Keller & Miller's (K&M's) conclusion appears to be correct; namely, that common, harmful, heritable mental disorders are largely maintained at present frequencies by mutation-selection balance at many different loci. However, their “paradox” is questionable. (Published Online November 9 2006).

In his paper ``What is Structural Realism?'' James Ladyman drew a distinction between epistemological structural realism and metaphysical (or ontic) structural realism. He also drew a suggestive analogy between the perennial debate between substantivalist and relationalist interpretations of spacetime on the one hand, and the debate about whether quantum mechanics treats identical particles as individuals or as `non-individuals' on the other. In both cases, Ladyman's suggestion is that an ontic structural realist interpretation of the physics might be just what is (...) needed to overcome the stalemate. The main thesis of this paper is that, whatever the interpretative difficulties of generally covariant spacetime physics are, they do not support or suggest structural realism. In particular, I hope to show that there is in fact no analogy that supports a similar interpretation of the metaphysics of spacetime points and of quantum particles. (shrink)

While many philosophers of science have accorded special evidential significance to tests whose results are "novel facts", there continues to be disagreement over both the definition of novelty and why it should matter. The view of novelty favored by Giere, Lakatos, Worrall and many others is that of use-novelty: An accordance between evidence e and hypothesis h provides a genuine test of h only if e is not used in h's construction. I argue that what lies behind the intuition that (...) novelty matters is the deeper intuition that severe tests matter. I set out a criterion of severity akin to the notion of a test's power in Neyman-Pearson statistics. I argue that tests which are use-novel may fail to be severe, and tests that are severe may fail to be use-novel. I discuss the 1919 eclipse data as a severe test of Einstein's law of gravity. (shrink)

The growing availability of computer power and statistical software has greatly increased the ease with which practitioners apply statistical methods, but this has not been accompanied by attention to checking the assumptions on which these methods are based. At the same time, disagreements about inferences based on statistical research frequently revolve around whether the assumptions are actually met in the studies available, e.g., in psychology, ecology, biology, risk assessment. Philosophical scrutiny can help disentangle 'practical' problems of model validation, and conversely, (...) a methodology of statistical model validation can shed light on a number of issues of interest to philosophers of science. (shrink)

In ____Womanizing Nietzsche,__ Kelly Oliver uses an analysis of the position of woman in Nietzsche's texts to open onto the larger question of philosophy's relation to the feminine and the maternal. Offering readings from Nietzsche, Derrida, Irigaray, Kristeva, Freud and Lacan, Oliver builds an innovative foundation for an ontology of intersubjective relationships that suggests a new approach to ethics.

In the first part of this paper a relational account of incongruent counterparts is defended against an argument due to Kant. I then consider a more recent attack on such an account, due to John Earman, which alleges that the relationalist cannot account for the lawlike left--right asymmetry manifested in parity-violating phenomena. I review Hoefer's, Huggett's and Saunders' responses to Earman's argument and argue that, while a relationalist account of parity-violating laws is possible, it comes at the cost of non-locality.

Current scientific research almost always requires collaboration among several (if not several hundred) specialized researchers. When scientists co-author a journal article, who deserves credit for discoveries or blame for errors? How should scientific institutions promote fruitful collaborations among scientists? In this book, leading philosophers of science address these critical questions.

Paulo Freire : the educator, his oeuvre, and changing contexts -- Holistic interpretations of Freire's work : a critical review -- Critical literacy, praxis, and emancipatory politics -- "Remaining on the same side of the river" : neo-liberalism, party movements, and the struggle for greater coherence -- Reinventing Freire in a Southern context : the Mediterranean -- Engaging with practice : a Freirean reflection on different pedagogical sites.

Family Values shows how the various contradictions at the heart of Western conceptions of maternity and paternity problematize our relationships with ourselves and with others. Using philosophical texts, psychoanalytic theory, studies in biology and popular culture, Kelly Oliver challenges our traditional concepts of maternity which are associated with nature, and our conceptions of paternity which are embedded in culture. Oliver's intervention calls into question the traditional image of the oppositional relationship between nature and culture, maternal and paternal. Family (...) Values also undercuts recent returns to the rhetoric of a "battle between the sexes" by analyzing the conceptual basis of these descriptions in biological research and the presuppositions of such suggestions in philosophy and psychoanalysis. By developing a reconception of maternity and paternity, Family Values offers hope for peace in the battle of the sexes. (shrink)

In Subjectivity without Subjects, well-known philosopher and feminist theorist Kelly Oliver looks at aspects of popular culture, film, science, and law to examine contemporary notions of paternity and maternity. Oliver studies the roles of paternal responsibility, virility, and race in such events as the Million Man March and the Promise Keeper's movement and suggests alternative ways to conceive of self-other relations and the subjective identity at stake in them. In addition she offers a detailed analysis of particular works (...) by such well-known filmmakers as Polanski, Bergman, and Varda in developing a theory of identity that opens the subject to otherness and difference. (shrink)

Over the past two decades, several consistent procedures have been designed to infer causal conclusions from observational data. We prove that if the true causal network might be an arbitrary, linear Gaussian network or a discrete Bayes network, then every unambiguous causal conclusion produced by a consistent method from non-experimental data is subject to reversal as the sample size increases any finite number of times. That result, called the causal flipping theorem, extends prior results to the effect that causal discovery (...) cannot be reliable on a given sample size. We argue that since repeated flipping of causal conclusions is unavoidable in principle for consistent methods, the best possible discovery methods are consistent methods that retract their earlier conclusions no more than necessary. A series of simulations of various methods across a wide range of sample sizes illustrates concretely both the theorem and the principle of comparing methods in terms of retractions. (shrink)

Was the zoological garden a place for science in the 19th and 20th centuries? This question cannot be answered with a simple yes or no. Rather, this Special Issue suggests, we need to reconstruct how the concrete conditions of the zoo as an institution influenced, enabled, triggered, facilitated, obstructed, or impeded scientific research. The zoo was and is a multifunctional space serving different constituencies, such as scientists of different disciplines, artists, breeders, and the general public. This collection of articles argues (...) that despite or even because of its hybrid character, the zoo generated knowledge about exotic animals in often unexpected ways. This Special Issue conceives of “science at the zoo” as a an “impure,” yet very rich epistemic constellation with its very own dynamic, tensions, and contradictions. The first part of this introduction provides a historical overview of the topic. Synthesizing the existing secondary literature, it addresses the major themes of science at the zoo: the debate among scientists about the pros and cons of research conducted in and outside the cages; the gap between the promise of doing research at the zoo and the actual practices; and the emergence of new fields of knowledge such as zoo veterinary medicine, zoo biology, and conservation science. The introduction's second part draws out the common topics that connect the eight articles of this Special Issue: the multiplicity of spaces interacting with the zoo; the broad range of historical actors, including academics, animal traders, and zoo keepers; the changing roles of the zoo-going public; and the negotiation of authority and epistemic hierarchies in producing knowledge about zoo animals. The large numbers of zoos and the long temporal range these articles cover bring the constant evolution of “science at the zoo”-and hence its intrinsic historical dimension-to the fore. (shrink)

Ontologies, as the term is used in informatics, are structured vocabularies comprised of human- and computer-interpretable terms and relations that represent entities and relationships. Within informatics fields, ontologies play an important role in knowledge and data standardization, representation, integra- tion, sharing and analysis. They have also become a foundation of artificial intelligence (AI) research. In what follows, we outline the Coronavirus Infectious Disease Ontology (CIDO), which covers multiple areas in the domain of coronavirus diseases, including etiology, transmission, epidemiology, pathogenesis, diagnosis, (...) prevention, and treatment. We emphasize CIDO development relevant to COVID-19. (shrink)

In this article, the authors highlight connections between research on Two Spirit Native Americans and standard social studies curriculum. Two Spirit is a Pan-Indian term describing Native Americans who believe they embody both masculine and feminine characteristics/traits in one physical body. Findingsfrom this research expand the field's conception of multiple perspectives and diversity, while creating opportunities for nuanced understandings of genderexpression and gender that go beyond the male/female dichotomy currently accepted as the norm. The authors utilize historical research and a (...) semi-structured,in-depth interview with a current Ojibwe leader to better understand and theorize Native Americans' acceptance of diverse ways of being. The authors conclude that modern-day social studies teachers and students have much to learn from this traditional Native worldview. Specifically, the authors believe that encouraging students to adopt more inclusive perspectives on gender expression and to recognize the plausibility of multiple genders may lead to more advanced, social learning. Combined with reinforcement from responsible adults at school, this recognition would lessen a variety of present-day social ills, including the incidence of teen suicide caused by homophobia. (shrink)

In Philosophical Problems of Statistical Inference, Seidenfeld argues that the Neyman-Pearson (NP) theory of confidence intervals is inadequate for a theory of inductive inference because, for a given situation, the 'best' NP confidence interval, [CIλ], sometimes yields intervals which are trivial (i.e., tautologous). I argue that (1) Seidenfeld's criticism of trivial intervals is based upon illegitimately interpreting confidence levels as measures of final precision; (2) for the situation which Seidenfeld considers, the 'best' NP confidence interval is not [CIλ] as Seidenfeld (...) suggests, but rather a one-sided interval [CI0]; and since [CI0] never yields trivial intervals, NP theory escapes Seidenfeld's criticism entirely; (3) Seidenfeld's criterion of non-triviality is inadequate, for it leads him to judge an alternative confidence interval, [CI alt. ], superior to [CIλ] although [CI alt. ] results in counterintuitive inferences. I conclude that Seidenfeld has not shown that the NP theory of confidence intervals is inadequate for a theory of inductive inference. (shrink)

The images from wars in the Middle East that haunt us are those of young women killing and torturing. Their media circulated stories share a sense of shock. They have both galvanized and confounded debates over feminism and women's equality. And, as Oliver argues in this essay, they share, perhaps subliminally, the problematic notion of women as both offensive and defensive weapons of war, a notion that is symptomatic of fears of women's “mysterious” powers.

We argue that a responsible analysis of today's evidence-based risk assessments and risk debates in biology demands a critical or metascientific scrutiny of the uncertainties, assumptions, and threats of error along the manifold steps in risk analysis. Without an accompanying methodological critique, neither sensitivity to social and ethical values, nor conceptual clarification alone, suffices. In this view, restricting the invitation for philosophical involvement to those wearing a "bioethicist" label precludes the vitally important role philosophers of science may be able to (...) play as bioevidentialists. The goal of this paper is to give a brief and partial sketch of how a metascientific scrutiny of risk evidence might work. (shrink)

This book offers a critical Arabic edition, annotated English translation, introductory study, and two-way glossaries of a pharmacological masterpiece composed around the middle of the 12th century CE in Baghdad by the Nestorian physician Ibn at-Tilmīḏ.

This book offers an Arabic edition, English translation, study and glossaries of ʿUbaidallāh Ibn Buḫtīšūʿ’s important work on apparent death; an appendix moreover provides the Arabic and Hebrew recensions of ʿUbaidallāh’s lost Greek _Vorlage_.

The paper is a combination of criticism and defense of ethical intuitionism, Meaning by this the view that we have insights about such matters that we can know to be true. Although the thesis is accepted that intuition is an authentic source of ethical knowledge, Many of the claims of intuitionists are subjected to critical scrutiny.

This article focuses on the structures of humor and joke telling that require particular kinds of attentiveness and particular relationships between speaker and audience, or more specifically, between classmates. First, I will analyze the pedagogical and relational preconditions that are necessary for humor to work. If humor is to work well, the person engaging in humor needs to gauge their interlocutors carefully. I discuss, too, the kinds of listening necessary for listening for the joke, including attentiveness to complex possibilities for (...) meaning. This attentiveness to complexity is linked to curiosity and a willingness to be startled, two qualities that are central to the risk and pleasure of learning discussed by Socrates and Maria Lugones. Examining the place of risk in Socrates’ teaching and the place of serious play in Maria Lugones’ discussion of difference, I suggest that humor can help to illuminate complicities and invite more robust interactions with difference, creating pleasurable encounters to work through difficult social divisions. (shrink)

‘Moral Integrity’ has struck me for some time as one of those things that is more a matter of name-dropping than of real acquaintance. But when I undertook to say something about it, I soon discovered that I had bitten off far more than I – or perhaps anyone – could chew within the hour. In this I find myself in good company: for Professor Winch also chose this title for his Inaugural Lecture – I apologise for overlooking this when (...) I chose my own title – and in his first paragraph he explains that he will be saying nothing about Moral Integrity, though he expresses the hope that what he has said will be found to have a bearing on it. I shall not be discussing his lecture, except incidentally; but I commend his wisdom in not trying, as rashly as I am, to say something directly about the topic. (shrink)

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In medicine and the social sciences, researchers often measure only a handful of variables simultaneously. The underlying assumption behind this methodology is that combining the results of dozens of smaller studies can, in principle, yield as much information as one large study, in which dozens of variables are measured simultaneously. Mayo-Wilson :864–874, 2011, Br J Philos Sci 65:213–249, 2013. https://doi.org/10.1093/bjps/axs030) shows that assumption is false when causal theories are inferred from observational data. This paper extends Mayo-Wilson’s results to (...) cases in which experimental data is available. I prove several new theorems that show that, as the number of variables under investigation grows, experiments do not improve, in the worst-case, one’s ability to identify the true causal model if one can measure only a few variables at a time. However, stronger statistical assumptions significantly aid causal discovery in piecemeal inquiry, even if such assumptions are unhelpful when all variables can be measured simultaneously. (shrink)

Los sistemas políticos democráticos están atravesando un período de fuertes convulsiones. A partir del análisis de dos casos de estudio de Comunidades de Creación Online (CCOs), como formas pensadas e implementadas en y desde Internet, el artículo presenta algunas conclusiones sobre las características específicas de la participación y la agencia política que puedan resultar generalizables en un proceso de transformación profunda de la democracia contemporánea. Los casos de estudio son el proyecto de memoria viva del Foro Social Europeo y Wikipedia.

Bernard Mayo; XII*—A Correspondence Theory of Value, Proceedings of the Aristotelian Society, Volume 73, Issue 1, 1 June 1973, Pages 181–192, https://doi.org/10.

The notion of »the problematic« has changed its meaning within the history of power and knowledge since the early 20th century, leading up to today's performative, neocybernetic fascination with generalized management ideas and technocratic models of science. This book explores central scenes, conceptual elaborations, and practical affiliations of what historically has been called »the problem« or »the problematic«. By way of considering modes of problematization as modes of inhabitation, intervention, and transformation the contributions map its current conceptual-political uses as well (...) as onto-epistemological challenges. Thus, »problematization« is positioned as a critical concept that links, often in intricate ways, several currents from speculative philosophy to the formation of interdisciplinary fields. The »problematic«, as it turns out, has been the source of change in philosophy and the sciences all along. (shrink)