Different types of consent are used to obtain human biospecimens for future research. This variation has resulted in confusion regarding what research is permitted, inadvertent constraints on future research, and research proceeding without consent. The National Institutes of Health Clinical Center's Department of Bioethics held a workshop to consider the ethical acceptability of addressing these concerns by using broad consent for future research on stored biospecimens. Multiple bioethics scholars, who have written on these issues, discussed the reasons for consent, the (...) range of consent strategies, and gaps in our understanding, and concluded with a proposal for broad initial consent coupled with oversight and, when feasible, ongoing provision of information to donors. This article describes areas of agreement and areas that need more research and dialogue. Given recent proposed changes to the Common Rule, and new guidance regarding storing and sharing data and samples, this is an important and tim.. (shrink)

Controversy persists over the ethics of compensating research participants and providing posttrial benefits to communities in developing countries. Little is known about residents' views on these subjects. In this study, interviews about compensation and posttrial benefits from a hypothetical HIV vaccine trial were conducted in Uganda’s Rakai District. Most respondents said researchers owed the community posttrial benefits and research compensation, but opinions differed as to what these should be. Debates about posttrial benefits and compensation rarely include residents' views like these, (...) but future ones should. (shrink)

Although informed consent is important in clinical research, questions persist regarding when it is necessary, what it requires, and how it should be obtained. The standard view in research ethics is that the function of informed consent is to respect individual autonomy. However, consent processes are multidimensional and serve other ethical functions as well. These functions deserve particular attention when barriers to consent exist. We argue that consent serves seven ethically important and conceptually distinct functions. The first four functions pertain (...) principally to individual participants: (1) providing transparency; (2) allowing control and authorization; (3) promoting concordance with participants' values; and (4) protecting and promoting welfare interests. Three other functions are systemic or policy focused: (5) promoting trust; (6) satisfying regulatory requirements; and (7) promoting integrity in research. Reframing consent around these functions can guide approaches to consent that are context sensitive and that maximize achievable goals. (shrink)

California is a landmark setting for studying produce recovery efforts and policy implications because of its global relevance in agricultural production, its complex network of food recovery organizations, and its environmental and public health regulations. Through a series of focus groups with organizations involved in produce recovery (gleaning organizations) and emergency food operations (food banks, food pantries), this study aimed to deepen our understanding of the current produce recovery system and determine the major challenges and opportunities related to the produce (...) recovery system. Operational and systematic barriers to produce recovery were highlighted by both gleaning and emergency food operations. Operational barriers, such as the lack of appropriate infrastructure and limited logistical support were found to be a challenge across groups and were directly tied to inadequate funding for these organizations. Systematic barriers, such as regulations related to food safety or reducing food loss and waste, were also found to impact both gleaning and emergency food organizations, but differences were observed in how each type of regulation impacted each stakeholder group. To support the expansion of food recovery efforts, participants expressed need for better coordination within and across food recovery networks and more positive and transparent engagement from regulators to increase understanding of the specifics of their unique operational constraints. The focus group participants also provided critiques on how emergency food assistance and food recovery are inscribed within the current food system and for longer term goals of reducing food insecurity and food loss and waste a systematic change will be required. (shrink)

Neo-teleology is the two part thesis that, e.g., (i) we have hearts because of what hearts are for: Hearts are for blood circulation, not the production of a pulse, so hearts are there--animals have them--because their function is to circulate the blood, and (ii) that (i) is explained by natural selection: traits spread through populations because of their functions. This paper attacks this popular doctrine. The presence of a biological trait or structure is not explained by appeal to its function. (...) To suppose otherwise is to trivialize natural selection. (shrink)

Natural selection is commonly interpreted as the fundamental mechanism of evolution. Questions about how selection theory can claim to be the all-sufficient explanation of evolution often go unanswered by today's neo-Darwinists, perhaps for fear that any criticism of the evolutionary paradigm will encourage creationists and proponents of intelligent design.In Biological Emergences, Robert Reid argues that natural selection is not the cause of evolution. He writes that the causes of variations, which he refers to as natural experiments, are independent of (...) natural selection; indeed, he suggests, natural selection may get in the way of evolution. Reid proposes an alternative theory to explain how emergent novelties are generated and under what conditions they can overcome the resistance of natural selection. He suggests that what causes innovative variation causes evolution, and that these phenomena are environmental as well as organismal.After an extended critique of selectionism, Reid constructs an emergence theory of evolution, first examining the evidence in three causal arenas of emergent evolution: symbiosis/association, evolutionary physiology/behavior, and developmental evolution. Based on this evidence of causation, he proposes some working hypotheses, examining mechanisms and processes common to all three arenas, and arrives at a theoretical framework that accounts for generative mechanisms and emergent qualities. Without selectionism, Reid argues, evolutionary innovation can more easily be integrated into a general thesis. Finally, Reid proposes a biological synthesis of rapid emergent evolutionary phases and the prolonged, dynamically stable, non-evolutionary phases imposed by natural selection. (shrink)

Recent debates over adults' theory of mind use have been fueled by surprising failures of perspective-taking in communication, suggesting that perspective-taking may be relatively effortful. Yet adults routinely engage in effortful processes when needed. How, then, should speakers and listeners allocate their resources to achieve successful communication? We begin with the observation that the shared goal of communication induces a natural division of labor: The resources one agent chooses to allocate toward perspective-taking should depend on their expectations about the other's (...) allocation. We formalize this idea in a resource-rational model augmenting recent probabilistic weighting accounts with a mechanism for (costly) control over the degree of perspective-taking. In a series of simulations, we first derive an intermediate degree of perspective weighting as an optimal trade-off between expected costs and benefits of perspective-taking. We then present two behavioral experiments testing novel predictions of our model. In Experiment 1, we manipulated the presence or absence of occlusions in a director–matcher task. We found that speakers spontaneously modulated the informativeness of their descriptions to account for “known unknowns” in their partner's private view, reflecting a higher degree of speaker perspective-taking than previously acknowledged. In Experiment 2, we then compared the scripted utterances used by confederates in prior work with those produced in interactions with unscripted directors. We found that confederates were systematically less informative than listeners would initially expect given the presence of occlusions, but listeners used violations to adaptively make fewer errors over time. Taken together, our work suggests that people are not simply “mindblind”; they use contextually appropriate expectations to navigate the division of labor with their partner. We discuss how a resource-rational framework may provide a more deeply explanatory foundation for understanding flexible perspective-taking under processing constraints. (shrink)

Author Robert Wright shows how Buddhist meditative practice can loosen the grip of anxiety, regret, and hatred, and deepen your appreciation of beauty and other people." -- Adapted from book jacket.

Mesoscale modeling is often considered merely as a practical strategy used when information on lower-scale details is lacking, or when there is a need to make models cognitively or computationally tractable. Without dismissing the importance of practical constraints for modeling choices, we argue that mesoscale models should not just be considered as abbreviations or placeholders for more “complete” models. Because many systems exhibit different behaviors at various spatial and temporal scales, bottom-up approaches are almost always doomed to fail. Mesoscale models (...) capture aspects of multi-scale systems that cannot be parameterized by simple averaging of lower-scale details. To understand the behavior of multi-scale systems, it is essential to identify mesoscale parameters that “code for” lower-scale details in a way that relate phenomena intermediate between microscopic and macroscopic features. We illustrate this point using examples of modeling of multi-scale systems in materials science and biology, where identification of material parameters such as stiffness or strain is a central step. The examples illustrate important aspects of a so-called “middle-out” modeling strategy. Rather than attempting to model the system bottom-up, one starts at intermediate scales where systems exhibit behaviors distinct from those at the atomic and continuum scales. One then seeks to upscale and downscale to gain a more complete understanding of the multi-scale system. The cases highlight how parameterization of lower-scale details not only enables tractable modeling but is also central to understanding functional and organizational features of multi-scale systems. (shrink)

Group beneficial norms are common in human societies. The persistence of such norms is consistent with evolutionary game theory, but existing models do not provide a plausible explanation for why they are common. We show that when a model of imitation used to derive replicator dynamics in isolated populations is generalized to allow for population structure, group beneficial norms can spread rapidly under plausible conditions. We also show that this mechanism allows recombination of different group beneficial norms arising in..

Hegel's holistic metaphysics challenges much recent ontology with its atomistic and reductionist assumptions; Stern offers us an original reading of Hegel and contrasts him with his predecessor, Kant.

Selected by CHOICE as an Outstanding Academic Book for 1995.

Complexity–nonlinear dynamics for my purposes in this essay–is rich with metaphysical and epistemological implications but is only recently receiving sustained philosophical analysis. I will explore some of the subtleties of causation and constraint in Rayleigh-Bénard convection as an example of a complex phenomenon, and extract some lessons for further philosophical reflection on top-down constraint and causation particularly with respect to causal foundationalism.

It is often held that to have a conscious experience presupposes having some form of implicit self-awareness. The most dominant phenomenological view usually claims that we essentially perceive experiences as our own. This is the so called “mineness” character, or dimension of experience. According to this view, mineness is not only essential to conscious experience, it also grounds the idea that pre-reflective self-awareness constitutes a minimal self. In this paper, we show that there are reasons to doubt this constituting role (...) of mineness. We argue that there are alternative possibilities and that the necessity for an adequate theory of the self within psychopathology gives us good reasons to believe that we need a thicker notion of the pre-reflective self. To this end, we develop such a notion: the Pre-Reflective Situational Self. To do so, we will first show how alternative conceptions of pre-reflective self-awareness point to philosophical problems with the standard phenomenological view. We claim that this is mainly due to fact that within the phenomenological account the mineness aspect is implicitly playing several roles. Consequently, we argue that a thin interpretation of pre-reflective self-awareness—based on a thin notion of mineness—cannot do its needed job within, at least within psychopathology. This leads us to believe that a thicker conception of pre-reflective self is needed. We, therefore, develop the notion of the pre-reflective situational self by analyzing the dynamical nature of the relation between self-awareness and the world, specifically through our interactive inhabitation of the social world. (shrink)

Understanding cooperation and punishment in small-scale societies is crucial for explaining the origins of human cooperation. We studied warfare among the Turkana, a politically uncentralized, egalitarian, nomadic pastoral society in East Africa. Based on a representative sample of 88 recent raids, we show that the Turkana sustain costly cooperation in combat at a remarkably large scale, at least in part, through punishment of free-riders. Raiding parties comprised several hundred warriors and participants are not kin or day-to-day interactants. Warriors incur substantial (...) risk of death and produce collective benefits. Cowardice and desertions occur. (shrink)

Rice, Robert James William Gleeson was born in Balaklava, a town in the mid-north of South Australia, on 24 December 1920. The son of John Joseph Gleeson and Margaret Mary O'Connell, he was the third born of six children - the elder brother of Thomas, John and Raphael (Ray), and the younger brother of Mary. The first-born child, also Mary, born in Balaklava on 6 May 1918, died one hour after birth. She was baptised during her short life.

The first five chapters of the second book of Aristotle's Politics contain a series of criticisms levelled against Plato's Republic. Despite the abundance of studies that have been done on Aristotle's Politics, these chapters have for the most part been neglected; there has been no book-length study of them this century. In this important new book, Robert Mayhew fills this unfortunate gap in Aristotelian scholarship, analyzing these chapters in order to discover what they tell us about Aristotle's political philosophy. (...) Mayhew demonstrates that in Politics II 1-5, Aristotle is presenting his views on an extremely fundamental issue: the unity of the city. Indeed, he states, almost all of Aristotle's criticisms of the Republic center on this important subject in one way or another. Only by understanding Aristotle's views on the proper unity of the city, Mayhew explains, can we adequately discover his views on the proper relationship between the individual and the city. Students and scholars of classical political philosophy will be greatly interested in this innovative book. (shrink)

In this accessible and comprehensive work, Robert Solomon and Kathleen Higgins cover the entire history of philosophy--ancient, medieval, and modern, from cultures both East and West--in its broader historical and cultural contexts. Major philosophers and movements are discussed along with less well-known but interesting figures. The authors examine the early Greek, Indic, and Chinese philosophers and the mythological traditions that preceded them, as well as the great religious philosophies, including Christianity, Hinduism, Judaism, and Taoism. Easily understandable to students without (...) specialized knowledge of philosophy, A Short History of Philosophy demonstrates the relevance of philosophy to our times, illuminating the impact of the revolutions wrought by science, industry, colonialism, and sectarian warfare; the two world wars and the Holocaust; and the responses of philosophy in the schools of existentialism, postmodernism, feminism, and multiculturalism. In addition, the authors provide their own twists and interpretations of events, resulting in a broad view of the nature of philosophy as an intellectual discipline and its sometimes odd and dramatic consequences. (shrink)

We compare Gödel’s and Brouwer’s explorations of mysticism and its relation to mathematics.

Normative naturalism (NN), advocated by Larry Laudan, understands the principles of scientific method to be akin to scientific hypotheses which are then open to test like any principles of science. It uses a meta-inductive rule to test methodological principles against suitably presented episodes in the history of science. One strength of NN is that it provides the basis for a philosophical/historical research programme into the methodological strategies actually employed in the sciences. But for the philosopher interested in the grounds of (...) scientific rationality NN is not without it difficulties such as: it adopts a strongly empiricist account of meta-method which rules out realist principles of scientific method from the test procedures; it uses principles of test which are either not agreed upon, or stray from the meta-inductive rule; it reveals its limits in presupposing answers, rather than offering solutions, to problems of scientific rationality. (shrink)

Uses textual and archaeological evidence to argue that emerging Egyptian and Greek architectural technologies were crucial to the origins and development of Greek philosophy.

This volume collects thirteen papers by Robert Audi on action theory, all but two previously published, and dating back as far as the early 1970s. The reader should not be misled by the book's publicity, which proclaims that we are being given "for the first time... a full version of his [Audi's] theory of... human action". Despite such claims, this volume is no more than a collection of papers, and consequently it does not offer the depth and continuity one (...) would expect from a book-length treatment. Still, this is a collection of very fine papers, and collectively they constitute an important and influential theory of action. (shrink)

Mourir pour la France, faire la guerre, tomber au champ d'honneur... Les jeunes générations y songent-elles encore? Il est vrai que la désacralisation de la chose militaire, propagée par l'hédonisme-pacifisme triomphant, a eu raison de cette aspiration traditionnelle. Le 14juillet des dernières décennies n'est-il pas devenu une fête pour la fête parmi tant d'autres, où les défilés militaires s'exposent au regard comme un spectacle de foire? L'Ecole a, elle-même, renoncé à exalter les vertus de la nation et de la patrie (...) tant glorifiées par la Révolution. Cette mise au ban du soldat comme de l'Histoire ne traduit-elle pas un déni de réalité caractérisé? Comme s'il suffisait de fermer les yeux sur les multiples motifs d'hostilité entre les Etats pour en neutraliser la bête noire : l'éternel retour de la guerre et de ses innombrables morts que l'esprit victimaire d'aujourd'hui récupère insidieusement. C'est oublier que la France ne serait pas la France sans ces guerres qui ont fait date, sans un choix décisif de société, sans un refus de se soumettre à la loi de l'Occupant. Bref, sans une certaine idée de la France... Les figures d'épouvantail successives sous lesquelles disparaît désormais le soldat - gendarme, bourreau, nazi, etc., - achèvent de brouiller le sens profond de son sacrifice. Où la part de sang versé et répandu, renforçant le lien de l'individu à la Nation, révèle aussi la part inconnue, transcendante, de l'homme face à la mort. Robert Redeker nous invite à explorer le gouffre d'incompréhension qui sépare le soldat de la société civile actuelle à la lumière d'un brillant arrière-plan philosophique et historique s'attachant à cerner l'essence de la guerre. (shrink)

A uniquely playful and incisive illustrated collection of Zen teaching stories from one of America's best-known and most-respected Zen masters. A Modern Classic. In the tradition of the great koan collections and the extensive records of ancient masters, Robert Aitken--one of America's best-known and most-respected Zen masters--distills a lifetime of teaching down to its essence. Intriguing, playful, and deceptively easy to read, Zen Master Raven is a brilliant encapsulation of Zen in over a hundred koan-like encounters--featuring curious beginners like (...) Mallard and Mole, to teachers-in-training like Porcupine, to the profound wisdom of masters like Brown Bear, Moose Roshi, and Zen Master Raven himself. (shrink)

This book argues that the Russian-British philosopher Isaiah Berlin should primarily be understood through British idealism. Though he adopted Kantian methodology and a view of people as purposive beings, he rejected the Idealists' monism and theories of positive liberty. Robert A. Kocis demonstrates how, like Michael Oakeshott and R. G. Collingwood, Berlin can be seen as a 'post-Idealist' thinker, invested in the implications of that rich tradition.

In this final volume of Robert Denoon Cumming's four-volume history of the phenomenological movement, Cumming examines the bearing of Heidegger's philosophy on his original commitment to Nazism and on his later inability to face up to the implication of that allegiance. Cumming continues his focus, as in previous volumes, on Heidegger's connection with other philosophers. Here, Cumming looks first at Heidegger's relation to Karl Jaspers, an old friend on whom Heidegger turned his back when Hitler consolidated power, and who (...) discredited Heidegger in the denazification that followed World War II. The issues at stake are not merely personal, Cumming argues, but regard the philosophical relevance of the personal. After the war Heidegger disavowed Sartre, a move related to Heidegger's renunciation of his association with the phenomenological movement at large, and one that illustrates the dynamics of the history Cumming himself has completed. Serving as convincing punctuation for this remarkable series, this book demonstrates the importance of the history of philosophy in coming to grips with the proclaimed end of philosophy. (shrink)

In the third volume of his history of the phenomenological movement, Robert Denoon Cumming argues that their differences involve differences in method; whereas Husserl follows a "method of clarification," with which he eliminates ...

Gascoigne, Robert In October 1962, the world was at imminent risk of nuclear war. In response to the failed CIA backed 'Bay of Pigs' invasion, Soviet Premier Nikita Krushchev had authorized the stationing of nuclear missiles in Cuba, only ninety miles from the coast of Florida. In response, President John F. Kennedy had ordered a blockade of Cuba, which the Soviet Union regarded as an act of war. In fact, the world came much closer to a nuclear exchange than (...) has long been realized. On October 27th 1962 the Soviet submarine B59 was tracked by a group of United States warships, made up of eleven destroyers and an aircraft carrier, which were using non-lethal practice depth-charges in an attempt to bring the submarine to the surface. The submarine had lost radio contact with Moscow, which-as we will see-had very shortly beforehand ordered the freighters carrying nuclear missiles to return home. Under the intense pressure of the situation, the captain of the submarine-who thought that war may already have broken out-was determined not to allow Russia to be humiliated by the capture of his submarine, and was prepared to fire a nuclear torpedo at the surrounding American warships. Three officers had to give permission for a nuclear missile to be launched-the captain himself, the political officer, and Vasili Alexandrovich Arkhipov, who, although second-in-command of submarine B59, was commander of the flotilla of submarines to which it belonged. Arkhipov overruled his brother officers and refused to authorize the launch of the torpedo. The world owes a great debt of gratitude to this Soviet sailor who may have prevented a nuclear exchange between the Soviet Union and the United States. My father once told me how an American priest had recounted to him that, during the height of the Cuban missile crisis, the queues for confession at New York's St Patrick's cathedral stretched all the way down the nave and out onto Fifth Avenue. Given the penitential practices and beliefs of the time, and the actual state of events, there was indeed good reason for that! (shrink)

Robert Mayhew’s _Theophrastus of Eresus: On Winds_ includes an edition of the Greek text with an English translation and lengthy commentary on the sole Peripatetic treatise devoted to winds.

The rapid commercialization of applied genetics in the mtd-1970s, accompanied by a sudden rise in academic-corporate partnerships, raised questions about the impacts these linkages have had on the social and professional norms of scientists. The extent and pattern of faculty tnvolvement in commercialization of biological research is largely an unexplored area. This article provcdes a quantitative assessment of the linkages between biology faculty in American uncverscties and the newly formed biotechnology industry. The results of thes study, covering the period 1985-88, (...) show that academic scientists responded en masse to participating in the commercialization of genetecs research by estabhshmg formal associations with many of the new biotechnology compances. A data base consisting of 889 U.S. and Canadian biotechnology companies and 832 sccentcsts who had formal ties to them was developed over a four-year period. The patterns of academic-corporate Icnkages are revealed by institution. Three universities with the most commercially active faculty are Harvard, Stanford, and MIT. Of the 359 bcomedeca! scientists and geneteccsts who were members of the Nateonal Academy of Sceences, at minimum, 37% had formal ties with the biotechnology industry. (shrink)

I. the view that reasons cannot be causes. II. the view that the explanatory relevance of psychological states such as beliefs and intentions derives from their content, their explanatory role is not causal and we thus have no good reason to ascribe causal power to them. III. the idea that if the mental supervenes on the physical, then what really explains our actions is the physical properties determining our propositional attitudes, and not those attitudes themselves. IV. the thesis that since (...) there are no laws linking (intentional) mental states to actions, those states cannot be genuine causes of action. (shrink)

In this introductory paper, we assess the current status of blindsight -- the phenomenon in which patients with damage to their primary visual cortex retain the ability to detect, discriminate and localize visual stimuli presented in areas of their visual field in which they report that they are subjectively blind. Blindsight has garnered a great deal of interest and critical research, in part because of its important implications for the philosophy of mind. We briefly consider why this is so, and (...) then go on to examine three empirical questions which have fuelled challenges to the validity of blindsight as a distinct neuropsychological phenomenon. First, is blindsight simply degraded normal vision? Second, does blindsight depend on undamaged areas of primary visual cortex? Third, does evidence that blindsight patients are aware of moving stimuli undermine the apparent dissociation between access to visual information and visual experience in blindsight? In the course of the review we introduce the four other papers on blindsight in this issue. We conclude that, although patients with primary visual cortex damage may indeed perceive moving stimuli, there is still good evidence for a dissociation between access to information and phenomenal experience which cannot be accounted for in terms of degraded normal vision or undamaged primary visual cortex. (shrink)

What are the possibilities for religious experience in the twenty-first century? While aggressive atheists might respond “None,” in thunder, any good Peircean knows we should not foreclose inquiry. For those who retain a post-orthodox religious temperament in post-modernity, Robert S. Corrington’s evolving account of Ecstatic Naturalism might prove a challenging, engaging framework for a transcendental naturalism. If one can read Emerson and Thoreau and ignore their religious dimension, so be it—attunement is crucial for Corrington, cultivating the habits of thought, (...) the psychosemiosis that enables an engagement with Ecstatic Naturalism and a recovery of the sacred. Those inclined to an experiential, naturalistic... (shrink)