Background: With the coming of the Industrial Revolution, the levels of pollution grow significantly. This Technological development contributed to the worsening of shortness breath problems in great shape. especially in infants and children. There are many shortness breath diseases that infants and children face in their lives. Shortness of breath is one of a very serious symptom in children and infants and should never be ignored. Objectives: Along these lines, the main goal of this expert system is to help physician (...) in diagnosing and describe some common causes of shortness of breath in infants and children by diagnosing their cases through our expert system. Moreover, this system which we are presenting will give patient the appropriate diagnosis of disease and the treatment required. Methods: In this paper the strategy of the expert system for diagnosing a number of the existed shortness of breath in infants and children diseases such as (Asthma , Bronchiolitis, Viral Pneumonia, cough, Shortness of breath' dyspnea ', Epiglottitis, Croup, ABSCESS in the tonsil 'peritonsillar abscess', Bronchitis, Viral Bronchitis, Wheezing, sudden infant death syndrome 'SIDS' ) is introduced, an overview about the shortness of breath in children and infants diseases are delineated, the cause of diseases are sketched and the treatment of disease whenever conceivable is given . SL5 Object Expert System language was utilized for designing and implementing the proposed expert system. Results: The proposed shortness of breath in children and infants diseases diagnosis expert system was estimated by Medical students and they were satisfied with its result. Conclusions: The Proposed expert system is very useful for Respiratory physician, pediatrician, recently graduated physician, and for children's parents with shortness of breath problem. (shrink)

Two thought experiments are discussed which suggest, first, a geometric interpretation of the concept of a (say, vector) potential (i.e., as a kinematic quantity associated with a transformation between moving frames of reference suitably related to the problem) and, second, that, in a quantum treatment one should extend the notion of the equivalence principle to include not only the equivalence of inertial forces with suitable “real” forces, but also the equivalence of potentials of such inertial forces and the potentials of (...) suitable real forces. The two types of cancellation are physically independent of each other, because of the Aharonov-Bohm effect. Finally, we show that the latter effect itself can be understood “geometrically” as a kinematic effect arising upon the transformation between the two reference frames. (shrink)

إنَّ الخطاب الصوفي يتموقع في عرفان العقل العربي كأبرز الخطابات الروحية والفنية المؤثرة في الساحة الثقافية العربية، وهذا لما يمتلكه من شروط ومعايير خوَّلته أن يقتحم بمنجزه أسوار المشهد المعرفي الإنساني، من هذا المنطلق ستحاول هذه الدراسة الاقتراب من بعض قضاياه الضاربة في عمق هذا الخطاب، بوصفه يرسم العلاقة الحوارية بين اللغة الرمزية في بعدها المفهومي والمعرفي، المرتكزة على إمكانات الدلالة وإنتاج المعنى، وبين مفهوم المخيال الصوفي كبعد أنطولوجي/جمالي، يؤسِّس للعدسات التصوَّرية الملأى بالفضاءات الكاشفة والجامعة لمسارات إبداع المخيال الصوفي؛ المتجلية (...) أنوارُهُ وجودًا وشهودًا، والذي يشكّل في مجموعه بنية فاعلة في منظومة النسق العرفاني، ومحل إعراب هذا المخيال في إنتاج معنى منفتح يؤطر مفهوم العرفان الصوفي ويضبط إمكاناته المختلفة المنصهرة في بوتقةِ رؤيةٍ شاملة لمسارات الإبداع الروحي والنفسي للإنسان. إن بعض القضايا المطروحة في هذا الكتاب قد أسالت حبرا، وأثارت نقاشا لا يزال صداه إلى اليوم كـ " إشكالية الإنسان الكامل في الفكر الصوفي " و" جدل الحقيقة والشريعة في الفكر الصوفي " و" الرمزية الحرفية في الفكر الصوفي" خاصة عند محي الدين بن عربي، ومنها بعض القضايا التي حاولت تقديم رؤية فيها، انطلاقا من المعطى العرفاني الصوفي، كـ " الأبعاد العرفانية لخطاب الموت في الفكر الصوفي " و" عقلاء مجانين الصوفية بين خطاب الجنون وجنون الخطاب ". (shrink)

Although activated spinal cord glia contribute importantly to neuropathic pain, how nerve injury activates glia remains controversial. It has recently been proposed, on the basis of genetic approaches, that toll-like receptor 4 may be a key receptor for initiating microglial activation following L5 spinal nerve injury. The present studies extend this idea pharmacologically by showing that TLR4 is key for maintaining neuropathic pain following sciatic nerve chronic constriction injury. Established neuropathic pain was reversed by intrathecally delivered TLR4 receptor antagonists derived (...) from lipopolysaccharide. Additionally, -naltrexone, -naloxone, and -naloxone, which we show here to be TLR4 antagonists in vitro on both stably transfected HEK293-TLR4 and microglial cell lines, suppressed neuropathic pain with complete reversal upon chronic infusion. Immunohistochemical analyses of spinal cords following chronic infusion revealed suppression of CCI-induced microglial activation by -naloxone and -naloxone, paralleling reversal of neuropathic pain. Together, these CCI data support the conclusion that neuron-to-glia signaling through TLR4 is important not only for initiating neuropathic pain, as suggested previously, but also for maintaining established neuropathic pain. Furthermore, these studies suggest that the novel TLR4 antagonists -naloxone and -naloxone can each fully reverse established neuropathic pain upon multi-day administration. This finding with -naloxone is of potential clinical relevance. This is because -naloxone is an antagonist that is inactive at the -opioid selective receptors on neurons that produce analgesia. Thus, these data suggest that -opioid antagonists such as -naloxone may be useful clinically to suppress glial activation, yet -opioid agonists suppress pain. (shrink)

Chapman and colleagues make a compelling case for reforming the Common Rule to better protect group interests in genomics and data-centric research (Chapman et al. 2025). Drawing on insights from p...

--- 2. Peraḳim 3-4 -- 3. Peraḳim 5-6 --.

Public policies are designed to have an impact on particular societies, yet policy-oriented computer models and simulations often focus more on articulating the policies to be applied than on realistically rendering the cultural dynamics of the target society. This approach can lead to policy assessments that ignore crucial social contextual factors. For example, by leaving out distinctive moral and normative dimensions of cultural contexts in artificial societies, estimations of downstream policy effectiveness fail to account for dynamics that are fundamental in (...) human life and central to many public policy challenges. In this paper, we supply evidence that incorporating morally salient dimensions of a culture is critically important for producing relevant and accurate evaluations of social policy when using multi-agent artificial intelligence models and simulations. (shrink)

Understanding Javanese philosophy through wayang wong performance.

Volume 25, Issue 3, March 2025, Page 7-9.

Heritable monogenic maladies, the byproduct of single gene mutations, comprise a broad range of over 10,000 inborn afflictions (OMIM® 2023). Some of the more common monogenic disorders in question...

We consider a sequence of successively more restrictive definitions of abstraction for causal models, starting with a notion introduced by Rubenstein et al. (2017) called exact transformation that applies to probabilistic causal models, moving to a notion of uniform transformation that applies to deterministic causal models and does not allow differences to be hidden by the "right" choice of distribution, and then to abstraction, where the interventions of interest are determined by the map from low-level states to high-level states, and (...) strong abstraction, which takes more seriously all potential interventions in a model, not just the allowed interventions. We show that procedures for combining micro-variables into macro-variables are instances of our notion of strong abstraction, as are all the examples considered by Rubenstein et al. (shrink)

We interpret the (formal) postulates of measurement in quantum theory in terms of measurement procedures that can be done in the laboratory (at least in principle).

How do we ready ourselves to intervene responsively in the contingent situations that arise in co-designing to make change? How do we attune to group dynamics and respond ethically to unpredictable developments when working with 'community'? Participatory Design can contribute to social transitions, yet its focus is often tightly tuned to technique for designing ICT at the cost of participatory practice. We challenge PD conventions by addressing what happens as we step into a situation to alter it with others, an (...) aspect of practice that cannot be replicated or interchanged. We do so to argue that practices of readiness are constituted by personal histories, experiences, philosophies and culture. We demonstrate this political argument by giving reflexive accounts of our dimensions of preparation. The narratives here are distinct, yet reveal complementary theories and worldviews that shape PD ontologies. We have organized these around the qualities of punctuation and poise as a way to draw out some less easily articulated aspects of PD practice. (shrink)

Hastings Center Report, Volume 52, Issue S1, Page S89-S89, March‐April 2022.

The general subject of the book is the re-discovery of Maimonides’ Guide of the Perplexed by the Wissenschaft des Judentums movement in Germany of the nineteenth and beginning twentieth Germany. Since this movement is inseparably connected with religious reforms that took place at about the same time, it shall be demonstrated how the Reform Movement in Judaism used the Guide for its own agenda of historizing, rationalizing and finally turning Judaism into a philosophical enterprise of ‘ethical monotheism’. The study follows (...) the reception of Maimonidean thought, and the Guide specifically, through the nineteenth century, from the first beginnings of early reformers in 1810 and their reading of Maimonides to the development of a sophisticated reform-theology, based on Maimonides, in the writings of Hermann Cohen more then a hundred years later. (shrink)

Proceedings of a forum held in Austin, Tex., on Mother's Day, 1996.

El hombre crea su moral tomando en cuenta las aportaciones más íntimas de su espíritu. Así como la historia de la humanidad presenta una serie gradual y emocional de conquistas espirituales, así también la moral se ha logrado a través de la historia, pero siempre sobre el fundamento de la esencia humana, pues no cabe duda de que la jerarquía de los valores depende de cada ser humano. Ella orienta toda su conducta y señala sus grandes metas. El espíritu religioso (...) coloca, en primer término, a los valores de la religión, el moralista a los éticos, el pragmático a los útiles; el estético a las bellas artes, dando preferencia cada una a su valor favorito. (shrink)

Pero queda, a través de este devenir, la luz mosaica, las Tablas de la Ley, las sentencias del Talmud, las profecías de la Biblia. Este es el Tesoro del pueblo Judaico, el único que se ha conservado a través de los siglos; el que todavía suena en los momentos de la mayor angustia para la Humanidad y que vése conmovido por el impetuoso torrente de la vida contemporánea que exige nueva vitalidad en todos los aspectos de la existencia humana. DR. (...) ADALBERTO GARCÍA DE MENDOZA. (shrink)

Machine generated contents note: Cajal and Consciousness: Introduction. By PEDRO C. MARIJUAN1 -- Part I. Consciousness, One Hundred Years after Textura -- Progress in the Neural Sciences in the Century after Cajal (and the Mysteries -- That Remain). By THOMAS D. ALBRIGHT, THOMAS M. JESSELL, -- ERIC R. KANDEL, AND MICHAEL I. POSNER11 -- Part II. Biological Complexity and the Emergence of Consciousness -- Consciousness, Reduction, and Emergence: Some Remarks. -- By MURRAY GELL-MANN41 -- The Epistemic Paradox of Mind and (...) Matter. By HAROLD J. MOROWITZ50 -- The Conscious Cell. BY LYNN MARGULIS55 -- Complexity and Tinkering. By FRANCOIS JACOB71 -- Consciousness, the Brain, and Spacetime Geometry. By STUART HAMEROFF. 74 -- Consciousness, the Brain, and Spacetime Geometry: An Addendum-Some -- New Developments on the Orch OR Model for Consciousness. -- By ROGER PENROSE105 -- Part III. From Primary to Higher-level Consciousness -- Consciousness: The Remembered Present. By GERALD EDELMAN111 -- Consciousness and the Binding Problem. By WOLF SINGER123 -- Cajal on Neurons, Molecules, and Consciousness. By JEAN-PIERRE CHANGEUX 147 -- A Neuronal Model of a Global Workspace in Effortful Cognitive Tasks. By -- STANISLAS DEHAENE, MICHEL KERSZBERG, AND JEAN-PIERRE -- CHANGEUX152 -- Consciousness and the Brain: The Thalamocortical Dialogue in Health and -- Disease. By RODOLFO LLINAS AND URS RIBARY166 -- The Neuroanatomy of Phenomenal Vision: A Psychological Perspective. -- ByPETRA STOERIG176 -- Co-evolution of Human Consciousness and Language. By MICHAEL A. ARBIB 195 -- From Computing with Numbers to Computing with Words-From -- Manipulation of Measurements to Manipulations of Perceptions. -- By LOTFI A. ZADEH221 -- Part IV. Closing Remarks -- Who Was Cajal? By ALBERTO PORTERA-SANCHEZ253 -- Index of Contributors259 -- Subject Index261. (shrink)

This two-volume collection of cutting edge thinking about science and religion shows how scientific and religious practices of inquiry can be viewed as logically compatible, complementary, and mutually supportive. Features submissions by world-leading scientists and philosophers Discusses a wide range of hotly debated issues, including Big Bang cosmology, evolution, intelligent design, dinosaurs and creation, general and special theories of relativity, dark energy, the Multiverse Hypothesis, and Super String Theory Includes articles on stem cell research and Bioethics by William Hurlbut, who (...) served on President Bush's Bioethics Committee. (shrink)