Bone morphogenetic proteins (BMPs) are typically members of the transforming growth factor β (TGF-β) family with diverse roles in embryonic development. At least five genes with homology to BMPs are expressed during Xenopus development, along with their receptors and intracellular signalling pathways. The evidence suggests that BMPs have roles to play in both mesoderm induction and dorsoventral patterning. Studies in Xenopus have also identified a number of inhibitory binding proteins for the classical BMPs, encoded by genes such as chordin and (...) noggin. These proteins appear to be responsible for establishing a morphogen gradient of BMP4 activity, which specifies different dorsoventral fates in early gastrulae. An emerging theme is that inhibition of BMP signalling is an important mechanism regulating cell fate decisions in early development. BioEssays 21:751–760, 1999. © 1999 John Wiley & Sons, Inc. (shrink)

Within the passion narrative Matthew adds important pericopes to the Marcan text concerning both Pilate and Judas. These additional pericopes provide a rich resource for exploring the psychological motivation of and the psychological consequences for these two key actors in the betrayal and crucifixion of Jesus. The present study employs the Jungian framework of the sensing, intuition, feeling and thinking (SIFT) approach to Biblical hermeneutics to explore the interpretation of Matthew 27:19–25 (concerning Pilate) through the lenses of sensing and intuition, (...) and the interpretation of Matthew 27:3–10 (concerning Judas) through the lenses of thinking and feeling among 24 experienced preachers in Ontario, Canada. The findings confirm the hypotheses advanced by the SIFT approach that significant differences emerge between the psychological perceptions of sensing types and intuitive types, and that significant differences emerge between the psychological evaluations of thinking types and feeling types. (shrink)

A persistent paradox apparently infects disability civil rights claims. On the one hand, these rights claims are often understood to apply only to those who are sufficiently impaired in body or in mind to qualify for them because of the disadvantage they endure. On the other hand, asserting significant impairments threatens to undermine the plausibility of these claims as civil rights rather than as welfare for those who are dependent and in need of extra help. Behind this paradox lies a (...) type of categorical understanding of disability civil rights: that disability civil rights are only for those who fall into a category of disability and that this category should be defined in a particular way, in terms of disadvantaging disablement. In this article, I dispel this paradox by deploying a critical analysis of Elizabeth Barnes’s account of physical disability in her recent book, The Minority Body. In her book, Barnes makes the important critical point that disability is not “bad” difference. Instead, she argues that physical disability is a physical condition that the disability rights community is working to promote justice for. I argue that this account fails as a project of ameliorative social metaphysics because it fails to understand the role of impairment in the construction of disability antidiscrimination law. I also argue that her account risks privileging physical disability and is thus problematic as a starting place for examining disability justice. (shrink)

A textbook for third year undergraduates and postgraduates. In a challenging philosophic investigation of the origin of consciousness and human culture, Dewart (religion, emeritus, U. of Toronto) proposes a theory to explain the origin of all specifically human traits. Complementing the theory of evolution through natural selection, it explains the emergence and those the continuing evolution of characterstics through the interaction of experience and speech. Annotation copyrighted by Book News, Inc., Portland, OR.

We explored the influence of negation on cognitive dynamics, measured using mouse‐movement trajectories, to test the classic notion that negation acts as an operator on linguistic processing. In three experiments, participants verified the truth or falsity of simple statements, and we tracked the computer‐mouse trajectories of their responses. Sentences expressing these facts sometimes contained a negation. Such negated statements could be true (e.g., “elephants are not small”) or false (e.g., “elephants are not large”). In the first experiment, as predicted by (...) the classic notion of negation, we found that negation caused more discreteness in the mouse trajectory of a response. The second experiment induced a simple context for these statements, yet negation still increased discreteness in trajectories. A third experiment enhanced the pragmatic context of sentences, and the discreteness was substantially diminished, with one primary measure no longer significantly showing increased discreteness at all. Traditional linguistic theories predict rapid shifts in cognitive dynamics occur due to the nature of negation: It is an operator that reverses the truth or falsity of an interpretation. We argue that these results support both propositional and contextual accounts of negation present in the literature, suggesting that contextual factors are crucial for determining the kind of cognitive dynamics displayed. We conclude by drawing broader lessons about theories of cognition from the case of negation. (shrink)

This essay proposes that Polanyi’s tacit knowing – specifically his conception of tacit knowing as cognitive contact with reality – should be construed as fundamentally a knowing by acquaintance – a relational knowing of reality, rather than merely the underlying subsidiary component of explicit representational knowledge. Thus construed, Polanyi’s theory that tacit knowing is foundational to all human knowing is more radical than is often supposed, for it challenges the priority status of explicit representational knowledge relative to tacit acquaintance knowledge, (...) which has been the dominant paradigm for most of the Western epistemological tradition. (shrink)

In this paper, I present an analysis of those aspects of Karl Polanyi's social and political thought that relate to environmentalism and ‘green’ politics today. I discuss whether or not he prefigured the degrowth movement, before focusing on his understanding of the New Deal (1933–1939). At the time of writing, the prospect appears likely of a return, at a global scale, of economic slump, mass unemployment and ecological crisis, the background conditions to which Franklin D. Roosevelt's New Deal was responding (...) on the national scale. The paper concludes by drawing lessons from this comparison for possible Green New Deals. (shrink)

My intent is to paint in rather broad strokes Bill Poteat’s intellectual agenda, as I came to understand it, and how Michael Polanyi fit into that agenda for Poteat alongside other major intellectual mentors. Bill’s agenda was to expose critically and, so far as possible, to counter the fateful consequences of what he called the “prepossessions of the European Enlightenment” regarding human knowing, human doing, and human being. Although his work involved conceptual analysis, the nature of this conceptual-archaeology was far (...) more profound than what usually goes by the name “conceptual analysis” or “cultural conceptual analysis.” In effect it sought first to bring to light how the conceptual resources by which modern intellectuals reflectively consider anything, fatefully result in a state of self-abstractedness – indeed, a kind of culturally constituted insanity – that loses touch with the actual, concrete object of one’s concern, with one’s actual concrete self, and with the wellsprings of one’s intellectual passion and creativity. Second, Bill sought to cure this cultural insanity, person by person, by ushering his students and readers into re-placement of themselves into themselves, in possession of themselves, within the concrete context of their embodied personhood. Poteat called attention to the way that our powers of reflection quite systematically forget their contextual rootedness in this cultural matrix and, beneath that, in our lived bodies – ultimately in our personhood. Polanyi served to assist Poteat in this endeavor, I believe, as much as, or more than, did any other of Poteat’s several intellectual mentors. (shrink)

This article is a review of Deep Postmodernism by Jerry H. Gill. In this book Gill juxtaposes and compares the philosophies of Whitehead, Wittgenstein, Merleau-Ponty, Polanyi, and Austin—philosophies that on the surface are very different but, examined closely, are remarkably complementary and convergent in respect of their challenging and revising key assumptions of modern thought relating to topics of reality, linguistic meaning, embodiment, and knowing. Their critiques resonate with several of the critiques of well-known postmodern thinkers but go deeper by (...) reconstructing the key assumptions in question. I compare Gill’s conception of deep postmodern philosophy with Polanyi’s conception of post-critical philosophy. Gill’s book is significant in setting out in one place the beachhead that these five thinkers have established in overcoming the philosophically sterile dead-ends that modernist and postmodernist thought have bequeathed us. (shrink)

The modern critical tradition’s strategy for defeating the demon of self doubt and securing certainty, as Hannah Arendt has written, restricts serious candidates for belief to those whose conditions of truth can be rendered wholly immanent to focal consciousness within a point of view that is simply taken for granted. Thereby it forecloses the possibility of recognizing the partiality of its own perspective vis-a-vis that of others, taking into account the relevant perspectives of other persons, and reaching any kind of (...) sense in common between perspectives. The institutionalization of this strategy in 20th century academic life is amply and insightfully documented in Bruce Wilshire’s Moral Collapse of the University. Michael Polanyi, in his writings, adumbrates a post-critical intellectual ethos in whichthe making of sense in common between persons of differing perspective is central to the enterprise of teaching, learning, and research. Key elements of such an intellectual ethos are articulated and explored. (shrink)

This paper essays an account of William H. Poteat's teaching--both what he taught and how he taught--as an effort to bring his students to a realization of the bankruptcy of the modern critical sensibility and help them negotiate a transition to a post-critical intellectual sensibility. Enigmatic aspects of his teaching become intelligible through considering them in light of traditional disciplines of spiritual formation.

Leslie Stephen (1832–1904) was a writer, philosopher and literary critic whose work was published widely in the nineteenth century. As a young man Stephen was ordained deacon, but he later became agnostic and much of his work reflects his interest in challenging popular religion. This two-volume work, first published in 1876, is no exception: it focuses on the eighteenth-century deist controversy and its effects, as well as the reactions to what Stephen saw as a revolution in thought. Comprehensive and (...) full of detailed analysis, this is an important work in the history of ideas. Volume 2 focuses on eighteenth-century moral philosophy, political philosophy and literature, and on the literary and religious reactions to the revolution in thought. Utilitarianism is discussed at length, as well as the work of thinkers such as Shaftesbury, Mandeville, Burke and Adam Smith. (shrink)

This brief essay summarizes the content of the current issue of Tradition and Discovery which is devoted to a symposium on similarities between and relevance to each other of the work of Blythe Clinchy, one ofthe authors of Women’s Ways of Knowing, and the work of Michael Polanyi. The background of Women’s Ways of Knowing is sketched for readers without independent familiarity with it.

In her book Uneasy Virtue, Julia Driver presents an account of motive or trait utilitarianism, one that has been taken as “the most detailed and thoroughly defended recent formulation” of consequential virtue ethics. On Driver's account character traits are morally virtuous if and only if they generally lead to good consequences for society. Various commentators have taken Driver to task over this account of virtue, which she terms “pure evaluational externalism.” They object that, on Driver's account of virtue, it could (...) turn out that traits traditionally understood as pernicious are actually virtuous. While many writers have speculated about the forms new 'virtues' might take in a hypothetical world, I will argue that at least one trait that is seemingly pernicious but would have to be counted as virtuous by Driver already exists. (shrink)

Why is it that toleration can be uncomfortable for the tolerated? And how should tolerators respond to that discomfort? This paper argues that properly directed toleration can be deficient in its scope, grounds or spirit. That explains some of the discomfort in being tolerated. Beyond this, the occasions for toleration - the existence of a power to prevent and of an adverse judgment - can also make toleration sting. The paper then explores and rejects two familiar suggestions about how one (...) should respond to this discomfort: with acceptance or recognition of the tolerated. It is proposed instead that toleration should be supplemented by understanding. The nature and importance of this attitude are assessed. (shrink)

Giubilini and Minerva ask why birth should be a critical dividing line between acceptable and unacceptable reasons for terminating existence. Their argument is that birth does not change moral status in the sense that is relevant: the ability to be harmed by interruption of one's aims. Rather than question the plausibility of their position or the argument they give, we ask instead about the importance to scholarship or policy of publishing the article: does it to any extent make a novel (...) or needed addition to the literature? Giubilini and Minerva's argument is remarkably similar to one advanced by Michael Tooley in ‘Abortion and Infanticide,’ almost 40 years ago. There have been immense changes in the intervening 40 years: in the ability to diagnose conditions early in pregnancy, in genetics and in the availability of in vitro fertilization; in understanding of the capabilities of persons with disabilities; in law; in economic support and access to healthcare for pregnant women and their children; in social customs and arrangements; and even in philosophy, with developments in feminist thought, bioethics and cognitive science. Some of these changes have been for the better, but others, such as the unravelling of social safety nets, have arguably been for the worse. Any or all of these changes might give rise to moral reasons for the relevance of birth that were not available 40 years ago. These changes might also be relevant to the identification of cases, if any, in which ‘after-birth abortion’ might be considered. If context is relevant to the applicability of moral reasons—as for theorists of justice in the non-idealised world it surely should be—it is questionable whether a view of the birth-line that ignores contextualising change can be adequate. (shrink)

Who doesn't wish they hopped out of bed each feeling energized and ready to tackle whatever challenges lie ahead? In Morning Rituals, author Leslie Koren is here to help, with practices that will have readers kicking their day off right! This tidy volume offers dozens of invigorating, empowering exercises for the body and spirit: Set an intention for the day. Drink a glass of lemon water. Write morning pages. Do a set of push-ups, or a series of energizing yoga (...) poses. Pull a tarot card. Take a moment to be still, over a cup of tea or a book of poetry. Whatever rituals speak to you, do them with intention and do them regularly, and you'll find that your morning sets the tone for a brighter, calmer, more productive day. Each prompt includes straightforward instructions as well as ways to personalize and improvise the idea. This beautifully photographed book will make for a thoughtful, loving gift-perfect for Mom, a recent graduate, or someone in need of a pick-me-up, or as a way to treat yourself. (shrink)

When Putin became president at the beginning of the 21st century, Russia was in shambles. Putin saw his task to be two fold. First, to recreate the Russian state – that had been seriously weakened by Boris Yeltsin. Second, he set out to reestablish Russia as an important international actor. His approach to dealing with those two tasks was heavily influenced by his approach to dealing with political problems. He is determined, but non ideological. He believes that Russia is unique (...) and that only "Russian" solutions will resolve the country’s problems. Most of all, Putin sees himself as a "problem solver," something that comes from his years in the KGB. And while much remains to be done, he did a lot to solve Russia’s problems. The power of the state has been restored, and Russia is taken far more seriously on the international stage than it was in 2000. What is amazing, given all of the criticism he has received in the West for his "undemocratic" actions, his standings in the polls for the eight years he was in office remained above 70%, something a Western politician can only dream of. (shrink)

This paper explicates secular psychodynamic growth through the life time and meditation as routes to the transpersonal from the perspective of evolutionary developmental biology, based around a multi-line model of growth. A multi-line model raises many significant points for a transpersonal audience. Such models have been pioneered by Hunt. When set on the footing of evolutionary developmental biology and nonlinear dynamics these kind of models become all the more cogent, penetrating and far reaching, validating plurality and diversity in both the (...) process and final form of transpersonal development. The "anecdotal" accounts which Hunt reports, and which this paper adds to, can thus be amalgamated with an established and sophisticated research program . Such developments are symptomatic of a general movement in the sciences towards a non-linear paradigm, to which the transpersonal movement might have been slow to respond. (shrink)