This Oxford Reader contains 140 essential readings covering the most important debates in the Western political tradition and presents samples of the major political ideologies. Issues discussed include; the role of human nature in determining social arrangements; the political significance of gender differences; the justification for the powers of the state; democracy and the rights of minorities; the tension between liberty and equality; the way in which resources ought to be distributed; and international relations. Authors range from Plato and Aristotle (...) to Martin Luther King, Michel Foucault and Isaiah Berlin. (shrink)

We propose an ideal experiment enabling the simultaneous assignment of the objective values, 0 or 1, of two incompatible properties of a system made up of two separated, non-interacting spin particles when a strict interpretation of the criterion of reality of Einstein, Podolsky and Rosen is adopted. We compare this experiment with the physical situation involving two-value observables of a system of two correlated spin-1/2 particles envisaged by Bohm; in particular, we show its inadequacy in the dual assignment at (...) issue. Finally, we discuss a number of questions of interpretation of the consistent quantum theory highlighted by our experiment. (shrink)

In The Early Modern Subject, Udo Thiel explores early modern writings spanning approximately the seventeenth century to the first half of the eighteenth century on two topics of self consciousness, the human subject’s ‘awareness or consciousness of one’s own self’, and personal identity, the human subject’s tendency to regard one’s own self as the same identical self or person that persists through time (p. 1). The aim of the book is twofold. First, to provide an account of the development of (...) self-consciousness and personal identity covering prominent French, British, and German thinkers such as Descartes, Locke, Leibniz, Wolff, and Hume, as well as their critics, their followers, and to ‘critically evaluate their contributions’ (p. 3). The second aim is to situate the contributions of these philosophers within their historical context. In this review I summarize and evaluate The Early Modern Subject. (shrink)

We single out an alternative, strict interpretation of the Einstein-Podolsky-Rosen criterion of reality, and identify the implied extensions of quantum correlations. Then we prove that the theorem of Bell, and the non-locality theorems without inequalities, fail if the new extensions are adopted. Therefore, these theorems can be interpreted as arguments against the wide interpretation of the criterion of reality rather than as a violation of locality.

This book offers a collection of essays in contemporary political philosophy from a wide range of Continental viewpoints. The authors include some of the most prominent European and European-oriented philosophers and political thinkers of our day. Two sections out of four focus on the debate between prescriptive and descriptive types of political thinking. On the prescriptive or normative side, Karl-Otto Apel, Robert Paul Wolff, Robert Spaemann, Hans Jonas, and Jean-Francois Lyotard discuss current forms of legitimating political life via some (...) ultimate grounding. On the descriptive or phenomenological side, Bernhard Waldenfels, Michel Henry, William J. Richardson, Jürgen Link, and Vincent Descombes argue that an understanding of praxis is always implied as one reaches insights into the life-world; there is no need to either construe or set normative standards for action. The remaining two sections deal with transcendental and institutional types of political philosophy, respectively. Manfred Riedel, Stanley Rosen, Thomas Seebohm, and Ludwig Siep develop Kant’s search for “a priori” conditions in the public realm; explicitly or implicitly, they confront the ancient Greek with the modern Enlightenment conceptions of life in public. Lastly, Agnes Heller, Alain Touraine, Reinhart Koselleck, and Bertram Schefold put to work many ways of looking at the life of our institutions. (shrink)

Advances in technologies and biomedical informatics have expanded capacity to generate and share biomedical data. With a lens on genomic data, we present a typology characterizing the data-sharing landscape in biomedical research to advance understanding of the key stakeholders and existing data-sharing practices. The typology highlights the diversity of data-sharing efforts and facilitators and reveals how novel data-sharing efforts are challenging existing norms regarding the role of individuals whom the data describe.

Physicists regularly invoke universal laws, such as those of motion and electromagnetism, to explain events. Biological and medical scientists have no such laws. How then do they acquire a reliable body of knowledge about biological organisms and human disease? One way is by repeatedly returning to, manipulating, observing, interpreting, and reinterpreting certain subjects—such as flies, mice, worms, or microbes—or, as they are known in biology, “model systems.” Across the natural and social sciences, other disciplinary fields have developed canonical examples that (...) have played a role comparable to that of biology’s model systems, serving not only as points of reference and illustrations of general principles or values but also as sites of continued investigation and reinterpretation. The essays in this collection assess the scope and function of model objects in domains as diverse as biology, geology, and history, attending to differences between fields as well as to epistemological commonalities. Contributors examine the role of the fruit fly Drosophila and nematode worms in biology, troops of baboons in primatology, box and digital simulations of the movement of the earth’s crust in geology, and meteorological models in climatology. They analyze the intensive study of the prisoner’s dilemma in game theory, ritual in anthropology, the individual case in psychoanalytic research, and Athenian democracy in political theory. The contributors illuminate the processes through which particular organisms, cases, materials, or narratives become foundational to their fields, and they examine how these foundational exemplars—from the fruit fly to Freud’s Dora—shape the knowledge produced within their disciplines. Contributors Rachel A. Ankeny Angela N. H. Creager Amy Dahan Dalmedico John Forrester Clifford Geertz Carlo Ginzburg E. Jane Albert Hubbard Elizabeth Lunbeck Mary S. Morgan Josiah Ober Naomi Oreskes Susan Sperling Marcel Weber M. Norton Wise. (shrink)

This volume presents the first Italian translation with commentary of the Doric Pseudo-Pythagorean texts, which are ascribed to Archytas and Brontinus and deal with metaphysical, logical, and epistemological questions. These texts probably date from the 1st century BCE and are the product of a re-emerging dogmatic interpretation of Plato's dialogues.

International research, sponsored by for-profit companies, is regularly criticised as unethical on the grounds that it exploits research subjects in developing countries. Many commentators agree that exploitation occurs when the benefits of cooperative activity are unfairly distributed between the parties. To determine whether international research is exploitative we therefore need an account of fair distribution. Procedural accounts of fair bargaining have been popular solutions to this problem, but I argue that they are insufficient to protect against exploitation. I argue instead (...) that a maximin principle of fair distribution provides a more compelling normative account of fairness in relationships characterised by extreme vulnerability and inequality of bargaining potential between the parties. A global tax on international research would provide a mechanism for implementing the maximin account of fair benefits. This model has the capacity to ensure fair benefits and thereby prevent exploitation in international research. (shrink)

Aristotle is said to have held that any kind of actual infinity is impossible. I argue that he was a finitist (or "potentialist") about _magnitude_, but not about _plurality_. He did not deny that there are, or can be, infinitely many things in actuality. If this is right, then it has implications for Aristotle's views about the metaphysics of parts and points.

Public-private partnerships are established to specifically harness the potential of Big Data in healthcare and can include partners working across the data chain—producing health data, analysing data, using research results or creating value from data. This domain paper will illustrate the challenges that arise when partners from the public and private sector collaborate to share, analyse and use biomedical Big Data. We discuss three specific challenges for PPPs: working within the social licence, public antipathy to the commercialisation of public sector (...) health data, and questions of ownership, both of the data and any resulting intellectual property or products. As a specific example we consider the case of the UK National Health Service providing patient data to Google’s DeepMind AI program to develop a diagnostic app for kidney disease. This article is an application of the framework presented in this issue of ABR. Please refer to that article for more information on how this framework is to be used, including a full explanation of the key values involved and the balancing approach used in the case study at the end. We use four specific values to help analysis these issues: public benefit, stewardship, transparency and engagement. We demonstrate how the Deliberative Framework can support ethical governance of PPPs involving biomedical big data. (shrink)

There is an alleged tension between undue inducement and exploitation in research trials. This paper considers claims that increasing the benefits to research subjects enrolled in international, externally-sponsored clinical trials should be avoided on the grounds that it may result in the undue inducement of research subjects. This article contributes to the debate about exploitation versus undue inducement by introducing an analysis of the available empirical research into research participants' motivations and the influence of payments on research subjects' behaviour and (...) risk assessment. Admittedly, the available research in this field is limited, but the research that has been conducted suggests that financial rewards do not distort research subjects' behaviour or blind them to the risks involved with research. Therefore, I conclude that research sponsors should prioritise the prevention of exploitation in international research by providing greater benefits to research participants. (edited). (shrink)

This paper takes as its point of departure recent research into the possibility that human beings can perceive single photons. In order to appreciate what quantum perception may entail, we first explore several of the leading interpretations of quantum mechanics, then consider an alternative view based on the ontological phenomenology of Maurice Merleau-Ponty and Martin Heidegger. Next, the philosophical analysis is brought into sharper focus by employing a perceptual model, the Necker cube, augmented by the topology of the Klein bottle. (...) This paves the way for addressing in greater depth the paper’s central question: Just what would it take to observe the quantum reality of the photon? In formulating an answer, we examine the nature of scientific objectivity itself, along with the paradoxical properties of light. The conclusion reached is that quantum perception requires a new kind of observation, one in which the observer of the photon adopts a concretely self-reflexive observational posture that brings her into close ontological relationship with the observed. (shrink)

ABSTRACT Rosalind Franklin is best known for her informative X-ray diffraction patterns of DNA that provided vital clues for James Watson and Francis Crick's double-stranded helical model. Her scientific career did not end when she left the DNA work at King's College, however. In 1953 Franklin moved to J. D. Bernal's crystallography laboratory at Birkbeck College, where she shifted her focus to the three-dimensional structure of viruses, obtaining diffraction patterns of Tobacco mosaic virus (TMV) of unprecedented detail and clarity. During (...) the next five years, while making significant headway on the structural determination of TMV, Franklin maintained an active correspondence with both Watson and Crick, who were also studying aspects of virus structure. Developments in TMV research during the 1950s illustrate the connections in the emerging field of molecular biology between structural studies of nucleic acids and of proteins and viruses. They also reveal how the protagonists of the “race for the double helix” continued to interact personally and professionally during the years when Watson and Crick's model for the double-helical structure of DNA was debated and confirmed. (shrink)

Bodily experience in dreams should be considered illusory to the extent that they cannot be satisfactorily explained or fruitfully investigated by appealing to brain activity alone; rather, to wholly understand the unique phenomenology of embodied selfhood in dreams, one must understand how the brain processes real-body inputs to produce the phenomenology of embodied selfhood in dreams, and why the brain responds the way it does to external stimuli during sleep.

It is shown that all spherically symmetric distributions of prematter in the framework of general relativity are static. These results provide a justification for the models of elementary particles proposed previously.

The regulation of drugs presents a challenge for liberalism: how can punishing a person for an action that harms only himself or herself be justified? For public policy a related difficulty is to justify the differential treatment of drugs and alcohol. Philosophical arguments suggest that current regulations are unjustified, and that some currently illegal drugs should be treated no more harshly than alcohol. However, such arguments make little or no impact in public policy discussions. This generates a further problem: to (...) understand the different perspectives of philosophical reasoning and public policy so that philosophical arguments can have a greater role in public policy debates. (shrink)

Social capital has as its key element the value of social relationships to generate positive outcomes, both for the key parties involved and for wider society. Some authors have noted that social capital nevertheless has a dark side. There is a moral element to such a conceptualisation, yet there is scarce discussion of ethics within the social capital literature. In this paper ethical theory is applied to four traditions or approaches to economic social capital: neo-capitalism; network/reputation; neo-Tocquevellian; and development. Each (...) is considered in detail and subject to ethical analysis by the application of utilitarianism, Kantianism, justice and rights, and ethic of care. Accordingly, the assumption that social capital is either value-neutral or a force for good is critiqued, and a framework for understanding social capital from an ethics perspective is presented. (shrink)

When the Toxic Substances Control Act was passed by the US Congress in 1976, its advocates pointed to new generation of genotoxicity tests as a way to systematically screen chemicals for carcinogenicity. However, in the end, TSCA did not require any new testing of commercial chemicals, including these rapid laboratory screens. In addition, although the Environmental Protection Agency was to make public data about the health effects of industrial chemicals, companies routinely used the agency’s obligation to protect confidential business information (...) to prevent such disclosures. This paper traces the contested history of TSCA and its provisions for testing, from the circulation of the first draft bill in the Nixon administration through the debates over its implementation, which stretched into the Reagan administration. The paucity of publicly available health and environmental data concerning chemicals, I argue, was a by-product of the law and its execution, leading to a situation of institutionalized ignorance, the underside of regulatory knowledge. (shrink)

On Zeno Beach there are infinitely many grains of sand, each half the size of the last. Supposing Aristotle denied the possibility of Zeno Beach, did he have a good argument for the denial? Three arguments, each of ancient origin, are examined: the beach would be infinitely large; the beach would be impossible to walk across; the beach would contain a part equal to the whole, whereas parts must be lesser. It is attempted to show that none of these arguments (...) was Aristotle’s. Indeed, perhaps Aristotle’s finitism applied to magnitude only, not plurality. (shrink)

Biotechnology might contribute to solving food safety and security challenges. However, gene technology has been under public scrutiny, linked to the framing of the media and public discourse. The study aims to investigate people’s perceptions and acceptance of food biotechnology with focus on transgenic genetic modification versus genome editing. An online experiment was conducted with participants from the United Kingdom and Switzerland. The participants were presented with the topic of food biotechnology and more specifically with experimentally varied vignettes on transgenic (...) and genetic modification and genome editing. The results suggest that participants from both countries express higher levels of acceptance for genome editing compared to transgenic genetic modification. The general and personal acceptance of these technologies depend largely on whether the participants believe the application is beneficial, how they perceive scientific uncertainty, and the country they reside in. Our findings suggest that future communication about gene technology should focus more on discussing trade-offs between using an agricultural technologies and tangible and relevant benefits, instead of a unidimensional focus on risk and safety. (shrink)

Aristotle offers several arguments in Physics viii.8 for his thesis that, when something moves back and forth, it does not undergo a single motion. These arguments occur against the background of a sophisticated theory, expounded in Physics v—vi, of the basic structure of motions and of other continuous entities such as times and magnitudes. The arguments in Physics viii.8 stand in a complex relation to that theory. On the one hand, Aristotle evidently relies on the theory in a number of (...) crucial steps. Yet in other steps he seems to contradict or misapply the theory. This situation offers the occasion to examine Aristotle’s views about some fundamentals in the metaphysics of motion, while also raising questions about the unity of the text which has come down to us as the Physics. (shrink)

Concerns about exploitation pervade the literature on commercial cross-border reproductive care, particularly egg selling and surrogacy. But what constitutes exploitation, and what moral weight does it have? I consider the relationship between vulnerability, limited choice, consent, and mutually advantageous exploitation. To elucidate the difference between limited choice and consent, I draw on an account of relational autonomy. In the absence of a normative principle of fair distribution, it is unclear whether the providers of reproductive goods and services are treated fairly (...) in such contracts, and therefore whether they have been exploited. I finish with some pragmatic recommendations for minimizing risks and empowering egg sellers and surrogates. (shrink)