Results for ' temporal regulation'

955 found
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  1.  15
    Temporally regulated expression of insulin and insulin‐like growth factors and their receptors in early mammalian development.Susan Heyner, Robert M. Smith & Gilbert A. Schultz - 1989 - Bioessays 11 (6):171-176.
    Recent studies of early development in a number of ivertebrate and vertebrate species have suggested that growth factors and their receptors may play important roles in differentiation as well as cell proliferation. In the mouse embryo, the expression of the receptors for insulin and insulin‐like growth factors I and II (IGF‐I and ‐II) are temporally regulated. The ontogeny of receptor and ligand expression within the insulin and IGF gene family suggests that the very earliest stages of mammalian embryogenesis may be (...)
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  2.  34
    Tadpole competence and tissue‐specific temporal regulation of amphibian metamorphosis: Roles of thyroid hormone and its receptors.Yun-Bo Shi, J. Wong, M. Puzianowska-Kuznicka & M. A. Stolow - 1996 - Bioessays 18 (5):391-399.
    Amphibian metamorphosis is a post‐embryonic process that systematically transforms different tissues in a tadpole. Thyroid hormone plays a causative role in this complex process by inducing a cascade of gene regulation. While natural metamorphosis does not occur until endogenous thyroid hormone has been synthesized, tadpoles are competent to respond to exogenous thyroid hormone shortly after hatching. In addition, even though the metamorphic transitions of individual organs are all controlled by thyroid hormone, each occurs at distinct developmental stages. Recent molecular (...)
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  3.  47
    Emotion regulation and the temporal dynamics of emotions: Effects of cognitive reappraisal and expressive suppression on emotional inertia.Peter Koval, Emily A. Butler, Tom Hollenstein, Dianna Lanteigne & Peter Kuppens - 2015 - Cognition and Emotion 29 (5):831-851.
    The tendency for emotions to be predictable over time, labelled emotional inertia, has been linked to low well-being and is thought to reflect impaired emotion regulation. However, almost no studies have examined how emotion regulation relates to emotional inertia. We examined the effects of cognitive reappraisal and expressive suppression on the inertia of behavioural, subjective and physiological measures of emotion. In Study 1 (N = 111), trait suppression was associated with higher inertia of negative behaviours. We replicated this (...)
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  4.  24
    Temporal Assessment of Self-Regulated Learning by Mining Students’ Think-Aloud Protocols.Lyn Lim, Maria Bannert, Joep van der Graaf, Inge Molenaar, Yizhou Fan, Jonathan Kilgour, Johanna Moore & Dragan Gašević - 2021 - Frontiers in Psychology 12:749749.
    It has been widely theorized and empirically proven that self-regulated learning (SRL) is related to more desired learning outcomes, e.g., higher performance in transfer tests. Research has shifted to understanding the role of SRL during learning, such as the strategies and learning activities, learners employ and engage in the different SRL phases, which contribute to learning achievement. From a methodological perspective, measuring SRL using think-aloud data has been shown to be more insightful than self-report surveys as it helps better in (...)
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  5.  38
    Temporal Perspectives of the Nanotechnological Challenge to Regulation: How Human Rights Can Contribute to the Present and Future of Nanotechnologies.Daniele Ruggiu - 2013 - NanoEthics 7 (3):201-215.
    Expectations play a central role in understanding scientific and technological changes. Future-oriented representations are also central with regard to nanotechnologies as they can guide policy activities, provide structures and legitimation, attract different interests, focus policy-makers’ attention and foster investments for research. However, the emphasis on future scenarios tends to underrate the complexity of the challenges of the present market of nanotechnologies by flattening them under the needs and promises of scientific research. This is particularly apparent if we consider the viewpoint (...)
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  6.  54
    Using temporal distancing to regulate emotion in adolescence: modulation by reactive aggression.S. P. Ahmed, L. H. Somerville & C. L. Sebastian - 2017 - Cognition and Emotion 32 (4):812-826.
    ABSTRACTAdopting a temporally distant perspective on stressors reduces distress in adults. Here we investigate whether the extent to which individuals project themselves into the future influences distancing efficacy. We also examined modulating effects of age across adolescence and reactive aggression: factors associated with reduced future-thinking and poor emotion regulation. Participants read scenarios and rated negative affect when adopting a distant-future perspective, near-future perspective, or when reacting naturally. Self-report data revealed significant downregulation of negative affect during the distant-future condition, with (...)
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  7.  32
    Temporal and spatial regulation of developmentally expressed genes in Caulobacter.James W. Gober & Lucy Shapiro - 1991 - Bioessays 13 (6):277-283.
    Fundamental problems in developmental biology, such as the generation of asymmetry, differential transcription, and the execution of positional information, are all exhibited by a prokaryotic system, the Caulobacter cell cycle. Progeny cells resulting from each cell division have different developmental programs with respect to patterns of transcription and the initiation of DNA replication. The binary fission that yields dissimilar progeny results from asymmetry generated in the parent cell. An aspect of this fundamental developmental event is the temporally‐controlled biogenesis of a (...)
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  8.  62
    Temporal self-regulation theory: a neurobiologically informed model for physical activity behavior.Peter A. Hall & Geoffrey T. Fong - 2015 - Frontiers in Human Neuroscience 9.
  9.  34
    Control of developmental timing by small temporal RNAs: a paradigm for RNA‐mediated regulation of gene expression.Diya Banerjee & Frank Slack - 2002 - Bioessays 24 (2):119-129.
    Heterochronic genes control the timing of developmental programs. In C. elegans, two key genes in the heterochronic pathway, lin-4 and let-7, encode small temporally expressed RNAs (stRNAs) that are not translated into protein. These stRNAs exert negative post-transcriptional regulation by binding to complementary sequences in the 3′ untranslated regions of their target genes. stRNAs are transcribed as longer precursor RNAs that are processed by the RNase Dicer/DCR-1 and members of the RDE-1/AGO1 family of proteins, which are better known for (...)
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  10.  18
    Eyes wide open: Regulation of arousal by temporal expectations.Nir Shalev & Anna C. Nobre - 2022 - Cognition 224 (C):105062.
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  11.  33
    Temporal sociomedical approaches to intersex* bodies.Limor Meoded Danon - 2022 - History and Philosophy of the Life Sciences 44 (2):1-28.
    The history of the field of intersex bodies/bodies with variations of sex development reflects the ongoing tension between sociomedical attempts to control uncertainty and reduce the duration of corporeal uncertainty by means of early diagnosis and treatment, and the embodied subjects who resist or challenge these attempts, which ultimately increase uncertainty. Based on various qualitative studies in the field of intersex, this article describes three temporal sociomedical approaches that have evolved over the last decade and aims to address the (...)
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  12.  10
    Regulation of gene expression in developing epidermal epithelia.Carolyn Byrne - 1997 - Bioessays 19 (8):691-698.
    Skin is one of the most thoroughly studied epithelia and can be used as a model for transcriptional control of epithelial differentiation. In particular, the stages of epidermal development and differentiation from a simple epithelium are well characterized. Temporal gene expression during development can be used to assign roles for transcription factors in epidermal differentiation. Approaches to understanding transcriptional regulation in epidermis include extensive promoter analysis and expression studies, in some cases coupled to functional studies. This work has (...)
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  13.  32
    Temporality Naturalized.Koichiro Matsuno - 2018 - Philosophies 3 (4):45--0.
    The Schrödinger equation for quantum mechanics, which is approachable in third-person description, takes for granted tenseless time that does not distinguish between different tenses such as past, present, and future. The time-reversal symmetry grounded upon tenseless time globally may, however, be broken once measurement in the form of exchanging indivisible quantum particles between the measured and the measuring intervenes. Measurement breaks tenseless time locally and distinguishes different tenses. Since measurement is about the material process of feeding and acting upon the (...)
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  14. Temporal changes in ovarian gonadotropin-releasing hormone mRNA levels by gonadotropins in the rat.Sun Kyeong Yu - 1994 - Mol Cells 4:39-44.
    Temporal Changes in Ovarian Gonadotropin-Releasing Hormone mRNA Levels by Gonadotropins in the Rat Sung Ho Lee, Eun-Seob Song, Sun Kyeong Yu, Changmee Kim, Dae Kee Lee, Wan Sung Choi l and Kyungjin Kim* Department of Molecular Biofogy and SRC for Cell Differentiation, Seoul National University, Seoul 150-742, Korea; IDepartment of Anatomy, College of Medicine, Gyeongsanf; National University, Chinju 660-280, Korea (Recei·. cd on December 29, 1993) The present study examines whether gonadotropins are involved in the regulation of ovarian (...)
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  15.  20
    Model of Calcium Dynamics Regulating IP3IP_{3}, ATP and Insulin Production in a Pancreatic β\beta-Cell. Vaishali & Neeru Adlakha - 2024 - Acta Biotheoretica 72 (1):1-26.
    The calcium signals regulate the production and secretion of many signaling molecules like inositol trisphosphate ( IP3IP_{3} ) and adenosine triphosphate (ATP) in various cells including pancreatic β\beta -cells. The calcium signaling mechanisms regulating IP3IP_{3}, ATP and insulin responsible for various functions of β\beta -cells are still not well understood. Any disturbance in these mechanisms can alter the functions of β\beta -cells leading to diabetes and metabolic disorders. Therefore, a mathematical model is proposed by incorporating the reaction-diffusion equation for calcium (...)
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  16.  39
    Temporalization and the Digital Vigilante: Past Presencing, Un/Doing Futures and “Jewish Revenge” as Affective Justice in Talia Lavin’s Culture Warlords.Todd Sekuler - 2024 - Studies in Social Justice 18 (2):323-343.
    This paper examines the figure of the hate-fighting digital vigilante as embodied through Aryan Queen, an online persona developed and depicted by self-proclaimed antifa member Talia Lavin in her book Culture Warlords. One chapter in the 2020 memoir relays Lavin’s pursuits to elicit and make known identifying information of Der Stürmer, an anonymous white supremacist online hater. I first locate Lavin’s undertaking in the porous policy landscape regulating online hate transnationally to make a case for its value as an entry (...)
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  17.  5
    Time-dependent relations between emotion regulation, frustration, and metacognitive strategy use in technology-mediated learning.Valentin Riemer - 2024 - Cognition and Emotion 38 (8):1383-1392.
    Understanding how learners regulate their emotions and engage in metacognitive strategies is crucial for fostering self-regulated learning, particularly in technology-mediated learning. This study examines the temporal relationships between two emotion regulation (ER) strategies, reappraisal and suppression, frustration, and use of progress monitoring as metacognitive strategy, within the context of an educational game on financial literacy. The study involved 82 undergraduate students whose levels of frustration, progress monitoring behaviour, ER strategies were assessed at various points during the learning task. (...)
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  18.  31
    Author Reply: Coregulation is a State of a Temporal Interpersonal Emotion System.Emily A. Butler & Ashley K. Randall - 2013 - Emotion Review 5 (2):213-214.
    People in an emotional exchange form a temporal interpersonal emotion system (TIES), in which their emotions are interconnected over time (Butler, 2011). These systems can be in various states, defined by the pattern of emotional interconnections. We have defined coregulation as one such state involving coupled dampened oscillations between partners’ emotions that converge on a stable level. Coregulation could be distinguished from other states, such as stress buffering, by comparing statistical models that represent the theoretical distinctions between states. Optimal (...)
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  19.  18
    Introducing Temporal Theory to the Field of Sport Psychology: Toward a Conceptual Model of Time Perspectives in Athletes’ Functioning.Maciej Stolarski, Wojciech Waleriańczyk & Dominika Pruszczak - 2019 - Frontiers in Psychology 9:413060.
    Time perspective theory provides a robust conceptual framework for analyzing human behavior in the context of time. So far, the concept has been studied and applied in multiple life domains, such as education, health, social relationships, environmental behavior, or financial behavior; however its explanatory potential has been completely neglected within the domain of sport. In the present paper we provide a deepened theoretical analysis of the potential role of temporal framing of human experience for sport-related attitudes, emotions, and athletic (...)
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  20.  19
    Cellular oscillations and the regulation of growth: the pollen tube paradigm.José A. Feijó, Joaquim Sainhas, Terena Holdaway-Clarke, M. Sofia Cordeiro, Joseph G. Kunkel & Peter K. Hepler - 2001 - Bioessays 23 (1):86-94.
    The occurrence of oscillatory behaviours in living cells can be viewed as a visible consequence of stable, regulatory homeostatic cycles. Therefore, they may be used as experimental windows on the underlying physiological mechanisms. Recent studies show that growing pollen tubes are an excellent biological model for these purposes. They unite experimental simplicity with clear oscillatory patterns of both structural and temporal features, most being measurable during real‐time in live cells. There is evidence that these cellular oscillators involve an integrated (...)
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  21.  28
    Cell Fate and Developmental Regulation Dynamics by Polycomb Proteins and 3D Genome Architecture.Vincent Loubiere, Anne-Marie Martinez & Giacomo Cavalli - 2019 - Bioessays 41 (3):1800222.
    Targeted transitions in chromatin states at thousands of genes are essential drivers of eukaryotic development. Therefore, understanding the in vivo dynamics of epigenetic regulators is crucial for deciphering the mechanisms underpinning cell fate decisions. This review illustrates how, in addition to its cell memory function, the Polycomb group of transcriptional regulators orchestrates temporal, cell and tissue‐specific expression of master genes during development. These highly sophisticated developmental transitions are dependent on the context‐ and tissue‐specific assembly of the different types of (...)
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  22.  80
    Regulation of the Neural Circuitry of Emotion by Compassion Meditation: Effects of Meditative Expertise.Antoine Lutz, Julie Brefczynski-Lewis & Richard J. Davidson - unknown
    Recent brain imaging studies using functional magnetic resonance imaging (fMRI) have implicated insula and anterior cingulate cortices in the empathic response to another’s pain. However, virtually nothing is known about the impact of the voluntary generation of compassion on this network. To investigate these questions we assessed brain activity using fMRI while novice and expert meditation practitioners generated a loving-kindness-compassion meditation state. To probe affective reactivity, we presented emotional and neutral sounds during the meditation and comparison periods. Our main hypothesis (...)
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  23.  15
    Does replication‐induced transcription regulate synthesis of the myriad low copy number proteins of Escherichia coli?Purnananda Guptasarma - 1995 - Bioessays 17 (11):987-997.
    Over 80% of the genes in the E. coli chromosome express fewer than a hundred copies each of their protein products per cell. It is argued here that transcription of these genes is neither constitutive nor regulated by protein factors, but rather, induced by the act of replication. The utility of such replication‐induced (RI) transcription to the temporal regulation of synthesis of determinate quantities of low copy number (LCN) proteins is described. It is suggested that RI transcription may (...)
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  24.  38
    (1 other version)Addiction as temporal disruption: interoception, self, meaning.Ryan Kemp - 2018 - Phenomenology and the Cognitive Sciences:1-15.
    Addiction remains a challenging disorder, both to treat and to conceptualise. While the temporal dimension of addiction has been noted before, here the aim is to ground this understanding in a coherent phenomenological-neuroscience framework. Addiction is partly understood as drawing the subject into a predominantly “now” orientated existence, with the future closed or experienced as extremely distant. Another feature of this temporal structuring is that past experiences, which are crucial in advancing intentionally forward, are experienced in addiction as (...)
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  25.  20
    Polycomb Repressive Complexes in Hox Gene Regulation: Silencing and Beyond.Claudia Gentile & Marie Kmita - 2020 - Bioessays 42 (10):1900249.
    The coordinated expression of the Hox gene family encoding transcription factors is critical for proper embryonic development and patterning. Major efforts have thus been dedicated to understanding mechanisms controlling Hox expression. In addition to the temporal and spatial sequential activation of Hox genes, proper embryonic development requires that Hox genes get differentially silenced in a cell‐type specific manner as development proceeds. Factors contributing to Hox silencing include the polycomb repressive complexes (PRCs), which control gene expression through epigenetic modifications. This (...)
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  26.  53
    Theory-guided Therapeutic Function of Music to facilitate emotion regulation development in preschool-aged children.Kimberly Sena Moore & Deanna Hanson-Abromeit - 2015 - Frontiers in Human Neuroscience 9:146406.
    Emotion regulation is an umbrella term to describe interactive, goal-dependent explicit and implicit processes that are intended to help an individual manage and shift an emotional experience. The primary window for appropriate emotion regulation development occurs during the infant, toddler, and preschool years. Atypical emotion regulation development is considered a risk factor for mental health problems and has been implicated as a primary mechanism underlying childhood pathologies. Current treatments are predominantly verbal- and behavioral-based and lack the opportunity (...)
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  27.  24
    Contesting Settler Colonial Accounts: Temporality, Migration and Place-Making in Scarborough, Ontario.Paloma E. Villegas, Patricia Landolt, Victoria Freeman, Joe Hermer, Ranu Basu & Bojana Videkanic - 2021 - Studies in Social Justice 14 (2):321-351.
    The paper considers how the logic of settler colonialism, the active and ongoing dispossession of Indigenous peoples, shapes scholarship on migration, race and citizenship in Canada. It draws on the insights of settler colonial theory and critiques of methodological nationalism to do so. The concept of differential inclusion and assemblages methodology are proposed as a way to understand the relationship between Indigeneity and migration in a settler colonial context. The paper develops this conceptual proposal through an analysis of a single (...)
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  28.  12
    Desmond Manderson, Danse Macabre: Temporalities of Law in the Visual Arts.Anne Brunon-Ernst - 2019 - Revue D’Études Benthamiennes 16.
    “Every culture is first and foremost a particular experience of time” Giorgio Agamben, History and Infancy: the Destruction of Experience, trans. Liz Heron, Verso, 1993, p. 91 Desmond Manderson’s book, Danse Macabre, is an essential read which reminds us that “the visual and spectacular are indispensable elements of how we come to know and are known by politics, law, and regulation”. It presents remarkable research on visual representations of the law, achieving the difficult task of...
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  29.  16
    Algorhythmic governance: Regulating the ‘heartbeat’ of a city using the Internet of Things.Rob Kitchin & Claudio Coletta - 2017 - Big Data and Society 4 (2).
    To date, research examining the socio-spatial effects of smart city technologies have charted how they are reconfiguring the production of space, spatiality and mobility, and how urban space is governed, but have paid little attention to how the temporality of cities is being reshaped by systems and infrastructure that capture, process and act on real-time data. In this article, we map out the ways in which city-scale Internet of Things infrastructures, and their associated networks of sensors, meters, transponders, actuators and (...)
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  30.  2
    Toward a temporal ecology of hybrid professional training systems.Bruno Grave - 2024 - Revue Phronesis 13 (4):41-55.
    Over the past fifteen years, progress in distance learning and digital engineering has led to the emergence of so-called " hybrid " systems bringing together different modalities: face-to-face, distance learning, individual, collective, synchronous, or asynchronous. Our study, a survey of stakeholders in five hybrid didactic training systems for beginner teachers, explores how the efficiency and effectiveness of such hybrid systems result from the synchronization of rhythmicities experienced, constructed, or to be created. Do these rhythmicities thus created give the whole a (...)
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  31.  26
    The regulation of the yolk protein genes, a family of sex differentiation genes in Drosophila melanogaster.Mary Bownes - 1994 - Bioessays 16 (10):745-752.
    There are many obvious morphological and behavioural differences between male and female Drosophila, whose differing phenotypes are produced by a hierarchy of sex determination genes. These genes have been well characterised at the genetic and molecular level. Similarly, a number of sex‐specific differentiation genes have been characterised, such as the chorion and vitelline membrane genes in females and the sex peptide and other accessory gland proteins in males. Despite the depth of these parallel studies, there is only one example of (...)
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  32.  17
    The regulation of cellular differentiation in the dimorphic yeast Candida albicans.David R. Soll - 1986 - Bioessays 5 (1):5-11.
    Dimorphism in the yeast Candida albicans provides an unusually simple model system for investigating the mechanisms which regulate cellular differentiation, or cell divergence. Under the regime of pH‐regulated dimorphism, it has been demonstrated that the programs of protein synthesis accompanying bud and hypha formation are strikingly similar. Instead of dramatic differences in the repertoire of gene products possessed by bud‐ and hypha‐forming cells, subtle temporal, spatial and quantitative differences in the same architectural events appear to be basic to the (...)
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  33.  14
    Levinas, Kant and the Problematic of Temporality.Adonis Frangeskou - 2017 - London: Imprint: Palgrave Macmillan.
    The book offers an ethical interpretation of the Critique of Pure Reason by establishing the historical connection between the problematic of Temporality in the philosophies of Heidegger and Levinas on the one hand, and the ground-laying of metaphysics in the schematism of Kant's critical philosophy on the other. Drawing on Levinas' ethical critique of the Heideggerian problematic of Temporality together with his destructive proposal to carry out the deformalization of the Kantian notion of time in a manner consistent with Rosenzweig's (...)
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  34.  12
    Projection of Meaning in Fronto-Temporal Dementia.Ing-Mari Tallberg - 1999 - Discourse Studies 1 (4):455-477.
    The phenomenon of confabulation has achieved little linguistic attention although it concerns aberrant utterances. Most studies have been carried out from a neuropsychiatric point of view. The aim of this study was to examine confabulate constructions with focus on the impact of time course and context on projections of meaning. Confabulate speech produced by individuals with fronto-temporal dementia was investigated. A questionnaire was used to elicit confabulations in two individuals with severe FTD. Correct answers were uttered promptly, but were (...)
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  35.  17
    Species‐specific micro RNA regulation influences phenotypic variability.Eyal Mor & Noam Shomron - 2013 - Bioessays 35 (10):881-888.
    Phenotypic divergence among animal species may be due in part to species‐specific (SS) regulation of gene expression by small, non‐coding regulatory RNAs termed “microRNAs”. This phenomenon can be modulated by several variables. First, microRNA genes vary by their level of conservation, many of them being SS, or unique to a particular evolutionary lineage. Second, microRNA expression levels vary spatially and temporally in different species. Lastly, while microRNAs bind the 3′UTR of target genes in order to silence their expression, the (...)
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  36.  26
    Mechanisms regulating phosphatase specificity and the removal of individual phosphorylation sites during mitotic exit.Samuel Rogers, Rachael McCloy, D. Neil Watkins & Andrew Burgess - 2016 - Bioessays 38 (S1):24-32.
    Entry into mitosis is driven by the activity of kinases, which phosphorylate over 7000 proteins on multiple sites. For cells to exit mitosis and segregate their genome correctly, these phosphorylations must be removed in a specific temporal order. This raises a critical and important question: how are specific phosphorylation sites on an individual protein removed? Traditionally, the temporal order of dephosphorylation was attributed to decreasing kinase activity. However, recent evidence in human cells has identified unique patterns of dephosphorylation (...)
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  37.  16
    Tracking Changes in Students’ Online Self-Regulated Learning Behaviors and Achievement Goals Using Trace Clustering and Process Mining.Michelle Taub, Allison M. Banzon, Tom Zhang & Zhongzhou Chen - 2022 - Frontiers in Psychology 13:813514.
    Success in online and blended courses requires engaging in self-regulated learning (SRL), especially for challenging STEM disciplines, such as physics. This involves students planning how they will navigate course assignments and activities, setting goals for completion, monitoring their progress and content understanding, and reflecting on how they completed each assignment. Based on Winne & Hadwin’s COPES model, SRL is a series of events that temporally unfold during learning, impacted by changing internal and external factors, such as goal orientation and content (...)
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  38. Defining agency: Individuality, normativity, asymmetry, and spatio-temporality in action.Xabier Barandiaran, E. Di Paolo & M. Rohde - 2009 - Adaptive Behavior 17 (5):367-386.
    The concept of agency is of crucial importance in cognitive science and artificial intelligence, and it is often used as an intuitive and rather uncontroversial term, in contrast to more abstract and theoretically heavy-weighted terms like “intentionality”, “rationality” or “mind”. However, most of the available definitions of agency are either too loose or unspecific to allow for a progressive scientific program. They implicitly and unproblematically assume the features that characterize agents, thus obscuring the full potential and challenge of modeling agency. (...)
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  39.  6
    Self-Regulation of Slippery Deadlines: The Role of Procrastination in Work Performance.Piers Steel, Daphne Taras, Allen Ponak & John Kammeyer-Mueller - 2022 - Frontiers in Psychology 12.
    We investigated the causes and impact of procrastination on “slippery deadlines,” where the due date is ill-defined and can be autonomously extended, using the unique applied setting of grievance arbitration across two studies. In Study One, using 3 years of observed performance data derived from Canadian arbitration cases and a survey of leading arbitrators, we examined the effect of individual differences, self-regulatory skills, workloads and task characteristics on time delay. Observed delay here is a critical criterion, where justice is emphasized (...)
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  40.  20
    Proteolytic control in ciliogenesis: Temporal restriction or early initiation?Gregor Habeck & Jörg Schweiggert - 2022 - Bioessays 44 (9):2200087.
    Cellular processes are highly dependent on a dynamic proteome that undergoes structural and functional rearrangements to allow swift conversion between different cellular states. By inducing proteasomal degradation of inhibitory or stimulating factors, ubiquitylation is particularly well suited to trigger such transitions. One prominent example is the remodelling of the centrosome upon cell cycle exit, which is required for the formation of primary cilia – antenna‐like structures on the surface of most cells that act as integrative hubs for various extracellular signals. (...)
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  41. Consciousness and Self-Regulation.Frederic Peters - 2009 - Journal of Mind and Behavior 30 (4):267.
    The mystery surrounding consciousness as subjectivity dissipates dramatically when understood in its biological context. The core characteristics of consciousness can be seen to derive from its functionality, and the fundamental function of cognition, given the equivalence of mental activity and brain process, is to advance the survival and thus the self-regulative capacity of the organism of which the brain is a part. These core elements of consciousness are comprised of a self-locational data structure which serves to configure ongoing experience in (...)
     
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  42.  18
    Vasa, a regulator of localized mRNA translation on the spindle.Paola Alejandra Sundaram Buitrago, Kavya Rao & Mamiko Yajima - 2023 - Bioessays 45 (4):2300004.
    Localized mRNA translation is a biological process that allows mRNA to be translated on‐site, which is proposed to provide fine control in protein regulation, both spatially and temporally within a cell. We recently reported that Vasa, an RNA‐helicase, is a promising factor that appears to regulate this process on the spindle during the embryonic development of the sea urchin, yet the detailed roles and functional mechanisms of Vasa in this process are still largely unknown. In this review article, to (...)
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  43.  19
    From Early Micro-Temporal Interaction Patterns to Child Cortisol Levels: Toward the Role of Interactive Reparation and Infant Attachment in a Longitudinal Study.Mitho Müller, Anna-Lena Zietlow, Nathania Klauser, Christian Woll, Nora Nonnenmacher, Edward Tronick & Corinna Reck - 2022 - Frontiers in Psychology 12.
    Parental mental disorders increase the risk for insecure attachment in children. However, the quality of caregiver–infant interaction plays a key role in the development of infant attachment. Dyadic interaction is frequently investigated via global scales which are too rough to uncover micro-temporal mechanisms. Prior research found that the latency to reparation of uncoordinated dyadic states is associated with infant behavioral and neuroendocrine regulation. We investigated the hypothesis that this interactive mechanism is critical in predicting secure vs. insecure attachment (...)
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  44.  46
    The relation between rumination and temporal features of emotion intensity.Maxime Résibois, Elise K. Kalokerinos, Gregory Verleysen, Peter Kuppens, Iven Van Mechelen, Philippe Fossati & Philippe Verduyn - 2017 - Cognition and Emotion 32 (2):259-274.
    Intensity profiles of emotional experience over time have been found to differ primarily in explosiveness and accumulation. However, the determinants of these temporal features remain poorly understood. In two studies, we examined whether emotion regulation strategies are predictive of the degree of explosiveness and accumulation of negative emotional episodes. Participants were asked to draw profiles reflecting changes in the intensity of emotions elicited either by negative social feedback in the lab or by negative events in daily life. In (...)
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  45.  24
    Coach-Created Motivational Climate and Athletes’ Adaptation to Psychological Stress: Temporal Motivation-Emotion Interplay.Montse C. Ruiz, Claudio Robazza, Asko Tolvanen, Saara Haapanen & Joan L. Duda - 2019 - Frontiers in Psychology 10:439494.
    This two-wave study investigated the temporal interplay between motivation and the intensity and reported impact of athletes’ emotions in training settings. In total, 217 athletes completed self-report measures of motivational climate, motivation regulations, emotional states (i.e., pleasant states, anger, and anxiety) experienced before practice at two time points during a 3-month period. Latent change score modeling revealed significantly negative paths from task-involving climate at time 1 to the latent change in the intensity of dysfunctional anxiety and anger, and significantly (...)
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  46.  61
    Expanding the Temporal Dimensions of Developmental Biology: The Role of Environmental Agents in Establishing Adult-Onset Phenotypes.Scott F. Gilbert - 2011 - Biological Theory 6 (1):65-72.
    Developmental biology is expanding into several new areas. One new area of study concerns the production of adult-onset phenotypes by exposure of the fetus or neonate to environmental agents. These agents include maternal nutrients, developmental modulators (endocrine disruptors), and maternal care. In all three cases, a major mechanism for the generation of the altered phenotype is chromatin modification. Nutrient conditions, developmental modulators, and even maternal care appear to alter DNA methylation and other associated changes in chromatin that regulate gene expression. (...)
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  47.  36
    Safety by simulation: theorizing the future of robot regulation.Mika Viljanen - 2024 - AI and Society 39 (1):139-154.
    Mobility robots may soon be among us, triggering a need for safety regulation. Robot safety regulation, however, remains underexplored, with only a few articles analyzing what regulatory approaches could be feasible. This article offers an account of the available regulatory strategies and attempts to theorize the effects of simulation-based safety regulation. The article first discusses the distinctive features of mobility robots as regulatory targets and argues that emergent behavior constitutes the key regulatory concern in designing robot safety (...)
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  48.  44
    Illness Perceptions of COVID-19 in Europe: Predictors, Impacts and Temporal Evolution.David Dias Neto, Ana Nunes da Silva, Magda Sofia Roberto, Jelena Lubenko, Marios Constantinou, Christiana Nicolaou, Demetris Lamnisos, Savvas Papacostas, Stefan Höfer, Giovambattista Presti, Valeria Squatrito, Vasilis S. Vasiliou, Louise McHugh, Jean-Louis Monestès, Adriana Baban, Javier Alvarez-Galvez, Marisa Paez-Blarrina, Francisco Montesinos, Sonsoles Valdivia-Salas, Dorottya Ori, Raimo Lappalainen, Bartosz Kleszcz, Andrew Gloster, Maria Karekla & Angelos P. Kassianos - 2021 - Frontiers in Psychology 12.
    Objective: Illness perceptions are important predictors of emotional and behavioral responses in many diseases. The current study aims to investigate the COVID-19-related IP throughout Europe. The specific goals are to understand the temporal development, identify predictors and examine the impacts of IP on perceived stress and preventive behaviors.Methods: This was a time-series-cross-section study of 7,032 participants from 16 European countries using multilevel modeling from April to June 2020. IP were measured with the Brief Illness Perception Questionnaire. Temporal patterns (...)
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  49.  17
    The legal relevance of a minor patient’s wish to die: a temporality-related exploration of end-of-life decisions in pediatric care.Jozef H. H. M. Dorscheidt - 2023 - History and Philosophy of the Life Sciences 45 (1):1-24.
    Decisions regarding the end-of-life of minor patients are amongst the most difficult areas of decision-making in pediatric health care. In this field of medicine, such decisions inevitably occur early in human life, which makes one aware of the fact that any life—young or old—cannot escape its temporal nature. Belgium and the Netherlands have adopted domestic regulations, which conditionally permit euthanasia and physician-assisted suicide in minors who experience hopeless and unbearable suffering. One of these conditions states that the minor involved (...)
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  50.  28
    The Efficacy of Downward Counterfactual Thinking for Regulating Emotional Memories in Anxious Individuals.Natasha Parikh, Felipe De Brigard & Kevin S. LaBar - 2022 - Frontiers in Psychology 12.
    Aversive autobiographical memories sometimes prompt maladaptive emotional responses and contribute to affective dysfunction in anxiety and depression. One way to regulate the impact of such memories is to create a downward counterfactual thought–a mental simulation of how the event could have been worse–to put what occurred in a more positive light. Despite its intuitive appeal, counterfactual thinking has not been systematically studied for its regulatory efficacy. In the current study, we compared the regulatory impact of downward counterfactual thinking, temporal (...)
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