Emotion recognition is an important part of building an intelligent human-computer interaction system and plays an important role in human-computer interaction. Often, people express their feelings through a variety of symbols, such as words and facial expressions. A business ecosystem is an economic community based on interacting organizations and individuals. Over time, they develop their capabilities and roles together and tend to develop themselves in the direction of one or more central enterprises. This paper aims to study a multimodal ER (...) method based on attention mechanism. It analyzes the current emotional state of consumers and the development direction of enterprises through multi-modal ER of human emotions and analysis of market trends, so as to provide the most appropriate response or plan. This paper firstly describes the related methods of multimodal ER and deep learning in detail, and briefly outlines the meaning of enterprise strategy in the business ecosystem. Then, two datasets, CMU-MOSI and CMU-MOSEI, are selected to design the scheme for multimodal ER based on self-attention mechanism. Through the comparative analysis of the accuracy of single-modal and multi-modal ER, the self-attention mechanism is applied in the experiment. The experimental results show that the average recognition accuracy of happy under multimodal ER reaches 91.5%. (shrink)

There are generally two controversial issues over Kant's solution to the free will problem. One is over whether he is a compatibilist or an incompatibilist and the other is over whether his solution is a success. In this paper, I will argue, regarding the first controversy, that “compatibilist” and “incompatibilist” are not the right terms to describe Kant for his unique views on freedom and determinism; but that of the two, incompatibilist is the more accurate description. Regarding the second controversy, (...) I will argue that Kant's solution to the free will problem is not a success because his effort in making the effects of freedom part of the field of appearance has made his solution incoherent and ambiguous. Despite this, I argue that Kant's attempt to solve the free will problem is groundbreaking because he at least has separated freedom from the dominance of determinism. (shrink)

[174 pages] This third book in the series 霍耐特选集 [Selected Works of Axel Honneth] is a Chinese translation of Axel Honneth’s and Jacques Rancière’s Anerkennung oder Unvernehmen? Eine Debatte directly from the German.

Mou Zongsan incorrectly uses Kant's practical reason to interpret Confucianism. The saying that "what is it that we have in common in our minds? It is the il 理 (principles) and the yi 义 (righteousness)" reveals how Mencius explains the origin of il and yi through a theory of common sense. In "the li and the yi please our minds, just as the flesh of beef and mutton and pork please our mouths," "please" is used twice, proving aesthetic judgment is (...) necessary to understanding Mencius. An analysis of Zhu Xi and Wang Yangming's ideas will show that Confucianism should be interpreted by appealing to aesthetic judgment, and a discussion of Kant's theory of judgment and Gadamer's critique of Kant's theory will support the same point. The conclusion is that Chinese moral philosophy should be interpreted through aesthetic judgment. /// 牟宗三以康德实践理性解说儒学是一错误思路。"心之所同然者何也?谓理 也，义也", 表明孟子以共通感论述理义来源, "理义之悦我心，犹当拳之悦我口" 两用 "悦" 字，证明应当以直感判断力解说孟子。分析朱子、阳明的一些言论证 明以直感判断力解说儒学则若合符节; 并引述康德关于判断力的相关学说、伽达 默尔对康德的批评支持上述论点; 从而主张，中国道德哲学宜以直感判断力来解 释。. (shrink)

Based on its productionguideline, organic agriculture has set foritself the goals of minimizing all forms ofpollution and maintaining sustainability of thefarming system. By striving for these goals,organic farming meets the demands of anincreasing number of consumers who are criticalof conventional production methods. This papergives an overview of the present state of theart in the different issues. Possibilities ofand limitations in performing the self-aimedgoals under the basic standards of organicagriculture are discussed. Concerningenvironmental protection, in general, the riskof adverse environmental effects is (...) lower withorganic than with conventional farming methods,though not necessarily so; with reference tosoil fertility and nutrient management, organicfarming is suited to improve soil fertility andnutrient management markedly on the farm level;regarding biodiversity, comparison studies showthat organic farming has more positive effectson biodiversity conservation; in relation toproduct quality, under the basic standards oforganic farming, there is no sufficientevidence for a system-related effect on productquality due to the production method. (shrink)

This essay tries to analyze the contention, conversation and conjunction between Confucian and Buddhism through debates on loyalty and filial piety from the Three Kingdoms to the Tang Dynasty, and to explain the influence on Buddhist loyalty and filial piety by the Confucian thoughts.

[232 pages] This second book in the series 霍耐特选集 [Selected Works of Axel Honneth] is a Chinese translation of Axel Honneth’s Vivisektionen eines Zeitalters: Porträts zur Ideengeschichte des 20. Jahrhunderts directly from the German.

The cause of Chinese philosophy has made significant progress since it began to reform three decades ago. However, Chinese philosophy also faces many problems. Shaken by current market economic forces, it now confronts a huge challenge in taking on its mission of raising questions, both theoretical and practical, and responding to them using the methods of philosophy. This article analyzes developments and problems in the three sub-disciplines of philosophy: Marxist philosophy, the history of Chinese philosophy and foreign philosophies. Using this (...) framework, it will purposefully address the great historical responsibility facing Chinese philosophers. (shrink)

[232 pages] This first book in the series 霍耐特选集 [Selected Works of Axel Honneth] is a Chinese translation of Axel Honneth’s Pathologien der Vernunft: Geschichte und Gegenwart der Kritischen Theorie directly from the German.

Despite advancements in human research ethics and the growing significance of Research Ethics Board (REB) members, educational opportunities specifically tailored to their needs remain lacking in many countries. In response to this gap, our research aims to understand the demographics, needs, and preferences for educational opportunities of REB members in Canada. We conducted a survey that found REB demographics to be diverse and have different perceptions of their roles on topics such as the evaluation of the scientific merit of studies (...) and responsibilities to stakeholders. We found that REB members in general prefer online tutorials and webinars for their education. Educators interested in facilitating the development of future training programs should consider the needs and preferences of REB members outlined in this publication. (shrink)

Part of current pragmatics research aims at opening up new avenues of inquiry by revisiting and revising some of its central topics and keywords, such as implicature, explicature, truth, varieties of meaning, meaning inference, relevance, politeness, and face. This review article attempts to contribute to this endeavor by making some comments on and beyond Kecskes and Horn's Explorations in Pragmatics: Linguistic, Cognitive and Intercultural Aspects. With reference to certain Chinese linguistic and interactional actualities, this paper argues, among other things, that (...) a speaker who conveys some truth to a hearer does not necessarily mean that the speaker is committed to that truth, that people with little social power may also manipulate the power of words in actual interaction, and that when it comes to making politeness evaluations, what one does may turn out to be more important and decisive than what one says. (shrink)

The globalization in business and tourism becomes crucial more and more for the economical sustainability of local communities. In the presence of an epidemic outbreak, there must be such a decision on the policy by the host community as whether to accept visitors or not, the number of acceptable visitors, or the condition for acceptable visitors. Making use of an SIRI type of mathematical model, we consider the influence of visitors on the spread of a reinfectious disease in a community, (...) especially assuming that a certain proportion of accepted visitors are immune. The reinfectivity of disease here means that the immunity gained by either vaccination or recovery is imperfect. With the mathematical results obtained by our analysis on the model for such an epidemic dynamics of resident and visitor populations, we find that the acceptance of visitors could have a significant influence on the disease’s endemicity in the community, either suppressive or supportive. (shrink)

The development of philosophy in contemporary China requires correct understanding and solving prominent practical problems in China’s process of social development, providing proper rational thinking, value ideal and life orientation for the Chinese, and playing its role of guiding, regulating and promoting social progress. To achieve the goal, philosophy needs to shift from “system consciousness” to “problem consciousness,” so as to fulfill a paradigm transformation; to shift from “local horizon” to “world horizon,” so as to expand the horizon of our (...) philosophy; and to shift from the tripartite division of Chinese, Western and Marxist philosophies to a “common horizon” for the three, so as to gradually establish the concept of “macro-philosophy.”. (shrink)

Resumo: O setor de vestuário trouxe novas chances de desenvolvimento ao mercado, como resultado do avanço da sociedade e da expansão da cultura e da arte. Além de ter alto valor decorativo, como sua extensão e ampliação, o desempenho do vestuário também pode existir, independentemente, como uma arte. No entanto, ao moldar a imagem artística do desempenho do vestuário, o foco principal concentra-se na apresentação de imagens externas, sem a expressão das características rítmicas e conotativas dos movimentos corporais, o que (...) não apenas enfraquece o efeito visual do desempenho, mas também afeta sua integridade e continuidade. Portanto, compreender a relação entre o desempenho do vestuário e o corpo e promover sua integração e penetração mútuas são de grande valor e importância, para o desenvolvimento atual da arte visual. A filosofia do corpo é uma disciplina filosófica que explora o corpo e as experiências corporais. Ela preocupa-se com a maneira como o corpo percebe e existe. Isso pode encorajar atores e figurinistas a considerarem como as roupas moldam e comunicam a identidade social e pessoal, além de observarem como a performance do figurino pode explorar a diversidade e a mudança de identidade. O presente artigo explica a relação entre o corpo e a estética, com base na história do desenvolvimento, na função e no valor do desempenho das roupas, combinados com a teoria da filosofia do corpo, a fim de estudar mais profundamente a relação entre o desempenho do vestuário e o corpo, de sorte a aumentar a eficácia do desempenho do vestuário. Do ponto de vista da filosofia do corpo, trata-se de um fator indispensável no desempenho do figurino. Este, por sua vez, pode alcançar a expressão artística do corpo, sendo que ambos interagem e se promovem. A íntima relação entre os dois tem importância significativa para o alcance de níveis mais elevados de representação visual, no desenvolvimento das atividades estéticas. (shrink)

Causality is the most basic connection, rule, logic and fact of the phenomenal world, so finding the causal connection between things and utilising it to achieve the goal of avoiding harm and ultimately attaining happiness are the fundamental motivation for all human intellectual activities. This paper first points out that any causal inference in any field can and should be analysed from three dimensions: cause, condition and result. And then it introduces the six-causes doctrine, ten-causes doctrine, four-conditions doctrine and five-effects (...) doctrine in Buddhist philosophy. This provides a complete analytical framework for causal reasoning, and any causal analysis in any field can be integrated into this comprehensive framework for study. (shrink)

I distinguish two types of ethical efforts. One of them can be called ideological efforts in morality, which begins with the quest for truth. Once in possession of the truth, people can make moral laws and apply them to a society, demanding that all members of the society abide by them. The other may be called sentimental education, which depicts the formation of morality as being based on sentiments in this way: people live in an intimate relationship to foster a (...) sentiment of trust, develop their propriety sense in regard to a certain relationship, and formulate it as a moral law. In the context of global ethics, I hold that the fundamental momentum in morality is driven by sentimental education, while ideological efforts in morality can only play a complementary role. (shrink)

This article offers a comparative study of the views of Alexis de Tocqueville and those of several Chinese thinkers of the late Ming dynasty (1368–1644)—primarily Gu Yanwu, Huang Zongxi, Wang Fuzhi—on the socio-political processes of centralization. My central claim is that their views of political centralization and of the decentralized polycentric society that preceded it in their respective countries exhibit a remarkable array of analogous structural features. More specifically, both Tocqueville and his Chinese counterparts perceive in centralization an inherent unsustainability (...) driven by its self-destructive nature: since the foundation and strength of statism depends on its social resources, the centralization of power inevitably results in the weakening of its own basis. I conclude that through their nuanced reinterpretation of self-interest, both parties advocate a “small-community-oriented communitarianism” instead of the increasingly centralized modern state. (shrink)

In recent years, attention to researchers’ scientific misconduct has increased dramatically. Although existing research reflects a shared value that occupational calling is an ethical good (i.e., being more likely to make ethical choices), no empirical study has yet examined the ethical outcomes of occupational calling. Drawing on the integrated ethical decision-making model (I-EDM), this study first investigated _whethe_r occupational calling inhibits researchers’ unethical decision-making. Secondly, it examined _why_ and _when_ occupational calling relates to researchers’ unethical decision-making. The findings from a (...) four-wave survey, with 257 researchers working in research roles in universities in China, reveal that occupational calling (time 1) inhibits researchers’ unethical decision-making (time 4). Moral disengagement (time 3) provides an explanation for the negative link between occupational calling (time 1) and unethical decision-making (time 4). The moderated mediation analysis further shows that the inhibitory effect of occupational calling (time 1) on researchers’ unethical decision-making (time 4) disappears when the work-unit structure (time 2) is perceived to be organic. These findings provide meaningful theoretical and practical implications for research and practice. (shrink)

As the main literature of socio-economic history, local gazetteers display the dynamic process of local socio-economic structuring and reflect local conflicts among various interest groups. Focusing on local gazetteers in Wanzai County of Jiangxi Province from the Qing to the Republic, this essay shows how local literati played an active role in constructing their local community. These gazetteers reflected the complicated power relations, especially the conflict between the natives and immigrants, and they themselves became the important part of the process (...) of local power reproduction and culture construction. (shrink)

This essay attempts to compare Kant’s better man and the Confucian junzi in the Zhongyong, and argues that Kant’s idea of the better man, which expresses human self-improvement in ultimate freedom, is in fact a conception very similar to that of the Confucian junzi, which denotes an ideal human being in cheng. Kant attributes the lack of emphasis on self-improvement in Western culture to the Christian conception of grace, and demonstrates the possibility of self-improvement on the ground of ultimate freedom. (...) We may call this treatment “the Confucian solution” in Kant’s thought. My intention is to explicate the conceptual commonality between the better man and the junzi and demonstrate the Confucian element in Kant’s religious thought. (shrink)

In China, a prominent case exists wherein a medically fit woman filed a lawsuit against a hospital for denying her request to undergo oocyte cryopreservation. She contended the hospital had infringed upon her rights. This paper focuses on medicalization and gender equality to discuss whether or not a hospital can infringe upon a woman's rights. We believe elective oocyte cryopreservation is not a medical treatment and it may lead to an overwhelming utilization of extensive medical resources. Reproductive medicine may face (...) the risk of resource commercialization due to the practice of selective egg freezing. There are physiological disparities between males and females. The ability of men to cryopreserve sperm does not necessarily extend to a woman's capacity for oocyte cryopreservation. We contend that the application of this technology should continue to adhere to the principle of prudence. (shrink)

This research investigates and analyzes the integration of traditional Chinese music into contemporary music education systems in Ji'an City, Jiangxi Province, China, from an evolutionary perspective. It emphasizes the importance of traditional music education in preserving cultural heritage, fostering creativity, and enhancing holistic student development within the framework of imaginative culture. The study employs a structured approach using the PRISMA methodology to systematically review relevant literature and assess the current status of music education in Ji'an, focusing on course implementation, teacher (...) qualifications, and educational outcomes. The results reveal significant challenges, including the need for qualified educators, standardized curriculum frameworks, and resource allocation for traditional music. It also highlights the positive impacts of traditional music on students' aesthetic, cognitive, and social development. The discussion integrates these findings with existing literature, suggesting the need for innovative pedagogical strategies and technology integration to enhance traditional music education's effectiveness and appeal. The study concludes that effectively integrating traditional Chinese music into Ji'an's education system can promote cultural preservation and improve educational quality, recommending targeted reforms to address the identified challenges. This research contributes valuable insights for educators, policymakers, and researchers, advocating for a comprehensive and culturally responsive approach to music education. (shrink)

[The statement] A ^ Ā is doubtlessly a logical contradiction in terms of formal logic. However, according to dialectics this is a state which the contradiction in the essence of a thing experiences in the process of development — a state of qualitative change of being "at once this and that." A contradiction under such circumstances is an important object of dialectical studies. And such a state of affairs actually exists in real life; a thing tends to experience such a (...) state when it changes into its opposite. The contradictory aspects experiencing such a state both conform to reality. Therefore A ^ Ā is a logical contradiction and a dialectical contradiction as well. The two types of contradictions are actually the two manifestations of the same contradiction in different contexts. Or, in other words, they are the different points of view and approaches of two kinds of logic toward the same contradiction. Obviously, in distinguishing problems we must first make clear the two different kinds of logic, or, the two different methods in approaching contradictions, rather than distinguishing between two types of contradictions. That is to say, what we must distinguish first is logic and not contradiction. In different categories of logic, contradiction takes on different character. (shrink)

Xiong Shili / Li Shuangqing zhu -- Zhang Junmai / Jiang Yongzhen zhu -- Jiang Zhongzheng / Wu Jiping zhu.

This article aims to understand the most fundamental operating principles of the phenomenal world and figure out how phenomena within the phenomenal world are interconnected. Causality is the most basic connection, rule, logic and fact of the phenomenal world, since everything in the phenomenal world is originally in the interconnection of three elements: cause, condition and effect. Finding the causal connection between things and utilising it to achieve the goal of avoiding harm and ultimately attaining happiness is the fundamental motivation (...) for all human intellectual activities, including scientific research, philosophical discernment, and religious beliefs. The article gives a universal definition of causation as the primordial, underlying, transcendental, inherent, intrinsic, ultimate, essential, fundamental, inevitable, invariable, timeless, universal, complex, multidimensional, dynamic connection, law, logic, and fact among the three elements of cause, condition and result in the phenomenal world. The article explains in detail why the foregoing definition is universal from both ontological and epistemological perspectives. (shrink)

The impact of bilingual education and bilingual experience on working memory has been an important and controversial issue in the field of psycholinguistics. Taking Chinese-English bilinguals as an example, this study aims to investigate the differences in emotional working memory between proficient and non-proficient bilinguals by using delayed matching-to-sample task paradigm and more complex n-back task in the context of emotion. The results show that proficient bilinguals have better performance on both of the two working memory tasks than non-proficient bilinguals, (...) and the advantage effects were more apparent under high memory load conditions. Besides, the negative emotion context has a positive impact on complex n-back tasks. This study supports the notion that bilingual experience can promote the development of an individual’s cognitive ability and enable individuals to possess more advantages in working memory even in the presence of emotional distractions. (shrink)

Extensive conflicts of interest at both individual and institutional levels are identifiable in scientific research and healthcare in China, as in many other parts of the world. A prominent new case from China is He Jiankui’s experiment that produced the world’s first gene-edited babies and that raises numerous ethical, political, socio-cultural, and transnational questions. Serious financial and other COI were involved in He’s genetic adventure. Using He’s infamous experiment as a case study, this paper explores the wider issue of financial (...) and other COI in scientific research and healthcare in China, especially institutional conflict of interest and policy-related COI. Taking a socio-ethical perspective, it examines China’s state policies and its massive efforts to transform and commercialize scientific research, the lack of policies and oversight mechanisms for regulating COI, as well as major ethical issues arising from COI including the undermining of public trust. Some practical suggestions are offered for institutional reform and institutional development so that COI, particularly ICOI, can be avoided or more effectively managed in scientific research in China. (shrink)

We discuss the relationships between effect algebras with the Riesz Decomposition Property and partially ordered groups with interpolation. We show that any σ-orthocomplete atomic effect algebra with the Riesz Decomposition Property is an MV-effect algebras, and we apply this result for pseudo-effect algebras and for states.

In transitional economies, the governing central authorities impose heavy regulatory burdens on firms, which results in great costs for business in terms of time, resources, and other constraints. However, quality assurance through decentralized institutions (such as private certified management standards) is rapidly becoming more prevalent. This study examines the contingent implications that such decentralized institutions have for centralized regulation by focusing on the relationship between international certifications and regulatory burdens. As two prominent features of the institutional environment in emerging economies, (...) the threat of competition from the informal sector and corruption may influence the relationship between international certifications and regulatory burdens. These features are therefore examined in terms of their moderating roles. The study draws on institutional and signaling theories to interpret data from a survey conducted by the World Bank in China in 2012. The empirical results show that international certification is negatively associated with regulatory burdens. This relationship is strengthened by the threat of competition from the informal sector, but mitigated by a corrupt business environment. Our study contributes to the institutional literature and to research on international certifications, and it has implications for both business management and governmental policy. (shrink)

This paper addresses the issue of the relationship between Ralph Johnson’s idea of dialectical tier and the critical scrutiny function in argument. We first give a concise articulation of the critical view of argument, and then probe into both the apparent similarities and deep discrepancies between the critical view of argument and Johnson’s views on the dialectical tier and manifest rationality. On that basis, we disprove the conjecture that the presence of a dialectical tier indicates that the thesis in argument (...) is critically established. However, we also urge to bridge together the critical view of argument and Johnson’s theory of argument, and thereby to make the dialectical tier critical in nature. We argue that this could be a promising proposal, and conclude with some remarks on exploring the critical dimension within our current study of argument. (shrink)

Irresponsible research practices damaging the value of science has been an increasing concern among researchers, but previous work failed to estimate the prevalence of all forms of irresponsible research behavior. Additionally, these analyses have not included articles published in the last decade from 2011 to 2020. This meta-analysis provides an updated meta-analysis that calculates the pooled estimates of research misconduct and questionable research practices, and explores the factors associated with the prevalence of these issues. The estimates, committing RM concern at (...) least 1 of FFP and QRPs concern 1 or more QRPs, were 2.9% and 12.5%, respectively. In addition, 15.5% of researchers witnessed others who had committed at least 1 RM, while 39.7% were aware of others who had used at least 1 QRP. The results document that response proportion, limited recall period, career level, disciplinary background and locations all affect significantly the prevalence of these issues. This meta-analysis addresses a gap in existing meta-analyses and estimates the prevalence of all forms of RM and QRPs, thus providing a better understanding of irresponsible research behaviors. (shrink)

This study describes the results of experiments motivated by an attempt to understand spectral processing in the cerebral cortex (DeValois and DeValois, 1988; Pribram, 1971, 1991). This level of inquiry concerns processing within a restricted cortical area rather than that by which spatially separate circuits become synchronized during certain behavioral and experiential processes. We recorded neural responses for 55 locations in the somatosensory (barrel) cortex of the rat to various combinations of spatial frequency (texture) and temporal frequency stimulation of their (...) vibrissae. The recordings obtained from single and multi-unit bursts of spikes were mapped as surface distributions of local dendritic potentials. The distributions showed a variety of patterns that are asymmetric with respect to the spatial and temporal parameters of stimulation, and were, therefore, not simply reflecting whisker flick rate. Next, a simulation of our results showed that these surface distributions of local dendritic potentials can be described by Gabor-like functions much as in the visual system. The results provide support for a model of distributed cortical processing that imposes a physiologically derived frame (the limited extent of a dendritic patch) and an anatomically derived (axonal) sampling of the distributed process. This combination provides a complex Gabor wavelet that encodes phase, which is necessary to processing such details as edges and texture in a scene. The synchronization across cortical areas that make the Gabor wavelet processes within restricted cortical areas available to one another (the binding problem) proceed at a ''higher order'' level of integration. Both levels of distributed processing accomplish computation in the conjoint spacetime and spectral domain. (shrink)

Green consumption values have been shown to motivate consumers to engage in green consumption practices. However, surprisingly little research has examined how green consumption values develop in young people. In the current study, we employed ecological socialization theory as a framework to investigate the process by which parents’ green consumption values shape similar values in their young adolescents. In Study 1, data from 722 Chinese families that included an early adolescent showed that both mothers’ and fathers’ green consumption values were (...) positively associated with early adolescents’ green consumption values, and this association was mediated by each parent’s environmentally responsible consumption behavior. Study 2 replicated the results of Study 1 using two waves of matched parent-adolescent data collected a month apart from another group of 477 Chinese families. Furthermore, Study 2 showed that the mediation process identified in Study 1 was evident only when there was a close parent–child relationship. These findings have implications for cultivating the green consumption values of today’s youth. The results also have heuristic value for future research on the ecological socialization and inter-generational transmission of pro-environmental values. (shrink)

Background and PurposeTranscranial direct current stimulation is an emerging non-invasive neuromodulation technique for focal epilepsy. Because epilepsy is a disease affecting the brain network, our study was aimed to evaluate and predict the treatment outcome of cathodal tDCS by analyzing the ctDCS-induced functional network alterations.MethodsEither the active 5-day, −1.0 mA, 20-min ctDCS or sham ctDCS targeting at the most active interictal epileptiform discharge regions was applied to 27 subjects suffering from focal epilepsy. The functional networks before and after ctDCS were (...) compared employing graph theoretical analysis based on the functional magnetic resonance imaging data. A support vector machine prediction model was built to predict the treatment outcome of ctDCS using the graph theoretical measures as markers.ResultsOur results revealed that the mean clustering coefficient and the global efficiency decreased significantly, as well as the characteristic path length and the mean shortest path length at the stimulation sites in the fMRI functional networks increased significantly after ctDCS only for the patients with response to the active ctDCS. Our prediction model achieved the mean prediction accuracy of 68.3% after the nested cross validation. The mean area under the receiver operating curve was 0.75, which showed good prediction performance.ConclusionThe study demonstrated that the response to ctDCS was related to the topological alterations in the functional networks of epilepsy patients detected by fMRI. The graph theoretical measures were promising for clinical prediction of ctDCS treatment outcome. (shrink)

The RNAi machinery is not only involved with post‐transcriptional degradation of messenger RNAs, but also used for targeting of chromatin changes associated with transcriptional silencing. Two recent papers determine the global patterns of gene expression and chromatin modifications produced by the RNAi machinery in fission yeast.(9, 10) The major sites include the outer centromere repeats, the mating‐type locus and subtelomeric regions. By comparison, studies of Arabidopsis heterochromatin also implicate transposons as a major target for silencing. Analyses of siRNA libraries from (...) Drosophila, nematodes and Arabidopsis indicate that major repeats at centromeres, telomeres and transposable elements are likely targets of RNAi. Also, intergenic regions are implicated as targets in Arabidopsis. BioEssays 27:1209–1212, 2005. © 2005 Wiley Periodicals, Inc. (shrink)