In the life of any species, extinction is the final evolutionary process. It is a common one at present, as the world is entering a major extinction crisis. The pattern of extinction and threat is very non-random, with some taxa being more vulnerable than others. Explaining why some taxa are affected and some escape is a major goal of conservation biology. More ambitiously, a predictive model could, in principle, be built by integrating comparable studies of past and present extinctions. We (...) review progress towards both explanatory and predictive frameworks, comparing correlates of extinction in different groups at different times. Progress towards explanatory models for the current crisis is promising, at least in some well-studied taxa, but the development of a truly predictive model is hampered by the formidable difficulties of integrating studies of present and past extinctions. BioEssays 22:1123–1133, 2000. © 2000 John Wiley & Sons, Inc. (shrink)

The theme of the third annual Spring workshop of the HUPO-PSI was proteomics and beyond and its underlying goal was to reach beyond the boundaries of the proteomics community to interact with groups working on the similar issues of developing interchange standards and minimal reporting requirements. Significant developments in many of the HUPO-PSI XML interchange formats, minimal reporting requirements and accompanying controlled vocabularies were reported, with many of these now feeding into the broader efforts of the Functional Genomics Experiment data (...) model and Functional Genomics Ontology ontologies. (shrink)

Some argue the common practice of inferring multiple processes or systems from a dissociation is flawed. One proposed solution is state-trace analysis, which involves plotting, across two or more conditions of interest, performance measured by either two dependent variables, or two conditions of the same dependent measure. The resulting analysis is considered to provide evidence that either a single process underlies performance or there is evidence for more than one process. This article reports simulations using the simple recurrent network in (...) which changes to the learning rate produced state-trace plots with multiple functions. We also report simulations using a single-layer error-correcting network that generate plots with a single function. We argue that the presence of different functions on a state-trace plot does not necessarily support a dual-system account, at least as typically defined ; it can also indicate variation in a single parameter within theories generally considered to be single-system accounts. (shrink)

The U.S. National Institute of Allergies and Infectious Diseases and the National Institute of Mental Health have a new research priority: inclusion of terminally ill persons living with HIV in HIV cure-related research. For example, the Last Gift is a clinical research study at the University of California San Diego for PLWHIV who have a terminal illness, with a prognosis of less than 6 months. As end-of-life HIV cure research is relatively new, the scientific community has a timely opportunity to (...) examine the related ethical challenges. Following an extensive review of the EOL and HIV cure research ethics literature, combined with deliberation from various stakeholders and our experience with the Last Gift study to date, we outline considerations to ensure that such research with terminally ill PLWHIV remains ethical, focusing on five topics: 1) protecting autonomy through informed consent, 2) avoiding exploitation and fostering altruism, 3) maintaining a favorable benefits/risks balance, 4) safeguarding against vulnerability through patient-participant centeredness, and 5) ensuring the acceptance of next-of-kin/loved ones and community stakeholders. EOL HIV cure-related research can be performed ethically and effectively by anticipating key issues that may arise. While not unique to the fields of EOL or HIV cure-related research, the considerations highlighted can help us support a new research approach. We must honor the lives of PLWHIV whose involvement in research can provide the knowledge needed to achieve the dream of making HIV infection curable. (shrink)

The ArgumentIt is often observed by historians of postwar American art that painters and sculptors of the 1960s sought a more mechanized “look” for their art. I argue that the changes reflected in the art have their source in a deeper shift – a shift at the level of production, expressed in new studio practices as well as in the space of the artworks themselves.In the period immediately before, during, and after World War II, the dominant topos of the American (...) artist was that of a solitary genius, alone in his studio, sole witness to the miraculous creation of his art. I demonstrate that artists of the 1960s, against this backdrop of heroic modernism, engaged in a different rhetoric and practice, one based on the models of industry and business. The studio of Andy Warhol, named the “Factory,” is viewed as apodictic of this great change, with its rudimentary assembly line and highly social mode of production.The change in practice instantiated in Warhol's Factory is significant in and of itself, but I argue further that it expressed itself in the “place of knowledge” – the space within Warhol's paintings and objects, and the newly social space in which they signify. The context for that signification thus becomes crucial to our understanding of the “Warhol phenomenon” celebrated in popular and arthistorical texts. The ambivalencies embedded in Warhol's Factory, where the artist's role oscillated between manager and proletarian worker, are seen as a function of their context. Conflicting signals are also broadcast by the works of art, which speak in the dialect of mass production with the accent of the irreplaceably unique. (shrink)

Are artists, designers and musicians inventors? Or does the invention originate from scientific discovery alone? Ecologies of Invention is the first collection of essays that brings together writers and scholars of international standing from the University of Sydney and beyond to examine assumptions underlying notions of inventiveness. The writers explain how inventiveness borne out of aesthetic ambitions is impacting on and changing our culture and society. Ecologies of Invention describes the articulation of inventive capacities across disciplines and across multiple scales, (...) from personal capacities to the social, spatial and network configurations that drive people to produce inventions. The book poses new questions for scholars, artists, architects, designers, historians, engineers, scientists, lawyers and economists about the nature, origins and processes of invention. 'This is a challenging book which confronts traditional thinking around creativity and inventiveness and raises issues that need serious debate'. Barry Jones AO. (shrink)

As Ruben notes, the macrostrategy can allow that the distinction may also be drawn at some micro level, but it insists that descent to the micro level is ...

Analysis of Competing Hypotheses (ACH) promises a relatively objective and tractable methodology for ranking the plausibility of competing hypotheses. Unlike Bayesianism, it is computationally modest. Unlike explanationism, it appeals to minimally subjective judgments about relations between hypotheses and evidence. Yet the canonical procedures for ACH allow a certain kind of instability in applications of the methodology, by virtue of supporting competing rankings despite common evidential bases and diagnosticity assessments. This instability should motivate advocates of ACH to focus their efforts toward (...) creating structured methods for individuating items of evidence. (shrink)

This book is for anyone interested in how to build a teacher education program utilizing the arts as one central modality for teaching and learning or for those interested in building some of their program along these lines. Throughout the book you will find reference to the intersection of ethics, aesthetics, and teaching. We provide an integrated program devoted to good learning and the good society. In the book we discuss how the program came to be and the underlying educational (...) thinking that informs the whole program. This section of the book is invaluable for understanding how the reader can build her/his own arts approach to teacher education. The central section of the book is devoted to the specific coursework of the program. Each author describes in detail how she/he leverages aesthetics and art to expand the possibilities of learning and teaching (including a chapter focused on the core competency course, Teaching, Imagination, Creativity) in language and literacy, psychology of education, science education, mathematics education, social studies education, and classroom management including many examples from our teaching. The book ends with a focus group discussion about the program by former students. (shrink)

The notion of folk‐psychology as a primitive speculative theory of the mental is called into question. There is cause to believe that folk‐psychology has more in common with a naive physics than with early speculative physical theorising. The distinction between these is elaborated. The conclusion drawn is that commonsense ascription of psychological content, though not a suitable finishing point for cognitive science, should still provide a more reliable source of data than some contemporary theorists are willing to admit.

Some regularities enjoy only an attenuated existence in a body of training data. These are regularities whose statistical visibility depends on some systematic recoding of the data. The space of possible recodings is, however, infinitely large – it is the space of applicable Turing machines. As a result, mappings that pivot on such attenuated regularities cannot, in general, be found by brute-force search. The class of problems that present such mappings we call the class of “type-2 problems.” Type-1 problems, by (...) contrast, present tractable problems of search insofar as the relevant regularities can be found by sampling the input data as originally coded. Type-2 problems, we suggest, present neither rare nor pathological cases. They are rife in biologically realistic settings and in domains ranging from simple animat behaviors to language acquisition. Not only are such problems rife – they are standardly solved! This presents a puzzle. How, given the statistical intractability of these type-2 cases, does nature turn the trick? One answer, which we do not pursue, is to suppose that evolution gifts us with exactly the right set of recoding biases so as to reduce specific type-2 problems to type-1 mappings. Such a heavy-duty nativism is no doubt sometimes plausible. But we believe there are other, more general mechanisms also at work. Such mechanisms provide general strategies for managing problems of type-2 complexity. Several such mechanisms are investigated. At the heart of each is a fundamental ploy – namely, the maximal exploitation of states of representation already achieved by prior, simpler learning so as to reduce the amount of subsequent computational search. Such exploitation both characterizes and helps make unitary sense of a diverse range of mechanisms. These include simple incremental learning, modular connectionism, and the developmental hypothesis of “representational redescription”. In addition, the most distinctive features of human cognition – language and culture – may themselves be viewed as adaptations enabling this representation/computation trade-off to be pursued on an even grander scale. (shrink)

Connectionism and classicism, it appears, have at least this much in common: both place some notion of internal representation at the heart of a scientific study of mind. In recent years, however, a much more radical view has gained increasing popularily. This view calls into question the commitment to internal representation itself. more strikingly still, this new wave of anti-representationalism is rooted not in 'armchair' theorizing but in practical attempts to model and understand intelligent, adaptive behaviour. In this paper we (...) first present, and then critically assess, a variety of recent anti-representationalist treatments. We suggest that so far, at least, the sceptical rhetoric outpaces both evidence and argument. Some probable causes of this premature scepticism are isolated. nonetheless, the anti-representationalist challenge is shown to be both important and progressive insofar as it forces us to see beyond the bare representational/ non-represenational dichotomy and to recognize instead a rich continuum of degrees and types of represenatationality. (shrink)

Advanced biological brains are by nature open-ended opportunistic controllers. Such controllers compute, pretty much on a moment-to-moment basis, what problem-solving resources are readily available and recruit them into temporary problem-solving wholes. Neural plasticity, exaggerated in our own species, makes it possible for such resources to become factored deep into both our cognitive and physical problem-solving routines. One way to think about this is to depict the biological brain as a master of what I shall dub ‘ecological control’. Ecological control is (...) the kind of top-level control that does not micro-manage every detail, but rather encourages substantial devolvement of power and responsibility. This kind of control allows much of our skill at walking to reside in the linkages and elastic properties of muscles and tendons. And it allows much of our prowess at thought and reason to depend upon the robust and reliable operation, often in dense brain-involving loops, of a variety of non-biological problem-solving resources spread throughout our social and technological surround. Are the complex distributed systems that result in some sense ‘out of control’, beyond the reach of useful governance? I shall argue that they are not, although understanding them requires us to re-think some key ideas about control and the nature of the self. To make this case, I shall first examine some strategies for efficient, external opportunity exploiting control in simple systems. I shall then argue that many of the same lessons apply to the case of higher-level human problem-solving. (shrink)

There is growing evidence from the science of human behavior that our everyday, folk understanding of ourselves as conscious, rational, responsible agents may be mistaken. The new essays in this volume display and explore this radical claim. folk concept of the responsible agent after abandoning the image of a central executive and "decomposing" the notion of the conscious will into multiple interlocking aspects and functions.

This article discusses how research on the image-based analysis of facial images has informed this debate by demonstrating that a single representational system for facial identity and facial expression is not only computationally viable, but can simulate existing cognitive data demonstrating apparent dissociable processing of these two facial properties. It discusses the increasing number of cognitive studies that provide support for this view. Neuropsychological case studies of brain-injured patients and provide limited evidence for separate visual routes processing facial identity and (...) facial expression. It deals with neuroimaging studies addressing both facial identity and facial expression processing which shows that the fusiform gyrus contributes to the recognition of both facial properties. Research continues to reinforce the proposal that a common visual framework supports the representation of at least some aspects of facial identity and facial expression. (shrink)

Introduction : deterritorializing Deleuze -- Spectacle I : attraction-image -- History : Deleuze after dictatorship -- Space : geopolitics and the action-image -- Spectacle II : Masala-image -- Conclusion : the continuing adventures of Deleuze and world cinemas.

Markets, companies and various forms of business organizations may all (we have argued) be usefully viewed through the lens of CAS -- the theory of complex adaptive systems. In this chapter, I address one fundamental issue that confronts both the theoretician and the business manager: the nature and opportunities for control and intervention in complex adaptive regimes. The problem is obvious enough. A complex adaptive system, as we have defined it, is soft assembled and largely self-organizing. This means that it (...) is the emergent product of multiple, and often very heterogeneous, interacting factors and forces, and that the crucial interactions are not controlled and orchestrated by an overseeing executive, detailed program, or any other source of strict hierarchical control. There is thus a pressing problem -- are such systems strictly out of control and beyond the reach of useful governance? I shall argue that they are not. Such systems, though initially unfamiliar, can nonetheless be led, influenced and enabled in a variety of ways. (shrink)

Anabaptists have long been thought to have been ‘biblicists’ and shunned reading patristic literature. But a close analysis of the debates Anabaptists had with Magisterial Reformers shows that the Anabaptists developed an extensive history of baptism using church fathers. They attempted to show that adult baptism was the norm in the earliest centuries of the church and that infant baptism was the innovation away from the Bible. This debate was about who had inherited the biblical faith around baptism.

We contend that the talk of therapy, like everyday talk, is where and how people construct their understandings and ways of living. This is the fundamental insight of the social constructionist, or discursive, therapies. ‘Meaning’ is not some pre-given ‘thing’ that is communicated more or less successfully from one individual to another. Rather, ‘meanings’ are negotiated or constructed in the process of communication until each party is clear that they have a grasp of what they are ‘talking about’. Similarly, ‘meanings’ (...) are not universal, nor necessarily arranged in a given ethical hierarchy, with some absolutely superior to others: ‘meanings’ are local and accountable in their locality. Yet, meanings, and actions following from them, are central to the conversations of therapy. In our view, the social constructionist or discursive therapies point to enhanced possibilities for collaborative and relevant conversations with clients. In this article we summarize themes common to contemporary discursive approaches to therapy. (shrink)

In his new commentary, Damper re-emphasises his claim that parity is not a generalisation problem. But when proper account is taken of the arguments he puts forward, we find that the proposed conclusion is not the only one that can be drawn.

Much work in economics, the social sciences, and elsewhere takes as it starting oint a somewhat unrealistic conception of rationality- a conception that ignores or downplays both the temporal and the situated aspects of human reason. Biological reason, I shall argue, is better concieved as an iterated process of adaptive response made under extreme time pressure and exquisitely keyed to a variety of external structures and circumstances.

The risks AI presents to society are broadly understood to be manageable through ‘general calculus’, i.e., general frameworks designed to enable those involved in the development of AI to apprehend and manage risk, such as AI impact assessments, ethical frameworks, emerging international standards, and regulations. This paper elaborates how risk is apprehended and managed by a regulator, developer and cyber-security expert. It reveals that risk and risk management is dependent on mundane situated practices not encapsulated in general calculus. Situated practice (...) surfaces ‘iterable epistopics’, revealing how those involved in the development of AI know and subsequently respond to risk and uncover major challenges in their work. The ongoing discovery and elaboration of epistopics of risk in AI (a) furnishes a potential program of interdisciplinary inquiry, (b) provides AI developers with a means of apprehending risk, and (c) informs the ongoing evolution of general calculus. (shrink)

In the movie, Memento, the hero, Leonard, suffers from a form of anterograde amnesia that results in an inability to lay down new memories. Nonetheless, he sets out on a quest to find his wife’s killer, aided by the use of notes, annotated polaroids, and body tattoos. Using these resources he attempts to build up a stock of new beliefs and to thus piece together the puzzle of his wife’s death. At one point in the movie, a character exasperated by (...) Leonard’s lack of biological recall, shouts: “YOU know? What do YOU know. YOU don’t know anything. In 10 minutes time YOU won’t even know you had this conversation” Leonard, however, believes that he does, day by day, come to know new things. But only courtesy of those photos, tattoos, tricks and ploys. Who is right?These are the kinds of question addressed at length in the paper ‘The Extended Mind’. Is the mind contained in the head? Or does the notion of thought allow mental processes to inhere in extended systems of body, brain and aspects of the local environment? The answer, we claimed, was that mental states, including states of believing, could be grounded in physical traces that remained firmly outside the head. As long as a few simple conditions were met, Leonard’s notes and tattoos could indeed count as new additions to his store of long-term knowledge and dispositional belief. In the present treatment I revisit this argument, defending our strong conclusion against a variety of subsequent observations and objections. In particular, I look at objections that rely on a contrast between the intrinsic content of neural symbols and the merely derived content of external inscriptions, at objections concerning the demarcation of scientific domains via natural kinds, and at objections concerning the ultimate locus of agentive control and the nature of perception versus introspection. I also mention a possible alternative interpretation of the argument as a reductio of the very idea of the mind as an object of scientific study. This is an interesting proposal. (shrink)

What is the relation between perceptual experience and the suite of sensorimotor skills that enable us to act in the very world we perceive? The relation, according to ‘sensorimotor models’ is tight indeed. Perceptual experience, on these accounts, is enacted via skilled sensorimotor activity, and gains its content and character courtesy of our knowledge of the relations between movement and sensory stimulation. I shall argue that this formulation is too extreme, and that it fails to accommodate the substantial firewalls, dis-integrations, (...) and specialpurpose streamings that form the massed strata of human cognition. In particular, such strong sensorimotor models threaten to obscure the computationally potent insensitivity of key information-processing events to the full subtleties of embodied cycles of sensing and moving. (shrink)

Language, according to Jackendoff, is more than just an instrument of communication and cultural transmission. It is also a tool which helps us to think. It does so, he suggests, by expanding the range of our conscious contents and hence allowing processes of attention and reflection to focus on items which would not otherwise be available for scrutiny. I applaud Jackendoff s basic vision, but raise some doubts concerning the argument. In particular, I wonder what it is about public language (...) that uniquely fits it to play the functional role which Jackendoff isolates — why couldn't expression in a private inner code induce the same computational benefits? I suggest a weaker position in which the communicative role of public language moulds it into a suitably expressive resource, such that natural language emerges as the logically and technologically contingent filler of a functional role which could, in principle, be filled by other means. I also compare and contrast Jackendoff's position with some related ideas due to Daniel Dennett and others, concluding with a sketch of my own view of language as an external artifact whose computational properties complement those of the basic biological brain. (shrink)

Fodor’s theory makes thinking prior to doing. It allows for an inactive agent or pure reflector, and for agents whose actions in various ways seem to float free of their own conceptual repertoires. We show that naturally evolved creatures are not like that. In the real world, thinking is always and everywhere about doing. The point of having a brain is to guide the actions of embodied beings in a complex material world. Some of those actions are, to be sure, (...) more recondite than others. But in every case the contents of thoughts still look to depend, in some non-unique but vitally important way, on the kinds of doings they support. (shrink)

Enquiries into the possible nature and scope of innate knowledge never proceed in an empirical vaccuum. Instead, such conjectures are informed by a theory concerning probable representational form. Classical approaches to the nativism debate often assume a quasi-linguistic form of knowledge representation and deliniate a space of options accordingly. Recent connectionist theorizing posits a different kind of represenational form, and thus determines a different picture of the space of possible nativisms.

Can we really make sense of the idea (implied by Block's treatment) that there can be isolated islets of experience that are not even potentially available as fodder for a creature's conscious choices and decisions? The links between experience and the availability of information to guide conscious choice and inform reasoned action may be deeper than the considerations concerning (mere) reportability suggest.

In the original publication, funding information was missing: Andy Clark was supported by ERC Advanced Grant 692739.

Kleinberg describes a novel procedure for efficient search in a dense hyper-linked environment, such as the world wide web. The procedure exploits information implicit in the links between pages so as to identify patterns of connectivity indicative of “authorative sources”. At a more general level, the trick is to use this second-order link-structure information to rapidly and cheaply identify the knowledge-structures most likely to be relevant given a specific input. I shall argue that Kleinberg’s procedure is suggestive of a new, (...) viable, and neuroscientifically plausible solution to at least the so-called “Frame Problem” in cognitive science viz the problem of explaining global abductive inference. More accurately, I shall argue that Kleinberg’s procedure suggests a new variety of “fast and frugal heuristic” ) capable of pressing maximum utility from the vast bodies of information and associations commanded by the biological brain. The paper thus takes up the challenge laid down by Fodor ). Fodor depicts the problem of global knowledge-based reason as the point source of many paradigmatic failings of contemporary computational theories of mind. These failings, Fodor goes on to argue, cannot be remedied by any simple appeal to alternative modes of encoding and processing. I shall show, however, that connectionist models can provide for one neurologically plausible incarnation of Kleinberg’s procedure. The paper ends by noting that current commercial applications increasingly confront the kinds of challenge initially posed to biological thought and reason. (shrink)

It is widely appreciated that the difficulty of a particluar computation varies according to how the input data are presented. What is less understood is the effect of this computation/representation tradeoff within familiar learning paradigms. We argue that existing learning algoritms are often poorly equipped to solve problems involving a certain type of important and widespread regularity, which we call 'type-2' regularity. The solution in these cases is to trade achieved representation against computational search. We investigate several ways in which (...) such a trade-off may be pursued including simple incremental learning, modular connectionism, and the developmental hypothesis of 'representational redescription'. In addition, the most distinctive features of human cognition- language and culture- may themselves be viewed as adaptions enabling this representation/computation trade-off to be pursued on an even grander scale. (shrink)