A reductionistic, bottom‐up, cellular‐based concept of the origins of sentience and consciousness has been put forward. Because all life is based on cells, any evolutionary theory of the emergence of sentience and consciousness must be grounded in mechanisms that take place in prokaryotes, the simplest unicellular species. It has been posited that subjective awareness is a fundamental property of cellular life. It emerges as an inherent feature of, and contemporaneously with, the very first life‐forms. All other varieties of mentation are (...) the result of evolutionary mechanisms based on this singular event. Therefore, all forms of sentience and consciousness evolve from this original instantiation in prokaryotes. It has also been identified that three cellular structures and mechanisms that likely play critical roles here are excitable membranes, oscillating cytoskeletal polymers, and structurally flexible proteins. Finally, basic biophysical principles are proposed to guide those processes that underly the emergence of supracellular sentience from cellular sentience in multicellular organisms. (shrink)

The presented paper proposes a state machine of REA (Resource–Event–Agent) model. This model constitutes a fundamental building block for value modeling applications. Contrary to other appr...

The paper deals with the state of the social sciences after the boom of internet services in the Czech Republic in the 1990s. The results of our survey, based on 512 responses from the economics and history departments of major Czech public universities, show that internet services are considered a quality factor for academic output; however, the issues of plagiarism, a lack of resource criticism, inadequacy of impact factor-based evaluations, poor academic training for the new generation of social scientists, the (...) failure of state academic policy, and the generation gap make further development in the Czech social sciences rather problematic. As a result we recommend creating a better communication link between policy makers and scholars, reforming the current state policy which encourages lower quality academic output, and improving academic training, which requires a more individual approach, and also placing higher demands on social scientists. (shrink)

Předložená práce je textově filosofickou analýzou první části Platónova dialogu Menón, přičemž se snaží předvést, jak v konkrétním literárním díle Platónově je obsažen střet mezi silou již skomírajícího světa tradice (s jejími hodnotami lidského života), a silou jedince, který hodnoty lidského života sám pro sebe vydobyl v kritické diskusi s tradicí. Všechny tři pokusy definovat co je vlastně areté, odhalují při pečlivém rozboru pouhé rétorické střetnutí Menóna se Sókratem jako příklad střetu dvou odlišných paradigmat a sil, uvedených výše.

Book review: Aristotelés, Etika Eudémova, Praha (Dybbuk), transl. Viktor Zavřel – Jan Brázdil, 2020, 168 p.

Cellular circadian clocks represent ancient anticipatory systems which co‐evolved with the first cells to safeguard their survival. Cyanobacteria represent one of the most ancient cells, having essentially invented photosynthesis together with redox‐based cellular circadian clocks some 2.7 billion years ago. Bioelectricity phenomena, based on redox homeostasis associated electron transfers in membranes and within protein complexes inserted in excitable membranes, play important roles, not only in the cellular circadian clocks and in anesthetics‐sensitive cellular sentience (awareness of environment), but also in the (...) coupling of single cells into tissues and organs of unitary multicellular organisms. This integration of cellular circadian clocks with cellular basis of sentience is an essential feature of the cognitive CBC‐Clock basis of cellular life. (shrink)

A review of Lubomír Doležel´s Possible Worlds of Fiction and History: The Postmodern Stage (Baltimore: Johns Hopkins University Press, 2010, 171 pp. ISBN 978-0-8018-9463-3).

The similarity between logic and semantics of the Stoics and Frege has long been known, and it can be explained in various ways. In 2021, Susane Bobzien published a work in which she explains this similarity rather surprisingly: she hypothesizes that Frege generously helped himself with the foundations of Stoic logic as it was published in the first volume of History of Logic in the West by Carl Prantl. However, this hypothesis encounters various problems. The key point of the whole (...) accusation is founded on the formulation of a general propo-sition in language using implication and anaphora, which Frege supposedly took from the Stoics, although in Prantl’s text there is only one example of a sentence with this structure. On the contrary, there are many examples of such sentences in contemporary professional (e.g. legal) texts. Many examples of semantic simi-larities that Bobzien presents are based only on the similarities between isolated concepts; however, that is regularly the case for such concepts with the same conceptual basis. Bobzien presents a significant number of matches only on the basis of results that could allegedly be inferred from the texts. However, this cannot be considered a proof of plagiarism. Bobzien does not consider many sources for the continuity of interpretation such as the so-called hypothetical syllogism found in available textbooks of logic. Last but not least, her claims do not consider many differences between Stoic and Frege’s logic. All this leads us to the conclusion that Bobzien does not present sufficient facts and connections between them that would confirm her hypothesis about Frege’s plagiarism of the Stoic logic: Frege simply was not a plagiarist. (shrink)

Úspěšná kniha MUDr. Františka Koukolíka Mocenská posedlost se vrací na knižní trh v novém vydání, od základu přepracovaná a doplněná bohatou věcnou dokumentací. Fenomén moci od prvního vydání knihy (Karolinum 2011) zdá se posílil a více prorostl mnoha, prakticky všemi oblastmi života populace na planetě Zemi. Nové zpracování problému se opírá o čísla statistik, o interpretaci každodenních událostí ve světě, o výsledky anket a psychologických experimentů, nepomíjí ani autorovu doménu – neurovědu jako zdroj poznání nejniternějších lidských podnětů i úchylek. Metodou (...) pohledu je ovšem vždy kritický rozum. Skrze něj a v širokých souvislostech podává autor obraz světa, který je stále více varující. (shrink)

[An important attempt to explain the development of civilized humanity].

Oceanic languages typically make a grammatical contrast between expres- sions of alienable and inalienable possession. Moreover, further distinctions are made in the alienable category but not in the inalienable category. The present research tests the hypothesis that there is a good motivation for such a development in the former case. As English does not have a grammaticalized distinction between alienable and inalienable possession, it provides a good testing ground. Three studies were conducted. In Study 1, participants were asked to write (...) down the first interpretation that came to mind for possessive phrases, some of which contained inherently relational possessums, while o thers contained possessums that are not inherently relational. Phrases with non-relational possessums elicited a broader range of interpretations and a lower consistency of a given interpretation across possessor modifiers than those with relational possessums. Study 2 demonstrated that users assign a default interpretation to a possessive phrase containing a relational possessum even when another reading is plausible. Study 3, a corpus-based analysis of possessive phrase use, showed that phrases with relational possessums have a narrower range of interpretations than those with other possessums. Taken together, the findings strongly suggest that grammatical distinctions between different types of alienable possession are motivated. (shrink)

Polarity is an inherent feature of almost all prokaryotic and eukaryotic cells. In most eukaryotic cells, growth polarity is due to the assembly of actin‐based growing domains at particular locations on the cell periphery. A contrasting scenario is that growth polarity results from the establishment of non‐growing domains, which are actively maintained at opposite end‐poles of the cell. This latter mode of growth is common in rod‐shaped bacteria and, surprisingly, also in the majority of plant cells, which elongate along the (...) apical–basal axes of plant organs. The available data indicate that the non‐growing end‐pole domains of plant cells are sites of intense endocytosis and recycling. These actin‐enriched end‐poles serve also as signaling platforms, allowing bidirectional exchange of diverse signals along the supracellular domains of longitudinal cell files. It is proposed that these actively remodeled end‐poles of elongating plant cells remotely resemble neuronal synapses. BioEssays 25:569–576, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

Táto štúdia ponúka stručné uvedenie do sokratovskej otázky, pričom sa v nej kladie dôraz predovšetkým na Platónovho Sókrata. Prvá časť príspevku sleduje vznik sókratovskej otázky v antike. V druhej časti sa pojednáva o vzostupe Platónovej autority v riešení tejto otázky. Nasledujúca časť podáva argumenty, prečo je Platónov portrét Sókrata z pohľadu historika filozofie neudržateľný a nedôveryhodný. Navrhované riešenia sókratovského problému spočívajú v zdržaní sa úsudku o historickej autentickosti Platónovho Sókrata.

Considerations related to randomness appear relatively late in European history, at the turn of the Middle Ages and the modern era. They initially concern to the chances of winning in various games or situations and later move on to introduce classical and geometric probabilities. From a mathematical point of view, the probability calculus is completed by Kolmogorov’s axiomatic theory. However, many open questions, problems and paradoxes remain in the way probability is perceived and interpreted. The four main directions in the (...) concept of probability (logical, frequentist, subjective and propensity) are closely related to the way of perceiving randomness (epistemological or ontological). Reflections on the evolution of the perception of randomness and the interpretation of probability bring the ability to navigate the basic principles and findings of science and contributes to a deeper understanding of the entire issue. (shrink)