Background: Frailty is a common syndrome among older adults and patients with several comorbidities. Grip strength is a representative parameter of frailty because it is a valid indicator of current and long-term physical conditions in the general population and patients with severe mental illnesses. Physical and cognitive capacities of people with SMIs are usually impaired; however, their relationship with frailty or social functioning have not been studied to date. The current study aimed to determine if GS is a valid predictor (...) of changes in cognitive performance and social functioning in patients with type-2 diabetes mellitus and SMIs. Methods: Assessments of social functioning, cognitive performance, and GS were conducted in 30 outpatients with type 2 diabetes mellitus, 35 with major depressive disorder, 42 with bipolar disorder, 30 with schizophrenia, and 28 healthy controls, twice during 1-year, follow-up period. Descriptive analyses were conducted using a one-way analysis of variance for continuous variables and the chi-squared test for categorical variables. Differences between groups for the motor, cognitive, and social variables at T1 and T2 were assessed using a one-way analysis of covariance, with sex and age as co-variates. To test the predictive capacity of GS at baseline to explain the variance in cognitive performance and social functioning at T2, a linear regression analysis was performed. Results: Predictive relationships were found among GS when implicated with clinical, cognitive, and social variables. These relationships explained changes in cognitive performance after one year of follow-up; the variability percentage was 67.7%, in patients with type-2 diabetes mellitus and 89.1% in patients with schizophrenia. Baseline GS along with other variables, also predicted changes in social functioning in major depressive disorder, bipolar disorder, and schizophrenia, with variability percentages of 67.3, 36, and 59%, respectively. Conclusion: GS combined with other variables significantly predicted changes in cognitive performance and social functioning in people with SMIs or type-2 diabetes mellitus. Interventions aimed to improve the overall physical conditions of patients who have poor GS could be a therapeutic option that confers positive effects on cognitive performance and social functioning. (shrink)

Many theorists have dismissed a priori the idea that distributional information could play a significant role in syntactic category acquisition. We demonstrate empirically that such information provides a powerful cue to syntactic category membership, which can be exploited by a variety of simple, psychologically plausible mechanisms. We present a range of results using a large corpus of child‐directed speech and explore their psychological implications. While our results show that a considerable amount of information concerning the syntactic categories can be obtained (...) from distributional information alone, we stress that many other sources of information may also be potential contributors to the identification of syntactic classes. (shrink)

Psychologists and philosophers have assumed that psychological knowledge is knowledge about, and held by, the individual mind. _Psychological Knowledge_ challenges these views. It argues that bodies of psychological knowledge are social institutions like money or the monarchy, and that mental states are social artefacts like coins or crowns. Martin Kusch takes on arguments of alternative proposals, shows what is wrong with them, and demonstrates how his own social-philosophical approach constitutes an advance. We see that exists a substantial natural amount (...) of philosophical theorising, a body of work that tries to determine the nature and structure of folk psychology. An introduction to the workings of constuctivism, _Psychological Knowledge_ is an insightful introduction to the history of psychology and the recent philosophy of mind. (shrink)

How do people excluded from political life achieve political agency? Through a series of historical events that have been mostly overlooked by political theorists, Martin Breaugh identifies fleeting yet decisive instances of emancipation in which people took it upon themselves to become political subjects. Emerging during the Roman plebs's first secession in 494 BCE, the _plebeian experience_ consists of an underground or unexplored configuration of political strategies to obtain political freedom. The people reject domination through political praxis and concerted (...) action, therefore establishing an alternative form of power. Breaugh's study concludes in the nineteenth century and integrates ideas from sociology, philosophy, history, and political science. Organized around diverse case studies, his work undertakes exercises in political theory to show how concepts provide a different understanding of the meaning of historical events and our political present. _The Plebeian Experience_ describes a recurring phenomenon that clarifies struggles for emancipation throughout history, expanding research into the political agency of the many and shedding light on the richness of radical democratic struggles from ancient Rome to Occupy Wall Street and beyond. (shrink)

The paper defends the permissibility of paying inducements to research subjects against objections not covered in an earlier paper in Bioethics. The objections are that inducements would cause inequity, crowd out research, and undesirably commercialize the researcher‐subject relationship. The paper shows how these objections presuppose implausible factual and/or normative claims. The final position reached is a qualified defence of freedom of contract which not only supports the permissibility of inducements but also offers guidance to ethics committees in dealing with practical (...) problems that might arise if inducements are offered. (shrink)

Today, human pluripotent stem cell technologies find widespread application across biomedical research, as models for early human development, as platforms for functional human genomics, as tools for the study of disease, drug screening and toxicology, and as a renewable source of cellular therapeutics for a range of intractable diseases. The foundations of this human pluripotent stem cell revolution rest on advances in a wide range of disciplines, including cancer biology, assisted reproduction, cell culture and organoid technology, somatic cell nuclear transfer, (...) primate embryology, single‐cell biology, and gene editing. This review surveys the slow emergence of the study of human pluripotency and the exponential growth of the field during the past several decades. (shrink)

In their self-understanding, expert committees solely draw on scientific knowledge to provide policy advice. However, we try to show, first, on the basis of material related to the German Radiation Protection Commission that much of their work consists in active model building. Second, expert advice is judged by criteria that diverge from standards used for judging epistemic research. In particular, the commitment to generality or universality is replaced by the criterion of specificity, and the value of precision gives way to (...) epistemic robustness. Third, non-epistemic considerations are included in the reasoning—albeit hesitantly. Manageability and social robustness, understood as compatibility with widespread value attitudes in society, affect the content of the recommendations. (shrink)

Increasingly, companies implement social and environmental standards as instruments towards corporate social responsibility (CSR) in supply chains. This is based on the assumption that such standards increase legitimacy among stakeholders. Yet, a wide variety of standards with different requirement levels exist and companies might tend to introduce the ones with low exigencies, using them as a legitimacy front. This strategy jeopardizes the reputation of social and environmental standards among stakeholders and their long-term trust in these instruments of CSR, meaning that (...) all expenses for their implementation are of no avail for the companies. Therefore, this paper highlights which criteria are important for the selection, implementation and improvement in order to achieve a company's aim, but also to strengthen the legitimacy of social and environmental standards. This research is based on conceptual thought and some existing empirical research, comparing four different social and environmental standards, revealing weaknesses and strengths. It exposes the basic conditions for the success of such standards among stakeholders and identifies the need for more empirical data. (shrink)

It is well known that the American director Terrence Malick studied philosophy under Stanley Cavell and translated the work of Martin Heidegger. He eventually traded Harvard and Oxford for Hollywood, though. This essay traces Malick's evolution from budding academic philosopher to cinematic innovator. It suggests that Malick's cinematic career should be viewed as both a rejection of academic philosophy and a celebration of the examined life.

Discussion of sexuality in African cultures has a long history, but since the 1990s ethical reflections on homosexuality on the continent have often degenerated into furors and provoked a spate of anti-gay legislation in several countries. Refutations of homophobic dispositions encounter as barrier a pervasive belief in African cultures, that childbearing for community replenishment is a cherished moral duty. Several philosophers consider these to be exaggerated inhibitions that unjustifiably impede social acceptance of homosexuality, and have proposed as a solution what (...) they consider to be self-justifying political-moral principles, that terminate in value-pluralistic ideas such as the acceptance of the equality of sexual orientations and vindication of the right to the freedom to choose and satisfy sexual desire. I question the adequacy of such self-justificatory normative principles and consider the solutions they proffer as depreciating the moral point of the African pro-natalist position. Consequently, I develop a moral argument grounded in the ontology of Kwame Gyekye’s moderate communitarian theory of personhood as the most persuasive justification for homosexuality. (shrink)

The concept of resistance in nursing has been garnering more interest in the last few years, with emerging focus on working conditions, power differentials in clinical settings, health inequities, and planetary health concerns. As a result, it's important to identify what is being resisted, and what is the purpose of the resistance carried out. In whatever way resistance is referenced in nursing, outright or not, it is our contention that it's in response to the same underlying cause, barring some local (...) and contextual variations, which we refer to as ‘the Beast’, where the real catastrophe is societal, and is ‘existential, affective and metaphysical’. It therefore seems coherent to consider this macro catastrophe from an ontological point of view, that is, from the standpoints of ‘being’ in relation to the world, which necessarily refers to specific ways of apprehending reality. In this article, we therefore present two ontologies ‐ antagonistic in every respect, to better situate resistance in nursing in a larger ecosystem. Using the Invisible Committee's book and call to actionTo our friends, this is our modest contribution to celebrate resistance, to help equip fellow nurses to better organise and strategize in the face of incessant growth and too often undesirable change in healthcare. (shrink)

In these essays, written between 1909 and 1954 and first published as a collection in 1957, the eminent philosopher relates the "I-Thou" dialogue to such varied fields as religion, social thought, philosophy, myth, drama, literature, and art. Buber thus responds to the crises and challenges of the 20th century and enables the reader to follow his lifelong struggles toward "authentic existence.".

According to the Kripke-Putnam orthodoxy, a term like 'water' refers to samples of the same substance as the items on the basis of which the term was introduced. However, observations due to Needham and Leslie cast doubt on the idea that there is a uniquely privileged notion of substance relevant to the determination of reference, in which case it would seem at best indeterminate what the word `water' refers to. In response to this problem, Gómez-Torrente has argued that there is (...) a privileged notion of substance that plays a role in the determination of reference, namely, the ordinary notion of substance. This paper argues that Gómez-Torrente's proposal is not successful. Contrary to what Gómez-Torrente supposes, there is no uniquely privileged ordinary notion of substance; rather, there are many notions of substance compatible with the meaning of 'substance' none of which seems privileged over the rest. (shrink)

We criticize speculations to the effect that quantum mechanics is fundamentally about information. We do this by pointing out how unfounded such speculations in fact are. Our analysis focuses on the dubious claims of this kind recently made by Anton Zeilinger.

This paper discusses Austin’s goldfinch example from “Other Minds,” which plays a central role in Kaplan’s Austin’s Way with Skepticism. The paper aims to clarify the obscure distinction Austin makes in connection with this example, between cases in which we know and can prove and cases in which we know but can’t prove. By discussing a couple of remarks that Austin makes in passing, a view is extracted from his text that stands in conflict with Kaplan’s reading at a fundamental (...) point. The view proposed emphasizes the role of law-like generics in our practice of knowledge attribution, and brings out the disjunctivist elements in Austin’s conception. It is argued that the response to skepticism that Kaplan ascribes to Austin is not fully satisfactory, since it fails to tell us what makes some challenges to our knowledge claims appropriate and others outrageous. The alternative view proposed in this paper can handle this problem without postulating the sort of general external criterion that Kaplan’s Austin rightly rejects. (shrink)

There is a long-standing debate in the philosophy of action and the philosophy of science over folk psychological explanations of human action: do the (perhaps implicit) generalizations that underwrite such explanations purport to state contingent, empirically established connections between beliefs, desires, and actions, or do such generalizations serve rather to define, at least in part, what it is to have a belief or desire, or perform an action? This question has proven important because of certain traditional assumptions made about the (...) role of law-statements in scientific explanations. According to this tradition, law-statements take the form of generalizations, and the laws we find in well-established sciences are contingent and empirical; as such, if the kinds of generalizations at work in folk psychological explanations of human action act like definitions, or state conceptual connections, then such generalizations could not play the kind of explanatory role we find in mature sciences. This paper argues that the aforementioned way of framing the debate reflects a still powerful but impoverished conception of the role laws play in scientific explanations, a conception that, moreover, cannot be reconciled with a good deal of actual scientific practice. When we update the philosophy of science, we find the concerns that are raised for folk psychological explanations largely evaporate or are found not to be specific to such explanations. (shrink)

Die Philosophie Karl Leonhard Reinholds (1757-1823) findet heute vermehrt Beachtung. Während dieser Denker lange Zeit als Popularisator Kants, als Vorläufer Fichtes oder als tatsachenphilosophischer Antipode Schellings und Hegels wahrgenommen wurde und gemeinhin im Ruf eines unsteten und unselbständigen Geistes stand, ist seit einigen Jahrzehnten eine Gegentendenz feststellbar: Reinholds Denkentfaltung wird zunehmend in ihrem gesamten Umfang sowie als eigenwilliger und innovativer Ansatz innerhalb der postkantischen Systemphilosophie zur Kenntnis genommen. Mehr und mehr wird anerkannt, dass Reinhold entscheidende Anstöße zur Entstehung des deutschen (...) Idealismus gegeben und diese Strömung zugleich auf der Grundlage von Einsichten, die in die Richtung der Phänomenologie und Sprachphilosophie des 20. Jahrhunderts weisen, kritisiert hat. Die in diesem Band vereinigten Beiträge gehen auf die I. Internationale Reinhold-Tagung zurück, die vom 14. bis 18. März 1998 in Bad Homburg stattgefunden hat. Sie geben systematische Fragestellungen und entwicklungsgeschichtliche Kontexte aus Reinholds kantischer Phase der Elementarphilosophie, aus der Periode seiner Zusammenarbeit mit Fichte und Jacobi sowie aus seiner sprachphilosophisch orientierten Spätzeit wieder. Alles in allem spiegeln sie das gegenwärtige Bedürfnis, Reinhold zu entdecken, sein Denken und Schaffen in seinen Wandlungen und in seiner thematischen Breite aufzuarbeiten und nachzuvollziehen. Zudem sind sie repräsentativ für die aktuell bestehenden vielfältigen Zugänge zu diesem produktiven Philosophen. (shrink)

Philosophy underwent a corresponding theatrical shift in the modern era, most importantly through the work of Kierkegaard, Nietzsche, Sartre, and Camus.

Worldwide, antibiotic use is increasing, but many infections against which antibiotics are applied are not even caused by bacteria. Over‐the‐counter and internet sales preclude physician oversight. Regional differences, between and within countries highlight many potential factors influencing antibiotic use. Taking a systems perspective that considers pharmaceutical commodity chains, we examine antibiotic overuse from the vantage point of both sides of the therapeutic relationship. We examine patterns and expectations of practitioners and patients, institutional policies and pressures, the business strategies of pharmaceutical (...) companies and distributors, and cultural drivers of variation. Solutions to improve antibiotic stewardship include practitioners taking greater responsibility for their antibiotic prescribing, increasing the role of caregivers as diagnosticians rather than medicine providers, improving their communication to patients about antibiotic treatment consequences, lessening the economic influences on prescribing, and identifying antibiotic alternatives. (shrink)

Luck egalitarians need to address the question of cost-responsibility: If an individual is responsible for being worse off than others, then what benefits, if any, is that individual uniquely cost-responsible for? By applying luck egalitarianism to justice in health I discuss different answers to this question inspired by two different interpretations of luck egalitarianism, namely ‘standard luck egalitarianism’ and ‘all luck egalitarianism’, respectively. Even though I argue that the latter is more plausible than the former, I ultimately suggest and defend (...) a third interpretation of luck egalitarianism, which I label ‘universal luck egalitarianism’. Finally, I adjust my findings to a (all things considered) more plausible currency, namely welfare. (shrink)

Berulang kali saya ditanya oleh sesama umat Katolik apakah buku bacaan Misa Katolik juga dipakai oleh gereja Protestan, sebab mereka mengalami bahwa dalam ibadat hari minggu gereja Kristen lain dipakai bacaan Alkitab yang sama. Memang belum banyak diketahui perkem-bangan luar biasa yang selama setengah abad terakhir terjadi berkaitan dengan lectionarium atau leksionari ibadat hari Minggu dalam seluruh umat Kristen. Karena itu publikasi thesis Pendeta Y.B. Mulyono (S2 di STT Proklamasi) tentang Revised Common Lectionary (RCL) sangat di-butuhkan, dan membantu juga diri (...) saya.... Thesis M. yang diterbitkan dengan rapi oleh Grafika KreasIndo (Sinode GKI) menjadi bacaan penting bagi setiap pengkhotbah, entah pendeta atau imam, dan hendaknya mendapat tempat dalam pendidikan hermeneutika dan homiletika para calon imam dan pendeta. (Martin Harun, Guru Besar Ilmu Teologi Emeritus, Sekolah Tinggi Filsafat Driyarkara, Jakarta). (shrink)

Funding policies for science are usually directed at supporting technological innovations. The im-pact and success of such policies depend crucially on how science and technology are connected to each other. I propose an “interactive view” of the relationship between basic science and technol-ogy development which comprises the following four claims: First, technological change derives from science but only in part. The local models used in accounting for technologically relevant phenomena contain theoretical and non-theoretical elements alike. Second, existing technologies and rules (...) of experience constitute another major repository of technological inventions. Third, technology dynamics is only weakly coupled to progress in basic science but it is closely related to science. There is a dependence of technological change on a more fundamental understanding, to be sure, but it is of an indirect and long-term character. Fourth, progress in basic research is some-times the effect of technological change. Technological change sometimes brings about increased theoretical understanding. (shrink)

We give a self-contained proof of the preservation theorem for proper countable support iterations known as “tools-preservation”, “Case A” or “first preservation theorem” in the literature. We do not assume that the forcings add reals.

from the fact that the subject reacts faster to those words than to words that were not on the list. The subject.

I critically examine the plausibility of Kant’s conception of rationalising, a form of self-deception that plays a crucial role for Kant’s moral psychology and his conception of the functions of critical practical philosophy. The main problem I see with Kant’s conception is that there are no theory-independent criteria to determine whether an exercise of rational capacities constitutes rationalising. Kant believes that rationalising is wide-spread and he charges the popular philosophers and other ethical theorists with rationalising. Yet, his opponents could, in (...) turn, charge him with rationalising and some theorists, namely Act-Consequentialists, seem to be in an even stronger position to charge Kant with rationalising than vice versa. In response, I propose standards that do not assume a specific normative theory and that become apparent when we look at clear-cut abuses of rationality. These standards of minimally decent reasoning can help us diagnose rationalising. I develop these standards by looking at inadequate uses of rational capacities that should strike us as problematic regardless of the specific ethical theory we adopt. I emphasise that even an abuse of rational capacities can yield true results and that we can never tell from a single judgement that someone rationalises. Rather, we must look for patterns. (shrink)

Drawing on new manuscript sources, this volume offers seven contributions on Hermann Samuel Reimarus, the most significant biblical critic in eighteenth-century Germany, as well as an eminent Enlightenment philosopher, a renowned classicist ...