Epithelial tissues serve as critical barriers in metazoan organisms, maintaining structural integrity and facilitating essential physiological functions. Epithelial cell polarity regulates mechanical properties, signaling, and transport, ensuring tissue organization and homeostasis. However, the barrier function is challenged by cell turnover during development and maintenance. To preserve tissue integrity while removing dying or unwanted cells, epithelial tissues employ cell extrusion. This process removes both dead and live cells from the epithelial layer, typically causing detached cells to undergo apoptosis. Transformed cells, however, (...) often resist apoptosis, leading to multilayered structures and early carcinogenesis. Malignant cells may invade neighboring tissues. Loss of cell polarity can lead to multilayer formation, cell extrusion, and invasion. Recent studies indicate that multilayer formation in epithelial cells with polarity loss involves a mixture of wild‐type and mutant cells, leading to apical or basal accumulation. The directionality of accumulation is regulated by mutations in polarity complex genes. This phenomenon, distinct from traditional apical or basal extrusion, exhibits similarities to the endophytic or exophytic growth observed in human tumors. This review explores the regulation and implications of these phenomena for tissue biology and disease pathology. (shrink)

Ben shu quan mian chan shu zhu xi de li xue yu ke xue si xiang,Te bie jiu zhu xi zhong shi zi ran yan jiu,Shen ru ke xue tan suo,Chuang xin ke xue si xiang,Chuan bo zi ran zhi shi yi ji zhu xi li xue de ke xue jia zhi zhan kai ju ti de lun shu,Chong fen ken ding zhu xi ke xue si xiang dui yu hou shi ke ji fa zhan de zhong yao zuo yong,Yi (...) qi dui jin tian de ke ji yu wen hua de fa zhan zhu ru yuan tou huo shui. (shrink)

Ben shu xi "Zhuzi xue yan jiu cong shu" zhi yi zhong. Zuo zhe cong Zhuzi ge zhi lun xing cheng de xue shu bei jing, ge zhi lun jian gou de xin lu li cheng, ge zhi lun de li lun nei han, ge zhi lun yu ke xue yan jiu, Zhuzi men ren ji hou xue de ge zhi lun, Zhuzi ge zhi lun de yan bian yu ge zhi xue deng fang mian xiang xi lun shu le (...) Zhuzi de ge wu zhi zhi lun si xiang. (shrink)

This paper is an outline of micro-epistemology as a philosophical reflection of "quantum wealth" as well as an anthropological analysis of the nature of human cognition in the scale of quantum. It covers the problems of the observation in and the trueness of micro-cognition, the perception of quantum phenomena, the relations between micro-cognition and practice as well as between macro-subject and micro-object, the descriptive turn in micro-cognition, the description of micro-world and some special descriptive problems in micro-cognition, etc. Micro-cognition, just (...) as quantum theory shows, relates to a scale out of ordinary for human being. Quantum theory means a farther clarification of the background of human person’s existence and the human-world relation. It means anenormous extending of the framework of scientific theory, and thereby the rebuilding of the foundation of philosophy. It also means the refining and the rationalization of our conceptual tools and, in a certain extent, the reconstruction of the foundation of epistemology. (shrink)

本书共分七章,主要内容包括:分析法学概述、分析法学的形成、分析法学传统、凯尔森的纯粹法学、哈特的新分析法学、分析法学的新近发展、对分析法学的评价。.

本书通过对宋代儒学与宋代科学的关联性的研究,深入探讨宋代儒学对于宋代科学发展的影响;具体阐述宋代各个时期著名儒家学者对于自然知识以及科学的重视和研究、宋代儒学精神与思想对宋代科学家及其科学研究的影响.

Science and Society presents comments on some of the social and economic implications of the new biology. Here, Cao Tian‐qin presents a perspective from China on recent developments in biotechnology.

When humans are addressing multiple robots with informative speech acts, their cognitive resources are shared between all the participating robot agents. For each moment, the user’s behavior is not only determined by the actions of the robot that they are directly gazing at, but also shaped by the behaviors from all the other robots in the shared environment. We define cooperative behavior as the action performed by the robots that are not capturing the user’s direct attention. In this paper, we (...) are interested in how the human participants adjust and coordinate their own behavioral cues when the robot agents are performing different cooperative gaze behaviors. A novel gaze-contingent platform was designed and implemented. The robots’ behaviors were triggered by the participant’s attentional shifts in real time. Results showed that the human participants were highly sensitive when the robot agents were performing different cooperative gazing behaviors. Keywords: human-robot interaction; multi-robot interaction; multiparty interaction; eye gaze cue; embodied conversational agent. (shrink)

The sensitive period for phonetic learning, evidenced by improved native speech processing and declined non-native speech processing, represents an early milestone in language acquisition. We examined the extent that sensory encoding of speech is altered by experience during this period by testing two hypotheses: early sensory encoding of non-native speech declines as infants gain native-language experience, and music intervention reverses this decline. We longitudinally measured the frequency-following response, a robust indicator of early sensory encoding along the auditory pathway, to a (...) Mandarin lexical tone in 7- and 11-months-old monolingual English-learning infants. Infants received either no intervention or music intervention randomly between FFR recordings. The language-experience group exhibited the expected decline in FFR pitch-tracking accuracy to the Mandarin tone, while the music-intervention group did not. Our results support both hypotheses and demonstrate that both language and music experiences alter infants’ speech encoding. (shrink)

TODIM is a well-known multiple-criteria decision-making which considers the bounded rationality of decision makers based on prospect theory. However, in the classical TODIM, the perceived probability weighting function and the difference of the risk attitudes for gains and losses are not consistent with the original idea of PT. Moreover, probabilistic hesitant fuzzy information shows its superiority in handling the situation that the DMs hesitate among several possible values with different possibilities. Hence, a novel TODIM with probabilistic hesitant fuzzy information is (...) proposed in this paper to simulate the perceptions of the DMs in PT. To show the advantages of the proposed method, a novel TODIM is combined with hesitant fuzzy information. Finally, a case study is carried out to demonstrate the feasibility of the proposed method, and a series of comparative analyses and the sensitivity analyses are used to show the stability of the proposed method. (shrink)

From reviews of the hardback edition: a deep study of 20th century field ... of the conceptual origins and development of twentieth century field theories, ...

대부분의 연구자들은 주염계의 「태극도설」에 대한 주자의 해석서인 「태극해의」가 이기론을 기반으로 이루어졌다고 주장한다. 그러나 「태극해의」에서 ‘태극=리’라고 명시적으로 주장한 구절은 찾아볼 수 없으며 체계적인 이기론이 나타나지도 않는다. 이와 같은 사실에 비추어 볼 때에 조선유학자들이 이기론을 사용하여 「태극도설」을 해석한 것은 의미가 있다. 남당은 ‘모두 같은 본연지성’과 ‘모두 다른 기질지성’이라는 기존의 이분법적 성론만으로는 인간과 사물의 차이를 본질적으로, 그리고 명실상부하게 분별할 수 없으며, 인간이 도덕적 주체로서 가지는 고유한 지위를 확보하기 어렵다고 보았다. 이와 같은 문제의식에서 남당은 본연지성을 ‘초형기의 본연지성’과 ‘인기질의 본연지성’으로 나누고, 因氣質의 ‘人性과 物性이 다른 (...) 本然之性’이라는 독창적 개념을 토대로 「태극도설」을 해석하였다. 그리고 이 성론에 기반을 둔 ‘一原分殊’의 논리로 「태극도설」에 통일적인 체계를 부여하였다. 그는 리와 기의 분별을 매우 강조하고 있다. 이 분별의 논리가 인물성동이론에 적용될 때 인/물의 본연지성이 다르며 성인과 범인의 마음이 다르다는 ‘차이’의 이론이 정립된다. 그리고 이를 토대로 ‘차이의 형이상학’이 구축된다. 남당은 이 ‘차이의 형이상학’을 기반으로 「태극도설」을 해석하여 통일적인 체계성을 부여한 것이다. 이와 같은 남당의 해석이 ‘동아시아 유학자들의 「태극도설」 해석사에 있어서 어떠한 위상을 차지하고 있는가’라는 문제는 앞으로 중요한 연구과제가 될 것이다. 성리학의 핵심적 쟁점들은 「태극도설」과 밀접한 관계에 있기 때문이다. (shrink)

Contingent reinforcement behavior is generally regarded as one of the key elements of being a “good” leader, yet the question of what happens when this behavior is absent has received little attention in past empirical research. Drawing upon self-regulation theory, we develop and test a model that specifies the effects of leader reward omission on employes’ deviant behavior. Using the data of 230 workers from two manufacturing companies located in South China collected across three time points, we find that leader (...) reward omission is positively associated with deviant behavior. Moreover, the indirect effects of leader reward omission on employes’ deviant behavior are mediated by moral disengagement. Our study also reveals that Machiavellianism can aggravate the positive effect of leader reward omission on moral disengagement, and subsequently exacerbate the indirect effect on employes’ deviant behavior. Taken together, our findings reveal the consequences of leader reward omission, and the importance of examining subordinate self-regulation under the lack of positive reinforcement. (shrink)

This paper examines the impact of Chinese business managers’ moral philosophies on the perception of corrupt payments such as bribery, kickbacks and gift giving. Business managers from Mainland China were selected as target respondents. As hypothesized the survey results generally indicate that moral relativism is a significant predictor of Chinese business managers’ favorable perception of bribery and kickbacks. In examining the attitude toward gift giving, the survey showed that an individual’s attitude toward gift giving was neither affected by their moral (...) relativism nor by their moral idealism, which implies that gift giving is widely accepted as legal practice in business in Chinese cultural society. (shrink)

“Entire philosophy, especially the basic important point of contemporary philosophy, is the connected point between logic and existence.” The top, basic and key point is logic and existence or spirit and matter. How to understand this point becomes the important symbol of different development stages and different philosophy schools, one’s essence of world outlook as well. Philosophy, which belongs to thinking field, pertains to “software system”, is the platform for scientific research of other subjects. Formula One, the universe is rooted (...) in matter, united in spirit; Formula Two, the universe is potential energy. Formula Three, the universe is function. Modernization is digital! Digital philosophy! Digital spirit world! (shrink)

Experience and science, being the two sources of technology, have different focuses. In experiential technology, techniques and skills are emphasized while in scientific technology tool or equipment. Experiential technology is generally regarded as local knowledge, and scientific technology universal. Traditional Chinese medicine is an experiential technology. In contrast, Western medicine is set up as a scientific technology with great efforts. Through the comparison of these two medicines, this paper attempts to illustrate the difference between the two technologies and in turn, (...) the difference between these two medicines by defining these two technologies. Finally, this paper further investigates the special values of Chinese medicine. Making use of the SSK theory, this paper deconstructs the idea of universality of science, and argues that, the universality is the feature that science pursues, but not what it already has. With more historical evidence, experiential technology is more stable, while scientific technology is less stable because it updates quickly, and often changes reversely. (shrink)

This study had two aims: to test the effect and the effect size of specific problematic Internet use [online shopping, online pornography, social network site usage, and Internet gaming] on generalized problematic Internet use and to reveal the gender differences in GPIU and SPIU for students from the elementary school level to the university level. In total, 5,215 Chinese students from four types of schools provided self-report data on demographic variables, online shopping, online pornography, SNS usage, Internet gaming, and GPIU. (...) After calculations had been controlled for demographic variables, the results indicated that online shopping, online pornography, SNS usage, and Internet gaming positively predicted GPIU—and Internet gaming was the most critical predictor of GPIU—and that gender differences were revealed in Internet gaming and GPIU in all educational levels, except at senior high school where the gender differences in GPIU were not significant. Significant gender differences were found for online shopping and online pornography for all educational levels above elementary school. These results provided further understanding of the association between GPIU and SPIU and gender differences in PIU, which suggested that gender differences across different educational levels should be considered in interventions of PIU. (shrink)

Proactive personality is a key determinant of entrepreneurial intention. Few studies have explored the mediating and moderating mechanisms underlying this relationship. This study investigates the association between proactive personality and entrepreneurial intention and examines the mediating role of perceived entrepreneurial support and the moderating role of gender. Using a cross-sectional design, 1,515 senior students from Chinese private colleges were recruited using random cluster sampling. They completed a battery of self-reported online questionnaires on proactive personality, perceived entrepreneurial support, and entrepreneurial intention. (...) The results revealed that perceived entrepreneurial support mediates the association between proactive personality and entrepreneurial intention. Moderated mediation analysis indicated that the relationship between proactive personality and perceived entrepreneurial support and that between perceived entrepreneurial support and entrepreneurial intention are moderated by gender. Specifically, the positive association between proactive personality and entrepreneurial intention was stronger in male students, and the positive association between perceived entrepreneurial support and entrepreneurial intention was stronger in female students. This study contributes to the understanding of how proactive personality predicts entrepreneurial intention in Chinese private college students and bears implications for higher education institutions and policymakers that entrepreneurship promotion agenda should focus on improving perceived entrepreneurial support and considering the gender of students. (shrink)

Of the three powers—Wei, Shu, and Wu—that divided China for the better part of the third century, Wei has received the most attention in the standard literary historical accounts. In a typical book of Chinese literary history in any language, little, if anything, is said about Wu and Shu. This article argues that the consideration of the literary production of Shu and Wu is crucial to a fuller picture of the cultural dynamics of the Three Kingdoms period. The three states (...) competed with one another for the claim to political legitimacy and cultural supremacy, and Wu in particular was in a position to contend with Wei in its cultural undertakings, notably in the areas of history writing and ritual music. This article begins with an overview of Shu and Wu literary production, and moves on to a more detailed discussion of Wu’s cultural projects, both of which were intended to assert Wu’s legitimacy and cultural power vis-à-vis Wei and Shu’s claims to cultural and political orthodoxy. Ultimately, this article implicitly asks the question of how to write literary history when there is scant material from the period under question, and suggests that we perform textual excavations and make use of what we have to try and reconstruct, as best as we can, what once was. A good literary history of the Chinese medieval period, the age of manuscript culture and that of heavy textual losses and transfigurations, should be written with the awareness of the incomplete and imperfect nature of the data we do have, and incorporate the phenomenon of textual losses and transfigurations as well as some reflections on the underlying reasons into its narrative and critical inquiry. (shrink)

This paper is an introduction to micro-epistemology, philosophical reflection of "quantum wealth" as well as an anthropological analysis of the nature of human cognition in the scale of quantum. It covers the problems of the observation in and the trueness of micro-cognition, the perception of quantum phenomena, the relations between micro-cognition and practice as well as between macro-subject and micro-object, the descriptological turn in micro-cognition, the description of micro-world and some special descriptological problems in micro-cognition, etc. Micro-cognition, just as quantum (...) theory shows, relates to a scale out ofordinary for human being. Quantum theory means a farther clarification of the background of human person’s existence and the human-world relation. It means an enormous extending of the framework of scientific theory, and thereby the rebuilding of the foundation of philosophy. It also means the refining and therationalization of our conceptual tools and, in a certain extent, the reconstruction of the foundation of epistemology. (shrink)

Complex natural resources issues including sustainable agriculture require diverse stakeholders to take voluntary and even coordinated actions. Social learning is a critical process for stakeholders to navigate differences in knowledge, values, and ways of knowing while building trust and coordination capacity. Integrating the social learning approach along with social networks, well-proposed, well-designed, and effectively facilitated stakeholder engagement events can promote bridging and information exchange by capitalizing on stakeholder interests and formal and informal interaction opportunities. We collected survey data before and (...) after a stakeholder engagement event for a USDA Long-term Agroecosystem Research (LTAR) site in the summer of 2022. A total of 76 individuals participated in the event coming from diverse groups in the agricultural community, including representatives from agribusiness, extension, farm advisers, farmers, nonprofit organizations, state and federal agencies, and university-affiliated researchers and staff. We conducted two-mode network analyses for participant interests and evaluated connections with other stakeholder groups before and then again after the event. We also explored emerging information exchange ties along with the levels of similarity of these new ties. We found that participating stakeholder groups shared an interest in having greater connections to farmers. Many of the new connections were across affiliation groups and people with different views suggesting opportunities for information exchange. Results demonstrate the value of stakeholder engagement events based on stakeholder interests for facilitating the formation of bridging ties that support social learning. (shrink)

The history of Chinese Marxist thought is intimately intertwined with ancient autochthonous philosophical texts. In Chinese Dialectics the complete intellectual history of Chinese Marxism is laid bare.

With the growing importance of China and other Asian economies in international business, both executives and academic researchers are eager to understand the unique aspects of Asian business practices. Extant literature suggests that market orientation has a positive effect on firm performance in China. However, the moral and social norms in China are very different from those in Western societies; a business orientation developed based on Confucius ethics, a core Chinese philosophy that affects China and many Asian economies, should provide (...) an alternative, or even better, explanation of Chinese companies’ business practices and successes than market orientation, which is developed in the West. On the basis of content analysis of ancient Chinese literature and case studies of recent events in Asian, this paper aims to propose Jun-zi orientation as a more cultural-specific organizational orientation alternative to market orientation for use in East Asian business context. Specifically, this paper provides extensive literature review on Jun-zi concept, a major concept in Confucianism and its five virtues. The effects of Jun-zi orientation and its five virtues on different aspects of business performance are also discussed. (shrink)

本书包括:第一章:军事美的本质、第二章:军事美的审美范畴、第三章:军事审美形态、第四章:中国人民解放军军事美等。.