We have a reason to use information which is available about such genes in our reproductive decision-making; (3) couples should selec.

Brain organoid research raises ethical challenges not seen in other forms of stem cell research. Given that brain organoids partially recapitulate the development of the human brain, it is plausible that brain organoids could one day attain consciousness and perhaps even higher cognitive abilities. Brain organoid research therefore raises difficult questions about these organoids' moral status – questions that currently fall outside the scope of existing regulations and guidelines. This paper shows how these gaps can be addressed. We outline a (...) moral framework for brain organoid research that can address the relevant ethical concerns without unduly impeding this important area of research. (shrink)

Numerous high-profile ethics scandals, rising inequality, and the detrimental effects of climate change dramatically underscore the need for business schools to instill a commitment to social purpose in their students. At the same time, the rising financial burden of education, increasing competition in the education space, and overreliance on graduates’ financial success as the accepted metric of quality have reinforced an instrumentalist climate. These conflicting aims between social and financial purpose have created an existential crisis for business education. To resolve (...) this impasse, we draw on the concept of moral self-awareness to offer a system-theoretical strategy for crowding-in a culture of ethics within business schools. We argue that to do so, business schools will need to (1) reframe the purpose of business, (2) reframe the meaning of professional success, and (3) reframe the ethos of business education itself. (shrink)

This impressive volume of essays that includes contributions from Herbert Dreyfus, Sean Kelly, Mike Wheeler, Dan Zahavi, and Shaun Gallagher reflects an emerging trend in cognitive science, and explores this new approach to cognitive science informed by Heidegger's thoughts on human existence.

Antibiotic use in animal farming is one of the main drivers of antibiotic resistance both in animals and in humans. In this paper we propose that one feasible and fair way to address this problem is to tax animal products obtained with the use of antibiotics. We argue that such tax is supported both by deontological arguments, which are based on the duty individuals have to compensate society for the antibiotic resistance to which they are contributing through consumption of animal (...) products obtained with the use of antibiotics; and a cost-benefit analysis of taxing such animal products and of using revenue from the tax to fund alternatives to use of antibiotics in animal farming. Finally, we argue that such a tax would be fair because individuals who consume animal products obtained with the use of antibiotics can be held morally responsible, i.e. blameworthy, for their contribution to antibiotic resistance, in spite of the fact that each individual contribution is imperceptible. (shrink)

In this paper I consider, in connection with dementia, two views of the person. One view of the person is derived from Locke and Parfit. This tends to regard the person solely in terms of psychological states and his/her connections. The second view of the person is derived from a variety of thinkers. I have called it the situated-embodied-agent view of the person. This view, I suggest, more readily squares with the reality of clinical experience. It regards the person as (...) embedded in a history and culture. The human person is also an embodied agent. I contend that this view encourages a more appropriate approach towards the ethical issues that arise in dementia and towards people with dementia. (shrink)

I discuss a puzzle that shows there is a need to develop a new metaphysical interpretation of mathematical theories, because all well-known interpretations conflict with important aspects of mathematical activities. The new interpretation, I argue, must authenticate the ontological commitments of mathematical theories without curtailing mathematicians' freedom and authority to creatively introduce mathematical ontology during mathematical problem-solving. Further, I argue that these two constraints are best met by a metaphysical interpretation of mathematics that takes mathematical entities to be constitutively constructed (...) by human activity in a manner similar to the constitutive construction of the US Supreme Court by certain legal and political activities. Finally, I outline some of the philosophical merits of metaphysical interpretations of mathematical theories of this type. (shrink)

Drawing on a wide range of Kant's recorded thought beyond his Groundwork for the Metaphysics of Morals, this essay presents an overview of Kant's account of practical agency as embodied practical agency and argues against the intellectualized interpretations of Kant's account of practical agency presented by Christine Korsgaard and Henry Sidgwick. In both Kant's empirical-psychological and metaphysical descriptions of practical agency, he presents a recognizably human practical agent that is broader and deeper than the faculty of reason alone. This agent (...) chooses action from a reflective distance, but not from the complete affective distance of reason. We choose neither as reason alone, nor even as the sum of all of our ‘higher’ faculties, of cognition (including reason), feeling, and desire, in Kant's view. Instead, we choose as an agent that also has ‘lower’, ‘sensible’ faculties, of cognition (including sense), feeling, and desire, which together comprise our ‘sensibility’. These mental states of sensibility are not merely confused versions of our higher cognitions, feelings, or desires, and so different from them in degree only, but are instead distinct from our higher states in kind also; and these distinct sensible states are not dependent on our higher states and so on a commitment to the value of humanity, for example. For this reason, a choice in favour of sensible states and in opposition to the moral law need in no way undermine its own foundations and thus be incoherent, as Korsgaard and Sidgwick argue, but instead only immoral. Because Kant does not reduce the problem of immoral choice to one of insufficient reflection and ensuing confusion, he does not view moral progress in cognitive terms alone, whether in the form of a clearer understanding of the moral law, improved judgment in applying it, or deeper insight into our own nature as practical agents. Kant instead recognizes the crucial importance of cultivating our feelings and desires over the course of a lifetime both as a way to make ourselves worthy of the humanity within us directly and also as a way to facilitate future moral choices. (shrink)

Two aspects of the chromatin repeat length (r t) are discussed: (i) Why is r t, longer for slowly dividing cells than in rapidly dividing cells?, and (ii) Why is the temporal evolution of r ta decreasing function of time (t) in mammalian cortical neurons, whereas it is an increasing function of t for granule cells around the time of birth? These questions are discussed in terms of a hypothesis which assumes a correlation between deoxyribonucleic acid (DNA) packaging, transcription, and (...) replication. (shrink)

An earlier version of this paper was presented at the 2011 IEEE International Symposium on Technology and Society at Saint Xavier University in Chicago, Illinois. Perhaps the most remarkable characteristic of digital social games such as Zynga's FarmVille is that they are designed in such a way that any user, regardless of their skills and experience, can familiarise themselves in a matter of moments with the object of the game, the interface, and the tools and options involved in playing them. (...) In contrast, developers of collaborative platforms for teaching and research have been struggling for the last 15 to 20 years to gain a wide acceptance among users, and with very limited success. Although simple and intuitive usability has long been recognised as a key design goal, no-one has, apparently, yet succeeded in integrating all the tools and functions required for academic work into a platform with an intuitive interface that target groups make enthusiastic use of. This paper investigates which principles and features may be adopted to make the use of these platforms easier and more intuitive. This electronic document is a "live" template. The various components of your paper [title, text, heads, etc.] are already defined on the style sheet, as illustrated by the portions given in this document. (shrink)

The article shows the interlacement of political philosophy and philosophy of education by justifying educational justice as central normative ground for analyzing educational policies as well as by defending a democratic conception of educational justice. In order to ground the importance of the concept of educational justice, the article explains the shortcomings of the alternative – functionalist and liberal perfectionist – normative grounds of educational policy. Then, the article develops a democratic conception of educational justice by first of all criticizing (...) the liberal conception of equal educational opportunity on the ground that it implicitly accepts as valid the socially existing understanding of educational success. Based on this critique the article defends a democratic conception of educational justice that demands the institutionalization of educational practices that prepare students to define themselves as democratic citizens what educational success should mean. (shrink)

El propósito de este artículo es mostrar algunos aspectos ideológicos de la concepción de la tecnología y del ser humano que subyacen en el transhumanismo. Se intentan demostrar estos aspectos a la luz de la antropología filosófica de Scheler, Plessner y otros autores mediante los siguientes argumentos: la crítica a la concepción neutral de la tecnología, el rechazo de la idea del ser humano como homo faber y la errónea comprensión transhumanista de la vida y la muerte. A partir de (...) una puesta en discusión de este movimiento con la antropología filosófica se comprueba que no hay ningún cambio de paradigma dentro del transhumanismo y que las viejas concepciones del ser humano que habían sido defendidas por la Modernidad siguen estando presentes. (shrink)

Social relationships are essential for humans; neglecting our social needs can reduce wellbeing or even lead to the development of more severe issues such as depression or substance dependency. Although essential, some individuals face major challenges in forming and maintaining social relationships due to the experience of social anxiety. The burden of social anxiety can be reduced through accessible assessment that leads to treatment. However, socially anxious individuals who seek help face many barriers stemming from geography, fear, or disparities in (...) access to systems of care. But recent research suggested digital behavioral markers as a way to deliver cheap and easily accessible digital assessment for social anxiety: As earlier work shows, players with social anxiety show similar behaviors in virtual worlds as in the physical world, including tending to walk farther around other avatars and standing farther away from other avatars. The characteristics of the movement behavior in-game can be harnessed for the development of digital behavioral markers for the assessment of social anxiety. In this paper, we investigate whether implicit as well as explicit digital behavioral markers, proposed by prior work, for social anxiety can be used for predicting the level of social anxiety. We show that both, explicit and implicit digital behavioral markers can be harnessed for the assessment. Our findings provide further insights about how game-based digital behavioral markers can be used for the assessment of social anxiety. (shrink)

La verdad por definición es un tipo peculiar de verdad científica, distinguible de las verdades lógicas, matemáticas y empíricas. La definición, por su parte, designa diversos procedimientos de asignación de significado, cuyas diferencias exigen una adjetivación cuidadosa: definiciones ostensivas y operacionales, definiciones de diccionario y definiciones teóricas. Pero sólo las del último tipo son verdaderas por definición. En el presente artículo se precisa el concepto formal de definición teórica, se delimita la estructura de esos enunciados, se analiza la verdad por (...) definición, y se comparan, por último, las definiciones teóricas con los otros tipos de definición. (shrink)

Political Liberty is presently under stress for different reasons, two of them are: the erosion of civic culture and the policies chosen to restrict Covid-19. In this article I develop an account of political liberty that is bound to core concepts of humanistic anthropology and metaphysical freedom (I). On this conceptual basis I discuss two actual challenges of political liberty: cancel culture (II) and anti-pandemic state measures (III).

Analyses the concepts that underpin Ranciere's thought on literature, scrutinising his interpretations of particular works This collection of original essays engages with Ranciere's accounts of literature from across his body of work, putting his conceptual apparatus to work in acts of literary criticism. From his archival investigations of the literary efforts of 19th-century workers to his engagements with specific novelists and poets, and from his concept of 'literarity' to his central positioning of the novel in his account of the three (...) 'regimes' of literary practice, this collection unearths, consolidates, evaluates and critiques Ranciere's work on and with literature. ". (shrink)

Si bien mucho se ha escrito sobre la noción de lógos en Justino, hasta el momento no se la ha estudiado en relación con su concepción de la historia. Aquí nos proponemos poner de manifiesto esa relación descubriendo las premisas del “argumento supercesionista”. Por medio de éste, en efecto, es posible recuperar todas las verdades pre-cristianas, especialmente las de origen judaico, y aunarlas en una historia ininterrumpida desde el origen del mundo hasta la primera parousía. Nuestro trabajo se divide, así, (...) en tres partes. En la primera expondremos la noción de lógos, en la segunda examinaremos la reinterpretación de las relaciones entre Judaísmo y Cristianismo en la obra del mártir y en la tercera parte expondremos el argumento supercesionista dando cuenta de cómo opera en ésta la noción de lógos. (shrink)

This paper is a response to John Harris’ provocative ‘Justice and Equal Opportunities in Health Care’. The aim of this short response is to locate the difference between Harris and me within a broader debate about the nature of reasons for action. I argue that Harris is appealing to a desire‐based conception of normative reasons. I highlight some of the deficiencies of a desire‐based conception of reasons, and contrast it with a value‐based account.

BackgroundLight to moderate physical activity, which includes walking, is associated with positive effects on physical and mental health. However, concerning mental health, social and physical environmental factors are likely to play an important role in this association. This study investigates person-place interactions between environmental characteristics and momentary affective states during walking episodes. A within-subject design is implemented, in which affective states and environmental characteristics are assessed while participants are walking outside.MethodsOn smartphones, coupled with a motion sensor, e-diaries were triggered as (...) soon as people walked 100 m outside. E-diaries assessed momentary affective states, and social interaction between 6 am and 10 pm over nine days. The percentage of greenness was determined afterward from recorded GPS and GIS data. Demographics were collected in advance via an online questionnaire. Multilevel models were calculated with R for 46 individuals.ResultsAffective state dimension energetic arousal showed a significant association with social interaction and greenness, i.e., participants rated energetic arousal lower when walking alone, and if there was less greenness vs. when interacting shortly with someone while walking, and being in situations with more greenness. Furthermore, associations with social interaction and greenness were found for dimension calmness: walking together with someone was associated with higher calmness, and the higher the proportion of surrounding greenness during a walk, the higher calmness was rated, i.e., participants were calmer. Significant associations with valence were not present.ConclusionThe findings indicate that the affective states varied significantly due to different social and physical environmental factors. In the future, the importance of environmental factors should be further investigated, e.g., by assessing environmental factors right in situations contrary to a subsequent imputation. Within-subject designs, and in particular triggered assessments with the addition of GPS, can aid in developing interventions for health-promoting urban environments. (shrink)

A long-debated question in the philosophy of health, and contingent disciplines, is the extent to which wise clinical practice (“clinical wisdom”) is, or could be, compatible with empirically validated medicine (“evidence-based medicine”—EBM). Here we respond to Baum-Baicker and Sisti, who not only suggest that these two types of knowledge are divided due to their differing sources, but also that EBM can sometimes even hurt wise clinical practice. We argue that the distinction between EBM and clinical wisdom is poorly defined, unsupported (...) by the methodology employed, and ultimately incorrect; crucial differences exist, we argue, not in the source of a particular piece of clinical knowledge, but in its dependability. In light of this subtle but fundamental revision, we explain how clinical wisdom and EBM are—by necessity—complementary, rather than in conflict. We elaborate on how recognizing this relationship can have far-reaching implications for the domains of clinical practice, medical education, and health policy. (shrink)