Aim: To evaluate health-related quality of life of chronic hepatitis B and hepatitis B virus related cirrhosis patients and analyzed specific differences in all dimensions of HRQoL.Methods: A total of 349 patients met selection criteria were enrolled. The 36-Item Short-Form Health Survey was adopted.Results: Results showed that the physiological HRQoL of the cirrhotic group was significantly lower than that of the non-cirrhotic group, the psychological HRQoL was also lower. HRQoL was significantly negatively correlated with liver stiffness. We further evaluated the (...) risk factors associated with poor HRQoL in HBV-related cirrhosis patients. Results showed that positive HBV DNA viral load and HCC family history were independent factors associated with HRQoL in HBV-related cirrhosis. For better risk stratification of patients, multivariable analyses were conducted to explore the independent factors that affected specific physiological and psychological HRQoL. In specific physiological HRQoL, results show that marital status, positive HBV DNA viral load and antiviral drugs were independent factors associated with physiological HRQoL in cirrhosis patients. In psychological HRQoL, only HCC family history was independent risk factors associated with psychological HRQoL.Conclusion: We found that the impaired HRQoL dimensions of HBV related cirrhosis patients differ between the various subpopulations. According to our results, risk stratification, medical decision making and personalizing interventions could be made. (shrink)

di 1 juan. Zheng lun pian -- di 2 juan. Zhe xue pian -- di 3juan. Wen hua pian -- di 4 juan. Shu xin yu sui bi pian.

Since Chinese scholars are playing an increasingly important role in shaping the national landscape of discussion on AI ethics, understanding their ethical concerns and preferred solutions is essential for global cooperation on governance of AI. This article, therefore, provides the first elaborated analysis on the discourse on AI ethics in Chinese academia, via a systematic literature review. This article has three main objectives. to identify the most discussed ethical issues of AI in Chinese academia and those being left out ; (...) to analyze the solutions proposed and preferred by Chinese scholars ; and to map out whose voices are dominating and whose are in the marginal. Findings suggest that in terms of short-term implications, Chinese scholars’ concerns over AI resemble predominantly the content of international ethical guidelines. Yet in terms of long-term implications, there are some significant differences needed to be further addressed in a cultural context. Further, among a wide range of solution proposals, Chinese scholars seem to prefer strong-binding regulations to those weak ethical guidelines. In addition, this article also found that the Chinese academic discourse was dominated by male scholars and those who are from elite universities, which arguably is not a unique phenomenon in China. (shrink)

The Gödel–Artemov framework offered a formalization of the Brouwer–Heyting–Kolmogorov semantics of intuitionistic logic via classical proofs. In this framework, the intuitionistic propositional logic IPC is embedded in the modal logic S4, S4 is realized in the Logic of Proofs LP, and LP has a provability interpretation in Peano Arithmetic. Self-referential LP-formulas of the type ‘t is a proof of a formula ϕ containing t itself’ are permitted in the realization of S4 in LP, and if such formulas are indeed involved, (...) it is then necessary to use fixed-point arithmetical methods to explain intuitionistic logic via provability. The natural question of whether self-referentiality can be avoided in realization of S4 was answered negatively by Kuznets who provided an S4-theorem that cannot be realized without using directly self-referential LP-formulas. This paper studies the question of whether IPC can be embedded in S4 and then realized in LP without using self-referential formulas. We consider a general class of Gödel-style modal embeddings of IPC in S4 and by extending Kuznetsʼ method, show that there are IPC-theorems such that, under each such embedding, are mapped to S4-theorems that cannot be realized in LP without using directly self-referential formulas. Interestingly, all double-negations of tautologies that are not IPC-theorems, like ¬¬, are shown to require direct self-referentiality. Another example is found in IPC→, the purely implicational fragment of IPC. This suggests that the BHK semantics of intuitionistic logic is intrinsically self-referential. (shrink)

殷海光向被公認為台灣自由主義知識人的典範。他以繼承與宏揚「五四」思想文化遺產為志業，提筆為劍，投注心力於鼓吹民主自由的實踐路向，對黨國威權體制製造的愚昧與壓迫，始終長鳴異議，非僅激盪人心，更可啟人深思 。 本書以殷海光闡釋自由主義理念的思想關懷為主題，以仍具現實意義並能激發讀者思考的原著為原則，收錄其著述精華十五篇，匯為一帙。編者潘光哲於每篇選文設計了「解題」與「延伸閱讀」兩個單元：前者摘述各文論說主旨 、解釋其時代或思想脈絡，期可有助於讀者掌握殷海光的論說要旨與背景；後者舉列相關主題的殷海光原著及研究成果，以便讀者按圖索驥，追查考究。本書並選刊相關圖片，以文圖並茂的方式，增加閱讀的興趣。初次「接觸」 、「閱讀」殷海光的讀者，本書應是打開殷海光的思想世界的第一扇窗。.

本书包含了英美基本逻辑教程中应该包含的全部题材,用对话的形式对逻辑的应用、纯逻辑的训练等方面的问题进行了讲解。.

China is actively deepening integration into economic cooperation in the Asia-Pacific region. The Regional Comprehensive Economic Partnership Agreement has come into force and China is one of its members. Furthermore, China is applying to join the Comprehensive and Progressive Agreement for Trans-Pacific Partnership. This study uses the Global Trade Analysis Project model to measure the impact of the RCEP and CPTPP on Gross Domestic Production, import, export, terms of trade, and social welfare of major economies under various scenarios, as well (...) as the competitive effects and complementarity of the RCEP and CPTPP. We found that the CPTPP with China’s accession and the RCEP will complement and strengthen each other and that the members of the two agreements can obtain substantial benefits. If China and the United States join the CPTPP, China’s import growth rate will be higher than its exports. This would transmit growth to other nations and help bridge the trade gap between China and the United States. (shrink)

Gender roles are anti-dichotomous and malleable social constructs that should theoretically be constructed independently from biological sex. However, it is unclear whether and how the factor of sex is related to neural mechanisms involved in social constructions of gender roles. Thus, the present study aimed to investigate sex specificity in gender role constructions and the corresponding underlying neural mechanisms. We measured gender role orientation using the Bem Sex-Role Inventory, used a voxel-based global brain connectivity method based on resting-state functional magnetic (...) resonance imaging to characterize the within-network connectivity in the brain reward network, and analyzed how the integration of the reward network is related to gender role scores between sex groups. An omnibus analysis of voxel-wise global brain connectivity values within a two-level linear mixed model revealed that in female participants, femininity scores were positively associated with integration in the posterior orbitofrontal cortex and subcallosal cortex, whereas masculinity scores were positively associated with integration in the frontal pole. By contrast, in male participants, masculinity was negatively correlated with integration in the nucleus accumbens and subcallosal cortex. For the first time, the present study revealed the sex-specific neural mechanisms underlying distinct gender roles, which elucidates the process of gender construction from the perspective of the interaction between reward sensitivity and social reinforcement. (shrink)

The resource-based model of self-regulation provides a pessimistic view of self-regulation that people are destined to lose their self-control after having engaged in any act of self-regulation because these acts deplete the limited resource that people need for successful self-regulation. The cognitive control theory, however, offers an alternative explanation and suggests that the depletion effect reflects switch costs between different cognitive control processes recruited to deal with demanding tasks. This account implies that the depletion effect will not occur once people (...) have had the opportunity to adapt to the self-regulatory task initially engaged in. Consistent with this idea, the present study showed that engaging in a demanding task led to performance deficits on a subsequent self-regulatory task only when the initial demanding task was relatively short but not when it was long enough for participants to adapt. Our results were unrelated to self-efficacy, mood, and motivation. (shrink)

The continuous increase of carbon emissions is a serious challenge all over the world, and many countries are striving to solve this problem. Since 2020, a widespread lockdown in the country to prevent the spread of COVID-19 escalated, severely restricting the movement of people and unnecessary economic activities, which unexpectedly reduced carbon emissions. This paper aims to analyze the carbon emissions data of 30 provinces in the 2020 and provide references for reducing emissions with epidemic lockdown measures. Based on the (...) method of time series visualization, we transform the time series data into complex networks to find out the hidden information in these data. We found that the lockdown would bring about a short-term decrease in carbon emissions, and most provinces have a short time point of impact, which is closely related to the level of economic development and industrial structure. The current results provide some insights into the evolution of carbon emissions under COVID-19 blockade measures and valuable insights into energy conservation and response to the energy crisis in the post-epidemic era. (shrink)

Media guidelines on safe suicide-related reporting are within the suicide prevention armamentarium. However, implementation issues beleaguer real-world practice. This study evaluated the perspectives of the Malaysian media community, persons with lived experience of suicidal behavior, and mental health professionals on suicide-related reporting in terms of the impact, strategies, challenges, and the implementation of guidelines on safe reporting. Three focus group discussions of purposively sampled Malaysian media practitioners, PLE, and MHP were audio-recorded, transcribed, coded and thematically analyzed. Inclusion criteria were: English (...) fluency, no clinical depression or suicidal ideation, no recent previous suicide attempts or suicide bereavement. Three major themes emerged: Unsafe Reporting; Impact; and Safe Reporting. Most described current reporting as unsafe by being potentially triggering to media users and may contribute to contagion effect. Positive impacts identified included raised awareness toward suicide and its prevention. Unsafe reporting was attributed to inadequate awareness, knowledge, and guidance, lack of empathy and accountability, job-related factors, popularity-seeking, lack of monitoring and governance, and information source with unsafe content. Majority agreed on how suicide stories should be framed to produce a safe report. The media community diverged on how detailed a suicide story should be. Safe reporting challenges included difficulties in balancing beneficial versus harmful details, social media ubiquity and its citizen reporters. Participants suggested these safe reporting strategies: stakeholder engagement, educational approaches, improving governance and surveillance, and guidelines revision. Most acknowledged the relevance of guidelines but were unaware of the existence of local guidelines. Implementation challenges included the dilemma in balancing media industry needs vis-à-vis safe reporting requirements, stakeholder engagement difficulties and social media regulation. There is poor awareness regarding safe suicide-related reporting across all groups. PLE and MHP were negatively impacted by current unsafe messaging which aggravated trauma and grief reactions. Postvention support gaps for mental health professionals were highlighted. Safe reporting promotion strategies should include stakeholder engagement to increase awareness on minimizing Werther and maximizing Papageno effects. Strategic re-examination and dissemination of local media guidelines to address new media issues, and effective surveillance mechanisms, are crucial in sustainable improvement of safe reporting practices. (shrink)

本书重点讲述老子的“为学日益,为道日损”,让老子的“道中之道”回到我们的日常生活中,并由此及彼,触类旁通。.

While business ethics has generated a great deal of research internationally over the last few decades, academic reviews of the business ethics literature remain limited. Moreover, there has been little attempt to date to analyze this literature specifically in the Greater China region, which has been experiencing rapid socioeconomic growth and dynamic evolution of business ethics in recent decades. This paper addresses this research gap by undertaking a comprehensive and critical appraisal of the business ethics literature on Greater China. In (...) particular, it maps out the existing research findings, identifies limitations in methodology, and suggests future directions for business ethics research in this region. The findings indicate that the scholarly interests cover 24 research themes, including corporate social responsibility and social performance; ethical beliefs, judgment, values, decision-making, and culture; workplace ethics and behavior; marketing ethics and consumer behavior; and sustainability. This review reveals a growing imbalance between empirical and conceptual/theoretical studies on business ethics. In addition, the published works covered in this review heavily rely on survey method and convenience sampling, with a predominant focus on a single individual level of analysis. Importantly, this study identifies four directions for future research: contextualized theoretical development, addressing multilevel research, developing research design tailored to the Chinese context, and ensuring more diversified and rigorous data collection. (shrink)

This paper proposes an extended version of the interventionist account for causal inference in the practical context of biological mechanism research. This paper studies the details of biological mechanism researchers’ practices of assessing the evidential legitimacy of experimental data, arguing why quantity and variety are two important criteria for this assessment. Because of the nature of biological mechanism research, the epistemic values of these two criteria result from the independence both between the causation of data generation and the causation in (...) question and between different interventions, not techniques. The former independence ensures that the interventions in the causation in question are not affected by the causation that is responsible for data generation. The latter independence ensures the reliability of the final mechanisms not only in the empirical but also the formal aspects. This paper first explores how the researchers use quantity to check the effectiveness of interventions, where they at the same time determine the validity of the difference-making revealed by the results of interventions. Then, this paper draws a distinction between experimental interventions and experimental techniques, so that the reliability of mechanisms, as supported by the variety of evidence, can be safely ensured in the probabilistic sense. The latter process is where the researchers establish evidence of the mechanisms connecting the events of interest. By using case studies, this paper proposes to use ‘intervention’ as the fruitful connecting point of literature between evidence and mechanisms. (shrink)

The spatial organization of the genome is intimately linked to its biological function, yet our understanding of higher order genomic structure is coarse, fragmented and incomplete. In the nucleus of eukaryotic cells, interphase chromosomes occupy distinct.

An increasing body of institutional research has examined organizations’ response to conflicting institutional logics, but few studies have looked into how cross-sector organizational actors experiencing institutional complexity strategize their response mechanisms to create value in the context of corporate social responsibility (CSR). We conduct a comparative case study of nine social partnerships between multinational companies (MNCs) and nonprofits in China. We identify a partnership logic among the value-creating partnerships where partners guided by an either/and mindset take joint ownership of the (...) social or sustainability issue/cause and integrate it into their core set of activities and goals. By contrast, the less successful partnerships guided by an either/or mindset pursue a substitution logic in which the issue and project are kept separate and marginalized from core activities and goals. We contribute to an understanding of the value creation of cross-sector social partnerships by revealing the institutional embeddedness of such partnerships and deriving a process model of collaborative value creation through institutional works in social partnerships. (shrink)

Purpose – This study aims to investigate the perceptions, acceptance, usage and access to social media by students and academics in higher education in informatics programs in Malaysia. A conceptual model based on Connectivism and communities of practice learning theory was developed and were used as a basis of mapping the research questions to the design frameworks and the research outcomes. A significant outcome of this study will be the development of a design framework for implementing social media as supporting (...) tools for student engagement and teaching and learning of informatics programs in higher education institutions in Malaysia. Design/methodology/approach – A mixed-method research methodology with a significant survey research component was employed for this research. This methodology focused on collecting and analyzing quantitative and qualitative data to better understand the research problems. For this study, a mixed-method sequential transformative research strategy based on a QUAN-Qual model was used in the data collection process. Mixed-method research methodology is considered to be most appropriate for this study, as it allows the researcher to gather multiple forms of data from diverse audiences such as educators, administrators and students. Findings – The findings show the close matched of the ownership, amount of hours spent online, types of social media technologies used and pattern of usage between informatics and non-informatics students. It also shows that many students and instructors have started to explore and accept the use of SMTs as a tool for engaging with their institution and their peers as well as for teaching and learning purposes. Innovative institutions need to understand the critical success factors and the barriers that restrict the implementation of SMTs within the HEI to take advantage of the opportunities offered by SMTs in higher education. Research limitations/implications – The surveys and interview participant, in part, are self-selecting, so the data collected cannot be claimed to be representative of the population. However, because of the relatively large number of participants, it can be considered that the findings are indicative. Other limitation includes the depth of data that can be collected using this methodology. Practical implications – There is wide range of social media usage in educational settings now being reported, but many issues are still unexamined. Limited studies have been focusing on the educators’ readiness, acceptance or refusal in integrating social media into their courses, the perceived effectiveness of the tools and student outcomes for their learning. The central outcome of this research will be the development of a design framework that will be used as a guide for Malaysian HEIs and informatics academics to engage students using SMTs in creating effective learning communities for informatics programs. Social implications – The framework will have implication for the social interaction and engagement of students with their institution. Originality/value – Very little work has been reported on student and academic engagement, their perspectives and perceived effectiveness of social media usage in higher education, especially in the Malaysia context. Most of the research focused only on the quantitative research with students from universities in the USA and Australia, with an emphasis mainly on student’s perception and acceptance. There are calls for more research to examine how social media is perceived and accepted by students and academics for teaching and learning, especially in Malaysia. (shrink)

Projections regarding future energy consumption and carbon emissions are crucial when the aim is to design policy for global emissions control. What is the different models’ take on the projections for global emissions and, in particular, China’s role in the global picture? Do they anticipate similar results? If not, why are the results different? What key parameters do they use, and how do they affect the final findings? This Article attempts to answer these questions and, starting from there, to further (...) analyze what it means for the challenge of China’s future emissions reduction potential and for the overall goal of global emissions reduction. (shrink)