It will be interesting to listen to the personal beliefs concerning “Truth” as revealed in the studies of different scholars in different countries. But how will such a collection of beliefs contribute to the seeking of truth itself when we want to attribute to the word truth one of the adjectives: “absolute,” or “universal”?

All surviving jawed vertebrate representatives achieve diversity in immunoglobulin‐based B and T cell receptors for antigen recognition through recombinatorial rearrangement of V(D)J segments. However, the extant jawless vertebrates, lampreys and hagfish, instead generate three types of variable lymphocyte receptors (VLRs) through a template‐mediated combinatorial assembly of different leucine‐rich repeat (LRR) sequences. The clonally diverse VLRB receptors are expressed by B‐like lymphocytes, while the VLRA and VLRC receptors are expressed by lymphocyte lineages that resemble αβ and γδ T lymphocytes, respectively. These (...) findings suggest that three basic types of lymphocytes, one B‐like and two T‐like, are an essential feature of vertebrate adaptive immunity. Around 500 million years ago, a common ancestor of jawed and jawless vertebrates evolved a genetic program for the development of prototypic lymphoid cells as a foundation for an adaptive immune system. This acquisition preceded the convergent evolution of alternative types of clonally diverse receptors for antigens in all vertebrates, as reviewed in this article. (shrink)

Currently in Japan, discontinuing an invasive mechanical ventilator (IMV) is illegal; therefore IMV-related decision making is a crucial issue. This study examined IMV decision-making factors and psychological conflict in 50 patients with amyotrophic lateral sclerosis. The Herth Hope Index was used for the assessment of pre- and post-IMV conflict. Interviews identified some decision-making factors: patient’s decision, patient’s and family’s mutual decision, family’s decision, and emergency-induced without patient’s or family’s consent. Participants who experienced no IMV-related regret received sufficient prior IMV education (...) from physicians and nurses, and time for reflection and family consultation. Their hope was similar to their pre-onset levels. Patients who received no prior IMV education accepted treatment as a natural progression. Their hope levels were lower than pre-onset. Those who received only a brief prior IMV explanation rejected the ventilator, experiencing regret if they were given an emergency IMV. Their hope levels were among the lowest. However, some of these patients managed to overcome their regret through being helped by nurses. Sufficient physician explanation and nursing advocacy for autonomous patient decision making are critical for improving hope in this patient group. (shrink)

This essay examines the political implications of Edo (present-day Tokyo) popular culture in early modern Japan by focusing on the interface between distinct forms of literary and visual representation and the configuration of social order (the status hierarchy and the division of labor), as well as moral and ideological discourses that were conducive to the reproduction of the order. Central to the forms of representation in Edo popular culture was the overarching literary and artistic principle, which I call a phrase (...) adapted from M.M. Bakhtin's work on Fyodor Dostoevsky. By creating a dialogical interaction of divergent voices and perspectives, Edo popular culture created pluralized, contentious images of Tokugawa society, images that underlined contradictory realities that had become widely discernible around the turn of the eighteenth century. The most salient of all the contradictions was the growing disjuncture between the ideological premise of social and economic hierarchies and their actual reversals. The dialogic imagination captured and accentuated the fluid and dynamic social interactions that threw the formal arrangements of social order into disarray, as well as the widely perceived tensions originating from these interactions, by supplying images that sharply contrasted with those that the Tokugawa authorities worked hard to foster and defend: of a harmonious, self-contained, and perfectly functioning society. (shrink)

dai 1-kan. Hō no kihon riron -- dai 2-5-kan. Hōshisō no rekishiteki tenkai -- dai 6-8-kan. Gendai jitteihō no kihon mondai.

This book aims at analyzing semantic values of proper names occurring in belief reports. The focus is on the discussion about Frege s puzzle concerning belief reports. The goal is to analyze Frege s puzzle without giving up semantic innocence. To this end, a pragmatic analysis named VarCA analysis is proposed.".

Husserl’s notion of “sense” has often been interpreted through a Fregean lens. I will show that Husserl saw it as an acquaintance with the background or horizon of perceptual objects. He understands reason (Vernunft) as prescribing rules for performance with regard to perceptual objects. Thus Husserl’s view has a wider scope of experience than Kant’s sense of it as a pre-reflective acquaintance with one’s environment. After Ideas I Husserl develops these notions as part of his theory of the intersubjective world. (...) Heidegger takes over the insights of Husserl and brings out the performative turn inherent in phenomenology by critiquing Husserl’s orientation to theoretical perceptual experience. The reference of performative expressions is not determined by the contents but by performance. What is disclosed in the phenomenological notion of sense is the background against which human existence is to be understood. (shrink)