The overall trend toward globalization in design, greatly enhanced by digital technologies, has raised issues and challenges on how to preserve the cultural differences and values of different societies. There is a tendency to lose touch with local cultural values when designing artefacts for global use, and social nuances and traditions risk to be flattened or stereotyped in the pursuit of developing new technologies and products for the global society. Attempts to reduce the tension between the global and the local (...) in design can be seen in the development of standards and guidelines for cross-cultural design, that are mostly focused on user interface design. However, when moving from preferences, metaphors, appearance, and navigation toward cultural models of interaction and physical design, new methodologies and tools for cross-cultural design are needed. This paper describes a poetry-inspired design method for cross-cultural sharing within the design process. The approach uses poetry to sensitize the designer to the subtleties and diversity of a culture so that the design can be given new aesthetic and cultural significance. The methodology is exemplified by actual design cases developed within the course “Cultural Sensitivity” of the Master’s Degree Program in Industrial Design at Eindhoven University of Technology, where poetry was used for uncovering underlying or implicit assumptions, intercultural differences and similarities, as well as for general sensitization of young designers. (shrink)

O presente artigo tem por objetivo examinar a alienação que envolve a atividade do professor coordenador, relacionando esse profissional às expectativas do ideário neoliberal, reproduzido pela escola burguesa e comparar as atribuições destinadas a esse profissional com o seu fazer efetivo. O universo da pesquisa engloba a escola pública do Estado de São Paulo e a atividade do professor coordenador, especialmente as de Ciclo II. O referencial usado é o materialismo histórico dialético, e a categoria de análise é a teoria (...) da alienação, formulada por Marx e estudada por Mészáros. (shrink)

Carta escrita por Gilda de Mello e Souza, remetida ao colega Oswaldo Porchat, que se encontrava em Berkeley, quando a ditadura civil-militar brasileira, recrudescida desde a implantação, em agosto de 1968, do AI-5, representava uma verdadeira ameaça a estudantes e docentes da Universidade de São Paulo, especialmente se lhe fizessem qualquer tipo de oposição. Porchat trocou uma sequência de cartas com Gilda nessa época, nas quais relata sua desilusão com a Faculdade de Filosofia, e com os acontecimentos políticos no (...) Brasil. Ao mesmo tempo, confessa estar encantado com a descoberta de novos elementos da Lógica, e com a atmosfera mais amena dos Estados Unidos. Porchat sabe que Gilda enfrenta momentos difíceis, tendo de assumir a Presidência do curso em meio à tentativa do reitor Miguel Reale de submetê-lo a um interventor. Enfrentando a dúvida sobre se valeria a pena retornar ao Brasil naquele momento, Porchat escreve à amiga. A carta a seguir expressa, dentro do que era possível na época, quando as correspondências eram vigiadas, o parecer de Gilda sobre as indagações do amigo, sobre os rumos da ditadura, e sobre o que ela pensava de sua própria atitude de resistência naquele contexto. A carta original, assim como a sequência de correspondências da qual faz parte, está depositada no Fundo Gilda de Mello e Souza, no Instituto de Estudos Brasileiros (IEB/USP). Agradeço à família de Gilda, especialmente a Ana Luisa Escorel e a Laura Escorel, pela disponibilização desse documento para a presente publicação. (shrink)

In this review, we will focus on the role played by transcription factors of the E2F/DP family in controlling the expression of genes that carry out important cell‐cycle control functions, thereby ensuring ordered progression through the mammalian cell division cycle. The emerging picture is that cell‐cycle progression depends on the execution of a regulatory cascade of gene expression, driven by E2F/DP transcription factors, which are in turn regulated by the products of some of these genes. That E2F factors are potent (...) regulators of cell‐cycle checkpoints in mammalian cells is supported by experiments demonstrating that ectopic expression of individual E2F family members is sufficient to modulate cell proliferation and apoptosis. It is also clear that deregulation of E2F activity will result in the loss of particular checkpoint controls, thereby predisposing cells to malignant conversion. BioEssays 21:221–230. 1999. © 1999 John Wiley & Sons, Inc. -/- . (shrink)

O presente artigo tem por objetivo examinar a alienação que envolve a atividade do professor coordenador, relacionando esse profissional às expectativas do ideário neoliberal, reproduzido pela escola burguesa e comparar as atribuições destinadas a esse profissional com o seu fazer efetivo. O universo da pesquisa engloba a escola pública do Estado de São Paulo e a atividade do professor coordenador, especialmente as de Ciclo II. O referencial usado é o materialismo histórico dialético, e a categoria de análise é a teoria (...) da alienação, formulada por Marx e estudada por Mészáros. (shrink)

In Europe the elderly population is projected to increase from 18.5% (93.9 million) in 2014 to 28.7% (149.1 million) by 2080. In the USA it is estimated that by the year 2030 more than 20% of the population will be aged 65 years or over. This specific population is at high risk of unrecognised or untreated psychiatric illnesses and suicide. It is well known that completed suicide rate increases with age in both men and women. Although elderly people attempt suicide (...) less often than other age groups, they show a higher completion rate. Generally the methods chosen by elderly are more lethal, the intent is more serious, they are more determined and they show fewer warning sign than the younger population. A recent systematic review and meta-analysis of psychosocial intervention following self-harm in adults found that cognitive behavioural therapy was the most effective in these patients. Unfortunately there have been few reported trials of other potentially effective interventions. Because the scientific literature on psychosocial suicide prevention interventions in the elderly is still scant we decided to conduct a mini-review in order to take stock of the situation. Studies were identified through electronic searches of the Cochrane library, MEDLINE, Scopus and Web of Science databases. PRISMA guidelines were followed and only 7 articles met the inclusion criteria. No firm conclusions can be drawn about this topic because there is still little data and studies used inconsistent outcome measures and designs. Nonetheless, the existing data suggests that psychosocial interventions are promising. (shrink)

According to the principle known as “the principle of present-tense ascription immunity”, “It is impossible for anyone to have or entertain thoughts without being aware—immediately and self-evidently—that he is thinking that thought”. In other words, my thoughts are fundamentally experienced as mine, and I typically have this experience of mineness immediately, that is, without any inference based on evidence about who is the thinker of the thought. Thought insertion reveals instead that, under particular pathological conditions, people can be startlingly in (...) error about who is thinking a thought. How can this happen? In the attempt to specify how the capacity for self-ascription of a thought can.. (shrink)

Il saggio indaga il rapporto fra impresa e società fra ottocento e novecento così come si esprime nelle società per azioni e nelle imprese cooperative. Nella seconda metà dell’Ottocento i codici di commercio europei introducono la deregolamentazione delle public company e codificano per la prima volta l’impresa cooperativa. Entrambe le novità rappresentano una riposta ai problemi centrali di quella fase dello sviluppo industriale: il finanziamento delle iniziative economiche, la questione sociale e la governance dell’impresa. Si delineano così due forme di (...) impresa, la public company e l’impresa cooperativa, che per tutto il Novecento alimenteranno il dibattito sul rapporto fra società e impresa e contribuiranno alla crescita delle economie occidentali. (shrink)

Starting from the concept and definition of littera in the Grammar treatises of the Late Antiquity and the Early Middle Ages, the contribution analyzes common graphic elements which were used by the scribes to create initials, ornamental patterns and the layout of the manuscript page. These elements and their functions were partly described in encyclopaedic works, e. g. of Isidor of Sevilla and Martianus Capella in the chapters about Geometry. Not only were these features well known through the study of (...) the Artes, they also represented useful tools for the invention and production of medieval diagrams. (shrink)

According to a recent theory of the motivational content of self-deception, the self-deceiver wants to be in a state of mind of belief that p, upon which her want that p be true would be merely contingent. While I agree with Funkhouser that the self-deceiver is considerably moved by an interest in believing that p, which makes it possible for her to relate to reality in a highly prejudiced way, I will argue that it is unlikely that the self-deceiver’s primary (...) want to believe, or interest in believing that p occurs as the result of a merely contingent interest in p being true. I will finally assess various consequences of the view I favor, regarding the self-deceiver’s avoidance behaviour, “twisted” self-deception, and whether we should provide a unifying account of “straight” and “twisted” self-deception. (shrink)

John McDowell and Christine Korsgaard have defended the claim that when human beings judge or believe that p, they are exercising a fundamental kind of freedom, the “freedom of judging.” David Owens has challenged the view: he argues that they offer us at best no more than a modest notion of freedom, which does not vindicate the claim that we are free in many relevant instances of judgment, in particular in perceptual judgment. I argue that Owens is right if we (...) view the freedom of judgment along the lines of McDowell’s and Korsgaard’s proposals – as being a form of freedom which is describable as “freedom of choosing between alternatives,” but that that is not the only option available. In order to secure the nexus between reason and freedom, we can exploit a quite distinct model of freedom, which is the “freedom of autonomy.”. (shrink)