Hope for persons with disabilities is most often associated with the possibility of cure. When cure is not achievable, there remains a dire lack in our socio-cultural imagination around and construction of hopeful disabled futurity. This paper explores Karl Rahner’s eschatology as a means of both deconstructing narrow visions of curative hope and affirming the presence of theological hope that already exists in the lives of disabled people. Ultimately, this paper argues that “crip time”—the time embodied by persons with disabilities—witnesses (...) to a prophetic relationship with time in its openness to the life-giving possibilities of the absolute future. (shrink)

Organoids are quickly becoming an accepted model for understanding human biology and disease. Pluripotent stem cells (PSC) provide a starting point for many organs and enable modeling of the embryonic development and maturation of such organs. The foundation of PSC‐derived organoids can be found in elegant developmental studies demonstrating the remarkable ability of immature cells to undergo histogenesis even when taken out of the embryo context. PSC‐organoids are an evolution of earlier methods such as embryoid bodies, taken to a new (...) level with finer control and in some cases going beyond tissue histogenesis to organ‐like morphogenesis. But many of the discoveries that led to organoids were not necessarily planned, but rather the result of inquisitive minds with freedom to explore. Protecting such curiosity‐led research through flexible funding will be important going forward if we are to see further ground‐breaking discoveries. (shrink)

The Evolving Social Responsibilities of Internet Corporate Actors: Pointers Past and Present Content Type Journal Article Category Commentary Pages 455-461 DOI 10.1007/s13347-011-0049-0 Authors Robert Madelin, Directorate General Information Society and Media, European Commission, BU25 06/183, 1049 Brussels, Belgium Journal Philosophy & Technology Online ISSN 2210-5441 Print ISSN 2210-5433 Journal Volume Volume 24 Journal Issue Volume 24, Number 4.

The rash of high-profile accounting frauds involving internal corporate accountants calls into question the individual accountant’s perceptions of the ethical climate within their organization and the limits to which these professionals will tolerate unethical behavior and/or accept it as the norm. This study uses social cognitive theory to examine the antecedents of individual corporate accountant’s perceived personal fit with their organization’s ethical climate and empirically tests how these factors impact organizational attitudes. A survey was completed by 203 corporate accountants to (...) assess their perception of relevant variables. The results of the structural equation model indicate three significant antecedents relating to ethical climate fit: higher internal levels of locus of control; greater numbers of prior job changes; and higher perceptions of an increasingly better fit with the firm’s ethical climate. Our results also indicate that higher levels of perceived fit to the ethical climate of a firm are associated with higher levels of perceived job satisfaction and organizational commitment. We also theorize that perceptions of an organization’s ethical climate may be reflections of client narcissism and serve a potential indicator of fraud risk. This is an important topic of study, since current auditing standards call for auditors to examine organizational attitudes toward fraud, but offer minimal guidance in doing so. (shrink)

In developing artificial intelligence (AI), researchers often benchmark against human performance as a measure of progress. Is this kind of comparison possible for moral cognition? Given that human moral judgment often hinges on intangible properties like “intention” which may have no natural analog in artificial agents, it may prove difficult to design a “like‐for‐like” comparison between the moral behavior of artificial and human agents. What would a measure of moral behavior for both humans and AI look like? We unravel the (...) complexity of this question by discussing examples within reinforcement learning and generative AI, and we examine how the puzzle of evaluating artificial agents' moral cognition remains open for further investigation within cognitive science. (shrink)

In this commentary on a previous Ethics and Social Welfare publication, the authors argue that inclusive and expansive dialogue about interprofessional ethics is more a matter of ??revitalizing?? traditional professional ethics than developing a new field. The dialogue will be most productive of care improvements if it incorporates the service user, includes both health and social care professions, and occurs across countries.

Crisis standards of care are a significant change in the standard level of medical care that can be given compared to normal healthcare operations. CSC are implemented when a healthcare facility is overrun due to catastrophic events like earthquakes, or in the case of SARS-CoV-2, a global pandemic. Especially in disasters, resources like hospital beds, pharmaceuticals, and staff become stretched thin, and facilities must adapt their allocation strategies for distributing scarce resources. Inevitably, a question arises: How do we allocate scarce (...) resources justly? During the coronavirus pandemic, bioethicists, healthcare practitioners, and policymakers have asked this question. A recurring worry among them... (shrink)

The Chief Eunuch of the Ottoman Harem: From African Slave to Power-Broker. By Jane Hathaway. New York: Cambridge University Press, 2018. Pp. xvi + 323. $105, £75.

Leplin attempts to reinstate the common sense idea that theoretical knowledge is achievable, indeed that its achievement is part of the means to progress in empirical knowledge. He sketches the genesis of the skeptical position, then introduces his argument for Minimalist Scientific Realism -- the requirement that novel predicitons be explained, and the claim that only realism about scientific theories can explain the importance of novel prediction.

This book proposes an original theory of epistemic justification that offers a new way to relate justification to the epistemic goal of truth-conducive belief.

Certain truths, such as genetic identity, relationships and medical history are important goods for autonomy. Knowledge about genetic heritage allows children to form a factual narrative identity. Deceit about one's genetic identity can obliterate trust and confidence. This paper seeks to analyse some of the moral issues associated with misattributed paternity.

Research by neuroscientists suggests there is a distinction in the BSTc area of the brain between males and females. In transsexual females, those considered male at birth, but who had a strong conviction that they were female, the BSTc region appears to be similar in size to the female BSTc and transsexuals considered female at birth, but who were certain they were male, had a BSTc similar to the male BSTc. This distinction leads to the conclusion that in addition to (...) the recognised markers for gender - genitalia, gonads and chromosomes - we may need to also include the BSTc, given that this current research seems to substantiate what transsexuals are saying about their gender. This paper sets out to challenge our current reliance on the standard gender indicators alone and seeks to address some issues faced by transsexuals. (shrink)

When is an ideal of a ring radical or prime? By examining its generators, one may in many cases definably and uniformly test the ideal’s properties. We seek to establish such definable formulas in rings of p-adic power series, such as $\mathbb Q_{p}\langle X\rangle $, $\mathbb Z_{p}\langle X\rangle $, and related rings of power series over more general valuation rings and their fraction fields. We obtain a definable, uniform test for radicality, and, in the one-dimensional case, for primality. This builds (...) upon the techniques stemming from the proof of the quantifier elimination results for the analytic theory of the p-adic integers by Denef and van den Dries, and the linear algebra methods of Hermann and Seidenberg.prepared by Madeline G. Barnicle.E-mail: [email protected]: https://escholarship.org/uc/item/6t02q9s4. (shrink)

We examine and reject the claim that the past-directed aspect of mental time travel (episodic memory) is unique to humans. Recent work in our laboratory with rats has demonstrated behaviours that resemble judgements about past occasions. Similar to human episodic memory, we can also demonstrate a dissociation in the neural basis of recollection and familiarity in nonhumans.

A conception of the idiotic mind was used to substantiate late 19th-century theories of mental evolution. A new school of animal/comparative psychologists attempted from the 1870s to demonstrate that evolution was a mental as well as a physical process. This intellectual enterprise necessitated the closure, or narrowing, of the ‘consciousness gap’ between human and animal species. A concept of a quasi-non-conscious human mind, set against conscious intention and ability in higher animals, provided an explanatory framework for the human–animal continuum and (...) the evolution of consciousness. The article addresses a significant lacuna in the historiographies of intellectual disability, animal science, and evolutionary psychology, where the application of a conception of human idiocy to advance theories of consciousness evolution has not hitherto been explored. These ideas retain contemporary resonance in ethology and cognitive psychology, and in the theory of ‘speciesism’, outlined by Peter Singer in Animal Liberation (1975), which claims that equal consideration of interests is not arbitrarily restricted to members of the human species, and advocates euthanasia of intellectually disabled human infants. Speciesism remains at the core of animal rights activism today. The article also explores the influence of the idea of the semi-evolved idiot mind in late-Victorian anthropology and neuroscience. These ideas operated in a separate intellectual sphere to eugenic thought. They were (and remain) deeply influential, and were at the heart of the idea of the moral idiot or imbecile, targeted in the 1913 Mental Deficiency Act, as well as in 20th-century animal and human consciousness theory. (shrink)

This article traces the multiple and rapid changes that have occurred during the past fifteen years, in theorizing "sex/gender arrangements". A secondary aspect is the reception, application and above all modification of these theories by some scholars of European medieval cultural production, in which varieties of difference are found that do not apply in modern societies. Deconstruction of the binary m/f (whether thought of as sexual or gender difference) erupted among feminist thinkers in the 1990s and eventually "queered" academic discourses (...) by destabilizing labels that had been naturalized, including a consistent gender identity for the individual in medieval or modern society. The author claims that queer and post-colonial theory, far from being antithetical to feminist theory, are out-growths of it, and exist in parallel; the proponents of each are concerned with the societal forces, including our own discourses, that maintain difference, and create communities of oppression Yet it is also necessary to raise the question, when will the next radical departure occur, and how will new theories be generated? (shrink)

As a young man growing up near Basel, Jung was fascinated and disturbed by tales of Nietzsche's brilliance, eccentricity, and eventual decline into permanent psychosis. These volumes, the transcript of a previously unpublished private seminar, reveal the fruits of his initial curiosity: Nietzsche's works, which he read as a student at the University of Basel, had moved him profoundly and had a lifelong influence on his thought. During the sessions the mature Jung spoke informally to members of his inner circle (...) about a thinker whose works had not only overwhelmed him with the depth of their understanding of human nature but also provided the philosophical sources of many of his own psychological and metapsychological ideas. Above all, he demonstrated how the remarkable book Thus Spake Zarathustra illustrates both Nietzsche's genius and his neurotic and prepsychotic tendencies.Since there was at that time no thought of the seminar notes being published, Jung felt free to joke, to lash out at people and events that irritated or angered him, and to comment unreservedly on political, economic, and other public concerns of the time. This seminar and others, including the one recorded in Dream Analysis, were given in English in Zurich during the 1920s and 1930s. (shrink)

This essay focuses on the drafts and discussions which went into the first edition of the Perambulation. Lambarde’s autograph drafts and letters set his work in dialogue with other contemporary efforts to study the English past, in particular Matthew parker’s De antiquitate Britannicae ecclesiae. This book developed in tandem with Lambarde’s. Lambarde and parker created and shared drafts in manuscript and print as they delved into Kentish church history. Remnants of their conversations about sources like the Textus Roffensis can be (...) found in their books and even in the manuscripts under discussion. Revision, like reading, was a particular social enterprise with its own conventions. The line between a finished, printed presentation copy and a manuscript draft was completely blurred: both constituted a ‘beare whelpe that lacketh licking’. (shrink)