In this work a mechanistic explanation of the classical algae growth model built by M. R. Droop in the late sixties is proposed. We first recall the history of the construction of the “predictive” variable yield Droop model as well as the meaning of the introduced cell quota. We then introduce some theoretical hypotheses on the biological phenomena involved in nutrient storage by the algae that lead us to a “conceptual” model. Though more complex than Droop’s one, our model remains (...) accessible to a complete mathematical study: its confrontation to the Droop model shows both have the same asymptotic behavior. However, while Droop’s cell quota comes from experimental bio-chemical measurements not related to intra-cellular biological phenomena, its analogous in our model directly follows our theoretical hypotheses. This new model should then be looked at as a re-interpretation of Droop’s work from a theoretical biologist’s point of view. (shrink)

Legal decision-support systems have the potential to improve access to justice, administrative efficiency, and judicial consistency, but broad adoption of such systems is contingent on development of technologies with low knowledge-engineering, validation, and maintenance costs. This paper describes two approaches to an important form of legal decision support—explainable outcome prediction—that obviate both annotation of an entire decision corpus and manual processing of new cases. The first approach, which uses an attention network for prediction and attention weights to highlight salient case (...) text, was shown to be capable of predicting decisions, but attention-weight-based text highlighting did not demonstrably improve human decision speed or accuracy in an evaluation with 61 human subjects. The second approach, termed semi-supervised case annotation for legal explanations, exploits structural and semantic regularities in case corpora to identify textual patterns that have both predictable relationships to case decisions and explanatory value. (shrink)

This paper provides a series of reflections on making the case to senior leaders for the introduction of clinical ethics support services within a UK hospital Trust at a time when clinical ethics committees are dwindling in the UK. The paper provides key considerations for those building a case for clinical ethics support within hospitals by drawing upon published academic literature, and key reports from governmental and professional bodies. We also include extracts from documents relating to, and annual reports of, (...) existing clinical ethics support within UK hospitals, as well as extracts from our own proposal submitted to the Trust Board. We aim for this paper to support other ethicists and/or health care staff contemplating introducing clinical ethics support into hospitals, to facilitate the process of making the case for clinical ethics support, and to contribute to the key debates in the literature around clinical ethics support. We conclude that there is a real need for investment in clinical ethics in the UK in order to build the evidence base required to support the wider introduction of clinical ethics support into UK hospitals. Furthermore, our perceptions of the purpose of, and perceived needs met through, clinical ethics support needs to shift to one of hospitals investing in their staff. Finally, we raise concerns over the optional nature of clinical ethics support available to practitioners within UK hospitals. (shrink)

There is a popular hypothesis that performance on implicit and explicit memory tasks reflects 2 distinct memory systems. Explicit memory is said to store those experiences that can be consciously recollected, and implicit memory is said to store experiences and affect subsequent behavior but to be unavailable to conscious awareness. Although this division based on awareness is a useful taxonomy for memory tasks, the authors review the evidence that the unconscious character of implicit memory does not necessitate that it be (...) treated as a separate system of human memory. They also argue that some implicit and explicit memory tasks share the same memory representations and that the important distinction is whether the task (implicit or explicit) requires the formation of a new association. The authors review and critique dissociations from the behavioral, amnesia, and neuroimaging literatures that have been advanced in support of separate explicit and implicit memory systems by highlighting contradictory evidence and by illustrating how the data can be accounted for using a simple computational memory model that assumes the same memory representation for those disparate tasks. (shrink)

Up till now, China has not enacted any legal mechanisms governing certification or supervision for ethics committees. This article analyses deficiencies in the protection of subjects in clinical drug trials under China’s current laws and regulations; it emphasizes that investigators, as practitioners who have direct contact with subjects, play significant roles in protecting and safeguarding subjects’ rights and interests. The paper compares the status quo in China in this area to that of other countries and discusses ways China might enhance (...) the protection of rights and interests of trial subjects, such as enhancing the ethical awareness of investigators through training, improving laws and regulations, and strengthening the communication between investigators and ethics committees. (shrink)

Il importe de situer les enjeux humains de ce mouvement que d'aucuns qualifient de « nouvel ordre mondial » : quel souci de l'être humain en tant que tel manifeste-t-il ? L'homme est un être d'appartenances individuelles et collectives, il s'éprouve dans sa liberté et dans sa participation à l'histoire qui se fait. La société qui s'annonce sera-t-elle pour lui, offerte à son engagement, ou contre lui, le contraignant à se soumettre ou à se démettre ? Des penseurs contemporains montrent (...) que l'homme se construit en habitant l'écart entre particulier et universel , individualité et solidarité , « territoire » et « planète » . Comment cette « dialectique » pourra-t-elle s'exercer demain dans un univers aux contours flous et aux logiques opaques? On ne peut fonder un « contrat » éthique et politique avec d'autres si le temps social, économique ou culturel dissout les particularités et rend l'avenir improbable. Il se pourrait que la mondialisation oblige les « instances de sens » à faire mémoire, à raconter comment on devient hommes ensemble dans la complexité d'une histoire à faire. L'urgence est à la transmission. It is important to situate the human stakes of this movement that some people qualify as « new world order » : what concern of the human being as such does it manifest ? Man is a being of individual and collective belonging. He tests himself in his freedom and in his participation in history in the making. Will future society be for him, inviting him to participate, or against him, forcing him to submit or to give up ? Contemporaneous thinkers show that man constructs himself in living the gap between the particular and universal , individuality and solidarity , « territory » and « planet » . How can this « dialectic » be practiced tomorrow in a universe with vague outlines and opaque logics ? One cannot establish an ethical and political « contract » with others if the social, economic, or cultural time dissolves particularities and makes the future improbable. Il is possible that globalization obliges the « moments of sense » to remember, to tell about how we become human together in the complexity of a history to be made. The urgency is the transmission. (shrink)

The Suffering of the Impassible God provides a major reconsideration of the notion of divine impassibility in patristic thought. The question whether, in what sense, and under what circumstances suffering may be ascribed to God runs as a golden thread through such major controversies as Docetism, Patripassianism, Arianism, and Nestorianism. It is commonly claimed that in these debates patristic theology fell prey to the assumption of Hellenistic philosophy about the impassibility of God and departed from the allegedly biblical view, according (...) to which God is passible. As a result, patristic theology is presented as claiming that only the human nature of Christ suffered, while the divine nature remained unaffected. Paul L. Gavrilyuk argues that this standard view misrepresents the tradition. In contrast, he construes the development of patristic thought as a series of dialectical turning points taken to safeguard the paradox of God's voluntary suffering in the flesh. For the Fathers the attribute of divine impassibility functioned in a restricted sense as an apophatic qualifier of all divine emotions and as an indicator of God's full and undiminished divinity. The Fathers at the same time admitted qualified divine passibility of the Son of God within the framework of the Incarnation. Gavrilyuk shows that the Docetic, Arian, and Nestorian alternatives represent different attempts at dissolving the paradox of the Incarnation. These three alternatives are alike in that they start with the presupposition of God's unrestricted impassibility: the Docetic view proposes to give up the reality of Christ's human experiences; the Arian position sacrifices Christ's undiminished divinity; while the Nestorian alternative isolates the experiences and sufferings of Christ's humanity from his Godhead. In contrast to these alternatives, the mind of the Church succeeded in keeping God's transcendence and undiminished divinity in tension with God's intimate involvement in human suffering. It is precisely because God's divinity and transcendence are never lost in suffering that the Incarnation becomes a genuine act of divine compassion, capable of transforming and healing the human condition. (shrink)

On the life and works of ancient Jaina philosophers.