How can we understand the world as a whole instead of separate natural and human realms? Joseph T. Rouse proposes an approach to this classic problem based on radical new conceptions of both philosophical naturalism and scientific practice.

Philosophy of science has undergone a naturalistic turn, moving away from traditional idealized concerns with the logical structure of scientific theories and toward focusing on real-world scientific practice, especially in domains such as modeling and experimentation. As part of this shift, recent work has explored how the project of philosophically understanding science as a natural phenomenon can be enriched by drawing from different fields and disciplines, including niche construction theory in evolutionary biology, on the one hand, and ecological (...) and enactive views in embodied cognitive science, on the other. But these insights have so far been explored in separation from each other, without clear indication of whether they can work together. Moreover, the focus on particular practices, however insightful, has tended to lack consideration of potential further implications for a naturalized understanding of science as a whole (i.e., above and beyond those particular practices). Motivated by these developments, here we sketch a broad-ranging view of science, scientific practice and scientific knowledge in terms of ecological-enactive co-construction. The view we propose situates science in the biological, evolutionary context of human embodied cognitive activity aimed at addressing the demands of life. This motivates reframing theory as practice, and reconceptualizing scientific knowledge in ecological terms, as relational and world-involving. Our view also brings to the forefront of attention the fundamental link between ideas about the nature of mind, of science and of nature itself, which we explore by outlining how our proposal differs from more conservative, and narrower, conceptions of “cognitive niche construction.”. (shrink)

This article is concerned with the relationship between scientific practice and the metaphysics of laws of nature and natural properties. I begin by examining an argument by Michael Townsen Hicks and Jonathan Schaffer that an important feature of scientific practice—namely, that scientists sometimes invoke non-fundamental properties in fundamental laws—is incompatible with metaphysical theories according to which laws govern. I respond to their argument by developing an epistemology for governing laws that is grounded in scientific practice. This epistemology (...) is of general interest for non-Humean theories of laws, for it helps to explain our epistemic access to non-Humean theoretical entities such as governing laws or fundamental powers. (shrink)

German medical schools have not yet sufficiently introduced students to the field of good scientific practice. In order to prevent scientific misconduct and to foster scientific integrity, courses on GSP must be an integral part of the curriculum of medical students. Based on a review of the literature, teaching units and materials for two courses on GSP were developed and tested in a pilot course. The pilot course was accompanied by a pre-post evaluation that assessed students’ knowledge (...) and attitudes towards scientific integrity and scientific misconduct. A syllabus was designed that comprised the following six topics: theoretical foundations of GSP; scientific publishing; empirical data; scientific supervision and teamwork; clinical research; personal interests. The comparison pre versus post-intervention yielded statistically significant changes in regard to the participants’ knowledge and attitude toward all forms of scientific misconduct treated in the course. As the majority of participants was not familiar with the fundamental regulations or guidelines of GSP, it seems crucial to train students in actively applying such norms to real-world conflicts. Students’ unfamiliarity with the fundamentals of GSP can be linked to the fact that many students have already experienced forms of scientific misconduct. Thus, GSP syllabi should be closely adjusted to a student’s realm of experience. All in all, courses on GSP can be seen as a potential means to increase the number of young scholars. (shrink)

The theory of concepts advanced in the present discussion aims at accounting for a) how a concept makes successful practice possible, and b) how a scientific concept can be subject to rational change in the course of history. To this end, I suggest that each scientific concept consists of three components of content: 1) the concept.

In this paper I examine Paul Thagard's computational approach to studying science, which is a contribution to the cognitive science of science. I present several criticisms of Thagard's approach and use them to motivate some suggestions for alternative approaches in cognitive science of science. I first argue that Thagard does not clearly establish the units of analysis of his study. Second, I argue that Thagard mistakenly applies the same model to both individual and group decision making. Finally, I argue that (...) in attempting to account for psychological and social processes as well as providing a philosophical model of successful reasoning Thagard attempts to explain too much with one model, thus straining the plausibility of his model. (shrink)

This monograph investigates the collaborative creation of scientific knowledge in research groups. To do so, I combine philosophical analysis with a first-hand comparative case study of two research groups in experimental science. Qualitative data are gained through observation and interviews, and I combine empirical insights with existing approaches to knowledge creation in philosophy of science and social epistemology. -/- On the basis of my empirically-grounded analysis I make several conceptual contributions. I study scientific collaboration as the interaction of (...) scientists within research groups. Thereby, I argue that research groups and their role in scientific practice deserve more philosophical attention than they have hitherto received. In contemporary natural science, research groups are key to the formulation and corroboration of scientific knowledge claims prior to their publication. Specifically, I suggest epistemic difference and the porosity of social structure as two conceptual leitmotifs in the study of group collaboration. With epistemic difference, I emphasize the value of socio-cognitive heterogeneity in group collaboration. With porosity, I underline the fact that a research group as social structure does not entirely contain the inter-individual efforts necessary to formulate and corroborate knowledge claims. -/- In my analysis of research groups, I focus on the division of epistemic labor among group members. Through their complementary collaborative efforts single scientists engage in relations of mutual epistemic dependence. To deepen philosophy’s understanding of scientific practice in its diversity, a distinction should be made between opaque and translucent epistemic dependence. While opaque epistemic dependence involves asymmetries in expertise, translucent epistemic dependence does not. As epistemic dependence is facilitated by trust, I investigate the dynamics of epistemic trust in group collaboration. Trust among collaborating scientists is inherently incomplete, and I show that scientists make use of diverse strategies to increase and to supplement personal trust. Based on my reflections on trust and dependence, I give an account of the relation between individual knowing and collaboratively created knowledge in research groups. Together these investigations contribute to the discussion of philosophical methodology in the study of scientific practice and promote the use of empirical methods. (shrink)

Philosophers, historians, and sociologists of science have grown interested in the daily practices of scientists. Recent studies have drawn linkages between scientific innovations and more ordinary procedures, craft skills, and sources of sponsorship. These studies dispute the idea that science is the application of a unified method or the outgrowth of a progressive history of ideas. This book critically reviews arguments and empirical studies in two areas of sociology that have played a significant role in the 'sociological turn' (...) in science studies: ethnomethodology and the sociology of scientific knowledge. In both fields, efforts to study scientific practices have led to intractable difficulties and debates, due in part to scientistic and foundationalist commitments that remain entrenched with social-scientific research policies and descriptive language. The central purpose of this book is to explore the possibility of an empirical approach to the epistemic contents of science that avoids the pitfalls of scientism and foundationalism. (shrink)

Introduction : towards philosophy of scientific practice -- The origin of the concept of practice -- Scientific practice: significance, types and scopes -- The nature of scientific practice -- The nature of knowledge : the local knowledge -- Knowledge and power -- The contextual normativity of scientific practice -- Philosophy of scientific practice and naturalism (I) -- Philosophy of scientific practices and naturalism (II) -- Philosophy of scientific practice and relativism -- Partner (...) of philosophy of scientific practice : philosophy of scientific experimentation -- New empiricism : close relative of philosophy of scientific practice -- The starting point of scientific research: opportunity, question, or observation? -- New solution for the old problem : the relationship among observation, experiment and theory -- New studies on replicability of scientific experiment -- Local knowledge (I) : traditional chinese medicine (TCM) -- Local knowledge (II) : chinese theory of fengshui -- Local knowledge (III) : ethnobotany -- Conclusion : scientific practice in ongoing and unlimited process. (shrink)

In this paper I will introduce a problem for at least those Humeans who believe that the future is open. More particularly, I will argue that the following aspect of scientific practice cannot be explained by openfuture- Humeanism: There is a distinction between states that we cannot bring about (which are represented in scientific models as nomologically impossible) and states that we merely happen not to bring about. Open-future-Humeanism has no convincing account of this distinction. Therefore it fails (...) to explain why we cannot bring about certain states of affairs, it cannot explain what I call the “recalcitrance of nature”. (shrink)

In the last few decades, philosophy of science has increasingly focused on multilevel models and causal mechanistic explanations to account for complex biological phenomena. On the one hand, biological and biomedical works make extensive use of mechanistic concepts; on the other hand, philosophers have analyzed an increasing range of examples taken from different domains in the life sciences to test—support or criticize—the adequacy of mechanistic accounts. The article highlights some challenges in the elaboration of mechanistic explanations with a focus on (...) cancer research and neuropsychiatry. It jointly considers fields, which are usually dealt with separately, and keeps a close eye on scientific practice. The article has a twofold aim. First, it shows that identification of the explananda is a key issue when looking at dynamic processes and their implications in medical research and clinical practice. Second, it discusses the relevance of organizational accounts of mechanisms, and questions whether thorough self-sustaining mechanistic explanations can actually be provided when addressing cancer and psychiatric diseases. While acknowledging the merits of the wide ongoing debate on mechanistic models, the article challenges the mechanistic approach to explanation by discussing, in particular, explanatory and conceptual terms in the light of stances from medical cases. (shrink)

This is a review of Marc Lange's _Natural Laws in Scientific Practice<D>.

The method of metaphysics of scientific practice consists in developing metaphysical claims on the basis of empirical information from and about scientific practice. This method stands in the tradition of naturalistic or scientific metaphysics on the one hand, and philosophy of science in practice on the other. In this chapter we draw on some of our own research to specify the method at work. We argue that the method is typically carried out in four steps: identifying the (...) available empirical information that might be relevant to the metaphysical topic of interest; selecting the relevant empirical information; developing a preliminary metaphysical claim that the relevant empirical information supports; mutually adjusting empirical information and metaphysics. We reveal some major methodological challenges and present ways to overcome them. We conclude that when drawing metaphysical claims from scientific practicewe need to: first, make sure that our previous metaphysical views do not influence the empirical information or its selection in problematic ways; second, explain in what sense we are doing metaphysics, countering for instance the idea that metaphysical claims must be highly general and transdisciplinary. We end the chapter by pointing to the advantages of the method of metaphysics of scientific practice. (shrink)

In the recent philosophical literature, several counterexamples to the interpretative principle that symmetry-related models are physically equivalent have been suggested The Oxford handbook of philosophy of physics, Oxford University Press, Oxford, 2013, Noûs 52:946–981, 2018; Fletcher in Found Phys 50:228–249, 2020). Arguments based on these counterexamples can be understood as arguments from scientific practice of roughly the following form: because in scientific practice such-and-such symmetry-related models are treated as representing distinct physical situations, these models indeed represent distinct physical (...) situations. In this paper, a strategy for analysing arguments of this type is presented and applied to the examples that can be found in the literature. I argue that if we are exclusively interested in models understood as representing entire possible worlds, arguments from scientific practice should involve some additional assumptions to guarantee they are relevant for models understood in this way. However, none of the examples presented in the literature satisfy all these additional assumptions, which leads to the conclusion that arguments from scientific practice based on these examples do not undermine the interpretative principle that different symmetry-related models represent the same possible world. (shrink)

“We can avoid, above all, the mistake of thinking that unless one is big one is negligible.”This paper tries to think about the contexts of scientific practices in peripheral spaces, spaces that exist outside the domain of the resource-rich and well-established scientific communities. I ask the question whether contributions from such modest circumstances can give rise to any creative expertise that is capable of producing novel outcomes in science, and whether exploring such contexts might give us reasons (...) for changing our current mental model of what we take science to be. I assume, of course, that scientific thinking can be present in modest as well as in resource-rich circumstances, and little-known episodes... (shrink)

Scientific knowledge is the outcome of a collective, for example, of experts, methods, equipment, and experimental sites. The configuration of the collective shapes the scientific findings, allowing some interactions to become visible and meaningful at the expense of others. PROTEE is a methodology that aims to increase the reflexivity of research and innovation projects by helping to sensitize practitioners to the demarcations their projects enact and to think through how these may affect the relevance of the outcomes. We (...) used PROTEE to structure a series of dialogues with a research project that wanted its findings to make a contribution to the heated debate on transgenic trees. Through this process, the project did indeed become more articulated while we ourselves became engaged with the project in a very particular way, by becoming loyal to it. The dialogues also made the risks that engagement with public debate entails for scientists very apparent. Like us, the scientific project chose its loyalties, but what PROTEE did was to help make these explicit. (shrink)

It is often presumed that the laws of nature have special significance for scientific reasoning. But the laws' distinctive roles have proven notoriously difficult to identify--leading some philosophers to question if they hold such roles at all. This study offers original accounts of the roles that natural laws play in connection with counterfactual conditionals, inductive projections, and scientific explanations, and of what the laws must be in order for them to be capable of playing these roles. Particular attention (...) is given to laws of special sciences, levels of scientific explanation, natural kinds, ceteris-paribus clauses, and physically necessary non-laws. (shrink)

Metaphysical presuppositions are important for guiding scientific practices and research. The success of twentieth-century biology, for instance, is largely attributable to presupposing that complex biological processes are reducible to elementary components. However, some biologists have challenged the sufficiency of reductionism for investigating complex biological phenomena and have proposed alternative presuppositions like organicism. In this article, contemporary cancer research is used as a case study to explore the importance of metaphysical presuppositions for guiding research. The predominant paradigm directing cancer (...) research is the somatic mutation theory, in which mutated genes are presumed to be ultimately responsible for explaining carcinogenesis. This reductionistic approach to cancer has been criticised recently, and an organistic approach has been proposed. The article concludes with a discussion of the reciprocal interaction of metaphysical presuppositions and scientific practices for investigating cancer's complex nature. (shrink)

What are the metaphysical commitments which best 'make sense' of our scientific practice? In this book, Andreas Hüttemann provides a minimal metaphysics for scientific practice, i.e. a metaphysics that refrains from postulating any structure that is explanatorily irrelevant. Hüttemann closely analyses paradigmatic aspects of scientific practice, such as prediction, explanation and manipulation, to consider the questions whether and what metaphysical presuppositions best account for these practices. He looks at the role which scientific generalisation play in (...) predicting, testing, and explaining the behaviour of systems. He also develops a theory of causation in terms of quasi-inertial processes and interfering factors, and he proposes an account of reductive practices that makes minimal metaphysical assumptions. His book will be valuable for scholars and advanced students working in both philosophy of science and metaphysics. (shrink)

Techno-Scientific Practices analyzes and helps readers to understand the role of instruments and technologies in the practice of science, and their partnership with human agents in producing knowledge about the world.

There are certain illocutionary acts that, contrary to John Searle's speech act theory, cannot be correctly classified as assertives. Searle's sincerity and essential conditions on assertives require, plausibly, that we believe our assertions and that we are committed to their truth. Yet it is a commonly accepted scientific practice to propose and investigate an hypothesis without believing it or being at all committed to its truth. Searle's attempt to accommodate such conjectural acts by claiming that the degree of belief (...) and of commitment expressed by some assertives “may approach or even reach zero“ is unsuccessful, since it evacuates his thesis that these are substantive necessary conditions on assertives of any force. The illocutionary acts in question are central to scientific activity and so cannot be plausibly ignored by a theory of speech acts. The problem is not limited simply to Searle's theory, since even theories which depart markedly from Searle's in other respects are often committed to similar characterizations of assertion. (shrink)

It is a common view among philosophers of science that theoretical virtues (also known as epistemic or cognitive values), such as simplicity and consistency, play an important role in scientific practice. In this article, I set out to study the role that theoretical virtues play in scientific practice empirically. I apply the methods of data science, such as text mining and corpus analysis, to study large corpora of scientific texts in order to uncover patterns of usage. These (...) patterns of usage, in turn, might shed some light on the role that theoretical virtues play in scientific practice. Overall, the results of this empirical study suggest that scientists invoke theoretical virtues explicitly, albeit rather infrequently, when they talk about models (less than 30%), theories (less than 20%), and hypotheses (less than 15%) in their published works. To the extent that they are mentioned in scientific publications, the results of this study suggest that accuracy, consistency, and simplicity are the theoretical virtues that scientists invoke more frequently than the other theoretical virtues tested in this study. Interestingly, however, depending on whether they talk about hypotheses, theories, or models, scientists may invoke one of those theoretical virtues more than the others. (shrink)

Proponents of practice-based accounts of science often reject theory-based accounts, and seek to explain scientific theory reductively in terms of practice. I consider two examples: Dimitri Ginev and Joseph Rouse. Both draw inspiration from Martin Heidegger’s existential conception of science. And both allege that Heidegger ultimately betrayed his insight that theory can be reduced to practice when he sought to explain modern science in terms of a theory-based “mathematical projection of nature.” I argue that Heidegger believed neither that theory (...) can be reduced to practice nor that the mathematical projection is theory-based. For Heidegger, the mathematical projection is the existential condition of possibility for modern science. The theory and practice of modern science represent two distinct modes of this single existential ground state. (shrink)

Assessment of error and uncertainty is a vital component of both natural and social science. This edited volume presents case studies of research practices across a wide spectrum of scientific fields. It compares methodologies and presents the ingredients needed for an overarching framework applicable to all.

My dissertation combines philosophy of science and political philosophy. Drawing directly on the work of Alasdair MacIntyre and inspired by John Dewey, I develop two rival conceptions of scientific practice. I show that these rivals are closely linked to the two basic sides in the science and values debate -- the debate over the extent to which ethical and political values may legitimately influence scientific inquiry. Finally, I start to develop an account of justice that is sensitive to (...) these legitimate and illegitimate influences. (shrink)

Both sides in the debate about scientific realism have argued that their view provides a better account of actual scientific practice. For example, it has been claimed that the practice of theory conjunction presupposes realism, and that scientists' use of multiple and incompatible models presupposes some form of instrumentalism. Assuming that the practices of science are rational, these conclusions cannot both be right. I argue that neither of them is right, and that, in fact, all scientific (...) practices are compatible with both realism and instrumentalism. I also repudiate van Fraassen's argument to the effect that the instrumentalist account of scientific practice is logically weaker, hence better, than the realist account. In the end, there are no scientific practice arguments on the table that support either side of the debate. It is also noted that the deficiencies of van Fraassen's argument are recapitulated in Putnam's miracle argument for realism. My pessimistic assessment of the state of the debate is reminiscent of Arthur Fine's. However, Fine's argument for the ‘natural ontological attitude’ once again repeats the problems of van Fraassen's and Putnam's arguments. (shrink)

This article motivates a shift in certain strands of the debate over legitimate roles for nonepistemic values in scientific practice from investigating what is involved in taking cognitive attitudes like acceptance toward an empirical hypothesis to looking at a social understanding of assertion, the act of communicating that hypothesis. I argue that speech act theory’s account of assertion as a type of doing makes salient legitimate roles nonepistemic values can play in scientific practice. The article also shows how (...) speech act theory might provide a framework for fruitfully extending aspects of the social and pragmatic turns in the philosophy of science. (shrink)

I seek to provide a systematic and comprehensive framework for the description and analysis of scientific practice—a philosophical grammar of scientific practice, ‘grammar’ as meant by the later Wittgenstein. I begin with the recognition that all scientific work, including pure theorizing, consists of actions, of the physical, mental, and ‘paper-and-pencil’ varieties. When we set out to see what it is that one actually does in scientific work, the following set of questions naturally emerge: who is doing (...) what, why, and how? More specifically, we must arrive at some coherent philosophical accounts of the following elements of scientific practice: the agent—free, embodied, and constantly in second-person interactions with other agents; the purposes and proximate aims of the agent; types of activities that the agent engages in; ontological principles necessarily presumed for the performance of particular activities; instruments and other resources that the agent pulls together for the performance of each activity. After sketching the general framework, I also give some illustrative contrasts between the more traditional descriptions of scientific practice and the kind of descriptions enabled by the proposed framework. (shrink)

Hermeneutic studies of science locate a circle at the heart of scientific practice: scientists only gain knowledge of what they, in some sense, already know. This may seem to threaten the rational validity of science, but one can argue that this circle is a virtuous rather than a vicious one. A virtuous circle is one in which research conclusions are already present in the premises, but only in an indeterminate and underdeveloped way. In order to defend the validity of (...) science, the hermeneuticist must describe a method by which a vague and confused initial knowledge of nature gets transformed into a clear and determinate knowledge of nature. I consider three such methods. The first is regressus demonstrativa, favoured by the physicians of Padua during the fifteenth and sixteenth centuries. The second is mathēsis, introduced by Martin Heidegger in his discussion of seventeenth-century science. The third is Denkstil, a key concept in Ludwik Fleck’s history of syphilology. I conclude by listing three desiderata for a hermeneutic science studies: that it be anti-metaphysical, historical, and sociological. --- Reprinted in: Erich Otto Graf, Martin Schmid & Johannes Fehr (eds.), Fleck and the Hermeneutics of Science (Collegium Helveticum Heft 14) (Zürich, 2016), pp. 85-93. (shrink)

Philosophers’ traditional emphasis on theories, theoretical modeling, and explanation misguides research in philosophy of science. Articulating and applying core theories is part of scientific practice, but it is not the essence of scientific practice. Insofar as science has an essence, it is to systematically investigate and learn about what is not yet understood. This lecture analyzes genetics to articulate a broad-practice-centered approach to philosophy of science. It concludes by arguing that this approach can lead to richer, deeper, and (...) more useful philosophies of science, philosophies that can better inform science policy and the public’s understanding of science. (shrink)

I consider the relationship between scientific practice and the philosophical debate surrounding biological individuality. I argue for the sensitivity account, on which biologists do not require a resolution to the individuality debate. This view puts me in disagreement with much of the literature on biological individuality, where it has become common to claim that there is a relationship of dependence between biologists’ conceptions of individuality and the quality of their empirical work.

It is the continuity between epistemology and empirical science that the naturalism in contemporary philosophy of science emphasizes. After its individual and social dimensions, the philosophy of scientific practice takes a stand on naturalism in order to observe complex scientific activities through practice. However, regarding the naturalism’s problem of normativity, the philosophy of scientific practice today has deconstructed more than it has constructed.

What things count as individuals, and how do we individuate them? It is a classic philosophical question often tackled from the perspective of analytic metaphysics. This volume proposes that there is another channel by which to approach individuation -- from that of scientific practices. From this perspective, the question then becomes: How do scientists individuate things and, therefore, count them as individuals? This volume collects the work of philosophers of science to engage with this central philosophical conundrum from (...) a new angle, highlighting the crucial topic of experimental individuation and building upon recent, pioneering work in the philosophy of science. An introductory chapter foregrounds the problem of individuation, arguing it should be considered prior to the topic of individuality. The following chapters address individuation and individuality from a variety of perspectives, with prominent themes being the importance of experimentation, individuation as a process, and pluralism in individuation's criteria. Contributions examine individuation in a wide range of sciences, including stem cell biology, particle physics, and community ecology. Other chapters examine the metaphysics of individuation, its bearing on realism/antirealism debates, and interrogate epistemic aspects of individuation in scientific practice. In exploring individuation from the philosophy of biology, physics, and other scientific subjects, this volume ultimately argues for the possibility of several criteria of individuation, upending the tenets of traditional metaphysics. It provides insights for philosophers of science, but also for scientists interested in the conceptual foundations of their work. (shrink)

In his early work on the problem of coordination, Hans Reichenbach introduced axioms of coordination to describe the relationship between theory and observation. His insistence that these axioms are determinable a priori, however, causes him to ignore the normative dimensions of scientific inquiry and, in turn, generates a misleading interpretation of the theory-observation relationship. In response, I propose an alternative approach that describes this relationship through the framework of scientific practices. My argument will draw on two examples (...) that have not been explored by the philosophical literature in the context of coordination problems: the clinical definition of death and Stanley Prusiner’s prion hypothesis. (shrink)

It is my aim in this paper to look at some of the arguments that are brought forward for or against certain claims to unity/disunity (in particular to examine those arguments from science and from scientific practice) in order to evaluate whether they really show what they claim to. This presupposes that the concept or rather the concepts of the unity of physics are reasonably clear. Three concepts of unity can be identified: (1) ontological unity, which refers to the (...) objects physics is about; (2) descriptive unity, which addresses the descriptive devices physics employs in dealing with physical systems (3) unity of practice, which deals with what physicists actually do. (shrink)

In diesem Aufsatz wird der jeweils mögliche Beitrag verschiedener Experten, insbesondere von Fachphilosophen und Naturwissenschaftlern, zu einer allgemeinen Diskussion derjenigen ethischen und rechtlichen Fragen erörtert, die sich in Verbindung mit dem Genomprojekt stellen. Wir kommen zu dem Ergebnis, daß man die tatsächlich schon betriebene Forschung keinesfalls wird aufhalten können, sondern allenfalls bestimmte für bedenklich gehaltene Anwendungen der neuen Techniken verzögern oder verhindern kann. Wir stellen verschiedene Probleme vor, die die Wirksamkeit der philosophischen Reflexion in solchen Fragen zweifelhaft erscheinen läßt, die (...) mit der grundsätzlichen Unzulänglichkeit der traditionellen Verfahren angewandter Ethik, aber auch mit der Pluralität der Grundnormen in einer modernen Gesellschaft zu tun haben. So fällt der empirischen Wissenschaft eine entscheidende Rolle bei der Beurteilung der Angemessenheit bestimmter Verfahren im Hinblick auf die eine Norm zu, die allgemein vorausgesetzt werden darf, nämlich die über die Bedeutung des handgreiflichen Eigeninteresses, da dieses am ehesten in der Lage ist, die voraussichtlichen Möglichkeiten und Gefahren einer bestimmten Technik einzuschätzen. Wir behaupten, daß die bisherigen Erfahrungen mit anderen Organismen innerhalb und vor allem außerhalb von Laborato-rien auf eine Komplexität der Interaktionen der Gene untereinander und der genetischen Erbmasse mit der Umgebung hindeuten, die eine Vorhersage des Resultats beim Menschen als sehr ungewiß erscheinen läßt. Angesichts dieser Ungewißheit einerseits und des entgegengesetzten finanziellen Interesses seitens des Anbieters der neuen Techniken andererseits mag das amerikanische Zivilrecht vielleicht den stärksten Anreiz für den Anbieter darstellen, die Risiken realistisch einzuschätzen und bei der Anwendung mit der angemessenen Vorsicht zu Werke zu gehen. Noch wirksamer als jeglicher moralischer Appell mögen die finanziellen Gefahren für den überoptimistischen Anbieter sein, die Menschen als seine "Kunden" vor Schaden zu bewahren. Schließlich weisen wir auf die Schwierigkeit der Kommunikation der Ergebnisse philosophischer und wissenschaftlicher Überlegungen im Zeitalter der Massenmedien hin. Die Rationalität der Diskussion muß soweit wie möglich allererst hergestellt werden, statt daß man sie voraussetzen könnte. Dafür ist eine der größten Gefahren die Einbindung der modernen Naturwissenschaft gerade in die Industrien, deren Leistungen oder Risiken sie eigentlich beurteilen soll. (shrink)

Rouse’s masterful tome encompasses capacious domains but suffers from obscuration due to pleonasm and too many attempts to counter or unify the disparate views of too many other distinguished philosophers.

According to van Fraassen, constructive empiricism (CE) makes better sense of scientific activity than scientific realism (SR). I discuss a recent episode in biomedical research - investigations about Helicobacter Pylori and its relation to peptic ulcer. CE's expedient to cope with it is a sort of belief substitution. I argue that replacing realist beliefs by empiricist surrogates (as-if beliefs) could accommodate scientists' expectations and behavior. Nonetheless, theoretical agnosticism could hardly motivate scientists to focus just on the observational consequences (...) derived from the theory at issue. Contrary to van Fraassen, I conclude then that, concerning scientific practice, realist beliefs cannot be considered as a gratuitious surplus which should be rejected. (shrink)

Discussions over whether these natural kinds exist, what is the nature of their existence, and whether natural kinds are themselves natural kinds aim to not only characterize the kinds of things that exist in the world, but also what can knowledge of these categories provide. Although philosophically critical, much of the past discussions of natural kinds have often answered these questions in a way that is unresponsive to, or has actively avoided, discussions of the empirical use of natural kinds and (...) what I dub “activities of natural kinding” and “natural kinding practices”. The natural kinds of a particular discipline are those entities, events, mechanisms, processes, relationships, and concepts that delimit investigation within it—but we might reasonably ask: How are these natural kinds discovered?, How are they made?, Are they revisable?, and Where do they come from? A turn to natural kinding practices reveals a new set of questions open for investigation: How do natural kinds explain through practice?, What are natural kinding practices and classifications and why should we care?, What is the nature of natural kinds viewed as a set of activities?, and How do practice approaches to natural kinds shape and reconfigure scientific disciplines? Natural kinds have traditionally been discussed in terms of how they classify the contents of the world. The metaphysical project has been one which identifies essences, laws, sameness relations, fundamental properties, and clusters of family resemblances and how these map out the ontological space of the world. But actually how this is done has been less important in the discussion than the resultant categories that are produced. I aim to rectify these omissions and suggest a new metaphysical project investigating kinds in practice. (shrink)

The longstanding philosophical orthodoxy on counterfactuals holds, in part, that counterfactuals with metaphysically impossible antecedents are indiscriminately vacuously true. Drawing on a number of examples from across scientific practice, I argue that science routinely treats counterpossibles as non-vacuously true and also routinely treats other counterpossibles as false. In fact, the success of many central scientific endeavors requires that counterpossibles can be non-vacuously true or false. So the philosophical orthodoxy that counterpossibles are indiscriminately vacuously true is inconsistent with (...) class='Hi'>scientific practice. I argue that this provides a conclusive reason to reject the orthodoxy. (shrink)

The present paper argues that ‘mature mathematical formalisms’ play a central role in achieving representation via scientific models. A close discussion of two contemporary accounts of how mathematical models apply—the DDI account (according to which representation depends on the successful interplay of denotation, demonstration and interpretation) and the ‘matching model’ account—reveals shortcomings of each, which, it is argued, suggests that scientific representation may be ineliminably heterogeneous in character. In order to achieve a degree of unification that is compatible (...) with successful representation, scientists often rely on the existence of a ‘mature mathematical formalism’, where the latter refers to a—mathematically formulated and physically interpreted—notational system of locally applicable rules that derive from (but need not be reducible to) fundamental theory. As mathematical formalisms undergo a process of elaboration, enrichment, and entrenchment, they come to embody theoretical, ontological, and methodological commitments and assumptions. Since these are enshrined in the formalism itself, they are no longer readily obvious to either the novice or the proficient user. At the same time as formalisms constrain what may be represented, they also function as inferential and interpretative resources. (shrink)

A certain order or stability of nature has often been seen as a necessary presupposition of many of our scientific practices, in particular of our use of information gained in one kind of circumstance to explain or predict what happens in quite different situations. John Maynard Keynes and, more recently, Nancy Cartwright have argued that these practices commit us to the existence of stable ‘atoms’ or ‘natures’ or ‘tendencies.’ The phenomena we observe in nature are, on this (...) view, the result of superimposing the invariable, context-independent effects of all the different tendencies involved. (shrink)