The human intestinal ecosystem, previously called the gut microflora is now known as the Human Gut Microbiota. Microbiome research has emphasized the potential role of this ecosystem in human homeostasis, offering unexpected opportunities in therapeutics, far beyond digestive diseases. It has also highlighted ethical, social and commercial concerns related to the gut microbiota. As diet factors are accepted to be the major regulator of the gut microbiota, the modulation of its composition, either by antibiotics or by food intake, should be (...) regarded as a fascinating tool for improving the human health. Scientists, the food industry, consumers and policymakers alike are involved in this new field of nutrition. Defining how knowledge about the HGM is being translated into public perception has never been addressed before. This raises the question of metaphors associated with the HGM, and how they could be used to improve public understanding, and to influence individual decision-making on healthcare policy. This article suggests that a meeting of stakeholders from the social sciences, basic research and the food industry, taking an epistemological approach to the HGM, is needed to foster close, innovative partnerships that will help shape public perception and enable novel behavioural interventions that would benefit public health. (shrink)

Common‐sense intuition suggests that, when people are engaged in informational exchanges, they communicate so as to be reasonably sure that they perform the exchanges faithfully. Over the years, we have found evidence suggesting that this intuition, which is woven into several influential theories of human communication, may be misleading. We first summarize this evidence and discuss its potential limitations. Then, we present a new study that addresses the potential limitations. A confederate instructed participants to “pick up the skask” from a (...) tray containing six objects and move it to a specific location. Since skask is a non‐word invented by us, participants had to ask for clarification to perform the instruction faithfully. In contradiction with the intuition that people pursue faithfulness when engaged in informational exchanges, 29 of the 48 participants we tested performed the instruction without asking for clarification. We identified a possible cause for this behavior, which occurred more frequently when avoiding the clarification was unlikely to result in an overt consequence (an error in the execution of the instruction that could be noticed by the confederate or the experimenter). Other factors such as individual differences and the specific interpersonal dynamics of the experimental settings, if they played a role at all, did it to an extent that is unlikely to be comparable to that of the role played by overt consequences. Considered together, our various assessments of the extent to which people engage in faithful informational exchanges converge on a simple conclusion: Communicating faithfully is a substantially demanding task, and people often fail at it. We discuss the implications of this conclusion and speculate on its relevance for understanding the evolutionary past of human communication. (shrink)

The goal of this study is to characterize observers’ abilities to discriminate between endogenous and exogenous changes. To do so, we developed a new experimental paradigm. On each trial, participants were shown a dot pattern on the screen. Next, the pattern disappeared and participants were to reproduce it. Changes were surreptuously introduced in the stimulus, either by presenting participants anew with the dot pattern they had themselves produced on the previous trial or by presenting participants with a slightly different dot (...) pattern . We analyzed awareness of the changes and behavioral adaptation to them in a dynamical manner. We observe signal attenuation in the presence of endogenous change, dissociation between self-attribution reports and behavioral effect of agency. We discuss the source of this sensitive attenuation as well as the relation between a minimal or core self and an extended, narrative or autobiographical self. (shrink)

Interoception, the ability to feel the body’s internal sensations, is an essential aspect of emotional experience. There is mounting evidence that interoception is impaired in common mental health disorders and that poor interoceptive awareness is a major contributor to emotional reactivity, calling for clinical interventions to address this deficit. The manuscript presents a comprehensive theoretical review, drawing on multidisciplinary findings to propose a metatheory of reinforcement mechanisms applicable across a wide range of disorders. We present a reconsideration of operant conditioning (...) through the co-emergence model of reinforcement, which is a neurophenomenological account of the interaction between cognition and interoception, and its consequences on behavior. The model suggests that during memory processing, the retrieval of autobiographical memory (including maladaptive cognition) is dependent upon its co-emerging interoceptive cues occurring at the encoding, consolidation and reconsolidation stages. Accordingly, “interoceptive reinforcement” during emotional distress is a common factor to all emotional disorders and a major cause for relapse. We propose that interoceptive desensitization has transdiagnostic benefits, readily achievable through the cultivation of equanimity during mindfulness training and can be integrated in cognitive and behavioral interventions to permit a transdiagnostic applicability. We summarize the contributions of this approach into 10 specific and testable propositions. (shrink)

Healthcare policies developed during the COVID-19 pandemic to safeguard community health have the potential to disadvantage women in three areas. First, protocols for deferral of elective surgery may assign a lower priority to important reproductive outcomes. Second, policies regarding the prevention and treatment of COVID-19 may not capture the complexity of the considerations related to pregnancy. Third, policies formulated to reduce infectious exposure inadvertently may increase disparities in maternal health outcomes and rates of violence towards women. In this commentary, we (...) outline these challenges unique to women’s healthcare in a pandemic, provide preliminary recommendations and identify areas for further exploration and refinement of policy. (shrink)

Ανέκδοτα ψηφίσματα από τη Λάρισσα (3) Συνεχίζοντας τις δΰο προηγούμενες δημοσιεύσεις που αφορούσαν σε ψηφίσματα της Λάρισσας (BCH 128-129 (2005), p. 377-417 ; BCH 130 (2006) [20081, Ρ· 435-483), παρουσιάζουμε εδώ μια τρίτη στήλη, η οποία φέρει τρία κείμενα: δύο ψηφίσματα της Λάρισσας, που ψηφίστηκαν κατά τη διάρκεια της στρατηγείας του Παυσανία, υιού του Θρασυμήδη από τις Φέρες (περίπου 130/129 π. Χ.), το ένα για έναν Αθηναίο φιλόσοφο και το άλλο για τρεις πολίτες της Κω· ένα τρίτο ψήφισμα προέρχεται από (...) τη Συνομοσπονδία των Μολοσσών και ανταμοίβει δικαστές από τη Λάρισσα, οι οποίοι εστάλησαν στην Ήπειρο για να διαιτητεύσουν σε μια διαμάχη μεταξύ Μολοσσών και Ακαρνάνων. Τα κείμενα αυτά, γραμμένα σε θεσσαλική διάλεκτο, η οποία την εποχή εκείνη χρησίμευε στη μεταγραφή εγγράφων της καγκελλαρίας των ελληνιστικών πόλεων σε μια γλώσσα που χάνει προοδευτικά τη συνοχή και την ιδιομορφία της και καταλήγει να διατηρεί μόνο μια «θεσσαλίζουσα» απόχρωση, έχουν αξία για την ιστορία της Λάρισσας, αφού αναφέρονται στην πνευματική ζωή και σε ορισμένες εκφάνσεις των πολιτικών ή οικονομικών δραστηριοτήτων των Λαρισσαίων στο δεύτερο μισό του 2ου αι. π. Χ. (shrink)

This paper provides an overview of developments in the application of game theory to moral philosophy. Game theory has been used in moral theory in three ways. First, as a tool to analyze the function of moral norms. Secondly, to characterize bargaining about moral norms. Thirdly, the paper demonstrates how game theory can make sense of the authority of moral norms in a way that renders the concept suitable for further analysis.

Facticity and the Fate of Reason After Kant is the first history of the concept of facticity. G. Anthony Bruno argues that this concept’s coining, transmission, and repurposing by post-Kantian thinkers leaves a lasting divide concerning the question of whether a science of intelligibility can tolerate brute facts. In the phenomenological tradition, ‘facticity’ denotes undeducibly brute conditions of intelligibility such as sociality, mortality, and temporality. This suggests an affirmative answer to the post-Kantian question. However, the term’s original use in (...) the German idealist tradition is associated with a negative answer: a science of intelligibility must eliminate bruteness in order to be systematic, as Fichte says, or presuppositionless, as Hegel says. Moreover, eliminating bruteness requires a new logic for deducing conditions of intelligibility from reason’s self-contradictions, a dialectical logic that Fichte invents and Hegel develops. In response to the German idealists, Heidegger argues that dialectic ineluctably presupposes brute facts of lived experience, whose interpretation requires a hermeneutics of facticity. The untold history of the concept of facticity thus contains the deepest parting of the ways after Kant, one in which reason is fated to transform from the hand that holds the world to the thrown activity of being-in-the-world. Facticity and the Fate of Reason After Kant explores this transformation while confronting our inheritance of the still-pressing post-Kantian question. (shrink)

L’article inscrit la guerre d’Ukraine dans le cadre d’une politique clausewitzienne de contre-révolution mondiale. Cette guerre interétatique est le résultat du cycle de déploiement des printemps et des soulèvements de la dernière décennie et a des répercussions synchroniques sur un clivage interne qui traverse d’autres pays. L’article se conclut par une vision alternative entre un conflit inter-impérialiste dans lequel l’Europe est menacée par le bloc atlantiste et une dichotomie autocraties/démocraties.

À partir d’auteurs comme Negri, Cocco, Viveiros de Castro et Fanon, cet article discute le devenir-indien comme un concept pour les forces expressives de luttes et de réinvention dans le Sud. À travers de formes concrètes d’intervention, on analyse un mode de résistance à la fois créatif et alternatif, qui prend le contre-pied de l’actuel agenda capitaliste et néo-développementiste.

Meillassoux seeks knowledge of transcendental reality, blaming Kant for the ‘correlationist’ proscription of independent access to either thought or being. For Meillassoux, correlationism blocks an account of the meaning of ‘ancestral statements’ regarding reality prior to humans. I examine three charges on which Meillassoux’s argument depends: (1) Kant distorts ancestral statements’ meaning; (2) Kant fallaciously infers causality’s necessity; (3) Kant’s transcendental idealism cannot grasp ‘the great outdoors’. I reject these charges: (1) imposes a Cartesian misreading, hence Meillassoux’s false assumption that, (...) for Kant, objects don’t exist without subjects; (2) misreads Kant, who infers causality’s necessity from the possibility of experience; (3) casts Kant’s idealism as subjective, ignoring his perspectival portrayal of it. (shrink)

Despite F. W. J. Schelling’s relative exclusion from the ongoing German idealist renaissance in Anglophone scholarship, recent critical and historical engagement with idealist texts affords an unprecedented opportunity to discover the richness and value of his thinking. This volume provides a wide-ranging presentation of Schelling’s original contribution to and internal critique of the basic insights of German idealism, his role in shaping the course of post-Kantian thought, and his sensitivity and innovative responses to questions of lasting metaphysical, epistemological, ethical, aesthetic, (...) and theological importance. The contributing authors offer compelling reasons to regard Schelling as one of Kant’s most incisive interpreters, a pioneering philosopher of nature, a resolute philosopher of human finitude and freedom, a nuanced thinker of the bounds of logic and self-consciousness, and perhaps Hegel’s most effective critic. (shrink)

Phillips & Silverstein offer an exciting synthesis of ongoing efforts to link the clinical and cognitive manifestations of schizophrenia with cellular accounts of its pathophysiology. We applaud their efforts but wonder whether the highly inclusive notion of “context” adequately captures some important details regarding schizophrenia and NMDA/glutamate function that are suggested by work on language processing and cognitive electrophysiology.

Editorial - Dossiê - Ordem Religiosas Medievais: Poder e Sociedade Horizonte, Belo Horizonte, v. 15, n. 48, out./dez. 2017.

Unfortunately, there is a mistake in line 10 of Section 1.2. The correct reference should read: As Kripke pointed out, we can produce one simply by baptizing the string ‘Jack is short’: Jack.

We study the minimal complexity of tilings of a plane with a given tile set. We note that every tile set admits either no tiling or some tiling with.

L’idéalisme transcendantal de type fichtéen et schellingien a été développé à partir d’un certain nombre d’apories concernant, par exemple, la « chose-en-soi », le statut du sujet entre sens interne et externe et l’intersubjectivité. Surtout la version schellingienne du transcendantalisme aboutit à une nouvelle conception de l’ontologie, « post-kan-tienne ». Mais elle est basée sur un déplacement de la problématique kantienne, entamée déjà par Fichte, qui méconnaît radicalement un aspect essentiel de la découverte kantienne, à savoir que l’entendement est fonctionnalité, (...) dans un sens analogue à l’acception promue par Leonhard Euler en mathématiques. (shrink)

Un décret de Trikka trouvé en 1987, le premier que l'on connaisse pour cette cité, honore un Cretois de Tylissos, Orthotimos, fils de Kélaithos, qui devait être un officier au service de la Macédoine. Vers la fin du nr" siècle av. J.-C, il a été honoré par une autre cité thessalienne, Atrax. Le décret de Trikka présente deux particularités de formulaire : la mention d'un privilège appelé isomoiria, celle de tages «à Trikka». L'étude de ces deux expressions conduit à reposer (...) le problème des groupes d'exilés accueillis en Étolie, qui devaient former des communautés auxquelles les Étoliens reconnaissaient un statut de «polis» organisée. Ce décret apporte ainsi un éclairage nouveau sur l'histoire politique de la Thessalie à la fin du ni· siècle av. J.-C. (shrink)

Today childhood takes place within amultimedia context where education, marketingand entertainment operate together in one bigmelting pot. Childhood is commodified, asituation not everybody seems happy with. Dueto increasing exposure with violence and sexualactivities, for example in children's games,children seem to lose the chance to be realchildren. In the discussions about thiscommodified childhood, innocence and nostalgiaseem omnipresent concepts. In this article wefirst analyse the discourse about the innocenceof childhood as presented by Neil Postman inhis bestseller ``The Disappearance ofChildhood.'' Here, childhood is (...) seen as a periodwhich can mainly be characterised in terms of a``not yet.'' However, Postman's view on childhoodpresents only one side of the romanticcontinuum. The other side – in which the childappears as having a nature of her own – can beillustrated by ``On naïve and sentimentalpoetry,'' an essay written by Friedrich Schillerin 1795. Both opposing views on childhood canlead to a different interpretation of theinnocence of childhood. Finally, Schiller'sdichotomy – the naïve versus thesentimental poet – can be seen as a useful legup to the clarification of nostalgia whichseems to go hand in hand with the feeling ofthe loss of childhood. (shrink)

This is a review of the book Metaética: algumas tendências. The book contains papers of three important philosophers in this subject, Peter Railton, Allan Gibbard and Stephen Darwall. Since this book has been published, the study of metaethics has been improved in Brazil. In this review we describe the main aspects of the book, focusing on Railton’s ideas.

This article, originally meant for an Auroville publication, consists mainly, besides the quotations, of a wide range of suggestions related to a transcultural approach to various questions raised by transdisciplinary research. All these suggestions converge on a central focus; the virtual reality of a subject/object interaction that eludes narrow disciplinary restrictions as well as rigid cultural definitions. Here, significantly, etymology seems to lead towards mythical cultural watersheds, just as philology has been offering clues to some fundamental philosophical discoveries, from Nietsche (...) to G. Colli. The recent impact of Orientalist studies leads further into the same initiatic dimension, wherein metaphysics, ontology, aesthetics, linguistics, cosmology and psychology, all blend in a continuum of psychic experience, while variations of conscious awareness could only be described, and not sharply differentiated. All this would point, not only to the emergence of new cognitive methods, but also to correspondingly adequate means of expression. A transcultural approach could, moreover, provide vital links between today's originality and the spiritual traditions of the past, adding thus a sense of cultural continuity to our endeavours in understanding evolution. (shrink)