In this study, 191 subjects, 93 male and 98 female undergraduate business students, were asked to respond to a 51 item questionnaire to examine their perception of what constituted a "just society". The subjects agreed on 16 characteristics which a just society would have. Out of 51 there were only 10 statements whereon average responses showed significant differences based on gender.

Adoption of technology, a research topic within the Information Systems area, is usually studied at two levels: organizational level and user level. This paper examines the range of methods used for studying technology adoption issues at both these levels. The approaches were selected after conducting a review of 48 articles on technology adoption and usage, published in peer reviewed journals between 1985 and 2003. The journals reviewed include the MIS Quarterly, Information Systems Research, European Journal of Information Systems, Information Systems (...) Journal, and other relevant journals in the IS area. The findings suggest that the survey method was used predominantly when investigating the topics of user adoption and the usage of technology. In contrast, the case study method is the most widely used when examining adoption issues at the organizational level. (shrink)

This paper aims to investigate the effect of gamification in engaging and motivating consumers for online shopping and also the use of gamification to enhance sales. Moreover, this study has also explored the ethical concerns in gamified marketing. This is a qualitative study to investigate the effect of gamification during online shopping and the ethical issues involved in gamified marketing. Semi-structured interviews with ten gamification experts are conducted and analyzed through NVivo. The themes that emerged from qualitative analysis are the (...) applicability of gamification in online retail, consumer experiences in gamified retail, and ethics and challenges in gamification. Semantic analysis is performed, and as per the viewpoint of the gamification experts, it was found that the perception of ethics in gamification is negative, which shows that there are many unethical practices in gamified marketing. This paper shows that by focusing on every relational aspect of consumer engagement, retailers can build trust and retain their most valuable stakeholders — the customers, thereby addressing the crucial negative concerns of gamified marketing. This research is one of its types to explore the significant ethical issues that affect consumers in the retail context. The undertaking of this study in an emerging economy adds further insight into gamified retail literature by generalizing the applicability of gamified studies across geographic contexts. (shrink)

Research papers on Prakrit Jaina canonical literature.

In lieu of an abstract, here is a brief excerpt of the content:Omissions and Chronological ComplexitiesJyoti Mohan (bio)The stated purpose of Chinese and Indian Ways of Thinking in Early Modern European Philosophy: The Reception and the Exclusion by Selusi Ambrogio is "to examine the European understanding of China and India within the histories of philosophy from 1600 to 1744."1 Specifically, Ambrogio sets out to investigate the antecedents of the "othering" of non-Western philosophies. How far back did the notion go, that (...) non-Western philosophies were inferior? While Ambrogio often extends his argument to non-Western philosophies in general, in this monograph he examines only what he defines as "orientalist" philosophies—the philosophies of India and China. Since Ambrogio is investigating the histories of philosophy written in Europe, this choice makes sense: India and China were the two philosophical giants that most European philosophers needed to include in their works in order to claim to be universalist. No philosopher who wrote about world philosophies—and by extension no historian of philosophy—could ignore India and China, whether it was to dismiss the philosophies emanating from these geographic regions as inferior, or to extol them as proof that Europe was not the birthplace of "original thought."Ambrogio has chosen a time span from 1600 to 1744 c.e. to represent "the year 1600 … [,] the publication of Barbaricae philosophae antiquitatum by Otto van Heurn[,] and 1744[,] the year of the publication of the last book of the Historia critica by Jakob Brucker."2 Within the limits of this time [End Page 220] span, Ambrogio examines the work of several scholars who included Indian and Chinese philosophies in their "world histories of philosophies" and delineates three major historiographical trends. His rationale for ending his study with Brucker's work is that after this eighteenth-century opus, "Asians were usually excluded from the histories of philosophy."3 This time span seems puzzling to me. I know that most, if not all, of the authors Ambrogio cites had successors in their individual traditions well into the nineteenth century, if not the twentieth. While many histories of philosophy focused solely on the Western and classical traditions (as they did during the period under review by Ambrogio as well), the work of historians and scholars on Orientalist philosophies continued to multiply. To the extent that Ambrogio diligently studies his sources and constructs his argument, his work is commendable, but as a historian my questions for Ambrogio have to do with the underlying rationale for the time span he has chosen, and, by that extension, by the choices of his sources. Below I collect evidence that Asians continue to be included in the histories of philosophy past 1744, and in so doing suggest that this fact has an impact on his historiographical model.For instance, I would like to understand why, in his choice of sources, he has omitted all colonial works, especially since he engages with the argument that descriptions and understandings of Indian and Chinese philosophies were meditated through lenses of proselytization and of conquest. Granted, he is beginning with historians of philosophy, but as the eighteenth and nineteenth centuries progressed, historians also diversified their writings—as Ambrogio acknowledges—into histories of religion for instance. The connections between, and descriptions of, non-Western religions and philosophies were so muddled that it is impossible to separate them, save by attending to the titles of individual authors' works as being about religion or philosophy, respectively.The contents of such works are so closely related, at least in the Indian context, that contemporary historians, especially of the colonial period and of Indology, do not quibble over whether these works are about religion or philosophy. For instance, Paul Masson-Oursel wrote in 1923 that the development of Indian philosophy was integral to and proceeded alongside the development of religion.4 Systems of philosophical thought in India operated within larger systems of religious practice. Based on this model, Masson-Oursel describes the development of Indian philosophy as proceeding from the needs of religion. So, for example, he theorized that the mix of an Indo-Iranian religion and a pastoral, fire-worshipping people with an older indigenous Dravidian culture of agriculture, Goddess worship, and belief in amulets, spells, talismans, and other... (shrink)

This article examines the role of Harlequin and Mills and Boon romance novels in the lives of young, single, middle-class women readers in urban India. The article focuses on the readers' interpretations of the novels given the differences in the sites of production of the romance novels and the sociocultural context of reception. Three themes are explored in this study: the influence of romance novels on the readers' expectations of marital sexuality and gender role patterns, the limitations of novels in (...) dealing with the social uncertainties that face the readers as young women in Indian culture, and the generation of readers' social anxieties due to the difference between the content of the novels and the sociocultural context in which they are read. The article concludes with a discussion of its implications for understanding global forms of culture, contested meanings of culturally transposed texts, and the shaping of popular cultural practices in a transnational arena around vectors of gender and socioeconomic class. (shrink)

BackgroundNeuropsychological profile of Indian Duchenne muscular dystrophy subjects remains unidentified and needs to be evaluated.MethodsA total of 69 DMD and 66 controls were subjected to detailed intelligence and neuropsychological assessment. The factor indexes were derived from various components of Malin’s Intelligence Scale for Indian Children and Rey Auditory Verbal Learning Test.ResultsPoor verbal and visual memory profiles were demonstrated by DMDs, which include RAVLT-immediate recall, RAVLT-delayed recall, Rey–Osterrieth complex figure test -IR, and RCFT-DR. RAVLT-memory efficiency index demonstrated poor verbal memory efficiency. (...) Significant differences in the functioning of working memory axis [RAVLT T1, recency T1, Digit Span Backward ] were observed along with reduced performance in visuomotor coordination, visuospatial, and visual recognition abilities. Block designing efficiency index and attention fraction showed a normal performance in DMD kids.ConclusionWorking memory deficits were found to be the crucial element of cognitive functioning in DMD cases. Working memory interventions may be beneficial to improve the neuropsychological profile in DMD. (shrink)

We examine the key elements of board diversity (or heterogeneity) amongst listed companies operating in an emerging economy (Mauritius) and the extent to which these influence financial performance. Specifically, we ask whether there is evidence of tangible benefits in pursuing a strategy of board diversity in terms of gender-, age-, educational background and independence in a corporate context which has long been dominated by family-led and ‘closed’ boardrooms. In light of recent corporate governance developments which appear to foster greater diversity, (...) we examine data from the 2007 annual reports of all 42 companies listed on the Stock Exchange of Mauritius. We find that (i) women remain poorly represented on boards (ii) there is a relatively satisfactory level of heterogeneity in terms of educational background, age and independence in relation to developed countries. We also find significant regression coefficients for all four variables in terms of their impact on short-term performance. However, these relationships are characterised by both negative and positive impacts thereby leading to discussions on the validity of a strict heterogeneous or homogeneous board composition in the context of a developing economy. (shrink)

The encounter of the cognitive apparatus with the phenomenal world had led to the emergence of independent thought processes either based on scientific method of enguiry or on meditative experiences. In the course of time these have developed into a systematized body of knowledge. They purport to provide peace and happiness, but when seduced by power a distorted value structure has been legitimized. The plethora of evidences suggest the 'self' has been incapacitated for long. The scientific experiences have been given (...) supreme status. The paper stresses the need to attain a beginner's mind so that looking within and looking without no longer remain intangible goals of education. The naodalities have been discussed to escape the bonds of conceptual limitations. Finally, it is suggested that this constructive role of optimizing the oppor tunities for formation of intellect, which moves beyond conventional intellectualism, will evolve into a com passionate world-serving intellect, and pave the way for peace and harmony in this turbulent world. (shrink)

Study of psychology with references to Ayurveda.

Thomas Kelly's book 'Bias: A philosophical study', is a philosophical exploration of the phenomena of bias and our practice of attributing it. He delves into the multifaceted nature of bias and offers a norm theoretic account for conceptualizing the phenomenon as typically involving "systematic departures from the norms". As a topic of inquiry, bias has attracted comparatively less attention in philosophy than in other disciplines like psychology and statistics. Hence, this book is an interesting and relevant read. Scholars working in (...) the areas of ethics, epistemology and social epistemology can greatly benefit from it. Practitioners of AI can also gain valuable insights from the study of bias. -/- In my review of the book, I provide a critical summary of Kelly's main arguments while acknowledging its fruitfulness in understanding bias. (shrink)

Dark patterns have received significant attention in literature as interface design practices which undermine users’ autonomy by coercing, misleading or manipulating their decision making and behavior. Individual autonomy has been argued to be one of the normative lenses for the evaluation of dark patterns. However, theoretical perspectives on autonomy have not been sufficiently adapted in literature to identify the ethical concerns raised by dark patterns. The aim of this paper is to conceptualize user autonomy within the context of dark patterns. (...) In this paper, we systematically review 151 dark patterns from 16 taxonomies to understand how dark patterns threaten users’ autonomy. We demonstrate through this analysis that implications for autonomy arise along four dimensions, because autonomy itself can be understood as subsuming several distinguishable concepts. These are agency, freedom of choice, control and independence. We argue that an assessment of whether a design pattern qualifies as ‘dark’ should account for the sense in which autonomy is threatened, as individuals’ rights and expectations of autonomy vary in various contexts and depend upon the interpretation of autonomy. This paper aims to contribute to the development of the normative lens of individual autonomy for the evaluation of dark patterns, as well as for persuasive design more broadly. (shrink)

Self-discipline, ethics, character, and philosophy in Hindu poetry; criticism to Bhagavad Gita, Nītīśāstra, Sāra-samuccaya, etc.

This article critically evaluates the process of technology transfer from developed to developing countries. It considers market-based policies contained in the United Nations Framework Convention on Climate Change, which are proposed as tools to promote the transfer of technologies that can abate greenhouse gas emissions contributing to climate change. It uses the case of India to exemplify the conditions that exist and issues that arise in a rapidly developing country that is a recipient of such investments. It contests the claim (...) that such market-based strategies embodied in the present climate policy framework can facilitate the transfer of technologies that offer ecologically sustainable and socially equitable solutions for developing countries. (shrink)

Digital business has marked an era of transformation, but also an unprecedented growth of cyber threats. While digital explosion witnessed by the banking sector since the COVID-19 pandemic has been significant, the level and frequency of cybercrimes have gone up as well. Cybercrime officials attribute it to remote working—people using home computers or laptops with vulnerable online security than office systems; malicious actors relentlessly developing their tactics to find new ways to break into enterprise networks and grasping defence evasion; persons (...) unemployed during the pandemic getting into hacking; cloud and data corruption; digital fatigue causing negligence; etc. This study adopts a case-based approach to explore the importance of business ethics, information sharing and transparency to build an information-driven society by scouting the case of Punjab and Maharashtra Co-operative (PMC) Bank, India. PMC defaulted on payments to its depositors and was placed under Reserve Bank of India’s directions due to financial irregularities and a massive fraud perpetrated by bank officials by orchestrating the bank’s IT systems. The crisis worsened when panic-stricken investors advanced their narrative through fake news peddled via social media channels, resulting in alarm that caused deaths of numerous depositors. It exposed several loopholes in information management in India’s deposit insurance system and steered the policy makers to restructure the same, thus driving the country consistent with its emerging market peers. The study further identifies best practices for aligning employees towards ethical behaviour in a virtual workplace and the pedagogical approaches for information management in the new normal. (shrink)

Although the path-integral formalism is known to be equivalent to conventional quantum mechanics, it is not generally obvious how to implement path-based calculations for multi-qubit entangled states. Whether one takes the formal view of entangled states as entities in a high-dimensional Hilbert space, or the intuitive view of these states as a connection between distant spatial configurations, it may not even be obvious that a path-based calculation can be achieved using only paths in ordinary space and time. Previous work has (...) shown how to do this for certain special states; this paper extends those results to all pure two-qubit states, where each qubit can be measured in an arbitrary basis. Certain three-qubit states are also developed, and path integrals again reproduce the usual correlations. These results should allow for a substantial amount of conventional quantum analysis to be translated over into a path-integral perspective, simplifying certain calculations, and more generally informing research in quantum foundations. (shrink)

Gluten ataxia is a rare immune-mediated neurological disorder caused by the ingestion of gluten. The diagnosis is not straightforward as antibodies are present in only up to 38% of patients, but often at lower titers. The symptoms of ataxia may be mild at the onset but lead to permanent damage if remain untreated. It is characterized by damage to the cerebellum however, the pathophysiology of the disease is not clearly understood. The present study investigated the neurochemical profile of vermis and (...) right cerebellum and structural changes in various brain regions of patients with gluten ataxia and compared it with healthy controls. Volumetric 3-D T1 and T1-weighted magnetic resonance imaging in the three planes of the whole brain and single-voxel 1H- magnetic resonance spectroscopy of the vermis and right cerebellum were acquired on 3 T human MR scanner. The metabolite concentrations were estimated using LC Model while brain volumes were estimated using the online tool volBrain pipeline and CERES and corrected for partial volumes. The levels of neuro-metabolites were found to be significantly lower in vermis, while N-acetyl aspartate + N-acetyl aspartate glutamate and glycerophosphocholine + phosphocholine was lower in cerebellum regions in the patients with gluten ataxia compared to healthy controls. A significant reduction in the white matter of ; reduction in the volumes of cerebellum lobe and thalamus while lateral ventricles were increased in the patients with gluten ataxia compared to healthy controls. The reduced neuronal metabolites along with structural changes in the brain suggested neuronal degeneration in the patients with gluten ataxia. Our preliminary findings may be useful in understanding the gluten-induced cerebral damage and indicated that MRI and MRS may serve as a non-invasive useful tool in the early diagnosis, thereby enabling better management of these patients. (shrink)

Seed development in this paper has been classified into the three landmark stages of cell division, organ initiation and maturation, based on morphological changes, and the available literature. The entire process proceeds at the behest of an interplay of various specific and general transcription factors (TFs). Monocots and dicots utilize overlapping, as well as distinct, TF networks during the process of seed development. The known TFs in rice and Arabidopsis have been chronologically categorized into the three stages. The main regulators (...) of seed development contain B3 or HAP3 domains. These interact with bZIP and AP2 TFs. Other TFs that play an indispensable role during the process contain homeobox‐, NAC‐, MYB‐, or ARF‐domains. This paper is a comprehensive analysis of the TFs essential for seed development and their interactions. An understanding of this interplay will not only help unravel an integrated developmental process, but will also pave the way for biotechnological applications. (shrink)

Multicultural environments require learning multiple number notations wherein some are encountered more frequently than others. This leads to differences in exposure and consequently differences in usage between notations. We find that differential notational usage imposes a significant neurocognitive load on number processing. Despite simultaneous acquisition, forty-two adult binumerate populations, familiar with two positional writing systems namely Hindu Nagari digits and Hindu Arabic digits, reported significantly lower preference and usage for Nagari as compared to Arabic. Twenty-four participants showed significantly increased reaction (...) times and reduced accuracy while performing magnitude comparison tasks in Nagari with respect to Arabic. Functional magnetic resonance imaging revealed that processing Nagari elicited significantly greater activity in number processing and attention networks. A direct subtraction of networks for Nagari and Arabic notations revealed a neural circuit comprising of bilateral intra-parietal sulcus, inferior and mid frontal gyri, fusiform gyrus and the anterior cingulate cortex (FDR p<0.005). Additionally, whole brain correlation analysis showed that activity in the left inferior parietal region was modulated by task performance in Nagari. We attribute the increased activation in Ng to increased task difficulty due to infrequent exposure and usage. Our results reiterate the role of the left intra-parietal sulcus in modulating performance in numeric tasks and highlight that of the attention network for monitoring symbolic notation mode in binumerates. (shrink)

This study aims to investigate how the English Language used by the Indian Railways is different from other registers of English, and most importantly what is the effect of this register of English upon the common people. In other words, the present study aims at viewing the variety of language used by the Indian Railway as an independent register. For the purpose of investigation, a stylistic analysis is carried out. The data for the current study are collected from the platform, (...) directives at railway premises and inside the railway-coaches. Platform announcements have been collected from various railway stations across the country. Some amount of data has been collected from the directives inside the railway coaches. (shrink)

To study the static software defect detection system, based on the traditional static software defect detection system design, a new static software defect detection system design based on big data technology is proposed. The proposed method can optimize the distribution of test resources and improve the quality of software products by predicting the potential defect program modules and design the software and hardware of the static software defect detection system of big data technology. It is found that the traditional static (...) software defect detection system design based on code source data takes a long time, averaging 65 h /day. However, the traditional static software defect detection system based on deep learning has a short detection time, averaging 35 h/day. In this article, the detection time of the static software defect detection system based on big data is shorter than that of the other two traditional system designs, with an average of 15 h/day. Because the system design adjusts the operating state of the system, it improves the accuracy of data operation. On the premise of data collection, the system inspection research is completed, which ensures the operational safety of software data, alleviates the contradiction between system and data to a high degree, improves the efficiency of system operation, reduces unnecessary operations, further shortens the time required for inspection, improves the system performance, and has higher research and operation value. (shrink)

The well-known classifier support vector machine has many parameters associated with its various kernel functions. The radial basis function kernel, being the most preferred kernel, has two parameters to be optimized. The problem of optimizing these parameter values is called model selection in the literature, and its results strongly influence the performance of the classifier. Another factor that affects the classification performance of a classifier is the feature subset. Both these factors are interdependent and must be dealt with simultaneously. Following (...) the multiobjective definition of feature selection, we have applied a multiobjective genetic algorithm, NSGA II, to optimize the feature subset and model parameters simultaneously. Comparison of the proposed approach with the grid algorithm and GA-based method suggests that the MOGA-based approach performs better than the grid algorithm and is as good as the GA-based approach. Moreover, it provides multiple solutions instead of a single solution. The users can prefer one feature subset over the other as per their requirement and available resources. (shrink)

This exploratory study investigates firms’ implementation of a new corporate governance code in Mauritius, a developing economy. The authors rely on annual report disclosures during a four-year period. The authors analyze the level of corporate engagement with the code’s requirements, including corporate social responsibility initiatives, relative to a 2004 benchmark over the three subsequent years. The study contributes to the literature in two ways. First, it provides much needed evidence of longitudinal implementation within developing economies that exhibit, or have started (...) to exhibit, a combination of ownership and control features found in more advanced economies and characterized in the literature as an “emerging governance” model. Second, the authors develop a more comprehensive assessment of implementation using a scoring system that combines trichotomous weighting of each governance component and trichotomous rating of implementation of each component. The authors argue that this system is superior to the un-weighted, dichotomous approach typically used in the literature. The analysis of weighted assessment scores for reveals a significant implementation of the code initially after 2004; but implementation began to level off by 2007 well below maximum assignable scores. Detailed requirements regarding directors’ appraisal and training, remuneration policies and remuneration information appear to be ignored by companies through 2007. A correlation analysis of the corporate governance scores and firm-based measures shows that the association between these different variables fluctuates significantly over the implementation window. (shrink)

ABSTRACT In this essay, I shall discuss Gadamer’s interpretation of Celan’s dialogical poetry in his essay “Wer bin Ich und wer bist Du?” (“Who am I and Who are You?”). One may argue that this is Gadamer’s articulation of the problem of the self-other relationship. To understand the question of self and other, it is first of all necessary to return to the poetic word from which the question arises. Speaking is, for Gadamer, the most profoundly self-forgetful action, because when (...) one speaks, one is so deeply “within the word” that one is not turned toward the word but, rather, to what one wants to say with the word. For hermeneutics, interpreting means putting oneself on the task of the poetic text. The proximity between poetizing and interpreting emerges, also in its specificity concerning the proximity between poetizing and thinking. Such a proximity, in turn, divides itself into two extremes: the word that sublates itself, and the word that stands for itself. It is hence the uncertain fullness of language, where, unsurprisingly, both poetizing and interpreting come into themselves, which constitutes the link between the one and the other. Therefore, the interpreted word, intertwined with the poetic word does not replace what it indicates, but merely points beyond itself, to what is other than itself. Both pursue a meaning that points toward an open realm. (shrink)

As information technologies have become synonymous with progress in modern society, several ethical concerns have surfaced about their societal implications. In the past few decades, information technologies have had a value-laden impact on social evolution. However, there is limited agreement on the responsibility of businesses and innovators concerning the ethical aspects of information technologies. There is a need to understand the role of business incentives and attitudes in driving technological progress and to understand how they steer the ethics discourse on (...) technology. In the information technology industry, there is an observed trivialization of ethics supported by a business driven and technology-centric approach to ethics. This trivialization rests on hardened beliefs, ideologies, and arguments which hint at reduced accountability for business and tend to individualize social responsibility. The phenomenon of ethics trivialization needs to be duly addressed to resolve the tensions between business needs and ethical concerns. This paper has identified from literature and conceptually analyzed the beliefs and ideologies underlying ethics trivialization which undermine ethics in business contexts. The paper has attempted to address the business concerns indicated by this phenomenon as well as highlight the weaknesses of its assumptions, rhetoric, and justifications. The aim of this paper is to systematically present the justifications in favor of and against the practice of ethics trivialization in the information technology domain, thereby highlighting the need to develop frameworks for assessment of ethical responsibility, accountability, and democratization of the value trade-offs involved in the design of technologies. (shrink)

Children of current generation needs to be cherished and nurtured as per future perspectives. Teachers’ own broad context of values put immense influence for value inculcation in students. The present study aims to analyze the perception of Indian and Western teacher trainees about values and the result drawn that Honesty, responsibility, respect for all and equality values have been most frequently cited by both Indian and Western trainees. On cultural issues category, Indian trainees preferred environmental issue while their counterparts to (...) economic climate issue. Assembly and discussion, using good example and reward, have been suggested as useful teaching strategies for value inculcation by both groups of trainees. (shrink)

Conceptualized outside the theoretical framing of both liberal as well as critical approaches, this book re-imagines the law by exploring the contradictions and polarities of in terms of its relationship with violence. It encompasses and interweaves themes and ideas as diverse as death penalty, community might, state sovereignty on the one hand, to animal rights, sexual consent, children's agency and LGBT rights, on the other. While acknowledging that law is fundamentally and inherently tied to violence, the objective of this eclectic (...) collection is to respond to and engage with the violence of law by exploring alternate ways of conceptualizing, reading, practising, and making the law. (shrink)

The paper is an attempt to revisit Rawls’ idea of a self, which elicits the concept of justice in the liberal tradition. Justice, as understood in the social and political context, is the basic feature of a well-ordered and rationally developed society and it is considered to be a virtue of the social institution. The liberal theory believes in the basic principle that right is prior to the good, and what is most fundamental to our personhood are not the ends (...) we choose but our capacity to choose them. Hence, in Rawls’ account of the self, absoluteness of the metaphysical priority has an edge over the absoluteness of the moral priority. The idea of an unencumbered self, in the social and historical sense, is at the core of the Kantian-Rawlsian theory of justice, which is under attack by the communitarians. Communitarians like Sandel, however, questions Rawls’ claim for the priority of right over good and maintains that liberals fail to recognize the self is ‘embedded,’ in and partly constituted by communal commitments and values which are objects of choice. In this paper, I examine communitarian critiques of Rawls’ liberal self. Further, I also refer to Rawls’ turn to the ‘political,’ which works as a ‘module’ that fits into and can be supported by a variety of reasonable comprehensive doctrines. (shrink)

Stress associated proteins (SAPs), novel A20/AN1 zinc‐finger domain‐containing proteins, are fast emerging as potential candidates for biotechnological approaches in order to improve abiotic stress tolerance in plants – the ultimate aim of which is crop‐yield protection. Until relatively recently, such proteins had only been identified in humans, where they had been shown to be key regulators of innate immunity. Their phylogenetic relationship and recruitment of diverse protein domains reflect an architectural and mechanistic diversity. Emerging evidence suggests that SAPs may act (...) as ubiquitin ligase, redox sensor, and regulator of gene expression during stress. Here, we evaluate the new knowledge on SAPs with a view to understand their mechanism of action. Furthermore, we set an agenda for investigating hitherto unexplored roles of these proteins. (shrink)