To identify motivational factors linked to child health status that affected the likelihood of parents’ allowing their child to participate in pediatric research.

Stroke is a severe health issue, and motor recovery after stroke remains an important challenge in the rehabilitation field. Neurofeedback, as part of a brain–computer interface, is a technique for modulating brain activity using on-line feedback that has proved to be useful in motor rehabilitation for the chronic stroke population in addition to traditional therapies. Nevertheless, its use and applications in the field still leave unresolved questions. The brain pathophysiological mechanisms after stroke remain partly unknown, and the possibilities for intervention (...) on these mechanisms to promote cerebral plasticity are limited in clinical practice. In NFB motor rehabilitation, the aim is to adapt the therapy to the patient’s clinical context using brain imaging, considering the time after stroke, the localization of brain lesions, and their clinical impact, while taking into account currently used biomarkers and technical limitations. These modern techniques also allow a better understanding of the physiopathology and neuroplasticity of the brain after stroke. We conducted a narrative literature review of studies using NFB for post-stroke motor rehabilitation. The main goal was to decompose all the elements that can be modified in NFB therapies, which can lead to their adaptation according to the patient’s context and according to the current technological limits. Adaptation and individualization of care could derive from this analysis to better meet the patients’ needs. We focused on and highlighted the various clinical and technological components considering the most recent experiments. The second goal was to propose general recommendations and enhance the limits and perspectives to improve our general knowledge in the field and allow clinical applications. We highlighted the multidisciplinary approach of this work by combining engineering abilities and medical experience. Engineering development is essential for the available technological tools and aims to increase neuroscience knowledge in the NFB topic. This technological development was born out of the real clinical need to provide complementary therapeutic solutions to a public health problem, considering the actual clinical context of the post-stroke patient and the practical limits resulting from it. (shrink)

BackgroundRegularity effect can affect performance in prospective memory, but little is known on the cognitive processes linked to this effect. Moreover, its impacts with regard to aging remain unknown. To our knowledge, this study is the first to examine regularity effect in PM in a lifespan perspective, with a sample of young, intermediate, and older adults.Objective and designOur study examined the regularity effect in PM in three groups of participants: 28 young adults, 16 intermediate adults, and 25 older adults. The (...) task, adapted from the Virtual Week, was designed to manipulate the regularity of the various activities of daily life that were to be recalled. We examine the role of several cognitive functions including certain dimensions of executive functions, short-term memory, and retrospective episodic memory to identify those involved in PM, according to... (shrink)

Background Universities in Cameroon are playing an active part in HIV/AIDS research and much of this research is carried out by students, usually for the purpose of a dissertation/thesis. Student theses/dissertations present research findings in a much more comprehensive manner and have been described as the stepping-stone of a budding scientist’s potential in becoming an independent researcher. It is therefore important to verify how students handle issues of research ethics. Method Theses/dissertations on HIV/AIDS that described research studies involving the use (...) of human research participants were screened to verify if research ethics approval and informed consent were obtained and documented. The contents of the consent forms were also qualitatively analyzed. Results Of 174 theses/dissertations on HIV, ethics approval was documented in 17 and informed consent in 77. Research ethics approval was first mentioned at all in 2002 and highly reported in the year 2007. Evidence of ethics approval was found for the first time in 2005 and informed consent first observed and evidenced in 1997. Ethics approval was mostly reported by students studying for an MD and was not reported in any Bachelors’ degree dissertation. Informed consent was also highly reported in MD theses followed by undergraduate theses. Voluntary participation and potential benefits of the study were some of the common aspects dealt with in most of the consent forms. The right to discontinue participation in the study and management of residual samples were scarcely ever mentioned. Conclusions Overall, and given the current state of the art of research ethics around the world, student-scientists in Cameroon would seem to be merely kidding with research ethics. It is thus essential that training in health research ethics be incorporated in the curriculum of universities in Cameroon in order that the next generation of scientists may be better equipped with thorough knowledge and practice of HRE. This, we believe, would be one way of fighting the occurrence of research scandals, which have not yet abated significantly, especially those arising from negligence or inexcusable ignorance. (shrink)

This is the first volume of a two-volume project whose aim is to publish all the known Middle English manuscript translations of the French Somme le mi, a thirteenth-century manual of religious instruction offering teaching on the Decalogue, the seven deadly sins and their remedies, compiled by the Dominican friar Laurent of Orleans. The project extends and deepens our knowledge of the influence of this popular French text, known today only from the versions entitled The Ayen bite of Inwit (...) and The Book of Vices and Virtues, published in 1866 and 1942, respectively. This volume presents the versions extant in BL MSS Royal 18. A. x and Add. 37677; the second will cover the versions in Cambridge, Corpus Christi College, MS 494, Oxford, Bodleian Library, MS Ashmole 1286, and Oxford, Bodleian Library, MS e Musaeo 23. The texts of both volumes have been prepared with the help of the recently-published edition of the French text, a circumstance from which the earlier English editions were unable to benefit. It is likely that the versions edited here for the first time will make a considerable contribution to our understanding of the processes of textual transmission and to that of translation itself in English literary circles of the fifteenth century. (shrink)

Cognitive Science, Volume 46, Issue 9, September 2022.

Eternal recurrence and the principle of economy in Nietzscheʼs thought. This paper explores the place that the principle of parsimony occupies in Nietzscheʼs thought. I argue that the principle of parsimony is one of the criteria that allow Nietzsche to organize the many different interpretations available to us into a hierarchy. The question is whether Nietzsche can justify the use of this principle without making it a petitio principii. Oddly enough, it seems that eternal recurrence has a role to play (...) in this context. The most important problem Nietzsche has to confront is the problem of circularity. Bringing together Nietzsche’s specific conception of truth with the problem of eternal recurrence allows us to recognize that circularity provides for access to a higher density of the real. (shrink)

Résumé Où va la peinture est un livre de Laurent Marissal qui se présente à la fois comme un traité sur la peinture et comme une œuvre peinte. Les actions qu’il relate sont elles-mêmes revendiquées comme des actions picturales. L’article s’interroge sur ces usages hétérodoxes de la notion de « picturalité », tout d’abord au niveau de la mise en forme narrative du livre, puis à celui des actions que cette forme a pour dessein de relater. Une dernière partie (...) étudie la relation du travail de Laurent Marissal avec le courant du narrative art. (shrink)

The relationship between statistical mechanics and population genetics has a long history. Both take advantage of statistics to address the behavior of large groups of entities. The main objective of this article is to assess the obstacles population genetics is meeting in its claim to explain biological phenomena from the conceptual apparatus of statistical mechanics according to two recent articles. Several tools available to the latter are missing in the former. Thus, in the absence of an adequate justification of the (...) relevance of the analogy and without the satisfaction of certain basic assumptions, I argue that the explanatory strategy of the analogously based model is seriously compromised. La relation entre mécanique statistique et génétique des populations a une longue histoire. À l’instar de la première, la seconde tire profit des statistiques afin de traiter le comportement des grands ensembles d’entités. L’objectif principal du présent article est d’identifier les obstacles que rencontre la génétique des populations dans sa prétention d’explication des phénomènes biologiques à partir de l’appareillage conceptuel de la mécanique statistique selon deux articles récents. Or, plusieurs outils dont dispose cette dernière manque à la première. Ainsi, en l’absence d’une justification adéquate de la pertinence de l’analogie et sans la satisfaction de certaines hypothèses fondamentales, je soutiens que la stratégie explicative du modèle analogue est sérieusement compromise. (shrink)

Dubreuil provocatively proposes an extremist rethinking of the limits of politics - toward a break from politics, the political and policies. He calls for a refusal of politics, suggesting a form of apolitics that would make our lives more liveable. The first chapter situates the refusal of politics in relation to different contemporary theoretical attempts to renew politics, and makes the case for a greater rupture. The second moment takes up what is liveable in life by way of apolitical experience, (...) in contrast to appropriations of the collective, including a discussion of the arts. Finally, Laurent Dubreuil draws up an incomplete inventory of means, forms of existence - often frail and fleeting - that make an exit toward atopia. (shrink)

Volume 28, Issue 5, September 2020, Page 944-965.

Nuclear pre‐mRNAs must be precisely processed to give rise to mature cytoplasmic mRNAs. This maturation process, known as splicing, involves excision of intron sequences and ligation of the exon sequences. One of the major problems in understanding this process is how splice sites, the sequences which form the boundaries between introns and exons, can be accurately selected. A number of studies have defined conserved sequences within introns which were later shown to interact with small nuclear ribonucleoproteins (snRNPs). However, due to (...) the simplicity of these conserved sequences it has become clear that other elements must be involved and a number of studies have indicated the importance of secondary structures within pre‐mRNAs. Using various examples, we shall show that such structures can help to specify splice sites by modifying physical distances within introns or by being involved in the definition of exons and, lastly, that they can be part of the regulation of alternative splicing. (shrink)

The opposition between community and society set out by Collingwood in hisNew Leviathan(1942) should be compared with the distinction betweenGemeinschaftandGesellschaftthat Tönnies had introduced in 1887. The debate on ideal types of social organizations apparently pertains to «pure sociology» and was continued by Durkheim and Weber. However, Collingwood's use of this distinction may be construed as an attack on the very idea of sociology in the name of the primacy of rational will.

Cognitive forms vary considerably as a human being detaches herself from what is closest and most personal and moves to communicate — in the broad sense of taking part in a common matter — across increasing relational distances. The article proposes to deal with the variety of cognitive formats which cannot `commonize' cognition to an equal degree, relating them to a set of regimes of engagement with the world that are identified in terms of the dependency between the human agent (...) and her environment. The good that engagement aims to guarantee orients how reality is grasped and specifies the format of what constitutes relevant information. This analysis offers new insight into the composition of communities as well as persons who have to cope with the plurality of cognitive formats and engagements from the very familiar to the most public. (shrink)

“Austrian” (or “Austro-German”) philosophy of language is characterized, among other things, by the following two features: (1) Problems of language are considered within the broader framework of an intentionality-based philosophy of mind—or, to put it more precisely, questions of meaning are considered as involving a quite articulated theory of intentions; (2) several aspects of such an account are explicitly presented as inspired by or somehow already at work in the Medieval Scholastic tradition. In this study we follow the track indicated (...) by these two features and use some “Austrian” reflections on the articulation between meanings and intentions as a “heuristic filter”, as it were, to shed a new and different light on some Medieval debates in philosophy of language on the relationship between significare and intendere. It will be roughly divided into three parts. We begin by singling out some distinctive tenets of the “Austrian” strategy aimed at describing the relationship between meaning and intentions (section I), and then turn to various Medieval texts from the 13th and 14th century dealing with the two related notions of significatio and intentio (section II). The upshot of our investigation is to show how, for both “Austrian” and Medieval philosophers of language (and beyond their differences), a proper understanding of linguistic meaning—in the twofold sense of words or sentences having a lexical content and utterances having a determinate pragmatic function—presupposes an account of what one could call the “agentive intentionality”, i.e. the complex intentionality proper to practical goal-directed human behaviours. Some final remarks about outcomes, meaning, scope and perspectives opened by the method applied will conclude the study (section III). (shrink)

This article argues that many situations in social life can be analyzed by their requirement for the justification of action. It is in particular in situations of dispute that a need arises to explicate the grounds on which responsibility for errors is distributed and on which new agreement can be reached. Since a plurality of mutually incompatible modes of justification exists, disputes can be understood as disagreements either about whether the accepted rule of justification has not been violated or about (...) which mode of justification to apply at all. The article develops a grammar of such modes of justification, called orders of worth (grandeur), and argues that the human capacity for criticism becomes visible in the daily occurrence of disputes over criteria for justification. At the same time, it is underlined that not all social situations can be interpreted with the help of such a sense of justice, which resides on a notion of equivalence. Regimes of love, of violence or of familiarity are systematically distinct from regimes of justification. (shrink)

While modern theories of emotion emphasize the role of higher-order cognitive processes such as semantics in human emotion, much research into emotional learning has ignored the potential contribut...

English summary: The collected essays in this volume examine the question of experience and consciousness in philosophy, from the ancient Greeks, Descartes, and German Idealism, to contemporary phenomenology. French description: Ce volume est consacre au concept de phenomene. Les etudes rassemblees se proposent de contribuer a son intelligence en revenant sur quelques-uns des moments les plus marquants de son histoire, sans pretendre a l'exhaustivite. L'ouvrage s'ouvre par deux etudes de philosophie antique. Arnaud Mace restitue tout d'abord la problematique seminale du (...) phenomene, telle qu'elle s'elabore chez les presocratiques (Homere, Anaxagore, Parmenide) et chez Platon. Baptiste Bondu etudie ensuite la question du phenomene dans l'ecole stoicienne. Suivent deux contributions qui expose, pour l'une, la philosophie cartesienne des phenomenes (Delphine Bellis) et examine, pour l'autre, les principes et les difficultes du phenomenisme de Berkeley (Luc Peterschmitt). Deux articles attestent du renouvellement de l'approche philosophique des phenomenes dans l'idealisme allemand. Francois Calori rappelle le role decisif joue par le criticisme et explicite la definition kantienne du phenomene comme objet indetermine d'une intuition empirique. Comme le souligne Olivier Tinland, Hegel compose avec le legs de la philosophie kantienne tout en deplacant le site meme de la reflexion conduite sur les phenomenes, puisqu'il refere desormais l'apparaitre a une idealite objective. Concernant la periode contemporaine, Laurent Perreau examine la redefinition du concept de phenomene operee par la phenomenologie husserlienne. Enfin, la contribution de Vincent Bontems est consacree a la philosophie de G. Bachelard: informee des developpements historiques de la science physique, cette derniere voit dans le phenomene le produit d'une construction a la fois theorique et experimentale. (shrink)

Laurent Stern here provides a concise account of the difficulties that arise within the interpretive process and in the context of interpretive conflict. Speakers and agents are expected by others to be occasionally insincere. Attempting to be tolerant of alternative interpretations, and dealing with the insincerity of others, often motivates interpreters themselves to become insincere. Accordingly, moral issues emerge for both speakers and interpreters. Interpretive Reasoning discusses such issues in the literature on interpretation. Stern offers a carefully argued account (...) of the very idea of interpretation. What are the constraints on interpretations? What are our grounds for demanding that others agree with our interpretations? How do we support our interpretations? What are the types of interpretations we encounter? How are problems of first-person authority and self-knowledge connected with interpreting? While the author argues for interpretations supported by principles rather than by the consensus of interpreters, he also shows that even well-supported interpretations may be mistaken, and that some interpretive conflicts are interminable. Although this is a book in philosophy, scholars and students in the humanities, the social sciences, and disciplines concerned with interpretive reasoning can read it profitably. (shrink)

Today, it becomes more and more common to combine services from different providers into one application. Service composition is however difficult and cumbersome when there is no common trust anchor. Hence, delegation of access rights across trust domains will become essential in service composition scenarios. This article specifies abstract delegation, discusses theoretical aspects of the concept, and provides technical details of a validation implementation supporting a variety of access controls and associated delegation mechanisms. Abstract delegation allows to harmonize the management (...) of heterogeneous access control mechanisms and to offer a unified user experience. The authors observe standardization efforts to reduce application and domain-specific delegation mechanisms, but this variety is very unlikely to completely disappear. (shrink)

In the year 308 CE, the African army raised to the purple the agens vices praefectorum praetorio Lucius Domitius Alexander. This rather unique case of a vicarius becoming emperor is deserving of investigation. Scholarly interest on the matter has traditionally focused on the broader political significance, treating Alexander as a traditional usurper. This paper argues that, contrary to traditional studies, the regime of Alexander focused on very local, African tropes. The uniqueness of the advertisement suggests that this African usurpation was (...) the product of discontent internal to Africa; in other words, it is a departure from the usurpations of the third century. The achievements of Diocletian, who supposedly stabilized the Empire, ended when he withdrew, and the rebellion of 308–310 demonstrates that there remained unaddressed tensions between the provinces and the remaining tetrarchs. (shrink)

Ce texte a déjà paru dans Intermédialités : histoire et théorie des arts, des lettres et des techniques / Intermediality : History and Theory of the Arts, Literature and Technologies, n° 16, 2010, p. 105-128, puis sur Erudit.org. Nous remercions Laurent Guido de nous avoir autorisé à le reproduire ici. Depuis une vingtaine d'années, l'idée de mondialisation s'est imposée au sein des discours et des pratiques culturelles, dans un contexte où sont apparues de nouvelles techniques d'information et de - (...) Cinéma, animation et vidéo – GALERIE – Nouvel article. (shrink)

This article is the result of collaboration between a linguist and an anthropologist. In La Troisième planète. Structures familiales et systèmes idéologiques (The Third Planet: Family Structures and Ideologies) (Todd, 1983), anthropologist Emmanuel Todd provided a world map of family types, which he used to explain the distribution of major political philosophies around the world. However, this did not explain the distribution of the family types themselves. Indeed, a concluding chapter entitled “Le Hazard” (The Effects of Chance) stated that the (...) distribution of family types did not seem to be the result of any particular economic or ecological factor and was therefore a prime example of the uncertainty principle at work. However, Laurent Sagart, a linguist specializing in Chinese dialects, noticed that this map of family types exhibited a structure well known to experts in historical linguistics and dialectology, contrasting a large, continuous zone in the center with a number of small, independent zones located around the periphery of the central zone or in isolated enclaves within it. When such maps appear in linguistic atlases, dialectologists usually conclude that the central zone was the innovative area while the peripheral and isolated zones conserved the original features. The same analysis, if applied to the map of family types, would lead to the conclusion that the communal family system in the center of the map represented a more recent innovation than the systems around the periphery. (shrink)

Laurent Le Bon, directeur du Centre Pompidou-Metz, dévoile au cours d’un entretien avec Roland Huesca l’histoire, les atours et les enjeux de l’écriture de plusieurs catalogues d’expositions : à l’affiche Dada, Chefs-d’œuvre ?..

Guillaume St-Laurent | : Dans ses récentes méditations philosophiques, Claude Romano soutient non seulement que la phénoménologie ne devrait plus être cartésienne, mais qu’elle ne peut plus l’être, car un doute universel serait lui-même foncièrement absurde du point de vue phénoménologique. L’objectif du présent essai est de contester qu’une telle réfutation phénoménologique du cartésianisme soit possible. En ce sens, nous soutiendrons que les arguments anti-sceptiques de Romano s’avèrent insuffisants parce que le doute hyperbolique est une possibilité de pensée qui, (...) bien que spéculative, demeure à la fois intelligible et plus radicale que toute description d’essence ou « réduction eidétique ». | : In his recent philosophical contributions, French phenomenologist Claude Romano maintained not only that phenomenology should not be Cartesian, but that it cannot be Cartesian because the very idea of a universal doubt would be utterly absurd from a phenomenological perspective. Our objective is to show that such a phenomenological refutation of Cartesianism is impossible. After reviewing the two main anti-skeptical arguments propounded by Romano, we will support a simple critical thesis : the hyperbolical doubt is an irreducible possibility of thought which, although “speculative,” remains nevertheless actual and more radical than any phenomenological description. (shrink)

Resumé On a coutume de considérer qu’il y a un revirement complet qui s’opère chez Fichte entre ses Considérations sur la Révolution française de 1793 et son Fondement du droit naturel de 1796 en vertu de ce que le droit naturel et la morale ne sont pas dissociés dans la première œuvre et le deviennent complètement dans la seconde. Sans doute, le droit naturel est bien posé en 1793 comme l’expression de la loi morale dans les phénomènes, au lieu qu’il (...) est affirmé comme une science distincte de la morale en 1796. Il y aurait donc là une évolution bien connue de sa philosophie et non un problème. Pourtant, c’est faire fi de la complexité de la rationalité juridique chez Fichte que de s’en tenir à une simple lecture discontinuiste. Cet article voudrait montrer que ces deux œuvres que l’on oppose traditionnellement ne représentent pas deux visions inconciliables de la rationalité juridique, mais plutôt deux aspects complémentaires de la même rationalité juridique. En effet, selon que le Moi est pris sous le rapport de sa destination ou de sa genèse, deux perspectives différentes mais conciliables s’ouvrent sur le droit. (shrink)

Laurent Henninger intervenant sur les « révolutions militaires » (notion située au carrefour du débat historique lancé dans les années 1980 par Geoffrey Parker – en polémique avec Jeremy Black – et du débat stratégique américain dans les années 1990) souligne que les avancées dans l’art de la guerre ont été depuis cinq siècles une des composantes majeures de la barbarisation et du totalitarisme. La notion de « révolution militaire » est aujourd’hui contestée par ceux qui y voient un (...) outil interprétatif de trop longue durée et lui préfèrent l’idée de « mutations militaires » (selon laquelle l’accumulation de changements millimétriques sur la longue durée débouche sur des ruptures). Après avoir passé en revue la première révolution militaire – XVe-XVIIe siècles – fondée sur la mise à distance de la cavalerie grâce à l’infanterie nouvelle, à l’artillerie du champ de bataille, Henninger s’interroge sur le critère discriminant pour qualifier les nouvelles guerres de la Renaissance (l’hyperviolence n’en est pas un à ses yeux) et voit dans les armes à feu la vraie rupture car elles influent de façon radicale sur la peur et le courage des combattants et sont source d’une véritable « inhumanité » dans la mesure où leur feu est « imparable ». Il insiste sur l’émergence d’un nouveau type de courage guerrier non archaïque et plus « stoïcien » marqué par l’acceptation de la mort. Dans cette perspective, l’« inhumanisation » technique porterait en elle la possibilité de la barbarisation. L. Henninger développe ensuite cette thèse à partir de l’examen des guerres mécanisées de la période 1860-1950 en s’attardant sur la guerre de Sécession puis sur la Grande Guerre. Il relie aussi la question du totalitarisme à la réflexion sur les « bombardements stratégiques massifs » et les débuts de la dissuasion nucléaire (terme qui ne s’impose que vers 1960). Il conclut en insistant sur le fait que, selon lui, la brutalisation des conflits naît toujours d’un retard de la pensée de la guerre et sur le paradoxe d’une culture occidentale qui produit en même temps barbarie de la guerre et codes qui tentent de l’enrayer. (shrink)

On a souvent résumé la présence importante des avocats dans la vie politique française sous la III e République à travers l’expression de « République des avocats. » De manière plus complexe, il s’agit de montrer comment les avocats sont au cœur, dans les premières décennies de la République, de la construction d’un champ politique marquée par la codification des règles électorales et une certaine démocratisation du personnel politique. Dans les décennies qui suivent, on note une diversification des formes d’investissement (...) du barreau en politique, moins marqué par l’investissement dans le champ politique proprement dit que par l’engagement à travers la défense judiciaire de causes. (shrink)

La famille Poincaré trouve ses racines en Lorraine, dans les départements de Meurthe-et-Moselle, de la Meuse et des Vosges. Arrancy-sur-Crusne, Bar-le-Duc, Landaville, Longuyon, Lunéville, Nancy, Neufchâteau, Remenoncourt, Xirocourt sont quelques-unes des communes ayant vu naître des ancêtres des deux Poincaré les plus connus, Henri et Raymond. Cet article propose une histoire de la famille d’Henri Poincaré sur le temps long et prend appui sur une vaste synthèse des informations généalogiques existantes. Dans un premier temps j’explore rapidement les origines anciennes du (...) nom « Poincaré » et certaines branches indirectes de la famille ; j’analyse ensuite de manière plus fine les parcours des acteurs principaux de la branche directe, en particulier ceux du père, de l’oncle et du grand-père paternels d’Henri Poincaré. Je termine ce parcours en me focalisant rapidement sur les mariages et les descendants respectifs d’Henri Poincaré et de sa sœur Aline. Un tel essai est structuré autour d’une double ambition : d’une part, apporter une contribution à la biographie de Poincaré centrée sur la sphère privée ; d’autre part, caractériser finement le milieu social dans lequel Poincaré a pu évoluer au cours de sa vie. (shrink)

Au cours de notre histoire évolutive, le cerveau humain a été modelé en profondeur par et pour la vie en société. Nous sommes ainsi naturellement dotés de dispositions cognitives qui nous permettent de naviguer dans notre environnement social et contraignent la manière dont nous nous y comportons. Les sciences cognitives contemporaines nous offrent une compréhension de plus en plus détaillée des rouages de cette cognition sociale naturelle. Ces connaissances nouvelles doivent intéresser tous ceux qui cherchent à comprendre le fonctionnement et (...) les mystères de notre monde social. Il est donc temps de dépasser la méfiance que les sciences expérimentales suscitent encore trop souvent en sociologie. Proposant un parcours au travers de la psychologie cognitive, de la psychologie du développement, des neurosciences et de la primatologie, cet ouvrage expose ce que ces sciences sont susceptibles d’apporter à la sociologie. (shrink)