Consent remains a crucial, yet challenging, cornerstone of clinical practice. The ethical, legal and professional understandings of this construct have evolved away from a doctor-centred act to a patient-centred process that encompasses the patient’s values, beliefs and goals. This alignment of consent with the philosophy of shared decision-making was affirmed in a recent high-profile Supreme Court ruling in England. The communication of information is central to this model of health care delivery but it can be difficult for doctors to gauge (...) the information needs of the individual patient. The aim of this paper is to describe ‘core information sets’ which are defined as a minimum set of consensus-derived information about a given procedure to be discussed with all patients. Importantly, they are intended to catalyse discussion of subjective importance to individuals. The model described in this paper applies health services research and Delphi consensus-building methods to an idea orginally proposed 30 years ago. The hypothesis is that, first, large amounts of potentially-important information are distilled down to discrete information domains. These are then, secondly, rated by key stakeholders in multiple iterations, so that core information of agreed importance can be defined. We argue that this scientific approach is key to identifying information important to all stakeholders, which may otherwise be communicated poorly or omitted from discussions entirely. Our methods apply systematic review, qualitative, survey and consensus-building techniques to define this ‘core information’. We propose that such information addresses the ‘reasonable patient’ standard for information disclosure but, more importantly, can serve as a spring board for high-value discussion of importance to the individual patient. The application of established research methods can define information of core importance to informed consent. Further work will establish how best to incorporate this model in routine practice. (shrink)

The subject of this book is epistemology. Epistemology is the theory of knowledge, the study of the nature, sources, and limitations of knowledge and justification. In studying the nature of knowledge and justification, theorists typically try to delineate the conditions that must be met for a given person to know, or justifiably believe, that a given proposition is true. That is, they offer analyses of knowledge and justification. In this introduction, we will briefly describe the task of analysis, and review (...) some of the ways people have understood epistemic concepts. We will also outline some of the difficulties theorists have confronted while working out what may be known. (shrink)

Moving beyond the work of Rawls and his critics, this concise collection contains critical essays in contemporary political philosophy. All have been chosen for their importance and accessibility, and some have been edited by their authors for inclusion in this work. Political Philosophy in the Twenty-First Century covers five main topics: equality, justice, liberty, democracy, and human rights. To assist readers, the editors have also provided section introduction and study questions as well as an overall introduction explaining the background (...) to contemporary work in political philosophy. Beginning where most other anthologies in political philosophy conclude, this book can be used alone or in conjunction with any collection of historical sources. (shrink)

"[Of] the 12 well-crafted essays in this volume...the most useful are those dealing with the Holocaust." —Choice "Especially recommended for college-level students of Jewish history and culture." —The Bookwatch This is a critical exploration of the most repercussive topics in modern Jewish history and thought. A sequel to Katz's National Jewish Book Award-winning study, Post-Holocaust Dialogues, this book identifies the main issues in the contemporary Jewish intellectual universe and outlines a larger, more synthetic understanding of contemporary Jewish existence.

Are liberalism and perfectionism compatible? In this study Steven Wall presents and defends a perfectionist account of political morality that takes issue with many currently fashionable liberal ideas but retains the strong liberal commitment to the ideal of personal autonomy. He begins by critically discussing the most influential version of anti-perfectionist liberalism, examining the main arguments that have been offered in its defence. He then clarifies the ideal of personal autonomy, presents an account of its value and shows (...) that a strong commitment to personal autonomy is fully compatible with an endorsement of perfectionist political action designed to promote valuable pursuits and discourage base ones. (shrink)

The burden of the present essay is to argue in favor of a proposition which is obviously true: that hypothesis choice in science is largely a rational procedure. This proposition needs arguing for because there is no philosophical theory, generally accepted as adequate, which explains why science is, or explains how science can be, rational. The main obstacles to an acceptable philosophical theory on this matter are the problems of induction . These problems seem to tell us that no (...) amount of evidence can in any way raise the probability or increase the rational believability of any hypothesis not implied by the evidence. The approach taken here is to give up on solving the problems of induction and to attempt to explain scientific rationality on some other basis. There are three main elements of this theory: rational hypothesis choice is explicated as rational acceptance of hypotheses, rather than belief; pragmatic criteria are employed to limit--always tentatively--the hypotheses under consideration; choice among hypotheses is to be made in accordance with rules that have the following property: if the true hypothesis is under consideration, then the probability of choosing the true hypothesis is greater than 0.5. Such rules correspond to what are called hypothesis testing situations in statistics. The theory is illustrated and developed through a number of examples. (shrink)

In this paper I argue, contrary to the traditional interpretation, that dividing Wittgenstein's career into “The Early Wittgenstein” and “The Later Wittgenstein” is a serious distortion. The main task of the paper is to outline a reading of the Tractatus that will give us one Wittgenstein. Building on the work of James Conant, Cora Diamond, Juliet Floyd, Warren Goldfarb, John McDowell, and Hilary Putnam, I will argue that throughout his career, Wittgenstein argued against metaphysical realism. I offer a reading (...) of the Tractatus which is a retelling of the history of early analytic ontology. (shrink)

‘Down Freedom’s Main Line’ Two waves of democratization define the post-Cold War era of globalization. The first one saw democracies emerge in post-communist countries and post-Apartheid South Africa. The current wave began with the uprisings in the Middle East. The first focused on the formal institutions of the market and the liberal state, the second is participatory and rooted in collective action. The individualistic conception of freedom and democracy that underlies the first wave is false and fetishistic. The second (...) wave shows democracy’s moral appeal is the commitment to equal participation in determining the terms and conditions of social life. Freedom, thus, requires collective action under conditions of equality, mutual recognition, and respect. (shrink)

In a recent book, Asymmetries in Time, Paul Horwich presents a systematic account of various temporal asymmetries, including a neo-Reichenbachian account of the (apparent) fact that we know more about the past than the future, the epistemological time asymmetry. I find some obscurities in Horwich's presentation, however, and I argue that when his view is understood in a way that I shall propose, it does represent an advance on Reichenbach's, but it fails to vindicate Horwich's "main point...that our special (...) knowledge of the past derives from the fork asymmetry. (shrink)

This monograph reappraises the role of Bertrand Russell's philosophical works in establishing the analytical tradition in philosophy. It's main aims are to: * improve our understanding of the history of analytical philosophy * engage in the important disputes surrounding the interpretation of Russell's philosophy * make a contribution to central issues in current analytical philosophy. Drawing extensively from Russell's less well known and unpublished works, this book is a welcome addition to the literature and will undoubtedly find a place (...) on the bookshelves of philosophers around the world. (shrink)

The past few years has seen a resurgence in the public interest in space flight and travel. Spurred mainly by the likes of technology billionaires like Elon Musk and Jeff Bezos, the topic poses both unique scientific as well as ethical challenges. This paper looks at the concept of generation ships, conceptual behemoth ships whose goal is to bring a group of human settlers to distant exoplanets. These ships are designed to host multiple generations of people who will be born, (...) live, and die on these ships long before it reaches its destination. This paper takes reproductive ethics as its lens to look at how genetic enhancement interventions can and should be used not only to ensure that future generations of offspring on the ships, and eventual exoplanet colonies, live a minimally good life but that their births are contingent on them living genuinely good and fulfilling lives. The paper makes the further claim that if such a thesis holds, it also does so for human enhancement on Earth. (shrink)

Kaci Hickox was a nurse who worked with persons who were infected with Ebola in West Africa. When she returned to the United States, the governors of New Jersey and Maine intervened to confine her to inpatient quarantine despite the fact that she was asymptomatic and had no serological evidence of infection. She defied the quarantine which resulted in enormous public attention and discussion of quarantine and public fear. This article summarizes the case discussing the history of the case, the (...) government actions, and the final legal rulings. (shrink)

My dissertation has two main parts. In the first half, I draw out an underlying presupposition of Descartes' philosophy: what I term "atomism of thought." Descartes employs a radical procedure of doubt in order to show that the first principle of his philosophy, the cogito, is an unshakeable foundation of knowledge. In the dialogue that follows his dissemination of the Meditations, Descartes reveals that a whole set of concepts and rational principles innate in our minds are never doubted. These (...) fundamental units of thought are indivisible, distinct, and isolated, and enable the possibility of any rational demonstration. Atoms of thought are perfectly individuated because God has created them as such. Likewise, our minds have been fashioned such that we necessarily have a clear and distinct perception every time we alight upon these simple notions. In the second part of the dissertation, I take up critiques of Descartes' view given by Nietzsche and Heidegger. In the chapter on Nietzsche, I attempt to fill a lacuna in scholarship about Nietzsche's commentary on Descartes. More specifically, I argue that once the foundation of God is displaced, the basis for accepting atomism of thought dissolves. In the final chapter, I analyze Heidegger's critique of Cartesian atomism. I first look at Heidegger's critique of classical truth as correspondence from Being and Time, and show how it is relevant to a critique of atomism. Then I show how the early Heidegger's holistic philosophical framework can provide an alternative that avoids the pitfalls of atomism. While I limit the scope of my analysis to Descartes' particular formulation, atomism of thought was an influential doctrine throughout modern philosophy. This aspect of Cartesianism has persisted and continues to be a significant theoretical underpinning of many contemporary views. It is my contention that Nietzsche and Heidegger have important contributions to make to this area of thought, and the relative neglect of their work in recent scholarship is a detrimental oversight. (shrink)

Standard philosophical explanations of the concept of knowledge invoke a personal goal of having true beliefs, and explain the other requirements for knowledge as indicating the best way to achieve that goal. In this highly original book, Steven L. Reynolds argues instead that the concept of knowledge functions to express a naturally developing kind of social control, a complex social norm, and that the main purpose of our practice of saying and thinking that people 'know' is to improve (...) our system for exchanging information, which is testimony. He makes illuminating comparisons of the knowledge norm of testimony with other complex social norms - such as those requiring proper clothing, respectful conversation, and the complementary virtues of tact and frankness - and shows how this account fits with our concept of knowledge as studied in recent analytic epistemology. His book will interest a range of readers in epistemology, psychology, and sociology. (shrink)

This paper examines the interplay of changelessness and change, being and becoming, from an historical and dialectical standpoint. Topological paradox is employed to elucidate the dynamic interweaving of these ontological opposites. The essay concludes by exploring the relevance of the dialectic to the question of human freedom.

This paper investigates the process of reasoning through which a judge determines whether a precedent-case gives her a binding reason to follow in her present-case. I review the objections that have been raised against the two main accounts of reasoning by precedent: the rule-account and the analogy-account. I argue that both accounts can be made viable by amending them to meet the objections. Nonetheless, I believe that there is an argument for preferring accounts that integrate analogical reasoning: any account (...) of reasoning by precedent that is descriptively minimally adequate will leave some room for judicial discretion. Discretion should be used under consideration of the best legally relevant arguments for and against a decision. Integrating analogical reasoning helps the judge to bring to her own attention the strongest case for following. Analogical reasoning also eases the recognition of possible reasons for distinguishing. Thereby, it facilitates a more balanced decision-making process. (shrink)

The present paper offers an analogical support for the use of rational intuition, namely, if we regard sense perception as a mental faculty that (in general) delivers justified beliefs, then we should treat intuition in the same manner. I will argue that both the cognitive marks of intuition and the role it traditionally plays in epistemology are strongly analogous to that of perception, and barring specific arguments to the contrary, we should treat rational intuition as a source of prima facie (...) justified beliefs. There are two main arguments against the intuition-perception analogy that I will consider and find lacking. First is that while we do use perceptions as evidence to believe certain propositions, in fact no one ever does use intuition evidentially. The second argument, stemming from experimental philosophy, grants that philosophers do use intuitions evidentially, but this practice is fatally unlike that of perception, in that perception yields warranted beliefs and intuition does not. (shrink)

ABSTRACT I argue that this examination and appreciation for the shift to abductive reasoning should be extended to the intersection of neuroscience and novel brain-computer interfaces too. This paper highlights the implications of applying abductive reasoning to personalized implantable neurotechnologies. Then, it explores whether abductive reasoning is sufficient to justify insurance coverage for devices absent widespread clinical trials, which are better applied to one-size-fits-all treatments. INTRODUCTION In contrast to the classic model of randomized-control trials, often with a large number of (...) subjects enrolled, precision medicine attempts to optimize therapeutic outcomes by focusing on the individual.[i] A recent publication highlights the strengths and weakness of both traditional evidence-based medicine and precision medicine.[ii] Plus, it outlines a tension in the shift from evidence-based medicine’s inductive reasoning style (the collection of data to postulate general theories) to precision medicine’s abductive reasoning style (the generation of an idea from the limited data available).[iii] The paper’s main example is the application of precision medicine for the treatment of cancer.[iv] I argue that this examination and appreciation for the shift to abductive reasoning should be extended to the intersection of neuroscience and novel brain-computer interfaces too. As the name suggests, brain-computer interfaces are a significant advancement in neurotechnology that directly connects someone’s brain to external or implanted devices.[v] Among the various kinds of brain-computer interfaces, adaptive deep brain stimulation devices require numerous personalized adjustments to their settings during the implantation and computation stages in order to provide adequate relief to patients with treatment-resistant disorders. What makes these devices unique is how adaptive deep brain stimulation integrates a sensory component to initiate the stimulation. While not commonly at the level of sophistication as self-supervising or generative large language models,[vi] they currently allow for a semi-autonomous form of neuromodulation. This paper highlights the implications of applying abductive reasoning to personalized implantable neurotechnologies. Then, it explores whether abductive reasoning is sufficient to justify insurance coverage for devices absent widespread clinical trials, which are better applied to one-size-fits-all treatments.[vii] ANALYSIS I. The State of Precision Medicine in Oncology and the Epistemological Shift While a thorough overview of precision medicine for the treatment of cancer is beyond the scope of this article, its practice can be roughly summarized as identifying clinically significant characteristics a patient possesses (e.g., genetic traits) to land on a specialized treatment option that, theoretically, should benefit the patient the most.[viii] However, in such a practice of stratification patients fall into smaller and smaller populations and the quality of evidence that can be applied to anyone outside these decreases in turn.[ix] As inductive logic helps to articulate, the greater the number of patients that respond to a particular therapy the higher the probability of its efficacy. By straying from this logical framework, precision medicine opens the treatment of cancer to more uncertainty about the validity of these approaches to the resulting disease subcategories.[x] Thus, while contemporary medical practices explicitly describe some treatments as “personalized”, they ought not be viewed as inherently better founded than other therapies.[xi] A relevant contemporary case of precision medicine out of Norway focuses on the care of a patient with cancer between the ventricles of the heart and esophagus, which had failed to respond to the standard regimen of therapies over four years.[xii] In a last-ditch effort, the patient elected to pay out-of-pocket for an experimental immunotherapy (nivolumab) at a private hospital. He experienced marked improvements and a reduction in the size of the tumor. Understandably, the patient tried to pursue further rounds of nivolumab at a public hospital. However, the hospital initially declined to pay for it given the “lack of evidence from randomised clinical trials for this drug relating to this [patient’s] condition.”[xiii] In rebuttal to this claim, the patient countered that he was actually similar to a subpopulation of patients who responded in “open‐label, single arm, phase 2 studies on another immune therapy drug” (pembrolizumab).[xiv] Given this interpretation of the prior studies and the patient’s response, further rounds of nivolumab were approved. Had the patient not had improvements in the tumor’s size following a round of nivolumab, then pembrolizumab’s prior empirical evidence in isolation would have been insufficient, inductively speaking, to justify his continued use of nivolumab.[xv] The case demonstrates a shift in reasoning from the traditional induction to abduction. The phenomenon of ‘cancer improvement’ is considered causally linked to nivolumab and its underlying physiological mechanisms.[xvi] However, “the weakness of abductions is that there may always be some other better, unknown explanation for an effect. The patient may for example belong to a special subgroup that spontaneously improves, or the change may be a placebo effect. This does not mean, however, that abductive inferences cannot be strong or reasonable, in the sense that they can make a conclusion probable.”[xvii] To demonstrate the limitations of relying on the abductive standard in isolation, commentators have pointed out that side effects in precision medicine are hard to rule out as being related to the initial intervention itself unless trends from a group of patients are taken into consideration.[xviii] As artificial intelligence (AI) assists the development of precision medicine for oncology, this uncertainty ought to be taken into consideration. The implementation of AI has been crucial to the development of precision medicine by providing a way to combine large patient datasets or a single patient with a large number of unique variables with machine learning to recommend matches based on statistics and probability of success upon which practitioners can base medical recommendations.[xix] The AI is usually not establishing a causal relationship[xx] – it is predicting. So, as AI bleeds into medical devices, like brain-computer interfaces, the same cautions about using abductive reasoning alone should be carried over. II. Responsive Neurostimulation, AI, and Personalized Medicine Like precision medicine in cancer treatment, computer-brain interface technology similarly focuses on the individual patient through personalized settings. In order to properly expose the intersection of AI, precision medicine, abductive reasoning, and implantable neurotechnologies, the descriptions of adaptive deep brain stimulation systems need to deepen.[xxi] As a broad summary of adaptive deep brain stimulation, to provide a patient with the therapeutic stimulation, a neural signal, typically referred to as a local field potential,[xxii] must first be detected and then interpreted by the device. The main adaptive deep brain stimulation device with premarket approval, the NeuroPace Responsive Neurostimulation system, is used to treat epilepsy by detecting and storing “programmer-defined phenomena.”[xxiii] Providers can optimize the detection settings of the device to align with the patient’s unique electrographic seizures as well as personalize the reacting stimulation’s parameters.[xxiv] The provider adjusts the technology based on trial and error. One day machine learning algorithms will be able to regularly aid this process in myriad ways, such as by identifying the specific stimulation settings a patient may respond to ahead of time based on their electrophysiological signatures.[xxv] Either way, with AI or programmers, adaptive neurostimulation technologies are individualized and therefore operate in line with precision medicine rather than standard treatments based on large clinical trials. Contemporary neurostimulation devices are not usually sophisticated enough to be prominent in AI discussions where the topics of neural networks, deep learning, generative models, and self-attention dominate the conversation. However, implantable high-density electrocorticography arrays (a much more sensitive version than adaptive deep brain stimulation systems use) have been used in combination with neural networks to help patients with neurologic deficits from a prior stroke “speak” through a virtual avatar.[xxvi] In some experimental situations, algorithms are optimizing stimulation parameters with increasing levels of independence.[xxvii] An example of neurostimulation that is analogous to the use of nivolumab in Norway surrounds a patient in the United States who was experiencing both treatment-resistant OCD and temporal lobe epilepsy.[xxviii]Given the refractory nature of her epilepsy, implantation of an adaptive deep brain stimulation system was indicated. As a form of experimental therapy, her treatment-resistant OCD was also indicated for the off-label use of an adaptive deep brain stimulation set-up. Another deep brain stimulation lead, other than the one implanted for epilepsy, was placed in the patient’s right nucleus accumbens and ventral pallidum region given the correlation these nuclei had with OCD symptoms in prior research. Following this, the patient underwent “1) ambulatory, patient-initiated magnet-swipe storage of data during moments of obsessive thoughts; (2) lab-based, naturalistic provocation of OCD-related distress (naturalistic provocation task); and (3) lab-based, VR [virtual reality] provocation of OCD-related distress (VR provocation task).”[xxix] Such signals were used to identify when to deliver the therapeutic stimulation in order to counter the OCD symptoms. Thankfully, following the procedure and calibration the patient exhibited marked improvements in their OCD symptoms and recently shared her results publicly.[xxx] In both cases, there is a similar level of abductive justification for the efficacy of the delivered therapy. In the case study in which the patient was treated with adaptive deep brain stimulation, they at least had their neural activity tested in various settings to determine the optimum parameters for treatment to avoid them being based on guesswork. Additionally, the adaptive deep brain stimulation lead was already placed before the calibration trials were conducted, meaning that the patient had already taken on the bulk of the procedural risk before the efficacy could be determined. Such an efficacy test could have been replicated in the first patient’s cancer treatment, had it been biopsied and tested against the remaining immunotherapies in vitro. Yet, in the case of cancer with few options, one previous dose of a drug that appeared to work on the patient may justify further doses. However, as the Norwegian case presents, corroboration with known responses to a similar drug (from a clinical trial) could be helpful to validate the treatment strategy. (It should be noted that both patients were resigned to these last resort options regardless of the efficacy of treatment.) There are some elements of inductive logic seen with adaptive deep brain stimulation research in general. For example, abductively the focus could be that patient X’s stimulation parameters are different from patient Y’s and patient Z’s. In contrast, when grouped as subjects who obtained personalized stimulation, patients X, Y, and Z demonstrate an inductive aspect to this approach’s safety and/or efficacy. The OCD case holds plenty of abductive characteristics in line with precision medicine’s approach to treating cancer and as more individuals try the method, there will be additional data. With the gradual integration of AI into brain-computer interfaces in the name of efficacy, this reliance on abduction will continue, if not grow, over time. Moving forward, if a responsive deep brain stimulation treatment is novel and individualized (like the dose of nivolumab) and there is some other suggestion of efficacy (like clinical similarities to other patients in the literature), then it may justify insurance coverage for the investigative intervention, absent other unrelated reasons to deny it. III. Ethical Implications and Next Steps While AI’s use in oncology and neurology is not yet as prominent as its use in other fields (e.g., radiology), it appears to be on the horizon for both.[xxxi] AI can be found in both the functioning of the neurotechnologies as well as the implementation of precision medicine. The increasing use of AI may serve to further individualize both oncologic and neurological therapies. Given these implications and the handful of publications cited in this article, it is important to have a nuanced evaluation of how these treatments, which heavily rely on abductive justification, ought to be managed. The just use an abductive approach may be difficult as AI infused precision medicine is further pursued. At baseline, such technology relies on a level of advanced technology literacy among the general public and could exclude populations who lack access to basic technological infrastructure or know-how from participation.[xxxii] Even among nations with adequate infrastructure, as more patients seek out implantable neurotechnologies, which require robust healthcare resources, the market will favor patient populations that can afford this complex care.[xxxiii] If patients already have the means to pay for an initial dose/use of a precision medicine product out of pocket, should insurance providers be required to cover subsequent treatments?[xxxiv] That is, if a first dose of a cancer drug or a deep brain stimulator over its initial battery life is successful, patients may feel justified in having the costs of further treatments covered. The Norwegian patient’s experience implies there is a precedent for the idea that some public insurance companies ought to cover successful cancer therapies, however, insurance companies may not all see themselves as obligated to cover neurotechnologies that rely on personalized settings or that are based on precision/abductive research more than on clinical trials. CONCLUSION The fact that the cases outlined above rely on abductive style of reasoning implies that there may not be as strong a justification for coverage by insurance, as they are both experimental and individualized, when compared to the more traditional large clinical trials in which groups have the same or a standardized protocol (settings/doses). If a study is examining the efficacy of a treatment with a large cohort of patients or with different experimental groups/phases, insurance companies may conclude that the resulting symptom improvements are more likely to be coming from the devices themselves. A preference for inductive justification may take priority when ruling in favor of funding someone’s continued use of an implantable neurostimulator. There are further nuances to this discussion surrounding the classifications of these interventions as research versus clinical care that warrant future exploration, since such a distinction is more of a scale[xxxv] than binary and could have significant impacts on the “right-to-try” approach to experimental therapies in the United States.[xxxvi] Namely, given the inherent limitations of conducting large cohort trials for deep brain stimulation interventions on patients with neuropsychiatric disorders, surgically innovative frameworks that blend abductive and inductive methodologies, like with sham stimulation phases, have traditionally been used.[xxxvii] Similarly, for adaptive brain-computer interface systems, if there are no large clinical trials and instead only publications that demonstrate that something similar worked for someone else, then, in addition to the evidence that the first treatment/dose worked for the patient in question, the balance of reasoning would be valid and arguably justify insurance coverage. As precision approaches to neurotechnology become more common, frameworks for evaluating efficacy will be crucial both for insurance coverage and for clinical decision making. ACKNOWLEDGEMENT This article was originally written as an assignment for Dr. Francis Shen’s “Bioethics & AI” course at Harvard’s Center for Bioethics. I would like to thank Dr. Shen for his comments as well as my colleagues in the Lázaro-Muñoz Lab for their feedback. - [i] Jonathan Kimmelman and Ian Tannock, “The Paradox of Precision Medicine,” Nature Reviews. Clinical Oncology 15, no. 6 (June 2018): 341–42, https://doi.org/10.1038/s41571-018-0016-0. [ii] Henrik Vogt and Bjørn Hofmann, “How Precision Medicine Changes Medical Epistemology: A Formative Case from Norway,” Journal of Evaluation in Clinical Practice 28, no. 6 (December 2022): 1205–12, https://doi.org/10.1111/jep.13649. [iii] David Barrett and Ahtisham Younas, “Induction, Deduction and Abduction,” Evidence-Based Nursing 27, no. 1 (January 1, 2024): 6–7, https://doi.org/10.1136/ebnurs-2023-103873. [iv] Vogt and Hofmann, “How Precision Medicine Changes Medical Epistemology,” 1208. [v] Wireko Andrew Awuah et al., “Bridging Minds and Machines: The Recent Advances of Brain-Computer Interfaces in Neurological and Neurosurgical Applications,” World Neurosurgery, May 22, 2024, S1878-8750(24)00867-2, https://doi.org/10.1016/j.wneu.2024.05.104. [vi] Mark Riedl, “A Very Gentle Introduction to Large Language Models without the Hype,” Medium (blog), May 25, 2023, https://mark-riedl.medium.com/a-very-gentle-introduction-to-large-language-models-without-the-hype-5 f67941fa59e. [vii] David E. Burdette and Barbara E. Swartz, “Chapter 4 - Responsive Neurostimulation,” in Neurostimulation for Epilepsy, ed. Vikram R. Rao (Academic Press, 2023), 97–132, https://doi.org/10.1016/B978-0-323-91702-5.00002-5. [viii] Kimmelman and Tannock, 2018. [ix] Kimmelman and Tannock, 2018. [x] Simon Lohse, “Mapping Uncertainty in Precision Medicine: A Systematic Scoping Review,” Journal of Evaluation in Clinical Practice 29, no. 3 (April 2023): 554–64, https://doi.org/10.1111/jep.13789. [xi] Kimmelman and Tannock, “The Paradox of Precision Medicine.” [xii] Vogt and Hofmann, 1206. [xiii] Vogt and Hofmann, 1206. [xiv] Vogt and Hofmann, 1206. [xv] Vogt and Hofmann, 1207. [xvi] Vogt and Hofmann, 1207. [xvii] Vogt and Hofmann, 1207. [xviii] Vogt and Hofmann, 1210. [xix] Mehar Sahu et al., “Chapter Three - Artificial Intelligence and Machine Learning in Precision Medicine: A Paradigm Shift in Big Data Analysis,” in Progress in Molecular Biology and Translational Science, ed. David B. Teplow, vol. 190, 1 vols., Precision Medicine (Academic Press, 2022), 57–100, https://doi.org/10.1016/bs.pmbts.2022.03.002. [xx] Stefan Feuerriegel et al., “Causal Machine Learning for Predicting Treatment Outcomes,” Nature Medicine 30, no. 4 (April 2024): 958–68, https://doi.org/10.1038/s41591-024-02902-1. [xxi] Sunderland Baker et al., “Ethical Considerations in Closed Loop Deep Brain Stimulation,” Deep Brain Stimulation 3 (October 1, 2023): 8–15, https://doi.org/10.1016/j.jdbs.2023.11.001. [xxii] David Haslacher et al., “AI for Brain-Computer Interfaces,” 2024, 7, https://doi.org/10.1016/bs.dnb.2024.02.003. [xxiii] Burdette and Swartz, “Chapter 4 - Responsive Neurostimulation,” 103–4; “Premarket Approval (PMA),” https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpma/pma.cfm?id=P100026. [xxiv] Burdette and Swartz, “Chapter 4 - Responsive Neurostimulation,” 104. [xxv] Burdette and Swartz, 126. [xxvi] Sean L. Metzger et al., “A High-Performance Neuroprosthesis for Speech Decoding and Avatar Control,” Nature 620, no. 7976 (August 2023): 1037–46, https://doi.org/10.1038/s41586-023-06443-4. [xxvii] Hao Fang and Yuxiao Yang, “Predictive Neuromodulation of Cingulo-Frontal Neural Dynamics in Major Depressive Disorder Using a Brain-Computer Interface System: A Simulation Study,” Frontiers in Computational Neuroscience 17 (March 6, 2023), https://doi.org/10.3389/fncom.2023.1119685; Mahsa Malekmohammadi et al., “Kinematic Adaptive Deep Brain Stimulation for Resting Tremor in Parkinson’s Disease,” Movement Disorders 31, no. 3 (2016): 426–28, https://doi.org/10.1002/mds.26482. [xxviii] Young-Hoon Nho et al., “Responsive Deep Brain Stimulation Guided by Ventral Striatal Electrophysiology of Obsession Durably Ameliorates Compulsion,” Neuron 0, no. 0 (October 20, 2023), https://doi.org/10.1016/j.neuron.2023.09.034. [xxix] Nho et al. [xxx] Nho et al.; Erik Robinson, “Brain Implant at OHSU Successfully Controls Both Seizures and OCD,” OHSU News, accessed March 3, 2024, https://news.ohsu.edu/2023/10/25/brain-implant-at-ohsu-successfully-controls-both-seizures-and-ocd. [xxxi] Awuah et al., “Bridging Minds and Machines”; Haslacher et al., “AI for Brain-Computer Interfaces.” [xxxii] Awuah et al., “Bridging Minds and Machines.” [xxxiii] Sara Green, Barbara Prainsack, and Maya Sabatello, “The Roots of (in)Equity in Precision Medicine: Gaps in the Discourse,” Personalized Medicine 21, no. 1 (January 2024): 5–9, https://doi.org/10.2217/pme-2023-0097. [xxxiv] Green, Prainsack, and Sabatello, 7. [xxxv] Robyn Bluhm and Kirstin Borgerson, “An Epistemic Argument for Research-Practice Integration in Medicine,” The Journal of Medicine and Philosophy: A Forum for Bioethics and Philosophy of Medicine 43, no. 4 (July 9, 2018): 469–84, https://doi.org/10.1093/jmp/jhy009. [xxxvi] Vijay Mahant, “‘Right-to-Try’ Experimental Drugs: An Overview,” Journal of Translational Medicine 18 (June 23, 2020): 253, https://doi.org/10.1186/s12967-020-02427-4. [xxxvii] Michael S. Okun et al., “Deep Brain Stimulation in the Internal Capsule and Nucleus Accumbens Region: Responses Observed during Active and Sham Programming,” Journal of Neurology, Neurosurgery & Psychiatry 78, no. 3 (March 1, 2007): 310–14, https://doi.org/10.1136/jnnp.2006.095315. (shrink)

This is the first detailed study to explore the little-understood notions of "knowing who someone is," "knowing a person's identity," and related locutions. It locates these notions within the context of a general theory of believing and a semantical theory of belief- and knowledge-ascriptions.The books's main contention is that what one knows, when one knows who someone is, is not normally an identity in the numerical sense of "a = b," but rather a certain sort of predication to know (...) who someone is is just to know that that person is F, where "F" is a predicate that is "important," in a technical sense defined by the authors, for the purposes determined by context. Their book offers a rigorous formal semantics for ascriptions of knowing and of knowing-who in particular, solving such well-known problems and paradoxes as Kripke's Puzzle, and Quines difficulties with de re belief, along the way.The authors apply their analysis to each of several important issues in philosophy of language, philosophy of mind, and ethical theory in which the previously unexamined notion of "knowing who" has loomed large-the mechanics of linguistic referring, the foundations of epistemic logic, problems of self-knowledge and self-regarding belief, universalizability and "Golden Rule" arguments in ethics, and moral "personalism" versus "impartialism."Stephen Boër is Professor of Philosophy at the Ohio State University. William Lycan is Professor of Philosophy at the University of North Carolina and author of Logical Form in Natural Language. A Bradford Book. (shrink)

There are two main theories about the persistence of objects through time: endurantism and perdurantism. Endurantists hold that objects are three-dimensional, have only spatial parts, and wholly exist at each moment of their existence. Perdurantists hold that objects are four-dimensional, have temporal parts, and only partly exist at each moment of their existence. In this paper we argue that endurantism is poorly suited to describe the persistence of objects in a world governed by Special Relativity, and can accommodate a (...) relativistic world only at a high price, one that we argue is not worth paying. Perdurantism, on the other hand, fits beautifully with our current scientific understanding of the world. Furthermore, we make this argument from implications of the Lorentz transformations, without appeals to geometrical interpretations, dimensional analogies, or auxillary premises like temporal eternalism. (shrink)

Leszek Kolakowski, an eminent philosopher known mainly outside his native Poland for Main Currents of Marxism, was an enormously influential public figure in Poland. He was awarded the Order of the White Eagle when Poland was liberated and went into exile in 1968, first to North America, where he continued to give active support and advice to Solidarity, and then to Oxford. Kolakowski, who became a Fellow of the British Academy in 1980, was buried in Poland with military honours (...) and a minute's silence in the national Parliament. Obituary by Steven Lukes FBA. (shrink)

DESCARTES'S MAIN ARGUMENTS FOR DUALISM--FROM HIS INABILITY\nTO CONCEIVE MIND "APART FROM" BODY AND FROM PSYCHIC\nSIMPLICITY--ARE ESSENTIALLY ALIKE. BUT BOTH ARE AMBIGUOUS:\nDESCARTES VACILLATES BETWEEN USING GOD TO "VALIDATE" AN\nALREADY GIVEN DUALIST CONCLUSION AND USING THE GUARANTEE TO\nINFER DUALISM FROM THE EPISTEMIC POSSIBILITY OF A\nDISEMBODIED MIND. HIS THEORY OF REPRESENTATION LEAD HIM TO\nCONFUSE THESE STRATEGIES AND TO OVERLOOK THE PROBLEMS OF\nEACH. NONETHELESS, DESCARTES ANTICIPATES KANT'S INSIGHTS\nINTO THE FAILURES OF TRADITIONAL PHILOSOPHY OF MIND.

This article presents a critique of an article previously featured in Nursing Philosophy (10: 26–33) by Ursula Naue and Thilo Kroll, who suggested that people living with dementia are assigned a negative status upon receipt of a diagnosis, holding the identity of the ‘demented other’. Specifically, in this critique, we suggest that unwitting use of the adjective ‘demented’ to define a person living with the condition is ill-informed and runs a risk of defining people through negative (self-)attributes, which has a (...) deleterious impact upon that person's social and relational personae. Moreover, use of the locution ‘demented’ reinforces a divide between the ‘demented’ (them) and the ‘healthy others’ (us). Social constructionist theory, malignant positioning and viewing people with dementia as semiotic subjects are the philosophical pillars through which we construct the main arguments of the critique. The article concludes with the voice of one of the authors, a younger person with dementia, asking for language in dementia care to be carefully reconsidered and reframed and for the recognition of the diagnosed person's agency in the conduct of their day-to-day lives. (shrink)

The philosophical, legal, and HCI literature concerning artificial intelligence (AI) has explored the ethical implications and values that these systems will impact on. One aspect that has been only partially explored, however, is the role of deception. Due to the negative connotation of this term, research in AI and Human–Computer Interaction (HCI) has mainly considered deception to describe exceptional situations in which the technology either does not work or is used for malicious purposes. Recent theoretical and historical work, however, has (...) shown that deception is a more structural component of AI than it is usually acknowledged. AI systems that enter in communication with users, in fact, forcefully invite reactions such as attributions of gender, personality and empathy, even in the absence of malicious intent and often also with potentially positive or functional impacts on the interaction. This paper aims to operationalise the Human-Centred AI (HCAI) framework to develop the implications of this body of work for practical approaches to AI ethics in HCI and design. In order to achieve this goal, we take up the analytical distinction between “banal” and “strong” deception, originally proposed in theoretical and historical scholarship on AI (Natale in Deceitful media: artificial intelligence and social life after the turing test, Oxford University Press, New York, 2021), as a starting point to develop ethical reflections that will empower designers and developers with practical ways to solve the problems raised by the complex relationship between deception and communicative AI. The paper considers how HCAI can be applied to conversational AI (CAI) systems in order to design them to develop banal deception for social good and, at the same time, to avoid its potential risks. (shrink)

This paper has three main aims. The first is to provide a critical assessment of two rival concepts of suffering, that proposed by Cassell and that proposed in this journal by van Hooft. The second aim of the paper is to sketch a more plausible concept of suffering, one which derives from a Wittgensteinian view of linguistic meaning. This more plausible concept is labeled an ‘intuitive concept’. The third aim is to assess the prospects for scientific understanding of suffering.

This book seeks to arrive at a better understanding of the relationships between the objective and subjective aspects of time. It discusses the existence of fluent time, a controversial concept in many areas, from philosophy to physics. Fluent time is understood as directional time with a past, a present and a future. We experience fluent time in our lives and we adopt a temporal perspective in our ways of knowing and acting. Nevertheless, the existence of fluent time has been debated (...) for both philosophical and scientific reasons, thus creating a rift between the subjective and objective aspects of time. Starting from the basic notion of points of view, or perspectives, this book explores the relationships between objective or external time, as it has been conceptualized by science, and subjective or internal time, which is involved in our lived experiences. It establishes a general framework encompassing the nature, structure and mode of existence of points of view, in which the objective and subjective aspects of time can be integrated. The book mainly addresses researchers and postgraduates in philosophy and logic. Additionally, it offers inspiration for physicists and computer scientists involved in the modeling and simulation of complex behaviors for which the representation of internal time should be considered together with the notion of objective, external time. (shrink)

In this volume, author Steven L. Bindeman presents a survey of the key figures in postmodern antiphilosophy. Noting that the main thrust of their work can be found in their need to respond to the threat of nihilism, he is guided by the question, if the path to abstract truth is no longer viable, what then? He shows how the antiphilosophers turn their focus on the complexity of lived experience in place of the search for certainty, which was (...) in their view what previously had guided the dominating discourse of the modernist philosophical tradition. Through close examination of a broad variety of texts, Bindeman illuminates how the antiphilosophers initiate a new way of doing philosophy, one which prefers to examine the question, Does it work? instead of, Is it true? Moreover, Bindeman demonstrates how the antiphilosophers are united in questioning the centrality of the great cornerstones of western metaphysics - time, self, universe, and God - because of their insistence that there is no way to reach beyond any of these words to the actual things to which they refer. Utilizing the exposed, significant fault in the foundation of all philosophical systems, "The Antiphilosophers" delivers new insight concerning the issue of how we should relate to the resultant chaos. Written with a rare combination of philosophical rigor and clarity of expression, Bindeman's work will be of interest to students and scholars of postmodern philosophy. (shrink)

This paper provides a translation of the first twenty-five cases of the gongan collection, Tongxuan’s 100 Questions (Tongxuan Baiwen《玄百問》), which features terse responses to Tongxuan’s queries proffered by Wansong Xingxiu along with verse comments added by his main disciple Linquan Conglun. The conciseness expressed by leading Caodong school thinkers at the dawn of the Yuan period creates a minimalist discourse replete with paradox, indirection, and deceptively artless depictions of nature to disclose a pragmatist view of realization that seeks to (...) situate Chan as the basis for the three teachings of Confucianism, Daoism, and Buddhism. (shrink)

Dennett and Kinsbourne ([1992]) argue that metacontrast backward visual masking provides a clear illustration that ‘there is really only a verbal difference’ between two versions of the Cartesian Theater model of the mind. This alleged lack of a distinction is both the crucial premise of their main argument against the Cartesian Theater and a motivator for accepting their own Multiple Drafts model. I argue that metacontrast reveals a difference between the two versions of the Cartesian Theater that meets criteria (...) found in (Dennett and Kinsbourne [1992]) for determining such a difference. This difference undermines the soundness of their argument against the Cartesian Theater, and exerts pressure on Dennett and Kinsbourne to offer a more detailed articulation of their model. 1. Introduction2. Brief Explanation of Metacontrast Backward Visual Masking3. The Stalinesque and Orwellian Models of Metacontrast 3.1. Criteria for determining a difference4. A Difference That Makes a Difference 4.1. Skeptical hypothesis objection5. Other Objections and Replies 5.1. Straw person objection5.2. Corroborative issues objection6. Conclusion. (shrink)

This paper attempts to give an experiential explanation of the phenomenon of immunity to error through misidentification in some of our judgments about ourselves. The main idea is that in most of these judgments we respond to the type of presentation -- e.g., proprioceptive -- and not to presented properties of the perceived object.

This paper argues that transcendental phenomenology (here represented by Edmund Husserl) can accommodate the main thesis of semantic externalism, namely, that intentional content is not simply a matter of what is ‘in the head,’ but depends on how the world is. I first introduce the semantic problem as an issue of how linguistic tokens or mental states can have ‘content’—that is, how they can set up conditions of satisfaction or be responsive to norms such that they can succeed or (...) fail at referring. The standard representationalist view—which thinks of the problem in first-person terms—is contrasted with Brandom’s pragmatic inferentialist approach, which adopts a third-person stance. The rest of the paper defends a phenomenological version of the representationalist position (seeking to preserve its first-person stance) but offers a conception of representation that does not identify it with an entity ‘in the head.’ The standard view of Husserl as a Cartesian internalist is undermined by rejecting its fundamental assumption—that Husserl’s concept of the ‘noema’ is a mental entity—and by defending a concept of ‘phenomenological immanence’ that has a normative, rather than a psychological, structure. Finally, it is argued that phenomenological immanence cannot be identified with ‘consciousness’ in Husserl’s sense, though consciousness is a necessary condition for it. (shrink)

Spinoza's ethics is founded on the idea that we are egoists who should do nothing but search our own advantage , but that in doing so, this is when we are most virtuous, most moral, and most social . Community, taken in any sense stronger than a mere collection of things, only occurs, then, when each is drawn to seek his self-interest. ;Spinoza would hold that no study of ethics can be done in a metaphysical vacuum . To discuss the (...) ethics of an individual existing in community, one must first address the metaphysical foundations of the individual, its rights, and its place in community. To this end, the greater part of this work examines just those metaphysical bases which define an individual and how it relates in community. The analysis is textually based; focusing on how Spinoza uses certain terms , we attempt to understand what Spinoza understood to be an individual, community, right, etc. Then, because society affects an individual and the individual in turn affects society, the study looks at human individuals and their affects, that is, how humans affect and are affected by other humans. Just as a group of rocks makes only a pile and not what might be called a community, so too a group of human individuals does not necessarily make a society. The move from many individuals to one community is examined. ;Finally, after the metaphysical and psychological considerations are established, the study addresses its main question, that is, the value that should be accorded to a particular human life vis-a-vis the society in which the person lives. The study touches, therefore, questions concerning capital punishment, euthanasia, assisted suicide, and even abortion. The surprising conclusion is that Spinoza's ethics do allow for and can support what could be called a consistent human life ethic in which the right to life remains primary. (shrink)

This Handbook provides a comprehensive single-volume treatment of Fichte’s philosophy. In addition to offering new researchers an authoritative introduction and orientation to Fichtean thought, the volume also surveys the main scholarly and philosophical controversies regarding Fichtean interpretation, and defends a range of philosophical theses in a way that advances the scholarly discussion. Fichte is the first major philosopher in the post-Kantian tradition and the first of the great German Idealists, but he was no mere epigone of Kant or precursor (...) to Hegel. His work speaks powerfully and originally to a wide range of issues of enduring concern, and his many innovations importantly anticipate major developments, including absolute idealism, phenomenology, and existentialism. He is therefore not only a path-breaking thinker but also a pivotal figure in Western intellectual history. Wide-ranging, well-organised and timely, this key volume makes Fichte’s work both accessible and relevant. It is essential reading for scholars, graduate researchers and advanced students interested in Fichte, German Idealism, and the history of nineteenth-century philosophy in the West. (shrink)

Thomas Piketty’s blockbuster Capital in the Twenty-First Century was followed by the publication of Capital and Ideology in early 2020. This paper looks at the differences between the two books, and provides an analysis and a critique of the main advances in the new book. First, Piketty drops r>g as an explanation for rising inequality. Instead, inequality is generated and constrained by economic power supported by an ideology. Second, there is a focus on the political consequences of inequality, including (...) the rise of right-wing populism and the election of people like Donald Trump. Third, there is a new policy proposal-changes in corporate governance that gives labor and government seats on the Board of Directors of public corporations. (shrink)

It is common knowledge that Martin Heidegger’s attempts at engaging non-Western philosophy are very much a construct of his own making. This article in no way seeks to disagree with those observations, but argues two things: first, that Heidegger’s “dialogue” with his two main other sources of inspiration, the ancient Greek thinkers and the German poets, is not different in kind or in principle from his engagement with East Asia. One can of course quite easily argue that Heidegger’s (...) class='Hi'>main interest was the ancient Greek thinkers, and then the poets, and only lastly Asia. But this hierarchy in preference does not make Heidegger’s approach different in kind or in principle. Second, I argue that there is an important place in comparative philosophy for the type of thinking displayed by Heidegger in this kind of Auseinandersetzung (confrontation) with—and “appropriation” of—Asian (or Greek, or Poetic) thought. (shrink)

This paper is an attempt to provide a critical evaluation of the theory of disability put forward by Lennart Nordenfelt. The paper is in five sections. The first sets out the main elements of Nordenfelt's theory. The second section elaborates the theory further, identifies a tension in the theory, and three kinds of problems for it. The tension derives from Nordenfelt's attempt to respect two important but conflicting constraints on a theory of health. The problems derive from characterisation of (...) the goals of persons; the difficulty which Nordenfelt has in respecting the plausible view that there is a distinction between illness and disability; and the presence in the theory of other strongly counter-intuitive implications. In section three a defence of Nordenfelt is attempted from within the resources available within his own theory. This defence seeks to exploit his distinctions between a person who is ill and one who is generally disabled and that between first- and second-order disabilities. However, it is concluded that there are insufficient resources within Nordenfelt's theory to fend off the criticisms developed in section two. The fourth section of the paper attempts a defence of Nordenfelt. It is claimed that introduction of the concept of capacity helps to explain differences between problem cases in the theory. Finally, it is shown that at least two important constraints on any theory of disability emerge from the preceding discussion. (shrink)

Reasoning almost always occurs in the face of incomplete information. Such reasoning is nonmonotonic in the sense that conclusions drawn may later be withdrawn when additional information is obtained. There is an active literature on the problem of modeling such nonmonotonic reasoning, yet no category of method-let alone a single method-has been broadly accepted as the right approach. This paper introduces a new method, called sweeping presumptions, for modeling nonmonotonic reasoning. The main goal of the paper is to provide (...) an example-driven, nontechnical introduction to the method of sweeping presumptions, and thereby to make it plausible that sweeping presumptions can usefully be applied to the problems of nonmonotonic reasoning. The paper discusses a representative sample of examples that have appeared in the literature on nonmonotonic reasoning, and discusses them from the point of view of sweeping presumptions. (shrink)

The period 1944-1950 witnessed the successful reconstruction of the Belgian Socialist Party. Despite some modifications of structure and leadership personnel, the party retained many of its pre-war characteristics. There was no significant modernization of doctrine. In particular, its role as a party of government was accentuated. The PSB played amajor role in increasing social welfare programs and restoring the Belgian economy, but made few structural reforms. Despite opposition to a division of the world into blocs, it was eventually forced into (...) the American camp. The PSB's main political accomplishment was preventing the return to the throne of Leopold. By the end of this period, the PSB had largely become a party of the status quo. (shrink)

PLEASE NOTE: This is the corrected 2nd eBook edition, 2021. ●●●●● _Critique of Impure Reason_ has now also been published in a printed edition. To reduce the otherwise high price of this scholarly, technical book of nearly 900 pages and make it more widely available beyond university libraries to individual readers, the non-profit publisher and the author have agreed to issue the printed edition at cost. ●●●●● The printed edition was released on September 1, 2021 and is now available through (...) all booksellers, including Barnes & Noble, Amazon, and brick-and-mortar bookstores under ISBN 978-0-578-88646-6. ●●●●● In light of the length of this book, readers who would like to have a more detailed description of the book's objectives and method may find it helpful to read the detailed and clearly written Wikipedia entry about this work: From the Wikipedia search page, use the search phrase "Critique of Impure Reason". At least at the time of this writing (11/29/2021), the Wikipedia entry is well-researched and accurate. ●●●●● In addition, a "Primer on Bartlett's CRITIQUE OF IMPURE REASON" has been made available by the author. It is available under its title through PhilPapers and other philosophy online archives. ●●●●● COMMENDATIONS OF THIS WORK, from the back cover of the published edition: ●●●●● “I admire its range of philosophical vision.” – Nicholas Rescher, Distinguished University Professor of Philosophy, University of Pittsburgh, author of more than 100 books. ●●●●● “Bartlett’s _Critique of Impure Reason_ is an impressive, bold, and ambitious work. Careful scholarship is balanced by original analyses that lead the reader to recognize the limits of meaning, knowledge, and conceptual possibility. The work addresses a host of traditional philosophical problems, among them the nature of space, time, causality, consciousness, the self, other minds, ontology, free will and determinism, and others. The book culminates in a fascinating and profound new understanding of relativity physics and quantum theory.” – Gerhard Preyer, Professor of Philosophy, Goethe-University, Frankfurt am Main, Germany, author of many books including _Concepts of Meaning_, _Beyond Semantics and Pragmatics_, _Intention and Practical Thought_, and _Contextualism in Philosophy_. ●●●●● “[This work’s] goal is of a unique and difficult species: Dr. Bartlett seeks to develop a formal logical calculus on the basis of transcendental philosophical arguments; in fact, he hopes that this calculus will be the formal expression of the transcendental foundation of knowledge.... I consider Dr. Bartlett’s work soundly conceived and executed with great skill.” – C. F. von Weizsäcker, philosopher and physicist, former Director, Max-Planck-Institute, Starnberg, Germany. ●●●●● “Bartlett has written an American “Prolegomena to All Future Metaphysics.” He aims rigorously to eliminate meaningless assertions, reach bedrock, and place philosophy on a firm foundation that will enable it, like science and mathematics, to produce lasting results that generations to come can build on. This is a great book, the fruit of a lifetime of research and reflection, and it deserves serious attention.” — Martin X. Moleski, former Professor, Canisius College, Buffalo, NY, studies of scientific method, the presuppositions of thought, and the self-referential nature of epistemology. ●●●●● “Bartlett has written a book on what might be called the underpinnings of philosophy. It has fascinating depth and breadth, and is all the more striking due to its unifying perspective based on the concepts of reference and self-reference.” – Don Perlis, Professor of Computer Science, University of Maryland, author of numerous publications on self-adjusting autonomous systems and philosophical issues concerning self-reference, mind, and consciousness. ●●●●● ●●●●● The _Critique of Impure Reason: Horizons of Possibility and Meaning_ comprises a major and important contribution to philosophy. Thanks to the generosity of its publisher, this massive 885-page volume has been published as a free open access eBook (3.75MB) as well as an open access printed edition. It inaugurates a revolutionary paradigm shift in philosophical thought by providing compelling and long-sought-for solutions to a wide range of philosophical problems. In the process, the work fundamentally transforms the way in which the concepts of reference, meaning, and possibility are understood. The book includes a Foreword by the celebrated German philosopher and physicist Carl Friedrich von Weizsäcker. ●●●●● In Kant’s _Critique of Pure Reason_ we find an analysis of the preconditions of experience and of knowledge. In contrast, but yet in parallel, the new _Critique_ focuses upon the ways—unfortunately very widespread and often unselfconsciously habitual—in which many of the concepts that we employ _conflict_ with the very preconditions of meaning and of knowledge. ●●●●● This is a book about the boundaries of frameworks and about the unrecognized conceptual confusions in which we become entangled when we attempt to transgress beyond the limits of the possible and meaningful. We tend either not to recognize or not to accept that we all-too-often attempt to trespass beyond the boundaries of the frameworks that make knowledge possible and the world meaningful. ●●●●● The _Critique of Impure Reason_ proposes a bold, ground-breaking, and startling thesis: that a great many of the major philosophical problems of the past can be solved through the recognition of a viciously deceptive form of thinking to which philosophers as well as non-philosophers commonly fall victim. For the first time, the book advances and justifies the criticism that a substantial number of the questions that have occupied philosophers fall into the category of “impure reason,” violating the very conditions of their possible meaningfulness. ●●●●● The purpose of the study is twofold: first, to enable us to recognize the boundaries of what is referentially forbidden—the limits beyond which reference becomes meaningless—and second, to avoid falling victims to a certain broad class of conceptual confusions that lie at the heart of many major philosophical problems. As a consequence, the boundaries of _possible meaning_ are determined. ●●●●● Bartlett, the author or editor of more than 20 books, is responsible for identifying this widespread and delusion-inducing variety of error, _metalogical projection_. It is a previously unrecognized and insidious form of erroneous thinking that undermines its own possibility of meaning. It comes about as a result of the pervasive human compulsion to seek to transcend the limits of possible reference and meaning. ●●●●● Based on original research and rigorous analysis combined with extensive scholarship, the _Critique of Impure Reason_ develops a self-validating method that makes it possible to recognize, correct, and eliminate this major and pervasive form of fallacious thinking. In so doing, the book provides at last provable and constructive solutions to a wide range of major philosophical problems. ●●●●● CONTENTS AT A GLANCE ▪▪▪▪▪ Preface ▪▪▪▪▪ Foreword by Carl Friedrich von Weizsäcker ▪▪▪▪▪ Acknowledgments ▪▪▪▪▪ Avant-propos: A philosopher’s rallying call ▪▪▪▪▪ Introduction ▪▪▪▪▪ A note to the reader ▪▪▪▪▪ A note on conventions ▪▪▪▪▪ ▪▪▪▪▪ ▪▪▪▪▪ PART I ▪▪▪▪▪ ▪▪▪▪▪ WHY PHILOSOPHY HAS MADE NO PROGRESS AND HOW IT CAN ▪▪▪▪▪ 1 Philosophical-psychological prelude ▪▪▪▪▪ 2 Putting belief in its place: Its psychology and a needed polemic ▪▪▪▪▪ 3 Turning away from the linguistic turn: From theory of reference to metalogic of reference ▪▪▪▪▪ 4 The stepladder to maximum theoretical generality ▪▪▪▪▪ ▪▪▪▪▪ ▪▪▪▪▪ PART II ▪▪▪▪▪ THE METALOGIC OF REFERENCE ▪▪▪▪▪ A New Approach to Deductive, Transcendental Philosophy ▪▪▪▪▪ 5 Reference, identity, and identification ▪▪▪▪▪ 6 Self-referential argument and the metalogic of reference ▪▪▪▪▪ 7 Possibility theory ▪▪▪▪▪ 8 Presupposition logic, reference, and identification ▪▪▪▪▪ 9 Transcendental argumentation and the metalogic of reference ▪▪▪▪▪ 10 Framework relativity ▪▪▪▪▪ 11 The metalogic of meaning ▪▪▪▪▪ 12 The problem of putative meaning and the logic of meaninglessness ▪▪▪▪▪ 13 Projection ▪▪▪▪▪ 14 Horizons ▪▪▪▪▪ 15 De-projection ▪▪▪▪▪ 16 Self-validation ▪▪▪▪▪ 17 Rationality: Rules of admissibility ▪▪▪▪▪ ▪▪▪▪▪ ▪▪▪▪▪ PART III ▪▪▪▪▪ PHILOSOPHICAL APPLICATIONS OF THE METALOGIC OF REFERENCE ▪▪▪▪▪ Major Problems and Questions of Philosophy and the Philosophy of Science ▪▪▪▪▪ 18 Ontology and the metalogic of reference ▪▪▪▪▪ 19 Discovery or invention in general problem-solving, mathematics, and physics ▪▪▪▪▪ 20 The conceptually unreachable: “The far side” ▪▪▪▪▪ 21 The projections of the external world, things-in-themselves, other minds, realism, and idealism ▪▪▪▪▪ 22 The projections of time, space, and space-time ▪▪▪▪▪ 23 The projections of causality, determinism, and free will ▪▪▪▪▪ 24 Projections of the self and of solipsism ▪▪▪▪▪ 25 Non-relational, agentless reference and referential fields ▪▪▪▪▪ 26 Relativity physics as seen through the lens of the metalogic of reference ▪▪▪▪▪ 27 Quantum theory as seen through the lens of the metalogic of reference ▪▪▪▪▪ 28 Epistemological lessons learned from and applicable to relativity physics and quantum theory ▪▪▪▪▪ ▪▪▪▪▪ PART IV ▪▪▪▪▪ HORIZONS ▪▪▪▪▪ 29 Beyond belief ▪▪▪▪▪ 30 _Critique of Impure Reason_: Its results in retrospect ▪▪▪▪▪ ▪▪▪▪▪ SUPPLEMENT ▪▪▪▪▪ The Formal Structure of the Metalogic of Reference ▪▪▪▪▪ APPENDIX I ▪▪▪▪▪ The Concept of Horizon in the Work of Other Philosophers ▪▪▪▪▪ APPENDIX II ▪▪▪▪▪ Epistemological Intelligence ▪▪▪▪▪ References ▪▪▪▪▪ Index ▪▪▪▪▪ About the author. 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Broadly speaking, exclusion for disabled people can be understood as a general lack of social and political integration within a society. Inequalities arising from the multi-dimensional causes of exclusion not only include poverty, but more fundamental aspects of societal membership such as social participation, financial autonomy, friendship, sexual citizenship, and accessibility. The articles of this thesis offer insight to the nature of the experience of exclusion for disabled people by considering specific examples of exclusion (such as the exclusion from sexual (...) citizenship, discussed in Articles I and II), and a new theoretical approach to disability (advanced in Article III). -/- Analysis of the nature of exclusion for disabled people reveals a unique set of multi-dimensional problems, and despite efforts from the disability rights community and an increased academic interest in disability studies, there has been a limited incorporation of holistic or transdisciplinary approaches to the phenomenon in works of praxis and in governmental policy. Seeking to highlight and ameliorate the experience of exclusion for disabled people, disability rights organisations advocate for greater societal integration and inclusion into the social fabric of society by offering revisionary theoretical interpretations of disability in an effort to steer social change — a devoir to which the works of this thesis contribute academically. -/- Focussing on the interplay between the nature of exclusion, rights, and basic needs, this thesis investigates the limits of the welfare state’s obligations to afford disabled people a life of eu zen, argues for greater obligations in areas such as sexual citizenship, inclusion, and presents an alternate theory of disability. The Introduction situates the articles of this thesis within a wider theoretical context that highlights the importance of social context, and focusses on the nature of exclusion and inclusion for disabled people as a complex set of societal and political disadvantages which go beyond simple poverty and social disenfranchisement. The main claim of this thesis is that the experience of exclusion for disabled people constitutes a multi-faceted and interconnected set of disadvantages and barriers that constitute a greater and more substantive set of exclusions than those experienced by other excluded groups. (shrink)

It is obvious that a great many of the things that we know we know because we learn them in conversation with others, conversations in which it is the intention of our interlocutor to inform us of something. It might be thought that only assertoric acts are informative. I shall argue that there is a range of conversational interventions that have this characteristic, including speech acts, presuppositions and conversational implicatures. The main focus of the paper is a discussion of (...) the different norms, both moral and epistemological, that entitle us to believe what we learn from conversations. I compare our entitlement to believe what we learn from conversation with our entitlements to believe what we learn from perception. In providing an account of our epistemic warrant for our knowledge gained in conversation with ours, I draw on the work of Tyler Burge (1993 and 1997). (shrink)

Control of our own beliefs is allegedly required for the truth of epistemic evaluations, such as S ought to believe that p , or S ought to suspend judgment (and so refrain from any belief) whether p . However, we cannot usually believe or refrain from believing at will. I agree with a number of recent authors in thinking that this apparent conflict is to be resolved by distinguishing reasons for believing that give evidence that p from reasons that make (...) it desirable to believe that p whether or not p is true. I argue however that there is a different problem, one that becomes clearer in light of this solution to the first problem. Someone’s approval of our beliefs is at least often a non-evidential reason to believe, and as such cannot change our beliefs. Ought judgments aim to change the world. But ‘ought to believe’ judgments can’t do that by changing the belief, if they don’t give evidence. So I argue that we should instead regard epistemic ought judgments as aimed mainly at influencing assertions that express the belief and other actions based on the belief, in accord with recent philosophical claims that we have epistemic norms for assertion and action. (shrink)

In an attempt to revive discussion of the argument from illusion this paper amends the classic version of the argument to avoid Austin's main objection. It then develops and defends a version of the intentional object reply to the argument, arguing that an "unendorsed story" account of reports of dreams and hallucinations avoids commitment to nonexistent objects.

Steven Nadler presents the first English translation of a seminal work in the history of early modern philosophy. Géraud de Cordemoy's Six Discourses on the Distinction Between the Soul and the Body offers an account of the mind and the body in a human being. Cordemoy is an unorthodox Cartesian who opts for an atomist conception of body and matter. In this groundbreaking treatise, he also presents one of the earliest arguments for an occasionalist account of causation, with God (...) serving as the true cause of bodily motions in the world and of ideas in the mind. Nadler also includes the first English translation of Cordemoy's short Treatises on Metaphysics, which were probably written soon after the Discourses, and extend his discussion of mind-body union with consideration of human freedom and happiness. The introduction provides a biographical and historical context for Cordemoy's work and a study of his main philosophical doctrines, including his influence on later thinkers. (shrink)

The issue of meaningful yet unexpressed background - to language, to our experiences of the body - is one whose exploration is still in its infancy. There are various aspects of "invisible," implicit, or background experiences which have been investigated from the viewpoints of phenomenology, cognitive psychology, and linguistics. I will claim that James, as explicated by Gurwitsch and others, has analyzed the phenomenon of fringes in such a way as to provide a structural framework from which to investigate and (...) better understand those ideas or concepts that are unexpressed, particularly those experienced in the sense of being sought-after. I will consider Johnson?s conception of the image -schematic gestalt as a way of bridging the descriptive gap between phenomenology and cognitive psychology. Starting from an analysis of the fringes, I will turn to a consideration of the of tip-of-tongue state, as a kind of feeling-of-knowing state, from a variety of approaches, focusing mainly on cognitive psychology and phenomenology. I will then integrate a phenomenological analysis of these experiences, from the James/Gurwitsch structural viewpoint, with a cognitive/ phenomenological analysis in terms of ISGs; and further integrate that with a cognitive/functional analysis of consciousness. I will employ this synthesis of three viewpoints to explore the thesis that the TOT state and similar experiences may relate to the gestalt nature of schemas as well as to particular cues, and may thus be experienced as an aspect of the continuum to the general background to all our conscious experiences. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Spinoza et le christianisme by Henri LauxSteven NadlerHenri Laux. Spinoza et le christianisme. Paris: Presses Universitaires de France, 2022. Pp. 241. Paperback, €19.00.No one should be surprised by the popularity that Spinoza’s philosophy continues to enjoy today, within academia and even beyond. His bold ideas in metaphysics, ethics, politics, and religion seem to remain vitally relevant and continue to inspire, certainly more so than those of his contemporaries. (...) As the Spinoza scholar Henri Laux puts it at the beginning of his new book, “La pensée de Spinoza s’affirme comme l’une des plus novatrices de la modernité... elle stimule aujourd’hui la réflexion de bon nombre des champs de savoir: anthropologie, sociologie, psychanalyse, politique, économie, écologie, biologie, etc.” (9).But there is at least one domain where Spinoza’s alleged relevance may be rather unexpected: Christian theology. “Un terrain de rencontre, est-il possible?” Laux asks. “Spinoza, peut-il intéresser le christianisme aujourd’hui?” On the one hand, Spinoza’s rejection of the providential deity of the Abrahamic prophets and his dismissal of anything resembling traditional Christian theology as irrational superstition would seem to rule him out as a participant in typical theological conversations about God, the meaning of life, and death. On the other hand, there surely is no longer a need among theologians to attack and “refute” Spinoza; that ship sailed a long time ago. Thus, it is certainly not a surprise that, as Laux notes, “la théologie chrétienne a largement ignoré Spinoza” (14).And yet, Spinoza was writing for, among others, Christian theologians. His intended readers were not, to be sure, the more orthodox predikanten of the Dutch Reformed Church, the Voetians and Counter-Remonstrants who so viciously attacked him in his time. But the Theological-Political Treatise was written, at least in part, for more liberal-minded Christian thinkers—including Spinoza’s Collegiant friends—who might give his reading of the Bible and his reductive understanding of Christ’s universal moral message a fair hearing. At the same time that Spinoza attacks Christianity as an organized religion (“ses pratiques et ses énoncés,” Laux notes [11]), he elevates Christ as the most enlightened and philosophical of all prophets, one who spoke with God not merely through the imagination but with the intellect, “mind to mind.” To the question “Spinoza peut-il intéresser le christianisme?” Laux responds with a definite oui.The first section of the book, “Spinoza et le christianisme de son temps, un état des relations,” is devoted to a presentation of the main themes of Spinoza’s philosophy and the reactions they generated among his contemporaries. On the one hand, Spinoza’s attack on Christianity might seem to be directed primarily at the mendacious but historically contingent practices of the theologians—and especially their misuse of the Bible to manipulate the passions of ordinary people—rather than Christianity’s essential principles. And yet, Laux argues, Spinoza’s conception of God (Deus sive Natura) goes right to “l’essentiel du christianisme” and represents, as any reader of the Ethics knows, “une rupture radicale” with Christian theology. Then there is Spinoza’s rejection of the Trinity and the Incarnation and Resurrection of Christ, at least as these fundamental dogmas are literally understood to be supernatural affairs. “La radicalité de Spinoza à propos de Dieu et du Christ ébranle les fondements de la religion chrétienne” (42). In light of Spinoza’s “athéisme” and the “fatale nécessité” of his metaphysics, not to mention the absence of original sin and any absolute, transcendent, nonrelative moral values, what might Christian theologians find in Spinoza’s philosophy that is salvageable and useful for their own intellectual and spiritual purposes? [End Page 664]For most of Spinoza’s contemporaries, the answer was: absolutely nothing. The vicious onslaught of seventeenth-century critics, and not just theologians, was directed not just at the theological and metaphysical principles that undermined central Christian doctrines, but especially at their alleged practical implications for everyday moral behavior. But, Laux insists, things are not as simple as they appear. Spinoza’s denials of atheism are to be taken seriously, and they reveal, in... (shrink)

Provides a concise introduction to ethics or moral philosophy, surveying the main ideas of moral philosophy and discussing its controversial areas. In pursuing ethics' fundamental query, how we ought to live, this book devotes space - two chapters - to the question of what the best life is like.