Taking Hobbesian logic as my starting point, I argue that Hobbesian diffidence, one of the causes of quarrel in the state of nature, does not disappear once the citizens enter civil society. Rather, diffidence is merely contained by the sovereign. Following Alice Ristroph, I argue that diffidence comes to shape what citizens demand of the state/sovereign in the criminal law. However, I show that Ristroph does not fully appreciate that the concept of diffidence is a racialized one, and as such, (...) race underlies how the citizens understand their own diffidence, what citizens demand of the sovereign, and how they demand it. Further, because diffidence itself is racialized, criminal law need not make explicit appeals to race. Once racialized diffidence becomes embedded in the criminal law, it remains there regardless of any conscious racial animus. I show that racial profiling is a prime example of how this racialized diffidence manifests. Thus, I present Hobbesian diffidence as a framework from which to understand racial oppression. This paper is primarily an application of Hobbes to contemporary issues rather than an exegesis and analysis of Hobbes’s views. (shrink)

welcomed by a new generation of students and scholars in all branches of learning.

This book consists in seventeen chapters devoted to physical, metaphysical, and methodological questions concerning open systems. The chapters in the volume address questions such as: Are (theories of) open systems more fundamental than (theories of) closed systems? How have concepts of open and closed systems have been used throughout the history of physics, and how should we understand their use in contemporary physical theories? Must the universe be a closed system? Must there be a such thing as the universe at (...) all? -/- Contributors: Emily Adlam, Luis C. Barbado, Caslav Brukner, Eddy Keming Chen, Michael E. Cuffaro, Gemma De les Coves, George Ellis, Doreen Fraser, Henrique Gomes, Sean Gryb, William L. Harper, Stephan Hartmann, Molly Kao, Adam Koberinski, James Ladyman, Simon Langenscheidt, Olimpia Lombardi, Jorn Klovfjell Mjelva, Wayne C. Myrvold, Daniele Oriti, Josh Quirke, David Sloan, Karim P. Y. Thebault, Lev Vaidman, David Wallace, and Alastair Wilson. (shrink)

"Biophilia" is the term coined by Edward O. Wilson to describe what he believes is humanity's innate affinity for the natural world. In his landmark book Biophilia, he examined how our tendency to focus on life and lifelike processes might be a biologically based need, integral to our development as individuals and as a species. That idea has caught the imagination of diverse thinkers. The Biophilia Hypothesis brings together the views of some of the most creative scientists of our (...) time, each attempting to amplify and refine the concept of biophilia. The variety of perspectives -- psychological, biological, cultural, symbolic, and aesthetic -- frame the theoretical issues by presenting empirical evidence that supports or refutes the hypothesis. Numerous examples illustrate the idea that biophilia and its converse, biophobia, have a genetic component: fear, and even full-blown phobias of snakes and spiders are quick to develop with very little negative reinforcement, while more threatening modern artifacts -- knives, guns, automobiles -- rarely elicit such a response people find trees that are climbable and have a broad, umbrella-like canopy more attractive than trees without these characteristics people would rather look at water, green vegetation, or flowers than built structures of glass and concrete The biophilia hypothesis, if substantiated, provides a powerful argument for the conservation of biological diversity. More important, it implies serious consequences for our well-being as society becomes further estranged from the natural world. Relentless environmental destruction could have a significant impact on our quality of life, not just materially but psychologically and even spiritually. (shrink)

Introduction: Depression, biology, aggression -- Underbelly -- The biological unconscious -- Bitter melancholy -- Chemical transference -- The bastard placebo -- The pharmakology of depression.

Philosophical exploration of individualism and externalism in the cognitive sciences most recently has been focused on general evaluations of these two views (Adams & Aizawa 2008, Rupert 2008, Wilson 2004, Clark 2008). Here we return to broaden an earlier phase of the debate between individualists and externalists about cognition, one that considered in detail particular theories, such as those in developmental psychology (Patterson 1991) and the computational theory of vision (Burge 1986, Segal 1989). Music cognition is an area in (...) the cognitive sciences that has received little attention from philosophers, though it has relatively recently been thrown into the externalist spotlight (Cochrane 2008, Kruger 2014, Kersten forthcoming). Given that individualism can be thought of as a kind of paradigm for research on cognition, we provide a brief overview of the field of music cognition and individualistic tendencies within the field (sections 2 and 3) before turning to consider externalist alternatives to individualistic paradigms (section 4-5) and then arguing for a qualified form of externalism about music cognition (section 6). (shrink)

Many contemporary philosophers accept Hume's Dictum, according to which there are no metaphysically necessary connections between distinct, intrinsically typed entities. Tacit in Lewis 's work is a potential motivation for HD, according to which one should accept HD as presupposed by the best account of the range of metaphysical possibilities---namely, a combinatorial account, applied to spatiotemporal fundamentalia. Here I elucidate and assess this Ludovician motivation for HD. After refining HD and surveying its key, recurrent role in Lewis ’s work, I (...) present Lewis ’s appeal to HD as providing a broadly axiomatic generating basis for the space of metaphysical modality, and canvas the prima facie advantages of the resulting combinatorial principle---HD ---as being principled, extensionally adequate and modally reductive. Most criticisms of Lewis 's combinatorialism have targeted seeming ways in which the theory overgenerates the desired space; I rather argue that HD seriously undergenerates the desired space in three different ways. For each way I argue that available means of overcoming the undergeneration either fail to close the gap, undermine the claim that HD is a principled generator of metaphysical modal space, undermine the reductive status of Lewis 's combinatorialism, or call into question the truth of HD. (shrink)

This paper considers ten questions that those puzzled by or skeptical of extended cognition have posed. Discussion of these questions ranges across substantive, methodological, and dialectical issues in the ongoing debate over extended cognition, such as whether the issue between proponents and opponents of extended cognition is merely semantic or a matter of convention; whether extended cognition should be treated in the same way as extended biology; and whether conscious mental states pose a special problem for the extended mind thesis. (...) Lethocerus, the giant water bug, will be a recurrent reference point for much of the discussion. (shrink)

In what does philosophical progress consist? 'Vertical' progress corresponds to development within a specific paradigm/framework for theorizing (of the sort associated, revolutions aside, with science); 'horizontal' progress corresponds to the identification and cultivation of diverse paradigms (of the sort associated, conservativism aside, with art and pure mathematics). Philosophical progress seems to involve both horizontal and vertical dimensions, in a way that is somewhat puzzling: philosophers work in a number of competing frameworks (like artists or mathematicians), while typically maintaining that only (...) one of these is correct (like scientists). I diagnose this situation as reflecting that we are presently quite far from the end of inquiry into philosophical methodology. The good news is that we appear to be making advances on this score. The bad news is that failure to recognize or make explicit that our standards are in flux often leads to dogmatism, as I illustrate by attention to three assumptions presently operative in metaphysical and metametaphysical contexts. I close by identifying a tension between vertical and horizontal progress in philosophy, and suggesting an updated version of Carnap's principle of tolerance for new philosophical forms. (shrink)

The nonlinearity of a composite system, whereby certain of its features (including powers and behaviors) cannot be seen as linear or other broadly additive combinations of features of the system's composing entities, has been frequently seen as a mark of metaphysical emergence, coupling the dependence of a composite system on an underlying system of composing entities with the composite system's ontological autonomy from its underlying system. But why think that nonlinearity is a mark of emergence, and moreover, of metaphysical rather (...) than merely epistemological emergence? Are there diverse ways in which nonlinearity might enter into an account of properly metaphysical emergence? And what are the prospects for there actually being phenomena that are metaphysically emergent in any available sense? Here I explore the mutual bearing of nonlinearity and metaphysical emergence, with an eye towards answering these and related questions. (shrink)

This volume presents twelve original essays on the metaphysics of science, with particular focus on the physics of chance and time. Experts in the field subject familiar approaches to searching critiques, and make bold new proposals in a number of key areas. Together, they set the agenda for future work on the subject.

This paper examines one of the historical antecedents of Big Data, the social physics movement. Its origins are in the scientific revolution of the 17th century in Western Europe. But it is not named as such until the middle of the 19th century, and not formally institutionalized until another hundred years later when it is associated with work by George Zipf and John Stewart. Social physics is marked by the belief that large-scale statistical measurement of social variables reveals underlying relational (...) patterns that can be explained by theories and laws found in natural science, and physics in particular. This larger epistemological position is known as monism, the idea that there is only one set of principles that applies to the explanation of both natural and social worlds. Social physics entered geography through the work of the mid-20th-century geographer William Warntz, who developed his own spatial version called “macrogeography.” It involved the computation of large data sets, made ever easier with the contemporaneous development of the computer, joined with the gravitational potential model. Our argument is that Warntz's concerns with numeracy, large data sets, machine-based computing power, relatively simple mathematical formulas drawn from natural science, and an isomorphism between natural and social worlds became grounds on which Big Data later staked its claim to knowledge; it is a past that has not yet passed. (shrink)

Several current debates in the epistemology of testimony are implicitly motivated by concerns about the reliability of rules for changing one’s beliefs in light of others’ claims. Call such rules testimonial norms (tns). To date, epistemologists have neither (i) characterized those features of communities that influence the reliability of tns, nor (ii) evaluated the reliability of tns as those features vary. These are the aims of this paper. I focus on scientific communities, where the transmission of highly specialized information is (...) both ubiquitous and critically important. Employing a formal model of scientific inquiry, I argue that miscommunication and the “communicative structure” of science strongly influence the reliability of tns, where reliability is made precise in three ways. (shrink)

Darren Bradley has recently appealed to observation selection effects to argue that conditionalization presents no special problem for Everettian quantum mechanics, and to defend the ‘halfer’ answer to the puzzle of Sleeping Beauty. I assess Bradley’s arguments and conclude that while he is right about confirmation in Everettian quantum mechanics, he is wrong about Sleeping Beauty. This result is doubly good news for Everettians: they can endorse Bayesian confirmation theory without qualification, but they are not thereby compelled to adopt the (...) unpopular ‘halfer’ answer in Sleeping Beauty. These considerations suggest that objective chance is playing an important and under-appreciated role in Sleeping Beauty. 1 Introduction2 Confirmation in Everettian Quantum Mechanics3 Sleeping Beauty4 The Selection Model5 Bradley’s Argument6 The Right Route to ⅓7 The Breakdown of the Analogy8 Alternative Diagnoses9 God’s Gambling Game10 Non-chancy Sleeping Beauty Cases11 Conclusion. (shrink)

This article addresses India's contemporary population control policies and practices as a form of gender violence perpetrated by the state and transnational actors against poor, Adivasi and Dalit women. It argues that rather than meeting the needs and demands of these women for access to safe contraception that they can control, the Indian state has targeted them for coercive mass sterilisations and unsafe injectable contraceptives. This is made possible by the long-term construction of particular women's lives as devalued and disposable, (...) and of their bodies as excessively fertile and therefore inimical to development and progress. It further considers how population policy is currently embedded in the neoliberal framework of development being pursued by the Indian state. In particular, it argues that the violence of population policies is being deepened as a result of three central and interrelated aspects of this framework: corporate dispossession and displacement, the intensification and extension of women's labour for global capital, and the discourses and embodied practices of far-right Hindu supremacism. At the same time, India's population policies cannot be understood in isolation from the global population control establishment, which is increasingly corporate-led, and from broader structures of racialised global capital accumulation. The violence of India's contemporary population policies and the practices they produce operate at several different scales, all of which involve the construction of certain bodies as unfit to reproduce and requiring intervention and control. (shrink)

Explanations in physics commonly appeal to data drawn from different length or time scales, as when a “top-down” macroscopic constraint such as rigidity is used to evade the complexities one would confront in attempting to model the situation in a purely “bottom-up” fashion. Such techniques commonly embody rather complex shifts in explanatory strategy.

In medicine and the social sciences, researchers must frequently integrate the findings of many observational studies, which measure overlapping collections of variables. For instance, learning how to prevent obesity requires combining studies that investigate obesity and diet with others that investigate obesity and exercise. Recently developed causal discovery algorithms provide techniques for integrating many studies, but little is known about what can be learned from such algorithms. This article argues that there are causal facts that one could learn by conducting (...) a large study but which could not be learned by combining many smaller studies. Moreover, I characterize the frequency with which combining many studies increases underdetermination and exactly how much information is lost. 1 Introduction2 Causal Inference from Observational Data3 Piecemeal Causal Inference4 The Extent and Frequency of the Problem of Piecemeal Induction5 Conclusion. (shrink)

This is one of those cases to which Dr. 8 oodhouse's remark applies with all its force, that a method which leads to true results must have its logic — H.S Smith (" On Some of the Methods at Present in Use in Pure Geometry," p. 6) A goodly amount of modern metaphysics has concerned itself, in one form or another, with the question: what attitude should we take in regard to a language whose semantic underpinnings seem less than certain? (...) Since much of standard English is surely of this type, many philosophers have felt driven to extreme and unpalatable resolutions — wholesale rejection of attractive logical rules, radical "antirealism", "minimalism" about truth, and so forth, Scientists, however, have long dealt with analogous foundational insecurities and, under the duress of practicality, have framed a set of shifting attitudes towards language and reasoning that seem far more commonsensical than the extreme positions to which pure philosophy has often been led. Following this lead, this essay will recommend a more nuanced approach to linguistic insecurity that is neither naively optimistic nor mired in the gloomy sloughs of antirealism. (shrink)

These sixty contributions from researchers in ethology, ecology, cybernetics, artificial intelligence, robotics, and related fields delve into the behaviors and underlying mechanisms that allow animals and, potentially, robots to adapt and survive in uncertain environments. They focus in particular on simulation models in order to help characterize and compare various organizational principles or architectures capable of inducing adaptive behavior in real or artificial animals. Jean-Arcady Meyer is Director of Research at CNRS, Paris. Stewart W. Wilson is a Scientist at (...) The Rowland Institute for Science, Cambridge, Massachusetts. (shrink)

Cooperation can evolve in the context of cognitive activities such as perception, attention, memory, and decision making, in addition to physical activities such as hunting, gathering, warfare, and childcare. The social insects are well known to cooperate on both physical and cognitive tasks, but the idea of cognitive cooperation in humans has not received widespread attention or systematic study. The traditional psychological literature often gives the impression that groups are dysfunctional cognitive units, while evolutionary psychologists have so far studied cognition (...) primarily at the individual level. We present two experiments that demonstrate the superiority of thinking in groups, but only for tasks that are sufficiently challenging to exceed the capacity of individuals. One of the experiments is in a brain-storming format, where advantages of real groups over nominal groups have been notoriously difficult to demonstrate. Cognitive cooperation might often operate beneath conscious awareness and take place without the need for overt training, as evolutionary psychologists have stressed for individual-level cognitive adaptations. In general, cognitive cooperation should be a central subject in human evolutionary psychology, as it already is in the study of the social insects. (shrink)

A review, with reflections, of Michael S. Gazzaniga's (2011) book, Who's in Charge? Free Will and the Science of the Brain. Gazzaniga, a distinguished neuroscientist, wishes to connect contemporary understandings of the functioning of the human brain to the proper functioning of the American courtroom. What effect, if any, should these current understandings (and current technologies) have on legal conceptions of personal responsibility, guilt, and punishment? If, as many neuroscientists hold, the functioning of the brain wholly determines the functioning of (...) the mind, can people rightly be held responsible for their actions? Gazzaniga argues that they can. (shrink)

The fast–slow paradigm of life history focuses on how individuals grow, mate, and reproduce at different paces. This paradigm can contribute substantially to the field of personality and individual differences provided that it is more strictly based on evolutionary biology than it has been so far. Our study tested the existence of a fast–slow continuum underlying indicators of reproductive effort—offspring output, age at first reproduction, number and stability of sexual partners—in 1,043 outpatients with healthy to severely disordered personalities. Two axes (...) emerged reflecting a double-track pathway to fast strategy, based on restricted and unrestricted sociosexual strategies. When rotated, the fast–slow and sociosexuality axes turned out to be independent. Contrary to expectations, neither somatic effort—investment in status, material resources, social capital, and maintenance/survival—was aligned with reproductive effort, nor a clear tradeoff between current and future reproduction was evident. Finally, we examined the association of LH axes with seven high-order personality pathology traits: negative emotionality, impulsivity, antagonism, persistence-compulsivity, subordination, and psychoticism. Persistent and disinhibited subjects appeared as fast-restricted and fast-unrestricted strategists, respectively, whereas asocial subjects were slow strategists. Associations of LH traits with each other and with personality are far more complex than usually assumed in evolutionary psychology. (shrink)

Medical tourism describes a new pattern of movement of people for medical care, particularly from wealthier to poorer countries. Using the example of Thailand, where annually a million non-Thai patients seek medical treatment, this article provides a critical analysis of the political economic contexts for this medical migration. Drawing on urban geography and heterodox economics, the article considers medical tourism as an interaction of bodily, national, and global scales shaped by processes of globalization. This approach provides a thick context for (...) the transnational care of bodies while proposing that the bodily scale also has a role in reformulating the scale of the nation. (shrink)

Enhancer detectors are DNA constructs which, when introduced into a eukaryotic genome, respond to nearby genomic transcriptional regulatory elements by means of a reporter gene, revealing the expression pattern of genes in their vicinity. Recent experiments in Drosophila suggest that enhancer detection is a powerful method to identify genes that are expressed in the nervous system. Since enhancer detectors allow a rapid molecular and genetic characterization of genes in their vicinity, the method will greatly facilitate the study of neural development (...) and behavior. (shrink)

University of Minnesota Pamphlets on American Writers ; No. 88.

Several recent systematic and targeted reviews have highlighted limitations in our understanding of talent in sport. However, a comprehensive profile of where the scientific research has focused would help identify gaps in current knowledge. Our goal in this scoping review was to better understand what others have done in the field of research, to summarize the constituent areas of research in a meaningful way, to help identify gaps in the research, and to encourage future research to address these gaps. Peer-reviewed (...) articles written in English that met several inclusion criteria were analyzed. A total of 1,899 articles were identified, and the descriptive findings revealed a relatively narrow focus of research on talent in sport. Specifically, the majority of examined articles focused on males only, the sport of soccer, perceptual cognitive variables, developing athletes, adult samples, and cross-sectional designs. For better or worse, the concept of talent remains a central element of how coaches, practitioners, and scientists think about athlete development. Findings from this scoping review highlight the continued need to explore issues related to talent identification, selection, and development in more diverse samples and contexts. There is also a clear necessity to focus on under-researched areas using alternative methodologies. (shrink)

Manifesting the special intelligence of a literary critic of original gifts, Culture and Anarchy is still a living classic. It is addressed to the flexible and the disinterested, to those who are not committed to the findings of their particular discipline, and it assumes in its reader a critical intelligence that will begin its work with the reader himself. Arnold employs a delicate and stringent irony in an examination of the society of his time: a rapidly expanding industrial society, just (...) beginning to accustom itself to the changes in its institutions that the pace of its own development called for. Coming virtually at the end of the decade and immediately prior to W. E. Forster's Education Act, Culture and Anarchy phrases with a particular cogency the problems that find their centre in the questions: what kind of life do we think individuals in mass societies should be assisted to lead? How may we best ensure that the quality of their living is not impoverished? Arnold applies himself to the detail of his time: to the case of Mr Smith 'who feared he would come to poverty and be eternally lost', to the Reform agitation, to the commercial values that working people were encouraged to respect, and to the limitations of even the best Rationalist intelligence. The degree of local reference is therefore high, but John Dover Wilson's introduction and notes to this edition supply valuable assistance to a reader fresh to the period. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:George M. Wilson EDWARD SAID ON CONTRAPUNTAL READING Edward Said's rich and powerful new book, Culture and Imperialism,1 offers, as one strand of its multifaceted discussion, methodological reflections on the reading and interpretation of works of narrative fiction. More specifically, Said delineates and defends what he calls a "contrapuntal" reading (or analysis) ofthe texts in question. I am sympathetic to much ofwhat Said aims to accomplish in tiiis (...) endeavor, but I am also puzzled about some key aspects of his proposal. I will begin by presenting a brief sketch of my understanding of what a contrapuntal reading involves, and I will tiien explain some of the doubts and puzzlement I feel. Unfortunately, there is much that Said says about even diis limited topic that I will have to by-pass, but I hope to say enough to initiate some helpful discussion of the issues. I should note that aldiough the topic of "contrapuntal reading" recurs with significant emphasis throughout his book, Said's direct explication of the enterprise is scattered across several chapters, and the relevant remarks tend to be, in each instance, fairly brief. Given this state of affairs, I have tried to extract a reasonably unified account from a wide range of passages, and I hope to have done so as sympadietically and accurately as possible. Nevertheless, die fact remains that what follows is my reconstruction of the view diat Said adumbrates. Contrapuntal readings are meant to interweave, mutually qualify, and above all, superimpose die legitimate claims ofinternal or intrinsic readings of a work, on the one hand, and the claims ofvarious forms of external critique, on the odier. Such readings rest upon the fact that any literary fiction refers to or depicts a complex of materials that have been drawn from the actual world, e.g., actual people, places, institutions, and practices. These items are taken up and variously deployed Philosophy and Literature, © 1994, 18: 265-273 266Philosophy and Literature within the wider imaginative project of the work. It is crucial to this deployment tiiat the intended audience can be expected to bring to the text a set of background "attitudes" concerning die relevant real world materials, and tiiat diese beliefs, concerns, ideological presuppositions, etc., are elaborated widiin die work's embedded patterns. Thus, die text is anchored in what Said calls "a structure of reference and attitude," and diis structure constitutes die base from which a contrapuntal reading chiefly proceeds. Reading contrapuntally, interpreters move back and forth between an internal and external standpoint on the work's imaginative project, with special attention to the structure of reference and attitudes it contains. From an internal standpoint, interpretation aims at explanation of the work's narrational, rhetorical, and linguistic strategies, an explanation that respects the strategies and die density of the textual elements tiiey implicate. It is important that the internal standpoint articulate die work's vision as compellingly as possible, not only because diis has an obvious interest of its own, but because the persuasiveness ofcommentary from an external standpoint depends upon giving full credit to the sophistication of the text. (We will return to diis point shortly.) An external standpoint examines the problematic seductiveness of die work's capacity to guide its audience's responses and seeks to define die limited degrees of freedom widiin whatever complexity it establishes. By reminding us of information about the structure of reference that die work ignores, distorts, or minimizes and by reminding us that the structure of invoked attitudes has plausible alternatives that the work has effectively excluded, die external standpoint situates the text critically within a wider field of imaginative possibilities. As Said formulates the point, we read from an external perspective "... with an effort to draw out, extend, give emphasis and voice to what is silent or marginally present or ideologically represented" in die work" (CUfI, p. 66). In elaborating the account above, I have spoken of "intrinsic readings " of narrative fictions, and it will help to fill in my sketch if I specify the fairly standard conception I have in mind. Said does not address diis as a separate topic, but I believe that die following remarks are fully compatible with what he seems... (shrink)

Free Will: Art and Power on Shakespeare's Stage is a study of theatre and sovereignty that situates Shakespeare's plays in the contraflow between two absolutisms of early modern England: the aesthetic and the political. Starting from the dramatist's cringing relations with his princely patrons, Richard Wilson considers the ways in which this 'bending author' identifies freedom in failure and power in weakness by staging the endgames of a sovereignty that begs to be set free from itself. The arc of (...) Shakespeare's career becomes in this comprehensive new interpretation a sustained resistance to both the institutions of sacred kingship and literary autonomy that were emerging in his time. In a sequence of close material readings, Free Will shows how the plays instead turn command performances into celebrations of an art without sovereignty, which might 'give delight' but 'hurt not', and 'leave not a rack behind'. Free Will is a profound rereading of Shakespeare, art and power that will contribute to thinking not only about the plays, but also about aesthetics, modernity, sovereignty and violence. (shrink)

In The Age of Defeat, the third volume of the Outsider Cycle, Colin Wilson introduces his New Existentialism as the basis for the revolution in thought that we need to bring about; a revolt against insignificance and ordinariness. The New Existentialism is a practical and strong-willed philosophy that will renew the concept of Man as hero. It emphasises the extraordinary in us.The Age of Defeat examines the loss of the hero in Western culture and the implications of that loss (...) for humanity. When it was written in the middle of the 20th century, it was the idea of the hero that was endangered. Today it is Man, his identity and his masculinity, who is verging on extinction. The concept of Man is one of the most ambiguous and puzzling in our culture. It might be a good moment to remember what to be a Man used to imply. (shrink)

In many species the mutation rate is higher in males than in females, a phenomenon denoted as male mutation bias. This is often observed in animals where males produce many more sperm than females produce eggs, and is thought to result from differences in the number of replication‐associated mutations accumulated in each sex. Thus, studies of male mutation bias have the capacity to reveal information about the replication‐dependent or replication‐independent nature of different mutations. The availability of whole genome sequences for (...) many species, as well as for multiple individuals within a species, has opened the door to studying factors, both sequence‐specific and those acting on the genome globally, that affect differences in mutation rates between males and females. Here, we assess the advantages that genomic sequences provide for studies of male mutation bias and general mutation mechanisms, discuss major challenges left unresolved, and speculate about the direction of future studies. (shrink)