Interactive social cognition theory and approaches of developmental psychology widely agree that central aspects of emotional and social experience arise in the unfolding of processes of embodied social interaction. Bi-directional dynamical couplings of bodily displays such as facial expressions, gestures, and vocalizations have repeatedly been described in terms of coordination, synchrony, mimesis, or attunement. In this paper, I propose conceptualizing such dynamics rather as processes of affective resonance. Starting from the immediate phenomenal experience of being immersed in interaction, (...) I develop the philosophical notion of affective resonance to refer to a dynamic entanglement of moving and being-moved in relation. The concept of affective resonance makes visible that the interaction dynamic itself creates an affective experience rather than transmitting internal feeling states between pre-existent individuals. This leads to a philosophical framework in which relationality and ontogeny are primary over separate individuals, and in which the naturalistic distinction of a fundamental physical level versus an emerging level of social processes has to be given up. (shrink)

We propose a realistic device for detecting objects almost without transferring a single quantum of energy to them. The device can work with an efficiency close to 100% and relies on two detectors counting both presence and absence of the objects. Its possible usage in performing fundamental experiments as well as possible applications are discussed.

Transcranial magnetic stimulation, EEG, and behavioral studies by our group implicate spurious activation of speech perception neurocircuitry in the genesis of auditory hallucinations in schizophrenia. The neurobiological basis of these abnormalities remains uncertain, however. We review our ongoing studies, which suggest that altered cortical coupling underlies speech processing in schizophrenia and is expressed via disrupted gamma resonances and impaired corollary discharge function of self-generated verbal thought.

Storytelling pivots around stance seen as a window unto emotion: storytellers project a stance expressing their emotion toward the events and recipients preferably mirror that stance by affiliating with the storyteller’s stance. Whether the recipient’s affiliative stance is at the same time expressive of his/her emotional resonance with the storyteller and of emotional contagion is a question that has recently attracted intriguing research in Physiological Interaction Research. Connecting to this line of inquiry, this paper concerns itself with storytellings of (...) sadness/distress. Its aim is to identify factors that facilitate emotion contagion in storytellings of sadness/distress and factors that impede it. Given the complexity and novelty of this question, this study is designed as a pilot study to scour the terrain and sketch out an interim roadmap before a larger study is undertaken. The data base is small, comprising two storytellings of sadness/distress. The methodology used to address the above research question is expansive: it includes CA methods to transcribe and analyze interactionally relevant aspects of the storytelling interaction; it draws on psychophysiological measures to establish whether and to what degree emotional resonance between co-participants is achieved. In discussing possible reasons why resonance is (not or not fully) achieved, the paper embarks on an extended analysis of the storytellers’ multimodal storytelling performance (reenactments, prosody, gaze, gesture) and considers factors lying beyond the storyteller’s control, including relevance, participation framework, personality, and susceptibility to emotion contagion. (shrink)

Since most of the functions in cells are mediated by multimeric protein complexes, the determination of protein–protein interactions is an important step in the study of cellular mechanisms. Traditionally, after screening for possible target interactors by means of a yeast two‐hybrid screen, several methods are used to validate the initial result before carrying out functional experiments. Nowadays, non‐invasive fluorescence‐based methods like Bioluminescence Resonance Energy Transfer (BRET) and Fluorescence Resonance Energy Transfer (FRET) are widely used in the study of protein–protein interactions (...) in living cells. In the present review, we address the individual strengths and weaknesses of both RET approaches, providing information on their possible future use in the study of G protein‐coupled receptor oligomerization. BioEssays 30:82–89, 2008. © 2007 Wiley Periodicals, Inc. (shrink)

Embodied and phenomenological approaches to neuropsychiatry have proven to be promising for assessing social cognition and its impairments. Second-person neuroscience has demonstrated that the dynamics of social interaction make a difference when it comes to how people understand each other. This article presents the Perceptual Crossing Experiment (PCE) as a paradigm for studying real-time dyadic embodied interactions in the context of schizophrenia. We draw on the phenomenological concept of interbodily resonance (IR) and show how the PCE can be used (...) to accurately model and assess IR. We then turn to disembodied interaction in schizophrenia and finally propose the PCE as a translational tool for systematically assessing the hindered IR that individuals with schizophrenia suffer from. We offer an experimental approach to phenomenology which could be informative for the development of more embodied interventions aiming to remedy the profoundly disrupted social life that patients with schizophrenia live with. (shrink)

Asif A. Ghazanfar,1,3,* Hjalmar K. Turesson,1,3 statistical pattern recognition [16, 17] and psychophys- Joost X. Maier,1 Ralph van Dinther,2 ics [13, 18–23] have suggested that formants are signif- Roy D. Patterson,2 and Nikos K. Logothetis1 icant contributors to these indexical cues. It is likely, 1Max Planck Institute for Biological Cybernetics then, that detecting formants could have provided 72076 Tuebingen ancestral primates with indexical cues necessary for Germany navigating the complex social interactions that are the 2Centre for the Neural Basis of (...) Hearing essence of primate societies. One important indexical Department of Physiology cue is body size. Formant cues related to body size University of Cambridge could be used by monkeys to determine the sex (in sex- CB2 3EG Cambridge ually dimorphic species), degree of potential threat (e.g., United Kingdom whether a competitor is larger or smaller), and/or age of an individual, as such cues do for human listeners [13, 18, 20, 21]. Summary Formants are the result of acoustic filtering by the supralaryngeal vocal tract—the nasal and oral cavities Vocal-tract resonances (or formants) are acoustic sigabove the vocal folds. During vocal production, pulses natures in the voice and are related to the shape and of air generated by the rapid movement of the vocal length of the vocal tract. Formants play an important folds produce an acoustic signal. The frequency of these role in human communication, helping us not only to pulses—the glottal-pulse rate—determines the fundadistinguish several different speech sounds [1], but mental frequency of the signal, which in turn is perceived also to extract important information related to the as pitch. As the signal passes through the supralaryngphysical characteristics of the speaker, so-called ineal vocal tract, it excites resonances, resulting in the dexical cues. How did formants come to play such an enhancement of particular frequency bands; these are important role in human vocal communication? One the formants.. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Resonance and Response:Dewey, Merleau-Ponty, and Ecological EthicsMatthew Williams-WyantIntroductionThe contributions of Dewey and Merleau-Ponty exhibit a kinship rarely seen in philosophy. This uncanny similarity between two thinkers who shared no known direct contact and were separated by an ocean becomes less mysterious considering their shared situation and approach grounded in lived experience. For Dewey, the denotative-empirical method is a means to study things "on their own account" (Experience and Nature, (...) LW 1:14). Through selective emphasis, the inquirer is open within primary experience to the expressive movement of the object of inquiry. Merleau-Ponty's notion of interrogation seeks a similar aim in motivating Being to creatively express itself. In the act of expression, the reverberations of nature emerge, as Dewey notes, in "a perfect integration" of substance and form (Art as Experience, LW 10:114). The resonances of nature qua reverberations in turn resonate—evoke qualitative, non-cognitive meanings—between the inquirer and the selected object of inquiry establishing a resonance between our conceptions of the concrete world. The similarity between Dewey and Merleau-Ponty, then, is due to their attunement to this resonance.Perspective—the situated, lived context through which each person is attuned—prevents a one-for-one mapping of Dewey's thought onto Merleau-Ponty and vice versa.1 However, the resonance between these two thinkers establishes a complementary approach to ethics. In this paper, I argue that the philosophy of Merleau-Ponty and the philosophy of Dewey, when read together, provide a clear path from an aesthetic point of departure to a genuinely ecological ethics. The aesthetic foundation of Dewey's denotative-empirical method benefits from Merleau-Ponty's notion of interrogation grounded on his discussion of the body. In turn, Dewey's ethical contributions give voice [End Page 40] to the implicit ethics present but never explicitly formulated by Merleau-Ponty. The result is an ethical relation of responsiveness that accounts for the plurality of values and the porous, ever-changing boundaries between nature and human activity.1. The "Problem" of ExperienceA genuinely ecological ethics, one founded on the intertwined relation between human activity and nature, requires an approach that avoids the epistemological traps common to many philosophical positions. In framing interrogation as a necessary revision to traditional philosophical approaches, Merleau-Ponty indirectly addresses this concern.For Merleau-Ponty, interrogation is a response to a specific situation raised through the inadequacies of previous modes of philosophical inquiry; namely, reflection, dialectic, and intuition. Each of these perspectives employs a view from above—a "pensée de survol"—resulting in an insurmountable break between our knowledge of the world and the world itself. In attempting to overcome our everyday naïveté through philosophical understanding, the philosophies of reflection "replaces the 'world' with the 'Being-thought'" (Visible and the Invisible 43). In doing so, it remains naïve to the presuppositions that accompany any mode of philosophy that analyzes Being as if the observer were not already caught up in the movement of being. Dialectical philosophy has often been encumbered by formulations that mistake the fluidity of the dialectic itself for a rigid set of stages marked by complete and exhaustive concepts such as Fichte's thesis-antithesis-synthesis or Sartre's Being and Nothingness (Visible and the Invisible 94). According to Merleau-Ponty, it forgets, or ignores, the openness of meaning as it intertwines with others and transcends its previous moment. Finally, philosophical inquiries grounded in intuition run the risk of bifurcating, and ultimately reifying, fact and essence rather than seeing these two aspects as abstract moments, or dependent parts, of concrete existence (Visible and the Invisible 113).Dewey recognizes a similar problem when philosophers emphasize the need for a definition of experience. If our approach to philosophical inquiry was done correctly, we would not see experience as an epistemological stumbling block, but see it for what it is, our point of access to the world. This is what the denotative-empirical method attempted to show.2 For Dewey, traditional theories on the interaction between human activity and nature "are really elaborations of the same sort of assumptions … assumptions which first make a division where none exists, and... (shrink)

This paper investigates whether AI can possess wisdom, a complex and deeply human capacity. We adopt an interdisciplinary approach, drawing on philosophy, 4E cognition, Material Engagement Theory, and engaged epistemology, to argue that wisdom is a dynamic force unfolding through meaningful life experiences and resonant interactions with the world. Central to our discussion is Rosa's concept of resonance, essential for fostering personal growth, emotional empathy, as well as existential and bodily connectedness to the world and its unfolding into an (...) uncertain future. Despite the advanced capabilities of AI/Large Language Models (LLMs), we demonstrate their inability to embody wisdom due to their lack of deep sense-making, embodied interaction, and meaningful engagement with the world and future potentials. We emphasize the need for cultivating human wisdom to ensure technological advancements enrich rather than diminish the human experience, advocating for a balanced and reflective human-technology relationship. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Journal of Aesthetic Education 39.2 (2005) 36-57 [Access article in PDF] "Being With": The Resonant Legacy of Childhood's Creative Aesthetic Lori A. Custodero Teachers College, Columbia University Introduction...enrichment of the present for its own sake is the just heritage of childhood....1In this paper, the qualities of artistic pursuit exemplified in the musical play of children and the compositional processes of adults provide a context for exploring how (...) "being with" influences teaching and learning. Specifically I propose that "being with" music generates a sense of the aesthetic as we both transform musical materials — timbres, pitches, rhythms, phrases, harmonies — and are transformed by our experiences with them, and that "being with" others as we partake in musical activity often broadens and deepens that experience. In many ways, this is an exploration into why childhood matters, how it functions as a mirror for our adult lives as we experience and revel in the seemingly miraculous moments of aesthetic insight, where the familiar is welcomed with fresh perception and the addition of novelty is greeted as the solution to a previously unfathomable problem. It is also about why children matter, as our responses to their ways of being connect and transform us as adults. In this piece, recorded observations of children's musicality are juxtaposed with first-person accounts of adults' creative processes, revealing contributions to our understanding of artistry-in-action as it is manifested in both the musical and the pedagogical. The Aesthetic in Childhood and Adulthood To be "in the moment" is to encounter the aesthetic — fully engaged in an activity for which one's individual contributions are perceived as vital, aware of surprise relationships between seemingly disparate phenomena, and enveloped by sensory messages of color, sound, and movement meeting personal criteria for beauty. Such experiences exemplify features of artistry, an approach defined by openness to possibility and orientation toward discovery, where cues emanating from involvement in activity are clearly interpreted and utilized, and reflection is an ongoing process informing action. Characterized by a sense of wonder and ability to imagine and invent, the creative worlds of young children have provided a source of artistic genesis cited by composers, performers, psychologists, and educators.2Edith Cobb's thoughtful, groundbreaking account of the relationship between childhood and artistry, The Ecology of Imagination in Childhood, was introduced by Margaret Mead, who highlighted the work's thesis: "that in the imaginative experiences of childhood could be found the essential kernels of the highest forms of human thought."3 The legacy of childhood is universal to our existence; in acknowledging its contributions to ontological and cultural artistry, we can both connect personal histories across the [End Page 36] lifespan and identify characteristic trends across a spectrum of aesthetic rendering.4One trait common to both the child and the creative adult is a focused attentiveness to perceived affordances, that is, materials and human resources accessible in the environment. Acting upon and with these resources,children and artists become aesthetic agents as sensitivity to both experience and milieu combine to produce relevant and innovative outcomes.5 These two interactive dimensions have been described in interviews with composers I have interviewed as "being with the moment" and "being with yourself and at the same time with another" and are operating in the musical play of children, as noted in this description recorded by a mother/student: On Thanksgiving Day, we had a family gathering of sixteen people, five of whom are under the age of eight years. Three-year-old Louise is thrilled to be with her female cousins, who all dress up in ballet-type frilly costumes in order to put on a "show" for the family. Cousin Lily, now eight years old, assumes the role of pianist, while Louise, and five-year-old cousin Amy creatively dance to Lily's improvised accompaniment. Their movements are directly related to Lily's playing, in her fluidity and well as "jumps!" Here, family members serve as catalysts for creative activity — costumes and musical instruments in the environment... (shrink)

Pickering & Garrod deserve appreciation for their cogent argument that dialogue merits greater scientific consideration. Current models make little contact with behaviors of dialogue, motivating the interactive alignment theory. However, the theory is not truly “mechanistic.” A full account requires both representations and processes bringing those representations into harmony. We suggest that Grossberg 's adaptive resonance theory may naturally conform to the principles of dialogue.

Throughout its long history, national music has not only showcased its unique charm and artistic significance through cultural and economic evolution but has also acted as a medium for spiritual and communal expression. However, in the contemporary global landscape, the development of minority music theory, particularly within the Guangxi ethnic communities, faces significant challenges. These include environmental changes, loss of distinctive musical characteristics, and a dwindling number of tradition bearers. Minority music theory, a vital subset of Chinese national music theory, (...) reflects the rich traditional music heritage of China and holds substantial philosophical and religious value. From a multicultural perspective, the music of Guangxi's ethnic minorities demonstrates a dynamic evolution, influenced increasingly by interactions with diverse cultural and religious ideologies. Despite these positive trends, the theoretical underpinnings of Guangxi's minority music encounter profound challenges in today's global music culture environment, testing its resilience and capacity to adapt without losing its intrinsic value. To effectively foster the development and reform of Guangxi ethnic music, it is crucial to delve into the philosophical and spiritual dimensions that underlie its traditional practices. This exploration seeks not only to preserve but to rejuvenate Guangxi’s music theory, drawing on historical insights and contemporary multicultural dialogues. The goal is to ensure that the development of Guangxi’s ethnic music theory progresses in a manner that respects its heritage while embracing the opportunities presented by a multicultural world. (shrink)

Understanding biological systems in terms of scientific materialism has arguably reached a frontier, leaving fundamental questions about their complexity unanswered. In 1998, Friedrich Cramer proposed a general resonance theory as a way forward. His theory builds on the extension of the quantum physical duality of matter and wave to the macroscopic world. According to Cramer’ theory, agents constituting biological systems oscillate, akin to musical soundwaves, at specific eigenfrequencies. Biological system dynamics can be described as “Symphonies of Life” emerging from the (...) resonance (and dissonance) of eigenfrequencies within the interacting collective. His theory has potential for studying biological problems of increasing complexity in a fast‐changing Anthropocene from a new and transdisciplinary angle. Despite data becoming increasingly available for analyses, Cramer's theory remains ignored and therefore untested a quarter century after its publication. This paper discusses how the theory can move to quantitative assessments and application. Cramer's general resonance theory deserves revival. (shrink)

The human capacity for intersubjective engagement is present, even when one is limited in speaking, pointing, and coordinating gaze. This paper examines the everyday social interactions of two differently-disposed actors—a non-speaking autistic child and his speaking, neurotypical mother—who participate in shared attention through dialogic turn-taking. In the collaborative pursuit of activities, the participants coordinate across multiple turns, producing multi-turn constructions that accomplish specific goals. The paper asks two questions about these collaborative constructions: 1) What are their linguistic and discursive structures? (...) 2) How do embodied actions contribute to these constructions? Findings show that the parent and child repeatedly co-produced multi-turn constructions that had consistent structures, implying a sophisticated ability to anticipate the completion of action trajectories. Examining the embodied actions of interactants revealed that the child often accommodated to the parent’s demands for participation. Nonetheless, the child occasionally pursued his own goals by improvising with and within multi-turn constructions. He launched constructions to redirect parental attention, and otherwise produced surprising actions within the turn-taking structure of these constructions. The paper concludes that multi-turn constructions in the midst of activities are a primordial site in which to begin observing the competencies of non-speaking autistic children for intersubjective engagement. (shrink)

In this paper, we propose an examination of the shared connections between the French philosopher, Maurice Merleau-Ponty and the Austro-Hungarian movement theorist, Rudolf Laban.In many ways Merleau-Ponty''s philosophy demonstrates a synthesis of the best in existen-tialism and phenomenology. In like manner, Rudolf Laban was a synthesizer of experiences and theories of movement.

Magic angle spinning (MAS) NMR methods provide a means of obtaining high resolution structural data on rhodopsin and its photoin termediates. Current work has focused on the structure of the retinal chromophore and its interactions with surrounding protein charges. The recent development of MAS NMR methods for measuring internuclear distances with a resolution of ∼0.2 will complement diffraction methods for addressing key mechanistic questions.

Autism is a group of complex neurodevelopmental disorders characterized by impaired social interaction and restricted/repetitive behavior. We performed a large-scale retrospective analysis of 1,996 clinical neurological structural magnetic resonance imaging (MRI) examinations of 781 autistic and 988 control subjects (aged 0 to 32 years), and extracted regionally distributed cortical thickness measurements, including average measurements as well as standard deviations which supports the assessment of intra-regional cortical thickness variability. The youngest autistic participants (< 2.5 years) were diagnosed after imaging and (...) were identified retrospectively. The largest effect sizes and the most common findings not previously published in the scientific literature involve abnormal intra-regional variability in cortical thickness affecting many (but not all) regions of the autistic brain, suggesting irregular gray matter development in autism that can be detected with MRI. Atypical developmental patterns have been detected as early as 0 years old in individuals who would later be diagnosed with autism. (shrink)

We argue that theory-of-mind (ToM) approaches, such as “theory theory” and “simulation theory”, are both problematic and not needed. They account for neither our primary and pervasive way of engaging with others nor the true basis of our folk psychological understanding, even when narrowly construed. Developmental evidence shows that young infants are capable of grasping the purposeful intentions of others through the perception of bodily movements, gestures, facial expressions etc. Trevarthen’s notion of primary intersubjectivity can provide a theoretical framework for (...) understanding these capabilities and his notion of secondary intersubjectivity shows the importance of pragmatic contexts for infants starting around one year of age. The recent neuroscience of resonance systems (i.e., mirror neurons, shared representations) also supports this view. These ideas are worked out in the context of an embodied “Interaction Theory” of social cognition. Still, for more sophisticated intersubjective interactions in older children and adults, one might argue that some form of ToM is required. This thought is defused by appeal to narrative competency and the Narrative Practice Hypothesis (or NPH). We propose that repeated encounters with narratives of a distinctive kind is the normal route through which children acquire an understanding of the forms and norms that enable them to make sense of actions in terms of reasons. A potential objection to this hypothesis is that it presupposes ToM abilities. Interaction Theory is deployed once again to answer this by providing an alternative approach to understanding basic narrative competency and its development. (shrink)

Pessoa et al. (1998a) summarize a wide body of data suggesting that perceptual filling-in phenomena can be attributed to neural filling-in processes. However, they reject, on philosophical grounds, the hypothesis that filled-in representations in the brain are the immediate substrate of visual percepts. It is proposed in this commentary that resonant binding between distributed cortical areas may instead be the crucial ingredient for conscious visual percepts, and that filling-in processes may facilitate the interactions between behaving organisms and object surfaces. (...) These suggestions circumvent some of the philosophical problems associated with the idea of localized visual representations. (shrink)

How does your mind work? How does your brain give rise to your mind? These are questions that all of us have wondered about at some point in our lives, if only because everything that we know is experienced in our minds. They are also very hard questions to answer. After all, how can a mind understand itself? How can you understand something as complex as the tool that is being used to understand it? This book provides an introductory and (...) self-contained description of some of the exciting answers to these questions that modern theories of mind and brain have recently proposed. Stephen Grossberg is broadly acknowledged to be the most important pioneer and current research leader who has, for the past 50 years, modelled how brains give rise to minds, notably how neural circuits in multiple brain regions interact together to generate psychological functions. This research has led to a unified understanding of how, where, and why our brains can consciously see, hear, feel, and know about the world, and effectively plan and act within it. The work embodies revolutionary Principia of Mind that clarify how autonomous adaptive intelligence is achieved. It provides mechanistic explanations of multiple mental disorders, including symptoms of Alzheimer's disease, autism, amnesia, and sleep disorders; biological bases of morality and religion, including why our brains are biased towards the good so that values are not purely relative; perplexing aspects of the human condition, including why many decisions are irrational and self-defeating despite evolution's selection of adaptive behaviors; and solutions to large-scale problems in machine learning, technology, and Artificial Intelligence that provide a blueprint for autonomously intelligent algorithms and robots. Because brains embody a universal developmental code, unifying insights also emerge about shared laws that are found in all living cellular tissues, from the most primitive to the most advanced, notably how the laws governing networks of interacting cells support developmental and learning processes in all species. The fundamental brain design principles of complementarity, uncertainty, and resonance that Grossberg has discovered also reflect laws of the physical world with which our brains ceaselessly interact, and which enable our brains to incrementally learn to understand those laws, thereby enabling humans to understand the world scientifically. Accessibly written, and lavishly illustrated, Conscious Mind/Resonant Brain is the magnum opus of one of the most influential scientists of the past 50 years, and will appeal to a broad readership across the sciences and humanities. (shrink)

Norbert Wiener and J.B.S. Haldane suggested during the early thirties that the profound changes in our conception of matter entailed by quantum theory opens the way for our thoughts, and other experiential or mind-like qualities, to play a role in nature that is causally interactive and effective, rather than purely epiphenomenal, as required by classical mechanics. The mathematical basis of this suggestion is described here, and it is then shown how, by giving mind this efficacious role in natural process, the (...) classical character of our perceptions of the quantum universe can be seen to be a consequence of evolutionary pressures for the survival of the species. (shrink)

BackgroundFear of abandonment and aloneness play a key role in the clinical understanding interpersonal and attachment-specific problems in patients with borderline personality disorder and has been investigated in previous functional Magnet Resonance Imaging studies. The aim of the present study was to examine how different aspects of attachment representations are processed in BPD, by using for the first time an fMRI attachment paradigm including personalized core sentences from the participants’ own attachment stories. We hypothesized that BPD patients would show increased (...) functional involvement of limbic brain regions associated with fear and pain when presented personalized attachment relevant stimuli representing loneliness compared to healthy controls.MethodsWe examined the attachment classifications of 26 female BPD patients and 26 female HC using the Adult Attachment Projective Picture System. We used an fMRI-adapted attachment paradigm to investigate the neural correlates of attachment. All participants were presented three personalized sentences extracted from their AAP attachment narrative, combined with standardized AAP pictures representing being alone or in interactive attachment situations.ResultsAs expected, the classification of unresolved attachment was significantly greater in BPD compared to HC. BPD patients showed increased fMRI-activation in brain areas associated with fear, pain, and hyperarousal than HC when presented with personalized attachment-relevant alone stimuli. In particular, pictures with monadic attachment situations induced greater anterior medial cingulate cortex, anterior insula, amygdala, thalamus and superior temporal gyrus activation in the patient group.ConclusionThe results point to increased fMRI-activation in areas processing emotional distress and painful experiences in BPD patients. In particular, the emotional cascade reflecting attachment distress was evoked by combining monadic pictures, representing abandonment and aloneness, with the patients’ personalized narrative material. Our results confirmed and replicated previous results that illustrate once again the high relevance of aloneness and feelings of abandonment for BPD in the context of attachment trauma. Moreover, our results support the hypothesis of hypermentalization in response to attachment distress as a core feature of social-cognitive impairment in BPD associated with common treatment implications across different therapeutic orientations. (shrink)

Previous research has demonstrated the influence of emotions during linguistic processing, indicating the interactivity of both processes in the brain. However, little is known regarding such interplay in a second language (L2). This study addressed this question by examining the reading effects of syntactic violations while processing L2 emotional and neutral statements. Forty-six Spanish-English bilinguals with various levels of L2 proficiency and emotional resonance (i.e. capability for emotional experience in L2) were presented with a self-paced sentence reading task. Sentences contained (...) positive (16), neutral (16) and negative (16) verbs, half of them presented in agreement and half in disagreement with the preceding pronoun. Analysis of verb reading times using linear mixed effects modelling revealed a significant interaction between syntactic violation, verb valence and emotional resonance, suggesting that stronger emotional L2 experience results in a higher saliency of negative verbs, reducing the impact of syntactic violations. (shrink)

Spoken language is an innate ability of the human being and represents the most widespread mode of social communication. The ability to share concepts, intentions and feelings, and also to respond to what others are feeling/saying is crucial during social interactions. A growing body of evidence suggests that language evolved from manual gestures, gradually incorporating motor acts with vocal elements. In this evolutionary context, the human mirror mechanism (MM) would permit the passage from “doing something” to “communicating it to someone (...) else.” In this perspective, the MM would mediate semantic processes being involved in both the execution and in the understanding of messages expressed by words or gestures. Thus, the recognition of action related words would activate somatosensory regions, reflecting the semantic grounding of these symbols in action information. Here, the role of the sensorimotor cortex and in general of the human MM on both language perception and understanding is addressed, focusing on recent studies on the integration between symbolic gestures and speech. We conclude documenting some evidence about MM in coding also the emotional aspects conveyed by manual, facial and body signals during communication, and how they act in concert with language to modulate other’s message comprehension and behavior, in line with an “embodied” and integrated view of social interaction. (shrink)

How does understanding occur in encounters of living beings? What is experienced by the interaction partners and what happens in the ‘In-Between’? And how can this be captured? In this paper an enactive approach to interaction is proposed with the focus on reciprocal inter-corporeal attunement and co-creation of meaning in a specific environment. As alternative framework this approach is applied to the interaction of d/Deaf persons and animals. In the interaction with an animal, verbal communication – (...) which is challenging for d/Deaf persons – is of secondary importance, so this frame is well suited to focus on intercorporeal attunement. In the interaction discourse regarding d/Deaf persons as well as Human-Animal-Interaction the assessment of the interaction process as such and embodied research methodologies are scarcely to be found. With the enactive approach new perspectives on the mechanisms of interaction and the influencing conditions can be opened as well as new approaches to respective research options. (shrink)

The elastic and radiative π + p scattering are studied in the framework of an effective Lagrangian model for the Δ ++ resonance and its interactions. The finite width effects of this spin-3/2 resonance are introduced in the scattering amplitudes through a complex mass scheme to respect electromagnetic gauge invariance. The resonant pole (Δ ++) and background contributions (ρ 0, σ, Δ, and neutron states) are separated according to the principles of the analytic S-matrix theory. The mass and width (...) parameters of the Δ ++ obtained from a fit to experimental data on the total cross section are in agreement with the results of a model-independent analysis based on the analytic S-matrix approach. The magnetic dipole moment determined from the radiative π + p scattering is $\mu _{\Delta ^{ + + } } = (6.14 \pm 0.51)$ nuclear magnetons. (shrink)

The automatic tendency to anthropomorphize our interaction partners and make use of experience acquired in earlier interaction scenarios leads to the suggestion that social interaction with humanoid robots is more pleasant and intuitive than that with industrial robots. An objective method applied to evaluate the quality of human–robot interaction is based on the phenomenon of motor interference (MI). It claims that a face-to-face observation of a different (incongruent) movement of another individual leads to a higher variance (...) in one’s own movement trajectory. In social interaction, MI is a consequence of the tendency to imitate the movement of other individuals and goes along with mutual rapport, sense of togetherness, and sympathy. Although MI occurs while observing a human agent, it disappears in case of an industrial robot moving with piecewise constant velocity. Using a robot with human-like appearance, a recent study revealed that its movements led to MI, only if they were based on human prerecording (biological velocity), but not on constant (artificial) velocity profile. However, it remained unclear, which aspects of the human prerecorded movement triggered MI: biological velocity profile or variability in movement trajectory. To investigate this issue, we applied a quasi-biological minimum-jerk velocity profile (excluding variability in the movement trajectory as an influencing factor of MI) to motion of a humanoid robot, which was observed by subjects performing congruent or incongruent arm movements. The increase in variability in subjects’ movements occurred both for the observation of a human agent and for the robot performing incongruent movements, suggesting that an artificial human-like movement velocity profile is sufficient to facilitate the perception of humanoid robots as interaction partners. (shrink)

This paper critiques the concept of resonant leadership which focuses on utilising emotional intelligence in managing an organisation. It is argued that the prevailing understandings of resonant leadership over-emphasise individual attributes and neglect the social processes of communication. This article proposes a re-conceptualisation of resonant leadership by drawing on pertinent principles from the Chinese classic Huainanzi (The Master of Huainan). Instead of linking resonance to emotional intelligence, ancient Chinese thinkers interpret the former as pre-existing mutual responsiveness (xiangying) (...) that contributes to synchrony, cooperation and harmony. A resonant leader promotes mutual responsiveness by modelling it and sustaining the conditions for people to (re)act and flourish according to the Way (dao). This study provides an original formulation of resonant leadership that shifts the attention from the creation and development of resonance by an emotionally attuned leader or manager, to the recognition and preservation of resonance by leaders, managers and other employees through interactive processes in an organisation. The proposed conception also illustrates a hybrid orientation of relationship-focused leadership styles that integrate key elements from the entity and relational perspectives at the workplace. (shrink)

The discovery and engineering of novel fluorescent proteins (FPs) from diverse organisms is yielding fluorophores with exceptional characteristics for live‐cell imaging. In particular, the development of FPs for fluorescence (or Förster) resonance energy transfer (FRET) microscopy is providing important tools for monitoring dynamic protein interactions inside living cells. The increased interest in FRET microscopy has driven the development of many different methods to measure FRET. However, the interpretation of FRET measurements is complicated by several factors including the high fluorescence background, (...) the potential for photoconversion artifacts and the relatively low dynamic range afforded by this technique. Here, we describe the advantages and disadvantages of four methods commonly used in FRET microscopy. We then discuss the selection of FPs for the different FRET methods, identifying the most useful FP candidates for FRET microscopy. The recent success in expanding the FP color palette offers the opportunity to explore new FRET pairs. (shrink)

BackgroundMild cognitive impairment is a common neurological disorder. Moxibustion has been shown to be effective in treating MCI, but its therapeutic mechanisms still remain unclear. This study mainly aimed to investigate the modulation effect of moxibustion treatment for patients with MCI by functional magnetic resonance imaging.MethodsA total of 47 patients with MCI and 30 healthy controls participated in resting-state fMRI imaging scans. Patients with MCI were randomly divided into true moxibustion group and sham moxibustion group. The degree centrality approach was (...) applied to distinguish altered brain functions. Correlation analysis was then performed to examine the relationships between the neuroimaging findings and clinical symptoms.ResultsCompared with HCs, patients with MCI mainly showed decreased DC in the left middle frontal cortex and bilateral middle cingulate cortex. After moxibustion treatment, the SHAM group had no significant DC findings, while TRUE group mainly showed significant increased DC in the bilateral MFC and MCC, as well as decreased DC in the left middle occipital cortex. Repeated measures analysis of variance showed significant interactions between the two groups of patients with MCI. In addition, the higher Mini-Mental State Examination score was significantly positively correlated with increased DC in the right MFC and left MCC after moxibustion treatment.ConclusionOur findings demonstrate that the potential value of moxibustion treatment on MCI, which adds new insights into the popular view that moxibustion treatment may slow cognitive decline in patients with MCI. (shrink)

There is a growing realization in cognitive science that a theory of embodied intersubjectivity is needed to better account for social cognition. We highlight some challenges that must be addressed by attempts to interpret ‘simulation theory’ in terms of embodiment, and argue for an alternative approach that integrates phenomenology and dynamical systems theory in a mutually informing manner. Instead of ‘simulation’ we put forward the concept of the ‘extended body’, an enactive and phenomenological notion that emphasizes the socially mediated nature (...) of embodiment. To illustrate the explanatory potential of this approach, we replicate an agent-based model of embodied social interaction. An analysis of the model demonstrates that the extended body can be explained in terms of mutual dynamical entanglement: inter-bodily resonance between individuals can give rise to self-sustaining interaction patterns that go beyond the behavioral capacities of isolated individuals by modulating their intra-bodily conditions of behavior generation. (shrink)

Emotional design is an important development trend of interaction design. Emotional design in products plays a key role in enhancing user experience and inducing user emotional resonance. In recent years, based on the user's emotional experience, the design concept of strengthening product emotional design has become a new direction for most designers to improve their design thinking. In the emotional interaction design, the machine needs to capture the user's key information in real time, recognize the user's emotional state, (...) and use a variety of clues to finally determine the appropriate user model. Based on this background, this research uses a deep learning mechanism for more accurate and effective emotion recognition, thereby optimizing the design of the interactive system and improving the user experience. First of all, this research discusses how to use user characteristics such as speech, facial expression, video, heartbeat, etc., to make machines more accurately recognize human emotions. Through the analysis of various characteristics, the speech is selected as the experimental material. Second, a speech-based emotion recognition method is proposed. The mel-Frequency cepstral coefficient of the speech signal is used as the input of the improved long and short-term memory network. To ensure the integrity of the information and the accuracy of the output at the next moment, ILSTM makes peephole connections in the forget gate and input gate of LSTM, and adds the unit state as input data to the threshold layer. The emotional features obtained by ILSTM are input into the attention layer, and the self-attention mechanism is used to calculate the weight of each frame of speech signal. The speech features with higher weights are used to distinguish different emotions and complete the emotion recognition of the speech signal. Experiments on the EMO-DB and CASIA datasets verify the effectiveness of the model for emotion recognition. Finally, the feasibility of emotional interaction system design is discussed. (shrink)

Crucial to the establishment of a scientific discipline is a body of knowledge organized around a set of instruments, interpretive techniques, and regimes of training in their application. In this paper, we trace the involvement of scientists and engineers at Varian Associates in the development of nuclear magnetic resonance spectrometers from the first demonstrations of the NMR phenomenon in 1946 to the definitive takeoff of NMR as a chemical discipline by the mid-1960s. We examine the role of Varian scientists in (...) constructing several models of NMR instruments for research scientists in the 1950s and the Varian efforts to influence the adoption of NMR as a standard tool for chemical analysis through Varian-supported publications, participation in scientific meetings, collaborations with academic chemists, workshops, and postdoctoral fellowships. Special attention is devoted to the development of the Varian A-60, the first commercial NMR instrument intended for the broadly trained chemist rather than a custom-built tool for the research specialist. Drawing on an examination of the use-rate of NMR instruments in chemical literature, the assessment of NMR in the chemical review literature by practitioners, and indicators of the establishment of a suitable funding environment for the growth of physics-based scientific instrumentation in the post-Sputnik era, we argue that the establishment of NMR as a discipline coincided with the adoption of the A-60 in the mid-1960s. During the period of our study, Varian Associates was a primary military contractor. This paper is intended to contribute to recent interest in the relation of military fundingto scientific enterprise during the Cold War and to the larger question of university-industry interactions in the growth of knowledge. (shrink)

With the ternary relationship of influence and cooperation between sign, object, and its interpreter in the semiotic rapport as a starting point, the present study aims to capture the “productive tension” of semiotics and communication in the Japanese advertising discourse. The advertisement, considered a semiotic system which ranks the fundamental functions of language in a particular manner, searches for new methods of communication, of message production, directing the sign towards the symbolic space of communication. In trying to measure this symbolic (...) fund of mass communication, the following text wishes to argue, from the perspective of rhetoric and cultural semiotics, that in the Japanese advertising message which is not transmitted mechanically between speaker and listener, one may recognise a model of impressiveness alongside a model of stimulation or of insertion . Also, calling on “syncretic” semiotics, this research devoted to the Japanese advertising discourse wishes to probe the way in which meaning is constructed through the act of signification resulted from the interaction of the verbal sentence with procedures and strategies that manifest themselves in several types of language, such as the visual, auditory, gestural, etc. (shrink)

The consistent tanh expansion method is successfully applied to the coupled integrable dispersionless system. A nonauto-Bäcklund transformation theorem includes two fields f and v 1 is obtained by using the CTE method. One obtains the consistent condition in the nonauto-BT theorem by means of the relation between the fields f and v 1. The CID system possesses the CTE solvability property by some detailed analysis. Many interactions between one soliton and multiple resonant solitons, and between one soliton and cnoidal (...) waves are generated by using the nonauto-BT theorem. The types of bright and gray two front waves are shown by some figures. In the meanwhile, the nonlocal symmetry is obtained by the truncated Painlevé method and the Möbious invariant form. The initial value problem and an auto-BT are constructed by the localization procedure. (shrink)

This article explores the use of interactive and kinetic technologies in contemporary art practice as a means by which artists engage with conditions of social and ecological crisis. In a context in which the perpetual exploitation of human and natural resources threatens the sustainability of the planet and all earthy life, the language of interactivity provides perspective into the interconnectivity of organisms and the interdependence of biological, social, economic and political systems. The interactive, kinetic work affords a distilled set of (...) relationships and movements that rely on connection and participation and, as such, serve as simple and relatable models of complex and interrelated systems. By engendering a sense of fragile suspension between sustainability and collapse – a felt experience of the present ecological crisis – the artists discussed incite affective responses through their works that are argued to be distinctly empathic in nature. Contemporary environmental theory provides insight into a shifting relationship between human and ‘nature’ that dissolves the previously instated binary in favour of an empathic consciousness, at the core of which is a recognition of the interdependence of living organisms. Art historical insight of interactivity as a means of production reveals a notable link between interactive art, destruction and trauma. The affective response engendered in contemporary works that grapple with concepts of transience and mortality relies on the very human knowledge of the body as a relatable site of experience, particularly pain and trauma. The idea of empathy as prefigured by violence and loss is particularly resonant in relation to contemporary ecological trauma. Works by artists including Rebecca Horn, Theo Jansen, Natalie Jeremijenko, Alan Rath, Lygia Clark, Alexandra Karakashian and Robert Krishner are discussed in terms of interactivity and kineticism as prompting empathic engagement in the context of environmental entropy. (shrink)

The mass media is a major source of health information for the public, and as such the quality and independence of health news reporting is an important concern. Concerns have been expressed that journalists reporting on health are increasingly dependent on their sources—including representatives of industries responsible for manufacturing health-related products—for story ideas and content. Many critics perceive an imbalance of power between journalists and industry sources, with industry being in a position of relative power, however the empirical evidence to (...) support this view is limited. The analysis presented here—which is part of a larger study of industry-journalist relationships—draws on in-depth, semi-structured interviews with representatives of health-related industries in Australia to inductively examine their perceptions of power relations between industry and journalists. Participants painted a picture in which journalists, rather than themselves, were in a position to control the nature, extent, and outcome of their interactions with industry sources. Our results resonate with the concept of “mediatisation” as it has been applied in the domain of political reporting. It appears that, from the perspective of industry representatives, the imposition of media logic on health-related industries may inappropriately influence the information that the public receives about health-related products. (shrink)

The theory of embodied cognition can provide HCI practitioners and theorists with new ideas about interac-tion and new principles for better designs. I support this claim with four ideas about cognition: (1) interacting with tools changes the way we think and perceive – tools, when manipulated, are soon absorbed into the body schema, and this absorption leads to fundamental changes in the way we perceive and conceive of our environments; (2) we think with our bodies not just with our brains; (...) (3) we know more by doing than by seeing – there are times when physically performing an activity is better than watching someone else perform the activity, even though our motor resonance system fires strongly during other person observa-tion; (4) there are times when we literally think with things. These four ideas have major implications for interaction design, especially the design of tangible, physical, context aware, and telepresence systems. (shrink)

A general framework by which dynamic interactions within a protein will promote the necessary series of structural changes, or “conformational cycle,” required for function is proposed. It is suggested that the free‐energy landscape of a protein is biased toward this conformational cycle. Fluctuations into higher energy, although thermally accessible, conformations drive the conformational cycle forward. The amino acid interaction network is defined as those intraprotein interactions that contribute most to the free‐energy landscape. Some network connections are consistent in every (...) structural state, while others periodically change their interaction strength according to the conformational cycle. It is reviewed here that structural transitions change these periodic network connections, which then predisposes the protein toward the next set of network changes, and hence the next structural change. These concepts are illustrated by recent work on tryptophan synthase. Disruption of these dynamic connections may lead to aberrant protein function and disease states. (shrink)

Designing and developing a digital musical instrument (DMI) to a level of refinement that provides musically rich applications and nuanced interaction capabilities requires a long-term commitment to both technical and creative aspects. This process often leads to the acquisition of sensory, communicative, and intuitive knowledge—dimensions of instrument design that are typically overlooked in mainstream discussions. This paper explores this development journey through the lens of three instruments: the Resonant Object Interface (ROI), the Floors, and the Table Floor. These (...) instruments have undergone extensive development, with the latest instrument building upon the lessons learned from the previous two. We discuss the challenges encountered during the ongoing refinement of these devices and our evolving interaction with their physical complexities. A key focus is the tacit knowledge gained through hands-on engagement, which, though often taken for granted once established, requires significant time and effort to develop. Further, we reflect on our experiences sharing these instruments with other musicians, highlighting how tacit engagement plays a critical role in the creation of new processes, materials, sensing technologies, and sensory experiences in the realm of digital musical instrument design. (shrink)

Deficits in social cognition and more specifically in communication have an important impact on the real-life functioning of people with schizophrenia. In particular, patients have severe problems in communicative-pragmatics, for example, in correctly inferring the speaker’s communicative intention in everyday conversational interactions. This limit is associated with morphological and functional alteration of the left middle temporal gyrus, a cerebral area involved in various communicative processes, in particular in the distinction of ironic communicative intention from sincere and deceitful ones. We performed (...) an fMRI study on 20 patients with SZ and 20 matched healthy controls while performing a pragmatic task testing the comprehension of sincere, deceitful, and ironic communicative intentions. We considered the L-MTG as the region of interest. SZ patients showed difficulties in the correct comprehension of all types of communicative intentions and, when correctly answering to the task, they exhibited a higher activation of the L-MTG, as compared to HC, under all experimental conditions. This greater involvement of the L-MTG in the group of patients could depend on different factors, such as the increasing inferential effort required in correctly understanding the speaker’s communicative intentions, and the higher integrative semantic processes involved in sentence processing. Future studies with a larger sample size and functional connectivity analysis are needed to study deeper the specific role of the L-MTG in pragmatic processes in SZ, also in relation to other brain areas. (shrink)

The article re-examines the relationship between the works of Alfred Schütz and Harold Garfinkel, focusing on their respective approaches to temporality in interaction. Although there are good reasons to emphasize the differences between Schütz’s notion of individual projects of action and Garfinkel’s interest in communicative sequencing, there is also an interesting historical connection. In order to elucidate this connection, the article provides a close reading of the steps that lead Schütz from his premise of ‘egological’ time consciousness to his (...) understanding of the reflexive and interactive process of meaning establishment and interpretation developed in his first book, _The Phenomenology of the Social World_ (1967 [1932]). The article reflects further upon which aspects of Schütz’s considerations resonated with Garfinkel in his formative years and how Garfinkel related to them variously in his later development of ethnomethodology. Hence, it appears that Garfinkel’s ethnomethodology successively departs from many of Schütz’s premises while simultaneously incorporating and further developing some of his notions on the sequential organization and temporal flux of interactive processes. (shrink)

Producing and interpreting functional brain data is part of the negotiation we imagine our brain. To take a closer look at the idea of brain imaging as a form of visual knowledge, it is necessary to put the research of today into a historical context. In my article I will point to a specific approach of functional imaging which depends on historical shifts entangled with the visual aspect of producing pictures of the brain. I will bring out the interaction (...) of issues like techniques, models and historical assumptions of the brain and link them with the way the brain images are presented. The aesthetic dimensions (Rancière) in the pictures are also questions of ethics and normativity. (shrink)

Insulin is stored within the pancreas in an inactive Zn2+‐bound hexameric form prior to release. Similarly, clinical insulins contain Zn2+ and form multimeric complexes. Upon release from the pancreas or upon injection, insulin only becomes active once Zn2+ disengages from the complex. In plasma and other extracellular fluids, the majority of Zn2+ is bound to human serum albumin (HSA), which plays a vital role in controlling insulin pharmacodynamics by enabling removal of Zn2+. The Zn2+‐binding properties of HSA are attenuated by (...) non‐esterified fatty acids (NEFAs) also transported by HSA. Elevated NEFA concentrations are associated with obesity and type 2 diabetes. Here we present the hypothesis that higher NEFA levels in obese and/or diabetic individuals may contribute to insulin resistance and affect therapeutic insulin dose‐response profiles, through modulation of HSA/Zn2+ dynamics. We envisage this novel concept to have important implications for personalized treatments and management of diabetes‐related conditions in the future. (shrink)

Mammalian brains contain a variety of self-centered socio-emotional systems. An understanding of how they interact with more recent cognitive structures may be essential for understanding empathy. Preston & de Waal have neglected this vast territory of proximal brain issues in their analysis.