Previous studies have reported abnormal amplitude of low-frequency fluctuation and regional homogeneity in patients with migraine without aura using resting-state functional magnetic resonance imaging. However, how whole brain functional connectivity pattern homogeneity and its corresponding functional connectivity changes in patients with migraine without aura is unknown. In the current study, we employed a recently developed whole brain functional connectivity homogeneity method to identify the voxel-wise changes of functional connectivity patterns in 21 patients with migraine without aura and 21 gender and (...) age matched healthy controls. Moreover, resting-state functional connectivity analysis was used to reveal the changes of corresponding functional connectivities. FcHo analyses identified significantly decreased FcHo values in the posterior cingulate cortex, thalamus, and left anterior insula in patients with migraine without aura compared to healthy controls. Functional connectivity analyses further found decreased functional connectivities between PCC and medial prefrontal cortex, between AI and anterior cingulate cortex, and between THA and left precentral gyrus. The functional connectivities between THA and PCG were negatively correlated with pain intensity. Our findings indicated that whole brain FcHo and connectivity abnormalities of these regions may be associated with functional impairments in pain processing in patients with migraine without aura. (shrink)

Liu, Xiaogan 劉笑敢 et. al., eds., Chinese Philosophy and Culture : Confucian Studies of Ming-Qing Period 中國哲學與文化: 明清儒學研究 Content Type Journal Article Pages 117-121 DOI 10.1007/s11712-010-9203-0 Authors Shaojin Chai, Department of Political Science, University of Notre Dame, 217 O’Shaughnessay Hall, Notre Dame, IN 46556, USA Journal Dao Online ISSN 1569-7274 Print ISSN 1540-3009 Journal Volume Volume 10 Journal Issue Volume 10, Number 1.

I first give a brief summary of a critique of the traditional theories of approximation and idealization; and after identifying one of the major roles of idealization as detaching component processes or systems from their joints, a detailed analysis is given of idealized laws – which are discoverable and/or applicable – in such processes and systems (i.e., idealized model systems). Then, I argue that dispositional properties should be regarded as admissible properties for laws and that such an inclusion supplies the (...) much needed connection between idealized models and the laws they `produce'' or `accommodate''. And I then argue that idealized law-statements so produced or accommodated in the models may be either true simpliciter or true approximately, but the latter is not because of the idealizations involved. I argue that the kind of limiting-case idealizations that produce approximate truth is best regarded as approximation; and finally I compare my theory with some existing theories of laws of nature.We seem to trace [in KingLear] ... the tendency of imagination toanalyse and abstract, to decomposehuman nature into its constituentfactors, and then to construct beings in whomone or more of these factors isabsent or atrophied or only incipient. (shrink)

The problem of transcendence and immanence is a central issue in every great religious tradition. It is indeed the understanding of the relation between the transcendent and man that determines the character of a religious faith. The transcendent, However, May assume different forms; it need not always be a supreme personal God in the judaeo-Christian sense. In the confucian tradition, Heaven is the transcendent; hence the problem of transcendence and immanence becomes the problem of heaven and man. In this article, (...) I have not followed a historical approach to trace the development of the idea of heaven and the idea of man in the confucian tradition. Instead, I have concentrated my studies on chung yung or the doctrine of the mean, Because the ideas developed in this document are most typical of the confucian reflection on the problem of transcendence and immanence. And I find that transcendence and immanence are a pair of interdependent concepts for the confucian philosophers. At the end of the paper, The contemporary significance of this view has also been considered. (shrink)

In this paper, a criticism of the traditional theories of approximation and idealization is given as a summary of previous works. After identifying the real purpose and measure of idealization in the practice of science, it is argued that the best way to characterize idealization is not to formulate a logical model – something analogous to Hempel's D-N model for explanation – but to study its different guises in the praxis of science. A case study of it is then made (...) in thermostatistical physics. After a brief sketch of the theories for phase transitions and critical phenomena, I examine the various idealizations that go into the making of models at three difference levels. The intended result is to induce a deeper appreciation of the complexity and fruitfulness of idealization in the praxis of model-building, not to give an abstract theory of it. (shrink)

This book is devoted to a thorough analysis of the role that models play in the practise of physical theory. The authors, a mathematical physicist and a philosopher of science, appeal to the logicians’ notion of model theory as well as to the concepts of physicists.

This study examines whether the gender of the directors on fully independent audit committees affects the ability of the committees in constraining earnings management and thus their effectiveness in overseeing the financial reporting process. Using a sample of 525 firm-year observations over the period 2003 to 2005, we are unable to identify an association between the proportion of female directors on audit committees and the extent of earnings management.

The objective of this paper is to show that, instead of quantum probabilities, wave packets are physically real. First, Cartwright's recent argument for the reality of quantum probabilities is criticized. Then, the notion of ‘physically real’ is precisely defined and the difference between wave functions and quantum probabilities clarified. Being thus prepared, some strong reasons are discussed for considering the wave packet to be physically real. Finding the reasons inconclusive, I explain how the Aharonov—Bohm effect delivers the final punch. I (...) conclude that wave packets are the quantum objects that underlie the indeterministic quantum processes and have the propensity of displaying probabilistic (or indeterministic) behavior. (shrink)

In his dialogue with Zai Wo about the three-year mourning, Confucius establishes a principle of 'justification by feeling at ease,' and insists that one should transcend natural desires by moral emotions. More significantly, he further regards kinship love as the ultimate root and supreme principle of human life. Thus, this dialogue contains almost all the basic elements of the Confucian spirit of consanguineous affection.

Physics seems to tell us that there are four fundamental force-fields in nature: the gravitational, the electromagnetic, the weak, and the strong (or interactions). But it also seems to tell us that gravity cannot possibly be a force-field, in the same sense as the other three are. And yet the search for a grand unification of all four force-fields is today one of the hottest pursuits. Is this the result of a simple confusion? This article aims at clarifying this situation (...) by (i) reviewing the gauge-field programme and its conception of unification of force-fields, (ii) examining the various attempts at a gauge theory of gravity, and (iii) articulating the nature of "gauging" and using it to explain the difference between gravity and the other force-fields. (shrink)

The Shape-of-a-Life phenomenon is widely recognized by philosophers of well-being: an upward life trajectory seems better than its downward equivalent if the sum of momentary well-being is held fixed. But what if we hold fixed the sum of momentary well-being in an upward trajectory, are certain ways to improve from the bad times better than the others? Velleman suggests that a redemptive trajectory is better than a bare upward trajectory. In this paper, I elaborate this proposal by developing a mediating (...) factor account of prudential redemption. I argue that, in redemptive trajectories, there is a mediating factor that bears certain relations with the negative and the positive events respectively, one that does not necessarily appear in bare upward trajectories. Prudential redemption, compared to mere improvement, can enhance a person’s lifetime well-being because a redeemed event is made less bad by virtue of the mediating factor. This result has implications for making decisions in the face of equally good options and for evaluating the rationality of honoring sunk costs. (shrink)

In this paper I construct Confucian moral realism as a metaethical theory that is compatible with, or even derivable from, traditional Confucianism. The paper is at once interpretative and constructive. In my analysis, Confucians can establish the realist's claims on moral properties because they embrace the view of a moralistic universe. Moral properties in Confucian ethics not only are presented as objective, naturalistic properties, but also are seen as 'causally efficacious'. There are several theses commonly endorsed by contemporary moral realists. (...) I will explain how many of the remarks by Confucius, Mencius, in Yijing, The Great Learning and The Doctrine of the Mean can be understood as implicit endorsements of these theses. I will also analyze the theses specific to Confucian moral realism. The paper will end with a brief defense of this form of realism. (shrink)

Food safety and food quality are two closely related aspects of the food management system. The difference between the two is that one keeps consumers safe while the other keeps consumers satisfied. This study examined the differences in how consumers value food safety and food quality with a focus on the influence of loss aversion on one’s psychological level and of income effect on one’s socio-demographic level. Our findings indicate that loss aversion and income effect significantly influence the way consumers (...) value food safety vs. quality labels when considering potential health risks and food price. High risk-averse and low-income consumers with strong loss aversion and a weak income effect show a higher demand for food safety labels as a way to ensure easy access to safety indications. Low risk-averse and high-income consumers with weak loss aversion and a strong income effect show a higher demand for food quality labels because they hope to gain more health benefits from high-quality food at good prices. This study provides insights that will assist public authorities and food industry in balancing food safety control and food quality improvement in order to meet the heterogeneous market demand changing alongside the transition of China’s food consumption and production. (shrink)

This essay explores the nature of spontaneous symmetry breaking (SSB) in connection with a cluster of interrelated concepts such as Curie's symmetry principle, ergodicity, and chance and stability in classical systems. First, a clarification of the two existing senses of SSB is provided and an argument developed for a proposal for SSB, in which not only the possibilities but also the actual breakings are referred to. Second, a detailed analysis is given of classical SSB that answers the questions: (i) how (...) we are justified in regarding it as a matter of chance, and (ii) why the breakings in it are equally probable. The answer provides some support to the applicability of ergodicity in special systems (such as ours). (shrink)

Confucianism has usually been regarded as a secular moral philosophy with no religious import at all. In china, However, Confucianism has been mentioned along with buddhism and taoism as one of the three religions (the so-Called san-Chiao) for centuries. This means that we must revise and broaden our traditional concept of religion. The confucian tradition certainly has its unique way of expressing its ultimate and therefore religious concern. The present essay is an attempt to uncover the religious import in confucian (...) philosophy and to ascertain its meaning in contemporary discussions of theology and philosophy of religion. In this article, First, The development of the confucian religious attitude has been traced; second, This attitude has been compared with the christian attitude; third, Its contemporary significance with reference to the current development of theology and religious philosophy in the west has been discussed; finally, Some general remarks upon the relevance of religious message to today's situation have been made. (shrink)

The previous article “Scientific Cosmological Ontology” discussed that the “theoretical contradictions” between quantum mechanics and relativity may become a joke in the history of human existence. It is believed that human philosophical thinking, from Socrates, Plato, to Aristotle, was a turning point. For more than 2000 years, we have been developing in the direction of material philosophy and material science according to Aristotle, and we have reached the peak of human thinking. Modern physics is a great achievement at this peak. (...) According to the principles of dialectical materialism, this “theoretical contradiction” has opened the door to the original thinking of the universe. We have to go back 2500 years to pick up the great banner of cosmic origin that humanity has abandoned, and human thinking. This article continues to analyze the “theoretical contradictions” between quantum mechanics and relativity, and to design the philosophical framework of modern physics according to the thought of cosmic origin. (shrink)

With the arbitrariness of family business decision-making and the complexity of interests become increasingly prominent, the transformation and innovation of family business are imminent. Under the above background, via analysis of data from 259 valid questionnaires from more than ten family businesses in China as a sample and with the help of the SPSS and AMOS, this study explored the impacts of identification on creativity of the family business as well as the mediating role of family business support by constructing (...) a mediating model. The results show that the employee’s identification has a positive impact on the creativity of the family business. Besides, identification has a positive impact on family business support and family business support has a partial mediating role between identification and family business creativity. Especially, the emotional support does not have a mediating role, whereas the instrumental support has a complete mediating role between identification and family business creativity. (shrink)

The COVID-19 pandemic has pressed a pause button on global economic development, and induced significant mental health problems. In order to demonstrate the progressed relationship between the pandemic, economic slowdown, and mental health burden, we overviewed the global-level gross domestic product changes and mental problems variation since the outbreak of COVID-19, and reviewed comprehensively the specific sectors influenced by the pandemic, including international trade, worldwide travel, education system, healthcare system, and individual employment. We hope to provide timely evidence to help (...) with the promotion of policymakers’ effective strategies in mitigating economic losses induced by the pandemic; we suggest different governments or policy makers in different countries to share information and experience in dealing with COVID-19-induced economic slowdown and promote COVID-19 vaccine popularization plan to protect every individual worldwide against the coronavirus essentially; and we appeal international information share and collaboration to minimize stigmatization related to adverse mental consequences of COVID-19 and to increase mental health wellbeings of people all over the world. (shrink)

The relationship between bilingual language control and executive control is debated. The present study investigated the effect of short‐term language switching in a comprehension task on executive control performance in unbalanced bilinguals. Participants were required to perform a context task and an executive control task (i.e., flanker task) in sequence. A picture‐word matching task created different language contexts in Experiment 1 (i.e., L1, L2, and dual‐language contexts). By modifying the color‐shape switching task, we created different contexts that do not involve (...) language processing in Experiment 2 (i.e., color, shape, and dual context). Experiment 1 showed overall faster responses (in both congruent and incongruent trials) in the flanker task after a language switching context than after single (L1 or L2) contexts. This suggests that the language switching in a comprehension task affected general monitoring performance. By contrast, the nonlinguistic contexts in Experiment 2 did not affect flanker performance. This provides further evidence for the crucial role of language processing during switching to elicit short‐term adaptions on domain‐general conflict monitoring. Overall, our findings add to the previous studies by showing cross‐talk between bilingual language control and domain‐general conflict monitoring when language switching occurs in a comprehension task. (shrink)

The research programme of the philosophy of information (PI) proposed in 2002 made it an independent area or discipline in philosophical research. The scientific concept of ‘information’ is formally accepted in philosophical inquiry. Hence a new and tool-driven philosophical discipline of PI with its interdisciplinary nature has been established. Philosophy of information is an ‘orientative’ rather than ‘cognitive’ philosophy. When PI is under consideration in the history of Western philosophy, it can be regarded as a shift of large tradition. There (...) are three large traditions at large, known as Platonic, Kantian and Leibniz-Russellian. In the discussion of the position of the possible worlds, we have modal Platonism and modal realism, but both of the theories are made in the framework of Western philosophy. In this essay, it is argued that possible worlds could be seen as worlds in information, which is then an interpretation of modal information theory (MIT). Our interpretation is made on the basis of Leibniz’s lifelong connection with China, a fact often overlooked by the Western philosophers. Possible world theory was influenced by the Neo-Confucianism flourishing since the Song Dynasty of China, the foundation of which is Yijing. It could be argued that Leibniz’s possible world theory was formulated in respect to the impact of the thoughts reflected in Yijing, in that one of the prominent features is the model-theoretic construction of theories. There are two approaches to theory construction, i.e., axiom-theoretic and model-theoretic. The origin of the former is from ancient Greece and the latter from ancient China. And they determined the different features of theoretic structures between the oriental and occidental traditions of science and technology. The tendency of the future development of science and technology is changing from the axiom-theoretic to the model-theoretic orientation, at least the two approaches being complementary each other. To some extent, this means the retrospective of tradition in the turning point of history, and some of the China’s cultural traditions might become the starting points in formulating the future Chinese philosophy of science and technology. (shrink)

Although the chinese have a heightened sense of time, The concepts of time and temporality developed in their culture are remarkably different from those developed in the west. Certain time-Concepts familiar to the westerners are completely lacking in the chinese tradition. For example, The chinese lacked the concept of absolute time as that held by newton, They also lacked a system to record the years in a linear progressive way, And they seem to have shown a lack of drive to (...) go beyond the realm governed by time and temporality. By deemphasizing the abstract concepts of time, However, They have been able to avoid what whitehead called "the fallacy of misplaced concreteness." the chinese accept their correct destinies as finite beings and work hard in order to find their self-Realization. This explains why they do not view time and death with a sense of anxiety. (shrink)

陆流,字锦川,本号不息,知名中医及气功大师,四川省内外医学、哲学、气功和人体科学等学会理事及委员.

Non‐coding centromeres, which dictate kinetochore formation for proper chromosome segregation, are extremely divergent in DNA sequences across species but are under active transcription carried out by RNA polymerase (RNAP) II. The RNAP II‐mediated centromeric transcription has been shown to facilitate the deposition of the centromere protein A (CENP‐A) to centromeres, establishing a conserved and critical role of centromeric transcription in centromere maintenance. Our recent work revealed another role of centromeric transcription in chromosome segregation: maintaining centromeric cohesion during mitosis. Interestingly, this (...) role appears to be fulfilled through ongoing centromeric transcription rather than centromeric transcripts. In addition, we found that centromeric transcription may not require some of the traditional transcription initiation factors, suggestive of “uniqueness” in its regulation. In this review, we discuss the novel role and regulation of centromeric transcription as well as the potential underlying mechanisms. (shrink)

We examined whether and how managerial ability affects the relationship between customer concentration and corporate performance. Based on a novel measure of managerial ability, we found that customer concentration has a significant negative effect on corporate performance, while managerial ability can mitigate this effect. The negative effect of customer concentration is only significant in the subsample of low ability and lower efficiency in asset utilization, while the moderating effect of managerial ability is significant for all levels of asset utilization efficiency (...) and more significant for firms with a lower gross margin. The results are robust to numerous robustness tests and endogeneity concerns. Additional analysis of mechanisms shows that in addition to superior operating ability, competent managers select major customers who are more beneficial to their company and decrease the sensitivity of their research and development investment to customers. These findings indicate that the heterogeneity of managerial ability plays an important role in the supplier–customer context when the supplier firm generally faces one or more concentrated customers. (shrink)

To improve the personalized service of cultural tourism, anticipatory calculation has become an essential technology in the content design of intelligence navigation system. Culture tourism, as a form of leisure activity, is being favored by an increasing number of people, which calls for further improvements in the cultural consumption experience. An important component of cultural tourism is for tourists to experience intangible cultural heritage projects with local characteristics. However, from the perspective of user needs and the content adaptive system, there (...) are few suitable intelligent navigation and user demand anticipatory systems for intangible cultural heritage content. Purple clay culture is one of the first batches of national intangible cultural heritage protection projects in China. Therefore, taking purple clay culture exhibition as an example, this paper attempts to analyze the personalized information demand of tourism consumption experience in intangible cultural heritage communication activities with affective computing and meaning-driven innovative design method, by taking the content design in the navigation system as the research object. This paper uses the theory of planned behavior to calculate the relationship between tourists’ attitude, experience behavior, and display information demand. The findings indicate two issues. First, tourists’ demand for the entertainment and leisure attributes of intangible cultural heritage is greater than the demand for educational function attributes. Second, the meaning elements of information can change tourists’ beliefs in intangible cultural heritage and affect their attitude and behavior toward such heritage. According to the research results, strengthening the meaning elements of specific group information can improve people’s cultural identity and tourism satisfaction. The research results provide the basis for the content design direction of future museum intelligent navigation systems. (shrink)

This study aimed to investigate the common predictive factors between social media addiction and eating disorder symptoms, in a group of Chinese female college students. A total of 216 students completed the behavioral assessments of cognitive flexibility and sustained attention, as well as the questionnaires on anxiety, social media dependence, and eating disorders. The results indicate that SMA is significantly correlated with EDS. Structural equation modeling was used to test the model in which state anxiety, cognitive flexibility, and sustained attention (...) predicted social gain and EDS. Additionally, the results confirmed the mediating role of cognitive flexibility and sustained attention between state anxiety and SMA/EDS in the participants. The findings revealed that in the sample group, state anxiety was related to SMA and EDS through cognitive flexibility and sustained attention. These proposals reflect the significance of improving cognitive flexibility/sustained attention and reducing state anxiety to prevent EDS and SMA in female college students. (shrink)

The pattern, process, and mechanism of residential heterogeneity vary significantly with different geographical scales. However, most traditional methods ignore the checkboard and modifiable areal unit problem, which may cover up the complexity and hierarchy of social space. Taking Hangzhou city as an example, a multiscalar method was proposed based on the information entropy theory to estimate residential heterogeneity and its scale sensitivity. Based on the sixth population census of Hangzhou and the housing price database of 6,536 residential districts from 2008 (...) to 2018, we explore the scale effect and dynamic characteristics of residential heterogeneity. The results of spatial simulation and geostatistical analysis based on Python Spatial Analysis Library module show that the multiscalar algorithm better presents the real segregation pattern than traditional method, which is one of the new models and technologies in urban geography complex system. Exploring residential heterogeneity through multiscalar lens provides an important basis for the gradual and refined urban renewal. (shrink)

Patients with advanced Alzheimer's disease experience cognitive impairment and physical disabilities in daily life. Currently, there are no treatments available to slow down the course of the disease, and limited treatments exist only to treat symptoms. However, deep brain stimulation of the nucleus basalis of Meynert has been reported to improve cognitive function in individuals with AD. Here, we report the effects of NBM-DBS on cognitive function in a subject with severe AD. An 80-year-old male with severe AD underwent surgery (...) for bilateral NBM-DBS electrode placement. After 10 weeks of stimulation, Mini-Mental State Examination assessment improved from a score of 5 to 9 points, and assessment using the Alzheimer's Disease Assessment Scale–Cognitive Subscale showed a marked reduction in total score from 43 to 33 points, suggesting cognitive benefits from NBM-DBS. The patient's postoperative course was complicated by a subdural effusion that occurred several days after surgery, with complete recovery. Interestingly, the subject also displayed abnormal thermoregulation with stimulation initiation and stimulation parameter modifications. NBM-DBS may serve as a potential therapy for severe AD patients.Clinical Trial Registration: ChiCTR1900022324. (shrink)