The current ethical structure for collaborative international health research stems largely from developed countries' standards of proper ethical practices. The result is that ethical committees in developing countries are required to adhere to standards that might impose practices that conflict with local culture and unintended interpretations of ethics, treatments, and research. This paper presents a case example of a joint international research project that successfully established inclusive ethical review processes as well as other groundwork and components necessary for the conduct (...) of human behavior research and research capacity building in the host country. (shrink)

Genetic database initiatives have given rise to considerable debate about their potential harms and benefits. The question arises as to whether existing ethical frameworks are sufficient to mediate between the competing interests at stake. One approach is to strengthen mechanisms for obtaining informed consent and for protecting confidentiality. However, there is increasing interest in other ethical frameworks, involving solidarity — participation in research for the common good — and the sharing of the benefits of research.

Genetic research has moved from Mendelian genetics to sequence maps to the study of natural human genetic variation at the level of the genome. This past decade of discovery has been accompanied by a shift in emphasis towards the ethical principles of reciprocity, mutuality, solidarity, citizenry and universality.

The demand for bodily parts such as organs is increasing, and individuals in certain circumstances are responding by offering parts of their bodies for sale. Is there anything wrong in this? Kant had arguments to suggest that there is, namely that we have duties towards our own bodies, among which is the duty not to sell parts of them. Kant's reasons for holding this view are examined, and found to depend on a notion of what is intrinsically degrading. Rom Harré's (...) recent revision of Kant's argument, in terms of an obligation to preserve the body's organic integrity, is considered. Harré's view does not rule out all acts of selling, but he too ultimately depends on a test of what is intrinsically degrading. Both his view and Kant's are rejected in favour of a view which argues that it does make sense to speak of duties towards our own bodies, grounded in the duty to promote the flourishing of human beings, including ourselves. This provides a reason for opposing the sale of bodily parts, and the current trend towards the market ethic in health care provision. (shrink)

Management plays an important role in reinforcing ethics in organizations. To support this aim, managers must use incentive and goal programs in ethical ways. This study examines experimentally the potential ethical costs associated with incentive-driven and goal-induced employee behavior from a managerial perspective. In a quasi-experimental setting, 243 MBA students with significant professional work experience evaluated a hypothetical employee’s ethical behavior under incentive pay systems modeled on a business case. In the role of the employee’s manager, participants evaluated the ethicality (...) of the employee’s incentive-driven and goal-induced ethical/unethical behavior and the outcomes of behavior, with consequences that were either favorable or unfavorable to the organization. The results indicated that participants discounted the ethical considerations of incentive-driven and goal-induced behavior when consequences were favorable to the organization. Participants’ morals and outcome orientations were also significantly related to their ethical judgments and intentions to intervene. The implications of these findings for research and practice are discussed. (shrink)

The question of what counts as a successful outcome of the process of genetics counselling has recently become central because of the increasing calls for efficiency in health care, and for means of measuring efficiency. Angus Clarke has drawn attention to this trend, and has argued against both a measure in terms of the number of terminations of pregnancy performed as a result of counselling, and an assessment in terms of the contribution of genetics counselling to a national eugenics policy. (...) He suggests instead a measure of workload. There are good arguments for supporting Clarke's position up to a point. In looking for an appropriate measure, much turns on how genetics counselling is defined. It is here understood in the context of an autonomy model of health care. It is argued that there is a contradiction between such an interpretation and the termination measure of outcome. The political philosophy underlying this outcome is also defective. Workload is not sufficient as a measure of outcome however; it is essential to look at the proper goals of an activity. It is argued that these must be connected in some way with the genetic health of the population; that the promotion of reproductive autonomy itself is not sufficient as a goal. The concern for genetic health, however, is interpreted in a way that avoids Clarke's concerns about a national eugenics policy. (shrink)

Theories of language production propose that utterances are constructed by a mechanism that separates linguistic content from linguistic structure, Linguistic content is retrieved from the mental lexicon, and is then inserted into slots in linguistic structures or frames. Support for this kind of model at the phonological level comes from patterns of phonological speech errors. W present an alternative account of these patterns using a connectionist or parallel distributed proceesing (PDP) model that learns to produce sequences of phonological features. The (...) model's errors exhibit some of the properties of human speech errors, specifically, properties that have been attributed to the action of phonological rules, frames, or other structural generalizations. (shrink)

This paper examines the ethical and legal duties of confidentiality owed by the nurse, with special reference to obligation to the employer. The main focus is on exploring the parameters of that duty and determining circumstances in which it might be ethically and legally justifiable to disclose confidential information. It is submitted that the obli gation to preserve the confidence of the patient or employer is relative rather than abso lute. In exceptional cases, disclosure is permissible in order to prevent (...) harm to others or to promote a greater public good. A number of suggestions for reform are also made, with a view to reinforcing nurses' ethical and legal rights to exercise discretion to dis close confidential information in appropriate cases in order to protect themselves from victimization by employers. Cet article passe à l'examen les devoirs éthiques et légales de la confidence que les infirmiers/ères doivent obligatoirement à leur employeur. Le point de mire est l'exploration des donnés de cette obligation, et la détermination des circonstances dans lesquelles il est légitime, éthiquement et légalement, d'exposer de l'information confidentielle. Il est suggéré que l'obligation de préserver la confiance du malade ou de l'employeur est relative plutôt qu'absolu. Dans des cas exceptionels pourtant, la révélation d'information est permisible pour prévenir le mal des autres ou pour promouvoir un plus grand bien public. Quelques suggestions pour réformes sont proposées en vue du renforcement des droits éthiques et légales des infirmiers/ères d'exercer la discretion en ce qui concerne la révélation d'information dans des cas bien choisis, et de les protéger des représailles de l'employeur. Dieser Artikel prüft die ethischen und legalen Pflichten des Vertrauens, die das Pflegepersonal dem Arbeitsgeber schuldet. Das Zentrum des Arguments ist eine Untersuchung dieser Pflichten, und eine Festsetzung der Umstände, in welchen es ethisch und rechtlich möglich ist, Information bekannt zu machen. Es ist anerkennt, dass die Pflicht des Vertrauens des Patienten oder des Arbeitsgebers zu behalten, eher relativ als absolut ist. In aussergewöhnlichen Fällen jedoch ist die Bekanntgabe von Information erlaubt, um das Böse zu verhindern und das Gute aller zu fördern. Eine Anzahl von Vorschlägen für Reformen sind gemacht, mit der Absicht, die ethischen und legalen Rechte des Pflegepersonals, in gegebenen Fällen Information bekannt zu machen, zu verstärken, und es von ungerechter Behandlung eines Arbeitsgebers zu schützen. (shrink)

The current study used cross-modal oddball tasks to examine cardiac and behavioral responses to changing auditory and visual information. When instructed to press the same button for auditory and visual oddballs, auditory dominance was found with cross-modal presentation slowing down visual response times more than auditory response times (Experiment 1). When instructed to make separate responses to auditory and visual oddballs, visual dominance was found with cross-modal presentation decreasing auditory discrimination and participants also made more visual-based than auditory-based errors on (...) cross-modal trials (Experiment 2). Experiment 3 increased task demands while requiring a single button press and found evidence of auditory dominance, suggesting that it is unlikely that increased task demands can account for the reversal in Experiment 2. Auditory processing speed was the best predictor of auditory dominance, with auditory dominance being stronger in participants who were slower at processing the sounds, whereas, auditory and visual processing speed and baseline heart rate variability did not predict visual dominance. Examination of cardiac responses that were time-locked with stimulus onset showed cross-modal facilitation effects, with auditory and visual discrimination occurring earlier in the course of processing in the cross-modal condition than in the unimodal conditions. The current findings showing that response demand manipulations reversed modality dominance and that time-locked cardiac responses show cross-modal facilitation, not interference, suggest that auditory and visual dominance effects may both be occurring later in the course of processing, not from disrupted encoding. (shrink)

Sociology requires a robust theory of how local circumstances create social order. When we analyze social structures not recognizing that they depend on groups with collective pasts and futures that are spatially situated and that are based on personal relations, we avoid a core sociological dimension: the importance of local context in constituting social worlds. Too often this has been the sociological stance, both in micro-sociological studies that examine interaction as untethered from local traditions and in research that treats culture (...) as autonomous from action and choice. Building on theories of action, group dynamics, and micro-cultures, I argue that a sociology of the local solves critical theoretical problems. The local is a stage on which social order gets produced and a lens for understanding how particular forms of action are selected. Treating ethnographic studies as readings of ongoing cultures, I examine how the continuing and referential features of group life (spatial arenas, relations, shared pasts) generate action and argue that local practices provide the basis for cultural extension, influencing societal expectations through the linkages among groups. (shrink)

Every body cell of an animal or human being contains the same complete set of genes. In theory any of these cells can be used to start a new embryo. The technique has been employed in the case of frogs. The nucleus is taken out of a body cell of a frog and implanted in an enucleated frog's egg. The resulting egg cell is stimulated to develop into a normal frog, and will be an exact copy of that frog which (...) provided the nucleus with all the genetic information. In normal sexual reproduction, two parents each contribute half their genes, but in the case of cloning, one parent passes on all his or her genes. (shrink)

Theories of language production have long been expressed as connectionist models. We outline the issues and challenges that must be addressed by connectionist models of lexical access and grammatical encoding, and review three recent models. The models illustrate the value of an interactive activation approach to lexical access in production, the need for sequential output in both phonological and grammatical encoding, and the potential for accounting for structural effects on errors and structural priming from learning.

The term “industrial action” includes any noncooperation with management, such as strict “working to rule,” refusal of certain duties, going slow, and ultimately withdrawal of labor. The latter form of action, striking, has posed particular problems for professional ethics, especially in those professions that provide healthcare, because of the potential impact on patients' well-being. Examination of the issues, however, displays a difference in response between the healthcare professions, in particular between doctors and nurses. In considering the ethics of industrial (especially (...) strike) action there are various aspects of professional ethics to consider: (1) whether there is a tension between industrial action and the very notion of professional ethics; (2) what specific issues arise in the case of healthcare professions; (3) what, if anything, can explain and/or justify different responses from the medical and nursing professions? (shrink)

There is no doubt science is currently suffering from a credibility crisis. This thought-provoking book argues that, ironically, science's credibility is being undermined by tools created by scientists themselves. Scientific disinformation and damaging conspiracy theories are rife because of the internet that science created, the scientific demand for empirical evidence and statistical significance leads to data torturing and confirmation bias, and data mining is fuelled by the technological advances in Big Data and the development of ever-increasingly powerfulcomputers. Using a wide (...) range of entertaining examples, this fascinating book examines the impacts of society's growing distrust of science, and ultimately provides constructive suggestions for restoring the credibility of the scientific community. (shrink)

The Principles of Fair Information Practice are almost three decades old and need to be broadened to take account of new technologies for collecting personal information such as drug testing, video cameras, electronic location monitoring and the internet. I argue that the ethics of surveillance activity must be judged according to the means, the context and conditions of data collection and the uses/goals and suggest 29 questions related to this. The more one can answer these questions in a way that (...) affirms the underlying principle the more ethical the use of a tactic is likely to be. Four conditions are identified which, when breached, are likely to violate an individual's reasonable expectation of privacy. Respect for the dignity of the person is a central factor and emphasis is put on the avoidance of harm, validity, trust, notice and permission when crossing personal borders. (shrink)

The apparent very close similarity between the learning of the past tense by Adam and the Plunkett and Marchman model is exaggerated by several misleading comparisons--including arbitrary, unexplained changes in how graphs were plotted. The model's development differs from Adam's in three important ways: Children show a U-shaped sequence of development which does not depend on abrupt changes in input; U-shaped development in the simulation occurs only after an abrupt change in training regimen. Children overregularize vowel-change verbs more than no-change (...) verbs; the simulation overregularizes vowel-change verbs less often than no-change verbs. Children, including Adam, overregularize more than they irregularize; the simulation overregularized less than it irregularized. Interestingly, the RM model--widely criticized as being inadequate--does somewhat better, correctly overregularizing vowel-change verbs more often than no-change verbs, and overregularizing more often than it irregularizes. Although Plunkett and Marchman's (1993) state of the art model incorporated hidden layers and back-propagation, used a more realistic phonological coding scheme, and explored a broader range of parameters than Rumelhart and McClelland's model, their results are farther from psychological reality. It is unknown whether any connectionist model can mimic a child's performance without resorting to unrealistic exogenous changes in the training or input, but it is clear that adding a hidden-layer and back-propagation does not ensure a solution. (shrink)

The Objective Threshold/Strategic Model proposes that strong, qualitative inferences of unconscious perception can be made if the relationship between perceptual sensitivity and stimulus visibility is nonlinear and nonmonotonic. The model proposes a nadir in priming effects at the objective identification threshold . These predictions were tested with masked semantic priming and repetition priming of a lexical decision task. The visibility of the prime stimuli was systematically varied above and below the objective identification threshold. The obtained relationship between prime visibility and (...) priming facilitation was nonlinear, but the results failed to confirm a nadir in priming effects at the objective identification threshold. We conclude that the objective identification threshold does not necessarily indicate the point where presumably unconscious priming effects might be inhibited by conscious cognitive processes. (shrink)

Three essays discuss aspects of Nietzsche's Thus Spake Zarathustra: the place of giftgiving in the portrayed economy, the meaning of feasting and parasitism, and references to the classical myth of Alcyone.

Descartes boldly claimed: "I think, therefore I am." But one might well ask: Why do we think? How? When and why did our human ancestors develop language and culture? In other words, what makes the human mind human? _Evolution of Mind, Brain, and Culture_ offers a comprehensive and scientific investigation of these perennial questions. Fourteen essays bring together the work of archaeologists, cultural and physical anthropologists, psychologists, philosophers, geneticists, a neuroscientist, and an environmental scientist to explore the evolution of the (...) human mind, the brain, and the human capacity for culture. The volume represents and critically engages major theoretical approaches, including Donald's stage theory, Mithen's cathedral model, Tomasello's joint intentionality, and Boyd and Richerson's modeling of the evolution of culture in relation to climate change. The volume contains chapters by: Peter Carruthers; Thierry Chaminade; Philip Chase; Merlin Donald; Peter Gardenfors; Gary Hatfield; Jody Hey; Steven Mithen; April Nowell; Peter Richerson and Robert Boyd; Theodore Schurr; Robert Seyfarth and Dorothy Cheney; Kim Sterelny; and Felix Warneken. ISBN 978-1-934536-49-0. (shrink)

This paper examines several contemporary readings of Piaget's texts: M. Chapman's Constructive Evolution provides a wide-ranging exegesis of Piaget's entire body of work; F. Vidal's Piaget before Piaget focuses on Piaget's earliest writings; and H. Beilin's Piaget's New Theory concentrates on Piaget's very last projects. All three contend that in contrast to accepted versions of Piaget's theory, there is a relatively unknown Piaget and a markedly differently way to understand Genetic Epistemology. This brief review attempts to bracket such readings within (...) the purview of postmodern concerns with rationality. 2012 APA, all rights reserved). (shrink)

Zubiri presents a critique of modernism and return to phenomena in primordial apprehension. Only 'notes' are apprehended; as real they need to be repossessed by logos or reason, related to other notes in the field or unified as the world. Zubiri seeks to overcome the dualism of sensing and knowing and introducing transcendent objects. His target extends to ancient and medieval philosophy, charged with introducing the problem. So he reads Plato's Sophist as positing being, known independent of the senses, and (...) the genera, derived deductively from being. This misreads Plato, reducing him to Parmenides. Rereading Plato, using Zubiri's scheme, reveals 'primordial apprehension' in the Theaetetus, with logos and reason in the Sophist. Like Zubiri, Plato's goal is to reconnect language and reality as apprehended. Unlike Zubiri, Plato sees communication as human dialogue, not just a feature of apprehended 'notes.' /// A apreensão primordial de Zubiri constitui uma crítica posmoderna e um retorno ao fenómeno. Segundo ele, o que se apreende são apenas 'notas'; estas, porém, exigem ser reassumidas pelo logos ou pela razão, encontrando-se sempre em relação com outras no campo que lhes é próprio ou unificadas enquanto mundo. Zubiri pretende sobretudo superar o dualismo entre sentimento e inteligência associado com a introdução de objectos transcendentais. A sua crítica extende-se à filosofia antiga e medieval, pois que, segundo ele, aqui se iniciou esta problemática da transcendentali-dade. Zubiri lê o Sofista precisamente como se Platão procedesse aqui a uma afirmação do ser, conhecido independentemente dos sentidos, e dos géneros, dedutivamente derivados do ser. O artigo pretende mostrar ser esta uma falsa interpretação de Platão, reduzindo-o a Parménides e, por isso, sugere uma releitura de Platão, baseada num esquema zubiriano, de modo a se poder discernir seja a noção de "apreensão primordial" no Teeteto ou de logos e razão no Sofista. Finalmente, mostra ainda como, tal como Zubiri, a meta de Platão está no estabelecimento de uma conexão entre a linguagem e a realidade apreendida. Ao mesmo tempo, porém, mostra como, ao contrário de Zubiri, a comunicação em Platão é vista como um verdadeiro diálogo humano e não apenas como aspecto de uma simples 'nota.'. (shrink)

Notice that I’m not saying that observations we in fact have made are not relevant to our beliefs about what exists. But the mere fact that something is observable does not give us any reason to think that it ever has or will in fact be observed. The issue between us is whether mere observability—as distinct from actual observation—is relevant to our beliefs about what exists. I submit that it is not.

Proposals for an ethical code for scientists raise questions about the usefulness of the framework of professional ethics for debating relevant issues surrounding ethics and science. Is science a profession and if so should its professional ethic be self-derived or subject to external input? What needs to be addressed is the nature of the 'good' that science promotes. Explanations of science as a public good in terms of knowledge and diversity are possibilities, but science's answer to the basic philosophical question (...) of hope in the human condition should not be overlooked. (shrink)

The possibilities of genetic engineering, particularly as applied to human beings, have provoked considerable debate for over two decades, but more recently the focus of public concern, at least, has turned to genetically modified food. Food has occasionally caught the attention of philosophers and bioethicists but is now ripe for further attention in the light of the implications of GM for policy in health, economics and politics. Macer has identified opposing reactions to novel foods—to prefer to eat down the food (...) chain, on the one hand, and to embrace technology, on the other. One question that has given rise to some interest is why consumer attitudes to genetically modified food have been so much more strongly adverse in Europe, particularly in the UK, than in the USA. This paper explores the ways in which the food ethics debate has been constructed in recent debates in the UK, with special reference to the similarities to and differences from what are on the face of it analogous debates in medical ethics. What is special about food, as opposed to drugs, which makes it appropriate or inappropriate to construct the arguments in the terms that currently predominate? This will involve looking in particular at the application of the principle of autonomy and the argument from consumer choice. (shrink)

Issues in genetics and genomics have been centre stage in Bioethics for much of its history, and have given rise to both negative and positive imagined futures. Ten years after the completion of the Human Genome Project, it is a good time to assess developments. The promise of whole genome sequencing of individuals requires reflection on personalization, genetic determinism, and privacy.

Pickering & Garrod (P&G) consider the possibility that inner speech might be a product of forward production models. Here I consider the idea of inner speech as a forward model in light of empirical work from the past few decades, concluding that, while forward models could contribute to it, inner speech nonetheless requires activity from the implementers.

...une tradition à la fois antique et directe, ininterrompue, orale, deformée, méconnaissable et vivante.M. ProustThis is a deliberately provocative title, chosen in an iconoclastic moment, when I was annoyed by reading yet another book, in which the author prostrates himself abjectly before the altar of Homer the historian. The worship of this false god has reached such proportions that every writer on Mycenaean Greece devotes a great deal of space to what Homer says, and spends page after page trying to (...) reconcile the Homeric account with the archaeological evidence. The idea that Homer can tell us about the Mycenaean Age dies hard; it is time to administer the coup de grâce. (shrink)

Issues arising in connection with genes and nutrition policy include both nutrigenomics and nutrigenetics. Nutrigenomics considers the relationship between specifc nutrients or diet and gene expression and, it is envisaged, will facilitate prevention of diet-related common diseases. Nutrigenetics is concerned with the effects of individual genetic variation on response to diet, and in the longer term may lead to personalised dietary recommendations. It is important also to consider the surrounding context of other issues such as novel and functional foods in (...) so far as they are related to genetic modification. Ethical issues fall into a number of categories: why nutrigenomics? Will it have important public health benefits? questions about research, e.g. concerning the acquisition of information about individual genetic variation; questions about who has access to this information, and its possible misuse; the applications of this information in terms of public health policy, and the negotiation of the potential tension between the interests of the individual in relation to, for example, prevention of conditions such as obesity and allergy; the appropriate ethical approach to the issues, e.g. the moral difference, if any, between therapy and enhancement in relation to individualised diets; whether the 'technological fix' is always appropriate, especially in the wider context of the purported lack of public confidence in science, which has special resonance in the sphere of nutrition. (shrink)

Interactive theories of lexical retrieval in language production assume that activation cascades from earlier to later processing levels, and feeds back in the reverse direction. This commentary invites Pickering & Garrod (P&G) to consider whether cascading and feedback can be seen as a form of forwarding modeling within a hierarchical production system.