Secreted signaling molecules act as morphogens to control patterning and growth in many developing tissues. Since locally produced morphogens spread to form a concentration gradient in the surrounding tissue, spreading is generally thought to be the key step in the non‐autonomous actions. Here, we review recent advances in tool development to investigate morphogen function using the role of decapentaplegic (Dpp)/bone morphogenetic protein (BMP)‐type ligand in the Drosophila wing disc as an example. By applying protein binder tools to distinguish between the (...) roles of Dpp spreading and local Dpp signaling, we found that Dpp signaling in the source cells is important for wing patterning and growth but Dpp spreading from this source cells is not as strictly required as previously thought. Given recent studies showing unexpected requirements of long‐range action of different morphogens, manipulating endogenous morphogen gradients by synthetic protein binder tools could shed more light on how morphogens act in developing tissues. (shrink)

In this paper, I study the kind of questions we can ask about the existence of numbers. In addition to asking whether numbers exist, and how, I argue that there is also a third relevant question: why numbers exist. In platonist and nominalist accounts this question may not make sense, but in the psychologist account I develop, it is as well-placed as the other two questions. In fact, there are two such why-questions: the causal why-question asks what causes numbers to (...) exist and the teleological why-question asks for what purpose numbers exist. I argue that in a psychologist constructivist account, in which numbers are understood to exist as referents of a particular type of culturally shared concepts, both why-questions can get plausible answers. (shrink)

Though ancient Pyrrhonian skepticism is apparently based on disagreement, this aspect of skepticism has been widely neglected in contemporary discussion on skepticism. The paper provides a rational reconstruction of the skeptical argument from disagreement that can be found in the books of Sextus Empiricus. It is argued that this argument forms a genuine skeptical paradox that has no fully satisfactory resolution. All attempts to resolve it make knowledge or justified belief either intuitively too easy or impossible.

Die Untersuchung von Strukturen des Exemplarischen ist in den letzten Jahren vermehrt in den Fokus geisteswissenschaftlicher Forschung gerückt. Der Band beleuchtet in systematischer und historischer Perspektive Funktionen der Verwendung von Bildern als Beispielen, Illustrationen und Exempla. Im Mittelpunkt des Buches steht die Frage, wie Bilder in epistemologische, kunsttheoretische und philosophische Diskurse eingebunden sind. Die grundlegende Annahme lautet: Der theoretische Umgang mit Bildern gehorcht einer Logik des Exemplarischen, welche die Allgemeinheit der Argumente an die konkrete Gegebenheit eines Anschaulichen bindet. 'Logik' wird (...) dabei in einem weiten, inklusiven Sinn verstanden, der die lange Tradition der Rhetorik, aber auch Kants Überlegungen zum reflexiven ästhetischen Urteil und die psychoanalytische Analyse des singulären Falls umfasst. (shrink)

Resenha do livro "Morte", de Giovanni Casertano.

How is knowledge of geometry developed and acquired? This central question in the philosophy of mathematics has received very different answers. Spelke and colleagues argue for a “core cognitivist”, nativist, view according to which geometric cognition is in an important way shaped by genetically determined abilities for shape recognition and orientation. Against the nativist position, Ferreirós and García-Pérez have argued for a “culturalist” account that takes geometric cognition to be fundamentally a culturally developed phenomenon. In this paper, I argue that (...) when understood as moderate versions supported by the state-of-the-art research, the nativist and culturalist views are in fact possible to reconcile. While Ferreirós and García-Pérez present the work of Spelke and colleagues as implying that geometric cognition is genetically determined, I argue that they fail to appreciate the role that Spelke and colleagues see for cultural factors. On this basis, I provide theoretical and terminological clarifications and show that moderate versions of the nativist and culturalist view are in fact consistent with each other. I then propose a unifying theoretical framework for future study that can integrate the two accounts in ontogeny by moving beyond the crude nature (nativism) vs. nurture (culturalism) dichotomy. (shrink)

How do we acquire the notions of cardinality and cardinal number? In the (neo-)Fregean approach, they are derived from the notion of equinumerosity. According to some alternative approaches, defended and developed by Husserl and Parsons among others, the order of explanation is reversed: equinumerosity is explained in terms of cardinality, which, in turn, is explained in terms of our ordinary practices of counting. In their paper, ‘Cardinality, Counting, and Equinumerosity’, Richard Kimberly Heck proposes that instead of equinumerosity or counting, cardinality (...) is derived from a cognitively earlier notion of _just as many_. In this paper, we assess Heck’s proposal in terms of contemporary theories of number concept acquisition. Focusing on bootstrapping theories, we argue that there is no evidence that the notion of _just as many_ is cognitively primary. Furthermore, since the acquisition of cardinality is an enculturated process, the cognitive primariness of these notions, possibly including _just as many_, depends on various external cultural factors. Therefore, being possibly a cultural construction, _just as many_ could be one among several notions used in the acquisition of cardinality and cardinal number concepts. This paper thus challenges those accounts which seek for a fundamental concept underlying all aspects of numerical cognition. (shrink)

We present an argument against physicalism in two steps: 1) Physics reduces the world to a mathematical structure; 2) The notion of 'structure' only makes sense when carried by something and interpreted by something else. Physicalism does not allow such a carrier and interpreter at a fundamental level, hence it must be wrong. An extended notion of Mind is presented as the fundamental 'hardware' which is necessary by the argument. In particular, qualia correspond to the 'monitor component' of mind. Some (...) ideas are presented on how to extend this mind-matter relation to a more elaborate picture: (1) A system of two complementary reductionisms (one physical, the other mental) may hint toward a deeper reality in which mind and the physical world are closely entangled. (2) A division of mind into a conscious 'monitor' and an unconscious 'processor' is suggested using the analogy of dreams. Finally, the problem of Solipsism and the existence of 'minds other than my own' is discussed. (shrink)

This paper addresses the questions concerningthe relationship between scientific andcognitive processes. The fact that both,science and cognition, aim at acquiring somekind of knowledge or representationabout the world is the key for establishing alink between these two domains. It turns outthat the constructivist frameworkrepresents an adequate epistemologicalfoundation for this undertaking, as its focusof interest is on the (constructive)relationship between the world and itsrepresentation. More specifically, it will beshown how cognitive processes and their primaryconcern to construct a representation of theenvironment and to (...) generate functionallyfitting behavior can act as the basis forembedding the activities and dynamics of theprocess of science in them by making use ofconstructivist concepts, such as functionalfitness, structure determinedness, etc.Cognitive science and artificiallife provide the conceptual framework of representational spaces and their interactionbetween each other and with the environmentenabling us to establish this link betweencognitive processes and thedevelopment/dynamics of scientific theories.The concepts of activation, synaptic weight,and genetic (representational) spaces arepowerful tools which can be used asexplanatory vehiclesfor a cognitivefoundation of science, more specifically forthe context of discovery (i.e., thedevelopment, construction, and dynamics ofscientific theories and paradigms).Representational spaces do not only offer us abetter understanding of embedding science incognition, but also show, how theconstructivist framework, both, can act as anadequate epistemological foundation for theseprocesses and can be instantiated by theserepresentational concepts from cognitivescience. The final part of this paper addresses somemore fundamental questions concerning thepositivistic and constructivist understandingof science and human cognition. Among otherthings it is asked, whether a purelyfunctionalist and quantitative view of theworld aiming almost exclusively at itsprediction and control is really satisfying forour intellect (having the goal of achieving aprofound understanding of reality). (shrink)

This interview deals with the major themes in the work of Ruth Millikan. Her most fundamental idea is that the intentionality of inner and outer representations can be understood in analogy to biological functions. Another innovative feature is the view that thought and language stand parallel to each other. Thirdly, the basic ideas concerning the ontology and the epistemology of concepts are explained. Millikan aims at clarifying her position by contrasting it with Dretske, Fodor, Sellars, and Brandom. Finally, the interview (...) addresses topics that pose problems for her account as well as questions she does not treat in her work. (shrink)

It is the nature of powerful ideas that they can summarize a ground-breaking concept in a plain and simple message. In this sense, the concept of sustainability is a very powerful idea. However, although the sustainability debate has already brought about considerable conceptual progress, a pivotal dimension to sustainable development has so far been widely neglected. This article argues that in addition to the ecological, economic, and social dimension, sustainability critically depends on the moral dimension of institutional legitimacy. Against the (...) backdrop of globalization, conventional models of creating and legitimizing institutions are increasingly challenged. Therefore, it is also business that is to play an ever more important role in contributing to fair and functioning institutions. The article discusses “corporate citizenship” as an economic concept as a useful starting point for this new understanding of the business of business. In effect, the underlying objective of this paper is to present a theoretical link between the concepts of sustainability and corporate citizenship. The central thesis is that private enterprises who cooperatively take responsibility for their institutional environment strengthen the moral dimension of institutional legitimacy: They actively contribute to empowering sustainability by corporate citizenship. (shrink)

Fogelin’s neo-Pyrrhonism is skepticism about epistemology and philosophy more generally. Philosophical reflection on ordinary epistemic practices leads us to deny the possibility of knowledge and justified belief. However, instead of accepting the dogma that knowledge and justified beliefs are impossible, a neo-Pyrrhonist rejects the philosophical premises that lead to this conclusion. Fogelin argues in particular that contemporary theories of justification cannot avoid dogmatic skepticism, because they are committed to the premises of the skeptical argument deriving from the modes of Agrippa. (...) It is argued against Fogelin that those theories can and typically do deny one or another of the premises and thus can avoid the skeptical conclusion. Neo-Pyrrhonism should rather be defended by arguing that the premises of the Agrippan argument are intuitively plausible and that neo-Pyrrhonism provides the best resolution of the resulting paradox. Only neo-Pyrrhonism both explains the intuitive plausibility of the premises and avoids dogmatic skepticism. (shrink)

This paper investigates whether AI can possess wisdom, a complex and deeply human capacity. We adopt an interdisciplinary approach, drawing on philosophy, 4E cognition, Material Engagement Theory, and engaged epistemology, to argue that wisdom is a dynamic force unfolding through meaningful life experiences and resonant interactions with the world. Central to our discussion is Rosa's concept of resonance, essential for fostering personal growth, emotional empathy, as well as existential and bodily connectedness to the world and its unfolding into an uncertain (...) future. Despite the advanced capabilities of AI/Large Language Models (LLMs), we demonstrate their inability to embody wisdom due to their lack of deep sense-making, embodied interaction, and meaningful engagement with the world and future potentials. We emphasize the need for cultivating human wisdom to ensure technological advancements enrich rather than diminish the human experience, advocating for a balanced and reflective human-technology relationship. (shrink)

Das Buch weist in exemplarischen Fallstudien von der Antike bis zur Gegenwart die zentrale Rolle von Bildern für Prozesse der Vergemeinschaftung auf. Gegen Ende des 20. Jahrhunderts setzt in der akademischen Diskussion eine verstärkte Rückwendung zum Konzept der Gemeinschaft ein.

This work was awarded the John Templeton Award for Theological Promise 2009.

Die neue deutsche Kierkegaard-Übersetzung beruht auf der dänischen Edition Søren Kierkegaards Skrifter, der vollständigen, historisch-kritischen Ausgabe von Kierkegaards Schriften, die seit 1994 im Søren Kierkegaard Forschungszentrum in Kopenhagen erstellt wird. Journale und Aufzeichnungen Die DSKE beginnt mit der Übersetzung der auf elf Bände angelegten Journale und Aufzeichnungen. Hier hat die dänische Ausgabe insofern neue Maßstäbe in der Editionsphilologie gesetzt, als sie frühere Eingriffe in die Manuskripte durch Verwendung von Licht- und Elektronenmikroskopie von Kierkegaards eigenem Text unterscheidet. Dadurch lassen sich auch (...) von Kierkegaard selbst unleserlich gemachte Eintragungen entziffern. Editionsberichte geben Auskunft über Überlieferungsverhältnisse, Chronologie und Inhalt der Bände. Daneben bietet die DSKE eine Fülle von Realkommentaren, die zusammen mit zahlreichen Abbildungen ein neues und tieferes Verständnis von Kierkegaards Gesamtwerk ermöglichen. Eine Besonderheit ist die diplomatische Wiedergabe des Textes: Kierkegaards Gewohnheit, zunächst die Innenseite des Papiers zu beschriften und spätere Bemerkungen am Rand hinzuzufügen, wird - wie in der dänischen Edition - im Druckbild wiedergegeben. So ist erkennbar, dass es sich bei den Texten um gewachsene Einheiten handelt. (shrink)

One key question in the philosophy of artificial intelligence (AI) concerns how we can recognize artificial systems as intelligent. To make the general question more manageable, I focus on a particular type of AI, namely one that can prove mathematical theorems. The current generation of automated theorem provers are not understood to possess intelligence, but in my thought experiment an AI provides humanly interesting proofs of theorems and communicates them in human-like manner as scientific papers. I then ask what the (...) criteria could be for recognizing such an AI as intelligent. I propose an approach in which the relevant criteria are based on the AI’s interaction within the mathematical community. Finally, I ask whether we can deny the intelligence of the AI in such a scenario based on reasons other than its (non-biological) material construction. (shrink)

Ausgehend von historischen und sozialtheoretischen Befunden rekonstruieren wir zunächst in skizzenhafter Form, wie es zu einer Konstruktion von Behinderungen als Verkörperungen einer Mangelhaftigkeit anthropologischen Ausmaßes gekommen ist. In Anschluss hieran vertreten wir die These, dass Behinderung eine kulturelle Norm darstellt, die der Kultur selbst Grenzen setzt. Nicht der Mensch stellt das „eigentliche“ Mängelwesen dar, sondern die gesellschaftliche Kultur vorenthaltener oder eingeschränkter Teilhabe sowie die pädagogische Kultur mangelhafter Bildungsmaßnahmen. In ethischer Hinsicht begründen wir diese These von der Verantwortung gegenüber dem Anderen (...) her, dessen Andersheit wir als irreduzibel bzw. radikal fassen. Wir schließen mit einer kurzen Reflexion über die Frage, wie sich dieser veränderte Zugang zu Menschen mit Behinderungen bildungstheoretisch fassen lässt. (shrink)

Studies involving direct language imitation tasks have shown that pronunciation ability is related to musical competence and working memory capacities. However, this type of task may measure individual differences in many different linguistic dimensions, other than just phonetic ones. The present study uses an indirect imitation task by asking participants to a fake a foreign accent in order to specifically target individual differences in phonetic abilities. Its aim is to investigate whether musical expertise and working memory capacities relate to phonological (...) awareness (i.e., participants’ implicit knowledge about the phonological system of the target language and its structural properties at the segmental, suprasegmental and phonotactic levels) as measured on this task. To this end, French native listeners (N = 36) graded how well German native imitators (N = 25) faked a French accent while speaking in German. The imitators also performed a musicality test, a self-assessment of their singing abilities and working memory tasks. The results indicate that the ability to fake a French accent correlates with singing ability and musical perceptual abilities, but not with working memory capacities. This suggests that heightened musical abilities may lead to an increased phonological awareness probably by providing participants with highly efficient memorization strategies and highly accurate long-term phonetic representations of foreign sounds. Comparison with data of previous studies shows that working memory could be implicated in the pronunciation learning process which direct imitation tasks target, whereas musical expertise influences both storing of knowledge and later retrieval here assessed via an indirect imitation task. (shrink)