Results for 'Toni Wright'

953 found
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  1.  15
    The structural puzzle of how serpin serine proteinase inhibitors work.H. Tonie Wright - 1996 - Bioessays 18 (6):453-464.
    Serine proteinase cleavage of proteins is essential to a wide variety of biological processes and is primarily regulated by protein inhibitors. Many inhibitors are conformationally rigid simulations of optimal serine proteinase substrates, which makes them highly efficient competitive inhibitors of target proteinases. In contrast, members of the serpin family of serine proteinase inhibitors display extensive flexibility and polymorphism, particularly in their reactive site segments and in β‐sheet secondary structure, which can take up and expel strands. Reactive site and β‐sheet polymorphism (...)
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  2.  15
    A Reader in International Relations and Political Theory.Howard Williams, Moorhead Wright & Tony Evans (eds.) - 1993 - UBC Press.
    This reader has been assembled in response to increasing dissatisfaction among a growing number of international relations scholars with the currently dominant theory of realism as well as in recognition of the large number of newly independent states which are having to write new constitutions and develop foreign relations. The book includes excerpts and essays from political theory and international relations which provide a starting point for further study of these subjects. It draws together writings representing two distinct traditions and (...)
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  3.  21
    Health Inequalities and Ethnic Vulnerabilities During COVID-19 in the UK: A Reflection on the PHE Reports.Clare Keys, Gowri Nanayakkara, Chisa Onyejekwe, Rajeeb Kumar Sah & Toni Wright - 2021 - Feminist Legal Studies 29 (1):107-118.
    COVID-19 has uncovered the vulnerabilities, inequalities and fragility present within our social community which has exposed and exacerbated the pre-existing racial and socioeconomic inequalities that disproportionately affect health outcomes for Black, Asian and Minority Ethnic (BAME) people. Such disparities are fuelled by complex socioeconomic health determinants and longstanding structural inequalities. This paper aims to explore the inequalities and vulnerabilities of BAME communities laid bare by the Public Health England (PHE) reports published in June 2020, concluding with suggested strategies to address (...)
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  4. World and Subject: Themes from McDowell.Tony Cheng - 2008 - Dissertation, National Chengchi University, Taiwan
    This essay is an inquiry into John McDowell’s thinking on ‘subjectivity.’ The project consists in two parts. On the one hand, I will discuss how McDowell understands and responds to the various issues he is tackling; on the other, I will approach relevant issues concerning subjectivity by considering different aspects of it: a subject as a perceiver, knower, thinker, speaker, agent, person and (self-) conscious being in the world. The inquiry begins by identifying and resolving a tension generated by the (...)
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  5. A Plea for the Plurality of Function.Tony Cheng - 2016 - Review of Contemporary Philosophy 15:70-81.
    In this paper I defend a pluralistic approach in understanding function, both in biological and other contexts. Talks about function are ubiquitous and crucial in biology, and it might be the key to bridge the “manifest image” and the “scientific image” identified by Sellars (1962). However, analysis of function has proven to be extremely difficult. The major puzzle is to make sense of “time-reversed causality”: how can property P be the cause of its realizer R? For example, “pumping blood” is (...)
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  6. Practice (2004). Andrew Gamble is Professor of Politics at the University of Sheffield, and a fellow of the British Academy and the Academy of Social Sciences. Among his numerous publications are Restating the State (co-edited with Tony Wright, 2004), Between Europe and Amer. [REVIEW]Nigel Gibson & Michael Jackson - forthcoming - Theoria.
     
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  7.  9
    Return to the brain of Eden: restoring the connection between neurochemistry and consciousness.Graham Gynn - 2014 - Rochester, Vermont: Inner Traditions. Edited by Tony Wright.
    An exploration of our fall from the pinnacle of human evolution 200,000 years ago and how we can begin our return. Explores recent neurological and psychological research on the brain and the role of plant biochemistry in human brain expansion. Explains how humanity's prehistoric diet change led to a neurodegenerative condition characterized by aggression and a fearful perception of the world. Outlines a strategy of raw foods, tantric sexuality, shamanic practices, and entheogens to reverse our mental degeneration and restore our (...)
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  8.  18
    A generalised framework for dispute derivations in assumption-based argumentation.Francesca Toni - 2013 - Artificial Intelligence 195 (C):1-43.
  9.  9
    Before and after Dung: Argumentation in AI and Law.Francesca Toni - 2020 - Argument and Computation 11 (1-2):221-238.
    Dung’s abstract argumentation frameworks have had a very significant role in the rise in interest in argumentation throughout this century. In this paper we will explore the impact of this seminal idea on a specific application domain, AI and Law. Argumentation is central to legal reasoning and there had been a considerable amount of work on it in AI and Law before Dung’s paper. It had, however, been rather fragmented. We argue that the abstract argumentation frameworks had a unifying effect (...)
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  10. Kant and Frege on existence.Toni Kannisto - 2018 - Synthese (8):01-26.
    According to what Jonathan Bennett calls the Kant–Frege view of existence, Frege gave solid logical foundations to Kant’s claim that existence is not a real predicate. In this article I will challenge Bennett’s claim by arguing that although Kant and Frege agree on what existence is not, they agree neither on what it is nor on the importance and justification of existential propositions. I identify three main differences: first, whereas for Frege existence is a property of a concept, for Kant (...)
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  11. Institutional versus moral obligations.Toni Vogel Carey - 1977 - Journal of Philosophy 74 (10):587-589.
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  12.  15
    Investigating subclasses of abstract dialectical frameworks.Francesca Toni - 2020 - Argument and Computation 11 (1-2):191-219.
    dialectical frameworks (ADFs) are generalizations of Dung argumentation frameworks where arbitrary relationships among arguments can be formalized. This additional expressibility comes with the price of higher computational complexity, thus an understanding of potentially easier subclasses is essential. Compared to Dung argumentation frameworks, where several subclasses such as acyclic and symmetric frameworks are well understood, there has been no in-depth analysis for ADFs in such direction yet (with the notable exception of bipolar ADFs). In this work, we introduce certain subclasses of (...)
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  13.  34
    How to confuse commitment with obligation.Toni Vogel Carey - 1975 - Journal of Philosophy 72 (10):276-284.
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  14.  12
    Logical theories and abstract argumentation: A survey of existing works.Francesca Toni - 2020 - Argument and Computation 11 (1-2):41-102.
    In 1995, in his seminal paper introducing the abstract argumentation framework, Dung has also established the first relationship between this framework and a logical framework (in this case: logic programming). Since that time, a lot of work have pursued this path, proposing different definitions, uses and exhibiting distinct relationships between argumentation and logic. In this paper, we present a survey of existing works about this topic and more especially those that address the following question: “How logic has been used for (...)
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  15. Mothers' speech adjustments: The contribution of selected child listener variables.Toni G. Cross - 1977 - In Catherine E. Snow & Charles A. Ferguson, Talking to Children: Language Input and Acquisition. Cambridge University Press. pp. 151--188.
     
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  16.  49
    The Black Atlantic: Modernity and Double Consciousness.Paul Gilroy - 1993 - Harvard University Press.
    Afrocentrism. Eurocentrism. Caribbean Studies. British Studies. To the forces of cultural nationalism hunkered down in their camps, this bold hook sounds a liberating call. There is, Paul Gilroy tells us, a culture that is not specifically African, American, Caribbean, or British, but all of these at once, a black Atlantic culture whose themes and techniques transcend ethnicity and nationality to produce something new and, until now, unremarked. Challenging the practices and assumptions of cultural studies, The Black Atlantic also complicates and (...)
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  17. The reason's proper study: essays towards a neo-Fregean philosophy of mathematics.Crispin Wright & Bob Hale - 2001 - Oxford: Clarendon Press. Edited by Crispin Wright.
    Here, Bob Hale and Crispin Wright assemble the key writings that lead to their distinctive neo-Fregean approach to the philosophy of mathematics. In addition to fourteen previously published papers, the volume features a new paper on the Julius Caesar problem; a substantial new introduction mapping out the program and the contributions made to it by the various papers; a section explaining which issues most require further attention; and bibliographies of references and further useful sources. It will be recognized as (...)
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  18. Truth and objectivity.Crispin Wright - 1992 - Cambridge: Harvard University Press.
    Recasting important questions about truth and objectivity in new and helpful terms, his book will become a focus in the contemporary debates over realism, and ...
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  19.  41
    An Emerging Group of Membrane Property Sensors Controls the Physical State of Organellar Membranes to Maintain Their Identity.Toni Radanović, John Reinhard, Stephanie Ballweg, Kristina Pesek & Robert Ernst - 2018 - Bioessays 40 (5):1700250.
    The biological membranes of eukaryotic cells harbor sensitive surveillance systems to establish, sense, and maintain characteristic physicochemical properties that ultimately define organelle identity. They are fundamentally important for membrane homeostasis and play active roles in cellular signaling, protein sorting, and the formation of vesicular carriers. Here, we compare the molecular mechanisms of Mga2 and Ire1, two sensors involved in the regulation of fatty acid desaturation and the response to unfolded proteins and lipid bilayer stress in order to identify their commonalities (...)
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  20.  37
    Conscientious Objection and Clinical Judgement: The Right to Refuse to Harm.Toni C. Saad - 2019 - The New Bioethics 25 (3):248-261.
    This paper argues that healthcare aims at the good of health, that this pursuit of the good necessitates conscience, and that conscience is required in every practical judgement, including clinical...
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  21. Hormone replacement therapy: informed consent without assessment?Toni C. Saad, Bruce Philip Blackshaw & Daniel Rodger - 2019 - Journal of Medical Ethics 45 (12):1-2.
    Florence Ashley has argued that requiring patients with gender dysphoria to undergo an assessment and referral from a mental health professional before undergoing hormone replacement therapy (HRT) is unethical and may represent an unconscious hostility towards transgender people. We respond, first, by showing that Ashley has conflated the self-reporting of symptoms with self-diagnosis, and that this is not consistent with the standard model of informed consent to medical treatment. Second, we note that the model of informed consent involved in cosmetic (...)
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  22.  42
    Mistakes and missed opportunities regarding cosmetic surgery and conscientious objection.Toni C. Saad - 2018 - Journal of Medical Ethics 44 (9):649-650.
    In her paper ‘Cosmetic surgery and conscientious objection’, Minerva rightly identifies cosmetic surgery as an interesting test case for the question of conscientious objection in medicine. Her treatment of this important subject, however, seems problematic. It is argued that Minerva's suggestion that a doctor has a prima facie duty to satisfy patient preferences even against his better clinical judgment, which we call Patient Preference Absolutism, must be regarded with scepticism. This is because it overlooks an important distinction regarding autonomy's meaning (...)
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  23.  44
    What did Adam Smith learn from François Quesnay?Toni Vogel Carey - 2020 - Journal of Scottish Philosophy 18 (2):175-191.
    Book IV of Adam Smith's Wealth of Nations concerns two rival economic theories, Mercantilism and Physiocracy. The latter, François Quesnay's system, occupies only the ninth and final chapter, and it begins with a stunning dismissal. Yet, fifteen pages later, Smith praises this theory to the skies. That cries out for explanation. Like Mercantilism, Smith's system emphasizes commerce, whereas Quesnay's is confined to agriculture. But like Physiocracy, Smith's system is built on individual liberty, whereas Mercantilism is one of government control. Despite (...)
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  24.  3
    Abstract argumentation and (optimal) stable marriage problems.Francesca Toni - 2020 - Argument and Computation 11 (1-2):15-40.
    In his pioneering work on Abstract Argumentation, P.M. Dung set a wide scenario by connecting stable models in Logic and Game Theory to simple Abstract Argumentation Frameworks ( AAF), which are essentially directed graphs in which arguments are represented as nodes, and the attack relation is represented by arrows. From such abstraction and simplicity, it is possible to capture important properties in many different fields. The Stable Marriage ( SM) problem is exactly one of such representable problems. Given two sets (...)
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  25. Le basi epistemologiche del concetto di forma nelle scienze biomediche: modelli interpretativi.Roberto Toni - 1999 - Epistemologia 22 (1):27-62.
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  26. Ontic conception and scientific explanation in biomedicine: the case of the anatomical doctrine.Roberto Toni - 2003 - Epistemologia 26 (2):285-316.
     
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  27. Topobiologv: Epistemological Implications of an Ontic Theory in Biomorphology.Roberto Toni - 2004 - Epistemologia 27 (1):83-106.
  28.  1
    The Disappearance of Ethics.Toni Saad North Bristol Nhs Trust - forthcoming - The New Bioethics:1-2.
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  29.  30
    Conscientious objection: unmasking the impartial spectator.Toni C. Saad - 2019 - Journal of Medical Ethics 45 (10):677-678.
    Hoping to bring some objectivity to the debate, Ben-Moshe has argued that conscientious objection in medicine should be accommodated based on its concordance with the ‘impartial spectator’, a metaphor for conscience drawn from the writings of Adam Smith. This response finds fault with this account on two fronts: first, that its claim to objectivity is unsubstantiated; second, that it implicitly relies on moral absolutes, despite claiming that conscience is a social construct, thereby calling its coherence and claims into question. Briefly, (...)
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  30.  4
    Similarity notions in bipolar abstract argumentation.Francesca Toni - 2020 - Argument and Computation 11 (1-2):103-149.
    The notion of similarity has been studied in many areas of Computer Science; in a general sense, this concept is defined to provide a measure of the semantic equivalence between two pieces of knowledge, expressing how “close” their meaning can be regarded. In this work, we study similarity as a tool useful to improve the representation of arguments, the interpretation of the relations between arguments, and the semantic evaluation associated with the arguments in the argumentative process. In this direction, we (...)
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  31.  33
    Leaving Productivism behind: Towards a Holistic and Processual Philosophy of Ecological Management.Pasi Heikkurinen, Toni Ruuska, Anna Kuokkanen & Sally Russell - 2021 - Philosophy of Management 20 (1):21-36.
    This article examines parallels between the increasing mental burnout and environmental overshoot in the organisational context. The article argues that there is a particular philosophy of management that connects these two phenomena of overshoot and burnout, namely productivism. As there are boundaries in all ecological processes and systems, the productivist aim of having ever more output and growth is deemed absurd. It is proposed that productivity as a management philosophy not only leads to mental ill-health in organisations but also to (...)
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  32.  31
    A Short History of British Medical Ethics.Toni Saad - 2021 - The New Bioethics 27 (4):365-368.
    This brief and remarkably inexpensive book by the distinguished Professor Maehle of Durham University is composed of five detailed studies of aspects of nineteenth and twentieth century British med...
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  33. Frege's conception of numbers as objects.Crispin Wright - 1983 - [Aberdeen]: Aberdeen University Press.
  34.  35
    Cognitive interdependence in close relationships.Daniel M. Wegner, Toni Giuliano & Paula T. Hertel - 1985 - In W. J. Ickes, Compatible and Incompatible Relationships. Springer Verlag. pp. 253--276.
  35.  19
    Metaphors at Work: Maintaining the Salience of Gender in Self-Managing Teams.Toni Calasanti & Marjukka Ollilainen - 2007 - Gender and Society 21 (1):5-27.
    Self-managing teams have been predicted to break down organizational hierarchies and sex-segregated functional divisions. Based on participant observation and interviews with 39 men and women in service-oriented self-managing teams, the authors found that the metaphor of family emerged in interviews as a popular way to describe teams' interaction and social relations. The ways that team members used the family metaphor revealed that women were often perceived in familial roles that the authors argue encourage emotional labor. Although relational tasks may not (...)
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  36. Warrant for nothing (and foundations for free)?Crispin Wright - 2004 - Aristotelian Society Supplementary Volume 78 (1):167–212.
  37.  21
    What Conflict of Duty is Not.Toni Vogel Carey - 1985 - Pacific Philosophical Quarterly 66 (1-2):204-215.
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  38. Functions.Larry Wright - 1973 - Philosophical Review 82 (2):139-168.
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  39.  46
    Eugène Bouchut’s (1818–1891) Early Anticipation of the Concept of Brain Death.Toni Saad - 2022 - Journal of Medicine and Philosophy 47 (3):407-423.
    The conventional historical account of the concept of brain death credits developments and discoveries of the twentieth century with its inception, emphasizing the role of technological developments and professional conferences, notably the 1968 Ad Hoc Committee of the Harvard Medical School to Examine the Definition of Brain Death. This essay argues that the French physician Eugène Bouchut anticipated the concept of brain death as early as 1846. Correspondence with Bouchut’s understanding of brain death and one important contemporary concept of brain (...)
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  40.  14
    Abschiedlich leben! Ein Plädoyer.Toni Tholen - 2024 - Allgemeine Zeitschrift für Philosophie 49 (2):237-242.
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  41.  19
    Les contours d'une Europe cosmopolite : une sémiotique politique de la globalisation.Toni Ramoneda - 2006 - Semiotica 2006 (159):329-341.
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  42. Teleological Explanations: An Etiological Analysis of Goals and Functions.Larry Wright - 1976 - University of California Press.
    INTRODUCTION The appeal to teleological principles of explanation within the body of natural science has had an unfortunate history. ...
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  43.  53
    What nursing chooses not to know: Practices of epistemic silence/silencing.Jessica Dillard-Wright, Claire Valderama-Wallace, Lucinda Canty, Amélie Perron, Ismalia De Sousa & Janice Gullick - 2023 - Nursing Philosophy 24 (3):e12443.
    Drawing from a keynote panel held at the hybrid 25th International Philosophy of Nursing Conference, this discussion paper examines the question of epistemic silence in nursing from five different perspectives. Contributors include US‐based scholar Claire Valderama‐Wallace, who meditated on ecosystems of settler colonial logics of nursing; American scholar Lucinda Canty discussed the epistemic silencing of nurses of colour; Canadian scholar Amelie Perron interrogated the use of disobedience and parrhesia in and for nursing; Canada‐based scholar Ismalia De Sousa considered what nursing (...)
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  44.  29
    Forecasting with jury-based probabilistic argumentation.Francesca Toni, Antonio Rago & Kristijonas Čyras - 2023 - Journal of Applied Non-Classical Logics 33 (3):224-243.
    1. The benefits resulting from a combination of quantitative (e.g. probabilistic) and qualitative (e.g. logic-based) reasoning are widely acknowledged (e.g. see Domingos et al., 2006; Poole, 2011)....
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  45.  75
    National Ethics Advisory Bodies in the Emerging Landscape of Responsible Research and Innovation.Franc Mali, Toni Pustovrh, Blanka Groboljsek & Christopher Coenen - 2012 - NanoEthics 6 (3):167-184.
    The article examines the role played by policy advice institutions in the governance of ethically controversial new and emerging science and technology in Europe. The empirical analysis, which aims to help close a gap in the literature, focuses on the evolution, role and functioning of national ethics advisory bodies (EABs) in Europe. EABs are expert bodies whose remit is to issue recommendations regarding ethical aspects of new and emerging science and technology. Negative experiences with the impacts of science and technology (...)
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  46.  63
    A Continuation of Paul Grobstein's Theory of Science as Story Telling and Story Revising: A Discussion of its Relevance to History.Toni Weller - 2006 - Journal of Research Practice 2 (1):Article M3.
    This paper applies Paul Grobstein's theory of science as story telling and story revising to history. The purpose of drawing such links is to show that in our current age when disciplinary borders are becoming increasingly blurred, what may be effective research practice for one discipline, may have some useful insights for another. It argues that what Grobstein advocates for science makes just as much sense for history and that historians have long recognised in their own discipline many of the (...)
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  47.  31
    Another nursing is possible: Ethics, political economies, and possibility in an uncertain world.Jess Dillard-Wright - 2024 - Nursing Philosophy 25 (3):e12484.
    Overtaxed by the realities laid bare in the pandemic, nursing has imminent decisions to make. The exigencies of pandemic times overextend a health care infrastructure already groaning under the weight of inequitable distribution of resources and care commodified for profit. We can choose to prioritise different values. Invoking philosopher of science Isbelle Stengers's manifesto for slow science, this is not the only nursing that is possible. With this paper, I pick up threads of nursing's historical ontology, drawing previous scholarship on (...)
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  48. (2 other versions)The perils of dogmatism.Crispin Wright - 2007 - In Susana Nuccetelli & Gary Seay, Themes from G. E. Moore: New Essays in Epistemology. New York: Oxford University Press.
    "Dogmatism" is a term renovated by James Pryor [2000] to stand for a certain kind of neo-Moorean response to Scepticism and an associated conception of the architecture of basic perceptual warrant. Pryor runs the response only for (some kinds of) perceptual knowledge but here I will be concerned with its general structure and potential as a possible global anti-sceptical strategy. Something like it is arguably also present in recent writings of Burge 1 and Peacocke.2 If the global strategy could succeed, (...)
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  49. Automatic evaluation of design alternatives with quantitative argumentation.Pietro Baroni, Marco Romano, Francesca Toni, Marco Aurisicchio & Giorgio Bertanza - 2015 - Argument and Computation 6 (1):24-49.
    This paper presents a novel argumentation framework to support Issue-Based Information System style debates on design alternatives, by providing an automatic quantitative evaluation of the positions put forward. It also identifies several formal properties of the proposed quantitative argumentation framework and compares it with existing non-numerical abstract argumentation formalisms. Finally, the paper describes the integration of the proposed approach within the design Visual Understanding Environment software tool along with three case studies in engineering design. The case studies show the potential (...)
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  50.  48
    The Value Gap.Toni Rønnow-Rasmussen - 2021 - Oxford: Oxford University Press.
    In The Value Gap, Toni Rønnow-Rasmussen addresses the distinction between what is finally good and what is finally good-for, two value notions that are central to ethics and practical deliberation. The first part of the book argues against views that claim that one of these notions is either faulty, or at best conceptually dependent on the other notion. Whereas these two views disagree on whether it is good or good-for that is the flawed or dependent concept, it is argued, (...)
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