The nature of the relationship between mind and body is one of the greatest remaining mysteries. As such, the historical origin of the current dominant belief that mind is a function of the brain takes on especial significance. In this article I aim to explore and explain how and why this belief emerged in early 19th-century Britain. Between 1815 and 1819 two brain-based physiologies of mind were the subject of controversy and debate in Britain: the system of phrenology devised by (...) Franz Joseph Gall, and William Lawrence’s lectures at the Royal College of Surgeons. Both owed a profound intellectual debt to continental comparative anatomy. In the final quarter of the 18th-century, Johann Friedrich Blumenbach, Petrus Camper and Johann Gottfried von Herder had broken away from the traditional doctrine of the Great Chain of Being by allowing for a clear anatomical distinction between ‘man’ and beast based on the morphology of the skull. This reconceptualization of man as an anatomically distinct being gave Gall and Lawrence grounds to propose that the peculiarities of the human mind were dependent on mankind’s unique cerebral size and structure. (shrink)

Kant’s analysis of the concept of natural purpose in the Critique of judgment captured several features of organisms that he argued warranted making them the objects of a special field of study, in need of a special regulative teleological principle. By showing that organisms have to be conceived as self-organizing wholes, epigenetically built according to the idea of a whole that we must presuppose, Kant accounted for three features of organisms conflated in the biological sciences of the period: adaptation, functionality (...) and conservation of forms..Kant’s unitary concept of natural purpose was subsequently split in two directions: first by Cuvier’s comparative anatomy, that would draw on the idea of adaptative functions as a regulative principle for understanding in reconstituting and classifying organisms; and then by Goethe’s and Geoffroy’s morphology, a science of the general transformations of living forms. However, such general transformations in nature, objects of an alleged ‘archaeology of nature’, were thought impossible by Kant in the §80 of the Critique of judgment. Goethe made this ‘adventure of reason’ possible by changing the sense of ‘explanation’: scientific explanation was shifted from the investigation of the mechanical processes of generation of individual organisms to the unveiling of some ideal transformations of types instantiated by those organisms. (shrink)

ArgumentHere I analyze the anatomical thought of the French physician and naturalist Félix Vicq d'Azyr (1748–1794) in order to bring to light its importance in the development of comparative anatomy at the end of the eighteenth century. I argue that his work and career can be understood as an ambitious program for a radical reform of all biomedical sciences and a reorganization of this whole field around comparative anatomy, on the conceptual as well as the institutional (...) level. In particular, he recommended a close connection between anatomical and physiological studies, and a generalization of the comparative approach towards organs and functions in man and animals. This conception led him not only to reform the scope, the methods, the style of description, and the vocabulary in anatomy, but also to construct a new classification of living beings and to pursue a quest for laws of organization. This strategy was successful, since Vicq d'Azyr was able to promote his thought as well as his institutional position efficiently. The Revolution and his untimely death prevented him from achieving his program, but his attempt would serve as an example for younger scientists like Cuvier. (shrink)

ArgumentThis paper aims to understand the emergence of comparative anatomy in the eighteenth century in the Parisian Académie Royale des Sciences. As early as the 1670s, a program centered on animal anatomy was conceived, which was a first attempt to give some autonomy to studies on animals and to link anatomy with natural history, but it declined after 1690. However, a variety of studies on animals was published in theMémoiresof the Académie during the eighteenth century. We (...) propose a descriptive typology of them in order to explore the status of animals and the significance of anatomy in each type, and to determine, in particular, which elements of Perrault's program were passed on at the Académie throughout the century. We discuss the influence of this legacy on the development of comparative anatomy after 1750, especially in Daubenton's work. (shrink)

This chapter examines Goethe’s notion of the “economy of nature [Ökonomie der Natur]” to argue that his morphological writings play a more extensive role in the formation of evolutionary science than scholars have previously acknowledged. I suggest that Goethe’s economic analogy replaces the Newtonian model of force with an experimental conception of the formative drive, opening a large-scale programme of research. This feature of his work was rightly picked up by his early critics and yet was overlooked by later biologists (...) given the emphasis on population genetics following the Modern Synthesis. Goethe’s economic analogy marks an important advance in the study of organic form, I conclude, for it places comparative anatomy within a biodynamic system of exchange. (shrink)

Morphology is the science of form. The word is used in various scientific disciplines, e.g. in geography, linguistics, etc., but it is most frequently employed to denote that part of Biology which deals with the forms of organisms. The mere description of spatial relations, however, scarcely constitutes a science. It may be hard to say by what property science is distinguished from other human endeavors, but that factual description does not suffice is generally admitted. To establish relations between facts may (...) be taken as a preliminary answer. It would still remain to define these relations. The answer to that question, however, depends largely on the particular brand of philosophy to which an author happens to subscribe. Most answers have been formulated by focusing attention largely on physics and related sciences. (shrink)

This paper investigates conceptions of explanation, teleology, and analogy in the works of Immanuel Kant (1724-1804) and Georges Cuvier (1769-1832). Richards (2000, 2002) and Zammito (2006, 2012, 2018) have argued that Kant’s philosophy provided an obstacle for the project of establishing biology as a proper science around 1800. By contrast, Russell (1916), Outram (1986), and Huneman (2006, 2008) have argued, similar to suggestions from Lenoir (1989), that Kant’s philosophy influenced the influential naturalist Georges Cuvier. In this article, I wish to (...) expand on and further the work of Russell, Outram, and Huneman by adopting a novel perspective on Cuvier and considering (a) the similar conceptions of proper science and explanation of Kant and Cuvier, and (b) the similar conceptions of the role of teleology and analogy in the works of Kant and Cuvier. The similarities between Kant and Cuvier show, contrary to the interpretation of Richards and Zammito, that some of Kant’s philosophical ideas, whether they derived from him or not, were fruitfully applied by some life scientists who wished to transform life sciences into proper sciences around 1800. However, I also show that Cuvier, in contrast to Kant, had a workable strategy for transforming the life sciences into proper sciences, and that he departed from Kant’s philosophy of science in crucial respects. (shrink)

Multimodal neuroimaging provides a rich source of data for identifying brain regions associated with disease progression and aging. However, present studies still typically analyze modalities separately or aggregate voxel-wise measurements and analyses to the structural level, thus reducing statistical power. As a central example, previous works have used two quantitative MRI parameters—R2* and quantitative susceptibility —to study changes in iron associated with aging in healthy and multiple sclerosis subjects, but failed to simultaneously account for both. In this article, we propose (...) a unified framework that combines information from multiple imaging modalities and regularizes estimates for increased interpretability, generalizability, and stability. Our work focuses on joint region detection problems where overlap between effect supports across modalities is encouraged but not strictly enforced. To achieve this, we combine L1, total variation, and L2 group lasso penalties. While the TV penalty encourages geometric regularization by controlling estimate variability and support boundary geometry, the group lasso penalty accounts for similarities in the support between imaging modalities. We address the computational difficulty in this regularization scheme with an alternating direction method of multipliers optimizer. In a neuroimaging application, we compare our method against independent sparse and joint sparse models using a dataset of R2* and QS maps derived from MRI scans of 113 healthy controls: our method produces clinically-interpretable regions where specific iron changes are associated with healthy aging. Together with results across multiple simulation studies, we conclude that our approach identifies regions that are more strongly associated with the variable of interest, more accurate, and more stable with respect to training data variability. This work makes progress toward a stable and interpretable multimodal imaging analysis framework for studying disease-related changes in brain structure and can be extended for classification and disease prediction tasks. (shrink)

This paper presents a comparative analysis of three American and three European corporate failures. The first part of the analysis is based on a theoretical framework including six areas of ethical climate; tone at the top; bubble economy and market pressure; fraudulent financial reporting; accountability, control, auditing, and governance; and management compensation. The second and third parts consider the analysis of these cases from fraud perspective and in terms of firm-specific characteristics and environmental context. The research analyses shed light (...) on the fact that, despite major differences between Europe and U.S. in terms of political institutions, laws and regulations as well as managerial practices, there are significant similarities between six groups. The analysis also demonstrates that, the ethical dilemma has been coupled with ineffective boards, inefficient corporate governance and control mechanisms, distorted incentive schemes, accounting irregularities, failure of auditors, dominant CEOs, dysfunctional management behavior and the lack of a sound ethical tone at the top. Significant similarities were also observed in the analysis from the fraud triangle perspective. However, there are several major differences between the six corporate failure cases particularly with regard to ownership structure, coverage in media, and legal, regulatory and governance frameworks. This research study may have several academic and practical contributions, particularly because of multidisciplinary, international features, and comparative analyses used in the paper. (shrink)

Anatomical exhibitions, online atlases and televised dissections have recently attracted much attention and raised questions concerning the status of and the authority over the human body, the purpose of anatomical education within and outside medical schools and the methods of teaching in the digital age. I propose that for understanding the current public views of anatomy, we need to gain insight into their historical development. This article focuses on anatomies accessible to non-medical audiences in the capital of the Habsburg (...) Empire, Vienna, at the time when the city was the seat of a world-leading medical school. Anatomy at the University of Vienna was famous for its research, instruction and the abundant provision with dissectible corpses. Public anatomies were equally rich and ranged from exhibitions at the Präuscher’s Panoptikon und Anatomisches Museum , established in 1871 in the Prater amusement park, lectures on human and comparative anatomy by the university professor Carl Bernhard Brühl (1863–1890), to displays of anatomical objects at the World Exhibition in 1873. I finish by discussing a collection of letters written by the prospective ‘cadaver donors’, offering an insight into the ways in which medical encounters and anatomical knowledge informed the working-class views of their bodies. By looking at the kinds of anatomy in circulation, as well as at the participants in these exchanges, I want to illuminate the relationship between academic and public anatomies, as well as to reveal the purposes to which public anatomy served. (shrink)

The Plant Ontology (PO; http://www.plantontology.org/) is a publicly-available, collaborative effort to develop and maintain a controlled, structured vocabulary (“ontology”) of terms to describe plant anatomy, morphology and the stages of plant development. The goals of the PO are to link (annotate) gene expression and phenotype data to plant structures and stages of plant development, using the data model adopted by the Gene Ontology. From its original design covering only rice, maize and Arabidopsis, the scope of the PO has been (...) expanded to include all green plants. The PO was the first multi-species anatomy ontology developed for the annotation of genes and phenotypes. Also, to our knowledge, it was one of the first biological ontologies that provides translations (via synonyms) in non-English languages such as Japanese and Spanish. There are about 2.2 million annotations linking PO terms to over 110,000 unique data objects representing genes or gene models, proteins, RNAs, germplasm and Quantitative Traits Loci (QTLs) from 22 plant species. In this paper, we focus on the plant anatomical entity branch of the PO, describing the organizing principles, resources available to users, and examples of how the PO is integrated into other plant genomics databases and web portals. We also provide two examples of comparative analyses, demonstrating how the ontology structure and PO-annotated data can be used to discover the patterns of expression of the LEAFY (LFY) and terpene synthase (TPS) gene homologs. (shrink)

In this introduction to Nehemiah Grew's seminal 17th-century publication The Anatomy of Plants (1682), we discuss the various influences on and impacts of Grew's innovative approach to studying plant life. We offer a review of the current literature on Grew and argue for the importance of his work in its contribution to fields ranging from microscopy to agriculture and from comparative anatomy to scientific illustration. The articles included in this special issue on “The Making of The (...) class='Hi'>Anatomy of Plants” are also introduced. We make a case for Grew as a figure of great interest and relevance in our contemporary moment; as plant studies have taken hold in the humanities, historical narratives in the history of science are expanding to include more of the life sciences—a field that, as we show, Grew actively promoted and participated in throughout his tenure at the Royal Society. (shrink)

Although there are many points of continuity, there are also a number of changes in the pedagogical form of the anatomy lecture over the longue durée, over centuries of epistemic change, rather than over years or decades. The article begins with an analysis of the physical and technical arrangements of the early modern anatomy lecture, showing how these present a general underlying similarity compared to those in place today. It then goes on to consider examples of elements of (...) speech and presentation, description and illustration that are used in the biology lecture from the early modern (sixteenth to seventeenth centuries) and late modern (or contemporary) eras. The anatomy lecture thus demonstrates a basic physical and technical continuity in the classroom or theater, whereas the larger epistemic functions in which it is embedded have changed: from a descriptive, discursive function, focusing on individual organs and their physicality, to one that is more integrative, systemic and also performative in both form and content. (shrink)

The present paper analyzes the use and understanding of the homology concept across different biological disciplines. It is argued that in its history, the homology concept underwent a sort of adaptive radiation. Once it migrated from comparative anatomy into new biological fields, the homology concept changed in accordance with the theoretical aims and interests of these disciplines. The paper gives a case study of the theoretical role that homology plays in comparative and evolutionary biology, in molecular biology, (...) and in evolutionary developmental biology. It is shown that the concept or variant of homology preferred by a particular biological field is used to bring about items of biological knowledge that are characteristic for this field. A particular branch of biology uses its homology concept to pursue its specific theoretical goals. (shrink)

This chapter contains section titled: Basic Facts about Dolphins Adaptations to Living in the Water The Dolphin Brain The Human Brain The Human Brain: Summary The Dolphin Brain Compared to the Human Brain The Dolphin Brain: Summary.

On Anatomy is the shortest treatise preserved in the Hippocratic Corpus. It describes the internal configuration of the human trunk. The account is for the most part descriptive, function being largely disregarded and speculation completely eschewed. Though systematic it is unsophisticated: two orifices for ingestion are linked by miscellaneous organs, vessels, and viscera to two orifices for evacuation. There is a clear progression in two parallel sections: first, trachea to lung, lung described, location of heart, heart described, kidneys to (...) bladder, bladder described, bladder to genitals, conclusion; and second, oesophagus to belly, location of diaphragm, location of spleen, location and description of belly, belly to intestine/colon, colon to rectum and anus, conclusion. The text offers good basic topographical or regional anatomy. That the work is concerned with human anatomy is certain from the precise description of lung and liver, with features peculiar to human organs; and is corroborated by frequent references to comparative anatomy, with which familiarity is apparently assumed. Such anatomical knowledge, based on extensive observation of animals, may have been corroborated by some human dissection, perhaps of the aborted foetus or exposed infant, in conjunction with opportunistic observation of war wounded and accident victims. While the syntax is bald, telegraphic, and asyndetic, the vocabulary is recondite, and poetic. There is erratic omission of the article and recurrent use of compendious comparisons. These features suggest that Anat. may be an abridgement of a fuller and more flowery account; this hypothesis is supported by several passages where erroneous or unclear information apparently results from excessive compression or imperfect comprehension of a source. (shrink)

There are two fundamentally different approaches to innovation: incremental and radical. In Economics as Anatomy, G.M. Peter Swann argues that economics as a discipline needs both perspectives in order to create the maximum beneficial effect for the economy. Chapters explore how and why mainstream economics is very good at incremental innovation but seems uncomfortable with radical innovation. Swann argues that economics should follow the example of many other disciplines, transitioning from one field to a range of semi-autonomous sub-disciplines. In (...) this book, he compares the missing link in empirical economics to being the economic equivalent of anatomy, the basis of medical discourse. Working as a sequel to Swann's Putting Econometrics in its Place, this book will be a vital resource to those who are discontent with the state of mainstream economics, especially those actively seeking to promote change in the discipline. Students wishing to see progress in the teaching of economics will also benefit from this timely book. (shrink)

Medical schools are among the most important spaces for the history of the body. It is here that students come to know the anatomical bodies of their future patients and, through a process of cognitive and embodied practice, that the knowing bodies of future clinicians are also shaped. Practical and theoretical understandings of medicine are formed in these affective and historied buildings and in collaboration with a broad material culture of education. Medical schools are, however, both under-theorised and under-historicised. This (...) article integrates ‘materialist’ considerations of the body with Henri Lefebvre’s philosophy of space and rhythm in order to compare two markedly different spaces – the 19th-century Anatomy Department at Semmelweis University in Hungary and the mid-20th-century ‘skills laboratory’ at Maastricht University in the Netherlands. This comparison suggests that biomedical bodies are variously shaped by the agential and affective material histories present in the everyday experience of contemporary medical education. (shrink)

This paper analyzes the transformations in anatomical representation introduced by the Visible Human Project, the first complete virtual anatomy object. By comparing the process of production of book based classical anatomy with that of the Visible Human Project, the paper identifies the medium specificity of anatomical knowledge, the extent to which its powers of demonstration and analysis are conditioned by the medium in which they take place. The paper argues that anatomy can be productively thought of as (...) a kind of writing practice, in which material flesh is written into different media as traces. Because the production of such traces always involves the destruction of the body involved the paper also interrogates the biopolitical hierarchies involved in anatomical knowledge. (shrink)

Already in his lifetime, the naturalist Louis-Jean-Marie Daubenton was dramatically contrasted with his patron and collaborator on the Histoire naturelle (Natural History), Buffon figuring as stylish and prone to hypothesizing, Daubenton as narrow and unwilling to generalize. This caricatural image of Daubenton as an anti-Buffon persists even now. The purpose of this paper is to investigate the development of Daubenton's reputation and then to moderate it by showing that he was not so averse to theorizing or generalization as history has (...) made him. Evidence for this argument comes from the Histoire naturelle and from unpublished manuscripts proving that he originally planned to contribute two synthetic treatises on animal anatomy to the Histoire naturelle. Reconstituting the series as he envisaged it allows a more balanced portrait of one of the founders of comparative anatomy and a look behind the scenes of one of the eighteenth century's most important scientific publications. (shrink)

In March 1603 the mortal remains of Queen Elizabeth I, against her stated wishes, were ‘opened’ to enable their temporary preservation until arrangements for her funeral could be completed. That post-mortem office was performed by members of the Worshipful Company of Barber-Surgeons of London, to whom her father had first granted a royal warrant to retrieve executed felons from the public gallows for their ‘better learning’ through lectures in anatomical dissection. In this article, portraiture of Elizabeth that appeals to the (...) notion of her as an embodiment of the sovereign state of England is compared with a contemporary portrait of an anatomy lesson being performed by the Barber-Surgeons, drawing connections between the dissection of felons under sovereign law and the violability of the sovereign (female) body in the liminal period between her death and the delayed formalities of ascension for James I. (shrink)

It is argued that the disciplinary identity of anatomy and physiology before 1800 are unknown to us due to the subsequent creation, success and historiographical dominance of a different discipline-experimental physiology. The first of these two papers deals with the identity of physiology from its revival in the 1530s, and demonstrates that it was a theoretical, not an experimental, discipline, achieved with the mind and the pen, not the hand and the knife. The physiological work of Jean Fernel, Albrecht (...) von Haller and others is explored to prove this point. In conclusion this old physiological tradition is compared to the new experimental physiology, as practised by Francois Magendie and Pierre Flourens. (shrink)

Much of contemporary research concerning the Platonic schools of late antiquity is philological and historical in approach. This research is needed, since late antiquity is a period that has long been neglected in the historiography of philosophy, which means that many facts and documents still await examination and publication in reliable form. Much rarer is a philosophical approach to Neoplatonism based on sound historical knowledge rather than on the cliches that until recently have masked ignorance. Such an approach is proposed (...) in the present book, whose important task it is to analyze the logical and metaphysical structures that constitute Neoplatonic philosophy. Lloyd brings together and develops ideas he has explored over many years. He takes account of a very wide range of thinkers. Plotinus, Porphyry, and Proclus play a major role, of course. But many others are also considered: Simplicius, Philoponus, Damascius, Elias--the list extends to include Neoplatonists of the Byzantine period. While allowing for the differences between these philosophers, Lloyd successfully shows how they share and elaborate on certain theories which he examines systematically, bringing out the difficulties and dilemmas that these theories often contain. One might compare his approach with that of S. Gersh, whose interests however are not exclusively philosophical, and who, like Lloyd, stresses the importance of Aristotelian ideas in the constitution of Neoplatonic philosophy. (shrink)

In four compact chapters, Kant and Marx are appraised in terms of their accounts of human passivity and activity. Comparatively brief examinations of Hegel’s treatment of this theme provide a transition from Kant to Marx. The “idealism” of Kant is found to be incoherent. Contradictions abound in it. The “naturalism” of Marx is free of contradictions; it carries the day. The writer’s style is a close explication of texts. The reader does well to have the sources at his elbow.

Anatomy texts are seen as authoritative sources for knowledge about natural sex differences. The concepts of a natural, biological sex and of a natural difference are, however, increasingly difficult to sustain. A growing number of scholars have pointed to the fact that `sex' as much as `gender' is a historical and social construction. This article examines how the multiple-edition anatomy textbook, Gray's Anatomy, has portrayed the sexed body and male/female differences during the course of its publication, 1858 (...) to the present, focusing on specific parts of the anatomy, namely the sex organs or `organs of generation', the pelvis, the skull and the brain. An analysis of textual descriptions and graphic illustrations reveals that the male body has been the stable norm or standard against which the female body has been compared and implicitly judged as underdeveloped, weak or faulty. Only rarely has the male body been compared with the female body. Reflecting long-standing views about sexual complementarity and natural differences between men and women, some comparisons emphasize the reproductive functioning of females or imply that females are intellectually inferior. It would appear that the discipline of anatomy has remained largely immune from broader public debates about sexual inequality and gender representations. (shrink)

In this article, I will attempt to provide a historical case study, I suggest that the demarcation between perception and how a figure is ‘seen’ is the process of perpetual filtering between the levels of sensation and perception. I argue that this filtering operates through the basic visual principles, which may vary and have divergent functions in different paradigms. This historical case study will focus on the fifty-six plates featured in the influential work of the London surgeon William Cheselden, to (...) reveal the paradigm-based filtering in these prints by arguing that the sense data is organized in the simplest manner to view figures in their unity. Thus, I will focus on the visual principle of simplicity, which features the patterns of similarity, contrast and symmetry. An analysis of Cheselden’s usage of these patterns will demonstrate that he aims to show that every bone in human body is united to one another, which forms an organizing structure. I will conclude that these visual principles were used by Chelselden to achieve perfection by conveying right proportions and the correct number of scales of human body since his observations was laden with Newtonian paradigm. Finally, I will compare this usage to that of Ibn Sina’s, to disclose the paradigm-ladenness of scientific observations. (shrink)

It is necessary to take into account the data of science in the theoretical debates conducted by scientists contributing ontological theories in order to develop new approaches to theological issues in Islamic thought. Even, Kalam scholars with the duty of defending and basing the principles of Islam in the classical sense have established a theological understanding intertwined with science in understanding both existence philosophically and the Script theologically. With its discoveries and theories in the last century, it can be argued (...) that modern science has made a serious progress compared to the past. Maintaining its own methodology and paradigm, every scientific discipline has the opportunity to benefit from the methods and data of other disciplines. Consequently, it is possible to assert that Kalam can enjoy the same opportunity too, as long as staying in its own problem area. According to modern science, the motion system is the unity of structures that enable living things to move. Moreover, Bones and joints, which are the structures of the skeletal system, are passive elements of the movement system. Muscles, on the other hand, are the active elements of the movement system and provide the movement of the body by affecting the bones and joints. Muscle tissue shapes the body by adhering to the bones, besides enabling movement activity to occur. One of the most important systems that provide movement is the nervous system. Because for a person to have movement, the muscles must contract, and the muscles must be stimulated for the contraction of the muscles. The system that enables this contraction to occur is the nervous system. Energy is also required for contraction to occur in the human body. Muscles create energy for movement by first providing their energy from the ATP molecule present in the muscle cells. Considering the movement theories of classical theology scholars, it is seen that they shaped the occurrence of human actions through the concept of potency. While the scholars classify power as spiritual/mental and physical strength in terms of its structure, they have characterized it as accident in terms of its nature. In this context, we can say that the equivalent of the power, which is regarded as necessary for the formation of human acts by the theologians, is the movement system in today's science. The spirit/mental that scholars regard as a structure of power for the occurrence of human action can be regarded as the electrical activity that activates muscles when considered within the framework of the movement system of today's science. It is seen that Kalam scholars emphasize physical competence in their definitions of power as well. At this point, Ash'arians defined the power as the soundness of organs, Mu’tazila expressed it as the presence of organs and their being away from disasters, and the Mâturîdîs stated it as the organs being healthy. With these definitions, Kalam scholars mean that a person should also be physically competent to make a movement. The structures scientifically accepted as biological and physical competence in the movement system are the skeletal system, muscles and nervous system. Therefore, we can say that the strength of the physical fitness/well-being emphasized in the definition of power by theologians corresponds scientifically to the skeletal system, muscles and nervous system. One of the issues that Kalam scholars discuss about power is the issue of the accident of power. The reason why they describe power as an accident is to emphasize its impermanence and to show that it was created by Allah. So, in modern science, electrical activity must occur in the brain in order for human organs to move. The occurrence of this electrical activity is independent of the human being. The fact that electrical activity occurs independently from human beings shows that it conforms to Kalam scholars’ definition of the accident. As a result, we can say that the theory of power created by scholars for human movement has a counterpart in the movement system put forward by today's science. (shrink)

Although emotion is closely associated with motivation, and interacts with perception, cognition, and action, many conceptualizations still treat emotion as separate from these domains. Here, a comparative/evolutionary anatomy framework is presented to motivate the idea that long-range, distributed circuits involving the midbrain, thalamus, and forebrain are central to emotional processing. It is proposed that emotion can be understood in terms of large-scale network interactions spanning the neuroaxis that form “functionally integrated systems.” At the broadest level, the argument is (...) made that we need to move beyond a Newtonian view of causation to one involving complex systems where bidirectional influences and nonlinearities abound. Therefore, understanding interactions between subsystems and signal integration becomes central to unraveling the organization of the emotional brain. (shrink)

A growing literature is taking an institutionalist and governance perspective on how algorithms shape society based on unprecedented capacities for managing social complexity. Algorithmic governance altogether emerges as a novel and distinctive kind of societal steering. It appears to transcend established categories and modes of governance—and thus seems to call for new ways of thinking about how social relations can be regulated and ordered. However, as this paper argues, despite its novel way of realizing outcomes of collective steering and coordination, (...) it can nevertheless be grasped with an old and fundamental figure in political philosophy: that of Thomas Hobbes’ Leviathan. Comparing algorithmic governance with this figure serves to highlight their similarities as socio-political arrangements, and specifically to clarify how algorithmic governance parallels the apolitical traits of the Leviathan—it eliminates the political as it requires compliance and forgoing contestation to best fulfill its role and to produce satisfying outcomes. (shrink)

Many decades ago Patrick Suppes argued rather convincingly that theoretical hypotheses are not confronted with the direct, raw results of an experiment, rather, they are typically compared with models of data. What exactly is a data model however? And how do the interactions of particles at the subatomic scale give rise to the huge volumes of data that are then moulded into a polished data model? The aim of this paper is to answer these questions by presenting a detailed case (...) study of the construction of data models at the LHCb for testing Lepton Flavour Universality in rare decays of B-mesons. The close examination of the scientific practice at the LHCb leads to the following four main conclusions: raw data in their pure form are practically useless for the comparison of experimental results with theory, and processed data are in some cases epistemically more reliable, real and simulated data are involved in the co-production of the final data model and cannot be easily distinguished, theory-ladenness emerges at three different levels depending on the scope and the purpose for which background theory guides the overall experimental process and the overall process of acquiring and analysing data in high energy physics is too complicated to be fully captured by a generic methodological description of the experimental practice. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Dimensions of the Sacred: An Anatomy of the World's BeliefsRobert Cummings NevilleDimensions of the Sacred: An Anatomy of the World's Beliefs. By Ninian Smart. Berkeley: University of California Press. Pp. 359. $17.95.After decades of nervous retreat from the projects of understanding religions in comparative perspective and religion itself as a complex artifact of human culture, these projects are showing new signs of life, of which (...) "the late" Ninian Smart's Dimensions of the Sacred: An Anatomy of the World's Beliefs is one of the most important so far. Good reasons have justified the retreat, however, at least a little. One was embarrassment at the quickness with which Christianity was taken to be the paradigm of religion according to which the others were analyzed, an embarrassment that applies to eighteenth-century studies and some twentieth-century philosophy of religion more than to recent studies and is hence sometimes over-estimated. Another embarrassment was the kind of analysis associated with Hegel, in which important differences among religions were noted but Christianity very quickly turns out to be the best; this continues to be an issue of concern whenever the analysis takes place from the standpoint of a religious culture. A subtler embarrassment comes from a political analysis that points out that the colonial dominance of Western culture marginalizes religions that should be given greater importance, or marginalizes certain aspects of religion such as its popular expressions. [End Page 420]Another caution, if not embarrassment, comes from those who insist that religions are so singular that any attempt to compare them or lift up certain categories that might fit into an explanatory theory necessarily biases their representation; not that the categories compared are not present, but that these categories are not the important ones for the religion at hand. Moreover, hosts of new critical disciplines have arisen that look for precisely the things that biases exclude from view, starting with women and moving through marginalized persons and religious expressions; these disciplines say that the traditions of comparison and explanation have done a bad job. A final caution that has urged retreat is that most comparative and explanatory projects are reductive in the sense of taking one discipline, say theology, anthropology, myth studies, or whatever, to be the focus of comparison.There are ways now of controlling for all of these destructive biases in the comparative and explanatory enterprises, and Ninian Smart's book is an admirable introduction to them all.Of course the greatest strength of Smart's book is Smart himself. He has lived through all of the criticisms of these projects and has amassed such enormous erudition that his arguments carry powerful inertia against all these objections. He says, rightly, that both comparison and explanation still have far to go and that he is presenting hypotheses here that move these projects forward. He also would admit that his treatment of any religious idea, figure, or movement can always be criticized by specialists as not sufficiently detailed or nuanced. That goes with the territory of any comparison or explanation. Nevertheless, he can argue, and this reviewer agrees, that his characterizations of religions and comparisons generally articulate what is important, and that exceptions can be registered within his approach; he can also say that his explanations are hypotheses that might be improved upon but that cannot be rejected as having no explanatory force.As readers of Smart's earlier work might suspect, the explanatory analysis here is based on his idea of the dimensions of religion, explained in The Religious Experience (1969) and The World's Religions (1989). These dimensions, each of which commands a chapter of this book, are: the ritual or practical, the doctrinal or philosophical, the mythic or narrative, the experiential or emotional, the ethical or legal, the organizational or social, and the material or artistic; the book adds a chapter on the political dimension. Each dimension is characterized by two terms that between them brace a spectrum of elements. Among themselves the dimensions are sufficiently different in clear ways as to push attention to aspects of religion likely to be obscured from within any dimension, yet within themselves they are... (shrink)

The neural correlates of two hypothesized emotional processing modes, i.e., schematic and propositional modes, were investigated with positron emission tomography. Nineteen subjects performed an emotional mental imagery task while mentally repeating sentences linked to the meaning of the imagery script. In the schematic conditions, participants repeated metaphoric sentences, whereas in the propositional conditions, the sentences were explicit questions about specific emotional appraisals of the imagery scenario. Five types of emotional scripts were proposed to the subjects (happiness, anger, affection, sadness, and (...) a neutral scenario). The results supported the hypothesized distinction between schematic and propositional emotional processing modes. Specifically, schematic mode was associated with increased activity in the ventromedial prefrontal cortex whereas propositional mode was associated with activation of the anterolateral prefrontal cortex. In addition, interaction analyses showed that schematic versus propositional processing of happiness (compared with the neutral scenario) was associated with increased activity in the ventral striatum whereas “schematic anger” was tentatively associated with activation of the ventral pallidum. © 2003 Elsevier Science (USA). All rights reserved. (shrink)

This paper focuses on the contributions to natural history, particularly in methods of plant classification of the Portuguese botanist, man of letters, diplomat, and Freemason Abbé José Correia da Serra (1751-1823), placing them in their national and international political and social contexts. Correia da Serra adopted the natural method of classification championed by the Frenchman Antoine-Laurent de Jussieu, and introduced refinements of his own that owe much to parallel developments in zoology. He endorsed the view that the classification of plants (...) should be based on the establishment of affinities rather than of differences. The emphasis on affinities went hand in hand with the development of the concept of symmetry. This idea was introduced by Correia da Serra in systematics and was adopted and further developed by his friend, Augustin-Pyramus de Candolle. Correia da Serra also argued that Cryptogamia reproduce sexually, advocated extension of methods of comparative anatomy from zoology to botany, and applied them to the study of fruits. Correia da Serra was one among many of the estrangeirados, Portuguese "Europeanized" intellectuals who traveled extensively abroad in most cases to escape political or religious persecution at home. The estrangeirados were important contributors to 18th and 19th century European thinking. Most of the estrangeirados were pivotal in the introduction, dissemination and propagation of the new sciences in Portugal, but unlike most of his fellow estrangeirados, Correia da Serra was also an innovative man of science in his own right. (shrink)

Medicine and astronomy were both scientific disciplines to which visual demonstration proved helpful, were taught in the universities, and were deeply influenced by humanism and by the development of print culture, but they did not use printed images in the same way. Thus, all the aspects of astronomical activity benefited from the accompaniment of printed images, whereas, even for anatomy, illustration does not seem to have been seen as a necessity in Renaissance medical books. To explore such a difference, (...) the chronology of the development of illustration in both fields (from the first illustrated incunabula to the mid-sixteenth century) is compared, and some explanations (economical, epistemological, cultural) are proposed and questioned. -/- . (shrink)

At the end of the nineteenth century, Ludwig Edinger completed the first comparative survey of the microscopic anatomy of vertebrate brains. He is regarded as the founder of the field of comparative neuroanatomy. Modern commentators have misunderstood him to have espoused an anti-Darwinian linear view of brain evolution, harkening to the metaphysics of the scala naturae. This understanding arises, in part, from an increasingly contested view of nineteenth-century morphology in Germany. Edinger did espouse a progressionist, though not (...) strictly linear, view of forebrain evolution, but his work also provided carefully documented evidence that brain stem structures vary in complexity independently from one another and across species in a manner that is not compatible with linear progress. This led Edinger to reject progressionism for all brain structures other than the forebrain roof, based on reasoning not too dissimilar from those his successors used to dismiss it for the forebrain roof. (shrink)

Where is consciousness? Neurobiological theories of consciousness look primarily to synaptic firing and “spike codes” as the physical substrate of consciousness, although the specific mechanisms of consciousness remain unknown. Synaptic firing results from electrochemical processes in neuron axons and dendrites. All neurons also produce electromagnetic (EM) fields due to various mechanisms, including the electric potential created by transmembrane ion flows, known as “local field potentials,” but there are also more meso-scale and macro-scale EM fields present in the brain. The functional (...) role of these EM fields has long been a source of debate. We suggest that these fields, in both their local and global forms, may be the primary seat of consciousness, working as a gestalt with synaptic firing and other aspects of neuroanatomy to produce the marvelous complexity of minds. We call this assertion the “electromagnetic field hypothesis.” The neuroanatomy of the brain produces the local and global EM fields but these fields are not identical with the anatomy of the brain. These fields are produced by, but not identical with, the brain, in the same manner that twigs and leaves are produced by a tree’s branches and trunk but are not the same as the branches and trunk. As such, the EM fields represent the more granular, both spatially and temporally, aspects of the brain’s structure and functioning than the neuroanatomy of the brain. The brain’s various EM fields seem to be more sensitive to small changes than the neuroanatomy of the brain. We discuss issues with the spike code approach as well as the various lines of evidence supporting our argument that the brain’s EM fields may be the primary seat of consciousness. This evidence (which occupies most of the paper) suggests that oscillating neural EM fields may make firing in neural circuits oscillate, and these oscillating circuits. may help unify and guide conscious cognition. (shrink)

Machine generated contents note: General editor's preface; Editorial notes and references; Introduction; Notes on text and translation; Chronology; Bibliography; Part I. On the Fourfold Root of the Principle of Sufficient Reason: 1. Introduction; 2. Survey of what is most important in previous teachings about the principle of sufficient reason; 3. Inadequacy of previous accounts and sketch of a new one; 4. On the first class of objects for the subject and the form of the principle of sufficient reason governing in (...) it; 5. On the second class of objects for the subject and the form of the principle of sufficient reason governing in it; 6. On the third class of objects for the subject and the form of the principle of sufficient reason governing in it; 7. On the fourth class of objects for the subject and the form of the principle of sufficient reason governing in it; 8. General remarks and results; Variants in different editions; Collation of the two editions; Part II. On Vision and Colours: 9. On vision; 10. On colours; Variants in different editions; Part III. On Will in Nature: 11. Introduction; 12. Physiology and pathology; 13. Comparative anatomy; 14. Plant physiology; 15. Physical astronomy; 16. Linguistics; 17. Animal magnetism and magic; 18. Sinology; Reference to ethics; Conclusion; Variants in different editions; Glossary of names; Index. (shrink)

The concept of similarity plays a crucial role in biology, especially in natural history. Despite its apparent familiarity it has been subject again and again to reinterpretations — it may even be stated that the main streams of theoretical thinking in the life sciences are reflected and condensed in its ever changing meaning. The changing content of the concept is analyzed from Linnaean systematics through classical morphology and comparative anatomy to Darwinian evolutionary thinking. It appears that the meaning (...) of similarity is inseparable from the function of the concept in theory, viz. its operational determination. In addition a remarkable correspondence has to be recognized between the notion of similarity and the conceptualization of an organism as the basic unit of life. (shrink)

One foundational question in contemporarybiology is how to `rejoin evolution anddevelopment. The emerging research program(evolutionary developmental biology or`evo-devo) requires a meshing of disciplines,concepts, and explanations that have beendeveloped largely in independence over the pastcentury. In the attempt to comprehend thepresent separation between evolution anddevelopment much attention has been paid to thesplit between genetics and embryology in theearly part of the 20th century with itscodification in the exclusion of embryologyfrom the Modern Synthesis. This encourages acharacterization of evolutionary developmentalbiology as the marriage (...) of evolutionary theoryand embryology via developmental genetics. Butthere remains a largely untold story about thesignificance of morphology and comparativeanatomy (also minimized in the ModernSynthesis). Functional and evolutionarymorphology are critical for understanding thedevelopment of a concept central toevolutionary developmental biology,evolutionary innovation. Highlighting thediscipline of morphology and the concepts ofinnovation and novelty provides an alternativeway of conceptualizing the `evo and the `devoto be synthesized. (shrink)

Se presentan y comparan entre sí procesos o secuencias evolutivas que se reconocen en diferentes disciplinas fácticas. Un modelo generalizado intenta reunir y focalizar el estudio comparado entre el desarrollo genético , la embriogénesis y la psicogénesis . Se buscan caracteres adecuados que permitan reconocer, por medio de sus diferentes estados, las interdependencias entre los diferentes niveles de organización. La sucesión de los estados que se correlacionan debe respetar una dirección obligada para permitir el normal desenvolvimiento de los procesos teleonómicos (...) respectivos. El modelo compartido entre procesos geológicos y secuencias paleobiogeográficas es analizado para evaluar posibilidades y limitaciones en la formulación de conexiones y predicciones relacionadas con la evolución que se da en cada campo. Se redefine la noción de homología procedente del campo de la biologia. Se analiza su posible aplicación en el desarrollo de la hipótesis que cree reconocer en el “mundo” de la Biología un “puente” entre los “mundos” del fisicalismo y aquellos de la conciencia y los fenómenos socioculturales.This paper deals with interrelations among different fields of the factual disciplines. A generalized model of teleonomic processes, observed at different levels, is proposed. It includes genetic development in comparison with embryogenesis and psycogenesis . The search for features in common between three levels, including their respective states of development, is emphasized. The recognition of these characters and their states allows for comparison between the three levels and, particularly the recognition of a common process involved. These data are relevant when deciding whether the similarities between the three levels represent convergences or if they are instead cases of unavoidable homology. In addition, cases from the fossil record exhibiting interdependencies between the respective patterns of evolution and geographical change, are considered. These cases allow for the anticipation of as well as limited predictions about the course of the evolutionary change. An amendment to the notion of homology, taken from comparative anatomy, is proposed. This revised definition of homology attempts to broaden the meaning of the term in order to apply it in the search of links between different levels of knowledge organization. In the present contribution the role of Bbiology as a bridge between the physical and the socio-cultural realms is emphasized. (shrink)