This Oxford Reader contains 140 essential readings covering the most important debates in the Western political tradition and presents samples of the major political ideologies. Issues discussed include; the role of human nature in determining social arrangements; the political significance of gender differences; the justification for the powers of the state; democracy and the rights of minorities; the tension between liberty and equality; the way in which resources ought to be distributed; and international relations. Authors range from Plato and Aristotle (...) to Martin Luther King, Michel Foucault and Isaiah Berlin. (shrink)

We propose an ideal experiment enabling the simultaneous assignment of the objective values, 0 or 1, of two incompatible properties of a system made up of two separated, non-interacting spin particles when a strict interpretation of the criterion of reality of Einstein, Podolsky and Rosen is adopted. We compare this experiment with the physical situation involving two-value observables of a system of two correlated spin-1/2 particles envisaged by Bohm; in particular, we show its inadequacy in the dual assignment at (...) issue. Finally, we discuss a number of questions of interpretation of the consistent quantum theory highlighted by our experiment. (shrink)

In The Early Modern Subject, Udo Thiel explores early modern writings spanning approximately the seventeenth century to the first half of the eighteenth century on two topics of self consciousness, the human subject’s ‘awareness or consciousness of one’s own self’, and personal identity, the human subject’s tendency to regard one’s own self as the same identical self or person that persists through time (p. 1). The aim of the book is twofold. First, to provide an account of the development of (...) self-consciousness and personal identity covering prominent French, British, and German thinkers such as Descartes, Locke, Leibniz, Wolff, and Hume, as well as their critics, their followers, and to ‘critically evaluate their contributions’ (p. 3). The second aim is to situate the contributions of these philosophers within their historical context. In this review I summarize and evaluate The Early Modern Subject. (shrink)

We single out an alternative, strict interpretation of the Einstein-Podolsky-Rosen criterion of reality, and identify the implied extensions of quantum correlations. Then we prove that the theorem of Bell, and the non-locality theorems without inequalities, fail if the new extensions are adopted. Therefore, these theorems can be interpreted as arguments against the wide interpretation of the criterion of reality rather than as a violation of locality.

Region R Question: How many objects — entities, things — are contained in R? Ignore the empty space. Our question might better be put, 'How many material objects does R contain?' Let's stipulate that A, B and C are metaphysical atoms: absolutely simple entities with no parts whatsoever besides themselves. So you don't have to worry about counting a particle's top half and bottom half as different objects. Perhaps they are 'point-particles', with no length, width or breadth. Perhaps they are (...) extended in space without possessing spatial parts (if that is possible). Never mind. We stipulate that A, B and C are perfectly simple. We also stipulate that they are connected as follows. A and B are stuck together in such a way that when a force is applied to one of them, they move together 'as a unit'. Moreover, the two of them together exhibit behavior that neither would exhibit on its own — Perhaps they emit a certain sound, or glow in the dark — whereas C is.. (shrink)

1. Professor Brandom’s paper is addressed to a methodological question: When we set out to account for the intentionality of thought and language, what resources may we exploit? Which notions may we use? Brandom is a famously ambitious theorist. Unlike his colleague, John McDowell, Brandom has long maintained that we should at least aspire to explain intentionality in non-intentional terms. This leaves it open, however, which non-intentional resources are legitimate.

This book offers a collection of essays in contemporary political philosophy from a wide range of Continental viewpoints. The authors include some of the most prominent European and European-oriented philosophers and political thinkers of our day. Two sections out of four focus on the debate between prescriptive and descriptive types of political thinking. On the prescriptive or normative side, Karl-Otto Apel, Robert Paul Wolff, Robert Spaemann, Hans Jonas, and Jean-Francois Lyotard discuss current forms of legitimating political life via some (...) ultimate grounding. On the descriptive or phenomenological side, Bernhard Waldenfels, Michel Henry, William J. Richardson, Jürgen Link, and Vincent Descombes argue that an understanding of praxis is always implied as one reaches insights into the life-world; there is no need to either construe or set normative standards for action. The remaining two sections deal with transcendental and institutional types of political philosophy, respectively. Manfred Riedel, Stanley Rosen, Thomas Seebohm, and Ludwig Siep develop Kant’s search for “a priori” conditions in the public realm; explicitly or implicitly, they confront the ancient Greek with the modern Enlightenment conceptions of life in public. Lastly, Agnes Heller, Alain Touraine, Reinhart Koselleck, and Bertram Schefold put to work many ways of looking at the life of our institutions. (shrink)

Advances in technologies and biomedical informatics have expanded capacity to generate and share biomedical data. With a lens on genomic data, we present a typology characterizing the data-sharing landscape in biomedical research to advance understanding of the key stakeholders and existing data-sharing practices. The typology highlights the diversity of data-sharing efforts and facilitators and reveals how novel data-sharing efforts are challenging existing norms regarding the role of individuals whom the data describe.

Physicists regularly invoke universal laws, such as those of motion and electromagnetism, to explain events. Biological and medical scientists have no such laws. How then do they acquire a reliable body of knowledge about biological organisms and human disease? One way is by repeatedly returning to, manipulating, observing, interpreting, and reinterpreting certain subjects—such as flies, mice, worms, or microbes—or, as they are known in biology, “model systems.” Across the natural and social sciences, other disciplinary fields have developed canonical examples that (...) have played a role comparable to that of biology’s model systems, serving not only as points of reference and illustrations of general principles or values but also as sites of continued investigation and reinterpretation. The essays in this collection assess the scope and function of model objects in domains as diverse as biology, geology, and history, attending to differences between fields as well as to epistemological commonalities. Contributors examine the role of the fruit fly Drosophila and nematode worms in biology, troops of baboons in primatology, box and digital simulations of the movement of the earth’s crust in geology, and meteorological models in climatology. They analyze the intensive study of the prisoner’s dilemma in game theory, ritual in anthropology, the individual case in psychoanalytic research, and Athenian democracy in political theory. The contributors illuminate the processes through which particular organisms, cases, materials, or narratives become foundational to their fields, and they examine how these foundational exemplars—from the fruit fly to Freud’s Dora—shape the knowledge produced within their disciplines. Contributors Rachel A. Ankeny Angela N. H. Creager Amy Dahan Dalmedico John Forrester Clifford Geertz Carlo Ginzburg E. Jane Albert Hubbard Elizabeth Lunbeck Mary S. Morgan Josiah Ober Naomi Oreskes Susan Sperling Marcel Weber M. Norton Wise. (shrink)

International research, sponsored by for-profit companies, is regularly criticised as unethical on the grounds that it exploits research subjects in developing countries. Many commentators agree that exploitation occurs when the benefits of cooperative activity are unfairly distributed between the parties. To determine whether international research is exploitative we therefore need an account of fair distribution. Procedural accounts of fair bargaining have been popular solutions to this problem, but I argue that they are insufficient to protect against exploitation. I argue instead (...) that a maximin principle of fair distribution provides a more compelling normative account of fairness in relationships characterised by extreme vulnerability and inequality of bargaining potential between the parties. A global tax on international research would provide a mechanism for implementing the maximin account of fair benefits. This model has the capacity to ensure fair benefits and thereby prevent exploitation in international research. (shrink)

Public-private partnerships are established to specifically harness the potential of Big Data in healthcare and can include partners working across the data chain—producing health data, analysing data, using research results or creating value from data. This domain paper will illustrate the challenges that arise when partners from the public and private sector collaborate to share, analyse and use biomedical Big Data. We discuss three specific challenges for PPPs: working within the social licence, public antipathy to the commercialisation of public sector (...) health data, and questions of ownership, both of the data and any resulting intellectual property or products. As a specific example we consider the case of the UK National Health Service providing patient data to Google’s DeepMind AI program to develop a diagnostic app for kidney disease. This article is an application of the framework presented in this issue of ABR. Please refer to that article for more information on how this framework is to be used, including a full explanation of the key values involved and the balancing approach used in the case study at the end. We use four specific values to help analysis these issues: public benefit, stewardship, transparency and engagement. We demonstrate how the Deliberative Framework can support ethical governance of PPPs involving biomedical big data. (shrink)

There is an alleged tension between undue inducement and exploitation in research trials. This paper considers claims that increasing the benefits to research subjects enrolled in international, externally-sponsored clinical trials should be avoided on the grounds that it may result in the undue inducement of research subjects. This article contributes to the debate about exploitation versus undue inducement by introducing an analysis of the available empirical research into research participants' motivations and the influence of payments on research subjects' behaviour and (...) risk assessment. Admittedly, the available research in this field is limited, but the research that has been conducted suggests that financial rewards do not distort research subjects' behaviour or blind them to the risks involved with research. Therefore, I conclude that research sponsors should prioritise the prevention of exploitation in international research by providing greater benefits to research participants. (edited). (shrink)

The question of when people may impose risks on each other is of fundamental moral importance. Forms of “quantified risk assessment,” especially risk cost-benefit analysis, provide one powerful approach to providing a systematic answer. It is also well known that such techniques can show that existing resources could be used more effectively to reduce risk overall. Thus it is often argued that some current practices are irrational. On the other hand critics of quantified risk assessment argue that it cannot adequately (...) capture all relevant features, such as “societal concern” and so should be abandoned. In this paper I argue that current forms of quantified risk assessment are inadequate, and in themselves, therefore, insufficient to demonstrate that current practices are irrational. In particular, I will argue that insufficient attention has been given to the cause of a hazard, which needs to be treated as a primary variable in its own right. However rather than reject quantified risk assessment I wish to supplement it by proposing a framework to make explicit the role causation plays in the understanding of risk, and how it interacts with factors which influence perception of risks and other attitudes to risk control. Once an improved description of risk perception is available it will become possible to have a more informed debate about the normative question: how safety should be regulated. (shrink)

We investigate properties of propositional modal logic over the classof finite structures. In particular, we show that certain knownpreservation theorems remain true over this class. We prove that aclass of finite models is defined by a first-order sentence and closedunder bisimulations if and only if it is definable by a modal formula.We also prove that a class of finite models defined by a modal formulais closed under extensions if and only if it is defined by a -modal formula.

This paper examines the US Atomic Energy Commission’s radioisotope distribution program, established in 1946, which employed the uranium piles built for the wartime bomb project to produce specific radioisotopes for use in scientific investigation and medical therapy. As soon as the program was announced, requests from researchers began pouring into the Commission’s office. During the first year of the program alone over 1000 radioisotope shipments were sent out. The numerous requests that came from scientists outside the United States, however, sparked (...) a political debate about whether the Commission should or even could export radioisotopes. This controversy manifested the tension between the aims of the Marshall Plan and growing US national security concerns after World War II. Proponents of international circulation of radioisotopes emphasized the political and scientific value of collaborating with European scientists, especially biomedical researchers. In the end, radioisotopes were shipped from the Commission’s Oak Ridge facility to many laboratories in England and continental Europe, where they were used in biochemical research on animals, plants, and microbes. However, the issue of radioisotope export continued to draw political fire in the United States, even after the establishment of national atomic energy facilities elsewhere. (shrink)

The experience of skilled action occurs in dreams if we take dream reports at face value. However, what these reports indicate requires nuanced analysis. It is uncertain what it means to perform any action in a dream whatsoever. If skilled actions do occur in dreams, this has important implications for both theory of action and theory of dreaming. Here, it is argued that since some dreams generate a convincing, hallucinated world where we have virtual bodies that interact with virtual objects, (...) there is a sense in which we can perform virtual actions. Further, we can also perform skilfully, although not all apparent skilful performance is as it seems. Since the dream world is generated by the dreamer’s own mind, it can be difficult to determine whether the dream world simply allows goals to be achieved without the abilities that would be required in a similar waking scenario. Because of this, individual dream reports alone are insufficient to determine what skills are demonstrated in a particular dream. However, taken with evidence from REM sleep behaviour disorder, incompetent dreams, lucid dreams and motor-skill practise, it is likely that skilled virtual dream performance at times involves both opportunity for virtual behaviour and the display of competence. Evidence from cognitive science suggests that dreamers can also lose competence through forgetting and other cognitive incapacities but, more surprisingly, it is possible to gain abilities in a robust sense, consistent with the idea that some dreams, at least, are virtual realities rather than imagination. (shrink)

Bodily experience in dreams should be considered illusory to the extent that they cannot be satisfactorily explained or fruitfully investigated by appealing to brain activity alone; rather, to wholly understand the unique phenomenology of embodied selfhood in dreams, one must understand how the brain processes real-body inputs to produce the phenomenology of embodied selfhood in dreams, and why the brain responds the way it does to external stimuli during sleep.

It is shown that all spherically symmetric distributions of prematter in the framework of general relativity are static. These results provide a justification for the models of elementary particles proposed previously.

The recent historiography of molecular biology features key technologies, instruments and materials, which offer a different view of the field and its turning points than preceding intellectual and institutional histories. Radioisotopes, in this vein, became essential tools in postwar life science research, including molecular biology, and are here analyzed through their use in experiments on bacteriophage. Isotopes were especially well suited for studying the dynamics of chemical transformation over time, through metabolic pathways or life cycles. Scientists labeled phage with phosphorus-32 (...) in order to trace the transfer of genetic material between parent and progeny in virus reproduction. Initial studies of this type did not resolve the mechanism of generational transfer but unexpectedly gave rise to a new style of molecular radiobiology based on the inactivation of phage by the radioactive decay of incorporated phosphorus-32. These ‘suicide experiments’, a preoccupation of phage researchers in the mid-1950s, reveal how molecular biologists interacted with the traditions and practices of radiation geneticists as well as those of biochemists as they were seeking to demarcate a new field. The routine use of radiolabels to visualize nucleic acids emerged as an enduring feature of molecular biological experimentation. (shrink)

Over the past several decades, geneticists have succeeded in identifying the genetic mutations associated with disease. New strategies for treatment, including gene transfer and gene therapy, are under development. Although genetic science has been welcomed for its potential to predict and treat disease, interventions may become ethically objectionable if they threaten to alter characteristics that are distinctively human. Before we can determine whether or not a genetic technique carries this risk, we must clarify what it means to be “human”. This (...) paper inquires how “humanness” has been defined within various academic fields. The views of several legal theoreists, scientists, bioethicists, psychologists, philosophers and anthropologists whose works seem to best reflect how “humanness” is understood in their respective fields of study are considered. Our survey attempts to chart a path for a more detailed study on the meaning of “humanness” in the future. (shrink)

The regulation of drugs presents a challenge for liberalism: how can punishing a person for an action that harms only himself or herself be justified? For public policy a related difficulty is to justify the differential treatment of drugs and alcohol. Philosophical arguments suggest that current regulations are unjustified, and that some currently illegal drugs should be treated no more harshly than alcohol. However, such arguments make little or no impact in public policy discussions. This generates a further problem: to (...) understand the different perspectives of philosophical reasoning and public policy so that philosophical arguments can have a greater role in public policy debates. (shrink)

From ancient Greece to 19th-century America, this collection traces the history of civilization through the seminal works of its most influential thinkers ...

Social capital has as its key element the value of social relationships to generate positive outcomes, both for the key parties involved and for wider society. Some authors have noted that social capital nevertheless has a dark side. There is a moral element to such a conceptualisation, yet there is scarce discussion of ethics within the social capital literature. In this paper ethical theory is applied to four traditions or approaches to economic social capital: neo-capitalism; network/reputation; neo-Tocquevellian; and development. Each (...) is considered in detail and subject to ethical analysis by the application of utilitarianism, Kantianism, justice and rights, and ethic of care. Accordingly, the assumption that social capital is either value-neutral or a force for good is critiqued, and a framework for understanding social capital from an ethics perspective is presented. (shrink)

Karl Marx (1818-1883) is best known not as a philosopher but as a revolutionary communist, whose works inspired the foundation of many communist regimes in the twentieth century. It is hard to think of many who have had as much influence in the creation of the modern world. Trained as a philosopher, Marx turned away from philosophy in his mid-twenties, towards economics and politics. However, in addition to his overtly philosophical early work, his later writings have many points of contact (...) with contemporary philosophical debates, especially in the philosophy of history and the social sciences, and in moral and political philosophy. Historical materialism — Marx's theory of history — is centered around the idea that forms of society rise and fall as they further and then impede the development of human productive power. Marx sees the historical process as proceeding through a necessary series of modes of production, culminating in communism. Marx's economic analysis of capitalism is based on his version of the labour theory of value, and includes the analysis of capitalist profit as the extraction of surplus value from the exploited proletariat. The analysis of history and economics come together in Marx's prediction of the inevitable economic breakdown of capitalism, to be replaced by communism. However Marx refused to speculate in detail about the nature of communism, arguing that it would arise through historical processes, and was not the realisation of a pre-determined moral ideal. (shrink)

The book includes many seminal articles by film scholars such as Christian Metz, Jean-Louis Baudry, Stephen Heath, Peter Wollen, Laura Mulvey, and Noel Burch, and by the era's leading cultural thinkers as well: Roland Barthes, Julia ...