The high prevalence of cardiovascular diseases demands a reliable and sensitive risk assessment technique. In order to develop a fast and label-free immunosensor for C-reactive protein, a risk factor for this condition, anti-CRP antibodies were physically adsorbed to the hydrogen -terminated surface of nanocrystalline diamond. An Enzyme-Linked ImmunoSorbent Assay reference technique showed that this was a suitable substrate for antibody-antigen recognition reactions. Electrochemical Impedance Spectroscopy was used to electronically detect CRP recognition. The specificity of the immunosensor was demonstrated by incubation (...) with CRP and plasminogen as reference molecule. A different impedance behavior was observed in real-time after CRP addition as compared to plasminogen addition: the impedance increased only during CRP incubation. Fitting the data showed that this corresponded with a decrease in capacitance of the molecular layer due to its increased thickness by specific CRP recognition. Sensitivity experiments in real-time showed a clear discrimination between 1 μM, 100 nM, and 10 nM of CRP after 10 min at 100 Hz. Since, 10 nM of CRP was still clearly distinguishable from buffer solution, our CRP-directed immunosensor prototype reaches a sensitivity that is within the physiologically relevant concentration range of this biomarker in healthy controls and CVD patients. Moreover, this prototype displayed real-time discriminating power between spiked and unspiked serum, and thus also shows its applicability in this biological matrix. © 2011 Elsevier B.V. All rights reserved. (shrink)

Antik Mısır’da Meryem isminin yazılışı mr sözcüğüyledir, sevilen anlamına gelir. İsis de Meryem de, özü itibarıyla aynı Tanrıça olduğu gibi Tanrısal ananın aynı bedenleşmiş görünümüdür. Bu nedenle, Hıristiyanlar, İsis’in tapınaklarını yıkıp yerle bir etmişler ve tapınanlarını da öldürmüşler; fakat bütün bu olup bitenlere rağmen, İsis, Meryem’e beslenilen iman ve tapınmada yaşamaya devam etmiştir. Nitekim İsis’e okyanus yıldızı anlamına gelen “Pelagia” unvanı verilmişken, benzeri şekilde Meryem de denizyıldızı olarak tanınmıştır. İştar ya da İnanna’nın tanındığı unvanlar gibi, Meryem de İsis’e verilen “Göğün (...) Kraliçesi” unvanını paylaşmıştır. İsis, Tanrıça konumuyla her şeyin hükmedicisini yansıtırken; Meryem de, Kutsal Ruh ya da Tanrı ailesi olarak eşleştirilen gökteki yücelmeyi ve taçlanmayı temsil etmektedir. (shrink)

Gustav Aulen's starting point in this book is that God can only reveal himself in the form of symbols; in himself he remains beyond our comprehension. The symbols we use will determine our image of God. A bewildering variety of such images is to be found in modern literature, but the Christian image of God is inseparably linked with the drama of Christ.

The role and attitude of the faculty members, who is one of the pillars of the education system, is important in making the evaluation of distance education, which began to be implemented quickly and suddenly with the pandemic process. For this purpose, the effects of the use of distance education in higher religious education were examined from the perspective of the faculty members. 134 faculty members working in faculty of theology/Islamic sciences participated in the research. In the research, the descriptive (...) survey model, one of the quantitative research methods, was used. The data of the study was collected with a survey form consisting of 40 items in the five-point Likert type as well as demographic information. The analysis were made with SPSS 26 program using frequency (f), percentage (%) and mean (x̄) calculations from descriptive statistical methods. The findings in the dimensions of technology use and the role of the distance education support unit, preparation for lessons and motivation, teaching process and general evaluation of the method are presented in tables and interpreted. As a result, it was revealed that the anxiety and worry in the first stage decreased in the faculty members, they could adapt themselves to the distance education method sufficiently, but they were not satisfied with the efficiency of the courses, the attendance rates of the students, the assessment and evaluation methods used. The integration of distance education, which was found to be quite inadequate especially in achievements of applied courses, could not be fully achieved in the theology/Islamic sciences faculty programme. It can be said that the negative attitude towards distance education, which is evaluated as in the position of supporting traditional education, may change with the improvement works to be carried out. (shrink)