This book investigates the role of inference in argumentation, considering how arguments support standpoints on the basis of different loci. The authors propose and illustrate a model for the analysis of the standpoint-argument connection, called Argumentum Model of Topics. A prominent feature of the AMT is that it distinguishes, within each and every single argumentation, between an inferential-procedural component, on which the reasoning process is based; and a material-contextual component, which anchors the argument in the interlocutors’ cultural and factual common (...) ground. The AMT explains how these components differ and how they are intertwined within each single argument. This model is introduced in Part II of the book, following a careful reconstruction of the enormously rich tradition of studies on inference in argumentation, from the antiquity to contemporary authors, without neglecting medieval and post-medieval contributions. The AMT is a contemporary model grounded in a dialogue with such tradition, whose crucial aspects are illuminated in this book. (shrink)

Advancements in novel neurotechnologies, such as brain computer interfaces and neuromodulatory devices such as deep brain stimulators, will have profound implications for society and human rights. While these technologies are improving the diagnosis and treatment of mental and neurological diseases, they can also alter individual agency and estrange those using neurotechnologies from their sense of self, challenging basic notions of what it means to be human. As an international coalition of interdisciplinary scholars and practitioners, we examine these challenges and make (...) recommendations to mitigate negative consequences that could arise from the unregulated development or application of novel neurotechnologies. We explore potential ethical challenges in four key areas: identity and agency, privacy, bias, and enhancement. To address them, we propose democratic and inclusive summits to establish globally-coordinated ethical and societal guidelines for neurotechnology development and application, new measures, including “Neurorights,” for data privacy, security, and consent to empower neurotechnology users’ control over their data, new methods of identifying and preventing bias, and the adoption of public guidelines for safe and equitable distribution of neurotechnological devices. (shrink)

Prevention of age-related disorders is increasingly in focus of health policies, and it is hoped that early intervention on processes of deterioration can promote healthier and longer lives. New opportunities to slow down the aging process are emerging with new fields such as personalized nutrition. Data-intensive research has the potential to improve the precision of existing risk factors, e.g., to replace coarse-grained markers such as blood cholesterol with more detailed multivariate biomarkers. In this paper, we follow an attempt to develop (...) a new aging biomarker. The vision among the project consortium, comprising both research and industrial partners, is that the new biomarker will be predictive of a range of age-related conditions, which may be preventable through personalized nutrition. We combine philosophical analysis and ethnographic fieldwork to explore the possibilities and challenges of managing aging through bodily signs that are not straightforwardly linked to symptomatic disease. We document how the improvement of measurement brings about new conceptual challenges of demarcating healthy and unhealthy states. Moreover, we highlight that the reframing of aging as risk has social and ethical implications, as it is generative of normative notions of what constitutes successful aging and good citizenship. (shrink)

This far-ranging collection of essays represents a conference of the same name held at Emory University in conjunction with a meeting of the “Rethinking Plato’s Parmenides” seminar sponsored by the Society of Biblical Literature.In embracing authors as diverse as Plato himself, Epictetus, Ralph Cudworth, Yeats, and Levinas, to name a few of the Platonists identified herein, the volume clearly and deliberately stretches the meaning of this rubric to its outer limits. This review will reprise some of the articles from each (...) of the book’s sections—Ancient, Late Antique, Renaissance and Modern, and Post-modern Platonisms—in an effort to help readers gauge the argument of the book, which may or may not be endorsed by each of the individual contributors. The editors, at least in compiling this anthology, do so in the belief that Platonism might better be considered “as an inexhaustible mine of possible trajectories each of which helps us to see the richness of Platonic texts,” rather than “as a series of determinate doctrines” .Thomas Slezak opens the volume with a rehearsal of his programmatic way of reading Plato’s dialogues, involving two possibly competing claims: what Plato means by philosophy is not contained within the. (shrink)

Many philosophers hypothesize that our concept of personal identity is partly constituted by the one-person-one-place rule, which states that a person can only be in one place at a time. This hypothesis has been assumed by the most influential contemporary work on personal identity. In this paper, we report a series of studies testing whether the hypothesis is true. In these studies, people consistently judged that the same person existed in two different places at the same time. This result undermines (...) some widely held philosophical assumptions, supports others, and fits well with recent discoveries on identity judgments about inanimate objects and non-human animals. (shrink)

Free will, if such there be, involves free choosing: the ability to mentally choose an outcome, where the outcome is 'free' in being, in some substantive sense, up to the agent of the choice. As such, it is clear that the questions of how to understand free will and mental causation are connected, for events of seemingly free choosing are mental events that appear to be efficacious vis-a-vis other mental events as well as physical events. Nonetheless, the free will and (...) mental causation debates have proceeded largely independently of each other. Here we aim to make progress in determining how the free will and mental causation debates bear on one another. We first argue that the problems of free will and of mental causation can be seen as special cases of a more general problem, concerning whether and how mental events of a given type may be efficacious, qua the types of event they are---qualitative, intentional, freely deliberative---given their apparent causal irrelevancy for effects of the type in question; here we generalize what Horgan 1989 identifies as "the problem of mental quausation" (S1). We then build on this result to identify fruitful parallels between hard determinism and eliminative physicalism (S2) and soft determinism and non-reductive physicalism (S3). (shrink)

This paper argues that scale-dependence of physical and biological processes offers resistance to reductionism and has implications that support a specific kind of downward causation. I demonstrate how insights from multiscale modeling can provide a concrete mathematical interpretation of downward causation as boundary conditions for models used to represent processes at lower scales. The autonomy and role of macroscale parameters and higher-level constraints are illustrated through examples of multiscale modeling in physics, developmental biology, and systems biology. Drawing on these examples, (...) I defend the explanatory importance of constraining relations for understanding the behavior of biological systems. (shrink)

This book tackles the most difficult and profound open questions about life and its origins from an information-based perspective.

We appreciate Chapman and colleagues’ (2025) advocacy for revising the Common Rule to address the downstream effects of data-centric research, particularly the potential for group harms such as sti...

Philosophers who have written on modesty have largely agreed that it is a virtue, and that it therefore has an important psychological component. Mere modest behavior, it is often argued, is actually false modesty if it is generated by the wrong kind of mental state. The philosophical debate about modesty has largely focused on the question of which kind of mental state—cognitive, motivational, or evaluative—best captures the virtue of modesty. We therefore conducted a series of experiments to see which philosophical (...) account matches the folk concept of modesty. Surprisingly, we found that the folk concept is primarily behavioral. This leads us to argue that modesty may not be a virtue, but that if it is none of the extant philosophical accounts have properly explained why. (shrink)

Bioethics has already had a rich interaction with the relatively new field of neurotechnology. Scholars have wondered whether neurotechnological interventions, such as deep brain stimulation, are threats to personal identity, lead to alienation or create dilemmas between authenticity and autonomy, impact autonomy, detract from agency, or lead to self-estrangement. Many of these ethical investigations are concerned not with the targeted health benefits of neurotechnology but with whether and how they fit into users' lives in more personal and profound ways.In some (...) ways, this focus on general bioethical issues... (shrink)

In Democracy without Shortcuts, Cristina Lafont identifies proceduralist or ‘deep pluralist’ conceptions of democracy alongside epistemic and lottocratic approaches as shortcuts that avoid the more challenging but, in her view, preferable path of engaging with and attempting to sway competing views, values and beliefs of fellow citizens. I argue that with the wholesale dismissal of proceduralist accounts of democracy Lafont herself takes two shortcuts: The first concerns the characterization of deep pluralism as unable to explain substantive disagreement after a decision (...) is settled, and the second undervalues proceduralism’s ability to evaluate and criticize the substance of the political decision-making process. While her critique is fitting for minimalist conceptions of proceduralism, a theory of normative proceduralism shares many objectives with Lafont’s vision of a participatory deliberative democracy. Integrating those approaches instead of dismissing proceduralism outright would render her project appealing to theorists who would not otherwise consider themselves deliberative democrats. (shrink)

Employers and governments are interested in the use of serological testing to allow people to return to work before there is a vaccine for SARS-CoV-2. We articulate the preconditions needed for the implementation of antibody testing, including the role of the U.S. Food & Drug Administration.

Implanted medical devices—for example, cardiac defibrillators, deep brain stimulators, and insulin pumps—offer users the possibility of regaining some control over an increasingly unruly body, the opportunity to become part “cyborg” in service of addressing pressing health needs. We recognize the value and effectiveness of such devices, but call attention to what may be less clear to potential users—that their vulnerabilities may not entirely disappear but instead shift. We explore the kinds of shifting vulnerabilities experienced by people with Parkinson’s disease (PD) (...) who receive therapeutic deep brain stimulators to help control their tremors and other symptoms of PD. (shrink)

Philosophical writing is challenging for students new to philosophy. Many philosophy classes are populated, for the most part, by students who have never taken philosophy before. While many institutions offer general writing support services, these services tend to be most beneficial for helping to identify problems with style and grammar. They are not equipped to help students with the particular challenges that come with writing philosophy for the first time. We implemented the “Home Base” Mentoring Program in two introductory level (...) philosophy courses to target the specific challenges that novice learners have when learning how to write philosophy. Through the program, students had access to writing mentors who were undergraduate senior philosophy majors. Based on surveys given to the students who have participated in this program, we found that the program boosted student confidence in writing and also worked to develop a welcoming, judgment-free, and encouraging environment in the philosophy department more generally. (shrink)

The biological sciences provide ample opportunity and motivation for feminist interventions. These sciences are seen by many as an authority on human nature and are highly relevant to many issues of social justice and public policy. Feminist philosophy of biology focuses on the ethical and epistemic adequacy and responsibility of biological claims. This work is critical in the sense of identifying epistemically and ethically irresponsible knowledge claims, research practices, and dissemination of biological research regarding sex/gender, including ways that sex/gender interacts (...) with other social categories. In this chapter we describe classic themes in feminist philosophy of biology, with particular regard to research practices and metaphysical assumptions. We then go on to argue that these classic themes remain salient in contemporary neuroscientific investigations of human emotion and in feminist research on the evolution of human behavior. (shrink)

The politics of populism is the politics of belonging. It reflects a deep challenge to the liberal democratic state, which attempts to maintain social boundaries (as an imperative of state capacity) but also allow immigration. Boundaries—established through citizenship and norms of belonging—must be both coherent and malleable. Changes to boundaries become sites of contestation for exclusionary populists in the putative interest of “legitimate” citizens. Populism is an inevitable response to liberal democratic adjustment; any liberal democracy that redefines citizenship opens itself (...) to populist challenge. (shrink)

Research on dyscalculia in neurodegenerative diseases is still scarce, despite high impact on patients’ independence and activities of daily living function. Most studies address Alzheimer’s Disease; however, patients with Parkinson’s Disease also have a higher risk for cognitive impairment while the relation to arithmetic deficits in financial contexts has rarely been studied. Therefore, the current exploratory study investigates deficits in two simple arithmetic tasks in financial contexts administered within the Clinical Dementia Rating in a sample of 100 PD patients. Patients (...) were classified as cognitively normal or mildly impaired according to Level I consensus criteria, and assessed using a comprehensive neuropsychological test battery, neurological motor examination, and sociodemographic and clinical questionnaires. In total, 18% showed arithmetic deficits: they were predominately female, had longer disease duration, more impaired global cognition, but minor signs of depression compared to PD patients without arithmetic deficits. When correcting for clinical and sociodemographic confounders, greater impairments in attention and visuo-spatial/constructional domains predicted occurrence of arithmetic deficits. The type of deficit did not seem to be arbitrary but seemed to involve impaired place × value processing frequently. Our results argue for the importance of further systematic investigations of arithmetic deficits in PD with sensitive tests to confirm the results of our exploratory study that a specific subgroup of PD patients present themselves with dyscalculia. (shrink)

The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology? To what extent is the use of mathematical and computational modelling changing the life sciences? How does the availability of big data influence research practices? What are the major challenges for biomedical research in the years to come? This book addresses such questions of relevance not only to philosophers and biologists but also to readers interested in the broader (...) implications of systems biology for science and society. The book features reflections and original work by experts from across the disciplines including systems biologists, philosophers, and interdisciplinary scholars investigating the social and educational aspects of systems biology. In response to the same set of questions, the experts develop and defend their personal perspectives on the distinctive character of systems biology and the challenges that lie ahead. Readers are invited to engage with different views on the questions addressed, and may explore numerous themes relating to the philosophy of systems biology. This edited work will appeal to scholars and all levels, from undergraduates to researchers, and to those interested in a variety of scholarly approaches such as systems biology, mathematical and computational modelling, cell and molecular biology, genomics, systems theory, and of course, philosophy of biology. (shrink)

Why do some parents refuse to vaccinate their children? Why do some people keep guns at home, despite scientific evidence of risk to their family members? And why do people use antibiotics for illnesses they cannot possibly alleviate? When it comes to health, many people insist that science is wrong, that the evidence is incomplete, and that unidentified hazards lurk everywhere. In Denying to the Grave, Gorman and Gorman, a father-daughter team, explore the psychology of health science denial. Using several (...) examples of such denial as test cases, they propose six key principles that may lead individuals to reject "accepted" health-related wisdom: the charismatic leader; fear of complexity; confirmation bias and the internet; fear of corporate and government conspiracies; causality and filling the ignorance gap; and the nature of risk prediction. The authors argue that the health sciences are especially vulnerable to our innate resistance to integrate new concepts with pre-existing beliefs. This psychological difficulty of incorporating new information is on the cutting edge of neuroscience research, as scientists continue to identify brain responses to new information that reveal deep-seated, innate discomfort with changing our minds. Denying to the Grave explores risk theory and how people make decisions about what is best for them and their loved ones, in an effort to better understand how people think when faced with significant health decisions. This book points the way to a new and important understanding of how science should be conveyed to the public in order to save lives with existing knowledge and technology. (shrink)

Professor d’Hoine claims that Proclus assigns a specific ontological function to the Form of Likeness in his Commentary on the Parmenides. According to d’Hoine, for Proclus, each individual must, qua individual striving to imitate the form, present a difference; this difference or unlikeness of one member of a coordinate kind to another, the plurality of participants in a Form, is Form’s by the Form of Unlikeness. And in a similar way, the Form of Likeness then guarantees the imitation of the (...) Form by the particular. I try to show that in other passages in Proclus’ oeuvre, likeness extends to include many more relationships than the Forms instantiation as a material particular. Hence, Likeness is not confined to this specific ontological function. (shrink)

Volume 25, Issue 3, March 2025, Page 115-118.

Perspective taking has been proposed to be impaired in persons with autism spectrum disorder, especially when implicit processing is required. In narrative texts, language perception and interpretation is fundamentally guided by taking the perspective of a narrator. We studied perspective taking in the linguistic domain of so-called Free Indirect Discourse, during which certain text segments have to be interpreted as the thoughts or utterances of a protagonist without explicitly being marked as thought or speech representations of that protagonist. Crucially, the (...) correct interpretation of text segments as FID depends on the ability to detect which of the protagonists “stands out” against the others and is therefore identifiable as implicit thinker or speaker. This so-called “prominence” status of a protagonist is based on linguistic properties, in other words, the perspective is “hidden” and has to be inferred from the text material. In order to test whether this implicit perspective taking ability that is required for the interpretation of FID is preserved in persons with ASD, we presented short texts with three sentences to adults with and without ASD. In the last sentence, the perspective was switched either to the more or the less prominent of two protagonists. Participants were asked to rate the texts regarding their naturalness. Both diagnostic groups rated sentences with FID anchored to the less prominent protagonist as less natural than sentences with FID anchored to the more prominent protagonist. Our results that the high-level perspective taking ability in written language that is required for the interpretation of FID is well preserved in persons with ASD supports the conclusion that language skills are highly elaborated in ASD so that even the challenging attribution of utterances to protagonists is possible if they are only implicitly given. We discuss the implications in the context of claims of impaired perspective taking in ASD as well as with regard to the underlying processing of FID. (shrink)

Proponents of the emerging field of P4 medicine argue that computational integration and analysis of patient-specific “big data” will revolutionize our health care systems, in particular primary care-based disease prevention. While many ambitions remain visionary, steps to personalize medicine are already taken via personalized genomics, mobile health technologies and pilot projects. An important aim of P4 medicine is to enable disease prevention among healthy persons through detection of risk factors. In this paper, we examine the current status of P4 medicine (...) in light of historical and current challenges to predictive and preventive medicine, including overdiagnosis and overtreatment. Moreover, we ask whether it is likely that in silico integration of patient-specific data will be able to better deal such challenges and to turn risk predictions into disease-preventive actions in a wider social context. Given the lack of evidence that P4 medicine can tip the balance between benefits and harms in preventive medicine, we raise concerns about the current promotion of P4 medicine as a solution to the current challenges in public health. (shrink)

In recent years, and in the current climate crisis, the interest in veganism and sustainable diet/lifestyle has increased. This growing interest can also be seen within academia. Therefore, we set out to systematically document and organize the social psychological literature on veganism and vegan identity to identify where the field currently is, and what we need to do next. Following PRISMA guidelines we identified a data set of 26 academic papers published between 2010 and 2021. Through a thematic analysis of (...) the data, we created four categories of study focus and content: vegans as a disadvantaged/stigmatized group, the role of ideology in negative attitudes toward vegans, the role of moral and ethical beliefs in changing or sustaining dietary preferences, and veganism as a social movement and vegan activism. Our analysis emphasizes issues with merging all non-meat eaters, reduction of veganism into dietary or lifestyle choices neglecting the politicized content and movement, lack of processes underlying emergence and endurance of veganism, and decontextualization of vegan identity. What is needed is a more fine-grained exploration that addresses the identified issues to account for the content of vegan identity. This would expand, for example, the motives literature to include and emphasize intersectionality in a vegan identity context. Specifically, to facilitate a more sustainable lifestyle, the content of social dimensions needs to be qualitatively explored. (shrink)

Due to the variation, contingency and complexity of living systems, biology is often taken to be a science without fundamental theories, laws or general principles. I revisit this question in light of the quest for design principles in systems biology and show that different views can be reconciled if we distinguish between different types of generality. The philosophical literature has primarily focused on generality of specific models or explanations, or on the heuristic role of abstraction. This paper takes a different (...) approach in emphasizing a theory-constituting role of general principles. Design principles signify general dependencyrelations between structures and functions, given a set of formally defined constraints. I contend that design principles increase our understanding of living systems by relating specific models to general types. The categorization of types is based on a delineation of the scope of biological possibilities, which serves to identify and define the generic features of classes of systems. To characterize the basis for general principles through generic abstraction and reasoning about possibility spaces, I coin the term constraint-based generality. I show that constraintbased generality is distinct from other types of generality in biology, and argue that general principles play a unifying role that does not entail theory reduction. (shrink)

Para la década de 1990 el paradigma del archivo vinculó los problemas de la serialidad y lo cotidiano con la memoria y el arte empezó a relacionarse con las construcciones sobre el pasado. Un arte que emerge en contra de la amnesia, el olvido y la creciente despolitización de la sociedad, lo que implica que ante estas obras los espectadores se muevan críticamente, se apropien de las construcciones plásticas sobre lo que nos ha sucedido y cuestionen la historia tradicional. En (...) esta lógica se encuentran algunos de los trabajos de Jorge Marín, de la que se destaca su serie Sobre héroes y monumentos (2019), en la que el artista, por hacer uso de la memoria visual nacional, cuestiona y actualiza la imagen de los próceres y subvierte la visión decimonónica y hegemónica de nuestro pasado. El objetivo de este texto es brindar herramientas para entender cómo, desde el arte, se pone en entredicho la epopeya libertadora como mito fundacional del Estado-Nación actual a través de la perturbación del patrimonio iconográfico colombiano. Lo relevante de este caso es que Marín crea significado cuando acude al uso del archivo con el fin de manipular y simular las imágenes sobre la historia nacional y, por eso, se hace necesaria una reflexión que parta de la teoría y la filosofía de la historia, con autores como Danto y Marchán Fiz, para construir ideas significativas en torno al arte que usa el paradigma del archivo (Guasch) y se posiciona como apuesta política y crítica (Vilar, Rancière, Mouffe). (shrink)

When police officers interview people with intellectual disabilities who allege sexual assault and rape, they must establish rapport with the interviewee but deal with their distress in a way that does not compromise the interview’s impartiality and its acceptability in court. Inspection of 19 videotaped interviews from an English police force’s records reveals that the officers deal with expressed distress by choosing among three practices: minimal or no acknowledgement, acknowledging the expressed emotion as a matter of the complainant’s difficulty in (...) proceeding and rarely explicit reference to their emotion. We discuss these practices as ways of managing the conflicting demands of rapport and evidence-gathering. (shrink)

Este artículo presenta una investigación cualitativa sobre los conceptos de Hermenéutica e ironía desde la revisión del texto rortiano Contingencia, ironía y solidaridad. A través de un recorrido por la Historia de la razón filosófica se muestra cómo el compromiso hermenéutico con el mundo está atravesado por las ideas de solidaridad y contingencia. Finalmente, se propone una lectura del círculo hermenéutico como reivindicación de una sociedad preocupada por la justicia que reconoce la carencia de todo amparo metafísico.

In lieu of an abstract, here is a brief excerpt of the content:Athenian Democratic Ideology and Herodotus' HistoriesSara ForsdykeIt is an oft-repeated refrain in studies of Athenian politics that we have no ancient treatises that systematically describe Athenian beliefs about the value of democracy.1 Although we can reconstruct some democratic values from the institutions and practices of the Athenian state, scholars have had to rely on elite writers such as Thucydides, Plato, and Aristotle, or on the more allusive references in (...) Athenian drama in order to get at the positive tenets of democratic political theory. Recently, oratory has been shown to be a valuable source for democratic political values. Great progress has been made in elucidating Athenian political thought and ideology from all these sources.2In this article, I wish to point to a rather neglected source for Athenian democratic ideology, namely Herodotus' Histories. While parts of the Histories (especially the constitutional debate) have been studied for Greek political thought, less has been made of the Histories as a source for Athenian democratic political beliefs.3 I argue that democratic [End Page 329] political values form the background against which several of Herodotus' narratives resonate and that thus these narratives may provide fruitful ground from which to extract some central themes, symbols, and ideas of Athenian democratic ideology.Herodotus' narratives dealing with Athens are the obvious place to look for signs of Athenian political values, since they ultimately derive from Athenian sources. Yet full utilization of these narratives as a source for democratic beliefs has been hampered by the view, argued by Jacoby and accepted by many current historians, that Herodotus relied primarily on the aristocratic family traditions of the Alcmeonidae for his Athenian narratives and hence that his narratives do not reflect the beliefs of the Athenians as a whole but only those of a particular aristocratic family.4 [End Page 330]This view has been challenged, most recently by Rosalind Thomas in her pathbreaking study of the nature of oral traditions in archaic and classical Greece. Thomas argues that Herodotus' Histories, and in particular his account of the liberation of Athens from the Peisistratid tyranny, reflects a wide variety of traditions, including popular or polis traditions as well as family ones. Certain elements of Herodotus' account, she argues, are decidedly unflattering to the family of the Alcmeonidae and can only be explained by Herodotus' utilization of non Alcmeonid and, in particular, wider polis traditions.5Thomas's revisions of the dominant view of Herodotus' versions of Athenian history open the way for a new evaluation of Herodotus' narratives as a source for polis traditions, or widespread Athenian beliefs about their history and the origins and nature of their political system.6 Furthermore, since these polis traditions were orally transmitted, and oral traditions are shaped by the values of the group that transmits them, they should reveal the values of the fifth-century Athenians from whom Herodotus heard them.7 Herodotus' narratives about early Athenian history, therefore, can be used as a source for widespread, fifth-century Athenian political beliefs and values, as well as partisan family traditions.8In the first part of this article, I argue that comparison of Herodotus' use of the verb in his Athenian narratives with the occurrence of this word in Athenian dramatic and historical texts reveals that this was a key term in the Athenians' understanding of the value of democracy. Specifically, I argue that the word was used by the Athenians to describe the forceful subjection of a people by a tyrant and was associated with Athenian ideas about the weakness of societies ruled by [End Page 331] a tyrant in contrast to the strength of free societies with a democratic political system. In the second half of this article, I argue that the theme of tyranny/civic weakness versus democracy/civic strength underlies Herodotus' presentation of some non-Athenian narratives. In particular, I argue that structural and thematic parallels between the conversation between Xerxes and Demaratus in the Histories and the conversation between Atossa and her messenger in Aeschylus' Persians reveal that the contrast between tyranny and freedom in the Demaratus episode is derived from Athenian democratic ideology.Athenian Democratic Ideology in Herodotus' Athenian NarrativesHerodotus' first... (shrink)