This article offers a definition of microaggressions that picks out a distinct injustice, and defines the injustice in question as structural. The article also argues that to be a relational egalitarian requires considering our social norms and social practices: the kinds of things that produce microaggressions and so structure socially unequal relations.

Abstract‘The Future of Legal Gender’ project has assessed the potential implications for feminist legal scholarship and activism of decertifying sex/gender. Decertification refers to the state moving away from officially determining or registering sex/gender. This article explores the potential impact of such moves on equal pay law and gender pay gap reporting. Equal pay and gender pay gap reporting laws provide an important focus for the project because they aim to address structural dynamics associated with persistent pay inequality that women experience (...) across occupations in the United Kingdom. These legal measures illuminate gendering as a large-scale social problem widely understood to operate structurally and systemically. What effect, then, could decertifying sex/gender have on the law and conceptual power of equal pay? Might decertification undermine the structure of equal pay law, with all hard-won gains it has brought for women? Or is it possible to imagine that decertification could accompany a more inclusive and effective legal architecture for equal pay? (shrink)

This book draws its inspiration from Hilbert, Wittgenstein, Cavaillès and Lakatos and is designed to reconfigure contemporary philosophy of mathematics by making the growth of knowledge rather than its foundations central to the study of mathematical rationality, and by analyzing the notion of growth in historical as well as logical terms. Not a mere compendium of opinions, it is organised in dialogical forms, with each philosophical thesis answered by one or more historical case studies designed to support, complicate or question (...) it. The first part of the book examines the role of scientific theory and empirical fact in the growth of mathematical knowledge. The second examines the role of abstraction, analysis and axiomatization. The third raises the question of whether the growth of mathematical knowledge constitutes progress, and how progress may be understood. Readership: Students and scholars concerned with the history and philosophy of mathematics and the formal sciences. (shrink)

Canada’s Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans mandates that all research involving human subjects be reviewed and approved by a research ethics board . We have little evidence on how researchers are dealing with this requirement in multisite studies, which involve more than one REB. We retrospectively examined 22 REB submissions for two minimal-risk, multisite studies in leading Canadian institutions. Most REBs granted expedited review to the studies, while one declared the application to be exempt from review. (...) Time between submission and approval ranged greatly, from four to 546 days. We received a total of 155 REB queries for changes and clarifications, most of which asked for further information, clarification, or additional documents. Less than a third of the REB queries were requests for specific changes, and a vast majority had a very limited impact on the research projects. Institutions also varied broadly in their description of what was required of local principal investigators. We conclude that the organizational and practical challenges these results imply could deter researchers from embarking on multisite research projects, and that recently proposed changes to the TCPS will not solve these problems. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps, and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may (...) freely copy and distribute this work, as no entity has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Emerging demonstrations of the malleability of distance perception in affective situations require an organizing structure. These effects can be predicted by approach and avoidance orientation. Approach reduces perceptions of distance; avoidance exaggerates perceptions of distance. Moreover, hedonic valence, motivational intensity, and perceiver arousal cannot alone serve as organizing principles. Organizing the literature based on approach and avoidance can reconcile seeming inconsistent effects in the literature, and offers these motives as psychological mechanisms by which affective situations predict perceptions of distance. Moreover, (...) this perspective complements functional models of perception claiming perceptions of distance serve adaptive responding, and in so doing suggests why perceptions of distance respond to affective situations. This review contributes to the building of a broader theory of motivated distance perception. (shrink)

Article published in Progress in Human Geography, Aug 2017. This is a pre-publication version of the article ; please see early online version at publisher website for final version.: This article examines rhythmanalysis within the context of Henri Lefebvre's critique of everyday life and identifies gaps in his framework from the vantage point of intersectional feminist scholarship. Intersectional rhythmanalysis, I argue, provides a framework - Géographie – Nouvel article.

With the normative demand to attend to social difference and an absence of universal evaluative terms with which to do so, recent theory has increasingly turned to the study of the affective rather than epistemological conditions of ethical encounter. This I call a “dispositional ethics” that construes responsibility as responsiveness. Recent articulations of such an ethics, notably in the most current work of Judith Butler, James Tully, Jade Larissa Schiff, and Ella Myers, highlight its connection to situated practices of concrete (...) bodies-in-relation, but often stop short of developing an account of what such embodied practices might be. Based on interviews with thirteen experts who take the body as their primary vocational and intellectual field and characterize their practice as an art of listening, I distinguish three dimensions of a dispositional ethics in practice and some of the specific strategies available to cultivate the conditions for responsiveness in political life. (shrink)

In this article we report relevant data that shed light on the topic of hope and patients’ expectations in the use of DBS, for standard, approved, and established indications, based on a broader qualitative study on the ethical and social challenges that healthcare providers face in the field of DBS.

I assess various proposals for the source of the intuition that there is something problematic about contextuality, ultimately concluding that contextuality is best thought of in terms of fine-tuning. I then argue that as with other fine-tuning problems in quantum mechanics, this behaviour can be understood as a manifestation of teleological features of physics. Finally I discuss several formal mathematical frameworks that have been used to analyse contextuality and consider how their results should be interpreted by scientific realists. In the (...) course of this discussion I obtain several new mathematical results—I demonstrate that preparation contextuality is a form of fine-tuning, I show that measurement contextuality can be explained by appeal to a global constraint forbidding closed causal loops, and I demonstrate how negative probabilities can arise from a classical ontological model together with an epistemic restriction. (shrink)

The ‘new realist’ G E Moore is hardly known as a metaphysician of time, yet I argue his 1910–11 lectures, later published as Some Main Problems of Philosophy, offer the first substantial English-language defence of presentism and the A-theory. This paper contextualises Moore’s positions, stressing his intellectual connections with J M E McTaggart and Bertrand Russell; explores his Common Sense metaphysics of time; and argues that his time realism owes a great debt to ‘old realist’ Henry Sidgwick.

Most research on the corporate philanthropy of organizations has focused on the external benefits of such initiatives for firms, such as benefits for firm reputation and opportunities. However, many firms justify their giving, in part, due to the positive impact it has on their employees. Little is known about the effectiveness of such efforts, or how they can be managed strategically to maximize impact. We hypothesize a main effect of office-level corporate philanthropy on average employee attitudes in that office, but (...) also investigate three strategies that offices may use to enhance this impact. Testing our hypotheses with 3 years of data on attitudes of an average of 14,577 employees in 53 offices we find support for the main effect, but mixed support for the specific strategies used to enhance impact. (shrink)

Everyday ethics refers to those issues which have a sometimes unrecognized moral dimension and that arise regularly within healthcare and research. These issues are often contrasted to dramatic ethics issues (i.e. issues that have seemingly higher stakes such as those arising in acute care situations or with invasive or life-threatening interventions). Claims have been made that scholarly bioethics tends to focus on dramatic ethics to the detriment of everyday ethics discussions. However, empirical evidence showing this has been lacking. Our own (...) research investigating bioethics discussions in the Parkinson’s disease literature suggested this trend. Consequently, we decided to characterize the context and content of the Parkinson’s disease bioethics literature to empirically test the hypothesis that everyday ethics is under discussed. We conducted a broad literature search using the keywords “Parkinson’s disease” AND (“ethics” OR “bioethics”) and classified results inductively based on the context in which the bioethics discussion occurred. In line with our hypothesis and initial observations, we found that there is indeed a greater focus on dramatic ethics where topics such as deep brain stimulation and neuronal cell transplantations, dominated bioethics discussions. Given the potential utility of everyday ethics in improving healthcare and research, this mismatch in focus ought to be addressed. There is a clear need for further understanding and discussion of everyday ethical issues in scholarly bioethics. (shrink)

The concept of self-gaslighting has recently become prevalent in popular discourse but has yet to be subjected to detailed philosophical analysis. In this paper, I examine one context in which self-gaslighting is often discussed: situations in which someone has experienced trauma. I argue that the phenomenon currently described as self-gaslighting fails to display core features of manipulative gaslighting and that therefore we should seek other conceptual resources for understanding such cases. I suggest that self-gaslighting, at least in some paradigmatic cases, (...) amounts to either extremely successful interpersonal gaslighting or to internalized oppression. Utilizing these concepts instead of self-gaslighting avoids conceptual difficulties and also has a significant practical payoff. By moving away from the language of self-gaslighting we can move away from feelings of self-blame that so often accompany trauma. (shrink)

In the article “Nudging and Informed Consent”, Cohen argues that the use of “nudging” by physicians in the clinical encounter may be ethically warranted because it results in an informed consent where obligations for beneficence and respect for autonomy are both met. However, the author's overenthusiastic support for nudging and his quick dismissal of shared decision-making leads him to assume that “soft” manipulation is un-problematic and that “wisdom” on the side of medical professionals will suffice to guard against abuse. Opposing (...) this view, we propose that: 1) patient preferences and values should not be boiled down to rational or irrational decisions based on cognitive reasoning alone, 2) potential threats to the physician-patient must be mitigated and could be minimized by employing alternative strategies that acknowledge the impact of cognitive heuristics in shaping decision-making but maintain transparency and trust, and 3) patient preferences and values can be legitimately influenced only under specific circumstances. The latter include: (1) exhaustion of other means; (2) evidence that nudging is effective in a specific context; (3) evidence of clear and active public misinformation (e.g., industry promoting smoking); (4) explicit pubic dialogue between various stakeholders including medical professional societies about nudging; (5) upholding shared decision-making as a preferred approach; and (6) a rich understanding of clinical reality beyond the simple dichotomy of beneficence-autonomy. (shrink)

Recent work in the philosophy of emotion focuses on challenging dualistic conceptualizations. Three of the most obvious dualisms are the following: 1. emotion opposes reason; 2. emotion is subjective, while reason is objective; 3. emotion lies internal to the subject, while reason is external. With challenges to these dualisms, one of the more interesting questions that has surfaced is the idea of emotional appropriateness in a particular context. Here, consider a widely held belief in the United States associates racialized groups (...) with specific emotions—most notably African American women with anger. Clearly these emotional attributions are essentialistic--and hence racist. But this response is too easy. The acknowledgement that emotion lies both internally in the subject and externally in the world opens the possibility of attributing an emotional temperament to a population group. Yet if an identity group has an emotional temperament, can they be accountable for emotionally appropriate behavior? (shrink)

I suggest that the current situation in quantum field theory (QFT) provides some reason to question the universal validity of ontological reductionism. I argue that the renormalization group flow is reversible except at fixed points, which makes the relation between large and small distance scales quite symmetric in QFT, opening up at least the technical possibility of a non-reductionist approach to QFT. I suggest that some conceptual problems encountered within QFT may potentially be mitigated by moving to an alternative picture (...) in which it is no longer the case that the large supervenes on the small. Finally, I explore some specific models in which a form of non-reductionism might be implemented, and consider the prospects for future development of these models. (shrink)

This book deals with a topic that has been largely neglected by philosophers of science to date: the ability to refer and analyze in tandem. On the basis of a set of philosophical case studies involving both problems in number theory and issues concerning time and cosmology from the era of Galileo, Newton and Leibniz up through the present day, the author argues that scientific knowledge is a combination of accurate reference and analytical interpretation. In order to think well, we (...) must be able to refer successfully, so that we can show publicly and clearly what we are talking about. And we must be able to analyze well, that is, to discover productive and explanatory conditions of intelligibility for the things we are thinking about. The book’s central claim is that the kinds of representations that make successful reference possible and those that make successful analysis possible are not the same, so that significant scientific and mathematical work typically proceeds by means of a heterogeneous discourse that juxtaposes and often superimposes a variety of kinds of representation, including formal and natural languages as well as more iconic modes. It demonstrates the virtues and necessity of heterogeneity in historically central reasoning, thus filling an important gap in the literature and fostering a new, timely discussion on the epistemology of science and mathematics. (shrink)

Just as the nation is imagined and produced through everyday rhetoric and maps and flags, it is also constructed on the skin, and through bodies, by different types of corporeal `flagging'. In this article, I use two examples of contemporary surgical procedures to explore these dynamics. Aesthetic surgeries on `white' subjects are not often interrogated for their racializing effects, but I use the concept of `flagging' to explore how these surgeries work in the UK to align `white' bodies with a (...) white nation. US media coverage of Iraq invasion veterans with prosthetic limbs circulates narratives of heroism and patriotism, and I explore how the apparent `visibility' of these limbs works to re-embed notions of the US as a transcendent Christian nation. In these two examples of corporeal modification, the nation is `flagged' on the skin, reiterating relationships of belonging that echo practical and conceptual links with property. Propertied belonging — possessive and constitutive — unfolds through bodies, producing whiteness not only as property itself, but also as unmarked, habitual terrain. (shrink)

Some fictions seem to involve branching time, where one time series ‘splits’ into two or two time series ‘fuse’ into one. We provide a new framework for thinking about these fictional representations: not as representations of branching time series but rather as branching representations of linear time series. We explain how branching at the level of the representation creates a false impression that the story describes a branching of the time series in the fictional world itself. This involves explaining away (...) the illusion of various causal connections which may at first appear essential to understanding the story as a unified whole. This provides a more accurate account of the relationship between the representation and what is represented, which in turn reveals the extent to which it is legitimate to draw conclusions about actual time from fictional representations. (shrink)

Volume 24, Issue 8, August 2024, Page 88-90.

Lower respiratory tract infections are a leading cause of paediatric morbidity and mortality worldwide. Children in low-income countries are disproportionately affected. This is in large part due to limitations in healthcare resources and medical technologies. Mechanical ventilation can be a life-saving therapy for many children with acute respiratory failure. The scarcity of functioning ventilators in low-income countries results in countless preventable deaths. Some hospitals have attempted to adapt to this scarcity by using hand-bag ventilation, as either a bridge to a (...) mechanical ventilator, or until clinical improvement occurs rendering mechanical ventilation no longer necessary. In instances of hand-bag ventilation, an endotracheal tube is first placed. Family members are then asked to play the role of a ventilator, manually compressing a bag repeatedly to inflate the child’s lungs. This approach is fraught with numerous ethical challenges. A careful examination of the data and a nuanced approach to the ethical considerations are imperative. Ethical arguments in support of and in opposition to allowing parental hand-bag ventilation are explored, including the best interests of the child, the child’s right to an open future, beneficence and parental protection, legitimising substandard care, and finally, contextual concerns. An algorithmic, potentially ethically permissible approach to parental participation in manual ventilation is proposed. (shrink)

Section: Lectures Keywords: History of analytic philosophy, Moore, Sidgwick, Russell, McTaggart, A-theory, B-theory, presentism Disciplines: Philosophy The ‘new realist’ G E Moore is hardly known as a metaphysician of time, yet I argue his 1910–11 lectures, later published as _Some Main Problems of Philosophy_, offer the first substantial English-language defence of presentism and the A-theory. This paper contextualises Moore’s positions, stressing his intellectual connections with J M E McTaggart and Bertrand Russell; explores his Common Sense metaphysics of time; and argues (...) that his time realism owes a great debt to ‘old realist’ Henry Sidgwick. (shrink)

The Covid-19 pandemic elevated global attention to the complex problem of allocating and disseminating newly approved vaccines. Following early calls for vaccine equity,1 global health leaders made progress but struggled to fully realize distribution goals.2 With respect to vaccination rates, low and middle income countries have not achieved full parity with high income countries.3 In this issue, Harmon, Kholina, and Graham follow longstanding critiques of market-based vaccine procurement to propose “legal and practical solutions for realizing a new access to vaccines (...) environment”4 that will, they suggest, further the goal of global health justice. (shrink)

Most discussions of Leibniz's metaphysics of time and space begin and end with the correspondence between Leibniz and Samuel Clarke, Newton's friend and defender. But Leibniz's ideas about time and space are far richer than this exchange suggests, and Michael Futch shows that the study of those investigations will enhance current discussion among philosophers and cosmologists. Futch's scholarly attention to a wide range of texts is matched by his philosophical acuity. His detailed expositions of texts are not tedious or pedantic (...) because he never fails to bring out their philosophical interest and pertinence. So, too, the book's bibliography is especially valuable.The book opens with a discussion of Newton's substantivalism, which treats time and space as substance-like structures that exist independent of the objects located in them, versus Leibniz's reductionism, which holds time and space to be merely relations, ontologically dependent on the things that exist: space is the order of coexistences, time the order of successions. Futch gives useful historical background that explains why the debate takes the form that it does and what. (shrink)

Surgeries inevitably raise questions of bodily integrity: how the post-surgical body reframes (or does not reframe) its experiences of functionality to incorporate new features. Nevertheless, when we try to define or delimit the concept of bodily integrity, it becomes increasingly important to think about how the physical and social unease caused by some forms of surgeries sits alongside the more transformative potential of surgical bodily modification. This article focuses on aesthetic genital surgeries on infants with disorders of sex development (DSD, (...) previously termed ‘intersex’ conditions). Using the work of Pierre Bourdieu and Elizabeth Freeman on time, bodies and ‘chrononormativity’, this article excavates not only the temporalities that produce what I would term ‘chrono-abnormalities’ of sex development, but also the temporalized medical responses, including surgeries, which retrieve ‘abnormal’ bodies into more normative time-lines. My conclusion is that when DSD-affected individuals experience aesthetic genital surgeries as painful and full of social unease this is not necessarily because the pre-surgical body was the ‘natural’, ‘whole’ or ‘intact’ body prior to surgery. Instead, it is because these surgeries interrupt what Bourdieu would term a sense of corporeal ‘immersion into the forthcoming’; an immersion which, in his theory of time as social action, is intimately linked with social power and possibilities. (shrink)

The close association of particular races with particular classes invites a means to exhibit disdain for a race via class. Class and race do not simply occupy a list of social problems, because generally, specific races correlate with particular classes. Racism is presently unacceptable, but not classism. We may feel sympathy for the poor, but we do not refrain from disdain. The disdain of the poor centers on Neoclassical economics’ insistence on choice in regards to class. The language of choice (...) does not circumscribe race. Michel Foucault’s work illustrates that the persistent correlation of race and class is not merely sociological but conceptual. Such close associations of particular races with particular classes serve as a means to generate essentialisms that express racism through classism. (shrink)

Tree-chopping in the Aeneid has long been seen as a disturbingly violent symbol of the Trojans' colonization of Italy. The paper proposes a new reading of the poem which sees Aeneas as progressive extirpator not just of foreign rivals but also of his own Trojan relatives. Although the Romans had no family “trees” as such, their genealogical stemmata (“garlands”) had “branches” (rami) and “stock” (stirps), and their vocabulary of family relationships takes many of its metaphors from planting, adoption, and uprooting, (...) while plant life is often described in human metaphors. Imperial historians use the growth and collapse of trees to mark the rise and fall of dynasties; natural historians like Columella and Pliny use metaphors of adoption, abortion, and adultery to characterize the perversions of agriculture and horticulture. It is thus no coincidence that Aeneas' encounters with Hector, Priam, Deiphobus, and others often take place against a background of real or metaphorical trees (tree similes, headless or mutilated human trunks, ancient trees and woods). These encourage us to see an element of dynastic encroachment in scenes that look pious and peaceable but confirm Aeneas' ascendancy and claim to Trojan succession. The Polydorus episode in particular can be read not just as a grotesque interlude but as a nightmare about endlessly reproducing heirs; one loose strand from Priam's house is allowed to remain, while Virgil deals imperfectly with the problem of Aeneas' own successors. The paper ends by re-examining Virgil's account of grafting in Georgics 2 and arguing that it is viewed positively, perhaps in order to cast Augustus' adoption of heirs as a miracle solution. (shrink)

The consent and community engagement process for research with Indigenous communities is rarely evaluated. Research protocols are not always collaborative, inclusive or culturally respectful. If participants do not trust or understand the research, selection bias may occur in recruitment, affecting study results potentially denying participants the opportunity to provide more knowledge and greater understanding about their community. Poorly informed consent can also harm the individual participant and the community as a whole. Invited by local Aboriginal community leaders of the Fitzroy (...) Valley, the Kimberley, Western Australia, The Picture Talk project explores the consent process for research. Focus groups of Aboriginal community members were conducted to establish preferences for methods of seeking individual consent. Transcripts were analysed through NVivo10 Qualitative software using grounded theory with inductive and deductive coding. Themes were synthesised with quotes highlighted. Focus groups with Aboriginal community members were facilitated by a Community Navigator as a cultural guide and interpreter and a researcher. Participants were recruited from all main language groups of the Fitzroy Valley – Gooniyandi, Walmajarri, Wangkatjungka, Bunuba and Nikinya. Participants were aged ≥18 years, with 5 female groups and one male group. Themes identified include: Reputation and trust is essential; The Community Navigator is key; Pictures give the words meaning – milli milli versus Pictures; Achieving consensus in circles; Signing for consent; and Research is needed in the Valley. Aboriginal communities of the Fitzroy Valley recommend that researchers collaborate with local leaders, develop trust and foster a good reputation in the community prior to research. Local Aboriginal researchers should be employed to provide cultural guidance throughout the research process and interpret local languages especially for elders. Pictures are preferred to written text to explain research information and most prefer to sign for consent. The Fitzroy Valley welcomes research when collaborative and for the benefit of the community. Future research could include exploring how to support young people, promote health screening and improve understanding of medical knowledge. (shrink)

Despite having paved the way for face, womb and penis transplants, hand transplantation today remains a small hybrid of reconstructive microsurgery and transplant immunology. An exceptionally limited patient population internationally complicates medical researchers’ efforts to parse outcomes “objectively.” Presumed functional and psychosocial benefits of gaining a transplant hand must be weighed in both patient decisions and bioethical discussions against the difficulty of adhering to post-transplant medications, the physical demands of hand transplant recovery on the patient, and the serious long-term health (...) risks of immunosuppressant drugs. This paper relates five narratives of hand transplantation drawn from an oral history project to show how narrative methods can and should inform ethical evaluations and the clinical process of hand transplantation. The interviews with patients and their partners analyzed here lead us to suggest that qualitative accounts of patient experiences should be used to complement clinical case studies reported in medical journals and to help develop instruments to assess outcomes more systematically. (shrink)

This article draws on in-depth interviews with nine white, middle-class, male-to-female transsexuals to examine how they produce and experience bodily transformation. Interviewees’ bodywork entailed retraining, redecorating, and reshaping the physical body, which shaped their feelings, role-taking, and self-monitoring. These analyses make three contributions: They offer support for a perspective that embodies gender, further transsexual scholarship, and contribute to feminist debate over the sex/gender distinction. The authors conclude by exploring how viewing gender as embodied could influence medical discourse on transsexualism and (...) have personal and political consequences for transsexuals. (shrink)

This article examines five different Medical-Legal Partnerships associated with Yale Law School in New Haven, Connecticut to illustrate how MLP addresses the social determinants of poor health. These MLPs address varied and distinct health and legal needs of unique patient populations, including: 1) children; 2) immigrants; 3) formerly incarcerated individuals; 4) patients with cancer in palliative care; and 5) veterans. The article charts a research agenda to create the evidence base for quality and evaluation metrics, capacity building, sustainability, and best (...) practices; it also focuses specifically on a research agenda that identifies the value of the lawyers in MLP. Such a focus on the “L” has been lacking and is overdue. (shrink)

Birdsong is widely analysed and discussed by people coming from both musical and scientific backgrounds. Both approaches provide valuable insight, but I argue that it is only through combining musical and scientific points of view, as well as perspectives from more tangentially related fields, that we can obtain the best possible understanding of birdsong. In this paper, I discuss how my own training as a musician, and in particular as a composer, affects how I listen to and parse birdsong. I (...) identify nine areas of overlap between human music and birdsong, which may serve as starting points both for musical and scientific analysis, as well as for interdisciplinary analysis as practiced in the developing field of “zoomusicology.” Using the hermit thrush (Catharus guttatus) as an example, I discuss how the song of a single species has been described by writers from a variety of disciplines, including music, literature, and the sciences, as well as how we can contextualise these varied perspectives in terms of broader cultural thought trends. I end with discussion of how combining approaches from multiple fields can help us to figure out new questions to ask, can help us identify how our own cultural biases may affect how we hear birdsong, and ultimately can help us develop richer and more nuanced understandings of the songs themselves. (shrink)

In order to consider how best to address relationship concerns with potential research participants arising in this study, we will first describe unique features...

Given that many clinical research studies struggle to meet their recruitment goals, researchers are eager to identify and employ strategies that will maximize reach to eligible and int...

Contemporary hormonal therapy for the menopause has its conceptual origins in the ancient tradition of organotherapy. The popular but pharmacologically inactive precursors of hormonal therapy were developed as part of a resurgence of interest in organotherapy in the 19th century, which coincided with increasing medicalization of the menopause and the view that the ovaries were responsible for the ‘feminine’ identity and wellbeing of women. The subsequent chemical identification of oestrogens allowed the development of pharmacologically active hormonal therapy for the menopause, (...) which was probably first used clinically in the late 1920s. Around this time, emphasis shifted from the ovaries to oestrogen as being responsible for femininity and health, with the menopause and ageing increasingly defined as oestrogen deficiency diseases. Hormonal therapy for the menopause was first used predominantly for women who had a premature menopause. In the 1960s, universal prescription was increasingly promoted as a way of preventing diseases of later life and the perceived ‘defeminization’ of women by menopause. Scientific evidence regarding the risks and benefits of hormonal therapy for the menopause has been accruing over the last 70 years; its interpretation has been affected by background beliefs regarding the effects of oestrogen and the menopause on women. (shrink)