The ability to effectively prevent smallpox was the greatest medical accomplishment of the first half of the 19th century. From 1838 to 1840, half a century after vaccination was introduced but before it became mandatory in England, data about the general population of England and Wales recorded 70 deaths per million from smallpox; only 180, 900 vaccinations were recorded. In London alone from 1848 to 1852, there were 4, 858 youthful deaths from smallpox, 67% of which occurred during the first (...) five years of life (Simon 1857).In a report to the House of Commons in 1802, Edward Jenner (1749-1823) stated that person-to-person vaccination was a basic principle of his procedure. He gained confidence in it from the case .. (shrink)

As etiologic concepts of diseases gradually changed from humoral to microbial in the 19th century, syphilis presented particularly great challenges to doctors and scientists. Was “syphilis” merely a synonym for “venereal disease,” and did all manifestations attributed to it have the same cause? The discovery in 1879 of the gonococcus by Albert L. Neisser , and of the cause of chancroid, or soft chancre, in 1890 by Augusto Ducrey , established that venereal disease and syphilis were not synonymous, but syphilis (...) continued to mystify investigators. Symptoms could disappear for years and then—in most but not all persons—reappear with entirely different “tertiary” manifestations. .. (shrink)

The Irish poet W. B. Yeats once wrote, with great sapience and perception: Nor dread, nor hope attend A dying animal; A man awaits his end Dreading and hoping all. That death has ever been a problem to man is attested as far back as we can trace our species in the archaeological record—indeed, it seems to have been a problem even for that immediate precursor of homo sapiens, the so-called Neanderthal Man; for he buried his dead.

The aim of this article is to offer what I consider to be necessary substantiati for the view that the description of the walk which acts as a frame for the singing contest in Id. 7 is based on a precise knowledge of the geography of t island of Cos and that the poem thus displays a topographical realism unique Greek pastoral.

G Reddiford; Sociology, Psychology and the Study of Education, Journal of Philosophy of Education, Volume 3, Issue 1, 30 May 2006, Pages 81–103, https://doi.org.

The state-of-art research in the field of life’s organization confronts the need to investigate a number of interacting components, their properties and conditions of sustainable behaviour within a natural system. In biology, ecology and life sciences, the performance of such stable system is usually related to homeostasis, a property of the system to actively regulate its state within a certain allowable limits. In our previous work, we proposed a deterministic model for systems’ homeostasis. The model was based on dynamical system’s (...) theory and pairwise relationships of competition, amensalism and antagonism taken from theoretical biology and ecology. However, the present paper proposes a different dimension to our previous results based on the same model. In this paper, we introduce the influence of inter-component relationships in a system, wherein the impact is characterized by direction (neutral, positive, or negative) as well as its (absolute) value, or strength. This makes the model stochastic which, in our opinion, is more consistent with real-world elements affected by various random factors. The case study includes two examples from areas of hydrobiology and medicine. The models acquired for these cases enabled us to propose a convincing explanation for corresponding phenomena identified by different types of natural systems. (shrink)

What Is a Person: Untapped Insights from Africa, a new book by Nancy Jecker and Caesar Atuire, offers an appealing and fresh perspective into ongoing debates surrounding personhood.1 The bioethics literature has, largely, drawn from Western/global North thought or (as arguably with the case of principlism) amalgamations of those traditions.2 3 This leaves substantial room for enriching current debates through insights from and engagement with understudied traditions. Just such an approach is taken by Jecker and Atuire, who in particular bring (...) African philosophical theories of personhood into dialogue with Western ones. Their critical appraisal ably identifies flaws with a range of theories across different traditions, and their book attempts to put forward a new theory of personhood that aims to draw from the best and discard the worst of those theories: Emergent Personhood. The book’s early sections indeed are very useful in terms of critical comparative analysis, resulting in insights such as the finding that both traditional African and traditional Western (or more specifically, Greco-Roman) thought actually overlap in terms of how personhood is conceptualised: extrinsic, earned, scalar and changing. Modern Western thought, though, eschewed those concepts first through the introduction of Christian moral equality, then Enlightenment systematic secular theories like deontology and utilitarianism that claim non-theological basis for such moral personhood. By contrast, the contemporary African theories Jecker and Atuire cite largely align with the traditional, relational accounts. So does their theory of Emergent Personhood succeed where African and Western thought have fallen short? While the theory’s contours are promising, several aspects are in need of further development. In this brief commentary, I will highlight three somewhat inter-related issues: (1) The criteria by which theories of personhood are evaluated are never given firm normative justification; (2) The normative force of Emergent Personhood’s relational foundations are not explicated; …. (shrink)