제 1장 생명의 시작과 관련된 생명윤리와 입법 제 1절. 인간배아의 도덕적 지위와 헌법상의 지위에 관한 논변 제 2절. 인간복제 연구와 생식권에 관한 윤리논쟁과 입법 제 3절. 인간배아 연구, 체세포복제배아 연구의 윤리논쟁과 입법 제 2장 탄생과 관련된 생명윤리와 입법 제 1절. 체외수정에 관한 윤리논쟁과 입법 제 2절. 난자 공여에 관한 윤리논쟁과 입법 제 3절. 대리모출산에 관한 윤리논쟁과 입법 제 4절. 태아보호와 관련된 윤리논쟁과 낙태죄 입법 제 3장 죽음과 관련된 생명윤리와 입법 제 1절. 생명의 종기로서 뇌사에 관한 윤리논쟁과 입법 제 2절. 안락사, (...) 존엄사와 의사조력자살에 관한 윤리논쟁과 입법 부록. (shrink)

001. 마르크스 철학의 탈현대적 재구성 002. 철학은 세계를 변혁시킬 수 있는가:인간소외와 사회실천의... 003. 이데올로기 개념의 탈현대적 이해 004. 페레스트로이카의 철학적 이해:마르크스주의의 해체와... 005. 마르크스의 자연개념과 생태학적 사회철학 006. 한스 요나스의 생태학적 윤리학:노동과 기술적 유토피아의 한계 007. 포스트마르크스주의의 사회철학적 비평 008. 자니 바티모의 '약한 존재론'과 포스트마르크스주의 009. 허무주의 시대의 책임윤리:세기전환기의 사회철학적 지평 010. 미셸 푸코-권력,지식 그리고 욕망:후기 자본주의 사회의... 011. 위르겐 하버마스-비판적 사회이론과 담론적 실천 012. 후기 자본주의의 생산양식과 삶의 형식:마르크스 유물론의...

I. Wŏnhyo esŏ An Chung-gŭn kkaji -- II. Yu Yŏng-mo esŏ Kim Tae-jung kkaji.

v. 1. ttŭt ŭl sewŏra -- v. 2. Kukpŏp ŭn chiŏmhan kŏt ida -- v. 3. Punsu nŭl nŏmji mara.

BackgroundThe therapeutic effect of deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson's disease (PD) is related to the modulation of pathological neural activities, particularly the synchronization in the β band (13–35 Hz). However, whether the local β activity in the STN region can directly predict the stimulation outcome remains unclear.ObjectiveWe tested the hypothesis that low-β (13–20 Hz) and/or high-β (20–35 Hz) band activities recorded from the STN region can predict DBS efficacy.MethodsLocal field potentials (LFPs) were recorded in (...) 26 patients undergoing deep brain stimulation surgery in the subthalamic nucleus area. Recordings were made after the implantation of the DBS electrode prior to its connection to a stimulator. The maximum normalized powers in the theta (4–7 Hz), alpha (7–13 Hz), low-β (13–20 Hz), high-β (20–35 Hz), and low-γ (40–55 Hz) subbands in the postoperatively recorded LFP were correlated with the stimulation-induced improvement in contralateral tremor or bradykinesia–rigidity. The distance between the contact selected for stimulation and the contact with the maximum subband power was correlated with the stimulation efficacy. Following the identification of the potential predictors by the significant correlations, a multiple regression analysis was performed to evaluate their effect on the outcome.ResultsThe maximum high-β power was positively correlated with bradykinesia–rigidity improvement (rs = 0.549, p < 0.0001). The distance to the contact with maximum high-β power was negatively correlated with bradykinesia–rigidity improvement (rs = −0.452, p < 0.001). No significant correlation was observed with low-β power. The maximum high-β power and the distance to the contact with maximum high-β power were both significant predictors for bradykinesia–rigidity improvement in the multiple regression analysis, explaining 37.4% of the variance altogether. Tremor improvement was not significantly correlated with any frequency.ConclusionHigh-β oscillations, but not low-β oscillations, recorded from the STN region with the DBS lead can inform stimulation-induced improvement in contralateral bradykinesia–rigidity in patients with PD. High-β oscillations can help refine electrode targeting and inform contact selection for DBS therapy. (shrink)