The secondary vascular tissues (xylem and phloem) of woody plants originate from a vascular cambium and develop as radially oriented files of cells. The secondary phloem is composed of three or four cell types, which are organised into characteristic recurrent cellular sequences within the radial cell files of this tissue. There is a gradient of auxin (indole acetic acid) across both the cambium and the immediately postmitotic cells within the xylem and phloem domains, and it is believed that this morphogen, (...) probably in concert with other morphogenic factors, is closely associated with the determination and differentiation of the different cells types in each tissue. A hypothesis is developed that, in conjunction with the positional values conferred by the graded radial distribution of morphogen, cell divisions at particular positions within the cambium are sufficient to determine not only each of the phloem cell types but also their recurrent pattern of differentiation within each radial cell file. BioEssays 27: 533–541, 2005. © 2005 Wiley periodicals, Inc. (shrink)

The levels that compose biological hierarchies each have their own energetic, spatial and temporal structure. Indeed, it is the discontinuity in energy relationships between levels, as well as the similarity of sub-systems that support them, that permits levels to be defined. In this paper, the temporal structure of living hierarchies, in particular that pertaining to Human society, is examined. Consideration is given to the period defining the lifespan of entities at each level and to a periodic event considered fundamental to (...) the maintenance of that level. The ratio between the duration of these two periods is found to be approximately 2.5 × 104. A similar relationship is found when lower, non-living levels of molecules and atoms are considered. This suggests that there is a constant factor of amplification between analogous periodic events at successive levels of the Human hierarchy. (shrink)

There is a certain measure of perplexity concerning the significance of endopolyploidy. It seems that this results from a narrow frame of reference from which investigators view the phenomenon; that is, a predilection for emphasizing the specialized functional aspect of endopolyploidy as it operates in species at the present time overrides any consideration of the rôle that this state may play in the life of a species in its encounter with the forces of natural selection either in the past or (...) in the future.There does not seem to be any obvious relationship between the degree of endopolyploidy that a species can exhibit and either its basic DNA content or the structure of its nucleus. The significance of endopolyploidy may reside not so much in any specialized function that the condition can support, but rather in the properties that are consequent upon the endopolyploid condition itself and which are distinct from those that apply to diploid cells. Some of the properties of the endopolyploid state, and examples of their manifestation in plants and animals, are discussed. The conclusion is that these properties have a potential that opens possibilities for new paths of development and serves as a factor upon which natural selection can operate. (shrink)

Polarity is an inherent feature of almost all prokaryotic and eukaryotic cells. In most eukaryotic cells, growth polarity is due to the assembly of actin‐based growing domains at particular locations on the cell periphery. A contrasting scenario is that growth polarity results from the establishment of non‐growing domains, which are actively maintained at opposite end‐poles of the cell. This latter mode of growth is common in rod‐shaped bacteria and, surprisingly, also in the majority of plant cells, which elongate along the (...) apical–basal axes of plant organs. The available data indicate that the non‐growing end‐pole domains of plant cells are sites of intense endocytosis and recycling. These actin‐enriched end‐poles serve also as signaling platforms, allowing bidirectional exchange of diverse signals along the supracellular domains of longitudinal cell files. It is proposed that these actively remodeled end‐poles of elongating plant cells remotely resemble neuronal synapses. BioEssays 25:569–576, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

Shepard promotes the important view that evolution constructs cognitive mechanisms that work with internalized aspects of the structure of their environment. But what can this internalization mean? We contrast three views: Shepard's mirrors reflecting the world, Brunswik's lens inferring the world, and Simon 's scissors exploiting the world. We argue that Simon 's scissors metaphor is more appropriate for higher-order cognitive mechanisms and ask how far it can also be applied to perceptual tasks. [Barlow; Kubovy & Epstein; Shepard].

We appreciate Meynen’s examination of ethical implications of using neurotechnologies to decode neural data and make inferences about cognitive processes. Here, we address three issues that we beli...

Kant's Critique of Teleological Judgment is read as a reflection on philosophical methodological problems that arose through the constitution of an independent science of life - biology. This work presents an example of the interconnections between philosophy and the history of science.

Plausibly, when we adopt a probabilistic standpoint any measure Cb of the degree to which evidence e confirms hypothesis h relative to background knowledge b should meet these five desiderata: Cb > 0 when P > P < 0 when P < P; Cb = 0 when P = P. Cb is some function of the values P and P assume on the at most sixteen truth-functional combinations of e and h. If P < P and P = P then (...) Cb ≤ Cb; if P = P and P < P then Cb ≥ Cb. Cb – Cb is fully determined by Cb and Cbe – Cbe; if Cb = 0 then Cb + Cbe = 0. If P = P then Cb = Cb. (shrink)

I "argue" that by knowingly accepting a set of propositions which is logically inconsistent, An epistemic agent need not violate any valid epistemic rule. Those types of logically inconsistent sets which it is permissible to accept are distinguished from those which may not be accepted. The results of the discussion are applied to the lottery paradox set of propositions and the preface paradox set. I also "suggest" that it may be an epistemic virtue to accept some inconsistent sets.

The emergence of experimental philosophy was one of the most significant developments in the early modern period. However, it is often overlooked in modern scholarship, despite being associated with leading figures such as Francis Bacon, Robert Boyle, Isaac Newton, Jean Le Rond d'Alembert, David Hume and Christian Wolff. Ranging from the early Royal Society of London in the seventeenth century to the uptake of experimental philosophy in Paris and Berlin in the eighteenth, this book provides new terms of reference for (...) understanding early modern philosophy and science, and its eventual eclipse in the shadow of post-Kantian notions of empiricism and rationalism. Experimental Philosophy and the Origins of Empiricism is an integrated history of early modern experimental philosophy which challenges the rationalism and empiricism historiography that has dominated Anglophone history of philosophy for more than a century. (shrink)

The reconciliation of theories of concepts based on prototypes, exemplars, and theory-like structures is a longstanding problem in cognitive science. In response to this problem, researchers have recently tended to adopt either hybrid theories that combine various kinds of representational structure, or eliminative theories that replace concepts with a more finely grained taxonomy of mental representations. In this paper, we describe an alternative approach involving a single class of mental representations called “semantic pointers.” Semantic pointers are symbol-like representations that result (...) from the compression and recursive binding of perceptual, lexical, and motor representations, effectively integrating traditional connectionist and symbolic approaches. We present a computational model using semantic pointers that replicates experimental data from categorization studies involving each prior paradigm. We argue that a framework involving semantic pointers can provide a unified account of conceptual phenomena, and we compare our framework to existing alternatives in accounting for the scope, content, recursive combination, and neural implementation of concepts. (shrink)

We are thankful for the opportunity to reflect more on the difficult problem of the relationship between moral evaluations and the construct of personality disorders in response to the commentaries by Mike Martin and Louis Charland. We begin by emphasizing to readers that this important problem is complicated by the different perspectives of the various disciplines involved, especially, philosophy, psychiatry, and psychology. Incredulity, anger, and dismay are among the reactions we encountered in discussions of these issues, especially with some mental (...) health professionals. Strong reactions on either side of a disciplinary divide occasionally present barriers to a dispassionate discussion of the topic. .. (shrink)

"This book is an augmented and updated translation by the author of Theorie des Subjekts: Subjectiviteat und Identiteat zwischen Moderne und Postmoderne, Teubingen, Francke-UTB, 2010 (3rd ed.)"--Title page verso.

We examined Confucian moral philosophy, primarily the Analects, to determine how Confucian ethics could help managers regulate their own behavior (self-regulation) to maintain an ethical standard of practice. We found that some Confucian virtues relevant to self-regulation are common to Western concepts of management ethics such as benevolence, righteousness, wisdom, and trustworthiness. Some are relatively unique, such as ritual propriety and filial piety. We identify seven Confucian principles and discuss how they apply to achieving ethical self-regulation in management. In addition, (...) we examined some of the unique Confucian practices to achieve self-regulation including ritual and music. We balanced the framework by exploring the potential problems in applying Confucian principles to develop ethical self-regulation including whistle blowing. Confucian moral philosophy offers an indigenous Chinese theoretical framework for developing ethical self-regulation in managers. This is relevant for managers and those who relate to managers in Confucian-oriented societies, such as China, Korea, Japan, and Singapore. We recommend further research to examine if the application of the Confucian practices outlined here actually work in regulating the ethical behavior of managers in modern organizations. (shrink)

Recently, a number of philosophers of science have claimed that much explanation in the sciences, especially in the biomedical and social sciences, is mechanistic explanation. I argue the account of mechanistic explanation provided in this tradition has not been entirely satisfactory, as it has neglected to describe in complete detail the crucial causal structure of mechanistic explanation. I show how the interventionist approach to causation, especially within a structural equations framework, provides a simple and elegant account of the causal structure (...) of mechanisms. This account explains the many useful insights of traditional accounts of mechanism, such as Carl Craver's account in his book Explaining the Brain , but also helps to correct the omissions of such accounts. One of these omissions is the failure to provide an explicit formulation of a modularity constraint that plays a significant role in mechanistic explanation. One virtue of the interventionist/structural equations framework is that it allows for a simple formulation of a modularity constraint on mechanistic explanation. I illustrate the role of this constraint in the last section of the paper, which describes the form that mechanistic explanation takes in the computational, information-processing paradigm of cognitive psychology. (shrink)

Appraisal theories of emotions have gained widespread acceptance in the field of emotion research (for a recent overview, see, e.g., Scherer, Schorr, & Johnstone, 2001). In these theories, it is as...

Desire-based accounts of practical argument about incompatible ends seem limited either to advice about means or to coercive threats. This paper argues that this can be avoided if the parties to the dispute desire its resolution by means other than force more than they desire the satisfaction of any particular ends. In effect, this means they must argue as if in a position of equal power. This leads to an explanation of the apparent objectivity of moral claims and of why (...) moral reasons appear to be categorical and external. It also explains how notions such as reciprocal altruism and TIT-FOR-TAT can play a role in an evolutionary account of morality. The paper concludes with an argument to the effect that a desire-based metaethic must accept the is-ought gap and explains why there may appear to be no is-ought gap from within a given normative perspective. (shrink)

This title is written to match GCSE Religious Studies AQA B, option 2 and can be used as part of a full course or short course. It contains summaries and practise exam questions at the end of each section to help prepare for exams.

In this brief commentary, I would like to discuss two reservations I have about the article by Bergner and Bunford. Before doing so let me make some preliminary remarks.Their hypothesis that the concept of disability unites the various mental disorder constructs that have been proposed over the centuries and across cultures is reasonable and accords well with common sense. The concept of disability does a lot of good work in helping us to understand mental disorders.With respect to the authors’ contrast (...) between the disability conception versus the behavioral conception of mental disorder, the notion that counting behaviors alone justifies diagnosing a psychiatric disorder is worth critiquing. Claiming that everyone... (shrink)

The Contrast Between the nomothetic versus the idiographic was popularized in psychology by Gordon Allport (1937). In the early 1930s, Allport made his name by advocating for a quantitative, trait-based approach to the study of personality in contrast with the prevailing case study approach. In doing so, he was following the trend toward greater reliance on measurement in psychology as a whole. Allport, however, had grave doubts about the sufficiency of quantitative measurement for developing an understanding of individual psychological functioning. (...) The nomothetic versus the idiographic was meant to give voice to these doubts.1 For Allport, the nomothetic referred to the study of populations with the aim .. (shrink)

It is generally agreed that the argument about Achilles and the tortoise was intended to prove that the concept of movement was contradictory or ambiguous and therefore that it did not belong in the foundations of ontology. It is suggested here that the argument stands unless we are prepared to define a standard time by means of dynamical concepts. It would be a premature assumption, however, to suppose that Zeno himself should have been so prepared.

Problems arising from the transformation of Hungary from a monolithic society into a market economy are addressed. In the past, under communism, the worker was a faceless digit in a mass proletariat. He had no rights, but also no sense of obligation to society and the community. How can the business community instil in its worker a sense of their own unique individuality and role in their company and in society, a psychological awakening that will benefit not only the works (...) himself but his employer and the company's end product? This new corporate culture must trickle down from the management who must undertake the task of re?educating their workers in the interests of improved production and a better society. The author calls this the Molecule Maxim, in that management must stop thinking from the top downwards and start at the bottom of the pyramid, radiating outwards and upwards from this infinitesimal particle?the molecule?around which to build the concept, aim the creativity and thus the ultimate success and profitability of the company. (shrink)

Nathan Salmon has defended what might be called “weak modal anti-realism”—the view that possible-object names can refer to possible objects that neither exist nor are otherwise real. But rather than adopting a similar view in the fictional case, he instead defends fictional creationism—the view that fictional characters are existent but abstract entities created by authors of fiction. In this paper, I first argue that if weak modal antirealism is defensible then weak fictional antirealism is defensible as well. Second, I argue (...) that there is no reason to prefer fictional creationism over weak fictional antirealism but there is very good reason to prefer the latter over the former. And third, I defend weak fictional antirealism against the charge that it cannot provide a satisfactory account of statements that prima facie involve reference to or quantification over fictional characters. (shrink)

I explore a strand of reception history that follows Rudolf Carnap’s shift from a purely syntactical analysis of constructed languages to his conception of pure semantics. My exploration focuses on Gustav Bergmann’s and Everett Hall’s interpretation of pure semantics, their understanding of what constitutes a ’formal’ investigation of language, and their arguments concerning the relationship between expressions and their extra-linguistic referents. I argue that Bergmann and Hall strongly misread Carnap’s semantic project and, subsequently, their misunderstanding is passed down through colleagues (...) and students. (shrink)

The central concern of this paper is the nature of the relation between words on the one hand and their occurrences on the other. I argue here that while Kaplan's “common currency” conception of words is immune to much of the criticism to which Cappelen has subjected it, it runs afoul of the role words play in communication. And I sketch an alternative conception – the type‐continuant model – which shares the virtues but avoids the vices of Kaplan's conception.

This volume presents new work in history and historiography to the increasingly broad audience for studies of the history and philosophy of science. These essays are linked by a concern to understand the context of early modern science in its own context.