This paper develops and defends a paradigm-based explanation of respect. Paradigm-based explanations propose to illuminate subject matter that are basically disunified, by identifying a form of them (“the paradigm”) that is then shown to be explanatorily basic to the subject as a whole. This explanatory strategy is well-suited to the subject of respect, which is widely agreed to encompass two distinct kinds, appraisal respect and recognition respect. Accordingly, the paper sets out to determine which of these two kinds is paradigmatic (...) and which, derivative. It begins by advancing a novel account of appraisal respect (“perspectival respect”), which it also hypothesizes is respect in its paradigmatic form. On this hypothesis, perspectival respect is paradigmatic in virtue of its apparent “point” or function, which is that it constitutively aims at understanding another person’s perspective on things. The paper then tests the viability of this hypothesis by showing how one central form of recognition respect (“respect for persons”) can reasonably be understood to derive from respect in its paradigmatic form, by showing how it is illuminated by the aim of interpersonal understanding. (shrink)

In the field of clinical practice, there does not seem to be too much contention about what schizophrenia is, at least from a high level. After all, there are various diagnostic systems and guidelines, all of which point toward schizophrenia as a psychotic syndrome which likely forms a continuum with other psychotic disorders. It may sound obvious that, according to the current definitions, the major commonality between schizophrenia and all other psychoses is psychotic symptoms; more precisely, delusions and hallucinations. Any (...) description, or ‘phenomenology’ as most clinicians view it, can be found in these diagnostic manuals. However, is there anything at all that sets schizophrenia apart from the other... (shrink)

RPC.2 The individual’s measure of consequences is proportionate to the circle of his outlook. His horizons may lie so near that he can only measure at short range. But, whether they be near or far, he can only judge of consequences as proximately or remotely touching himself. His judgment may err; his motive remains always the same, whether he be conscious of it or not. RPC.3 That motive is necessarily egoistic, since no one deliberately chooses misery when..

This paper addresses the topic of bioethics in reproductive medicine from the perspective of the religious implications for the field. The assumption underlying the approach is that religion remains a factor that influences the field of bioethics even in a secularized postmodern society. The first part of the paper analyses the main bioethical issues which mark obstetrics and gynecology, uttering that the four basic principles of bioethics are available both in obstetrics and gynecology and must be applied in association with (...) the practitioner’s virtues. The second part of the paper focuses on the main directions that guide the debate on the presence of religion in the field of bioethics, with a special interest in their relevance for reproductive medicine. Despite the difficulties implied by the task of advocating for the place of religion at the secular table of deliberation in medical ethics, the relevance of religion for bioethics cannot be ignored. (shrink)

In Gendered Readings of Change, Clara Fischer develops a unique theory of change by drawing on American philosophy and contemporary feminist thought. Via a select history of ancient Greek and Pragmatist philosophies of change, she argues for a reconstruction of transformation that is inclusive of women's experiences and thought. With wide-ranging analysis, this book addresses ontological, moral, epistemological, and political questions, and includes an insightful exploration of the philosophies of Parmenides, Aristotle, John Dewey, Iris Young, and Jane Addams.

We address a recent proposal concerning ‘surplus structure’ due to Nguyen et al.. We argue that the sense of ‘surplus structure’ captured by their formal criterion is importantly different from—and in a sense, opposite to—another sense of ‘surplus structure’ used by philosophers. We argue that minimizing structure in one sense is generally incompatible with minimizing structure in the other sense. We then show how these distinctions bear on Nguyen et al.’s arguments about Yang-Mills theory and on the hole argument.

What is the Gioconda laughing at?, or, Why the lives of women are not in art.

Universities increasingly play an important role in entrepreneurship, which has contributed to gender equality in the business world. The aim of this study is to establish a causal model of entrepreneurial intentions and explore it by gender, based on the dimensions of the Theory of Planned Behavior, and how these are mediated by the individuals’ resilience and psychological well-being. The previous work experience was considered as one of the control variables, in order to analyze whether this influence the entrepreneurial intention. (...) With a convenience sample of 644 Portuguese students, Structural Equation Modeling was used. For a better understanding, multivariate analyses were performed and each one was individually reported, and for appropriate comparisons by gender, the t-student test was used. The comparison of means, between genders, showed that there are differences only between perceived behavioral control, subjective norm, and entrepreneurial intention, with women scoring the highest values, and psychological well-being, with men scoring the higher. A serial mediation path was performed, and psychological resilience was found to mediate a significant effect between perceived behavioral control and intention in females, but not in males. It also mediates a significant effect between attitude and intention in females, but not in males. These results show that attitude is a determining factor for females to become entrepreneurs. Finally, after discussing the results, theoretical and practical contributions are analyzed, with regard to the field of entrepreneurship in Portugal, and alternatives are pointed out for a more entrepreneurial future, reinforcing the role of higher education institutions. (shrink)

En este artículo buscamos mostrar que, tanto en la filosofía de Schopenhauer como también en la de Bergson, la experiencia estética se constituye como el paradigma del conocimiento intuitivo. A diferencia de lo que establece la teoría kantiana, para Schopenhauer y Bergson la intuición no sólo es la única forma de conocimiento inmediato, sino que no necesita de conceptos para aprehender aquello dado en la sensibilidad. Asimismo, puesto que actualmente no encontramos demasiada literatura sobre la influencia de Schopenhauer en la (...) filosofía de Bergson, dicho análisis pretende contribuir al establecimiento de los posibles vínculos entre ambas teorías. (shrink)

Feminist Interpretations of William James is the third volume on a classical pragmatist in the generally excellent Penn State book series, Re-Reading the Canon. The series dedicates itself to a reconstruction of the work of prominent philosophers, and has already brought a critical, feminist perspective to the lives and thought of Jane Addams and John Dewey. This latest installment of the series is a welcome and lively contribution on William James, and adds significantly to the series’ wider reconstructive project, which (...) typically highlights and critiques a philosopher’s problematic, sexist assumptions; examines the effects such assumptions may have had on the thinker’s wider body of work; re-inscribes women’s... (shrink)

En este artículo se presenta una interpretación de la crítica de la economía política de Marx como teoría filosófica: una teoría de la apariencia que tiene sus raíces en la intervención kantiana en la historia de la metafísica. En primer lugar, se presenta el proyecto de la crítica de la economía política como una crítica de la “apariencia real” “objetiva” [ realer, gegenständlicher Schein ]. A continuación, se apunta a fetichismo y mistificación como las categorías centrales de esta teoría de (...) la apariencia marxiana. Después se precisa su origen y posibilidad en el espacio filosófico abierto por Kant y Hegel, que sientan las bases de una teoría de la apariencia propiamente moderna. Finalmente, se profundiza en esta relación entre Marx y Kant mostrando que es posible clarificar tanto las diferencias como los contenidos del fetichismo y la mistificación al hilo de las dos clases de apariencia pensadas por Kant -según la distinción de Lebrun-, “apariencia lógica” y “apariencia trascendental”. (shrink)

The cyclic GMP‐AMP synthase–stimulator of interferon genes (cGAS‐STING) pathway is central for the initiation of anti‐tumoural immune responses. Enormous effort has been made to optimise the design and administration of STING agonists to stimulate tumour immunogenicity. However, in certain contexts the cGAS‐STING axis fuels tumourigenesis. Here, we review recent findings on the regulation of cGAS expression and activity. We particularly focus our attention on the DNA‐dependent protein kinase (DNA‐PK) complex, that recently emerged as an activator of inflammatory responses in tumour (...) cells. We propose that stratification analyses on cGAS and DNA‐PK expression/activation status should be carried out to predict treatment efficacy. We herein also provide insights into non‐canonical functions borne by cGAS and cGAMP, highlighting how they may influence tumourigenesis. All these parameters should be taken into consideration concertedly to choose strategies aiming to effectively boost tumour immunogenicity. (shrink)

In 2018, Irish citizens voted overwhelmingly to repeal the Eighth Amendment to the Constitution to allow for the introduction of a more liberal abortion law. In this article, I develop a retrospective reading of the stubborn persistence of the denial of reproductive rights to women in Ireland over the decades. I argue that the ban’s severity and longevity is rooted in deep-seated, affective attachments that formed part of processes of postcolonial nation-building and relied on shame and the construction of the (...) Irish nation as a particular, gendered place. The article develops the notion of ‘gendered displacement’ to conceptualise abortion travel in the context of the history of women’s coercive confinement, and provides an affective, feminist reading of the interlinkages between place and nationhood. It also draws on three cases—the X, Y and Z cases—to illustrate the centrality of place and women’s occupation of space to the analysis of Ireland’s abortion ban, which should be read in the wider context of the legacy of what I term the ‘affective politics of place’. (shrink)

COVID-19 is compromising all aspects of society, with devastating impacts on health, political, social, economic and educational spheres. A premium is being placed on scientific research as the source of possible solutions, with a situational imperative to carry out investigations at an accelerated rate. There is a major challenge not to neglect ethical standards, in a context where doing so may mean the difference between life and death. In this paper we offer a rubric for considering the ethical challenges in (...) COVID-19 related research, in the form of an ethics toolkit for global research developed at the University of Edinburgh in collaboration with more than 200 global researchers from around the world. This toolkit provides a framework to support confrontation of ethical conflicts through the integrated and iterative analysis of Place, People, Principles and Precedents, throughout the research journey. Two case analyses are offered to exemplify the utility of the toolkit as a flexible and dynamic tool to promote ethical research in the context of COVID-19. (shrink)

Patients with psychotic disorders experience a range of reality distortions. These often include auditory-verbal hallucinations, and thought insertion to a lesser degree; however, their mechanisms and relationships between each other remain largely elusive. Here we attempt to establish a integrative model drawing from the phenomenology of both AVHs and TI and argue that they in fact can be seen as ‘spectra’ of experiences with varying degrees of agency and ownership, with ‘silent and internal own thoughts’ on one extreme and ‘fully (...) external and clearly audible voices’ in the absence of a speaker on the other. We believe a spectral model will add emphasis to the continuity of experience and help to better understand how one type of psychotic symptom may interact with another, and put forward the argument that the experience of TI itself is not sufficient to classify as a delusion. In addition we aim to discuss some of the conceptual issues surrounding AVHs and TI with first-person accounts and current philosophical and neuropsychological theories in mind. We propose that the mechanisms behind AVHs and TI are more complex than source-monitoring deficits; indeed, to understand such phenomena one must appreciate that their very ‘existence’ and ‘reality’ as experienced by the individual have much deeper implications and meaning, both philosophically and clinically. (shrink)

Partindo da tese de Pembroke, segundo a qual a doutrina da oikeiosis é umapeça essencial da filosofia estóica, procuramos demonstrar que é justamenteessa doutrina, que assegura a perfeita coesão entre Física e Ética na Escolaestóica. Para os estóicos, virtude é viver segundo a Natureza, ela será odesenvolvimento de um dom natural, a oikeiosis, a capacidade de todo servivo de reconhecer a si mesmo e aquilo que lhe é apropriado. Conciliando asinterpretações de Pohlenz e de White,entendemos com Chrysippo que as duas (...) naturezas se completam e que aordem racional é interior e exterior ao homem. Não há portanto contradiçãoentre naturalismo e racionalismo no Estoicismo.Partant de la thèse de Pembroke, selon laquelle la doctrine de l’oikeiosis estune pièce maîtresse de la philosophie stoïcienne, nous essayons de montrerque c’est justement cette doctrine qui assure la parfaite cohésion entrePhysique et Ethique dans l’Ecole stoïcienne. Pour les stoïciens, la vertu c’estvivre selon la Nature, elle sera le devéloppement d’un don naturel, l’oikeiosis,la capacité qu’a tout être vivant de se reconnaître et de reconnaître ce que luiest approprié. Conciliant les interprétations de Pohlenz et de White,, nous comprennons avec Chrysippe que lesdeux natures se complètent et que l’ordre rationnel est intérieur et extérieurà l’homme. Il n’y a donc pas de contradiction entre naturalisme etrationnalisme dans le Stoïcisme. (shrink)

An in-depth analysis of the recent reform in Italian psychiatry reveals that the relevance of these changes transcends national borders. However, these changes are, from the scientific point of view, worth much more than mere biased pragmatic interest. The reshaping of theory made possible by the transformation of Italian psychiatry in fact opens up new prospects for a scientifically founded form of psychiatric care. Thanks to the new Mental Health Act (No. 180 of 1978),2 it has been possible to set (...) up a type of administrative and institutional organization in which the psychiatric hospital no longer constitutes a functional part of the structures of psychiatric care. This reform thus provides the launching path for a real alternative where current psychiatric ideas and working methods can no longer be accepted as the gospel truth. This paper discusses how a correct problem-definition of psychiatric admission can provide a basis for a correct approach to psychopathological behaviour in a setting where the psychiatric hospital has no role to play and for the consolidation of this new practice. (shrink)

Recent years have witnessed a focus on feeling as a topic of reinvigorated scholarly concern, described by theorists in a range of disciplines in terms of a “turn to affect.” Surprisingly little has been said about this most recent shift in critical theorizing by philosophers, including feminist philosophers, despite the fact that affect theorists situate their work within feminist and related, sometimes intersectional, political projects. In this article, I redress the seeming elision of the “turn to affect” in feminist philosophy, (...) and develop a critique of some of the claims made by affect theorists that builds upon concerns regarding the “newness” of affect and emotion in feminist theory, and the risks of erasure this may entail. To support these concerns, I present a brief genealogy of feminist philosophical work on affect and emotion. Identifying a reductive tendency within affect theory to equate affect with bodily immanence, and to preclude cognition, culture, and representation, I argue that contemporary feminist theorists would do well to follow the more holistic models espoused by the canon of feminist work on emotion. Furthermore, I propose that prominent affect theorist Brian Massumi is right to return to pragmatism as a means of redressing philosophical dualisms, such as emotion/cognition and mind/body, but suggest that such a project is better served by John Dewey's philosophy of emotion than by William James's. (shrink)

We argue that several apparently distinct responses to the hole argument, all invoking formal or mathematical considerations, should be viewed as a unified “mathematical response.” We then consider and rebut two prominent critiques of the mathematical response before reflecting on what is ultimately at issue in this literature.

During the last century procedures for distinguishing between ‘human sciences’ and ‘natural sciences’ have seen a number of changes. Currently, the pre-eminence of the scientific-naturalist paradigm, which led the field throughout the nineteenth century, seems again under discussion on some fundamental issues. In particular, the boundaries between the two sciences - boundaries which were in no case rigid or absolute - are being tested, in a confrontation concerning the very statutes of both disciplines as well as their respective methods.

In this article, I trace the politics of shame in the context of the problematization of women’s bodies as markers of sexual immorality in modern Ireland. I argue that the post-Independence project of national identity formation established women as bearers of virtue and purity and that sexual transgression threatening this new identity came to be severely punished. By hiding women, children, and all those deemed to be dangerous to national self-representations of purity, the Irish state, supported by Catholic moral values (...) and teaching, physically removed its embodied instances of national shame through a system of mass institutionalization. Just as shame entails the covering of one’s blemishes, so the shaming of women deemed to be deviant by church and state involved their covering via incarceration in Magdalen laundries, among other institutions. By assessing recent events highlighted by inquiries into Irish institutions—Magdalen laundries, reformatory and industrial schools, and soon mother and baby homes—in terms of the politics of shame, this article aims to shed light on the pervasiveness of institutionalization in Ireland and the complex relationship between said institutions, gender, sexuality, and nation building in the early decades of the Irish state. (shrink)

Organisations have implemented intensive home-based teleworking in response to global COVID-19 lockdowns and other pandemic-related restrictions. Financial pressures are driving organisations to continue intensive teleworking after the pandemic. Understanding employees’ teleworking inclinations post COVID-19, and how these inclinations are influenced by different factors, is important to ensure any future, more permanent changes to teleworking policies are sustainable for both employees and organisations. This study, therefore, investigated the relationships between the context of home-based teleworking during the pandemic, productivity perceptions during home-based (...) teleworking, and employees’ future teleworking inclinations beyond the pandemic. Specifically, the study examined whether pandemic-teleworking conditions related to the job, and the physical and social environments at home, influenced employees’ FTI, and if perceptions of improved or reduced productivity mediated these relationships. Data were collected during April and May 2020 with a cross-sectional online survey of teleworkers in Germany, Switzerland, the United Kingdom, and other countries during the first COVID-19 lockdowns. Reported FTI were mixed. Most participants reported wanting to telework more post-pandemic compared to before the pandemic; however, 18% wanted to telework less. Hierarchical multiple regression analysis revealed that some teleworking conditions were positively associated with FTI. Other teleworking conditions were not associated with FTI. Perceived changes in productivity mediated the relationship between work privacy fit and FTI. Findings highlight the role of work privacy fit and job demands in influencing pandemic productivity perceptions and teleworking inclinations post-pandemic. Results raise questions about the suitability and sustainability of home-based teleworking for all staff. As organisations plan to increase the proportion of teleworking post-pandemic, this study suggests there is a need to support employees who perceived their productivity to be poor while home-working during the pandemic. (shrink)