Quality and service improvement (QSI) research employs a broad range of methods to enhance the efficiency of healthcare delivery. QSI research differs from traditional healthcare research and poses unique ethical questions. Since QSI research aims to generate knowledge to enhance quality improvement efforts, should it be considered research for regulatory purposes? Is review by a research ethics committee required? Should healthcare providers be considered research participants? If participation in QSI research entails no more than minimal risk, is consent required? The (...) lack of consensus on answers to these questions highlights the need for ethical guidance. Three distinct approaches to classifying QSI research in accordance with existing ethical principles and regulations can be found in the literature. In the first approach, QSI research is viewed as distinct from other types of healthcare research and does not require regulation. In the second approach, QSI research falls within regulatory guidelines but is exempt from research ethics committee review. In the third approach, QSI research is deemed to be part of the learning healthcare system and, as such, is subject to a different set of ethical principles entirely. In this paper, we critically assess each of these views. While none of these approaches is entirely satisfactory, we argue that use of the ethical principles governing research provides the best means of addressing the numerous questions posed by QSI research. (shrink)

Landmarks of Scientfic Socialism: Anti-Dühring (German: Herrn Eugen Dührings Umwälzung der Wissenschaft, "Herr Eugen Dühring's Revolution in Science") is a book by Friedrich Engels, which was first published in German in 1878. It had previously been serialised in a periodical called Vorwärts. There were two other German editions during Engels' life. Anti-Dühring was first published in English translation in 1907.The work was perhaps Engels' most important contribution and development within Marxist theory.Eugen Dühring had previously created his own version of socialism, (...) which was supposed to be a replacement for Marxism. This work was supposed to be a defence of Marxism against produced his own version of socialism, intended as a replacement for Marxism from Dühring's attack. (shrink)

This dissertation examines the coherence and applicability of Whitehead's philosophy of organism insofar as that speculative scheme functions as a viable metaphysical basis for his philosophy of civilization. In short, what is offered is an inquiry concerning the metaphysical foundation of Whitehead's theory of civilized society. ;Overall, the metaphysical ground of civilized society is rooted in two tenets fundamental to Whitehead's philosophy: the paradigm of organism, exemplified in the becoming of an actual entity, and two, the essentially social character of (...) order, exemplified in the occurrences of natural events. Of the first, the primary ontological status of actual entities, each a self-creative process of many things in disjunction immanently related into one novel individual, sets the standard in terms of which all other existent things, human beings and civilized societies alike, are ultimately referent. Accordingly, the concepts of prehension and concrescence are most pertinent to the genesis and character of human experience, and thus to the advent of civilized society. The principle of creativity-one-many is likewise essential to the derivation of civilized society, inasmuch as the process of 'many' creatively united into 'one' is a universal archetype of Whitehead's philosophy, whether applied to cosmology or sociology. ;Equally fundamental to the metaphysical foundation of civilized society is Whitehead's conception of a composite organism, i.e., a "society" of actual entities, for it is upon this basis that the hierarchical social order of nature is established, and thereby the civilized order of human society. The occurrence of civilized society is, in this context, simply a highly specialized and unique form of social order made manifest by the impelling drive of creativity, actualized by way of the radical novelty of human mentality and the freedom of individual effort. Civilization is, as Whitehead so aptly puts it, an "adventure of ideas." So too, the question concerning the metaphysical status of civilized society, as an existent thing, as one or many, finds its resolution in conformity with the principles germane to the constitution of any such social organism. (shrink)

The past two decades have seen an explosion of literature on Hume's views about mental representation and intentionality. This essay gives a roadmap of this literature, while arguing for two main interpretive claims. First, Hume aims to naturalize all forms of mental representation and intentionality, that is, to explain them in terms of properties and relations that are found throughout the natural world (not just in minds) and that are not, individually, peculiar to representational or intentional things. Second, Hume holds (...) that the passions are not representational but do have intentionality extrinsically. (shrink)

in the treatise, hume claims to identify many “fictions of the imagination” among both “vulgar” and philosophical beliefs. To name just a few, these include the fiction of one aggregate composed of many parts,1 the fiction of a material object’s identity through change, and the fiction of a human mind’s identity through change and interruption in its existence. Hume claims that these fictions and others like them are somehow defective: in his words, they are “improper,” “inexact,” or not “strict”. I (...) will argue that this claim conflicts with other commitments.. (shrink)

This article explains Hume's conception of the imagination and its relations to our other faculties of thought, highlighting the continuities and discontinuities between his views and those of his Early Modern predecessors. It then presents some of the basic functions that Hume thinks the imagination performs, and surveys some highlights of his science of man, showing how he uses the imagination’s basic functions to explain several important mental phenomena; examines “fictions of the imagination,” which have an important place in his (...) science of man; examines his view that whatever we can clearly imagine is possible; and discusses the relationship between Hume’s theory of the imagination and his skepticism. (shrink)

The essays in this volume share an ambitious interest in investigating death as an individual, social, and metaphorical phenomenon that may be exemplified by themes involving burial rituals, identity, and commemoration. The disciplines represented are as diverse as art history, classics, history, music, languages and literatures, and the approaches taken reflect various aspects of contemporary death studies.

Scientific integrity cannot be adequately ensured by appeals to the ethical principles of individual researchers. Research fraud has become a public scandal, exacerbated by our inability accurately to judge its extent. Current reliance on peer review of articles ready for publication as the sole means to control the quality and integrity of the majority of research has been shown to be inadequate, partly because faults in the research process may be concealed and partly because anonymous peer review is itself imperfect. (...) Consequently, the scientific literature is mixed, with the reader unable always to distinguish the good articles from the bad. Scientific research is subject to market forces that will always provide a motivation for a range of misdemeanours. This has led to a ‘market for lemons’. Regulations, and sanctions against miscreants, need to be modelled on those historically found necessary to limit financial fraud. Practical and effective systems of process control and audit have already been devised to ensure the integrity of clinical and pre-clinical research. These should be adapted for use in a much wider range of research activities. (shrink)

Scientific integrity cannot be adequately ensured by appeals to the ethical principles of individual researchers. Research fraud has become a public scandal, exacerbated by our inability accurately to judge its extent. Current reliance on peer review of articles ready for publication as the sole means to control the quality and integrity of the majority of research has been shown to be inadequate, partly because faults in the research process may be concealed and partly because anonymous peer review is itself imperfect. (...) Consequently, the scientific literature is mixed, with the reader unable always to distinguish the good articles from the bad. Scientific research is subject to market forces that will always provide a motivation for a range of misdemeanours. This has led to a ‘market for lemons’. Regulations, and sanctions against miscreants, need to be modelled on those historically found necessary to limit financial fraud. Practical and effective systems of process control and audit have already been devised to ensure the integrity of clinical and pre-clinical research. These should be adapted for use in a much wider range of research activities. (shrink)

This article delineates two dimensions along which computational models of face processing may vary, and briefly review three such models, the Dailey and Cottrell model; the O'Reilly and Munakata model; and the Riesenhuber and Poggio. It focuses primarily on one of the models and shows how this model is used to reveal potential mechanisms underlying the neural processing of faces and objects—the development of a specialized face processor, how it could be recruited for other domains, hemispheric lateralization of face (...) processing, facial expression processing, and the development of face discrimination. It turns to the Riesenhuber and Poggio model to describe the elegant way it has been used to predict functional magnetic resonance imaging data on face processing. The overall strategy of these modeling efforts is to sample problems that are constrained by neurophysiological and behavioral data, and to stress the ways in which models can generate novel hypotheses about the way humans process faces. (shrink)

This essay gives a new interpretation of Hume's second thoughts about minds in the Appendix, based on a new interpretation of his view of composition. In Book 1 of the Treatise, Hume argued that, as far as we can conceive it, a mind is a whole composed by all its perceptions. But—this essay argues—he also held that several perceptions form a whole only if the mind to which they belong supplies a “connexion” among them. In order to do so, it (...) must contain a further perception or perceptions. But when the perceptions in question are all of those belonging to a given mind—as in the section “Of personal identity” and the Appendix—there cannot be a further perception in that mind, and so those perceptions do not form a whole. Hence, Hume's views were inconsistent. This essay argues that, unlike most others, this interpretation explains his retreat to skepticism in the Appendix. (shrink)

For this second edition, the editors have returned to Austin's original lecture notes, amending the printed text where it seemed necessary.

Owen Flanagan's arguments concerning qualia constitute an intermediate position between Dennett's “disqualification” of qualia and the thesis that qualia represent an insurmountable obstacle to constructive naturalism. This middle ground is potentially attractive, but it is shown to have serious problems. This is brought out via consideration of several classic areas of dispute connected with qualia, including the inverted spectrum, Frank Jackson's thought experiment, Hindsight, and epiphenomenalism. An attempt is made to formulate the basis for a less vulnerable variant on the (...) “middle ground”. (shrink)

The rise of conspiracy culture and the growing influence of conspiracy theories have attracted the attention of scholars from a range of fields. In recent years, Daniel Jolley, Asbjørn Dyrendal, and others have noted the prevalence of conspiracy theories amongst adolescent schoolchildren in Scandinavia and the UK. This article draws on Paulo Freire’s concept of the ‘banking model’ of education to make the case against a ‘debunking’ approach to anticonspiracist education. It argues that conspiracism should be understood as a feature (...) of our culture and as such it should be interrogated rather than dismissed by educators who are engaged in the process of educating for democracy. (shrink)

The ‘real’ issue concerns the status of qualia, that is, the subjective sensory states into which we are thrown when looking at a yellow leaf, hearing a musical chord, sniffing a camembert, or running our fingers over a piece of sandpaper. Is it possible to provide a satisfactory account of such states using only the resources of a materialist functionalism? Or is it the case -- as it has seemed to many, and as it seems to David Chalmers -- that (...) once we have said all there is to say about the physical basis of, and the functional role of, such states, there remains an uneliminable residue: the brute qualitative matter of ‘what it is like’ to sniff the camembert? Since it is extraordinarily hard to tackle this question head-on, we seek the leverage afforded by the notion of the philosopher's zombie, the point being that if we have a coherent intuition to the effect that there is indeed such a residue, then we ought to be able to conceive of the zombie. Just subtract the residue while leaving all the physical/functional stuff in place. Conversely, if it transpires that the notion of the philosopher's zombie breaks down under stress, this would seem to indicate that the intuition of the ineliminable residue is itself problematic. The ‘remedy’ for a belief in zombies is the sort of Dennettian exercise in imagination proposed in this paper. One must be forced to recognize the huge gulf between the simple informational economies of the thermostat, and even the PC, and the amazingly subtle and layered informational economy of a normal human being. Taking the PC, or the severely degraded registrations of actual blindsight victims, as the model, one may fool oneself into thinking one has imagined something when one has not really confronted its detailed implications. This piece will have accomplished its aim if it encourages a few readers to take the latter possibility more seriously than hitherto. (shrink)

The book uses Zen Buddhism as the opening wedge for an extraordinarily wide-ranging exploration of consciousness.

The word processor is a stupid and grossly inefficient tool for preparing text for communication with others. That is the claim I shall defend below. It will probably strike you as bizarre at first sight. If I am against word processors, what do I propose: that we write in longhand, or use a mechanical typewriter? No. While there are things to be said in favor of these modes of text preparation I take it for granted that most readers of this (...) essay will do most of their writing using a computer, as I do. My claim is that there are much better ways of preparing text, using a computer, than the word processor. (shrink)

Austin takes on the problem of other minds, of how to respond to the question ‘how do you know?’, if this question is raised with regard to the thoughts, feelings, sensations, minds of other creatures. This problem has traditionally been understood as the problem of justifying our belief in the existence of other minds. Austin argues that believing in other persons, in authority and testimony, is an essential part of the act of communicating, and as such is an (...) irreducible part of our experience. While we can state certain advantages of communicative performances, there is no justification for our doing them as such. (shrink)

Hume’s discussion of space in the Treatise addresses two main topics: divisibility and vacuum. It is widely recognized that his discussion of divisibility contains an answer to Bayle, whose Dictionary article “Zeno of Elea” presents arguments about divisibility as support for fideism. It is not so widely recognized that, elsewhere in the same article, Bayle presents arguments about vacuum as further support for fideism. This paper aims to show that Hume’s discussion of vacuum contains an answer to these vacuum-based fideistic (...) arguments. Key to this answer is a distinction between two ways in which vacuum was conceived in the early modern period: i) as a genuine thing that has spatial properties, and yet is immobile, indivisible, and penetrable ; ii) as a mere absence of spatial things. This paper also aims to provide a novel defense of Hume against the long-standing objection that he is inconsistent in denying that we can conceive of a vacuum, while allowing that we can conceive of “invisible and intangible distance.” As I interpret him, Hume consistently denies that we can conceive of a positive vacuum, while allowing that we can conceive of two or more objects’ being arranged so as to have privative vacuum between them. (shrink)

First published in 1962, contains the William James Lectures delivered at Harvard University in 1955. It sets out Austin's conclusions in the field to which he directed his main efforts for at least the last ten years of his life. Starting from an exhaustive examination of his already well- known distinction of performative utterances from statements, Austin here finally abandons that distinction, replacing it by a more general theory of 'illocutionary forces' of utterances which has important bearings on (...) a wide variety of philosophical problems. (shrink)

Recent events and advances address the possibility of cloning endangered and extinct species. The ethics of these types of cloning have special considerations, uniquely different from the types of cloning commonly practiced. Cloning of cheetahs may be ethically appropriate, given certain constraints. However, the ethics of cloning extinct species varies; for example, cloning mammoths and Neanderthals is more ethically problematic than conservation cloning, and requires more attention. Cloning Neanderthals in particular is likely unethical and such a project should not be (...) undertaken. It is important to discuss and plan for the constraints necessary to mitigate the harms of conservation and extinct cloning, and it is imperative that scientific and public discourse enlighten and guide actions in the sphere of cloning. (shrink)

McCoy and colleagues (2023) offer a reflective framework for data ethics and governance with several historical bioethics principles as a foundation. Their framework is one among a plethora of othe...

Interest in John Maynard Keynes has increased significantly over the past decade with the publication of his collected writings, increased access to his unpublished papers, and the resulting explosion of secondary literature. Responding to this renewed attention, this collection brings together economists and historians of economics with scholars from philosophy and other related fields to reconsider Keynes’s work and its legacy. Several of these essays look at Keynes not simply as an economist, but more broadly as a philosopher. Special attention (...) is directed to his views on aesthetics and moral philosophy, as well as his contributions as a probability theorist. The development of the Keynesian heritage is also considered: How did Keynesian ideas become assimilated and domesticated into the mainstream of economic thought—to the point of becoming dominant as the orthodoxy of the economics profession? What was the relationship between postwar British conservatives, Keynes’s work, and Britain’s relative economic decline? The archivist in charge of Keynes’s papers provides an additional vantage point on Keynes’s working methods and the broad range of scholars interested in his writings. Finally, all of the essays are followed by a responder’s comments, thus providing an exchange of viewpoints. _Contributors. _A. W. Coats, Allin F. Cottrell, Jacqueline Cox, William Darity, John Davis, Robert Dimand, Peter Groenewegen, Kevin Hoover, Henry E. Kyburg Jr., David Laidler, Michael S. Lawlor, Greg Lilly, D. E. Moggridge, R. M. O’Donnell, Kerry Pearce, Jochen Runde, Teddy Seidenfeld, J. D. Tomlinson. (shrink)

Pragmatic comparative effectiveness randomized controlled trials evaluate the effectiveness of one interventions under real-world clinical conditions. The results of ceRCTs are often directly generalizable to everyday clinical practice, providing information critical to decision-making by patients, clinicians, and healthcare policymakers. The PRECIS-2 framework identifies nine domains that serve to score a trial on a continuum between very explanatory to very pragmatic. According to the framework, pragmatic trials may have one or more of the following features: there are fewer eligibility criteria for (...) participants, in an... (shrink)

This book is the one to put into the hands of those who have been over-impressed by Austin 's critics....[Warnock's] brilliant editing puts everybody who is concerned with philosophical problems in his debt.

The imagination has a central place in Hume’s science of human nature: he attributes numerous important features of our mental and social lives to this faculty. However, few studies of his thought have made it their focal topic. The Imagination in Hume’s Philosophy is intended to address “this lack in the literature” (x).

Eukaryogenesis is widely viewed as an improbable evolutionary transition uniquely affecting the evolution of life on this planet. However, scientific and popular rhetoric extolling this event as a singularity lacks rigorous evidential and statistical support. Here, we question several of the usual claims about the specialness of eukaryogenesis, focusing on both eukaryogenesis as a process and its outcome, the eukaryotic cell. We argue in favor of four ideas. First, the criteria by which we judge eukaryogenesis to have required a genuinely (...) unlikely series of events 2 billion years in the making are being eroded by discoveries that fill in the gaps of the prokaryote:eukaryote “discontinuity.” Second, eukaryogenesis confronts evolutionary theory in ways not different from other evolutionary transitions in individuality; parallel systems can be found at several hierarchical levels. Third, identifying which of several complex cellular features confer on eukaryotes a putative richer evolutionary potential remains an area of speculation: various keys to success have been proposed and rejected over the five-decade history of research in this area. Fourth, and perhaps most importantly, it is difficult and may be impossible to eliminate eukaryocentric bias from the measures by which eukaryotes as a whole are judged to have achieved greater success than prokaryotes as a whole. Overall, we question whether premises of existing theories about the uniqueness of eukaryogenesis and the greater evolutionary potential of eukaryotes have been objectively formulated and whether, despite widespread acceptance that eukaryogenesis was “special,” any such notion has more than rhetorical value. (shrink)

This monograph examines the domain of classical political economy using the methodologies developed in recent years both by the new discipline of econo-physics and by computing science. This approach is used to re-examine the classical subdivisions of political economy: production, exchange, distribution and finance. The book begins by examining the most basic feature of economic life – production – and asks what it is about physical laws that allows production to take place. How is it that human labour is able (...) to modify the world? It looks at the role that information has played in the process of mass production and the extent to which human labour still remains a key resource. The Ricardian labour theory of value is re-examined in the light of econophysics, presenting agent based models in which the Ricardian theory of value appears as an emergent property. The authors present models giving rise to the class distribution of income, and the long term evolution of profit rates in market economies. Money is analysed using tools drawn both from computer science and the recent Chartalist school of financial theory. Covering a combination of techniques drawn from three areas, classical political economy, theoretical computer science and econophysics, to produce models that deepen our understanding of economic reality, this new title will be of interest to higher level doctoral and research students, as well as scientists working in the field of econophysics. (shrink)