrui no kibō, osanago -- dai 5-kan. Shishū, ushinawareta kisetsu o motomete -- dai 6-kan. Aru mazushiki shōgai no kiroku -- [7] Kyōiku to kyōikugaku.

We study the relationship between the semistationary reflection principle and stationary reflection principles. We show that for all regular cardinals Λ ≥ ω₂ the semistationary reflection principle in the space [Λ](1) implies that every stationary subset of $E_{\omega}^{\lambda}\coloneq \{\alpha \in \lambda \,|\,{\rm cf}(\alpha)=\omega \}$ reflects. We also show that for all cardinals Λ ≥ ω₃ the semistationary reflection principle in [Λ](1) does not imply the stationary reflection principle in [Λ](1).

『日本唯物論史』などで知られるわが国の唯物論哲学の開拓者・永田廣志の生涯をまとめ、その理論活動の意義を解明。哲学研究者と在野の郷土史家との共同研究が生み出した成果。本邦初公開の貴重な資料や秘蔵写真も多 数紹介。.

It is known that there is a close relation between Prikry forcing and the iteration of ultrapowers: If U is a normal ultrafilter on a measurable cardinal κ and 〈Mn, jm,n | m ≤ n ≤ ω〉 is the iteration of ultrapowers of V by U, then the sequence of critical points 〈j0,n | n ∈ ω〉 is a Prikry generic sequence over Mω. In this paper we generalize this for normal precipitous filters.

It has been reported as a robust effect that people are likely to select a matching case in the Wason selection task. For example, they usually select the 5 case, in the Wason selection task with the conditional "if an E, then a not-5". This was explained by the matching bias account that people are likely to regard a matching case as relevant to the truth of the conditional (Evans, 1998). However, because a positive concept usually constructs a smaller set (...) than its negative one does (a rarity assumption), it is more effective to get information on the truth of the conditional in a positive set than in a negative set. Thus the optimal data selection account can also explain the effect. The set size of Q and matching by introducing negation were manipulated independently in four experiments. From the results it was inferred that the so-called matching bias was an amalgam of two different cognitive components-relevance judgement by matching and optimal data selection. (shrink)

The genesis for this volume was in the bombing of Japan during World War II, where the author, as a young boy, watched the bombers overhead, speculating about the lives of the pilots and their relationship with those huddled on the ground._ From this disturbing diorama, Professor Hiroshi Kojima, the translator of Martin Buber into Japanese, unfolds a new approach to Buber's “I-Thou” relation, drawing upon insights from Husserl, Heidegger, and others in the tradition of continental philosophy to extend (...) and deepen Buber's thought. In chapters that reflect upon a wide range of phenomena—from religion, science, and technology, to imagination, embodiment, and power—Professor Kojima articulates a conception of what it means to be a human being that stands as an alternative to atomism and alienation of the modern world. Analyses of haiku and other aspects of Japanese culture demonstrate how Kojima's theory can illuminate the spiritual traditions of both East and West. Original in its thought and revealing in its insight into Japanese thought and culture, _Monad and Thou__ represents the life's work of one of Japan's great thinkers. (shrink)

世界に日本文化として「禅の思想」を広めた鈴木大拙。彼の無二の親友であり近代日本が生み出した最大の哲学者といわれている、西田幾多郎。その、難解といわれる西田の思想を「普段の生活の中から掴み出し現実化し、 具体的な経験と結びつけて解き明かした」画期的入門書。.

We investigate how weak square principles are denied by Chang’s Conjecture and its generalizations. Among other things we prove that Chang’s Conjecture does not imply the failure of \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\square_{\omega_1, 2}}$$\end{document}, i.e. Chang’s Conjecture is consistent with \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\square_{\omega_1, 2}}$$\end{document}.

Minami–Sakai :883–898, 2016) investigated the cofinal types of the Katětov and the Katětov–Blass orders on the family of all \ ideals. In this paper we discuss these orders on analytic P-ideals and Borel ideals. We prove the following:The family of all analytic P-ideals has the largest element with respect to the Katětov and the Katětov–Blass orders.The family of all Borel ideals is countably upward directed with respect to the Katětov and the Katětov–Blass orders. In the course of the proof of (...) the latter result, we also prove that for any analytic ideal \ there is a Borel ideal \ with \. (shrink)

dai 1-kan. Hōgaku no kiso riron -- dai 2-kan. Gendai hōgaku no taikei. Kōhō, shakaihō -- dai 3-kan. Gendai hōgaku no taikei. Shihō, gaikokuhō.

The present work, which was inspired by Kripke and McCarthy, is about a non-classical predicate logic system containing a truth predicate symbol. In this system, each sentence A is referred to not by a Gödel number but by its quotation name 'A'.

It is important to manage individuals’ personal data after their death to maintain their dignity or follow their wishes as much as possible. From this perspective, this report describes the real-world commercialization of immortal digital personalities, which gives eternal life to the deceased in a digital form. We identify the problems with the commercialization of deceased users’ images and personal data, which becomes postmortem entertainment. Considering these problems, we seek out the ideal form of deceased users’ personal data for commercialization. (...) We conduct a social survey to understand how ordinary Japanese people feel about the various types of publicly available services that use personal data after death, such as social network service logs. By analyzing our survey results approximately 20% of respondents would allow the commercial use of their personal data, such as browsing their social network service logs, if they could receive compensation during their lifetime. (shrink)

In this paper we will study a formal system of intuitionistic modal predicate logic. The main result is its semantic completeness theorem with respect to algebraic structures. At the end of the paper we will also present a brief consideration of its syntactic relationships with some similar systems.

Does the psychoanalytic concept of narcissism contribute to enhancing the disciplinary quality and features of political theory? This book tries to portray the foundations of democracy as both a universal value and a system of values embedded in specific cultural systems of meaning from its psychoanalytic perspective. This cross-disciplinary normative attempt makes possible the constructive dialogue between contemporary Western and Japanese culture by focusing on how the psychological foundations of democracy are treated within a common disciplinary framework in two different (...) sociocultural contexts. In light of the integration of the psychiatrically mythical idea, the book argues that the key subjects of political theory are to identify the sources of totalitarian and fascist orientations in seemingly democratic practice, and to deal with them in psychoanalytically diagnostic and remedial terms. (shrink)