UK general practitioners (GPs) are self-employed entrepreneurs running small businesses with commercial considerations. In this situation there is no clear distinction between information, self-promotion and advertising. In response to the growing public demand for more information about medical services, the medical profession should voluntarily accept the notion of soft self-promotion in the form of 'notices' or 'announcements' placed in newspapers. Newspapers are the most effective way of giving easy access to information. The resistance to newspapers may be more concerned with (...) preserving certain medical traditions than consideration of the public interest. The General Medical Council's (GMC's) arguments against soft self-promotion are seen as misguided paternalism, inconsistent and irrational. (shrink)

The myelin basic proteins are a set of peripheral membrane polypeptides which play an essential role in myelination. Their most well‐documented property is the unique ability to ‘seal’ the cytoplasmic aspects of the myelin membrane, but this is probably not the only function for these highly charged molecules. Despite extensive homology, the individual myelin basic proteins (MBPs) exhibit different expression patterns and biochemical properties, and so it is now believed that the various isoforms are not functionally equivalent in myelinating cells. (...) We now think that while the major MBPs are intracellular adhesion molecules, some of the quantitatively less abundant isoforms that are expressed very early in development may have regulatory effects on the myelination program. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:RESPONSE TO BRUCE MARSHALL GEORGE LINDBECK There is an abundance of il'iches in Bruce Marshalrs essay. He makes me understand hoth myse1f and Aquinas hetter than I biaid done hefore; and, interestingly, it is chiefly hy his exegesis of St. Thomas that he does :bhis. If I had referred more to the Thomistic ideas he elucidates when I wirus writing Natrure of Dootrine1 it would have!been a better hook. (...) What he calls the " somewhat notorious " example of the crusadeT"s Christus est Dominus is a good oase in point. It would ihave helped if I had made dear that I was thinking in medieval [ashion of a an individual rutterance, the product of a pa•riticular :second 1aJct of the intellect, the ·acl of composing and dividing, of judging ·such and such rto ibe rthe ca,se. In Aquinas' intellectual setting, judgments, not sentences in ·abstraiction from 1 acls of affirmation, were propositions capruble of being true or f.a1se. Many of my ·reruders had a more modern or "Platonic " understanding of rpropositions, and therefore missed the force of the e:xJam:ple ·as Marshall so carefully and rightly explains it. Among his contributions, the major one, however, is system- •a1tically to introduce into the disCUJssion the distinction between the " truth " and " justification " of beliefs or pI'oposi- "'" tionS.- Once the point is made, it is evident that " alethiology" and " epistemology " (to mention a cognate, though not ~den­ tical distinction) ·are, 1 at least in some contexts, partially independent variables. There is no one-to-one relation between different meanings or theories of truth and the v:arious views as to how we know such ·and such is true. It was my failure to make this point explicit which confosed Fr. Colman O'Neill, of blessed memory, ias well as a good many other readers (1as Bruce Marshall quite rightly notes, though, with excessive 408 404 GEORGEl LINDBECK kindness to me, he!blames the,readers rather than the 'author for the misunderstanding). Once iclarfiied, as it has lbeen done hy Mr. Marshall, the issue turns on ·whether,a classical " correspondence " theory of truth can be ioombined,with, to empfoy O'Neill's terminology, the use of "coherentist" and " pragmatist " epistemological criteria in justifying rbelieis. I ·am not sure ·that this is possible for those who e:xdude any reference to an idea.I observer or knower (whether real or hypothetical) when defining truth, hut for any theist r.for whom God is prima veritas, as he was for Aquinas, the answer is dearly in the affirmative. In God, and only in God, are knowledge and reality, not only in correspondence, hut directly known to correspond. Only in him do truth·and knowledge of truth, 1 aleth:iofogy and epistemology, ooindde. In 1human knowledge in via, in contrast, there is always a gap. Our ibe1ieTs may correspond to reality, hut we are justified in holding that they do so, not by directly seeing the correspondence, 1but by some other means. That those other means might in part or w:hole be coherentist or pragmatist cannot :be e:xduded a priori. It is true that in the caise of an Aristotelian 1such 1as Aquinas, coherence •and rpmctise 1are not explicitly accorded major roles in the epistemological justification of natural kno·wledge or scientia, yet even here they are not e:xduded. Nothing can quali[y ais 1an item of knowledge unless it coheres with all other scientia, and right pra.ctice (i.e., training in virtue) is indispensible :llor ethical kno,wledge. Nor need one cease fo be an Aris,totelian, 1as far ·as I can see, if one accepts the contempOO 'ary oommonpJaice that sense experience itself is heavily dependent on linguistic and non-linguistic pmctices which are in part ·acquired rthrough variaible forim:s of aicculturation and not simply through the actualization of 1genetically encoded propensities. One could still, despite this increased emphasis on prwctiice.and on coherence 1 with webs of 1belief, ibe 'able to affum in good Aristotelian,fashion tha;t the knowledge naturally accessible to ra:t]onal animals such,as we a.re is primarily justified RESPONCE TO BRUCE MARSHALL 405 iby reference to... (shrink)

A Leibniz class is a class of logics closed under the formation of term-equivalent logics, compatible expansions, and non-indexed products of sets of logics. We study the complete lattice of all Leibniz classes, called the Leibniz hierarchy. In particular, it is proved that the classes of truth-equational and assertional logics are meet-prime in the Leibniz hierarchy, while the classes of protoalgebraic and equivalential logics are meet-reducible. However, the last two classes are shown to be determined by Leibniz conditions consisting of (...) meet-prime logics only. (shrink)

SummaryThis article argues that Archibald Campbell's Necessity of Revelation can be viewed as the first application of the ‘science of human nature’, a characteristic branch of the Scottish Enlightenment, to the study of religious belief. Adopting Baconian and Newtonian methodological principles, Campbell set hypotheses, collected historical data, and inferred conclusions about the capabilities of human nature to come to fundamental religious ideas without the aid of revelation. He did so not only to reject the ‘deist’ position on the powers of (...) unassisted human reason, associated with Matthew Tindal's Christianity as Old as the Creation, but also to refute Campbell's conservative critics within the Church of Scotland who had earlier tried him for heresy. Campbell's example is that of a university professor using the experimental study of religion to defeat both radical freethinking and Calvinist orthodoxy. His work is another instance of the complicated relationship between science and religion within eighteenth-century Scotland. (shrink)

Working memory--the ability to keep important information in mind while comprehending, thinking, and acting--varies considerably from person to person and changes dramatically during each person's life. Understanding such individual and developmental differences is crucial because working memory is a major contributor to general intellectual functioning. This volume offers a state-of-the-art, integrative, and comprehensive approach to understanding variation in working memory by presenting explicit, detailed comparisons of the leading theories. It incorporates views from the different research groups that operate on each (...) side of the Atlantic, and covers working-memory research on a wide variety of populations, including healthy adults, children with and without learning difficulties, older adults, and adults and children with neurological disorders. A particular strength of this volume is that each research group explicitly addresses the same set of theoretical questions, from the perspective of both their own theoretical and experimental work and from the perspective of relevant alternative approaches. Through these questions, each research group considers their overarching theory of working memory, specifies the critical sources of working memory variation according to their theory, reflects on the compatibility of their approach with other approaches, and assesses their contribution to general working memory theory. This shared focus across chapters unifies the volume and highlights the similarities and differences among the various theories. Each chapter includes both a summary of research positions and a detailed discussion of each position. Variation in Working Memory achieves coherence across its chapters, while presenting the entire range of current theoretical and experimental approaches to variation in working memory. (shrink)

Many social scientists and philosophers have counted themselves moral relativists in some sense or other. We cannot deal with all the various views which are properly called forms of “moral relativism”; so I propose to explain a form of moral relativism which seems to me an interesting, and somewhat plausible theory. This theory comprises the following three affirmations: The basic moral principles of different individuals or groups sometimes are, or can be, in some important sense conflicting. When there is such (...) fundamental conflict of basic principles or standards, there is either always, or at least sometimes, no way to show that one view is better justified even in the presence of ideally complete factual information; in that sense the principles are equally justified or “valid.” But there is a sense in which a particular moral belief may be mistaken or unjustified, if it is a misapplication of the basic principles of the individual or group, e.g., if the basic principles plus statements of known or knowable facts entail a moral proposition incompatible with it. As stated, moral relativism could be true even though in fact, accidentally, all individuals agree in their basic moral principles. (shrink)

Implicit processes almost certainly preceded explicit processes in our evolutionary history, so they are likely to be more resistant to disruption according to the principles of evolutionary biology [Reber, A. S. . The cognitive unconscious: An evolutionary perspective. Consciousness and Cognition, 1, 93–133.]. Previous work . Knowledge, nerves and know-how: The role of explicit versus implicit knowledge in the breakdown of a complex motor skill under pressure. British Journal of Psychology, 83, 343–358.]) has shown that implicitly learned motor skills remain (...) stable under psychological pressure and concurrent cognitive demands, and recently [Poolton, J. M., Masters, R. S. W., & Maxwell, J. P. . Passing thoughts on the evolutionary stability of implicit motor behaviour: Performance retention under physiological fatigue. Consciousness and Cognition, 16, 456–468.] showed that they also remain stable under conditions of anaerobic fatigue that would have significantly challenged the survival skills of our ancestors. Here we examine the stability of an implicitly learned motor skill under fatigue conditions that primarily tax a different physiological system , but which have equally strong evolutionary connotations. Participants acquired a throwing task by means of an errorless learning method or an errorful method. Motor performance in the errorless condition, but not the errorful condition, remained stable following an exhaustive VO2 max. running test. Our findings replicate and extend the work of Poolton et al., providing further support for Reber’s evolutionary distinction between implicit and explicit processes. (shrink)

The famous 1893 Chicago World’s Fair celebrated the dawn of corporate capitalism and a new Machine Age with an exhibit of the world’s largest engine. Yet the noise was so great, visitors ran out of the Machinery Hall to retreat to the peace and quiet of the Japanese pavilion’s Buddhist temples and lotus ponds. Thus began over a century of the West’s turn toward an Asian aesthetic as an antidote to modern technology. From the turn-of-the-century Columbian Exhibition to the latest (...) Zen-inspired designs of Apple, Inc., R. John Williams charts the history of our embrace of Eastern ideals of beauty to counter our fear of the rise of modern technological systems. In a dazzling work of synthesis, Williams examines Asian influences on book design and department store marketing, the commercial fiction of Jack London, the poetic technique of Ezra Pound, the popularity of Charlie Chan movies, the architecture of Frank Lloyd Wright, and the design of the latest high-tech gadgets. Williams demonstrates how, rather than retreating from modernity, writers, artists, and inventors turned to traditional Eastern technê as a therapeutic means of living with—but never abandoning—Western technology. (shrink)

A conference celebrating the tercentenary of the publication of Leibniz’s Nouveau système will be held at the University of York, England, under the auspices of the Leibniz Gesellschaft of Hannover, and in collaboration with the British Society for the History of Philosophy, the Leibniz Society of North America, and the Lessico Intellettuale Europeo in Rome. Speakers will include R. M. Adams, S. Brown, G. Hartz, A. Lamarra, G. M. Ross, M. Mugnai, R. Palaia, G.H.R. Parkinson, P. Phemister, H. Poser, D. (...) Rutherford, C. Wilson. For further details contact Roger Woolhouse, Department of Philosophy, University of York, England Y01 5DD. (shrink)

Wnts are a recently described family of secreted glycoproteins related to the Drosophila segment polarity gene, wingless, and to the proto‐oncogene, int‐1. Wnts are thought to function as developmental modulators, with signalling distances of only a few cell diameters. In Xenopus, at least six Wnts, including Xwnts‐1, ‐3A, and ‐4, are expressed initially in the developing central nervous system, with some regions expressing multiple Xwnts. Xwnt‐8 is expressed by mid‐blastula stage, in ventral and lateral mesoderm. Xwnt‐5A mRNAs are stored in (...) the egg, and later are expressed throughout the embryo in both ectoderm and mesoderm, but with a pronounced enrichment in the head and tail. Recent studies in Xenopus have pursued the diverse roles of Xwnts in early development, the mechanisms by which Xwnts signal information between cells, and the cell physiological responses to Xwnt signals. (shrink)

The ontological argument of Saint Anselm, one of the most famous in the entire history of philosophy, has fascinated men’s minds for centuries. And yet, as Hartshorne makes abundantly clear, much of its subtlety has been missed by some of the keenest commentators. Although it has been discussed again and again, little work seems to have been done, even up to the moment, in exploring the logical forms or deep structures needed for an exact statement. Part of this is due (...) no doubt to the subtlety of the argument itself, but part of it is due to that fact that the key ideas involved are not of the kind that easily lend themselves to being handled within the standard kinds of logic. (shrink)

Yemeni writer Ahmed Qāsim al-Arīqī, in addition to his profession as a pharmacist, is a writer who has made a name for himself in the country's literary field, especially in the last fifteen years. A prolific writer, al-Arīqī is the author of poetry collections as well as stories and novels that emphasise awareness of the traditional issues of the Yemeni people. He has published "Maḳāmāt al-'Arīḳī" (2006), "Ġalṭṭetu Ḳalem" (2012), "Qurāt al-S̱-S̱elj" (2017), "Ta'riyya" (2018), "Zurbet al-Yumnā" (2018), "Da'wat al-Ḥuḳūl" (2019), (...) "Zuhr al-Ġarām" and "Sīret al-Kūbī" (2022). His novel "Yawma Māta al-Shaytan" (The Day Satan Died) was published electronically by Hindāwī Publishing House in 2022. The novel, which is approximately 120 pages, is written in six chapters. There are eleven passages in the first and fourth chapters, thirteen in the second and sixth chapters, twelve in the third chapter, and eight in the fifth chapter. The novel is about the adventures of a member of the army named Marwan Naji, who was wounded in the war between the Houthi militia and the Yemeni army, and after nine months in a coma, opens his eyes in a perfect world dominated by biological and technological advances. Symbolising the treatment of selfishness and various narcissisms with advanced vaccines through the death of Satan, the author describes Marwan's adventures in his world, which he sometimes describes as the realm of the jinn, in a very simple language, while not failing to criticise reality in its various political, social and religious dimensions. In fact, Marwan's world of imagination and fantasy is the main story of the novel, but not the only one. The author also includes the stories of family members in Marwan's world of turmoil, destruction, massacre, war and victory, giving the reader the opportunity to compare both worlds. While his mother Gusoun, his wife Hamide and his daughter Fatma, who later got engaged in time after being widowed, are the female characters of his real world, Professor Mari and Mariana, one of his seven wives, are the other important characters of his imaginary world. Gusûn is a devoted mother who does not leave the bedside of her comatose son, prays for him day and night and tries to do everything she can for his recovery. Gusûn, who is listened to at home to a certain extent, scolds her grandchildren to prevent the breakup of her son's home because of inheritance, defends that the existing wealth still belongs to her son and reminds them that she will not hesitate to spend money for his recovery. Gusûn's daughter-in-law Hamide also takes care of her husband, who shows no signs of recovery. Hamide, who is not as patient as her mother-in-law, is also a jealous woman. On the other hand, although both of them display false religious tendencies that have no relation with real life, Gusûn is more prone to the superstitious approaches put forward and adopted in the name of religion. Fatma is also a widow who, although she has the will to take care of her children and live her life alone, has been engaged for a long time to her uncle's son Münir, who, like her, took part in anti-regime demonstrations and whose love she believes in. Fatma, who is more conscious than her grandmother and mother, is not alien to the issues that society complains about and often participates in women's movements organised against the government. Professor Mari, one of the two important characters belonging to Marwan's imaginary world, is a psychologist and the chief physician of a large hospital who treats jealousy, anger, lying and selfishness, which are considered dangerous viruses, with vaccines developed by scientists. Professor Mari, who is personally involved in Marwan's treatment, also chairs the committee that records his memory and projects all his memories on a giant screen. Mariana, on the other hand, monitors Marwan's behaviour and thoughts through a biological chip to control the effect of the vaccines given to him, criticises him through the tragic images projected on the screen and provides information that will facilitate his adaptation to his new world. In the article, in which the author's main published works are briefly introduced along with a broad summary of the novel, the social messages that an author, who is not indifferent to the realities of the geography he lives in, tries to give directly and indirectly with a language far from locality, are tried to be determined through the mentioned female characters. It is seen that the desire to become a single nation by making; love, brotherhood, friendship and peace dominant lies behind the author's novelisation of the dream of an ideal world symbolised by the death of Satan. (shrink)

Anyone, today, with even a slight interest in the methodology of science will be aware of the heated debate which has raged in regard to the thesis of the logical symmetry between explanation and prediction, which is entailed by the hypotheticodeductive account of scientific theory. The symmetry thesis, which received its classical exposition in a well-known article by Hempel and Oppenheim [2], has been subject to a steadily growing criticism by several eminent thinkers. My intention, in this article, is to (...) argue that the current reaction to the Hempel-Oppenheim position, as exemplified by Professors Hanson, Scriven, et al., represents a retrograde movement in the philosophy of science, which, as the number of its converts grows, could undermine the progress, which has been accomplished in the broad tradition that extends from Mach and Poincaré through the Vienna Circle to the present day. Specifically, it is my contention that the aforementioned reaction is symptomatic of a contemporary trend in the direction of irrationalism which, of all branches of philosophy, the philosophy of science should seek to dispel rather than to foster. For the sake of brevity, I propose to focus my remarks wholly on the original widely read article of Hanson on this subject [1]. That I single out this particular source should not be taken to belie the admiration I hold for the masterful scholarship of its author. (shrink)