The immunoglobulin molecule is a perfect template for the de novo generation of biocatalytic functions. Catalytic antibodies, or abzymes, obtained by the structural mimicking of enzyme active sites have been shown to catalyze numerous chemical reactions. Natural enzyme analogs for some of these reactions have not yet been found or possibly do not exist at all. Nowadays, the dramatic breakthrough in antibody engineering and expression technologies has promoted a considerable expansion of immunoglobulin's medical applications and is offering abzymes a unique (...) chance to become a promising source of high‐precision “catalytic vaccines.” At the same time, the discovery of natural abzymes on the background of autoimmune disease revealed their beneficial and pathogenic roles in the disease progression. Thus, the conflicting Dr. Jekyll and Mr. Hyde protective and destructive essences of catalytic antibodies should be carefully considered in the development of therapeutic abzyme applications. (shrink)

Some are attracted to the view that repeatable artworks, such as films, novels, plays, symphonies, photographs, and the like, are a particular kind of abstracta—namely, types. This view, however, is not unproblematic. One of the most serious problems it faces is the so-called "creation problem." The core idea behind this problem is that, on the one hand, it seems reasonable to accept the claims that (1) repeatable artworks are types, (2) types cannot be created, and (3) repeatable artworks are created, (...) but, on the other hand, these claims form an inconsistent triad. A popular solution to the creation problem is that (2) can be rejected because the justification for (2) is based on a false assumption—that no type can stand in causal relations. Although this solution looks promising, it can be accepted only if its proponent can refute what might be called the "paraphrasability argument." On this argument, types are not to be regarded as capable of standing in causal relations because any discourse implying the causality of types should be paraphrased into discourse that does not imply this. My aim in this essay is to show that there is good reason to consider the paraphrasability argument sound and, hence, that the foregoing solution to the creation problem fails. (shrink)

The question ‘What is a novel?’ has received scant attention in the philosophical literature. Meanwhile, this question is important. In the light of this, in this paper, I would like to address it, suggesting a potential answer. I begin by defining what I call ‘novel in the restricted sense’ – the concept that covers all novels except the so-called nonfiction novels, graphic novels, and novels in verse. Then, drawing upon Jerrold Levinson’s approach to defining ‘art’, I provide a definition of (...) the concept that covers nonfiction novels, graphic novels, and novels in verse. Finally, with the help of this definition and the definition of ‘novel in the restricted sense’, I formulate a definition of ‘novel’ simpliciter and defend it against potential objections. (shrink)

This paper presents a short analysis of the so-called ‘conservative turn’ in contemporary Russia. This ‘turn’ is examined in the context of the previous development of Russian conservatism, particularly its degradation into imitational bureaucratic conservatism in the second half of the nineteenth century. I argue that this ‘new conservatism’ in contemporary Russian politics reflects this degradation and is, in fact, a pseudo-conservatism which has no conservative core but rather an ad hoc (tactical, pseudo-historical, anti-intellectual) character. I also argue that we (...) need to revise our understanding of contemporary autocracies in light of this phenomenon, which is deeply connected to the worldwide crisis of conservatism. (shrink)

This article focuses on the general theoretical issue of realism versus constructivism in politics, with a case of the present-day Russia as the main and most telling example. We present four assertions that we are going to defend. First, we claim that in the sphere of international relations, political realism of the offensive type, after decades of more tempered USA–USSR relations, is again challenging its opponent: political constructivism. Second, political realism is winning in the sphere of domestic politics and policy (...) in the leading countries as well. Third, we touch upon theoretical issues and discuss the ontological nature of political realism in comparison with political constructivism and the kindred of the latter with normativism, legalism, constitutionalism and liberalism. Political constructivism as a concept is underestimated and rarely used. Our article explicates the concept of political constructivism, which is a novel contribution to political theory and political philosophy. Fourth, we show that political constructivism, being the most advanced achievement of political civilization compared to archaic realism, has not lost the game so far and should be upheld in its battle with the remnants of the wild political past. Sliding back to political realism would turn humankind into another degraded animal species instead of making it the pilot in continuing human progress. (shrink)

The king therefore went down to the village, since the Wise Men's rule did not permit him to spend more than a day with them, but Iarchas said to the messenger, ‘Damis too we consider worthy of the secrets here, so tell him to come, while you look after the others in the village.’ When Damis had come, the Wise Men formed their usual circle and gave Apollonius permission to put questions. So he asked what they thought the universe consisted (...) of, to which they replied, ‘Elements.’ ‘Four, do you think?’ he said. ‘Not four’, said Iarchas, ‘but five.’ ‘What could a fifth one be’, said Apollonius, ‘besides water, air, earth, and fire?’ ‘Ether’, said Iarchas, ‘which we must consider to be the origin (γένεσιν) of the gods. All that breathes air is mortal, but what breathes ether is immortal and divine.’ Next Apollonius asked which of the elements came into existence first. ‘All came together’, said the other, ‘since a living being is not born one piece at a time.’ ‘Am I to consider the universe living?’, asked Apollonius. ‘Yes, if you reason correctly’, said Iarchas, ‘since itself it gives life to everything.’ ‘Should we then call it female’, asked Apollonius, ‘or of the contrary, male sex?’ ‘Of both’, was the answer, ‘since it has intercourse with itself, and performs both the mother's and the father's role with respect to generation. It feels a desire for itself more intense than that of any two other beings, and this joins and unites it, and there is nothing unreasonable about its coalescence. And just as the action of the hands and feet in a living creature comes from mobility and the intelligence (διὰ τὸν ἐκείνου νοῦν) that causes it, so also we must suppose that, because of the intelligence of the universe (κατὰ τὸν ἐκείνου ϕοιτᾷ νοῦν), its parts accommodate themselves to everything that undergoes birth and conception. For instance, the sufferings resulting from drought arise from the mind of the universe, when justice is banished from mankind and treated with dishonor. And this being guides itself not by one hand alone but by many unseen ones that it uses; though too large to be restrained, it moves obediently and tractably.’The doctrine contained in this extract – the only passage ofThe Life of Apollonius of Tyanatreating matters of ‘cosmogony’ – could be summarized in the six following propositions. First, the universe consists of five, not four elements, the fifth being the ether, the γένεσις θεῶν. Just as mortals breathe air, gods breathe ether. Secondly, there is no ‘primordial element’; all five came into being simultaneously. Thirdly, the universe is a living being. In the fourth place, the universe is both male and female at the same time. In the fifth place, as the universe is androgynous it feels desire (ἔρως) towards itself and it is this desire that makes it whole and united. And finally, the passion of the universe for itself is governed by Intelligence (ἐκείνου νοῦς). (shrink)

Some biblical texts suggest that man consists of two parts—body and soul—whereas others seem to indicate instead three parts—body, soul, and spirit. This paper examines how the Church Fathers dealt with this apparent contradiction. It finds that although they generally favor the body-soul dichotomy, they did not see it as contradicting a trichotomous view, for “spirit” can be interpreted in a number of ways: as another term for the soul, or as the lowest imaginative part of the soul, or as (...) its highest rational part, or as the grace of the Holy Spirit. Different approaches can be found in different patristic authors depending on their theological interests and the biblical passages at issue. (shrink)

The article stresses that Georgy P. Fedotov's systematic reference to the Bible enabled him in his historical monographs to reconstruct the spiritual reality of past eras and symbolically perceive the present. Fedotov intended to know The Gospel in History, Russian religiosity, exploring it on the material of hagiographies of saints, spiritual poems, folk faith, apocrypha, and prologues. Fedotov considered the history of Russian culture in terms of a "living chain," an integral phenomenon existing due to the Holy Scriptures and Holy (...) Tradition. However, "The sacred tradition of the Church is included in the general stream of historical tradition, all complex, always muddy, human weaving truth and falsehood." Fedotov raised the question of the relationship between scientific criticism and biblical exegetics: how can we reconcile exegetics of sacred texts, which assume that the Bible is an inspired book, and historical criticism, which by its very nature cannot share such a position, being aimed at comprehending objective historical reality? He solved it convincingly practically through hermeneutic religious analysis of hagiographic monuments and spiritual verses. In his Spiritual Poems Fedotov explores folklore material compared to biblical texts, hagiographies, and apocrypha, to comprehend the peculiarity of religious "Weltanschauung" and popular orthodoxy. In spiritual verses, there was a transformation of biblical images under the influence of folk faith with pagan features. In folklore texts, Fedotov reveals how Christ, from savior and redeemer, turns into a king and dreadful judge. The image of the Mother of God merges in the popular consciousness with the image of the mother earth, suffering from people. Eschatological prophecies are based on impressions from icons, frescoes, and lubok pictures. Fedotov's historical monographs illuminate various aspects of Russian religious consciousness regarding Holy Scripture, considering dogmatic biblical exegetics and historical criticism. All the mentioned facts allow us to assert that Fedotov was the leading secular biblical scholar of the Russian diaspora. (shrink)

In this paper the questions remaining open about NP-completeness of multiplicative and Horn fragments of the Linear Logic and the Linear Logic with the weakening rule are answered.

Quantum observables can be identified with vector fields on the sphere of normalized states. Consequently, the uncertainty relations for quantum observables become geometric statements. In the Letter the familiar uncertainty relation follows from the following stronger statement: Of all parallelograms with given sides the rectangle has the largest area.

The paradoxes of the double-slit experiment with an electron are shown to originate in the implicit assumption that the electron is always located in the classical space. It is demonstrated that there exists a natural substitute for this assumption that provides a method of resolving the paradoxes.

The article is devoted to the reasoning of the „Ereignis“ phenomenon in the philosophy of M. Heidegger. It is worth to emphasize that one of the main trends in contemporary philosophy is an attempt of creation of new–non-substantial–ontology. The very specificity of such ontology lies in the fact that classical substance is replaced by the dynamical configuration of sense, which is not “purely theoretical” but “ontological” in its core. “Ontological” means, in fact, that it is impossible to separate the mode (...) of Being of phenomena from the process of thinking about them. Heidegger’s philosophy was one of the first attempts to create such ontology. It is worth to point out the three steps of the Heidegger’s studies of Being. The first, “fundamental-ontological” step is characterized primarily through the “ontological difference” between Being and entity, when the phenomenon of time represents by itself their hidden basis. During the second, “radical-ontological” period, Heidegger has already carried out his famous “turn.” In compliance with this “turn,” the truth of Being, die Lichtung, substitutes time as the “pre-ontological” basement of Being. In this case, Being itself transforms into the Event, „Ereignis“. On the third, “post-ontological” stage of studies the focal point of Heidegger’s thought is “post-ontological difference” between the Being of entity and Being itself. On this stage both Being and time are rooted in the phenomenon of „Ereignis“. The latter has been now transformed from being a “simple Event” into a “matter of fact” as the alternation of the “disclosedness” and “concealness” of Being and time. In this case, „Ereignis“ is not quasi-substantial basement of Being, time or entity but it shows itself as its “Beginning” “), when the Truth of Being is replaced by the dynamical sense configuration of the event, i.e., a “matter of fact.” Thus, Heidegger has conceptually created a new type of thnon-substantial ontology, the core of which is the phenomenon of „Ereignis“ as the dynamical singular configuration of the temporal-ontological sense of the Event itself. (shrink)

The expression ‘an instance of an artwork’ is often used in philosophical discourse about art. Yet there is no clear account of what exactly this expression means. My goal in this essay is to provide such an account. I begin by expounding and defending a particular definition of the concept of ‘an instance of an artwork’. Next, I elaborate this definition – by providing definitions of the main derivatives of the concept of ‘an instance of an artwork’, namely the concepts (...) of ‘a well-formed instance of an artwork’ and ‘a non-wellformed instance of an artwork’. Finally, I examine the relation of the foregoing definitions to the existence and identity conditions of artworks and make some additional remarks concerning these definitions. (shrink)

A geometric approach to quantum mechanics with unitary evolution and non-unitary collapse processes is developed. In this approach the Schrödinger evolution of a quantum system is a geodesic motion on the space of states of the system furnished with an appropriate Riemannian metric. The measuring device is modeled by a perturbation of the metric. The process of measurement is identified with a geodesic motion of state of the system in the perturbed metric. Under the assumption of random fluctuations of the (...) perturbed metric, the Born rule for probabilities of collapse is derived. The approach is applied to a two-level quantum system to obtain a simple geometric interpretation of quantum commutators, the uncertainty principle and Planck’s constant. In light of this, a lucid analysis of the double-slit experiment with collapse and an experiment on a pair of entangled particles is presented. (shrink)

Infinite-dimensional manifolds modelled on arbitrary Hilbert spaces of functions are considered. It is shown that changes in model rather than changes of charts within the same model make coordinate formalisms on finite and infinite-dimensional manifolds deeply similar. In this context the infinite-dimensional counterparts of simple notions such as basis, dual basis, orthogonal basis, etc. are shown to be closely related to the choice of a model. It is also shown that in this formalism a single tensor equation on an infinite-dimensional (...) manifold produces a family of functional equations on different spaces of functions. (shrink)

Composition-nominative logics are program-oriented logics. They are based on algebras of partial predicates which do not have fixed arity. The aim of this work is to present CNL as institutions. Homomorphisms of first-order CNL are introduced, satisfaction condition is proved. Relations with institutions for classical first-order logic are considered. Directions for further investigation are outlined.

My goal is to conceive how the reality would look like for hypothetical creatures that supposedly perceive on time scales much faster or much slower than that of us humans. To attain the goal, I propose modelling in two steps. At step one, we have to single out a unified parameter that sets time scale of perception. Changing substantially the value of the parameter would mean changing scale. I argue that the required parameter is duration of discrete perceptive frames, or (...) snapshots, whose sequencing constitutes perceptive process. I show that different standard durations of perceptive frames is the ground for differences in perceptive time scales of various animals. Abnormally changed duration of perceptive frames is the cause of the effect of distorted subjective time observed by humans under some conditions. Now comes step two of the modelling. By inserting some arbitrary duration of a perceptive frame, we set a hypothetical scale and thus emulate a viewpoint for virtual observation of the reality in a wider or narrower angle of embracing events in time. Like changing lenses of a microscope, viewing reality in different temporal scales makes certain features of reality manifested, others veiled. These are, in particular, features of life. If we observe an object in an inappropriate interval, we may not notice the very essence of a process it is undergoing. (shrink)

A mathematical framework that unifies the standard formalisms of special relativity and quantum mechanics is proposed. For this a Hilbert space H of functions of four variables x,t furnished with an additional indefinite inner product invariant under Poincare transformations is introduced. For a class of functions in H that are well localized in the time variable the usual formalism of non-relativistic quantum mechanics is derived. In particular, the interference in time for these functions is suppressed; a motion in H becomes (...) the usual Shrodinger evolution with t as a parameter. The relativistic invariance of the construction is proved. The usual theory of relativity on Minkowski space-time is shown to be ``isometrically and equivariantly embedded'' into H. That is, classical space-time is isometrically embedded into H, Poincare transformations have unique extensions to isomorphisms of H and the embedding commutes with Poincare transformations. (shrink)

The consensus is that repeatable artworks cannot be identified with particular material individuals. A perennial temptation is to identify them with types, broadly construed. Such identification, however, faces the so-called “Creation Problem.” This problem stems from the fact that, on the one hand, it seems reasonable to accept the claims that (1) repeatable artworks are types, (2) types cannot be created, and (3) repeatable artworks are created, but, on the other hand, these claims are mutually inconsistent. A possible solution to (...) the Creation Problem is to argue that claim (2) can be rejected because (a) the only motivation for it is that a type, being abstract, cannot stand in causal relations, but (b) this motivation is ungrounded, since types can, in fact, stand in such relations. Clearly, in order for this solution to be successful, it is necessary to substantiate the possibility of types to be causally efficacious. In this essay, I examine an attempt to do this with the help of Yablo’s principle of proportionality, which has been undertaken by Walters (2013) and, more recently, Juvshik (2018). Although the argument they advance may seem to provide strong support for the causal efficacy of types, I think it actually fails to do this. To explain why this is so, I first show that this argument commits us to the existence of widespread causal overdetermination involving types and then argue that this commitment is both epistemically and ontologically problematic. (shrink)

A considerable number of philosophers are attracted to what might be called ‘causal type-abstractionism’ – the view that photographs, symphonies, models of cars, novels, flags, and other multiply i...

Two aspects of the target article, (1) the extension of the equilibrium point theory to multi-joint movements, and (2) the consequence that the EMG pattern is not directly controlled by the central nervous system (CNS), are discussed in light of the experiments on upper trunk bending in humans. The principle component kinematic analysis and the analysis of the EMG data, obtained under microgravity and additional loading conditions, support the application of Feldman and Levin's for multi-joint pointing movement to equilibrium control (...) during upper trunk movement. (shrink)

Xenophanes claimed that God is a ball, which means that he is a perfect body. This idea is well developed in Jagannatha worship, who is a central Deity in Orissa, India. It’s a round form of Krishna, who is usually depicted in a human like form. Jagannatha, his brother Baladeva and sister Subhadra are justified as round forms because of their specific manifestation of ecstasy, that, according to aesthetical theory (rasa tattva) happened to them. Yet there are many other explanations (...) of the Jagannatha’s roundness. Round form personifies unity and diversity principle in Jagannatha worship, whose image was dear in Orissa duringlong historical period to different religious groups: Vaishnavas, Shaivaites, Jains, Buddhists and even some Muslims. Orissa also has a blending of different cultures, sub-cultures and traditions. Even now, it has 62 distinct tribal groups, that makes a largest collection of diverse tribes in a single state. As the legend goes, Jagannatha made His first appearance in the tribe of Savaras thousands of years ago. Up until now, there are cooks in the Jagannatha kitchen that are called sauviras. In worship of Jagannatha we find the model of axiological globalism, when the difference in the vision of the reality does not obscure the interior mood of wholeness, unity. (shrink)

There is widespread opinion that, notwithstanding deviations, the political life of humanity on a large scale is on the path of progress, and humans are becoming freer and more enlightened with time. I am going to contend with this opinion, namely, with a part of it telling that the prevailing mass of the people strives to achieve more freedom and enlightenment. On the opposite, freedom, individual independence, and political rights are of minor importance to the mass. The ideology of liberalism (...) in its classical form, as created by John Locke, Immanuel Kant, John Stuart Mill and others, yields to the pressure of the ideology of state paternalism. The pressure comes not only from above ; the people also welcome more paternalism. They appear not to value their individual freedom and independence, and they are inclined to give them up voluntarily to some mighty organization such as the state in exchange for care, protection and leadership. Liberalism has played an important role in the development of human civilization and the formation of the Western world, but new ideologies and political practices are pushing it out of people’s minds. For the author, as adherent of classical liberalism, this is unfortunate. However, I wish to treat this issue realistically, even if the facts conflict with my own convictions and desires. (shrink)

There is a widely shared belief in contemporary epistemology that propositional knowledge is incompatible with certain kinds of luck, most of all with so called veritic luck. A subject is veritically lucky in his or her belief that p if this belief is true not due to its foundations (for example, reasons which an agent has to believe that p) but by mere accident. The acceptance of the thesis of incompatibility of knowledge with this kind of luck led to significant (...) modifications of a popular modern epistemological tripartite analysis of propositional knowledge according to which subject knows that p if and only if he or she believes that p is true, p is actually true, and an agent’s belief that p is true is justified. In his famous paper “Is True Justified Belief Knowledge” E. Gettier demonstrated that true justified belief may not be knowledge. The core of the problem is that in the cases described by Gettier and the like an agent’s belief, though justified, is true by accident. This gave rise to a set of theories introducing additional conditions of knowledge which could exclude veritic luck. In this paper the author critically discusses main modifications of the tripartite concept of knowledge aimed at making it independent on veritic luck, and show that they are unable to solve this problem. He agrees with those who think that the very thesis of incompatibility of knowledge with veritic luck is wrong. But he disagrees that all kinds of veritic luck are compatible with knowledge: the author supposes that good veritic luck is compatible with knowledge only when it compensates some negative effect of antecedent bad epistemic luck. According to this view original Gettier examples are not cases of knowledge whereas broken-clocks case and fake-barns case are. This account allows treating many classic cases of dependence of knowledge on luck as cases of knowledge-acquirement, but in the same time it excludes the inclusion into the class of knowledge such intuitively irrelevant outcomes as lucky guess and wishful thinking. (shrink)

Within the Hebbian paradigm the mechanism for integrating cell assemblies oscillating with different frequencies remains unclear. We hypothesize that such an integration may occur in cortical “interaction foci” that unite synchronously oscillated assemblies through hard-wired connections, synthesizing the information from various functional systems of the brain.

1. On the contradictory nature of contemporary linguistic theories and how to change it for the better -- 2. A reference-based approach to describing notional words -- 3. Basic-level concepts as the neurobiological codes for memory -- 4. Elements of a sensory grammar -- 5. On the single structure of lexical meanings of nouns and verbs -- References -- Index.

Coordinate formalism on Hilbert manifolds developed in \cite{Kryukov} is reviewed. The results of \cite{Kryukov} are applied to the simpliest case of a Hilbert manifold: the abstract Hilbert space. In particular, functional transformations preserving properties of various linear operators on Hilbert spaces are found. Any generalized solution of an arbitrary linear differential equation with constant coefficients is shown to be related to a regular solution by a (functional) coordinate transformation. The results also suggest a way of using generalized functions to solve (...) nonlinear problems on Hilbert spaces. (shrink)

Newtonian and Scr{\"o}dinger dynamics can be formulated in a physically meaningful way within the same Hilbert space framework. This fact was recently used to discover an unexpected relation between classical and quantum motions that goes beyond the results provided by the Ehrenfest theorem. A formula relating the normal probability distribution and the Born rule was also found. Here the dynamical mechanism responsible for the latter formula is proposed and applied to measurements of macroscopic and microscopic systems. A relationship between the (...) classical Brownian motion and the diffusion of state on the space of states is discovered. The role of measuring devices in quantum theory is investigated in the new framework. It is shown that the so-called collapse of the wave function is not measurement specific and does not require a ``concentration" near the eigenstates of the measured observable. Instead, it is explained by the common diffusion of state over the space of states under interaction with the apparatus and the environment. This in turn provides us with a basic reason for the definite position of macroscopic bodies in space. (shrink)

Quantum observables can be identified with vector fields on the sphere of normalized states. The resulting {\it vector representation} is used in the paper to undertake a simultaneous treatment of macroscopic and microscopic bodies in quantum mechanics. Components of the velocity and acceleration of state under Schr{\"o}dinger evolution are given a clear physical interpretation. Solutions to Schr{\"o}dinger and Newton equations are shown to be related beyond the Ehrenfest results on the motion of averages. A formula relating the normal probability distribution (...) and the Born rule is found. (shrink)

The paradoxes of the EPR experiment with two particles are shown to originate in the implicit assumption that the particles are always located in the classical space. There exists a substitute for this assumption that yields a new definition of reality and offers a resolution of the paradoxes.

We give an affirmative answer to the following question: Is any Borel subset of a Cantor set C a sum of a countable number of pairwise disjoint h-homogeneous subspaces that are closed in X? It follows that every Borel set \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${X \subset {\bf R}^n}$$\end{document} can be partitioned into countably many h-homogeneous subspaces that are Gδ-sets in X.

We study uncertainty relations for a general class of canonically conjugate observables. It is known that such variables can be approached within a limiting procedure of the Pegg–Barnett type. We show that uncertainty relations for conjugate observables in terms of generalized entropies can be obtained on the base of genuine finite-dimensional consideration. Due to the Riesz theorem, there exists an inequality between norm-like functionals of two probability distributions in finite dimensions. Using a limiting procedure of the Pegg–Barnett type, we take (...) the infinite-dimensional limit right for this inequality. Hence, uncertainty relations are derived in terms of generalized entropies. In particular, the case of measurements with a finite precision is addressed. It takes into account that in any experiment an accuracy of performed measurements is always limited. (shrink)

The research identifies the amount of headline/article discrepancies in the corpora of western and Russian online articles on sensitive political topics. A quarter of the western headlines and nearly half of the Russian headlines distort the publications they introduce. Language means and manipulative strategies employed by different sides vary considerably. Extensive use of expressive language and style variation are seen as leading causes of distortions in the western corpus. The rich imagery used by the authors forms emotional implicatures that affect (...) the reader’s perception of the issue. In contrast, information substitution, subjective modality and selective citations are identified as major causes of distortions in the Russian corpus. Contributors to Russian news outlets rely on general rather than language manipulation strategies, including frequent use of logical fallacies and wrong generalizations. These techniques establish false logical sequences and wrong causative implicatures that compromise objective reporting. The underlying motives of the journalists’ creating false emotional and causative implicatures in the headlines lies beyond the scope of the study; however, it is assumed that intentional change of the information introduced by the headline could be viewed as a covert misinformation attempt. (shrink)

This article explores theoretical conditions necessary for “quantum immortality” as well as its possible practical implications. It is demonstrated that QI is a particular case of “multiverse immortality”, which is based on two main assumptions: the very large size of the universe ; and a copy-friendly theory of personal identity. It is shown that a popular objection about lowering of the world-share of an observer in the case of QI does not succeed, as the world-share decline could be compensated by (...) merging timelines for the simpler minds, and because some types of personal preferences are not dependent on such changes. Despite large uncertainty about the truth of MI, it has appreciable practical consequences for some important outcomes like suicide and aging. The article demonstrates that MI could be used to significantly increase the expected subjective probability of success of risky life extension technologies, such as cryonics, but that it makes euthanasia impractical because of the risk of eternal suffering. Euthanasia should be replaced with cryothanasia, i.e. cryopreservation after voluntary death. Another possible application of MI is as a last chance to survive a global catastrophe. MI could be considered a Plan D for reaching immortality, where Plan A consists of survival until the development of beneficial Artificial Intelligence capable of fighting aging, Plan B employs cryonics, and Plan C is digital immortality. (shrink)

The consensus is that the novel—along with painting, sculpture, and architecture—should be categorized as a non-performing art. In this essay, I argue that such categorization is misguided: In fact, there is good reason to categorize the novel as a performing art. I begin by showing that x is a performing art if the following conditions are satisfied: x is an art and to fully appreciate a work of x, it is necessary to experientially engage with a performance or a performance-like (...) object. I then demonstrate that in the case of the novel, these conditions are actually satisfied. (shrink)

Cell interdivision periods (IDP) in homogenous cell populations vary stochastically. Another aspect of probabilistic cell behavior is randomness in cell differentiation. These features are suggested to result from competing stochastic events of assembly/disassembly of the transcription pre‐initiation complex (PIC) at gene promoters. The time needed to assemble a proper PIC from different proteins, which must be numerous enough to make their combination gene specific, may be comparable to the IDP. Nascent mRNA visualization at defined genes and inferences from protein level (...) fluctuations in single cells suggest that some genes do operate in this way. The onset of mRNA production by such genes may miss the time windows provided by the cell cycle, resulting in cells differentiating into those in which the respective mRNAs are either present or absent. This creates a way to generate cell phenotype diversity in multicellular organisms. (shrink)

The article discusses the diversity of the subject field of the philosophy of war as well as the internal integrity of the discipline, united by the focus on the philosophical understanding of the phenomenon of war. The author shows the role of H. Lloyd, who influenced K. Clausewitz, H. Jomini and their followers’ interpretation of the meaning and content of the subject area of the philosophy of war. In the abundance of specific topics addressed by philosophers of this field, the (...) following topics should be noted: the issue of victory and defeat and their interpretation as well as the issue of historical memory. This problem is projected on contemporaneity and reflects the deep connection between peace and war, the dialectic of their relations. The interpretation of certain military and political events is of real interest in the light of the processes of distortion of historical events that have radically affected the course of history. An analysis of the motives and causes of this process is supposes to reconstruct an objective picture of relations between the subjects of international relations in various periods of history. The author finds answers in already existing concepts that have been developed in our time. It is important to mention the project of the French philosopher Charles Renouvier, who put forward the concept of “uchronia,” which became the starting point for the consideration of historical events in the “subjunctive mood.” This genre of historiosophical fantasy was picked up by famous followers – by the former President of France V. Giscard d’Estaing and others. The article provides eyewitness accounts of historical events (in particular, the campaign of Napoleon in Russia) that are historical facts and help to understand the true state of things. The article demonstrates that the philosophical study of the problem of war is important for understanding the origins and essence of relations arising from the transition between peaceful and military states. (shrink)

The article is related to the revealing of the intent of Hegel’s “Science of Logic”. As authors take it, there is an attempt to imagine the fundamental level of reasoning, where there is no opposition between cognition and its object. In this dimension there is no need to substantiate compatibility between them — it is a level of primary foundation of knowledge. Consequently, any knowledge at this level may be characterized as “Ultimate”. That being said, place of such knowledge is (...) not taken by several specific statements, but by the certain way of organizing those “mental definitions” that are already used by common human sense. To organize these definitions, to arrange them into consistently deployed sequence of logical notions, there is need to abort the search for the primary foundation for knowledge inherent in philosophy from its very origins. This attempt was reflected in Kant's theory of knowledge, where the problem of the reliability of knowledge was solved due to self-limitation in the process of cognition — it was necessary to stop before a certain line, beyond which thought leaves “the limits of possible experience” and falls into the area of insoluble contradictions (antinomies). Hegel's Logic, which, according to the authors, is in a kind of “symbiosis” with the Kantian program, consists in considering these insoluble contradictions precisely as a “symptom” of achieving the primary foundation of knowledge. It is in the collision with an insoluble contradiction that the definitions are organized in the necessary logical sequence, and that fundamental level is reached where there is no opposition between cognition and its object. (shrink)

The article proposes to consider Hegel's “Science of Logic” as a project, where the most important thing is not to describe the “laws of thinking”, but rather to propose a more precise definition of the theoretical level at which thinking itself becomes the subject of its own description. Thus, on the one hand, Hegel reveals the paradox that lies at the basis of the logic as a philosophical discipline, and on the other, seeks to show the possibility of the existence (...) of the logic in the extreme conditions of this paradox. Within the framework of this approach, logic is inseparable from the theory of knowledge — it is assumed that the configuration or “form” of thinking cannot be “neutral” with respect to its content. Therefore, according to Hegel, in reality there is not the logic of isolated operations occurring in the mind, but the logic of “the object itself”, which shows and directly embodies itself in these operations. At this level, there is no gap between the thinking consciousness and objects of the external world separated from it. We are talking about a special — “pre-ontological” — dimension, where the subject's sensory experience is not yet launched and distinguished, and a subject of the thinking process and thinking itself form a single whole. Such a dimension is developed in the historical experience of philosophical thought, starting from Antiquity, and is captured by Hegel under the name of “Ultimate knowledge”. The article raises the question of why this dimension repeatedly eludes us, acquiring a “semi-mystical” status in the minds of Hegel's interpreters, and yet how it is still possible to infiltrate into it. (shrink)

The Riemannian manifold structure of the classical (i.e., Einsteinian) space-time is derived from the structure of an abstract infinite-dimensional separable Hilbert space S. For this S is first realized as a Hilbert space H of functions of abstract parameters. The space H is associated with the space of states of a macroscopic test-particle in the universe. The spatial localization of state of the particle through its interaction with the environment is associated with the selection of a submanifold M of realization (...) H. The submanifold M is then identified with the classical space (i.e., a space–like hypersurface in space-time). The mathematical formalism is developed which allows recovering of the usual Riemannian geometry on the classical space and, more generally, on space and time from the Hilbert structure on S. The specific functional realizations of S are capable of generating spacetimes of different geometry and topology. Variation of the length-type action functional on S is shown to produce both the equation of geodesics on M for macroscopic particles and the Schrödinger equation for microscopic particles. (shrink)

When discussing the French Revolution and Napoleon in his lectures from 1933 to 1939, Alexandre Kojève had in mind events in Russia. The clash between the “old order,” with its Masters, and the worker Slaves corresponded for him more with the images of pre-revolutionary Russian journalism than with the wigged aristocrats and French bourgeoisie of the end of the eighteenth century. In his lectures, behind Napoleon, as a revolutionary emperor, there exists, however secretly or openly, the figure of Stalin, with (...) his plans for the “building of socialism in one country,” his five-year plans, collectivization, and terror. Kojève’s ontology and anthropology diverge both from Hegel’s version of the two as well as with Marxism, incorporating different theses from Nietzsche and Heidegger’s Daseinanalytik. Just as in The Phenomenology of Spirit, terror plays a central role in interpreting revolution, yet it is conceived in the spirit of a Heideggerian “being-toward-death.” The relation between Master and Slave begins with fear of death, and it is destroyed by fear of death in the face of revolutionary terror. In this article, Kojève’s philosophy converges with the various versions of “left Nietzscheanism,” which were particularly widespread in prerevolutionary Russia. (shrink)