The quality and quantity of training data are crucial to the performance of a deep-learning-based brain-computer interface system. However, it is not practical to record EEG data over several long calibration sessions. A promising time- and cost-efficient solution is artificial data generation or data augmentation. Here, we proposed a DA method for the motor imagery EEG signal called brain-area-recombination. For the BAR, each sample was first separated into two ones by left/right brain channels, and the artificial samples were generated by (...) recombining the half-samples. We then designed two schemas corresponding to the single- and multi-subject scenarios. Extensive experiments using the classifier of EEGnet were conducted on two public datasets under various training set sizes. In both schemas, the BAR method can make the EEGnet have a better performance of classification. To make a comparative investigation, we selected two common DA methods, and the BAR method beat them. Further, using the proposed BAR for augmentation, EEGnet achieved up to 8.3% improvement than a typical decoding algorithm CSP-SVM, note that both the models were trained on the augmented dataset. This study shows that BAR usage can significantly improve the classification ability of deep learning to MI-EEG signals. To a certain extent, it may promote the development of deep learning technology in the field of BCI. (shrink)

Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia (MIA) are still largely unknown. We recruited FM patients ( n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 min without external noise from fMRI image acquisition. Resting state fMRI was then acquired before and after the music and control conditions. A significant increase in the amplitude of low frequency fluctuations of the BOLD (...) signal was evident in the left angular gyrus (lAnG) after listening to music, which in turn, correlated to the analgesia reports. The post-hoc seed-based functional connectivity analysis of the lAnG showed found higher connectivity after listening to music with right dorsolateral prefrontal cortex (rdlPFC), the left caudate (lCau), and decreased connectivity with right anterior cingulate cortex (rACC), right supplementary motor area (rSMA), precuneus and right precentral gyrus (rPreG). Pain intensity (PI) analgesia was correlated ( r = 0.61) to the connectivity of the lAnG with the rPreG. Our results show that MIA in FM is related to top-down regulation of the pain modulatory network by the default mode network (DMN). (shrink)

Ben shu yi Wang Yangming di zi Zou Dongkuo wei yan jiu dui xiang, zhuo zhong tan tao qi si xiang jie gou he nei han, bing jiang dui qi ge ti zhe xue si xiang de yan jiu na ru dao zheng ge Yangming xue fen hua, yan bian de li shi jin cheng zhong lai que ding qi ge ti de si xiang shi ding wei, jie yi kao cha qi ge ti de si xiang te se (...) he zheng ge Yangming xue zai zhong wan Ming de fa zhan te dian. (shrink)

In this paper, we mainly investigate the existence of states based on the Glivenko theorem in bounded semihoops, which are building blocks for the algebraic semantics for relevant fuzzy logics. First, we extend algebraic formulations of the Glivenko theorem to bounded semihoops and give some characterizations of Glivenko semihoops and regular semihoops. The category of regular semihoops is a reflective subcategory of the category of Glivenko semihoops. Moreover, by means of the negative translation term, we characterize the Glivenko variety. Then (...) we show that the regular semihoop of regular elements of a free algebra in the variety of Glivenko semihoops is free in the corresponding variety of regular semihoops. Similar results are derived for the semihoop of dense elements of free Glivenko semihoops. Finally, we give a purely algebraic method to check the existence of states on Glivenko semihoops. In particular, we prove that a bounded semihoop has Bosbach states if and only if it has a divisible filter, and a bounded semihoop has Riečan states if and only if it has a semi-divisible filter. (shrink)

Authoritarian leadership is of great significance to eastern countries, including China. Meanwhile, unethical employee behavior also exists in all types of social organizations. The relationship between authoritarian leadership and unethical employee behavior is worth studying. Senior leaders often do not have a direct influence on employees except for through their immediate supervisors. The leadership style of senior leaders also influences the leadership style of their subordinates. This paper studies how authoritarian manager leadership trickles down to unethical employee behavior through authoritarian (...) supervisor leadership and discusses the moderating effect of leader member exchange and an ethical climate. Through a questionnaire survey of 406 pairs of leaders, supervisors, and employees, the research results of the multilevel model show that authoritarian supervisor leadership is positively related to unethical employee behavior, authoritarian supervisor leadership mediates the relationship between authoritarian manager leadership and unethical employee behavior, LMX positively moderates the relationship between authoritarian manager leadership and authoritarian supervisor leadership and moderates the mediating effect of authoritarian supervisor leadership, and, that an ethical climate negatively moderates the relationship between authoritarian supervisor leadership and unethical employee behavior and moderates the mediating effect of authoritarian supervisor leadership. (shrink)

While an increasing number of organizations have introduced artificial intelligence as an important facilitating tool for learning online, the application of artificial intelligence in e-learning has become a hot topic for research in recent years. Over the past few decades, the importance of online learning has also been a concern in many fields, such as technological education, STEAM, AR/VR apps, online learning, amongst others. To effectively explore research trends in this area, the current state of online learning should be understood. (...) Systematic bibliometric analysis can address this problem by providing information on publishing trends and their relevance in various topics. In this study, the literary application of artificial intelligence combined with online learning from 2010 to 2021 was analyzed. In total, 64 articles were collected to analyze the most productive countries, universities, authors, journals and publications in the field of artificial intelligence combined with online learning using VOSviewer through WOS data collection. In addition, the mapping of co-citation and co-occurrence was explored by analyzing a knowledge map. The main objective of this study is to provide an overview of the trends and pathways in artificial intelligence and online learning to help researchers understand global trends and future research directions. (shrink)

Resumo: O pós-modernismo ocidental é uma tendência cultural de pensamento que surgiu nas décadas de 1960 e 1970. Sua influência envolve muitos campos, como arte, literatura, filosofia e estética, o que indica que uma grande mudança ocorreu em toda a sociedade ocidental e também tem um impacto profundo na cultura e na arte contemporâneas. Ao analisar a influência de longo alcance do pós-modernismo, na música e na filosofia, este artigo fornece estratégias de desenvolvimento e sugestões para a música e a (...) filosofia, sob o pano de fundo do pós-modernismo. Este texto estudou os efeitos positivos e negativos do pós-modernismo na filosofia e na música, sob dois aspectos: música e filosofia. A influência positiva do pós-modernismo na filosofia e na música manifesta-se na defesa da igualdade, da harmonia entre o homem e a natureza, da inovação e do espírito crítico. É claro que a tendência de pensamento do pós-modernismo também tem alguns efeitos negativos, os quais devem ser vistos dialeticamente, em seu impacto sobre a música e a filosofia. Com a premissa de incentivar a inovação, respeitar a liberdade e a diferença, deve-se estabelecer uma autoconfiança de valor, de modo a promover o desenvolvimento da filosofia e da música. O pós-modernismo é uma forma cultural do período posterior do capitalismo. No campo da música, é necessário não apenas aderir à rebeldia e à abertura trazidas pelo pós-modernismo, mas também dar importância ao valor artístico das obras musicais para evitar a produção e a proliferação de obras musicais vulgarizadas. A influência do pós-modernismo na música e na filosofia, que estudamos neste artigo, tem um significado prático importante. (shrink)

ObjectiveThe study aimed to enhance the learning motivation of college physical education students and improve their learning outcomes. Based on the perspective of the self-determination theory, this study explores the influence of “Small Private Online Course + flipped classroom” teaching on the learning motivation of students majoring in physical education and profoundly analyzes the influencing factors and promotion paths of learning motivation using this model.Materials and methodsA total of four classes of physical education majors in a university were selected and (...) randomly divided into an experimental group and a control group. The experimental group received “SPOC + flipped classroom” teaching, the control group received traditional teaching. Before and after the 16-week intervention, learning motivation, teacher support perception, basic psychological need satisfaction, and academic emotions of the 64 students were measured, and the data were analyzed by repeated-measures analysis of variance and partial least square regression.Results The instructional intervention reduced non-regulation, external regulation, and introjected regulation, while increased identified regulation, intrinsic regulation, and self-determination levels in the students. The levels of non-regulation, external regulation, identified regulation, and self-determination were also significantly different from those of the control group. After the intervention, the scores of support for autonomy, support for competence, support for relatedness, and need for relatedness in the experimental group were significantly higher than those in the control group. Support for autonomy, support for competence, support for relatedness, need for competence and need for relatedness positively predicted the self-determination level, and intrinsic regulation and identified regulation negatively predicted non-regulation, external regulation, and introjected regulation.Conclusion“SPOC + flipped classroom” teaching has a positive impact on students’ learning motivation of basketball skills and promotes students’ motivation autonomy. The improvement of support for autonomy, support for competence, support for relatedness, need for competence, and need for relatedness may be related to the improvement of learning motivation of college students majoring in Physical Education. “SPOC + flipped classroom” teaching enables students to obtain more demand satisfaction by giving them more demand support, while demand support and demand satisfaction can promote the internalization of learning motivation so that students can maintain high autonomy motivation. (shrink)

To explore whether the generation of new protein folds could be linked to metallic cofactor recruitment, we identified the oldest examples of folds for manganese, iron, zinc, and copper proteins by analyzing their fold‐domain mapping patterns. We discovered that the generation of these folds was tightly coupled to corresponding metals. We found that the emerging order for these folds, i.e., manganese and iron protein folds appeared earlier than zinc and copper counterparts, coincides with the putative bioavailability of the corresponding metals (...) in the ancient anoxic ocean. Therefore, we conclude that metallic cofactors, like organic cofactors, play an evolutionary role in the formation of new protein folds. This link could be explained by the emergence of protein structures with novel folds that could fulfill the new protein functions introduced by the metallic cofactors. These findings not only have important implications for understanding the evolutionary mechanisms of protein architectures, but also provide a further interpretation for the evolutionary story of superoxide dismutases. (shrink)

The fifth base in human DNA, 5‐methylcytosine, is inherently mutagenic. This has led to marked changes in the distribution of the CpG methyl acceptor site and an 80% depletion in its frequency of occurrence in vertebrate DNA. The coding regions of many genes contain CpGs which are methylated in sperm and serve as hot spots for mutation in human genetic diseases. Fully 30–40% of all human germline point mutations are thought to be methylation induced even though the CpG dinucleotide is (...) under‐represented and efficient cellular repair systems exist. Importantly, tumor suppressor genes such as p53 also contain methylated CpGs and these serve as hot spots for mutations in some, but not all, human cancers. Comparison of the spectrum of mutations present in this gene in different human cancers allows for predictions to be made on the molecular mechanisms of tumorigenesis. (shrink)

This study determines gender differences in the generation logic for green purchasing intention within the framework of bounded morality and bounded self-interest and determines the causes of the attitude–behavior gap from a new perspective. Empirical analysis of 977 sample data points is used to test the influencing mechanism of gender heterogeneity on green purchasing intention through altruistic values and egoistic values. Meanwhile, the moderated mediation effects are also analyzed. The results show that gender heterogeneity negatively affects ALVs and positively affects (...) EGVs for women as the reference group. The mediation effect of ALVs and EGVs is significant, and there are significant gender differences in the formation of values and green purchasing intention. As expected, women demonstrate higher levels of proenvironmental intention than men. Media exposure significantly moderates the mediation models. It negatively moderates the mediation effect of ALVs and positively moderates the mediation effect of EGVs. The results reveal the complex formation mechanism for green purchasing intention. It can conclude that the gender differences in terms of green purchasing, the different guiding roles of dual values, and the moderated mechanism of ME are key elements in accurate guidance of green consumption and the effective modification of the attitude–behavior gap. (shrink)

Personality disorders are usually treated with face-to-face sessions and/or digital mental health services. Among many schools of therapies, schema therapy stands out because rather than simply targeting the symptoms of PD, it cordially targets the cause of PD and heals the early maladaptive schema, thus is exceptionally good at soothing emotional disturbances before enacting cognitive restructuring, resulting in long-term efficacy. However, according to Piaget’s genetic epistemology, the unmet needs lie in the fact that the schemata that determine the adaptive behavior (...) can only be formed in the interaction with the real world that the patient is living in and reconsolidated by the feedback from the object world upon the patient’s newly-formed behavior. Therefore, in order to reshape the patient’s schema modes to support adaptive behavior and regain emotional regulation capabilities of the healthy adult, one may have to reconstruct the object world surrounding the patient. Metaverse, the bestowed successor to the Internet with the cardinal feature of “the sense of full presence,” can become a powerful tool to reconstruct a new object world for the patient with the prescription of a psychotherapist, so as to transform the treatment techniques in schema therapy into the natural autobiographical experiences of patients in the new object world, thus gradually reshape the patient’s schema modes that can ultimately result in an adaptive, and more inclusive, interaction with the real world. This work describes the underlying theory, the mechanism, the process, and ethical considerations of such promising technology for the not-too-far future. (shrink)

Closed-loop transcutaneous auricular vagal nerve stimulation was officially proposed in 2020. This work firstly reviewed two existing CL-taVNS forms: motor-activated auricular vagus nerve stimulation and respiratory-gated auricular vagal afferent nerve stimulation, and then proposed three future CL-taVNS systems: electroencephalography -gated CL-taVNS, electrocardiography -gated CL-taVNS, and subcutaneous humoral signals -gated CL-taVNS. We also highlighted the mechanisms, targets, technical issues, and patterns of CL-taVNS. By reviewing, proposing, and highlighting, this work might draw a preliminary blueprint for the development of CL-taVNS.

This essay is an attempt to sketch out two contrasting notions of freedom in the Zhuangzi and the Xunzi . I argue that to understand the classical Chinese formulations of freedom we should look at the concept of hua 化 (transformation or to transform). It is a kind of freedom that highlights the moral and/or spiritual transformation of the self and its entailments on the connection between the self and various domains of relationality. The Zhuangzian hua is the transformation of (...) the self in such a way that the self becomes supremely attuned to the complexity of the world and can thus navigate various domains of relationality with extraordinary grace, ease, and efficacy. The Xunzian hua is the transformation of the self so that the self can extend its relationality to include the entire world and transform it from a raw and uncouth world to a civilized one through ritual practices. (shrink)

If we do not shrink from making rough generalizations and adopt a broad, conventional approach, then what we call modernity refers to the process whereby a state of heterogeneity progresses toward homogeneity in time, space, human collectives, social order, and other areas. In his book The Cheese and the Worms, Carlo Ginzburg discusses a late-16th century incident of heterodoxy that cannot be classified into previously existing standard categories. As new knowledge was disseminated thanks to the invention of the Gutenberg printing (...) press, old and new knowledge came into conflict in the mind of a heterodox figure by the name of Menocchio. He attacked the church, saying that it was more important to love one’s neighbor than to love God. Through these small, humble manifestations of change, Ginzburg was able to reveal the juncture when European modern knowledge first emerged from a muddled, undifferentiated state into one of clarity, whereby over the course of about a century of fermentation, its contours eventually became clearly evident around the year 1800. This process has been termed by the pioneer of conceptual history Otto Brunner as the “threshold era”, and by Reinhart Koselleck as the beginning of the “saddle era”. (shrink)

The relationship between philosophy and science in contemporary times is closer than ever. From the methodology perspective, scientific and philosophical research has a clear sequential relationship. It is highlighted in the following aspects: 1. the methodology of scientific research, including theoretical assumptions and data modeling, parallels with apparent similarities in conceptual analysis and logical deduction in philosophy;2. consistency of analytical argumentation methods in scientific research and philosophical research;3. naturalism is currently a research approach that both scientific and philosophical research adopt. (...) There has been a significant dispute over the relationship between philosophy and science among contemporary philosophers. This dispute focuses on the impact of scientific development on philosophy research. Nowadays, no one would deny the existence of this impact, but there is no consensus on the impact's nature, scope, and role. Wittgenstein's conception of certainty can provide valuable insights to understand the relationship between philosophy and science. In addition, we conclude the pragmatic turn in cognitive science because we misinterpret the cognitive scientists' emphasis on action as a practical claim and interpret the cognitive scientists' views with pragmatism. The theoretical analysis and research suggestions philosophers provide are becoming essential focuses in contemporary artificial intelligence research, including the interpretability of computer technology, the ethical norms of artificial intelligence technology, and the possible conception of human beings in the future. The interdisciplinary study of science and philosophy will achieve more significant development. In sum, understanding the nature of philosophy can be given a new explanation from a future perspective. The future outlook here refers to the starting point from possible world scenarios that can be conceived and traced back to all the facts happening in the present world, thereby giving an appropriate explanation to the real world. (shrink)

DNA replication stress threatens ordinary DNA synthesis. The evolutionarily conserved DNA replication stress response pathway involves sensor kinase Mec1/ATR, adaptor protein Mrc1/Claspin, and effector kinase Rad53/Chk1, which spurs a host of changes to stabilize replication forks and maintain genome integrity. DNA replication forks consist of largely distinct sets of proteins at leading and lagging strands that function autonomously in DNA synthesis in vitro. In this article, we discuss eSPAN and BrdU‐IP‐ssSeq, strand‐specific sequencing technologies that permit analysis of protein localization and (...) DNA synthesis at individual strands in budding yeast. Using these approaches, we show that under replication stress Rad53 stalls DNA synthesis on both leading and lagging strands. On lagging strands, it stimulates PCNA unloading, and on leading strands, it attenuates the replication function of Mrc1‐Tof1. We propose that in doing so, Rad53 couples leading and lagging strand DNA synthesis during replication stress, thereby preventing the emergence of harmful ssDNA. (shrink)

本书以专题的形式对哲学的一些基本理论、基本知识作了既有一定理论深度又有比较通俗易懂的阐述.

The relationship between philosophy and science in contemporary times is closer than ever. From the methodology perspective, scientific and philosophical research has a clear sequential relationship. It is highlighted in the following aspects: 1. the methodology of scientific research, including theoretical assumptions and data modeling, parallels with apparent similarities in conceptual analysis and logical deduction in philosophy;2. consistency of analytical argumentation methods in scientific research and philosophical research;3. naturalism is currently a research approach that both scientific and philosophical research adopt. (...) There has been a significant dispute over the relationship between philosophy and science among contemporary philosophers. This dispute focuses on the impact of scientific development on philosophy research. Nowadays, no one would deny the existence of this impact, but there is no consensus on the impact's nature, scope, and role. Wittgenstein's conception of certainty can provide valuable insights to understand the relationship between philosophy and science. In addition, we conclude the pragmatic turn in cognitive science because we misinterpret the cognitive scientists' emphasis on action as a practical claim and interpret the cognitive scientists' views with pragmatism. The theoretical analysis and research suggestions philosophers provide are becoming essential focuses in contemporary artificial intelligence research, including the interpretability of computer technology, the ethical norms of artificial intelligence technology, and the possible conception of human beings in the future. The interdisciplinary study of science and philosophy will achieve more significant development. In sum, understanding the nature of philosophy can be given a new explanation from a future perspective. The future outlook here refers to the starting point from possible world scenarios that can be conceived and traced back to all the facts happening in the present world, thereby giving an appropriate explanation to the real world. (shrink)

Xiong Shili / Li Shuangqing zhu -- Zhang Junmai / Jiang Yongzhen zhu -- Jiang Zhongzheng / Wu Jiping zhu.

This paper discusses some paradoxical propositions in Chinese tradition, especially the School of Names. It not only explains what Chinese philosophers mean by these propositions and why there are such paradoxes in Chinese philosophy, but also makes an attempt to formulate these paradoxical propositions in the language of symbolic logic. Meanwhile, the paper makes a comparison between Chinese views about contradiction and Aristotle?s law ot non?contradiction and explores the relation between them. It comes to the conclusion that once the difference (...) between Chinese concept of contraries and Aristotle?s is made clear, inconsistency between Chinese paradoxial propositions and Aristotle?s. law of non-contradiction disappears. (shrink)

The study aims to help characterize the sort of structures about which people can acquire unconscious knowledge. It is already well established that people can implicitly learn n-grams and also repetition patterns. We explore the acquisition of unconscious structural knowledge of symmetry. Chinese Tang poetry uses a specific sort of mirror symmetry, an inversion rule with respect to the tones of characters in successive lines of verse. We show, using artificial poetry to control both n-gram structure and repetition patterns, that (...) people can implicitly learn to discriminate inversions from non-inversions, presenting a challenge to existing models of implicit learning. (shrink)