This handsome book captures in words and pictures the powerful emotions that have circled around Chicagos popular mayor, Harold Washington, and gives readers a glimpse of a man who has won over an entire city.

Marc Hauser puts forth the theory that humans have evolved a universal moral instinct, unconsciously propelling us to deliver judgments of right and wrong independent of gender, education, and religion. Combining his cutting-edge research with the latest findings in cognitive psychology, linguistics, neuroscience, evolutionary biology, economics, and anthropology, Hauser explores the startling implications of his provocative theory vis-à-vis contemporary bioethics, religion, the law, and our everyday lives.

Cet article propose un nouvel examen de l'image d'Alexis Ier Comnène dans l'Historia Ierosolimitana d'Albert d'Aix, afin d'en apprécier les nuances et les subtilités. Bien qu'Albert d'Aix soit reconnu pour son impression généralement positive d'Alexis Ier, une relecture attentive de son œuvre démontre plutôt une image ambivalente de l'empereur et des Byzantins. En scrutant les motifs d'Albert d'Aix, il est possible de constater une disposition favorable du chroniqueur lorsqu'il s'agit de souligner les relations privilégiées entre Alexis Ier et les souverains (...) lotharingiens de Jérusalem. En contrepartie, lorsque les Byzantins ne répondent plus à ce besoin, l'opinion de l'auteur se veut généralement moins clémente en reflétant davantage les accusations dirigées contre les Grecs au début du XIIe siècle. Un examen du vocabulaire employé par Albert d'Aix révèle également une évolution des impressions du chroniqueur à travers les différentes phases d'écriture de son récit et témoigne de l'évolution des desseins politiques de l'auteur dans le temps. Bien que l'Historia Ierosolimitana se distingue à bien des égards de la tradition des Gesta Francorum et des autres récits de la première croisade, l'étude conclut que les intentions de son auteur n'étaient pas moins tendancieuses. (shrink)

What altered states of consciousness—the dissolution of feelings of time and self—can tell us about the mystery of consciousness. During extraordinary moments of consciousness—shock, meditative states and sudden mystical revelations, out-of-body experiences, or drug intoxication—our senses of time and self are altered; we may even feel time and self dissolving. These experiences have long been ignored by mainstream science, or considered crazy fantasies. Recent research, however, has located the neural underpinnings of these altered states of mind. In this book, neuropsychologist (...) Marc Wittmann shows how experiences that disturb or widen our everyday understanding of the self can help solve the mystery of consciousness. Wittmann explains that the relationship between consciousness of time and consciousness of self is close; in extreme circumstances, the experiences of space and self intensify and weaken together. He considers the emergence of the self in waking life and dreams; how our sense of time is distorted by extreme situations ranging from terror to mystical enlightenment; the experience of the moment; and the loss of time and self in such disorders as depression, schizophrenia, and epilepsy. Dostoyevsky reported godly bliss during epileptic seizures; neurologists are now investigating the phenomenon of the epileptic aura. Wittmann describes new studies of psychedelics that show how the brain builds consciousness of self and time, and discusses pilot programs that use hallucinogens to treat severe depression, anxiety, and addiction. If we want to understand our consciousness, our subjectivity, Wittmann argues, we must not be afraid to break new ground. Studying altered states of consciousness leads us directly to the heart of the matter: time and self, the foundations of consciousness. (shrink)

Dans la pensée philosophique d'Emmanuel Levinas, le mot « Dieu » n'est pas inaudible. Il peut venir à l'idée. Il peut tomber sous le sens – en deçà de tout sens thématisé, à revers des prétentions souveraines de la conscience. À la condition toutefois que parvienne à être décrite l'intrigue anarchique que ce mot noue dans l'idée de l'Infini, dans le Visage, dans la Kénose du sujet, dans le Dire du verset ou l'Emphase de la métaphore.Les articles recueillis dans cet (...) ouvrage tentent, sous ces divers aspects, de décrire l'inouïe Transcendance de ce mot « Dieu » désormais arraché à toute archê – à tout fondement onto-théo-logique. Ils se hasardent aussi à suggérer les résonnances théologiques et bibliques de cet « autrement dire Dieu » préservant l'anarchie du Transcendant. C'est par le Haut que se noue tout vrai dialogue entre le philosophique et le théologique. (shrink)

The Food and Drug Administration authorizes the marketing of a drug only for uses that the manufacturer has demonstrated to be safe and effective, based on evidence from at least two clinical trials. However, the FDA does not regulate the practice of medicine, so physicians may prescribe drugs in any manner they choose. Prescribing drugs in ways that deviate from the uses specified in the FDA-approved drug label, package insert, and marketing authorization is referred to as off-label prescribing. This occurs (...) when physicians prescribe a drug for a therapeutic purpose other than the one approved by the FDA; treat patients in a different age cohort or gender than the population on which it was tested; or prescribe a different dose, for a different duration of use, or a different mode of administration than indicated on the label. (shrink)

This article argues that the misalignment of private profit-maximizing objectives with public health needs causes institutional corruption in the pharmaceutical sector and systematically leads firms to act contrary to public heath. The article analyzes how financial incentives generate a business model promoting harmful practices and explores several means of realigning financial incentives in order to foster therapeutic innovation and promote the rational use of medicines.

texte aujourd’hui fameux, repose sur un document connu également de la Vie latine d’Adam et Ève et que l’auteur qoumrânien a remanié. nowadays a famous text, depends on a document which is also known from the Latin Life of Adam and Eve, and which has been reworked by the author from Qumran.

This work studies early modern thought concerning the ontology of ideas. I endeavor to establish, contrary to some current scholarship, that the Early Moderns remained firmly in the grip of a substance/mode ontology narrowed from the substance/property distinction inherited from Aristotle. I argue that this traditional dichotomy provides the most philosophically and historically fruitful approach to understanding early modern thought. In particular, I demonstrate how the increasing radicalization in the metaphysics of the moderns is best explained by remaining within the (...) substance/mode ontology. Competing contemporary approaches, especially ones that attempt to employ concepts such as reification and object talk in place of the traditional ontology, do not sufficiently penetrate to the core issues facing the Moderns. Rather than seeking to abandon the categories of substance and mode, the Moderns sought, perhaps vainly, to find room for ideas within it. I proceed by providing background from Aristotle and the Medievals, go on to discuss the philosophical views of Descartes, Malebranche, Arnauld, Locke and Berkeley. The development of idea philosophy culminates in Berkeley, who creates a hybrid ontic category I call 'quasi-substance.' Ideas for Berkeley are ontically dependent on minds , but external to them in the sense that the relationship between ideas and minds are two-place . I demonstrate how this understanding explains the radical metaphysical positions he takes, especially his commitment to perceptual heterogeneity. I conclude that rather than abandoning the traditional ontic categories, the Moderns adhered to them desperately, and thus are best understood through them. (shrink)

Recent experiments in normal subjects using neuroimaging demonstrate that the dorsal cortico-cortical pathway is involved during purely perceptual activities. Pathological cases with right posterior parietal lesions show deficits in visuospatial perception. It is argued that the radical dichotomy between perception and action pathways, as heralded in Milner and Goodale's book should be reexamined. The idea of distributed networks using resources in both visual pathways and recruited as a function of task demands is presented.

Models of cognitive vulnerability claim that depressive symptoms arise as a result of an interaction between negative affect and cognitive reactions, in the form of dysfunctional attitudes and negative inferential style. We present a model that complements this approach by focusing on the appraisal processes that elicit and differentiate everyday episodes of emotional experience, arguing that individual differences in appraisal patterns can foster negative emotional experiences related to depression (e.g., sadness and despair). In particular, dispositional appraisal biases facilitating the elicitation (...) of these emotions more frequently and more intensely. This, in turn, is likely to have a negative influence on cognitive processing and emotion regulation in general. (shrink)

Television series explicitly pursue an entertainment goal rather than a learning one; nevertheless, they convey information about care. French and American series depicting doctors and care workers have reached record-breaking audiences. Spectators try to understand care as an activity through dramatic situations. They are all the more curious and liable to consider the activity of the nurses as a vicariant model that they wish to become a doctor or a care worker. Which behaviors get the spectators’ attention? Which reasoning do (...) they deduce from them? Does the paramedical training then modify the representations they form about care and the nursing profession while watching television series? (shrink)

Nous appelons «thèse des descriptions multiples» l'opinion qui veut qu'une seule et même action peut etre decrite de plusieurs façons différentes selon que Ton prend en considération ou non les différentes conséquences, plus ou moins lointaines, de cette action. Cette thèse joue chez certains penseurs un rôle essentiel dans la solution du problème de l'individuation des actions. Chez D. Davidson notamment, elle intervient de façon décisive dans la démonstration de sa fameuse thèse que toute action se réduit à des mouvements (...) corporels. Nous entendons montrer, premièrement, que la thèse des descriptions multiples, à supposer même qu'elle soit vraie, ne saurait remplir le rôle que lui assigne Davidson dans le contexte de l'individuation des actions; deuxièmement, que cette thèse est fondée en fait sur l'ignorance de certaines distinctions importantes concernant l'action et le langage de l'action. (shrink)

English summary: The idea of a negative dialectics encapsulates the critical theory of Theodor W. Adorno in its entirety. In a critical engagement with Hegel's philosophy, Adorno develops a dialectic that is no longer tied to the idealistic concept of a speculative identity of subject and object, yet nevertheless aims at a concept of the absolute. So far neither the scope nor the argumentative consistency of this model of dialectics has been taken into account. Marc Nicolas Sommer reconstructs negative (...) dialectics through its engagement with Hegelian dialectics and defends its central claim: that negative dialectics liberates dialectics from its idealistic shackles and in doing so develops a viable concept of the absolute after Auschwitz. German description: Die kritische Theorie Theodor W. Adornos findet ihre vollstandige Artikulation im Konzept einer negativen Dialektik. In kritischer Auseinandersetzung mit der hegelschen Philosophie entwickelt Adorno die Idee einer Dialektik, die nicht mehr an das idealistische Konzept einer spekulativen Identitat von Subjekt und Objekt gebunden ist, deren gedankliche Bewegung dennoch auf einen Begriff des Absoluten ausgerichtet ist. Konzeptueller Anspruch, begrifflicher Umfang und argumentative Konsistenz dieses zweiten grossen Modells dialektischen Denkens sind bis heute nicht geklart.Marc Nicolas Sommer rekonstruiert negative Dialektik aus der Auseinandersetzung mit Hegel und verteidigt ihren Anspruch, den eigentlichen Gehalt der hegelschen Dialektik von seinen idealistischen Schlacken befreit zu haben und aus dieser Denkbewegung einen nach Auschwitz tragfahigen Begriff des Absoluten zu entwickeln. (shrink)