Binge-purge eating disorders (BP-ED), such as bulimia nervosa and binge eating disorder, may share some neurobiological features. Electroencephalography (EEG) is a non-invasive measurement modality that may aid in research and diagnosis of BP-ED. We conducted a systematic review of the literature on EEG findings in BP-ED, seeking to summarize and analyze the current evidence, as well as identify shortcomings and gaps to inform new perspectives for future studies. Following PRISMA Statement recommendations, the PubMed, Embase, and Web of Science databases were (...) searched using terms related to “electroencephalography” and “binge-purge” eating disorders. Of 555 articles retrieved, 15 met predefined inclusion criteria and were included for full-text analysis. Eleven studies investigated EEG by means of event-related potentials (ERP) in BP-ED individuals: 7 using eating disorder-related stimuli (i.e., food, body image) and 4 using non-eating disorder-related stimuli (i.e., facial expressions or auditory clicks). These studies found significant differences in the N200, P200, P300, and LPP components in BP-ED participants compared to controls, indicating that this population exhibits impairments in selective attention, attentional allocation/processing, and allocation of motivational or emotion-based attention. Five studies investigated EEG using frequency analysis; reporting significant differences in beta activity in fronto-temporal and occipito-temporo-parietal areas in BP-ED individuals compared to controls, revealing a dysfunctional brain network. However, the small number of studies, the heterogeneity of samples, study paradigms, stimulus types, and the lack of an adequate assessment of neuropsychological parameters are some limitations of the current literature. Although some EEG data are promising and consistent with neuroimaging and neuropsychological findings in individuals with BP-ED, future studies need to overcome current methodological shortcomings. (shrink)

The increasing use of cluster randomised trials in low-resource settings raises unique ethical issues. TheOttawa Statement on the Ethical Design and Conduct of Cluster Randomised Trialsis the first international ethical guidance document specific to cluster trials, but it is unknown if it adequately addresses issues in low-resource settings. In this paper, we seek to identify any gaps in theOttawa Statementrelevant to cluster trials conducted in low-resource settings. Our method is (1) to analyse a prototypical cluster trial conducted in a low-resource (...) setting (PURE Malawi trial) with theOttawa Statement; (2) to identify ethical issues in the design or conduct of the trial not captured adequately and (3) to make recommendations for issues needing attention in forthcoming revisions to theOttawa Statement. Our analysis identified six ethical aspects of cluster randomised trials in low-resource settings that require further guidance. The forthcoming revision of theOttawa Statementshould provide additional guidance on these issues: (1) streamlining research ethics committee review for collaborating investigators who are affiliated with other institutions; (2) the classification of lay health workers who deliver study interventions as health providers or research participants; (3) the dilemma experienced by investigators when national standards seem to prohibit waivers of consent; (4) the timing of gatekeeper engagement, particularly when researchers face funding constraints; (5) providing ancillary care in health services or implementation trials when a routine care control arm is known to fall below national standards and (6) defining vulnerable participants needing protection in low-resource settings. (shrink)

Estudos indicam que o estresse altera o sistema imune e pode influir na etiologia, progressão e severidade de doenças. A resiliência pode ser definida como a capacidade que algumas pessoas desenvolvem e as ajudam a passar por situações adversas na vida, a superá-las, e ainda a saírem fortalecidas ou..

Over one-third of the white working class in America vote for Republicans. Some scholars argue that these voters support Republican economic policies, while others argue that these voters’ preferences on cultural and moral issues override their economic preferences. We draw on in-depth interviews with 120 white working-class voters to defend a broadly “economic” interpretation: for this segment of voters, moral and cultural appeals have an economic dimension, because these voters believe certain moral behaviors will help them prosper economically. Even the (...) very word “conservative” is understood as referencing not respect for tradition generally, but avoidance of debt and excessive consumption specifically. For many respondents, the need to focus on morality and personal responsibility as a means of prospering economically—what we call “walking the line”—accords with the rhetoric they associate with Republicans. Deindustrialization may have heightened the appeal of this rhetoric. (shrink)

Key messages The research environment has changed since clinical equipoise was first proposed 30 years ago New trial designs—such as umbrella and basket trials, adaptive platform trials, and cluster randomised trials—raise new ethical challenges for evaluating the state of scientific uncertainty and communicating about risks with patients and participants Clinical equipoise needs to evolve We propose the design of specific guidelines to provide ethics committees and trialists with instructions for how to evaluate equipoise in the context of new designs and (...) biomarkers and how to optimise communication with participants. (shrink)

Aaron Lustiger naît à Paris le 17 septembre 1926. Ses parents sont venus de Pologne et tiennent un magasin de bonneterie, d’abord à Montmartre, puis à Montparnasse. Le jeune Aaron découvre seul la Bible alors qu’il est élève au lycée Montaigne, et l’antisémitisme nazi à l’occasion de séjours linguistiques en Allemagne.Lorsqu’éclate...

Aborder l’histoire des mathématiques et son enseignement à travers les institutions scientifiques est une démarche dorénavant courante et souvent pertinente. De nombreux travaux l’ont montré en particulier dans le cadre des grandes institutions scientifiques militaires comme l’École polytechnique [Belhoste 1994], [Bret 2002]. L’histoire de l’enseignement et de la diffusion des sciences, en particulier des mathématiques, a été renouvelée depuis une vingtaine d’années tant en France que dans d’...

The enthusiasm for research in an Indigenous context has led to the introduction of formal guidelines for researchers to visit communities. While welcome, this has not been achieved without increased bureaucratization of research relationships. It appears that many Indigenous communities, with their limited resources, are ill-equipped to deal with the administrative imperatives of Indigenous research protocols. Based on the experiences of anthropological field research in the Innu context, this article shows how respectful research relationships could be established outside the bureaucratic (...) and administrative framework generally advocated by research protocols. The heart of this approach lies in the researcher’s radical participation in social life, and more specifically in taking seriously the social premises of the people with whom he works. The mistake would be to think that this collaborative approach is situated in informality: rather, it takes place within an eminently formal framework that corresponds to the criteria and values of the researcher’s Indigenous collaborators. (shrink)

La violencia de pareja hacia las mujeres es un problema de salud de primer orden con graves repercusiones para la salud física y mental de las víctimas y de los conviventes, y de esta forma ha sido recogido por las principales organizaciones con competencias en salud.

Abstractabstract:This article analyzes Claude McKay's last novel, Amiable with Big Teeth—recently discovered in 2017—as a piece of postcolonial utopianist writing. The novel participates in an important debate on the role of utopias and utopian writing as ideological mechanisms that perpetuate colonial structures such as the nation-state. Through a critique of the Popular Front project in the black community of 1930s Harlem, Amiable with Big Teeth vindicates local knowledges and the assessment of the specific conditions of the present—ever-changing and transformable—in the (...) development of strategies for resistance. As such, the spiritual role of Ethiopia for the community depicted, rather than constitute yet another national utopia, fulfills the same role as it did for the Jamaican Rastafarians: it is a mechanism for group self-assertion and the promotion of self-esteem that subaltern communities need in order to achieve full agency. (shrink)

This work examines thoughtlessness and seeks to illuminate the necessity and extent that reflection is involved in becoming practically wise within an Aristotelian virtue ethical framework. Derived from an Arendtian reading of Kantian aesthetic judgment, an account of thinking and judging is offered to supplement traditional accounts of practical wisdom.

An investigation of ways in which man violates the animal world and examination of role played by various societies throughout the world in protection of animals.

This paper highlights alternative responsible business models with an outspoken and profound dedication to contribute to a sustainable development. Themarket of alternatives and their networking activities to make the alternative market grow will be discussed in terms of programs and anti-programs. Another issue brought up is their ability to stick to the responsible knitting, as they grow and develops in a capitalistic market surrounding.

El objetivo de este estudio es mostrar el sentir de los estudiantes de licenciatura durante la contingencia sanitaria. Se realizó un estudio cualitativo a través de la narrativa de 35 estudiantes. Los principales resultados muestran que éstos se enfrentaron a diversos sentimientos y retos en su aprendizaje a lo largo de casi dos años de confinamiento.

Ethical leadership matters in the context of organizational change due to the need for followers to trust the integrity of their leaders. Yet, there have been no studies investigating ethical leadership and organizational change. To fill this gap, we introduce a model of the moderating role of involvement in change. Organizational change and involvement in change are proposed as context-level moderators in the relationships of ethical leadership and work-related attitudes and performance. We employ a sample of 199 supervisor–subordinate pairs from (...) a wide variety of organizations. Results support a three-way interaction (ethical leadership, organizational change, and involvement in change) for performance and OCBs. Our results have important implications for organizational change since ethical leadership appears to complement follower involvement when change is happening. (shrink)

This paper is about syllogistic reasoning, i.e., reasoning from such pairs of premises as, All the chefs are musicians; some of the musicians are painters. We present a computer model that implements the latest account of syllogisms, which is based on the theory of mental models. We also report four experiments that were designed to test this account. Experiments 1 and 2 examined the strategies revealed by the participants' use of paper and pencil as aids to reasoning. Experiment 3 used (...) a new technique to externalize thinking. The participants had to refute, if possible, putative conclusions by constructing external models that were examples of the premises but counterexamples of the conclusions. Experiment 4 used the same techniques to examine the participants' strategies as they drew their own conclusions from syllogistic premises. The results of the experiments showed that individuals not trained in logic can construct counterexamples, that they use similar operations to those implemented in the computer model, but that they rely on a much greater variety of interpretations of premises and of search strategies than the computer model does. We re‐evaluates current theories of syllogistic reasoning in the light of these results. (shrink)

Understanding what it means toconsent is of considerable importance sincesignificant moral issues depend on how this actis defined. For instance, determining whetherconsent has occurred is the deciding factor insexual assault cases; its proper occurrence isa necessary condition for federally fundedhuman subject research. Even though mosttheorists recognize the legal and moralimportance of consent, there is still littleagreement concerning how consent should bedefined, or whether different domains involvingconsent demand context-specific definitions.Understanding what it means to consent isfurther complicated by the fact that currentlegal (...) conceptions are not necessarily groundedin argument; they typically depend on appealsto authority and precedent. The purpose ofthis paper is to use speech act theory toprovide a theoretically grounded conception ofconsent; such a conception can aid in the justresolution of legal and moral disputes thathinge on whether an act of consent occurred. (shrink)

Na sociedade definida por Bauman como líquida, manter o foco no trabalho em equipe para o sucesso das organizações parece ser tarefa cada vez mais fluida. Discutir esse quadro é a proposta deste artigo, que apresenta exemplos de situações éticas desafiadoras no ambiente corporativo, como o medo, a rotina, a flexibilidade, o fracasso, os riscos, o coletivo. Para tanto, o texto aborda a imagem organizacional e os valores associados a ela e que podem ajudar a construir um significado positivo ou (...) negativo. Considera-se também a opinião de profissionais com experiência em gestão. (shrink)

En este ensayo se reflexiona sobre el sentido de la interpretación nietzscheana de Grecia, que aunque problemática y filosófica, se inserta en la tradición clasicista de Occidente. Ubicando el clima intelectual en el que surgió El nacimiento de la tragedia, se postula que el pensador alemán no puede..

In a process of emancipatory collective education proposed by the Urban Boundaries Project, this paper discusses the importance of the educational process not as cloistered but as critical tool to the current hegemonic system, and thus its roots in our situationality, as well as in our relations of survival. The concept of love as a political category will be argued from the modes of production of the urban human beings and its relations among the productive forces, the relations of production, (...) and the conscious bodies. Disturbing choices made in the dialogical exercise, from a victimization posture to a free collective subject rooted in or identified with a particular form of life, supports this argument. (shrink)