This paper presents what the authors call the ‘divergence problem’ regarding choosing between different future possibilities. As is discussed in the first half, the central issue of the problem is the difficulty of temporally locating the ‘active cause’ on the modal divergent diagram. In the second half of this paper, we discuss the ‘second-person freedom’ which is, strictly, neither compatibilist negative freedom nor incompatibilist positive freedom. The divergence problem leads us to two hypothetical views (i.e. the view of single-line determination (...) and that of one-off chance), and these views bring humans closer to the afree side – i.e. outside of the contrast between being free and being unfree. The afree side is greatly different from the ordinary human side. This paper tries to secure the second-person freedom as a substitute for the ordinary human freedom while preventing the divergence problem from arising. (shrink)

Moral reasoning develops rapidly in early childhood. Recent evidence from cognitive neuroscience literature suggests that the development of moral reasoning is supported by an integration of cognitive and affective components. However, the role of culture in the development of moral reasoning in young children is under-investigated. Previous cross-cultural research suggests that culture shapes how people interpret other’s behaviors. In particular, people raised in independent cultures, such as the United States, tend to form impressions of others and attribute others’ behaviors to (...) their personal dispositions more quickly than people raised in interdependent cultures, such as Japan. In the present cross-cultural study, we examined parents’ discourse with children in Japan and the United States. Parents and their 3- to 4-year-old children were asked to view and discuss cartoon characters depicting prosocial and antisocial acts. Results indicated that in both cultures, parents discussed about moral actions of characters. Furthermore, United States parents were more likely to evaluate dispositional characteristics of characters based on their pro-social and anti-social acts, whereas Japanese parents were more likely to refer to emotion of the characters who got hurt. We discuss implications of cross-cultural differences and similarities in parental moral socialization and the development of moral reasoning in young children. (shrink)

Emotion modulates our time perception. So far, the relationship between emotion and time perception has been examined with visible emotional stimuli. The present study investigated whether invisible emotional stimuli affected time perception. Using continuous flash suppression, which is a kind of dynamic interocular masking, supra-threshold emotional pictures were masked or unmasked depending on whether the retinal position of continuous flashes on one eye was consistent with that of the pictures on the other eye. Observers were asked to reproduce the perceived (...) duration of a frame stimulus that was concurrently presented with a masked or unmasked emotional picture. As a result, negative emotional stimuli elongated the perceived duration of the frame stimulus in comparison with positive and neutral emotional stimuli, regardless of the visibility of emotional pictures. These results suggest that negative emotion unconsciously accelerates an internal clock, altering time perception. (shrink)

Freezing of gait is a common symptom in the late stages of Parkinson’s disease and related disorders. Videos are the gold standard method to conduct FOG scoring; however, the measurement accuracy of FOG scoring based on videos has not been formally assessed, despite its use in previous studies. This study aimed to calculate the measurement accuracy of video-based FOG scoring. Three evaluators scored the FOG based on 157 video data points collected from 21 patients using an annotation tool. One evaluator (...) measured the intra-rater reliability of the retest. The total duration of observed FOG, percentage of the time spent with FOG during the walking task, and FOG phenotypes were evaluated. Intraclass correlation coefficients were used to determine the intra- and inter-rater reliabilities. The duration of FOG and %FOG showed good measurement accuracy for both intra-rater and inter-rater reliabilities. However, the FOG phenotypes showed poor measurement accuracy in inter-rater reliability. These results indicate that the temporal characteristics of FOG can be scored with a high degree of measurement accuracy, even with different evaluators; conversely, the FOG phenotypes need to be scored by several evaluators. (shrink)

Research in the U.S. developed and validated the State Self-Compassion Scale, which measures self-compassionate reactions toward a specific negative event. The current study is aimed at developing the Japanese version of the State Self-Compassion Scale and extending previous findings in the U.S. by showing measurement invariance across sexes and demonstrating the construct validity of this scale. Across two studies, the bifactor exploratory structural equation modeling representation of the SSCS-J showed excellent fit in which a single global factor and most of (...) the specific factors were well defined. Study 1 further provided evidence for the measurement invariance across sexes. The SSCS-J was related with higher trait self-compassion and lower fear of and negative beliefs about self-compassion. In Study 2, participants who were instructed to be self-compassionate reported higher scores in the SSCS-J relative to those in the control condition. These results attest to the replicability of the factor structure of the SSCS in Japan and provide further evidence for the construct validity of this scale. (shrink)

Finding truthmakers for negative truths has been a problem in philosophy for a long time. I will present and discuss the solution to this problem offered by Bertrand Russell, Raphael Demos, D. M. Armstrong, and myself. I will argue that some negative truths do not require truthmakers and that truthmakers for the other negative truths are the entities that these negative truths imply exist. I will also argue that truthmakers for general truths of the form, only X, Y, Z, and (...) etc. are F's, are the sum of each X, Y, Z, and etc.'s being F, and hence that sometimes truthmakers do not necessitate truths. (shrink)

The emerging critique of alternative food networks (AFNs) points to several factors that could impede the participation of low-income, minority communities in the movement, namely, spatial and temporal constraints, and the lack of economic, cultural, and human capital. Based on a semi-experimental study that offers 6 weeks of free produce to 31 low-income African American households located in a New Orleans food desert, this article empirically examines the significance of the impeding factors identified by previous scholarship, through participant surveys before, (...) during, and after the program. Our results suggest economic constraints are more influential in determining where the participants shop for food than spatial and temporal constraints, and the study participants exhibit high levels of human and cultural capital regarding the purchase and consumption of locally grown produce. We also find them undeterred by the market’s predominantly White, middle-class cultural social space, which leads us to question the extent to which cultural exclusivity discourages their participation in AFNs. For all five factors we find that the constraints posed to accessing the local food market were not universal but varied among the participants. Finally, the study reveals some localized social constraints, fragmented social ties in particular, as a possible structural hurdle to engaging these residents in the alternative market in their neighborhood. Conclusions point to the need for a multi-dimensional and dynamic conceptualization of “food access.”. (shrink)

Pupil contagion is the phenomenon in which an observer’s pupil-diameter changes in response to another person’s pupil. Even chimpanzees and infants in early development stages show pupil contagion. This study investigated whether dynamic changes in pupil diameter would induce changes in infants’ pupil diameter. We also investigated pupil contagion in the context of different faces. We measured the pupil-diameter of 50 five- to six-month-old infants in response to changes in the pupil diameter of upright and inverted faces. The results showed (...) that in the upright presentation condition, dilating the pupil diameter induced a change in the infants’ pupil diameter while constricting the pupil diameter did not induce a change, and pupil contagion occurred only in the upright face presentation, and not in the inverted face presentation. These results indicate the face-inversion effect in infants’ pupil contagion. (shrink)

Why has right-wing activism in Japan, despite its persistence throughout the postwar era, only gained significant traction recently? Focusing on the Zaitokukai, an anti-Korean movement in Japan, this article demonstrates how the new Far Right were able to popularize formerly stigmatized right-wing ideas. The Zaitokukai represents a political group distinct from the traditional right and reflective of new Far Right movements spreading worldwide. In Japan, concerns about the growing influence of South Korea and China in the 1980s as well as (...) the decline of left-wing norms opened up a discursive opportunity for the new Far Right. By framing Korean postcolonial minorities as undeserving recipients of social welfare benefits, the Zaitokukai mobilized perceptions of threat that has continued to powerfully influence public perceptions of Koreans even following the group’s organizational decline. While past research has focused on the new Far Right’s political influence, this article stresses their roles as ideological entrepreneurs. (shrink)

The human ability to flexibly discover alternatives without fixating on a known solution supports a variety of human creative activities. Previous research has shown that people who discover an alternative procedure relax their attentional bias to information regarding the known solutions just prior to the discovery. This study examined whether the difference in the distribution of attention between the finders and non-finders of the alternative procedure is observed from the phase of solving the problem using the trained procedure. We evaluated (...) the characteristics of the finders' distribution of attention in situations where problem solving using a trained procedure was successful. This aspect has been little examined in previous research. Our study obtained empirical evidence for the fact that, compared to non-finders, finders pay more attention to information unrelated to the trained procedure acquired through knowledge and experience, even time when using a trained procedure. We also confirmed that this difference does not exist from the beginning of the task, but emerges during repeated use of familiar procedures. These findings indicate that in order to find an alternative procedure, one should not only divert attention from a familiar procedure just before the discovery but also pay a certain amount of attention to information unrelated to the familiar procedure even when the familiar procedure is functioning well. (shrink)

An emerging concept is that quiescent mature skeletal cells provide an important cellular source for bone regeneration. It has long been considered that a small number of resident skeletal stem cells are solely responsible for the remarkable regenerative capacity of adult bones. However, recent in vivo lineage‐tracing studies suggest that all stages of skeletal lineage cells, including dormant pre‐adipocyte‐like stromal cells in the marrow, osteoblast precursor cells on the bone surface and other stem and progenitor cells, are concomitantly recruited to (...) the injury site and collectively participate in regeneration of the damaged skeletal structure. Lineage plasticity appears to play an important role in this process, by which mature skeletal cells can transform their identities into skeletal stem cell‐like cells in response to injury. These highly malleable, long‐living mature skeletal cells, readily available throughout postnatal life, might represent an ideal cellular resource that can be exploited for regenerative medicine. (shrink)

BackgroundFinancial interactions between pharmaceutical companies and physicians lead to conflicts of interest. This study examines the extent and trends of non-research payments made by pharmaceutical companies to board-certified allergists in Japan between 2016 and 2020.MethodsA retrospective analysis of disclosed payment data from pharmaceutical companies affiliated with the Japanese Pharmaceutical Manufacturers Association was conducted. The study focused on non-research payments for lecturing, consulting, and manuscript drafting made to board-certified allergists from 2016 to 2020. We performed descriptive analyses on payment data. Trends (...) were analyzed using generalized estimating equation models.ResultsOf the 3,943 board-certified allergists, 2,398 (60.8%) received non-research payments totaling $43.4 million over five years. Lecturing fees comprised 85.7% ($37.2 million) of the total payment amounts. For allergists who received at least one payment, the median amount per allergist was $3,106 (interquartile range: $966 – $12,124), in contrast to a mean of $18,092 (standard deviation: $49,233) over the five-year span. The top 1% and 10% of these allergists accounted for 20.8% and 68.8% of all non-research payments, respectively. The annual payment amounts significantly increased by 7.2% annual increase (95% CI: 4.4 – 10.0%, p < 0.001) each year until 2019, but saw a significant decrease in 2020 amid the COVID-19 pandemic.ConclusionThe majority of allergists received non-research payments, with a notable concentration among a small group. Payments increased annually until the pandemic’s onset, which coincided with a substantial decrease. Further research is needed to explore the implications of these financial interactions on clinical practice and patient care in Japan. (shrink)

Endosteal stem cells are a subclass of bone marrow skeletal stem cell populations that are particularly important for rapid bone formation occurring in growth and regeneration. These stem cells are strategically located near the bone surface in a specialized microenvironment of the endosteal niche. These stem cells are abundant in young stages but eventually depleted and replaced by other stem cell types residing in a non‐endosteal perisinusoidal niche. Single‐cell molecular profiling and in vivo cell lineage analyses play key roles in (...) discovering endosteal stem cells. Importantly, endosteal stem cells can transform into bone tumor‐making cells when deleterious mutations occur in tumor suppressor genes. The emerging hypothesis is that osteoblast‐chondrocyte transitional identities confer a special subset of endosteal stromal cells with stem cell‐like properties, which may make them susceptible for tumorigenic transformation. Endosteal stem cells are likely to represent an important therapeutic target of bone diseases caused by aberrant bone formation. (shrink)

法実証主義の現代的展開として法多元主義を位置づけるとともに、社会保障と自衛官合祀訴訟という個別の題材、さらに、組織論にもアプローチ。グローバル化がもたらす国家法と非国家法が交錯する世界を読み解く法理論 。.

Principles of Brain Evolution (Striedter 2005) places little emphasis on natural selection. However, one cannot fully appreciate the diversity of brains across species, nor the evolutionary processes driving such diversity, without an understanding of the effects of natural selection. Had Striedter included more extensive discussions about natural selection, his text would have been more balanced and comprehensive.

In the present paper I try to show that ethical principles of medical activities in general can be adequately applied to medical activities for the patient in his terminal stage. For this objective, I shall argue first what are the principles and rules of medical activities in general, and then show how these can be applied to palliative medicine.

This study examined whether 8-month-old infants’ hemodynamic responses in the temporal region were modulated by repeated presentation of “Peekaboo” by using functional near-infrared spectroscopy. Previous studies have shown that infants’ temporal region responds to faces. A recent electroencephalography study showed that the neural activity of infants was modulated by repeated presentation of “Peekaboo.” Some fNIRS studies also revealed that the movie of “Peekaboo” activated the hemodynamic response of the temporal region in infancy. However, no studies have shown the hemodynamic modulation (...) of the temporal region according to the repeated presentation of “Peekaboo” in infants. In order to examine whether the hemodynamic responses of the temporal region were modulated by repeated presentation of “Peekaboo,” we compared the activity of the temporal region between the early and late trials. We set long and short delays before face-presentation. The results showed that the concentration of oxy-hemoglobin in the right occipitotemporal region in both conditions increased after the presentation of “Peekaboo” relative to the baseline. Moreover, in the long delay condition, the hemodynamic modulation of the right occipitotemporal region was induced according to the repeated presentation of “Peekaboo” in infants. (shrink)

A comparative analysis was made of the public's attitudes toward the use of animals in scientific research in 15 different nations. The intensity of opposition to animal research was found to vary from relatively low levels in Japan and the United States to much higher levels in France, Belgium, and Great Britain. More women than men were opposed to animal research in all 15 nations. Scientific knowledge, or the lack of knowledge, was not found to have a consistent relationship with (...) attitudes toward animal research. Concern about the environment was found to be related to opposition to animal research in some western European nations, in particular West Germany. Cluster analysis was used to group the nations into four patterns based on intensity of opposition, level of opposition, gender differences in opposition, and the relationship between attitudes toward animal research and both environmental concern and scientific knowledge. (shrink)

We show that if a class K of finite relational structures is closed under quasi-substructures, then there is no saturated K-generic structure that is superstable but not ω -stable.

武士道の代表的書とされる『葉隠』が世に広まったのは太平洋戦争直前、「忠臣蔵」はサラリーマン化した武士への庶民の面当て、卑怯な考えとして『孫子』を忌避した新井白石、殉死は江戸時代初期の異常現象―。太平記 、甲陽軍艦といった古典から橋川文三、三島由紀夫まで、武士道がいかに歪曲・誤解されてきたのかを様々なエピソードを交えて解説する、思いもよらぬ事実が満載の本。.

The standing screens on the title is the oldest work extant of KANO Motonobu's work as folding screens of thick colored flowers and birds with golden background. This thesis designates that the scenery and the motif of the work are in correspondence with both descriptions of the scenery of Pure Land in several Buddhist scriptures and the design of actual gardens. Firstly, a peacock on the right hand screen is focused to indicate the bird connotes the elements of auspicious birds (...) in Buddhism, such as Mahamayuri and Kalavinka.Secondly, the elements of the scenery in the work, such as the four seasons at the same time ∼ the depiction of perpetuity ∼ and the existence of a pond, are identified with the description of Pure Land in Kwan-mu-liang-shou-ching and Ta-wuliang-shou-ching. These elements of the garden in the work are placed similarly to the Pure Land style gardens, which are illustrated in "Center and Surrounds of Kyoto" 's. In consideration of the above factors, the conclusion that, in the work, KANO Motonobu succeeded to portray the ideal garden by combining the scenery of Pure Land and that of actual gardens, is drawn. (shrink)

Culture is a demanding word, particularly when it is used in the context of the contemporary academic discipline of international relations . It is often employed in order to distinguish one identity from another, allegedly illuminating idiosyncrasies embedded in a particular society or group of people. The essentialized understanding of culture is also detectable in the case of the current debate on the non-Western international relations theories . Non-Western politicians and scholars often employ the term culture in order to distinguish (...) their values from alleged Western values. However, culture has another important function mainly advanced by a left-wing Kyoto School philosopher Tosaka Jun, that is, culture as a mirror for critical reflection for morality . This article is based on Tosaka's argument that culture has an important function for moral reflection beyond that of a mere means to identify one's distinctiveness from the West, and it criticizes Japan's soft power diplomacy or the total absence of it from that point of view. It also argues that this absence is the result of the soft power discourse's over-simplified interpretation of culture that results in confrontation between the West and the rest, particularly when it is employed in non-Western IRT discourses. Towards the end, I examine Miyazaki Hayao's films, Princes Mononoke in particular, as examples of cultural works facilitating a moment of critical reflection, and I extract embedded messages of relevance to critical reflection on contemporary IR literature, particularly non-Western literature. (shrink)

Chatbots powered by large language models (LLMs) are increasingly capable of engaging in what seems like natural conversations with humans. This raises the question of whether we should interact with these chatbots in a morally considerate manner. In this chapter, we examine how to answer this question from within the normative framework of virtue ethics. In the literature, two kinds of virtue ethics arguments, the moral cultivation and the moral character argument, have been advanced to argue that we should afford (...) moral treatment to social robots. However, we propose a moral character argument against the view that we should afford moral treatment to LLM-based chatbots drawing on the notion of practical wisdom. Practical wisdom in this context consists in the skill to discern genuine and artificial sociality. Drawing on ideas from phenomenological philosophy, we argue that this involves the ability to distance oneself from direct social perception and the ability to widen one’s awareness over one’s apparently social interactions. We conclude by suggesting that this skill is a kind of technomoral wisdom required to live well with advanced, social AI systems. (shrink)